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Found 69 of ph data with Target = 'Monocarboxylate transporter 1'
TargetMonocarboxylate transporter 1(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM22025(5-{[(3R)-3-hydroxypyrrolidin-1-yl]carbonyl}-6-(1H-...)
Affinity DataKi:  0.790nM ΔG°:  -51.4kJ/molepH: 7.4 T: 2°CAssay Description:A radioligand-binding assay was developed using scintillation proximity assay (SPA) technology. The wheat germ agglutinin SPA beads (Amersham) (0.2 m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonocarboxylate transporter 1(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM22024(5-{[(3R)-3-hydroxypyrrolidin-1-yl]carbonyl}-6-(iso...)
Affinity DataKi:  3.90nM ΔG°:  -47.5kJ/molepH: 7.4 T: 2°CAssay Description:A radioligand-binding assay was developed using scintillation proximity assay (SPA) technology. The wheat germ agglutinin SPA beads (Amersham) (0.2 m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonocarboxylate transporter 1(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM22026(5-{[(3R)-3-hydroxypyrrolidin-1-yl]carbonyl}-3-meth...)
Affinity DataKi:  4.70nM ΔG°:  -47.1kJ/molepH: 7.4 T: 2°CAssay Description:A radioligand-binding assay was developed using scintillation proximity assay (SPA) technology. The wheat germ agglutinin SPA beads (Amersham) (0.2 m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonocarboxylate transporter 1(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM21985(5-{[(3R)-3-hydroxypyrrolidin-1-yl]carbonyl}-3-meth...)
Affinity DataKi:  4.80nM ΔG°:  -47.0kJ/molepH: 7.4 T: 2°CAssay Description:A radioligand-binding assay was developed using scintillation proximity assay (SPA) technology. The wheat germ agglutinin SPA beads (Amersham) (0.2 m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonocarboxylate transporter 1(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM22023(5-{[(3R)-3-hydroxypyrrolidin-1-yl]carbonyl}-3-meth...)
Affinity DataKi:  5.30nM ΔG°:  -46.8kJ/molepH: 7.4 T: 2°CAssay Description:A radioligand-binding assay was developed using scintillation proximity assay (SPA) technology. The wheat germ agglutinin SPA beads (Amersham) (0.2 m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonocarboxylate transporter 1(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM22027(5-{[(3R)-3-hydroxypyrrolidin-1-yl]carbonyl}-3-meth...)
Affinity DataKi:  6.60nM ΔG°:  -46.2kJ/molepH: 7.4 T: 2°CAssay Description:A radioligand-binding assay was developed using scintillation proximity assay (SPA) technology. The wheat germ agglutinin SPA beads (Amersham) (0.2 m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonocarboxylate transporter 1(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM22028(5-{[(3R)-3-hydroxypyrrolidin-1-yl]carbonyl}-3-meth...)
Affinity DataKi:  16nM ΔG°:  -44.0kJ/molepH: 7.4 T: 2°CAssay Description:A radioligand-binding assay was developed using scintillation proximity assay (SPA) technology. The wheat germ agglutinin SPA beads (Amersham) (0.2 m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonocarboxylate transporter 1(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM22029(6-[(4,5-dichloro-2-methyl-1H-imidazol-1-yl)methyl]...)
Affinity DataKi:  26nM ΔG°:  -42.9kJ/molepH: 7.4 T: 2°CAssay Description:A radioligand-binding assay was developed using scintillation proximity assay (SPA) technology. The wheat germ agglutinin SPA beads (Amersham) (0.2 m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonocarboxylate transporter 1(Rattus norvegicus (Rat))
Regents Of The University Of Minnesota

US Patent
LigandPNGBDBM214704(US9296728, 28)
Affinity DataIC50:  920nMpH: 7.43 T: 2°CAssay Description:The entire lactate uptake studies for the inhibition of MCT1 were carried out on RBE4 (Rat Brain Endothelial 4) cells. The expression of MCT1 on thes...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonocarboxylate transporter 1(Rattus norvegicus (Rat))
Regents Of The University Of Minnesota

US Patent
LigandPNGBDBM214705(US9296728, 29)
Affinity DataIC50:  110nMpH: 7.43 T: 2°CAssay Description:The entire lactate uptake studies for the inhibition of MCT1 were carried out on RBE4 (Rat Brain Endothelial 4) cells. The expression of MCT1 on thes...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonocarboxylate transporter 1(Rattus norvegicus (Rat))
Regents Of The University Of Minnesota

US Patent
LigandPNGBDBM214703(US9296728, 27)
Affinity DataIC50:  200nMpH: 7.43 T: 2°CAssay Description:The entire lactate uptake studies for the inhibition of MCT1 were carried out on RBE4 (Rat Brain Endothelial 4) cells. The expression of MCT1 on thes...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonocarboxylate transporter 1(Rattus norvegicus (Rat))
Regents Of The University Of Minnesota

US Patent
LigandPNGBDBM50442702(CHEMBL2442511 | US9296728, 26)
Affinity DataIC50:  220nMpH: 7.43 T: 2°CAssay Description:The entire lactate uptake studies for the inhibition of MCT1 were carried out on RBE4 (Rat Brain Endothelial 4) cells. The expression of MCT1 on thes...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMonocarboxylate transporter 1(Rattus norvegicus (Rat))
Regents Of The University Of Minnesota

US Patent
LigandPNGBDBM214702(US9296728, 25)
Affinity DataIC50:  48nMpH: 7.43 T: 2°CAssay Description:The entire lactate uptake studies for the inhibition of MCT1 were carried out on RBE4 (Rat Brain Endothelial 4) cells. The expression of MCT1 on thes...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonocarboxylate transporter 1(Rattus norvegicus (Rat))
Regents Of The University Of Minnesota

US Patent
LigandPNGBDBM214701(US9296728, 24)
Affinity DataIC50:  150nMpH: 7.43 T: 2°CAssay Description:The entire lactate uptake studies for the inhibition of MCT1 were carried out on RBE4 (Rat Brain Endothelial 4) cells. The expression of MCT1 on thes...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonocarboxylate transporter 1(Rattus norvegicus (Rat))
Regents Of The University Of Minnesota

US Patent
LigandPNGBDBM214700(US9296728, 23)
Affinity DataIC50:  250nMpH: 7.43 T: 2°CAssay Description:The entire lactate uptake studies for the inhibition of MCT1 were carried out on RBE4 (Rat Brain Endothelial 4) cells. The expression of MCT1 on thes...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonocarboxylate transporter 1(Rattus norvegicus (Rat))
Regents Of The University Of Minnesota

US Patent
LigandPNGBDBM214699(US9296728, 22)
Affinity DataIC50:  299nMpH: 7.43 T: 2°CAssay Description:The entire lactate uptake studies for the inhibition of MCT1 were carried out on RBE4 (Rat Brain Endothelial 4) cells. The expression of MCT1 on thes...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonocarboxylate transporter 1(Rattus norvegicus (Rat))
Regents Of The University Of Minnesota

US Patent
LigandPNGBDBM214698(US9296728, 21)
Affinity DataIC50:  59nMpH: 7.43 T: 2°CAssay Description:The entire lactate uptake studies for the inhibition of MCT1 were carried out on RBE4 (Rat Brain Endothelial 4) cells. The expression of MCT1 on thes...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonocarboxylate transporter 1(Rattus norvegicus (Rat))
Regents Of The University Of Minnesota

US Patent
LigandPNGBDBM50092069(CHEMBL3582422 | US9296728, 20)
Affinity DataIC50:  8nMpH: 7.43 T: 2°CAssay Description:The entire lactate uptake studies for the inhibition of MCT1 were carried out on RBE4 (Rat Brain Endothelial 4) cells. The expression of MCT1 on thes...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMonocarboxylate transporter 1(Rattus norvegicus (Rat))
Regents Of The University Of Minnesota

US Patent
LigandPNGBDBM214697(US9296728, 19)
Affinity DataIC50:  19nMpH: 7.43 T: 2°CAssay Description:The entire lactate uptake studies for the inhibition of MCT1 were carried out on RBE4 (Rat Brain Endothelial 4) cells. The expression of MCT1 on thes...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonocarboxylate transporter 1(Rattus norvegicus (Rat))
Regents Of The University Of Minnesota

US Patent
LigandPNGBDBM50092071(CHEMBL3582420 | US9296728, 18)
Affinity DataIC50:  15nMpH: 7.43 T: 2°CAssay Description:The entire lactate uptake studies for the inhibition of MCT1 were carried out on RBE4 (Rat Brain Endothelial 4) cells. The expression of MCT1 on thes...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMonocarboxylate transporter 1(Rattus norvegicus (Rat))
Regents Of The University Of Minnesota

US Patent
LigandPNGBDBM214696(US9296728, 17)
Affinity DataIC50:  91nMpH: 7.43 T: 2°CAssay Description:The entire lactate uptake studies for the inhibition of MCT1 were carried out on RBE4 (Rat Brain Endothelial 4) cells. The expression of MCT1 on thes...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonocarboxylate transporter 1(Rattus norvegicus (Rat))
Regents Of The University Of Minnesota

US Patent
LigandPNGBDBM50092067(CHEMBL3582424 | US9296728, 16)
Affinity DataIC50:  25nMpH: 7.43 T: 2°CAssay Description:The entire lactate uptake studies for the inhibition of MCT1 were carried out on RBE4 (Rat Brain Endothelial 4) cells. The expression of MCT1 on thes...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMonocarboxylate transporter 1(Rattus norvegicus (Rat))
Regents Of The University Of Minnesota

US Patent
LigandPNGBDBM50092070(CHEMBL3582421 | US9296728, 15)
Affinity DataIC50:  23nMpH: 7.43 T: 2°CAssay Description:The entire lactate uptake studies for the inhibition of MCT1 were carried out on RBE4 (Rat Brain Endothelial 4) cells. The expression of MCT1 on thes...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMonocarboxylate transporter 1(Rattus norvegicus (Rat))
Regents Of The University Of Minnesota

US Patent
LigandPNGBDBM50092072(CHEMBL3582419 | US9296728, 14)
Affinity DataIC50:  7.60nMpH: 7.43 T: 2°CAssay Description:The entire lactate uptake studies for the inhibition of MCT1 were carried out on RBE4 (Rat Brain Endothelial 4) cells. The expression of MCT1 on thes...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMonocarboxylate transporter 1(Rattus norvegicus (Rat))
Regents Of The University Of Minnesota

US Patent
LigandPNGBDBM50092073(CHEMBL3582418 | US9296728, 13)
Affinity DataIC50:  9.5nMpH: 7.43 T: 2°CAssay Description:The entire lactate uptake studies for the inhibition of MCT1 were carried out on RBE4 (Rat Brain Endothelial 4) cells. The expression of MCT1 on thes...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMonocarboxylate transporter 1(Rattus norvegicus (Rat))
Regents Of The University Of Minnesota

US Patent
LigandPNGBDBM50092074(CHEMBL3582417 | US9296728, 12)
Affinity DataIC50:  110nMpH: 7.43 T: 2°CAssay Description:The entire lactate uptake studies for the inhibition of MCT1 were carried out on RBE4 (Rat Brain Endothelial 4) cells. The expression of MCT1 on thes...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMonocarboxylate transporter 1(Rattus norvegicus (Rat))
Regents Of The University Of Minnesota

US Patent
LigandPNGBDBM50092075(CHEMBL3582416 | US9296728, 11)
Affinity DataIC50:  64nMpH: 7.43 T: 2°CAssay Description:The entire lactate uptake studies for the inhibition of MCT1 were carried out on RBE4 (Rat Brain Endothelial 4) cells. The expression of MCT1 on thes...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMonocarboxylate transporter 1(Rattus norvegicus (Rat))
Regents Of The University Of Minnesota

US Patent
LigandPNGBDBM50092057(CHEMBL3582409 | US9296728, 4)
Affinity DataIC50:  26nMpH: 7.43 T: 2°CAssay Description:The entire lactate uptake studies for the inhibition of MCT1 were carried out on RBE4 (Rat Brain Endothelial 4) cells. The expression of MCT1 on thes...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMonocarboxylate transporter 1(Rattus norvegicus (Rat))
Regents Of The University Of Minnesota

US Patent
LigandPNGBDBM50092017(CHEMBL3582411 | US9296728, 5)
Affinity DataIC50:  120nMpH: 7.43 T: 2°CAssay Description:The entire lactate uptake studies for the inhibition of MCT1 were carried out on RBE4 (Rat Brain Endothelial 4) cells. The expression of MCT1 on thes...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMonocarboxylate transporter 1(Rattus norvegicus (Rat))
Regents Of The University Of Minnesota

US Patent
LigandPNGBDBM50092016(CHEMBL3582412 | US9296728, 6)
Affinity DataIC50:  950nMpH: 7.43 T: 2°CAssay Description:The entire lactate uptake studies for the inhibition of MCT1 were carried out on RBE4 (Rat Brain Endothelial 4) cells. The expression of MCT1 on thes...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMonocarboxylate transporter 1(Rattus norvegicus (Rat))
Regents Of The University Of Minnesota

US Patent
LigandPNGBDBM50092078(CHEMBL3582413 | US9296728, 7)
Affinity DataIC50:  88nMpH: 7.43 T: 2°CAssay Description:The entire lactate uptake studies for the inhibition of MCT1 were carried out on RBE4 (Rat Brain Endothelial 4) cells. The expression of MCT1 on thes...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMonocarboxylate transporter 1(Rattus norvegicus (Rat))
Regents Of The University Of Minnesota

US Patent
LigandPNGBDBM50092077(CHEMBL3582414 | US9296728, 8)
Affinity DataIC50:  340nMpH: 7.43 T: 2°CAssay Description:The entire lactate uptake studies for the inhibition of MCT1 were carried out on RBE4 (Rat Brain Endothelial 4) cells. The expression of MCT1 on thes...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMonocarboxylate transporter 1(Rattus norvegicus (Rat))
Regents Of The University Of Minnesota

US Patent
LigandPNGBDBM50092018(CHEMBL3582410 | US9296728, 9)
Affinity DataIC50:  66nMpH: 7.43 T: 2°CAssay Description:The entire lactate uptake studies for the inhibition of MCT1 were carried out on RBE4 (Rat Brain Endothelial 4) cells. The expression of MCT1 on thes...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMonocarboxylate transporter 1(Rattus norvegicus (Rat))
Regents Of The University Of Minnesota

US Patent
LigandPNGBDBM214695(US9296728, 10)
Affinity DataIC50:  43nMpH: 7.43 T: 2°CAssay Description:The entire lactate uptake studies for the inhibition of MCT1 were carried out on RBE4 (Rat Brain Endothelial 4) cells. The expression of MCT1 on thes...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonocarboxylate transporter 1(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM21995(5-{[(4S)-4-hydroxy-1,2-oxazolidin-2-yl]carbonyl}-3...)
Affinity DataKi:  0.0900nM ΔG°:  -56.8kJ/molepH: 7.8 T: 2°CAssay Description:Jurkat cell membranes were incubated with [3H]-labeled ligand in the absence or presence of increasing concentrations of test compound. The reagents ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonocarboxylate transporter 1(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM22000(7-[(3-hydroxypropyl)sulfanyl]-2-methyl-4-(2-methyl...)
Affinity DataKi:  0.100nM ΔG°:  -56.5kJ/molepH: 7.8 T: 2°CAssay Description:Jurkat cell membranes were incubated with [3H]-labeled ligand in the absence or presence of increasing concentrations of test compound. The reagents ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonocarboxylate transporter 1(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM22001(5-[(3-hydroxypropyl)sulfanyl]-3-methyl-1-(2-methyl...)
Affinity DataKi:  0.280nM ΔG°:  -54.0kJ/molepH: 7.8 T: 2°CAssay Description:Jurkat cell membranes were incubated with [3H]-labeled ligand in the absence or presence of increasing concentrations of test compound. The reagents ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonocarboxylate transporter 1(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM22009(5-{[(1R,3R)-3-hydroxycyclopentyl]sulfanyl}-3-methy...)
Affinity DataKi:  0.290nM ΔG°:  -53.9kJ/molepH: 7.8 T: 2°CAssay Description:Jurkat cell membranes were incubated with [3H]-labeled ligand in the absence or presence of increasing concentrations of test compound. The reagents ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonocarboxylate transporter 1(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM21992(5-{[(3R)-3-hydroxypyrrolidin-1-yl]carbonyl}-3-meth...)
Affinity DataKi:  0.310nM ΔG°:  -53.7kJ/molepH: 7.8 T: 2°CAssay Description:Jurkat cell membranes were incubated with [3H]-labeled ligand in the absence or presence of increasing concentrations of test compound. The reagents ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMonocarboxylate transporter 1(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM21986(5-[(3-hydroxypropyl)sulfanyl]-3-methyl-1-(2-methyl...)
Affinity DataKi:  0.330nM ΔG°:  -53.6kJ/molepH: 7.8 T: 2°CAssay Description:Jurkat cell membranes were incubated with [3H]-labeled ligand in the absence or presence of increasing concentrations of test compound. The reagents ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonocarboxylate transporter 1(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM22002(5-[(3-hydroxypropyl)sulfanyl]-3-methyl-1-(2-methyl...)
Affinity DataKi:  0.350nM ΔG°:  -53.4kJ/molepH: 7.8 T: 2°CAssay Description:Jurkat cell membranes were incubated with [3H]-labeled ligand in the absence or presence of increasing concentrations of test compound. The reagents ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonocarboxylate transporter 1(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM22010(5-{[(1R,3S)-3-hydroxycyclopentyl]sulfanyl}-3-methy...)
Affinity DataKi:  0.420nM ΔG°:  -53.0kJ/molepH: 7.8 T: 2°CAssay Description:Jurkat cell membranes were incubated with [3H]-labeled ligand in the absence or presence of increasing concentrations of test compound. The reagents ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonocarboxylate transporter 1(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM21996(5-{[(4S)-4-hydroxy-1,2-oxazolidin-2-yl]carbonyl}-3...)
Affinity DataKi:  0.430nM ΔG°:  -52.9kJ/molepH: 7.8 T: 2°CAssay Description:Jurkat cell membranes were incubated with [3H]-labeled ligand in the absence or presence of increasing concentrations of test compound. The reagents ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonocarboxylate transporter 1(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM21994(5-{[(4S)-4-hydroxy-1,2-oxazolidin-2-yl]carbonyl}-3...)
Affinity DataKi:  0.520nM ΔG°:  -52.5kJ/molepH: 7.8 T: 2°CAssay Description:Jurkat cell membranes were incubated with [3H]-labeled ligand in the absence or presence of increasing concentrations of test compound. The reagents ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonocarboxylate transporter 1(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM22011(5-{[(1S,3R,4S)-3,4-dihydroxycyclopentyl]sulfanyl}-...)
Affinity DataKi:  0.680nM ΔG°:  -51.8kJ/molepH: 7.8 T: 2°CAssay Description:Jurkat cell membranes were incubated with [3H]-labeled ligand in the absence or presence of increasing concentrations of test compound. The reagents ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonocarboxylate transporter 1(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM21987(6-[(6-fluoroquinolin-4-yl)methyl]-5-{[(3R)-3-hydro...)
Affinity DataKi:  0.810nM ΔG°:  -51.4kJ/molepH: 7.8 T: 2°CAssay Description:Jurkat cell membranes were incubated with [3H]-labeled ligand in the absence or presence of increasing concentrations of test compound. The reagents ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonocarboxylate transporter 1(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM22014(5-{[(3R)-3-hydroxypyrrolidine-1-]sulfonyl}-3-methy...)
Affinity DataKi:  1.10nM ΔG°:  -50.6kJ/molepH: 7.8 T: 2°CAssay Description:Jurkat cell membranes were incubated with [3H]-labeled ligand in the absence or presence of increasing concentrations of test compound. The reagents ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonocarboxylate transporter 1(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM21998(6-[(3,5-dimethyl-1H-pyrazol-4-yl)methyl]-5-{[(4S)-...)
Affinity DataKi:  1.20nM ΔG°:  -50.4kJ/molepH: 7.8 T: 2°CAssay Description:Jurkat cell membranes were incubated with [3H]-labeled ligand in the absence or presence of increasing concentrations of test compound. The reagents ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonocarboxylate transporter 1(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM21997(5-{[(4S)-4-hydroxy-1,2-oxazolidin-2-yl]carbonyl}-3...)
Affinity DataKi:  1.70nM ΔG°:  -49.6kJ/molepH: 7.8 T: 2°CAssay Description:Jurkat cell membranes were incubated with [3H]-labeled ligand in the absence or presence of increasing concentrations of test compound. The reagents ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonocarboxylate transporter 1(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM22004(3-methyl-1-(2-methylpropyl)-5-(propan-2-ylsulfanyl...)
Affinity DataKi:  2.20nM ΔG°:  -48.9kJ/molepH: 7.8 T: 2°CAssay Description:Jurkat cell membranes were incubated with [3H]-labeled ligand in the absence or presence of increasing concentrations of test compound. The reagents ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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