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Found 264 of ph data with Target = 'Metabotropic glutamate receptor 2'
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM160795(US9682980, 8-Chloro-3-(cyclopropylmethyl)-7-(4-(2-...)
Affinity DataEC50:  36nMpH: 7.0Assay Description:Clonally expressed human mGluR2 in HEK293 background was glutamate starved overnight in media without glutamine (GIBCO MEM 12360), containing 10% FBS...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM160797(US9682980, 8-Chloro-3-(2,2,2-trifluoroethyl)-7-(4-...)
Affinity DataEC50:  23nMpH: 7.0Assay Description:Clonally expressed human mGluR2 in HEK293 background was glutamate starved overnight in media without glutamine (GIBCO MEM 12360), containing 10% FBS...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM160800(US9682980, 8-Chloro-7-(4-(2-fluorophenyl)piperidin...)
Affinity DataEC50:  5nMpH: 7.0Assay Description:Clonally expressed human mGluR2 in HEK293 background was glutamate starved overnight in media without glutamine (GIBCO MEM 12360), containing 10% FBS...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM160805(US9682980, 8-Chloro-3-(cyclopropylmethyl)-7-(4-(2-...)
Affinity DataEC50:  4nMpH: 7.0Assay Description:Clonally expressed human mGluR2 in HEK293 background was glutamate starved overnight in media without glutamine (GIBCO MEM 12360), containing 10% FBS...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM160806(US9682980, 8-Chloro-7-(4-(4-fluorophenyl)piperidin...)
Affinity DataEC50:  438nMpH: 7.0Assay Description:Clonally expressed human mGluR2 in HEK293 background was glutamate starved overnight in media without glutamine (GIBCO MEM 12360), containing 10% FBS...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM160807(US9682980, 3-(Cyclopropylmethyl)-7-(4-(2-fluoro-6-...)
Affinity DataEC50:  3nMpH: 7.0Assay Description:Clonally expressed human mGluR2 in HEK293 background was glutamate starved overnight in media without glutamine (GIBCO MEM 12360), containing 10% FBS...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM160807(US9682980, 3-(Cyclopropylmethyl)-7-(4-(2-fluoro-6-...)
Affinity DataEC50:  4nMpH: 7.0Assay Description:Clonally expressed human mGluR2 in HEK293 background was glutamate starved overnight in media without glutamine (GIBCO MEM 12360), containing 10% FBS...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM160810(US9682980, 2-(1-(8-Chloro-3-(cyclopropylmethyl)-[1...)
Affinity DataEC50:  15nMpH: 7.0Assay Description:Clonally expressed human mGluR2 in HEK293 background was glutamate starved overnight in media without glutamine (GIBCO MEM 12360), containing 10% FBS...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM160811(US9682980, 2-(1-(8-chloro-3-(2,2,2-trifluoroethyl)...)
Affinity DataEC50:  18nMpH: 7.0Assay Description:Clonally expressed human mGluR2 in HEK293 background was glutamate starved overnight in media without glutamine (GIBCO MEM 12360), containing 10% FBS...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM160812(US9682980, 8-Chloro-3-(cyclopropylmethyl)-7-(4-(2,...)
Affinity DataEC50:  14nMpH: 7.0Assay Description:Clonally expressed human mGluR2 in HEK293 background was glutamate starved overnight in media without glutamine (GIBCO MEM 12360), containing 10% FBS...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM160814(US9682980, 8-Chloro-7-(4-(2,4-difluorophenyl)piper...)
Affinity DataEC50:  16nMpH: 7.0Assay Description:Clonally expressed human mGluR2 in HEK293 background was glutamate starved overnight in media without glutamine (GIBCO MEM 12360), containing 10% FBS...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM160815(US9682980, 8-Chloro-3-(cyclopropylmethyl)-7-(4-(3-...)
Affinity DataEC50:  34nMpH: 7.0Assay Description:Clonally expressed human mGluR2 in HEK293 background was glutamate starved overnight in media without glutamine (GIBCO MEM 12360), containing 10% FBS...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM160817(US9682980, 2-(1-(3-(Cyclopropylmethyl)-8-(trifluor...)
Affinity DataEC50:  4nMpH: 7.0Assay Description:Clonally expressed human mGluR2 in HEK293 background was glutamate starved overnight in media without glutamine (GIBCO MEM 12360), containing 10% FBS...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM160818(US9682980, 2-(1-(3-(2,2,2-Trifluoroethyl)-8-(trifl...)
Affinity DataEC50:  7nMpH: 7.0Assay Description:Clonally expressed human mGluR2 in HEK293 background was glutamate starved overnight in media without glutamine (GIBCO MEM 12360), containing 10% FBS...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM160820(US9682980, 8-Chloro-3-(cyclopropylmethyl)-7-(4-(py...)
Affinity DataEC50:  382nMpH: 7.0Assay Description:Clonally expressed human mGluR2 in HEK293 background was glutamate starved overnight in media without glutamine (GIBCO MEM 12360), containing 10% FBS...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM160821(US9682980, 3-(Cyclopropylmethyl)-7-(4-(3,6-difluor...)
Affinity DataEC50:  0.200nMpH: 7.0Assay Description:Clonally expressed human mGluR2 in HEK293 background was glutamate starved overnight in media without glutamine (GIBCO MEM 12360), containing 10% FBS...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM160822(US9682980, 7-(4-(3,6-Difluoro-2-methoxyphenyl)pipe...)
Affinity DataEC50:  0.400nMpH: 7.0Assay Description:Clonally expressed human mGluR2 in HEK293 background was glutamate starved overnight in media without glutamine (GIBCO MEM 12360), containing 10% FBS...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM160823(US9682980, 8-Chloro-3-(cyclopropylmethyl)-7-(4-(py...)
Affinity DataEC50:  809nMpH: 7.0Assay Description:Clonally expressed human mGluR2 in HEK293 background was glutamate starved overnight in media without glutamine (GIBCO MEM 12360), containing 10% FBS...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM160825(US9682980, 8-Chloro-7-(4-(3-methoxypyridin-2-yl)pi...)
Affinity DataEC50:  42nMpH: 7.0Assay Description:Clonally expressed human mGluR2 in HEK293 background was glutamate starved overnight in media without glutamine (GIBCO MEM 12360), containing 10% FBS...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM160826(US9682980, 3-(Cyclopropylmethyl)-7-(4-(2-fluorophe...)
Affinity DataEC50:  4nMpH: 7.0Assay Description:Clonally expressed human mGluR2 in HEK293 background was glutamate starved overnight in media without glutamine (GIBCO MEM 12360), containing 10% FBS...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM160828(US9682980, Trans-N-((2-(2-methoxyphenyl)cyclopropy...)
Affinity DataEC50:  10nMpH: 7.0Assay Description:Clonally expressed human mGluR2 in HEK293 background was glutamate starved overnight in media without glutamine (GIBCO MEM 12360), containing 10% FBS...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM160547(US9682980, 8-Chloro-3-(cyclopropylmethyl)-7-(4-phe...)
Affinity DataEC50:  8nMpH: 7.0Assay Description:Clonally expressed human mGluR2 in HEK293 background was glutamate starved overnight in media without glutamine (GIBCO MEM 12360), containing 10% FBS...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM160555(US9682980, 3-(Cyclopropylmethyl)-8-methyl-7-(4-phe...)
Affinity DataEC50:  62nMpH: 7.0Assay Description:Clonally expressed human mGluR2 in HEK293 background was glutamate starved overnight in media without glutamine (GIBCO MEM 12360), containing 10% FBS...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM160556(US9682980, 3-(Cyclopropylmethyl)-7-(4-(4-fluorophe...)
Affinity DataEC50:  540nMpH: 7.0Assay Description:Clonally expressed human mGluR2 in HEK293 background was glutamate starved overnight in media without glutamine (GIBCO MEM 12360), containing 10% FBS...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM160557(US9682980, 3-(Cyclopropylmethyl)-7-(4-phenylpiperi...)
Affinity DataEC50:  69nMpH: 7.0Assay Description:Clonally expressed human mGluR2 in HEK293 background was glutamate starved overnight in media without glutamine (GIBCO MEM 12360), containing 10% FBS...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM160562(US9682980, 8-Chloro-3-(cyclopropylmethyl)-7-(4-phe...)
Affinity DataEC50:  19nMpH: 7.0Assay Description:Clonally expressed human mGluR2 in HEK293 background was glutamate starved overnight in media without glutamine (GIBCO MEM 12360), containing 10% FBS...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM160566(US9682980, 3-(Cyclopropylmethyl)-8-methyl-7-(4-phe...)
Affinity DataEC50:  182nMpH: 7.0Assay Description:Clonally expressed human mGluR2 in HEK293 background was glutamate starved overnight in media without glutamine (GIBCO MEM 12360), containing 10% FBS...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM160573(US9682980, 3-(Cyclopropylmethyl)-7-(4-phenylpiperi...)
Affinity DataEC50:  3nMpH: 7.0Assay Description:Clonally expressed human mGluR2 in HEK293 background was glutamate starved overnight in media without glutamine (GIBCO MEM 12360), containing 10% FBS...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM160574(US9682980, 7-(4-Benzylpiperidin-1-yl)-8-chloro-3-(...)
Affinity DataEC50:  61nMpH: 7.0Assay Description:Clonally expressed human mGluR2 in HEK293 background was glutamate starved overnight in media without glutamine (GIBCO MEM 12360), containing 10% FBS...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM160605(US9682980, Trans-8-chloro-3-(cyclopropylmethyl)-N-...)
Affinity DataEC50:  76nMpH: 7.0Assay Description:Clonally expressed human mGluR2 in HEK293 background was glutamate starved overnight in media without glutamine (GIBCO MEM 12360), containing 10% FBS...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM160615(US9682980, 8-Chloro-3-(cyclopropylmethyl)-N-(((1R,...)
Affinity DataEC50:  158nMpH: 7.0Assay Description:Clonally expressed human mGluR2 in HEK293 background was glutamate starved overnight in media without glutamine (GIBCO MEM 12360), containing 10% FBS...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM160641(US9682980, 8-Chloro-3-(cyclopropylmethyl)-N-(((1S,...)
Affinity DataEC50:  60nMpH: 7.0Assay Description:Clonally expressed human mGluR2 in HEK293 background was glutamate starved overnight in media without glutamine (GIBCO MEM 12360), containing 10% FBS...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM160556(US9682980, 3-(Cyclopropylmethyl)-7-(4-(4-fluorophe...)
Affinity DataEC50:  519nMpH: 7.0Assay Description:Clonally expressed human mGluR2 in HEK293 background was glutamate starved overnight in media without glutamine (GIBCO MEM 12360), containing 10% FBS...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM160719(US9682980, 7-(4-(4-Fluorophenyl)piperidin-1-yl)-8-...)
Affinity DataEC50:  286nMpH: 7.0Assay Description:Clonally expressed human mGluR2 in HEK293 background was glutamate starved overnight in media without glutamine (GIBCO MEM 12360), containing 10% FBS...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM160720(US9682980, 1-(3-(Cyclopropylmethyl)-8-methoxy-[1,2...)
Affinity DataEC50:  782nMpH: 7.0Assay Description:Clonally expressed human mGluR2 in HEK293 background was glutamate starved overnight in media without glutamine (GIBCO MEM 12360), containing 10% FBS...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM160721(US9682980, 8-Chloro-3-(cyclopropylmethyl)-7-(4-(py...)
Affinity DataEC50:  280nMpH: 7.0Assay Description:Clonally expressed human mGluR2 in HEK293 background was glutamate starved overnight in media without glutamine (GIBCO MEM 12360), containing 10% FBS...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM160723(US9682980, 8-Chloro-3-neopentyl-7-(4-(pyrimidin-2-...)
Affinity DataEC50:  437nMpH: 7.0Assay Description:Clonally expressed human mGluR2 in HEK293 background was glutamate starved overnight in media without glutamine (GIBCO MEM 12360), containing 10% FBS...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM160724(US9682980, 8-Chloro-3-(cyclopropylmethyl)-7-(4-(4-...)
Affinity DataEC50:  46nMpH: 7.0Assay Description:Clonally expressed human mGluR2 in HEK293 background was glutamate starved overnight in media without glutamine (GIBCO MEM 12360), containing 10% FBS...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM160725(US9682980, 8-Chloro-7-(4-(4-fluorophenyl)piperidin...)
Affinity DataEC50:  145nMpH: 7.0Assay Description:Clonally expressed human mGluR2 in HEK293 background was glutamate starved overnight in media without glutamine (GIBCO MEM 12360), containing 10% FBS...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM160727(US9682980, 8-Chloro-3-(cyclopropylmethyl)-7-(4-(4-...)
Affinity DataEC50:  614nMpH: 7.0Assay Description:Clonally expressed human mGluR2 in HEK293 background was glutamate starved overnight in media without glutamine (GIBCO MEM 12360), containing 10% FBS...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM160729(US9682980, 8-Chloro-3-(cyclopropylmethyl)-7-(spiro...)
Affinity DataEC50:  145nMpH: 7.0Assay Description:Clonally expressed human mGluR2 in HEK293 background was glutamate starved overnight in media without glutamine (GIBCO MEM 12360), containing 10% FBS...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM160738(US9682980, 8-Chloro-3-(cyclopropylmethyl)-N-((1-(p...)
Affinity DataEC50:  2.31E+3nMpH: 7.0Assay Description:Clonally expressed human mGluR2 in HEK293 background was glutamate starved overnight in media without glutamine (GIBCO MEM 12360), containing 10% FBS...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM160739(US9682980, 8-Chloro-3-(cyclopropylmethyl)-7-(4-(2-...)
Affinity DataEC50:  3nMpH: 7.0Assay Description:Clonally expressed human mGluR2 in HEK293 background was glutamate starved overnight in media without glutamine (GIBCO MEM 12360), containing 10% FBS...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM160740(US9682980, 8-Chloro-3-(cyclopropylmethyl)-7-(4-(2-...)
Affinity DataEC50:  13nMpH: 7.0Assay Description:Clonally expressed human mGluR2 in HEK293 background was glutamate starved overnight in media without glutamine (GIBCO MEM 12360), containing 10% FBS...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM160741(US9682980, 8-Chloro-3-(cyclopropylmethyl)-7-(4-(3-...)
Affinity DataEC50:  25nMpH: 7.0Assay Description:Clonally expressed human mGluR2 in HEK293 background was glutamate starved overnight in media without glutamine (GIBCO MEM 12360), containing 10% FBS...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM160742(US9682980, 8-Chloro-7-(4-(2-fluorophenyl)piperidin...)
Affinity DataEC50:  20nMpH: 7.0Assay Description:Clonally expressed human mGluR2 in HEK293 background was glutamate starved overnight in media without glutamine (GIBCO MEM 12360), containing 10% FBS...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM160743(US9682980, 8-Chloro-7-(4-(2-fluoro-6-methoxyphenyl...)
Affinity DataEC50:  2nMpH: 7.0Assay Description:Clonally expressed human mGluR2 in HEK293 background was glutamate starved overnight in media without glutamine (GIBCO MEM 12360), containing 10% FBS...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM160744(US9682980, 8-Chloro-3-(cyclopropylmethyl)-7-(4-(2-...)
Affinity DataEC50:  9nMpH: 7.0Assay Description:Clonally expressed human mGluR2 in HEK293 background was glutamate starved overnight in media without glutamine (GIBCO MEM 12360), containing 10% FBS...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM160745(US9682980, 8-Chloro-3-(cyclopropylmethyl)-7-(4-(3-...)
Affinity DataEC50:  38nMpH: 7.0Assay Description:Clonally expressed human mGluR2 in HEK293 background was glutamate starved overnight in media without glutamine (GIBCO MEM 12360), containing 10% FBS...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM160746(US9682980, 8-Chloro-3-(cyclopropylmethyl)-7-(4-(o-...)
Affinity DataEC50:  21nMpH: 7.0Assay Description:Clonally expressed human mGluR2 in HEK293 background was glutamate starved overnight in media without glutamine (GIBCO MEM 12360), containing 10% FBS...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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