Compile Data Set for Download or QSAR

Found 29 hits of ph data with Target = 'Monoamine Oxidase Type B (MAO-B)'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Monoamine Oxidase Type B (MAO-B) (Bos taurus)	BDBM11014 ((-)-(S)1 | (5S)-5-(4-chlorophenyl)-3-(4-methylphen...) Show SMILES Cc1ccc(cc1)C1=NN([C@@H](C1)c1ccc(Cl)cc1)C(N)=S Show InChI InChI=1S/C17H16ClN3S/c1-11-2-4-12(5-3-11)15-10-16(21(20-15)17(19)22)13-6-8-14(18)9-7-13/h2-9,16H,10H2,1H3,(H2,19,22)/t16-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	1	-53.6	n/a	n/a	n/a	n/a	n/a	7.4	38
Universita degli Studi di Roma La Sapienza					Assay Description MAO A and MAO B activities were determined spectrophotometrically using kynuramine as substrates. Fluorimetric measurements were recorded with a Perk...				J Med Chem 48: 7113-22 (2005) Article DOI: 10.1021/jm040903t BindingDB Entry DOI: 10.7270/Q2JH3JDW
					More data for this Ligand-Target Pair
Monoamine Oxidase Type B (MAO-B) (Bos taurus)	BDBM11004 (1-thiocarbamoyl-3,5-diaryl-4,5-dihydro-(1H)-pyrazo...) Show SMILES Cc1ccc(cc1)C1=NN(C(C1)c1ccc(Cl)cc1)C(N)=S Show InChI InChI=1S/C17H16ClN3S/c1-11-2-4-12(5-3-11)15-10-16(21(20-15)17(19)22)13-6-8-14(18)9-7-13/h2-9,16H,10H2,1H3,(H2,19,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	1.5	-52.6	n/a	n/a	n/a	n/a	n/a	7.4	38
Universita degli Studi di Roma La Sapienza					Assay Description MAO A and MAO B activities were determined spectrophotometrically using kynuramine as substrates. Fluorimetric measurements were recorded with a Perk...				J Med Chem 48: 7113-22 (2005) Article DOI: 10.1021/jm040903t BindingDB Entry DOI: 10.7270/Q2JH3JDW
					More data for this Ligand-Target Pair
Monoamine Oxidase Type B (MAO-B) (Bos taurus)	BDBM11015 ((+)-(R)1 | (5R)-5-(4-chlorophenyl)-3-(4-methylphen...) Show SMILES Cc1ccc(cc1)C1=NN([C@H](C1)c1ccc(Cl)cc1)C(N)=S Show InChI InChI=1S/C17H16ClN3S/c1-11-2-4-12(5-3-11)15-10-16(21(20-15)17(19)22)13-6-8-14(18)9-7-13/h2-9,16H,10H2,1H3,(H2,19,22)/t16-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	2.70	-51.0	n/a	n/a	n/a	n/a	n/a	7.4	38
Universita degli Studi di Roma La Sapienza					Assay Description MAO A and MAO B activities were determined spectrophotometrically using kynuramine as substrates. Fluorimetric measurements were recorded with a Perk...				J Med Chem 48: 7113-22 (2005) Article DOI: 10.1021/jm040903t BindingDB Entry DOI: 10.7270/Q2JH3JDW
					More data for this Ligand-Target Pair
Monoamine Oxidase Type B (MAO-B) (Bos taurus)	BDBM11010 (1-thiocarbamoyl-3,5-diaryl-4,5-dihydro-(1H)-pyrazo...) Show SMILES NC(=S)N1N=C(CC1c1ccc(Cl)cc1)c1cccs1 Show InChI InChI=1S/C14H12ClN3S2/c15-10-5-3-9(4-6-10)12-8-11(13-2-1-7-20-13)17-18(12)14(16)19/h1-7,12H,8H2,(H2,16,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	6	-49.0	n/a	n/a	n/a	n/a	n/a	7.4	38
Universita degli Studi di Roma La Sapienza					Assay Description MAO A and MAO B activities were determined spectrophotometrically using kynuramine as substrates. Fluorimetric measurements were recorded with a Perk...				J Med Chem 48: 7113-22 (2005) Article DOI: 10.1021/jm040903t BindingDB Entry DOI: 10.7270/Q2JH3JDW
					More data for this Ligand-Target Pair
Monoamine Oxidase Type B (MAO-B) (Bos taurus)	BDBM11005 (1-thiocarbamoyl-3,5-diaryl-4,5-dihydro-(1H)-pyrazo...) Show SMILES Cc1ccc(cc1)C1CC(=NN1C(N)=S)c1ccc(C)cc1 Show InChI InChI=1S/C18H19N3S/c1-12-3-7-14(8-4-12)16-11-17(21(20-16)18(19)22)15-9-5-13(2)6-10-15/h3-10,17H,11H2,1-2H3,(H2,19,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	10	-47.7	n/a	n/a	n/a	n/a	n/a	7.4	38
Universita degli Studi di Roma La Sapienza					Assay Description MAO A and MAO B activities were determined spectrophotometrically using kynuramine as substrates. Fluorimetric measurements were recorded with a Perk...				J Med Chem 48: 7113-22 (2005) Article DOI: 10.1021/jm040903t BindingDB Entry DOI: 10.7270/Q2JH3JDW
					More data for this Ligand-Target Pair
Monoamine Oxidase Type B (MAO-B) (Bos taurus)	BDBM11011 (1-thiocarbamoyl-3,5-diaryl-4,5-dihydro-(1H)-pyrazo...) Show SMILES Cc1ccc(cc1)C1CC(=NN1C(N)=S)c1cccs1 Show InChI InChI=1S/C15H15N3S2/c1-10-4-6-11(7-5-10)13-9-12(14-3-2-8-20-14)17-18(13)15(16)19/h2-8,13H,9H2,1H3,(H2,16,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	10	-47.7	n/a	n/a	n/a	n/a	n/a	7.4	38
Universita degli Studi di Roma La Sapienza					Assay Description MAO A and MAO B activities were determined spectrophotometrically using kynuramine as substrates. Fluorimetric measurements were recorded with a Perk...				J Med Chem 48: 7113-22 (2005) Article DOI: 10.1021/jm040903t BindingDB Entry DOI: 10.7270/Q2JH3JDW
					More data for this Ligand-Target Pair
Monoamine Oxidase Type B (MAO-B) (Bos taurus)	BDBM11012 (1-thiocarbamoyl-3,5-diaryl-4,5-dihydro-(1H)-pyrazo...) Show SMILES NC(=S)N1N=C(CC1c1ccco1)c1cccs1 Show InChI InChI=1S/C12H11N3OS2/c13-12(17)15-9(10-3-1-5-16-10)7-8(14-15)11-4-2-6-18-11/h1-6,9H,7H2,(H2,13,17)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	20	-45.9	n/a	n/a	n/a	n/a	n/a	7.4	38
Universita degli Studi di Roma La Sapienza					Assay Description MAO A and MAO B activities were determined spectrophotometrically using kynuramine as substrates. Fluorimetric measurements were recorded with a Perk...				J Med Chem 48: 7113-22 (2005) Article DOI: 10.1021/jm040903t BindingDB Entry DOI: 10.7270/Q2JH3JDW
					More data for this Ligand-Target Pair
Monoamine Oxidase Type B (MAO-B) (Bos taurus)	BDBM11013 (1-thiocarbamoyl-3,5-diaryl-4,5-dihydro-(1H)-pyrazo...) Show SMILES NC(=S)N1N=C(CC1c1cccs1)c1cccs1 Show InChI InChI=1S/C12H11N3S3/c13-12(16)15-9(11-4-2-6-18-11)7-8(14-15)10-3-1-5-17-10/h1-6,9H,7H2,(H2,13,16)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	50	-43.5	n/a	n/a	n/a	n/a	n/a	7.4	38
Universita degli Studi di Roma La Sapienza					Assay Description MAO A and MAO B activities were determined spectrophotometrically using kynuramine as substrates. Fluorimetric measurements were recorded with a Perk...				J Med Chem 48: 7113-22 (2005) Article DOI: 10.1021/jm040903t BindingDB Entry DOI: 10.7270/Q2JH3JDW
					More data for this Ligand-Target Pair
Monoamine Oxidase Type B (MAO-B) (Bos taurus)	BDBM11008 (1-thiocarbamoyl-3,5-diaryl-4,5-dihydro-(1H)-pyrazo...) Show SMILES Cc1ccc(cc1)C1CC(=NN1C(N)=S)c1ccc(F)cc1 Show InChI InChI=1S/C17H16FN3S/c1-11-2-4-13(5-3-11)16-10-15(20-21(16)17(19)22)12-6-8-14(18)9-7-12/h2-9,16H,10H2,1H3,(H2,19,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	50	-43.5	n/a	n/a	n/a	n/a	n/a	7.4	38
Universita degli Studi di Roma La Sapienza					Assay Description MAO A and MAO B activities were determined spectrophotometrically using kynuramine as substrates. Fluorimetric measurements were recorded with a Perk...				J Med Chem 48: 7113-22 (2005) Article DOI: 10.1021/jm040903t BindingDB Entry DOI: 10.7270/Q2JH3JDW
					More data for this Ligand-Target Pair
Monoamine Oxidase Type B (MAO-B) (Bos taurus)	BDBM11006 (1-thiocarbamoyl-3,5-diaryl-4,5-dihydro-(1H)-pyrazo...) Show SMILES Cc1ccc(cc1)C1=NN(C(C1)c1ccco1)C(N)=S Show InChI InChI=1S/C15H15N3OS/c1-10-4-6-11(7-5-10)12-9-13(14-3-2-8-19-14)18(17-12)15(16)20/h2-8,13H,9H2,1H3,(H2,16,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	170	-40.3	n/a	n/a	n/a	n/a	n/a	7.4	38
Universita degli Studi di Roma La Sapienza					Assay Description MAO A and MAO B activities were determined spectrophotometrically using kynuramine as substrates. Fluorimetric measurements were recorded with a Perk...				J Med Chem 48: 7113-22 (2005) Article DOI: 10.1021/jm040903t BindingDB Entry DOI: 10.7270/Q2JH3JDW
					More data for this Ligand-Target Pair
Monoamine Oxidase Type B (MAO-B) (Mus musculus)	BDBM11018 (2-[(E)-2-(3-chlorophenyl)ethenyl]-3,5,7-trimethyl-...) Show SMILES CC1c2nc(\C=C\c3cccc(Cl)c3)n(C)c2C(=O)N(C)C1=O Show InChI InChI=1S/C17H16ClN3O2/c1-10-14-15(17(23)21(3)16(10)22)20(2)13(19-14)8-7-11-5-4-6-12(18)9-11/h4-10H,1-3H3/b8-7+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	200	-38.2	n/a	n/a	n/a	n/a	n/a	7.4	25
Emory University					Assay Description MAO A and MAO B activities were determined spectrophotometrically. Competitive Ki values for both enzymes were determined by measuring initial rates ...				J Biol Chem 280: 15761-6 (2005) Article DOI: 10.1074/jbc.M500949200 BindingDB Entry DOI: 10.7270/Q2DR2SP5
					More data for this Ligand-Target Pair
Monoamine Oxidase Type B (MAO-B) (Bos taurus)	BDBM11009 (1-thiocarbamoyl-3,5-diaryl-4,5-dihydro-(1H)-pyrazo...) Show SMILES NC(=S)N1N=C(CC1c1ccco1)c1ccc(F)cc1 Show InChI InChI=1S/C14H12FN3OS/c15-10-5-3-9(4-6-10)11-8-12(13-2-1-7-19-13)18(17-11)14(16)20/h1-7,12H,8H2,(H2,16,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	370	-38.3	n/a	n/a	n/a	n/a	n/a	7.4	38
Universita degli Studi di Roma La Sapienza					Assay Description MAO A and MAO B activities were determined spectrophotometrically using kynuramine as substrates. Fluorimetric measurements were recorded with a Perk...				J Med Chem 48: 7113-22 (2005) Article DOI: 10.1021/jm040903t BindingDB Entry DOI: 10.7270/Q2JH3JDW
					More data for this Ligand-Target Pair
Monoamine Oxidase Type B (MAO-B) (Bos taurus)	BDBM11007 (1-thiocarbamoyl-3,5-diaryl-4,5-dihydro-(1H)-pyrazo...) Show SMILES NC(=S)N1N=C(CC1c1ccc(Cl)cc1)c1ccc(F)cc1 Show InChI InChI=1S/C16H13ClFN3S/c17-12-5-1-11(2-6-12)15-9-14(20-21(15)16(19)22)10-3-7-13(18)8-4-10/h1-8,15H,9H2,(H2,19,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	1.00E+3	-35.7	n/a	n/a	n/a	n/a	n/a	7.4	38
Universita degli Studi di Roma La Sapienza					Assay Description MAO A and MAO B activities were determined spectrophotometrically using kynuramine as substrates. Fluorimetric measurements were recorded with a Perk...				J Med Chem 48: 7113-22 (2005) Article DOI: 10.1021/jm040903t BindingDB Entry DOI: 10.7270/Q2JH3JDW
					More data for this Ligand-Target Pair
Monoamine Oxidase Type B (MAO-B) (Rattus norvegicus (rat))	BDBM11018 (2-[(E)-2-(3-chlorophenyl)ethenyl]-3,5,7-trimethyl-...) Show SMILES CC1c2nc(\C=C\c3cccc(Cl)c3)n(C)c2C(=O)N(C)C1=O Show InChI InChI=1S/C17H16ClN3O2/c1-10-14-15(17(23)21(3)16(10)22)20(2)13(19-14)8-7-11-5-4-6-12(18)9-11/h4-10H,1-3H3/b8-7+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.10E+3	-34.0	n/a	n/a	n/a	n/a	n/a	7.4	25
Emory University					Assay Description MAO A and MAO B activities were determined spectrophotometrically. Competitive Ki values for both enzymes were determined by measuring initial rates ...				J Biol Chem 280: 15761-6 (2005) Article DOI: 10.1074/jbc.M500949200 BindingDB Entry DOI: 10.7270/Q2DR2SP5
					More data for this Ligand-Target Pair
Monoamine Oxidase Type B (MAO-B) (Bos taurus)	BDBM11017 ((+)-(R)4 | (5R)-5-(4-chlorophenyl)-3-(4-fluorophen...) Show SMILES NC(=S)N1N=C(C[C@@H]1c1ccc(Cl)cc1)c1ccc(F)cc1 Show InChI InChI=1S/C16H13ClFN3S/c17-12-5-1-11(2-6-12)15-9-14(20-21(15)16(19)22)10-3-7-13(18)8-4-10/h1-8,15H,9H2,(H2,19,22)/t15-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	1.40E+3	-34.9	n/a	n/a	n/a	n/a	n/a	7.4	38
Universita degli Studi di Roma La Sapienza					Assay Description MAO A and MAO B activities were determined spectrophotometrically using kynuramine as substrates. Fluorimetric measurements were recorded with a Perk...				J Med Chem 48: 7113-22 (2005) Article DOI: 10.1021/jm040903t BindingDB Entry DOI: 10.7270/Q2JH3JDW
					More data for this Ligand-Target Pair
Monoamine Oxidase Type B (MAO-B) (Equus caballus (horse))	BDBM11018 (2-[(E)-2-(3-chlorophenyl)ethenyl]-3,5,7-trimethyl-...) Show SMILES CC1c2nc(\C=C\c3cccc(Cl)c3)n(C)c2C(=O)N(C)C1=O Show InChI InChI=1S/C17H16ClN3O2/c1-10-14-15(17(23)21(3)16(10)22)20(2)13(19-14)8-7-11-5-4-6-12(18)9-11/h4-10H,1-3H3/b8-7+	PDB GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.40E+3	-33.4	n/a	n/a	n/a	n/a	n/a	7.4	25
Emory University					Assay Description MAO A and MAO B activities were determined spectrophotometrically. Competitive Ki values for both enzymes were determined by measuring initial rates ...				J Biol Chem 280: 15761-6 (2005) Article DOI: 10.1074/jbc.M500949200 BindingDB Entry DOI: 10.7270/Q2DR2SP5
					More data for this Ligand-Target Pair
Monoamine Oxidase Type B (MAO-B) (Mus musculus)	BDBM11021 ((2E,6E)-3,7,11-trimethyldodeca-2,6,10-trien-1-ol |...) Show SMILES CC(C)=CCC\C(C)=C\CC\C(C)=C\CO Show InChI InChI=1S/C15H26O/c1-13(2)7-5-8-14(3)9-6-10-15(4)11-12-16/h7,9,11,16H,5-6,8,10,12H2,1-4H3/b14-9+,15-11+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	MMDB PDB Article PubMed	2.40E+3	-32.1	n/a	n/a	n/a	n/a	n/a	7.4	25
Emory University					Assay Description MAO A and MAO B activities were determined spectrophotometrically. Competitive Ki values for both enzymes were determined by measuring initial rates ...				J Biol Chem 280: 15761-6 (2005) Article DOI: 10.1074/jbc.M500949200 BindingDB Entry DOI: 10.7270/Q2DR2SP5
					More data for this Ligand-Target Pair				3D Structure (crystal)
Monoamine Oxidase Type B (MAO-B) (Bos taurus)	BDBM11016 ((-)-(S)4 | (5S)-5-(4-chlorophenyl)-3-(4-fluorophen...) Show SMILES NC(=S)N1N=C(C[C@H]1c1ccc(Cl)cc1)c1ccc(F)cc1 Show InChI InChI=1S/C16H13ClFN3S/c17-12-5-1-11(2-6-12)15-9-14(20-21(15)16(19)22)10-3-7-13(18)8-4-10/h1-8,15H,9H2,(H2,19,22)/t15-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	2.40E+3	-33.5	n/a	n/a	n/a	n/a	n/a	7.4	38
Universita degli Studi di Roma La Sapienza					Assay Description MAO A and MAO B activities were determined spectrophotometrically using kynuramine as substrates. Fluorimetric measurements were recorded with a Perk...				J Med Chem 48: 7113-22 (2005) Article DOI: 10.1021/jm040903t BindingDB Entry DOI: 10.7270/Q2JH3JDW
					More data for this Ligand-Target Pair
Monoamine Oxidase Type B (MAO-B) (Rattus norvegicus (rat))	BDBM11021 ((2E,6E)-3,7,11-trimethyldodeca-2,6,10-trien-1-ol |...) Show SMILES CC(C)=CCC\C(C)=C\CC\C(C)=C\CO Show InChI InChI=1S/C15H26O/c1-13(2)7-5-8-14(3)9-6-10-15(4)11-12-16/h7,9,11,16H,5-6,8,10,12H2,1-4H3/b14-9+,15-11+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	MMDB PDB Article PubMed	5.00E+3	-30.3	n/a	n/a	n/a	n/a	n/a	7.4	25
Emory University					Assay Description MAO A and MAO B activities were determined spectrophotometrically. Competitive Ki values for both enzymes were determined by measuring initial rates ...				J Biol Chem 280: 15761-6 (2005) Article DOI: 10.1074/jbc.M500949200 BindingDB Entry DOI: 10.7270/Q2DR2SP5
					More data for this Ligand-Target Pair				3D Structure (crystal)
Monoamine Oxidase Type B (MAO-B) (Bos taurus)	BDBM11022 (2,3-dihydro-1H-indole-2,3-dione | CHEMBL326294 | I...) Show SMILES O=C1Nc2ccccc2C1=O Show InChI InChI=1S/C8H5NO2/c10-7-5-3-1-2-4-6(5)9-8(7)11/h1-4H,(H,9,10,11)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	MMDB PDB Article PubMed	6.00E+3	-29.8	n/a	n/a	n/a	n/a	n/a	7.4	25
Emory University					Assay Description MAO A and MAO B activities were determined spectrophotometrically. Competitive Ki values for both enzymes were determined by measuring initial rates ...				J Biol Chem 280: 15761-6 (2005) Article DOI: 10.1074/jbc.M500949200 BindingDB Entry DOI: 10.7270/Q2DR2SP5
					More data for this Ligand-Target Pair				3D Structure (crystal)
Monoamine Oxidase Type B (MAO-B) (Rattus norvegicus (rat))	BDBM11020 (1,4-diphenyl-2-butene (DPB) | [(2E)-4-phenylbut-2-...) Show SMILES C(\C=C\Cc1ccccc1)c1ccccc1 Show InChI InChI=1S/C16H16/c1-3-9-15(10-4-1)13-7-8-14-16-11-5-2-6-12-16/h1-12H,13-14H2/b8-7+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Patents	Article PubMed	6.00E+3	-29.8	n/a	n/a	n/a	n/a	n/a	7.4	25
Emory University					Assay Description MAO A and MAO B activities were determined spectrophotometrically. Competitive Ki values for both enzymes were determined by measuring initial rates ...				J Biol Chem 280: 15761-6 (2005) Article DOI: 10.1074/jbc.M500949200 BindingDB Entry DOI: 10.7270/Q2DR2SP5
					More data for this Ligand-Target Pair
Monoamine Oxidase Type B (MAO-B) (Equus caballus (horse))	BDBM11020 (1,4-diphenyl-2-butene (DPB) | [(2E)-4-phenylbut-2-...) Show SMILES C(\C=C\Cc1ccccc1)c1ccccc1 Show InChI InChI=1S/C16H16/c1-3-9-15(10-4-1)13-7-8-14-16-11-5-2-6-12-16/h1-12H,13-14H2/b8-7+	PDB GoogleScholar AffyNet	PC cid PC sid UniChem Patents	Article PubMed	8.30E+3	-29.0	n/a	n/a	n/a	n/a	n/a	7.4	25
Emory University					Assay Description MAO A and MAO B activities were determined spectrophotometrically. Competitive Ki values for both enzymes were determined by measuring initial rates ...				J Biol Chem 280: 15761-6 (2005) Article DOI: 10.1074/jbc.M500949200 BindingDB Entry DOI: 10.7270/Q2DR2SP5
					More data for this Ligand-Target Pair
Monoamine Oxidase Type B (MAO-B) (Ovis aries (sheep))	BDBM11018 (2-[(E)-2-(3-chlorophenyl)ethenyl]-3,5,7-trimethyl-...) Show SMILES CC1c2nc(\C=C\c3cccc(Cl)c3)n(C)c2C(=O)N(C)C1=O Show InChI InChI=1S/C17H16ClN3O2/c1-10-14-15(17(23)21(3)16(10)22)20(2)13(19-14)8-7-11-5-4-6-12(18)9-11/h4-10H,1-3H3/b8-7+	PDB GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	>1.00E+6	>-17.1	n/a	n/a	n/a	n/a	n/a	7.4	25
Emory University					Assay Description MAO A and MAO B activities were determined spectrophotometrically. Competitive Ki values for both enzymes were determined by measuring initial rates ...				J Biol Chem 280: 15761-6 (2005) Article DOI: 10.1074/jbc.M500949200 BindingDB Entry DOI: 10.7270/Q2DR2SP5
					More data for this Ligand-Target Pair
Monoamine Oxidase Type B (MAO-B) (Ovis aries (sheep))	BDBM11020 (1,4-diphenyl-2-butene (DPB) | [(2E)-4-phenylbut-2-...) Show SMILES C(\C=C\Cc1ccccc1)c1ccccc1 Show InChI InChI=1S/C16H16/c1-3-9-15(10-4-1)13-7-8-14-16-11-5-2-6-12-16/h1-12H,13-14H2/b8-7+	PDB GoogleScholar AffyNet	PC cid PC sid UniChem Patents	Article PubMed	>1.00E+6	>-17.1	n/a	n/a	n/a	n/a	n/a	7.4	25
Emory University					Assay Description MAO A and MAO B activities were determined spectrophotometrically. Competitive Ki values for both enzymes were determined by measuring initial rates ...				J Biol Chem 280: 15761-6 (2005) Article DOI: 10.1074/jbc.M500949200 BindingDB Entry DOI: 10.7270/Q2DR2SP5
					More data for this Ligand-Target Pair
Monoamine Oxidase Type B (MAO-B) (Bos taurus)	BDBM11020 (1,4-diphenyl-2-butene (DPB) | [(2E)-4-phenylbut-2-...) Show SMILES C(\C=C\Cc1ccccc1)c1ccccc1 Show InChI InChI=1S/C16H16/c1-3-9-15(10-4-1)13-7-8-14-16-11-5-2-6-12-16/h1-12H,13-14H2/b8-7+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Patents	Article PubMed	>1.00E+6	>-17.1	n/a	n/a	n/a	n/a	n/a	7.4	25
Emory University					Assay Description MAO A and MAO B activities were determined spectrophotometrically. Competitive Ki values for both enzymes were determined by measuring initial rates ...				J Biol Chem 280: 15761-6 (2005) Article DOI: 10.1074/jbc.M500949200 BindingDB Entry DOI: 10.7270/Q2DR2SP5
					More data for this Ligand-Target Pair
Monoamine Oxidase Type B (MAO-B) (Bos taurus)	BDBM11021 ((2E,6E)-3,7,11-trimethyldodeca-2,6,10-trien-1-ol |...) Show SMILES CC(C)=CCC\C(C)=C\CC\C(C)=C\CO Show InChI InChI=1S/C15H26O/c1-13(2)7-5-8-14(3)9-6-10-15(4)11-12-16/h7,9,11,16H,5-6,8,10,12H2,1-4H3/b14-9+,15-11+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	MMDB PDB Article PubMed	>1.00E+6	>-17.1	n/a	n/a	n/a	n/a	n/a	7.4	25
Emory University					Assay Description MAO A and MAO B activities were determined spectrophotometrically. Competitive Ki values for both enzymes were determined by measuring initial rates ...				J Biol Chem 280: 15761-6 (2005) Article DOI: 10.1074/jbc.M500949200 BindingDB Entry DOI: 10.7270/Q2DR2SP5
					More data for this Ligand-Target Pair				3D Structure (crystal)
Monoamine Oxidase Type B (MAO-B) (Bos taurus)	BDBM11018 (2-[(E)-2-(3-chlorophenyl)ethenyl]-3,5,7-trimethyl-...) Show SMILES CC1c2nc(\C=C\c3cccc(Cl)c3)n(C)c2C(=O)N(C)C1=O Show InChI InChI=1S/C17H16ClN3O2/c1-10-14-15(17(23)21(3)16(10)22)20(2)13(19-14)8-7-11-5-4-6-12(18)9-11/h4-10H,1-3H3/b8-7+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	>1.00E+6	>-17.1	n/a	n/a	n/a	n/a	n/a	7.4	25
Emory University					Assay Description MAO A and MAO B activities were determined spectrophotometrically. Competitive Ki values for both enzymes were determined by measuring initial rates ...				J Biol Chem 280: 15761-6 (2005) Article DOI: 10.1074/jbc.M500949200 BindingDB Entry DOI: 10.7270/Q2DR2SP5
					More data for this Ligand-Target Pair
Monoamine Oxidase Type B (MAO-B) (Rattus norvegicus (rat))	BDBM36552 (Prochelators, 2) Show SMILES CN(CC#C)Cc1ccc(OC(=O)N(C)C)c2ncccc12 Show InChI InChI=1S/C17H19N3O2/c1-5-11-20(4)12-13-8-9-15(22-17(21)19(2)3)16-14(13)7-6-10-18-16/h1,6-10H,11-12H2,2-4H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.90E+3	n/a	n/a	n/a	n/a	7.4	37
The Weizmann Institute of Science					Assay Description Inhibition of MAO activity in rat brain homogenates.				ACS Chem Biol 5: 603-10 (2010) Article DOI: 10.1021/cb900264w BindingDB Entry DOI: 10.7270/Q2959FX1
					More data for this Ligand-Target Pair
Monoamine Oxidase Type B (MAO-B) (Rattus norvegicus (rat))	BDBM36551 (Chelator, M30 | US9034303, M30) Show SMILES CN(CC#C)Cc1ccc(O)c2ncccc12 Show InChI InChI=1S/C14H14N2O/c1-3-9-16(2)10-11-6-7-13(17)14-12(11)5-4-8-15-14/h1,4-8,17H,9-10H2,2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	37	n/a	n/a	n/a	n/a	7.4	37
The Weizmann Institute of Science					Assay Description Inhibition of MAO activity in rat brain homogenates.				ACS Chem Biol 5: 603-10 (2010) Article DOI: 10.1021/cb900264w BindingDB Entry DOI: 10.7270/Q2959FX1
					More data for this Ligand-Target Pair