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Compile Data Set for Download or QSAR

Found 139 hits of ph data with Target = 'Methionine aminopeptidase 2'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Methionine aminopeptidase 2


(Homo sapiens (human))
BDBM36588
PNG
(AGM-1470)
Show SMILES CO[C@@H]1[C@@H](CC[C@]2(CO2)C1[C@]1(C)OC1CC=C(C)C)OC(=O)NC(=O)CCl
Show InChI InChI=1S/C19H28ClNO6/c1-11(2)5-6-13-18(3,27-13)16-15(24-4)12(7-8-19(16)10-25-19)26-17(23)21-14(22)9-20/h5,12-13,15-16H,6-10H2,1-4H3,(H,21,22,23)/t12-,13?,15-,16?,18-,19+/m1/s1
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n/an/a 1n/an/an/an/a7.3537



Massachusetts Institute of Technology



Assay Description
Enzymatic assay using recombinant human type 2 methionine aminopeptidase (MetAP2).


Chem Biol 4: 461-71 (1997)


Article DOI: 10.1124/jpet.103.062398
BindingDB Entry DOI: 10.7270/Q2NG4P04
More data for this
Ligand-Target Pair
3D
3D Structure (docked)
Methionine aminopeptidase 2


(Homo sapiens (human))
BDBM36589
PNG
(Ovalicin)
Show SMILES CO[C@@H]1C(=O)CC[C@]2(CO2)[C@@]1(O)[C@]1(C)OC1CC=C(C)C
Show InChI InChI=1S/C16H24O5/c1-10(2)5-6-12-14(3,21-12)16(18)13(19-4)11(17)7-8-15(16)9-20-15/h5,12-13,18H,6-9H2,1-4H3/t12?,13-,14-,15+,16+/m1/s1
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n/an/a 0.400n/an/an/an/a7.3537



Massachusetts Institute of Technology



Assay Description
Enzymatic assay using recombinant human type 2 methionine aminopeptidase (MetAP2).


Chem Biol 4: 461-71 (1997)


Article DOI: 10.1124/jpet.103.062398
BindingDB Entry DOI: 10.7270/Q2NG4P04
More data for this
Ligand-Target Pair
3D
3D Structure (docked)
Methionine aminopeptidase 2


(Homo sapiens (human))
BDBM36590
PNG
(FOS-72)
Show SMILES CO[C@H]1C([C@]2(C)OC2CC=C(C)C)[C@@]2(CO2)CCC1=O
Show InChI InChI=1S/C16H24O4/c1-10(2)5-6-12-15(3,20-12)14-13(18-4)11(17)7-8-16(14)9-19-16/h5,12-14H,6-9H2,1-4H3/t12?,13-,14?,15-,16+/m1/s1
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n/an/a 6n/an/an/an/a7.3537



Massachusetts Institute of Technology



Assay Description
Enzymatic assay using recombinant human type 2 methionine aminopeptidase (MetAP2).


Chem Biol 4: 461-71 (1997)


Article DOI: 10.1124/jpet.103.062398
BindingDB Entry DOI: 10.7270/Q2NG4P04
More data for this
Ligand-Target Pair
Methionine aminopeptidase 2


(Homo sapiens (human))
BDBM36595
PNG
(FOS-68)
Show SMILES CO[C@@H]1[C@@H](CC[C@]2(CO2)[C@@]1(O)[C@]1(C)OC1CC=C(C)C)OC(=O)NC(=O)CCl
Show InChI InChI=1S/C19H28ClNO7/c1-11(2)5-6-13-17(3,28-13)19(24)15(25-4)12(7-8-18(19)10-26-18)27-16(23)21-14(22)9-20/h5,12-13,15,24H,6-10H2,1-4H3,(H,21,22,23)/t12-,13?,15-,17-,18+,19+/m1/s1
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n/an/a 2n/an/an/an/a7.3537



Massachusetts Institute of Technology



Assay Description
Enzymatic assay using recombinant human type 2 methionine aminopeptidase (MetAP2).


Chem Biol 4: 461-71 (1997)


Article DOI: 10.1124/jpet.103.062398
BindingDB Entry DOI: 10.7270/Q2NG4P04
More data for this
Ligand-Target Pair
3D
3D Structure (docked)
Methionine aminopeptidase 2


(Homo sapiens (human))
BDBM36597
PNG
(FOS-69)
Show SMILES CO[C@@H]1[C@@H](CC[C@]2(CO2)[C@@]1(O)[C@]1(C)OC1CC=C(C)C)OC(=O)CCCCl
Show InChI InChI=1S/C20H31ClO6/c1-13(2)7-8-15-18(3,27-15)20(23)17(24-4)14(9-10-19(20)12-25-19)26-16(22)6-5-11-21/h7,14-15,17,23H,5-6,8-12H2,1-4H3/t14-,15?,17-,18-,19+,20+/m1/s1
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n/an/a 0.100n/an/an/an/a7.3537



Massachusetts Institute of Technology



Assay Description
Enzymatic assay using recombinant human type 2 methionine aminopeptidase (MetAP2).


Chem Biol 4: 461-71 (1997)


Article DOI: 10.1124/jpet.103.062398
BindingDB Entry DOI: 10.7270/Q2NG4P04
More data for this
Ligand-Target Pair
3D
3D Structure (docked)
Methionine aminopeptidase 2


(Homo sapiens (human))
BDBM36594
PNG
(FOS-202)
Show SMILES CO[C@@H]1[C@H](O)CC[C@](O)(SC)C1[C@]1(C)OC1CC=C(C)C
Show InChI InChI=1S/C16H28O4S/c1-10(2)6-7-12-15(3,20-12)14-13(19-4)11(17)8-9-16(14,18)21-5/h6,11-14,17-18H,7-9H2,1-5H3/t11-,12?,13-,14?,15-,16+/m1/s1
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n/an/a 5.00E+3n/an/an/an/a7.3537



Massachusetts Institute of Technology



Assay Description
Enzymatic assay using recombinant human type 2 methionine aminopeptidase (MetAP2).


Chem Biol 4: 461-71 (1997)


Article DOI: 10.1124/jpet.103.062398
BindingDB Entry DOI: 10.7270/Q2NG4P04
More data for this
Ligand-Target Pair
Methionine aminopeptidase 2


(Homo sapiens (human))
BDBM36591
PNG
(FOS-37)
Show SMILES CO[C@@H]1[C@H](O)CC[C@]2(CO2)C1[C@]1(C)OC1CC=C(C)C
Show InChI InChI=1S/C16H26O4/c1-10(2)5-6-12-15(3,20-12)14-13(18-4)11(17)7-8-16(14)9-19-16/h5,11-14,17H,6-9H2,1-4H3/t11-,12?,13-,14?,15-,16+/m1/s1
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n/an/a 8n/an/an/an/a7.3537



Massachusetts Institute of Technology



Assay Description
Enzymatic assay using recombinant human type 2 methionine aminopeptidase (MetAP2).


Chem Biol 4: 461-71 (1997)


Article DOI: 10.1124/jpet.103.062398
BindingDB Entry DOI: 10.7270/Q2NG4P04
More data for this
Ligand-Target Pair
3D
3D Structure (docked)
Methionine aminopeptidase 2


(Homo sapiens (human))
BDBM36596
PNG
(FOS-34)
Show SMILES CO[C@@H]1[C@H](O)CC[C@]2(CO2)[C@@]1(O)[C@]1(C)OC1CC=C(C)C
Show InChI InChI=1S/C16H26O5/c1-10(2)5-6-12-14(3,21-12)16(18)13(19-4)11(17)7-8-15(16)9-20-15/h5,11-13,17-18H,6-9H2,1-4H3/t11-,12?,13-,14-,15+,16+/m1/s1
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n/an/a 4n/an/an/an/a7.3537



Massachusetts Institute of Technology



Assay Description
Enzymatic assay using recombinant human type 2 methionine aminopeptidase (MetAP2).


Chem Biol 4: 461-71 (1997)


Article DOI: 10.1124/jpet.103.062398
BindingDB Entry DOI: 10.7270/Q2NG4P04
More data for this
Ligand-Target Pair
3D
3D Structure (docked)
Methionine aminopeptidase 2


(Homo sapiens (human))
BDBM36593
PNG
(FOS-64)
Show SMILES CO[C@@H]1[C@@H](CC[C@](O)(SC)C1[C@]1(C)OC1CC=C(C)C)OC(=O)NC(=O)CCl
Show InChI InChI=1S/C19H30ClNO6S/c1-11(2)6-7-13-18(3,27-13)16-15(25-4)12(8-9-19(16,24)28-5)26-17(23)21-14(22)10-20/h6,12-13,15-16,24H,7-10H2,1-5H3,(H,21,22,23)/t12-,13?,15-,16?,18-,19+/m1/s1
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n/an/a 3.00E+3n/an/an/an/a7.3537



Massachusetts Institute of Technology



Assay Description
Enzymatic assay using recombinant human type 2 methionine aminopeptidase (MetAP2).


Chem Biol 4: 461-71 (1997)


Article DOI: 10.1124/jpet.103.062398
BindingDB Entry DOI: 10.7270/Q2NG4P04
More data for this
Ligand-Target Pair
Methionine aminopeptidase 2


(Homo sapiens (human))
BDBM36599
PNG
(FOS-201)
Show SMILES CO[C@@H]1[C@H](O)CC[C@](O)(SC)[C@@]1(O)[C@]1(C)OC1CC=C(C)C
Show InChI InChI=1S/C16H28O5S/c1-10(2)6-7-12-14(3,21-12)16(19)13(20-4)11(17)8-9-15(16,18)22-5/h6,11-13,17-19H,7-9H2,1-5H3/t11-,12?,13-,14-,15+,16+/m1/s1
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n/an/a 45n/an/an/an/a7.3537



Massachusetts Institute of Technology



Assay Description
Enzymatic assay using recombinant human type 2 methionine aminopeptidase (MetAP2).


Chem Biol 4: 461-71 (1997)


Article DOI: 10.1124/jpet.103.062398
BindingDB Entry DOI: 10.7270/Q2NG4P04
More data for this
Ligand-Target Pair
Methionine aminopeptidase 2


(Homo sapiens (human))
BDBM36592
PNG
(FOS-70)
Show SMILES CO[C@@H]1[C@@H](CC[C@]2(CO2)C1[C@]1(C)OC1CC=C(C)C)OC(=O)CCCCl
Show InChI InChI=1S/C20H31ClO5/c1-13(2)7-8-15-19(3,26-15)18-17(23-4)14(9-10-20(18)12-24-20)25-16(22)6-5-11-21/h7,14-15,17-18H,5-6,8-12H2,1-4H3/t14-,15?,17-,18?,19-,20+/m1/s1
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n/an/a 3.5n/an/an/an/a7.3537



Massachusetts Institute of Technology



Assay Description
Enzymatic assay using recombinant human type 2 methionine aminopeptidase (MetAP2).


Chem Biol 4: 461-71 (1997)


Article DOI: 10.1124/jpet.103.062398
BindingDB Entry DOI: 10.7270/Q2NG4P04
More data for this
Ligand-Target Pair
Methionine aminopeptidase 2


(Homo sapiens (human))
BDBM17614
PNG
(5,6-disubstituted anthranilic acid sulfonamide, 9f...)
Show SMILES Cc1c(CO)ccc(NS(=O)(=O)c2ccc(F)cc2)c1C(O)=O
Show InChI InChI=1S/C15H14FNO5S/c1-9-10(8-18)2-7-13(14(9)15(19)20)17-23(21,22)12-5-3-11(16)4-6-12/h2-7,17-18H,8H2,1H3,(H,19,20)
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n/an/a 8.00E+3n/an/an/an/a7.422



Abbott Laboratories



Assay Description
A coupled enzyme chromogenic assay was developed to measure methionine aminopeptidase-2 activity by monitoring the production of free methionine with...


Bioorg Med Chem Lett 17: 2817-22 (2007)


Article DOI: 10.1016/j.bmcl.2007.02.062
BindingDB Entry DOI: 10.7270/Q2PK0DD1
More data for this
Ligand-Target Pair
Methionine aminopeptidase 2


(Homo sapiens (human))
BDBM17615
PNG
(5,6-disubstituted anthranilic acid sulfonamide, 9g...)
Show SMILES CC(O)c1ccc(NS(=O)(=O)c2ccc(F)cc2)c(C(O)=O)c1C
Show InChI InChI=1S/C16H16FNO5S/c1-9-13(10(2)19)7-8-14(15(9)16(20)21)18-24(22,23)12-5-3-11(17)4-6-12/h3-8,10,18-19H,1-2H3,(H,20,21)
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n/an/a 2.50E+3n/an/an/an/a7.422



Abbott Laboratories



Assay Description
A coupled enzyme chromogenic assay was developed to measure methionine aminopeptidase-2 activity by monitoring the production of free methionine with...


Bioorg Med Chem Lett 17: 2817-22 (2007)


Article DOI: 10.1016/j.bmcl.2007.02.062
BindingDB Entry DOI: 10.7270/Q2PK0DD1
More data for this
Ligand-Target Pair
Methionine aminopeptidase 2


(Homo sapiens (human))
BDBM17617
PNG
(5,6-disubstituted anthranilic acid sulfonamide, 9i...)
Show SMILES COc1c(ccc(NS(=O)(=O)c2ccc(F)cc2)c1C(O)=O)-c1ccoc1
Show InChI InChI=1S/C18H14FNO6S/c1-25-17-14(11-8-9-26-10-11)6-7-15(16(17)18(21)22)20-27(23,24)13-4-2-12(19)3-5-13/h2-10,20H,1H3,(H,21,22)
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n/an/a 8n/an/an/an/a7.422



Abbott Laboratories



Assay Description
A coupled enzyme chromogenic assay was developed to measure methionine aminopeptidase-2 activity by monitoring the production of free methionine with...


Bioorg Med Chem Lett 17: 2817-22 (2007)


Article DOI: 10.1016/j.bmcl.2007.02.062
BindingDB Entry DOI: 10.7270/Q2PK0DD1
More data for this
Ligand-Target Pair
Methionine aminopeptidase 2


(Homo sapiens (human))
BDBM17618
PNG
(5,6-disubstituted anthranilic acid sulfonamide, 9j...)
Show SMILES COc1c(ccc(NS(=O)(=O)c2ccc(F)cc2Br)c1C(O)=O)-c1ccoc1
Show InChI InChI=1S/C18H13BrFNO6S/c1-26-17-12(10-6-7-27-9-10)3-4-14(16(17)18(22)23)21-28(24,25)15-5-2-11(20)8-13(15)19/h2-9,21H,1H3,(H,22,23)
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n/an/a 20n/an/an/an/a7.422



Abbott Laboratories



Assay Description
A coupled enzyme chromogenic assay was developed to measure methionine aminopeptidase-2 activity by monitoring the production of free methionine with...


Bioorg Med Chem Lett 17: 2817-22 (2007)


Article DOI: 10.1016/j.bmcl.2007.02.062
BindingDB Entry DOI: 10.7270/Q2PK0DD1
More data for this
Ligand-Target Pair
Methionine aminopeptidase 2


(Homo sapiens (human))
BDBM17619
PNG
(5,6-disubstituted anthranilic acid sulfonamide, 9k...)
Show SMILES COc1c(ccc(NS(=O)(=O)c2ccc(F)cc2Br)c1C(O)=O)-c1ccco1
Show InChI InChI=1S/C18H13BrFNO6S/c1-26-17-11(14-3-2-8-27-14)5-6-13(16(17)18(22)23)21-28(24,25)15-7-4-10(20)9-12(15)19/h2-9,21H,1H3,(H,22,23)
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n/an/a 1.00E+3n/an/an/an/a7.422



Abbott Laboratories



Assay Description
A coupled enzyme chromogenic assay was developed to measure methionine aminopeptidase-2 activity by monitoring the production of free methionine with...


Bioorg Med Chem Lett 17: 2817-22 (2007)


Article DOI: 10.1016/j.bmcl.2007.02.062
BindingDB Entry DOI: 10.7270/Q2PK0DD1
More data for this
Ligand-Target Pair
Methionine aminopeptidase 2


(Homo sapiens (human))
BDBM17620
PNG
(5,6-disubstituted anthranilic acid sulfonamide, 9l...)
Show SMILES COc1c(ccc(NS(=O)(=O)c2ccc(F)cc2Br)c1C(O)=O)-c1c[nH]cn1
Show InChI InChI=1S/C17H13BrFN3O5S/c1-27-16-10(13-7-20-8-21-13)3-4-12(15(16)17(23)24)22-28(25,26)14-5-2-9(19)6-11(14)18/h2-8,22H,1H3,(H,20,21)(H,23,24)
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n/an/a 3.60E+4n/an/an/an/a7.422



Abbott Laboratories



Assay Description
A coupled enzyme chromogenic assay was developed to measure methionine aminopeptidase-2 activity by monitoring the production of free methionine with...


Bioorg Med Chem Lett 17: 2817-22 (2007)


Article DOI: 10.1016/j.bmcl.2007.02.062
BindingDB Entry DOI: 10.7270/Q2PK0DD1
More data for this
Ligand-Target Pair
Methionine aminopeptidase 2


(Homo sapiens (human))
BDBM17621
PNG
(5,6-disubstituted anthranilic acid sulfonamide, 9m...)
Show SMILES COc1c(ccc(NS(=O)(=O)c2ccc(F)cc2)c1C(O)=O)-c1cn[nH]c1
Show InChI InChI=1S/C17H14FN3O5S/c1-26-16-13(10-8-19-20-9-10)6-7-14(15(16)17(22)23)21-27(24,25)12-4-2-11(18)3-5-12/h2-9,21H,1H3,(H,19,20)(H,22,23)
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n/an/a 280n/an/an/an/a7.422



Abbott Laboratories



Assay Description
A coupled enzyme chromogenic assay was developed to measure methionine aminopeptidase-2 activity by monitoring the production of free methionine with...


Bioorg Med Chem Lett 17: 2817-22 (2007)


Article DOI: 10.1016/j.bmcl.2007.02.062
BindingDB Entry DOI: 10.7270/Q2PK0DD1
More data for this
Ligand-Target Pair
Methionine aminopeptidase 2


(Homo sapiens (human))
BDBM17622
PNG
(2-chloro-3-ethyl-6-[(4-fluorobenzene)sulfonamido]b...)
Show SMILES CCc1ccc(NS(=O)(=O)c2ccc(F)cc2)c(C(O)=O)c1Cl
Show InChI InChI=1S/C15H13ClFNO4S/c1-2-9-3-8-12(13(14(9)16)15(19)20)18-23(21,22)11-6-4-10(17)5-7-11/h3-8,18H,2H2,1H3,(H,19,20)
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n/an/a 15n/an/an/an/a7.422



Abbott Laboratories



Assay Description
A coupled enzyme chromogenic assay was developed to measure methionine aminopeptidase-2 activity by monitoring the production of free methionine with...


Bioorg Med Chem Lett 17: 2817-22 (2007)


Article DOI: 10.1016/j.bmcl.2007.02.062
BindingDB Entry DOI: 10.7270/Q2PK0DD1
More data for this
Ligand-Target Pair
Methionine aminopeptidase 2


(Homo sapiens (human))
BDBM17623
PNG
(5,6-disubstituted anthranilic acid sulfonamide, 9o...)
Show SMILES CCc1ccc(NS(=O)(=O)c2ccc(F)cc2)c(c1)C(O)=O
Show InChI InChI=1S/C15H14FNO4S/c1-2-10-3-8-14(13(9-10)15(18)19)17-22(20,21)12-6-4-11(16)5-7-12/h3-9,17H,2H2,1H3,(H,18,19)
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n/an/a 55n/an/an/an/a7.422



Abbott Laboratories



Assay Description
A coupled enzyme chromogenic assay was developed to measure methionine aminopeptidase-2 activity by monitoring the production of free methionine with...


Bioorg Med Chem Lett 17: 2817-22 (2007)


Article DOI: 10.1016/j.bmcl.2007.02.062
BindingDB Entry DOI: 10.7270/Q2PK0DD1
More data for this
Ligand-Target Pair
Methionine aminopeptidase 2


(Homo sapiens (human))
BDBM17616
PNG
(3-ethyl-6-[(4-fluorobenzene)sulfonamido]-2-methoxy...)
Show SMILES CCc1ccc(NS(=O)(=O)c2ccc(F)cc2)c(C(O)=O)c1OC
Show InChI InChI=1S/C16H16FNO5S/c1-3-10-4-9-13(14(16(19)20)15(10)23-2)18-24(21,22)12-7-5-11(17)6-8-12/h4-9,18H,3H2,1-2H3,(H,19,20)
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n/an/a 11n/an/an/an/a7.422



Abbott Laboratories



Assay Description
A coupled enzyme chromogenic assay was developed to measure methionine aminopeptidase-2 activity by monitoring the production of free methionine with...


Bioorg Med Chem Lett 17: 2817-22 (2007)


Article DOI: 10.1016/j.bmcl.2007.02.062
BindingDB Entry DOI: 10.7270/Q2PK0DD1
More data for this
Ligand-Target Pair
Methionine aminopeptidase 2


(Homo sapiens (human))
BDBM17624
PNG
(2-ethoxy-3-ethyl-6-[(4-fluorobenzene)sulfonamido]b...)
Show SMILES CCOc1c(CC)ccc(NS(=O)(=O)c2ccc(F)cc2)c1C(O)=O
Show InChI InChI=1S/C17H18FNO5S/c1-3-11-5-10-14(15(17(20)21)16(11)24-4-2)19-25(22,23)13-8-6-12(18)7-9-13/h5-10,19H,3-4H2,1-2H3,(H,20,21)
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n/an/a 38n/an/an/an/a7.422



Abbott Laboratories



Assay Description
A coupled enzyme chromogenic assay was developed to measure methionine aminopeptidase-2 activity by monitoring the production of free methionine with...


Bioorg Med Chem Lett 17: 2817-22 (2007)


Article DOI: 10.1016/j.bmcl.2007.02.062
BindingDB Entry DOI: 10.7270/Q2PK0DD1
More data for this
Ligand-Target Pair
Methionine aminopeptidase 2


(Homo sapiens (human))
BDBM17625
PNG
(2-(2-aminoethoxy)-3-ethyl-6-[(4-fluorobenzene)sulf...)
Show SMILES CCc1ccc(NS(=O)(=O)c2ccc(F)cc2)c(C(O)=O)c1OCCN
Show InChI InChI=1S/C17H19FN2O5S/c1-2-11-3-8-14(15(17(21)22)16(11)25-10-9-19)20-26(23,24)13-6-4-12(18)5-7-13/h3-8,20H,2,9-10,19H2,1H3,(H,21,22)
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n/an/a 46n/an/an/an/a7.422



Abbott Laboratories



Assay Description
A coupled enzyme chromogenic assay was developed to measure methionine aminopeptidase-2 activity by monitoring the production of free methionine with...


Bioorg Med Chem Lett 17: 2817-22 (2007)


Article DOI: 10.1016/j.bmcl.2007.02.062
BindingDB Entry DOI: 10.7270/Q2PK0DD1
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Methionine aminopeptidase 2


(Homo sapiens (human))
BDBM17626
PNG
(2-(carboxymethoxy)-3-ethyl-6-[(4-fluorobenzene)sul...)
Show SMILES CCc1ccc(NS(=O)(=O)c2ccc(F)cc2)c(C(O)=O)c1OCC(O)=O
Show InChI InChI=1S/C17H16FNO7S/c1-2-10-3-8-13(15(17(22)23)16(10)26-9-14(20)21)19-27(24,25)12-6-4-11(18)5-7-12/h3-8,19H,2,9H2,1H3,(H,20,21)(H,22,23)
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n/an/a 5.80E+3n/an/an/an/a7.422



Abbott Laboratories



Assay Description
A coupled enzyme chromogenic assay was developed to measure methionine aminopeptidase-2 activity by monitoring the production of free methionine with...


Bioorg Med Chem Lett 17: 2817-22 (2007)


Article DOI: 10.1016/j.bmcl.2007.02.062
BindingDB Entry DOI: 10.7270/Q2PK0DD1
More data for this
Ligand-Target Pair
Methionine aminopeptidase 2


(Homo sapiens (human))
BDBM17627
PNG
(2-(2-aminoethoxy)-3-ethyl-6-[(2-propylbenzene)sulf...)
Show SMILES CCCc1ccccc1S(=O)(=O)Nc1ccc(CC)c(OCCN)c1C(O)=O
Show InChI InChI=1S/C20H26N2O5S/c1-3-7-15-8-5-6-9-17(15)28(25,26)22-16-11-10-14(4-2)19(27-13-12-21)18(16)20(23)24/h5-6,8-11,22H,3-4,7,12-13,21H2,1-2H3,(H,23,24)
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n/an/a 16n/an/an/an/a7.422



Abbott Laboratories



Assay Description
A coupled enzyme chromogenic assay was developed to measure methionine aminopeptidase-2 activity by monitoring the production of free methionine with...


Bioorg Med Chem Lett 17: 2817-22 (2007)


Article DOI: 10.1016/j.bmcl.2007.02.062
BindingDB Entry DOI: 10.7270/Q2PK0DD1
More data for this
Ligand-Target Pair
Methionine aminopeptidase 2


(Homo sapiens (human))
BDBM17628
PNG
(3-ethyl-2-methyl-6-(pyridine-2-sulfonamido)benzoic...)
Show SMILES CCc1ccc(NS(=O)(=O)c2ccccn2)c(C(O)=O)c1C
Show InChI InChI=1S/C15H16N2O4S/c1-3-11-7-8-12(14(10(11)2)15(18)19)17-22(20,21)13-6-4-5-9-16-13/h4-9,17H,3H2,1-2H3,(H,18,19)
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n/an/a 67n/an/an/an/a7.422



Abbott Laboratories



Assay Description
A coupled enzyme chromogenic assay was developed to measure methionine aminopeptidase-2 activity by monitoring the production of free methionine with...


Bioorg Med Chem Lett 17: 2817-22 (2007)


Article DOI: 10.1016/j.bmcl.2007.02.062
BindingDB Entry DOI: 10.7270/Q2PK0DD1
More data for this
Ligand-Target Pair
Methionine aminopeptidase 2


(Homo sapiens (human))
BDBM17629
PNG
(2-(2-aminoethoxy)-6-({2-[3-(diethylamino)propyl]-4...)
Show SMILES CCN(CC)CCCc1cc(F)ccc1S(=O)(=O)Nc1ccc(CC)c(OCCN)c1C(O)=O
Show InChI InChI=1S/C24H34FN3O5S/c1-4-17-9-11-20(22(24(29)30)23(17)33-15-13-26)27-34(31,32)21-12-10-19(25)16-18(21)8-7-14-28(5-2)6-3/h9-12,16,27H,4-8,13-15,26H2,1-3H3,(H,29,30)
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n/an/a 24n/an/an/an/a7.422



Abbott Laboratories



Assay Description
A coupled enzyme chromogenic assay was developed to measure methionine aminopeptidase-2 activity by monitoring the production of free methionine with...


Bioorg Med Chem Lett 17: 2817-22 (2007)


Article DOI: 10.1016/j.bmcl.2007.02.062
BindingDB Entry DOI: 10.7270/Q2PK0DD1
More data for this
Ligand-Target Pair
Methionine aminopeptidase 2


(Homo sapiens (human))
BDBM17630
PNG
(5,6-disubstituted anthranilic acid sulfonamide, 19...)
Show SMILES CCc1ccc(NS(=O)(=O)c2ccccc2NCCCCN(C)C)c(C(O)=O)c1OC
Show InChI InChI=1S/C22H31N3O5S/c1-5-16-12-13-18(20(22(26)27)21(16)30-4)24-31(28,29)19-11-7-6-10-17(19)23-14-8-9-15-25(2)3/h6-7,10-13,23-24H,5,8-9,14-15H2,1-4H3,(H,26,27)
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n/an/a 10n/an/an/an/a7.422



Abbott Laboratories



Assay Description
A coupled enzyme chromogenic assay was developed to measure methionine aminopeptidase-2 activity by monitoring the production of free methionine with...


Bioorg Med Chem Lett 17: 2817-22 (2007)


Article DOI: 10.1016/j.bmcl.2007.02.062
BindingDB Entry DOI: 10.7270/Q2PK0DD1
More data for this
Ligand-Target Pair
Methionine aminopeptidase 2


(Homo sapiens (human))
BDBM17631
PNG
(3-ethyl-2-methoxy-6-[(2-{[3-(2-methylpiperidin-1-y...)
Show SMILES CCc1ccc(NS(=O)(=O)c2ccccc2NCCCN2CCCCC2C)c(C(O)=O)c1OC
Show InChI InChI=1S/C25H35N3O5S/c1-4-19-13-14-21(23(25(29)30)24(19)33-3)27-34(31,32)22-12-6-5-11-20(22)26-15-9-17-28-16-8-7-10-18(28)2/h5-6,11-14,18,26-27H,4,7-10,15-17H2,1-3H3,(H,29,30)
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n/an/a 18n/an/an/an/a7.422



Abbott Laboratories



Assay Description
A coupled enzyme chromogenic assay was developed to measure methionine aminopeptidase-2 activity by monitoring the production of free methionine with...


Bioorg Med Chem Lett 17: 2817-22 (2007)


Article DOI: 10.1016/j.bmcl.2007.02.062
BindingDB Entry DOI: 10.7270/Q2PK0DD1
More data for this
Ligand-Target Pair
Methionine aminopeptidase 2


(Homo sapiens (human))
BDBM17632
PNG
(3-ethyl-2-methoxy-6-[(2-{[2-(1-methylpyrrolidin-2-...)
Show SMILES CCc1ccc(NS(=O)(=O)c2ccccc2NCCC2CCCN2C)c(C(O)=O)c1OC
Show InChI InChI=1S/C23H31N3O5S/c1-4-16-11-12-19(21(23(27)28)22(16)31-3)25-32(29,30)20-10-6-5-9-18(20)24-14-13-17-8-7-15-26(17)2/h5-6,9-12,17,24-25H,4,7-8,13-15H2,1-3H3,(H,27,28)
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n/an/a 15n/an/an/an/a7.422



Abbott Laboratories



Assay Description
A coupled enzyme chromogenic assay was developed to measure methionine aminopeptidase-2 activity by monitoring the production of free methionine with...


Bioorg Med Chem Lett 17: 2817-22 (2007)


Article DOI: 10.1016/j.bmcl.2007.02.062
BindingDB Entry DOI: 10.7270/Q2PK0DD1
More data for this
Ligand-Target Pair
Methionine aminopeptidase 2


(Homo sapiens (human))
BDBM17633
PNG
(5,6-disubstituted anthranilic acid sulfonamide, 19...)
Show SMILES CCN(CC)C\C=C/c1cc(F)ccc1S(=O)(=O)Nc1ccc(CC)c(OC)c1C(O)=O
Show InChI InChI=1S/C23H29FN2O5S/c1-5-16-10-12-19(21(23(27)28)22(16)31-4)25-32(29,30)20-13-11-18(24)15-17(20)9-8-14-26(6-2)7-3/h8-13,15,25H,5-7,14H2,1-4H3,(H,27,28)/b9-8-
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n/an/a 26n/an/an/an/a7.422



Abbott Laboratories



Assay Description
A coupled enzyme chromogenic assay was developed to measure methionine aminopeptidase-2 activity by monitoring the production of free methionine with...


Bioorg Med Chem Lett 17: 2817-22 (2007)


Article DOI: 10.1016/j.bmcl.2007.02.062
BindingDB Entry DOI: 10.7270/Q2PK0DD1
More data for this
Ligand-Target Pair
Methionine aminopeptidase 2


(Homo sapiens (human))
BDBM17634
PNG
(5,6-disubstituted anthranilic acid sulfonamide, 19...)
Show SMILES COc1c(ccc(NS(=O)(=O)c2ccc(F)cc2NCCCN(C)C)c1C(O)=O)-c1ccoc1
Show InChI InChI=1S/C23H26FN3O6S/c1-27(2)11-4-10-25-19-13-16(24)5-8-20(19)34(30,31)26-18-7-6-17(15-9-12-33-14-15)22(32-3)21(18)23(28)29/h5-9,12-14,25-26H,4,10-11H2,1-3H3,(H,28,29)
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n/an/a 17n/an/an/an/a7.422



Abbott Laboratories



Assay Description
A coupled enzyme chromogenic assay was developed to measure methionine aminopeptidase-2 activity by monitoring the production of free methionine with...


Bioorg Med Chem Lett 17: 2817-22 (2007)


Article DOI: 10.1016/j.bmcl.2007.02.062
BindingDB Entry DOI: 10.7270/Q2PK0DD1
More data for this
Ligand-Target Pair
Methionine aminopeptidase 2


(Homo sapiens (human))
BDBM17635
PNG
(5,6-disubstituted anthranilic acid sulfonamide, 19...)
Show SMILES CCN(CC)C\C=C/c1cc(F)ccc1S(=O)(=O)Nc1ccc(-c2ccoc2)c(OC)c1C(O)=O
Show InChI InChI=1S/C25H27FN2O6S/c1-4-28(5-2)13-6-7-17-15-19(26)8-11-22(17)35(31,32)27-21-10-9-20(18-12-14-34-16-18)24(33-3)23(21)25(29)30/h6-12,14-16,27H,4-5,13H2,1-3H3,(H,29,30)/b7-6-
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n/an/a 15n/an/an/an/a7.422



Abbott Laboratories



Assay Description
A coupled enzyme chromogenic assay was developed to measure methionine aminopeptidase-2 activity by monitoring the production of free methionine with...


Bioorg Med Chem Lett 17: 2817-22 (2007)


Article DOI: 10.1016/j.bmcl.2007.02.062
BindingDB Entry DOI: 10.7270/Q2PK0DD1
More data for this
Ligand-Target Pair
Methionine aminopeptidase 2


(Homo sapiens (human))
BDBM17477
PNG
(2-benzenesulfonamido-5-methylbenzoic acid | A44414...)
Show SMILES Cc1ccc(NS(=O)(=O)c2ccccc2)c(c1)C(O)=O
Show InChI InChI=1S/C14H13NO4S/c1-10-7-8-13(12(9-10)14(16)17)15-20(18,19)11-5-3-2-4-6-11/h2-9,15H,1H3,(H,16,17)
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n/an/a 1.40E+3n/an/an/an/a7.422



Abbott Laboratories



Assay Description
A coupled enzyme chromogenic assay was developed to measure methionine aminopeptidase-2 activity by monitoring the production of free methionine with...


J Med Chem 49: 3832-49 (2006)


Article DOI: 10.1021/jm0601001
BindingDB Entry DOI: 10.7270/Q22V2DDZ
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Methionine aminopeptidase 2


(Homo sapiens (human))
BDBM17478
PNG
(2-benzenesulfonamido-5,6,7,8-tetrahydronaphthalene...)
Show SMILES OC(=O)c1c(NS(=O)(=O)c2ccccc2)ccc2CCCCc12
Show InChI InChI=1S/C17H17NO4S/c19-17(20)16-14-9-5-4-6-12(14)10-11-15(16)18-23(21,22)13-7-2-1-3-8-13/h1-3,7-8,10-11,18H,4-6,9H2,(H,19,20)
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n/an/a 10n/an/an/an/a7.422



Abbott Laboratories



Assay Description
A coupled enzyme chromogenic assay was developed to measure methionine aminopeptidase-2 activity by monitoring the production of free methionine with...


J Med Chem 49: 3832-49 (2006)


Article DOI: 10.1021/jm0601001
BindingDB Entry DOI: 10.7270/Q22V2DDZ
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Methionine aminopeptidase 2


(Homo sapiens (human))
BDBM17479
PNG
(2-[(2-{[2-(dimethylamino)ethyl]amino}benzene)sulfo...)
Show SMILES CN(C)CCNc1ccccc1S(=O)(=O)Nc1ccc2CCCCc2c1C(O)=O
Show InChI InChI=1S/C21H27N3O4S/c1-24(2)14-13-22-17-9-5-6-10-19(17)29(27,28)23-18-12-11-15-7-3-4-8-16(15)20(18)21(25)26/h5-6,9-12,22-23H,3-4,7-8,13-14H2,1-2H3,(H,25,26)
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n/an/a 48n/an/an/an/a7.422



Abbott Laboratories



Assay Description
A coupled enzyme chromogenic assay was developed to measure methionine aminopeptidase-2 activity by monitoring the production of free methionine with...


J Med Chem 49: 3832-49 (2006)


Article DOI: 10.1021/jm0601001
BindingDB Entry DOI: 10.7270/Q22V2DDZ
More data for this
Ligand-Target Pair
Methionine aminopeptidase 2


(Homo sapiens (human))
BDBM17480
PNG
(2-[(2-{[2-(diethylamino)ethyl]amino}benzene)sulfon...)
Show SMILES CCN(CC)CCNc1ccccc1S(=O)(=O)Nc1ccc2CCCCc2c1C(O)=O
Show InChI InChI=1S/C23H31N3O4S/c1-3-26(4-2)16-15-24-19-11-7-8-12-21(19)31(29,30)25-20-14-13-17-9-5-6-10-18(17)22(20)23(27)28/h7-8,11-14,24-25H,3-6,9-10,15-16H2,1-2H3,(H,27,28)
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n/an/a 31n/an/an/an/a7.422



Abbott Laboratories



Assay Description
A coupled enzyme chromogenic assay was developed to measure methionine aminopeptidase-2 activity by monitoring the production of free methionine with...


J Med Chem 49: 3832-49 (2006)


Article DOI: 10.1021/jm0601001
BindingDB Entry DOI: 10.7270/Q22V2DDZ
More data for this
Ligand-Target Pair
Methionine aminopeptidase 2


(Homo sapiens (human))
BDBM17481
PNG
(2-{[2-({2-[bis(propan-2-yl)amino]ethyl}amino)benze...)
Show SMILES CC(C)N(CCNc1ccccc1S(=O)(=O)Nc1ccc2CCCCc2c1C(O)=O)C(C)C
Show InChI InChI=1S/C25H35N3O4S/c1-17(2)28(18(3)4)16-15-26-21-11-7-8-12-23(21)33(31,32)27-22-14-13-19-9-5-6-10-20(19)24(22)25(29)30/h7-8,11-14,17-18,26-27H,5-6,9-10,15-16H2,1-4H3,(H,29,30)
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n/an/a 31n/an/an/an/a7.422



Abbott Laboratories



Assay Description
A coupled enzyme chromogenic assay was developed to measure methionine aminopeptidase-2 activity by monitoring the production of free methionine with...


J Med Chem 49: 3832-49 (2006)


Article DOI: 10.1021/jm0601001
BindingDB Entry DOI: 10.7270/Q22V2DDZ
More data for this
Ligand-Target Pair
Methionine aminopeptidase 2


(Homo sapiens (human))
BDBM17482
PNG
(2-[(2-{[2-(pyrrolidin-1-yl)ethyl]amino}benzene)sul...)
Show SMILES OC(=O)c1c(NS(=O)(=O)c2ccccc2NCCN2CCCC2)ccc2CCCCc12
Show InChI InChI=1S/C23H29N3O4S/c27-23(28)22-18-8-2-1-7-17(18)11-12-20(22)25-31(29,30)21-10-4-3-9-19(21)24-13-16-26-14-5-6-15-26/h3-4,9-12,24-25H,1-2,5-8,13-16H2,(H,27,28)
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n/an/a 69n/an/an/an/a7.422



Abbott Laboratories



Assay Description
A coupled enzyme chromogenic assay was developed to measure methionine aminopeptidase-2 activity by monitoring the production of free methionine with...


J Med Chem 49: 3832-49 (2006)


Article DOI: 10.1021/jm0601001
BindingDB Entry DOI: 10.7270/Q22V2DDZ
More data for this
Ligand-Target Pair
Methionine aminopeptidase 2


(Homo sapiens (human))
BDBM17483
PNG
(2-[(2-{[3-(dimethylamino)propyl]amino}benzene)sulf...)
Show SMILES CN(C)CCCNc1ccccc1S(=O)(=O)Nc1ccc2CCCCc2c1C(O)=O
Show InChI InChI=1S/C22H29N3O4S/c1-25(2)15-7-14-23-18-10-5-6-11-20(18)30(28,29)24-19-13-12-16-8-3-4-9-17(16)21(19)22(26)27/h5-6,10-13,23-24H,3-4,7-9,14-15H2,1-2H3,(H,26,27)
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n/an/a 14n/an/an/an/a7.422



Abbott Laboratories



Assay Description
A coupled enzyme chromogenic assay was developed to measure methionine aminopeptidase-2 activity by monitoring the production of free methionine with...


J Med Chem 49: 3832-49 (2006)


Article DOI: 10.1021/jm0601001
BindingDB Entry DOI: 10.7270/Q22V2DDZ
More data for this
Ligand-Target Pair
Methionine aminopeptidase 2


(Homo sapiens (human))
BDBM17484
PNG
(2-[(2-{[3-(diethylamino)propyl]amino}benzene)sulfo...)
Show SMILES CCN(CC)CCCNc1ccccc1S(=O)(=O)Nc1ccc2CCCCc2c1C(O)=O
Show InChI InChI=1S/C24H33N3O4S/c1-3-27(4-2)17-9-16-25-20-12-7-8-13-22(20)32(30,31)26-21-15-14-18-10-5-6-11-19(18)23(21)24(28)29/h7-8,12-15,25-26H,3-6,9-11,16-17H2,1-2H3,(H,28,29)
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n/an/a 25n/an/an/an/a7.422



Abbott Laboratories



Assay Description
A coupled enzyme chromogenic assay was developed to measure methionine aminopeptidase-2 activity by monitoring the production of free methionine with...


J Med Chem 49: 3832-49 (2006)


Article DOI: 10.1021/jm0601001
BindingDB Entry DOI: 10.7270/Q22V2DDZ
More data for this
Ligand-Target Pair
Methionine aminopeptidase 2


(Homo sapiens (human))
BDBM17485
PNG
(2-[(2-{[3-(dibutylamino)propyl]amino}benzene)sulfo...)
Show SMILES CCCCN(CCCC)CCCNc1ccccc1S(=O)(=O)Nc1ccc2CCCCc2c1C(O)=O
Show InChI InChI=1S/C28H41N3O4S/c1-3-5-19-31(20-6-4-2)21-11-18-29-24-14-9-10-15-26(24)36(34,35)30-25-17-16-22-12-7-8-13-23(22)27(25)28(32)33/h9-10,14-17,29-30H,3-8,11-13,18-21H2,1-2H3,(H,32,33)
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n/an/a 52n/an/an/an/a7.422



Abbott Laboratories



Assay Description
A coupled enzyme chromogenic assay was developed to measure methionine aminopeptidase-2 activity by monitoring the production of free methionine with...


J Med Chem 49: 3832-49 (2006)


Article DOI: 10.1021/jm0601001
BindingDB Entry DOI: 10.7270/Q22V2DDZ
More data for this
Ligand-Target Pair
Methionine aminopeptidase 2


(Homo sapiens (human))
BDBM17486
PNG
(2-{[2-({2-[(dimethylamino)methyl]-2-methylpropyl}a...)
Show SMILES CN(C)CC(C)(C)CNc1ccccc1S(=O)(=O)Nc1ccc2CCCCc2c1C(O)=O
Show InChI InChI=1S/C24H33N3O4S/c1-24(2,16-27(3)4)15-25-19-11-7-8-12-21(19)32(30,31)26-20-14-13-17-9-5-6-10-18(17)22(20)23(28)29/h7-8,11-14,25-26H,5-6,9-10,15-16H2,1-4H3,(H,28,29)
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n/an/a 18n/an/an/an/a7.422



Abbott Laboratories



Assay Description
A coupled enzyme chromogenic assay was developed to measure methionine aminopeptidase-2 activity by monitoring the production of free methionine with...


J Med Chem 49: 3832-49 (2006)


Article DOI: 10.1021/jm0601001
BindingDB Entry DOI: 10.7270/Q22V2DDZ
More data for this
Ligand-Target Pair
Methionine aminopeptidase 2


(Homo sapiens (human))
BDBM17487
PNG
(2-{[2-({3-[bis(2-hydroxyethyl)amino]propyl}amino)b...)
Show SMILES OCCN(CCO)CCCNc1ccccc1S(=O)(=O)Nc1ccc2CCCCc2c1C(O)=O
Show InChI InChI=1S/C24H33N3O6S/c28-16-14-27(15-17-29)13-5-12-25-20-8-3-4-9-22(20)34(32,33)26-21-11-10-18-6-1-2-7-19(18)23(21)24(30)31/h3-4,8-11,25-26,28-29H,1-2,5-7,12-17H2,(H,30,31)
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n/an/a 26n/an/an/an/a7.422



Abbott Laboratories



Assay Description
A coupled enzyme chromogenic assay was developed to measure methionine aminopeptidase-2 activity by monitoring the production of free methionine with...


J Med Chem 49: 3832-49 (2006)


Article DOI: 10.1021/jm0601001
BindingDB Entry DOI: 10.7270/Q22V2DDZ
More data for this
Ligand-Target Pair
Methionine aminopeptidase 2


(Homo sapiens (human))
BDBM17488
PNG
(2-[(2-{[3-(ethylamino)propyl]amino}benzene)sulfona...)
Show SMILES CCNCCCNc1ccccc1S(=O)(=O)Nc1ccc2CCCCc2c1C(O)=O
Show InChI InChI=1S/C22H29N3O4S/c1-2-23-14-7-15-24-18-10-5-6-11-20(18)30(28,29)25-19-13-12-16-8-3-4-9-17(16)21(19)22(26)27/h5-6,10-13,23-25H,2-4,7-9,14-15H2,1H3,(H,26,27)
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n/an/a 12n/an/an/an/a7.422



Abbott Laboratories



Assay Description
A coupled enzyme chromogenic assay was developed to measure methionine aminopeptidase-2 activity by monitoring the production of free methionine with...


J Med Chem 49: 3832-49 (2006)


Article DOI: 10.1021/jm0601001
BindingDB Entry DOI: 10.7270/Q22V2DDZ
More data for this
Ligand-Target Pair
Methionine aminopeptidase 2


(Homo sapiens (human))
BDBM17489
PNG
(2-{[2-({3-[(2-hydroxyethyl)amino]propyl}amino)benz...)
Show SMILES OCCNCCCNc1ccccc1S(=O)(=O)Nc1ccc2CCCCc2c1C(O)=O
Show InChI InChI=1S/C22H29N3O5S/c26-15-14-23-12-5-13-24-18-8-3-4-9-20(18)31(29,30)25-19-11-10-16-6-1-2-7-17(16)21(19)22(27)28/h3-4,8-11,23-26H,1-2,5-7,12-15H2,(H,27,28)
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n/an/a 15n/an/an/an/a7.422



Abbott Laboratories



Assay Description
A coupled enzyme chromogenic assay was developed to measure methionine aminopeptidase-2 activity by monitoring the production of free methionine with...


J Med Chem 49: 3832-49 (2006)


Article DOI: 10.1021/jm0601001
BindingDB Entry DOI: 10.7270/Q22V2DDZ
More data for this
Ligand-Target Pair
Methionine aminopeptidase 2


(Homo sapiens (human))
BDBM17490
PNG
(2-({2-[(3-{[(tert-butoxy)carbonyl]amino}propyl)ami...)
Show SMILES CC(C)(C)OC(=O)NCCCNc1ccccc1S(=O)(=O)Nc1ccc2CCCCc2c1C(O)=O
Show InChI InChI=1S/C25H33N3O6S/c1-25(2,3)34-24(31)27-16-8-15-26-19-11-6-7-12-21(19)35(32,33)28-20-14-13-17-9-4-5-10-18(17)22(20)23(29)30/h6-7,11-14,26,28H,4-5,8-10,15-16H2,1-3H3,(H,27,31)(H,29,30)
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n/an/a 77n/an/an/an/a7.422



Abbott Laboratories



Assay Description
A coupled enzyme chromogenic assay was developed to measure methionine aminopeptidase-2 activity by monitoring the production of free methionine with...


J Med Chem 49: 3832-49 (2006)


Article DOI: 10.1021/jm0601001
BindingDB Entry DOI: 10.7270/Q22V2DDZ
More data for this
Ligand-Target Pair
Methionine aminopeptidase 2


(Homo sapiens (human))
BDBM17491
PNG
(2-({2-[(3-{[(tert-butoxy)carbonyl](methyl)amino}pr...)
Show SMILES CN(CCCNc1ccccc1S(=O)(=O)Nc1ccc2CCCCc2c1C(O)=O)C(=O)OC(C)(C)C
Show InChI InChI=1S/C26H35N3O6S/c1-26(2,3)35-25(32)29(4)17-9-16-27-20-12-7-8-13-22(20)36(33,34)28-21-15-14-18-10-5-6-11-19(18)23(21)24(30)31/h7-8,12-15,27-28H,5-6,9-11,16-17H2,1-4H3,(H,30,31)
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n/an/a 110n/an/an/an/a7.422



Abbott Laboratories



Assay Description
A coupled enzyme chromogenic assay was developed to measure methionine aminopeptidase-2 activity by monitoring the production of free methionine with...


J Med Chem 49: 3832-49 (2006)


Article DOI: 10.1021/jm0601001
BindingDB Entry DOI: 10.7270/Q22V2DDZ
More data for this
Ligand-Target Pair
Methionine aminopeptidase 2


(Homo sapiens (human))
BDBM17492
PNG
(2-({2-[(3-aminopropyl)amino]benzene}sulfonamido)-5...)
Show SMILES NCCCNc1ccccc1S(=O)(=O)Nc1ccc2CCCCc2c1C(O)=O
Show InChI InChI=1S/C20H25N3O4S/c21-12-5-13-22-16-8-3-4-9-18(16)28(26,27)23-17-11-10-14-6-1-2-7-15(14)19(17)20(24)25/h3-4,8-11,22-23H,1-2,5-7,12-13,21H2,(H,24,25)
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n/an/a 13n/an/an/an/a7.422



Abbott Laboratories



Assay Description
A coupled enzyme chromogenic assay was developed to measure methionine aminopeptidase-2 activity by monitoring the production of free methionine with...


J Med Chem 49: 3832-49 (2006)


Article DOI: 10.1021/jm0601001
BindingDB Entry DOI: 10.7270/Q22V2DDZ
More data for this
Ligand-Target Pair
Methionine aminopeptidase 2


(Homo sapiens (human))
BDBM17493
PNG
(2-[(2-{[3-(4-methylpiperazin-1-yl)propyl]amino}ben...)
Show SMILES CN1CCN(CCCNc2ccccc2S(=O)(=O)Nc2ccc3CCCCc3c2C(O)=O)CC1
Show InChI InChI=1S/C25H34N4O4S/c1-28-15-17-29(18-16-28)14-6-13-26-21-9-4-5-10-23(21)34(32,33)27-22-12-11-19-7-2-3-8-20(19)24(22)25(30)31/h4-5,9-12,26-27H,2-3,6-8,13-18H2,1H3,(H,30,31)
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Abbott Laboratories



Assay Description
A coupled enzyme chromogenic assay was developed to measure methionine aminopeptidase-2 activity by monitoring the production of free methionine with...


J Med Chem 49: 3832-49 (2006)


Article DOI: 10.1021/jm0601001
BindingDB Entry DOI: 10.7270/Q22V2DDZ
More data for this
Ligand-Target Pair
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