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Compile Data Set for Download or QSAR

Found 164 hits of ph data with Target = 'Neuraminidase A'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Neuraminidase A


(Influenza A virus (A/Shangdong/9/93(H3N2)))
BDBM4934
PNG
((2R,3R,4S)-4-carbamimidamido-3-acetamido-2-[(1R,2R...)
Show SMILES CC(=O)N[C@@H]1[C@H](C=C(O[C@H]1[C@H](O)[C@H](O)CO)C(O)=O)N=C(N)N
Show InChI InChI=1S/C12H20N4O7/c1-4(18)15-8-5(16-12(13)14)2-7(11(21)22)23-10(8)9(20)6(19)3-17/h2,5-6,8-10,17,19-20H,3H2,1H3,(H,15,18)(H,21,22)(H4,13,14,16)/t5-,6+,8+,9+,10+/m0/s1
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Article
1 -53.4 5n/an/an/an/a6.537



Gilead Sciences Inc.



Assay Description
A standard fluorimetric assay was used to measure influenza virus neuraminidase activity. The substrate 2 -(4-methylumbelliferyl)-alpha-D-acetylneura...


Bioorg Med Chem Lett 7: 1837-42 (1997)


Article DOI: 10.1021/jm048989d
BindingDB Entry DOI: 10.7270/Q2FX77MK
More data for this
Ligand-Target Pair
Neuraminidase A


(Influenza A virus (A/Shangdong/9/93(H3N2)))
BDBM5210
PNG
(3-carbamimidamido-4-acetamido-5-[(1S,2R)-1,2,3-tri...)
Show SMILES CC(=O)Nc1c(cc(cc1[C@H](O)[C@H](O)CO)C(O)=O)N=C(N)N
Show InChI InChI=1S/C13H18N4O6/c1-5(19)16-10-7(11(21)9(20)4-18)2-6(12(22)23)3-8(10)17-13(14)15/h2-3,9,11,18,20-21H,4H2,1H3,(H,16,19)(H,22,23)(H4,14,15,17)/t9-,11+/m1/s1
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>1.00E+5>-23.7>1.00E+5n/an/an/an/a6.537



Gilead Sciences Inc.



Assay Description
A standard fluorimetric assay was used to measure influenza virus neuraminidase activity. The substrate 2 -(4-methylumbelliferyl)-alpha-D-acetylneura...


Bioorg Med Chem Lett 7: 1837-42 (1997)


Article DOI: 10.1021/jm048989d
BindingDB Entry DOI: 10.7270/Q2FX77MK
More data for this
Ligand-Target Pair
Neuraminidase A


(Influenza A virus (A/Puerto Rico/8/34/Mount Sinai(...)
BDBM5250
PNG
((3R,4R,5S)-5-amino-3-(azetidin-1-yl)-4-acetamidocy...)
Show SMILES CC(=O)N[C@@H]1[C@@H](N)CC(=C[C@H]1N1CCC1)C(O)=O
Show InChI InChI=1S/C12H19N3O3/c1-7(16)14-11-9(13)5-8(12(17)18)6-10(11)15-3-2-4-15/h6,9-11H,2-5,13H2,1H3,(H,14,16)(H,17,18)/t9-,10+,11+/m0/s1
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n/an/a 1.00E+3n/an/an/an/a6.537



Gilead Sciences Inc.



Assay Description
A standard fluorimetric assay was used to measure influenza virus neuraminidase activity. The substrate 2 -(4-methylumbelliferyl)-alpha-D-acetylneura...


Bioorg Med Chem Lett 10: 1257-60 (2000)


Article DOI: 10.1016/s0960-894x(00)00214-6
BindingDB Entry DOI: 10.7270/Q22R3PWW
More data for this
Ligand-Target Pair
Neuraminidase A


(Influenza A virus (A/Puerto Rico/8/34/Mount Sinai(...)
BDBM5251
PNG
((3R,4R,5S)-5-amino-4-acetamido-3-(pyrrolidin-1-yl)...)
Show SMILES CC(=O)N[C@@H]1[C@@H](N)CC(=C[C@H]1N1CCCC1)C(O)=O
Show InChI InChI=1S/C13H21N3O3/c1-8(17)15-12-10(14)6-9(13(18)19)7-11(12)16-4-2-3-5-16/h7,10-12H,2-6,14H2,1H3,(H,15,17)(H,18,19)/t10-,11+,12+/m0/s1
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n/an/a 310n/an/an/an/a6.537



Gilead Sciences Inc.



Assay Description
A standard fluorimetric assay was used to measure influenza virus neuraminidase activity. The substrate 2 -(4-methylumbelliferyl)-alpha-D-acetylneura...


Bioorg Med Chem Lett 10: 1257-60 (2000)


Article DOI: 10.1016/s0960-894x(00)00214-6
BindingDB Entry DOI: 10.7270/Q22R3PWW
More data for this
Ligand-Target Pair
Neuraminidase A


(Influenza A virus (A/Puerto Rico/8/34/Mount Sinai(...)
BDBM5252
PNG
((3R,4R,5S)-5-amino-4-acetamido-3-(piperidin-1-yl)c...)
Show SMILES CC(=O)N[C@@H]1[C@@H](N)CC(=C[C@H]1N1CCCCC1)C(O)=O
Show InChI InChI=1S/C14H23N3O3/c1-9(18)16-13-11(15)7-10(14(19)20)8-12(13)17-5-3-2-4-6-17/h8,11-13H,2-7,15H2,1H3,(H,16,18)(H,19,20)/t11-,12+,13+/m0/s1
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n/an/a 25n/an/an/an/a6.537



Gilead Sciences Inc.



Assay Description
A standard fluorimetric assay was used to measure influenza virus neuraminidase activity. The substrate 2 -(4-methylumbelliferyl)-alpha-D-acetylneura...


Bioorg Med Chem Lett 10: 1257-60 (2000)


Article DOI: 10.1016/s0960-894x(00)00214-6
BindingDB Entry DOI: 10.7270/Q22R3PWW
More data for this
Ligand-Target Pair
Neuraminidase A


(Influenza A virus (A/Puerto Rico/8/34/Mount Sinai(...)
BDBM5253
PNG
((3R,4R,5S)-5-amino-3-(azepan-1-yl)-4-acetamidocycl...)
Show SMILES CC(=O)N[C@@H]1[C@@H](N)CC(=C[C@H]1N1CCCCCC1)C(O)=O
Show InChI InChI=1S/C15H25N3O3/c1-10(19)17-14-12(16)8-11(15(20)21)9-13(14)18-6-4-2-3-5-7-18/h9,12-14H,2-8,16H2,1H3,(H,17,19)(H,20,21)/t12-,13+,14+/m0/s1
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n/an/a 35n/an/an/an/a6.537



Gilead Sciences Inc.



Assay Description
A standard fluorimetric assay was used to measure influenza virus neuraminidase activity. The substrate 2 -(4-methylumbelliferyl)-alpha-D-acetylneura...


Bioorg Med Chem Lett 10: 1257-60 (2000)


Article DOI: 10.1016/s0960-894x(00)00214-6
BindingDB Entry DOI: 10.7270/Q22R3PWW
More data for this
Ligand-Target Pair
Neuraminidase A


(Influenza A virus (A/Puerto Rico/8/34/Mount Sinai(...)
BDBM5254
PNG
((3R,4R,5S)-5-amino-3-(azocan-1-yl)-4-acetamidocycl...)
Show SMILES CC(=O)N[C@@H]1[C@@H](N)CC(=C[C@H]1N1CCCCCCC1)C(O)=O
Show InChI InChI=1S/C16H27N3O3/c1-11(20)18-15-13(17)9-12(16(21)22)10-14(15)19-7-5-3-2-4-6-8-19/h10,13-15H,2-9,17H2,1H3,(H,18,20)(H,21,22)/t13-,14+,15+/m0/s1
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n/an/a 26n/an/an/an/a6.537



Gilead Sciences Inc.



Assay Description
A standard fluorimetric assay was used to measure influenza virus neuraminidase activity. The substrate 2 -(4-methylumbelliferyl)-alpha-D-acetylneura...


Bioorg Med Chem Lett 10: 1257-60 (2000)


Article DOI: 10.1016/s0960-894x(00)00214-6
BindingDB Entry DOI: 10.7270/Q22R3PWW
More data for this
Ligand-Target Pair
Neuraminidase A


(Influenza A virus (A/Puerto Rico/8/34/Mount Sinai(...)
BDBM5255
PNG
((3R,4R,5S)-5-amino-3-(azonan-1-yl)-4-acetamidocycl...)
Show SMILES CC(=O)N[C@@H]1[C@@H](N)CC(=C[C@H]1N1CCCCCCCC1)C(O)=O
Show InChI InChI=1S/C17H29N3O3/c1-12(21)19-16-14(18)10-13(17(22)23)11-15(16)20-8-6-4-2-3-5-7-9-20/h11,14-16H,2-10,18H2,1H3,(H,19,21)(H,22,23)/t14-,15+,16+/m0/s1
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n/an/a 75n/an/an/an/a6.537



Gilead Sciences Inc.



Assay Description
A standard fluorimetric assay was used to measure influenza virus neuraminidase activity. The substrate 2 -(4-methylumbelliferyl)-alpha-D-acetylneura...


Bioorg Med Chem Lett 10: 1257-60 (2000)


Article DOI: 10.1016/s0960-894x(00)00214-6
BindingDB Entry DOI: 10.7270/Q22R3PWW
More data for this
Ligand-Target Pair
Neuraminidase A


(Influenza A virus (A/Puerto Rico/8/34/Mount Sinai(...)
BDBM5256
PNG
((3R,4R,5S)-5-amino-3-(3,3-diethylazetidin-1-yl)-4-...)
Show SMILES CCC1(CC)CN(C1)[C@@H]1C=C(C[C@H](N)[C@H]1NC(C)=O)C(O)=O
Show InChI InChI=1S/C16H27N3O3/c1-4-16(5-2)8-19(9-16)13-7-11(15(21)22)6-12(17)14(13)18-10(3)20/h7,12-14H,4-6,8-9,17H2,1-3H3,(H,18,20)(H,21,22)/t12-,13+,14+/m0/s1
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n/an/a 265n/an/an/an/a6.537



Gilead Sciences Inc.



Assay Description
A standard fluorimetric assay was used to measure influenza virus neuraminidase activity. The substrate 2 -(4-methylumbelliferyl)-alpha-D-acetylneura...


Bioorg Med Chem Lett 10: 1257-60 (2000)


Article DOI: 10.1016/s0960-894x(00)00214-6
BindingDB Entry DOI: 10.7270/Q22R3PWW
More data for this
Ligand-Target Pair
Neuraminidase A


(Influenza A virus (A/Puerto Rico/8/34/Mount Sinai(...)
BDBM5257
PNG
((3R,4R,5S)-5-amino-4-acetamido-3-(morpholin-4-yl)c...)
Show SMILES CC(=O)N[C@@H]1[C@@H](N)CC(=C[C@H]1N1CCOCC1)C(O)=O
Show InChI InChI=1S/C13H21N3O4/c1-8(17)15-12-10(14)6-9(13(18)19)7-11(12)16-2-4-20-5-3-16/h7,10-12H,2-6,14H2,1H3,(H,15,17)(H,18,19)/t10-,11+,12+/m0/s1
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n/an/a 260n/an/an/an/a6.537



Gilead Sciences Inc.



Assay Description
A standard fluorimetric assay was used to measure influenza virus neuraminidase activity. The substrate 2 -(4-methylumbelliferyl)-alpha-D-acetylneura...


Bioorg Med Chem Lett 10: 1257-60 (2000)


Article DOI: 10.1016/s0960-894x(00)00214-6
BindingDB Entry DOI: 10.7270/Q22R3PWW
More data for this
Ligand-Target Pair
Neuraminidase A


(Influenza A virus (A/Puerto Rico/8/34/Mount Sinai(...)
BDBM5258
PNG
((3R,4R,5S)-5-amino-4-acetamido-3-(4-methylpiperazi...)
Show SMILES CN1CCN(CC1)[C@@H]1C=C(C[C@H](N)[C@H]1NC(C)=O)C(O)=O
Show InChI InChI=1S/C14H24N4O3/c1-9(19)16-13-11(15)7-10(14(20)21)8-12(13)18-5-3-17(2)4-6-18/h8,11-13H,3-7,15H2,1-2H3,(H,16,19)(H,20,21)/t11-,12+,13+/m0/s1
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n/an/a 1.90E+3n/an/an/an/a6.537



Gilead Sciences Inc.



Assay Description
A standard fluorimetric assay was used to measure influenza virus neuraminidase activity. The substrate 2 -(4-methylumbelliferyl)-alpha-D-acetylneura...


Bioorg Med Chem Lett 10: 1257-60 (2000)


Article DOI: 10.1016/s0960-894x(00)00214-6
BindingDB Entry DOI: 10.7270/Q22R3PWW
More data for this
Ligand-Target Pair
Neuraminidase A


(Influenza A virus (A/Puerto Rico/8/34/Mount Sinai(...)
BDBM5259
PNG
((3R,4R,5S)-5-amino-4-acetamido-3-(4-methylpiperidi...)
Show SMILES CC1CCN(CC1)[C@@H]1C=C(C[C@H](N)[C@H]1NC(C)=O)C(O)=O
Show InChI InChI=1S/C15H25N3O3/c1-9-3-5-18(6-4-9)13-8-11(15(20)21)7-12(16)14(13)17-10(2)19/h8-9,12-14H,3-7,16H2,1-2H3,(H,17,19)(H,20,21)/t12-,13+,14+/m0/s1
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n/an/a 51n/an/an/an/a6.537



Gilead Sciences Inc.



Assay Description
A standard fluorimetric assay was used to measure influenza virus neuraminidase activity. The substrate 2 -(4-methylumbelliferyl)-alpha-D-acetylneura...


Bioorg Med Chem Lett 10: 1257-60 (2000)


Article DOI: 10.1016/s0960-894x(00)00214-6
BindingDB Entry DOI: 10.7270/Q22R3PWW
More data for this
Ligand-Target Pair
Neuraminidase A


(Influenza A virus (A/Puerto Rico/8/34/Mount Sinai(...)
BDBM5260
PNG
((3R,4R,5S)-5-amino-4-acetamido-3-(4-ethylpiperidin...)
Show SMILES CCC1CCN(CC1)[C@@H]1C=C(C[C@H](N)[C@H]1NC(C)=O)C(O)=O
Show InChI InChI=1S/C16H27N3O3/c1-3-11-4-6-19(7-5-11)14-9-12(16(21)22)8-13(17)15(14)18-10(2)20/h9,11,13-15H,3-8,17H2,1-2H3,(H,18,20)(H,21,22)/t13-,14+,15+/m0/s1
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n/an/a 52n/an/an/an/a6.537



Gilead Sciences Inc.



Assay Description
A standard fluorimetric assay was used to measure influenza virus neuraminidase activity. The substrate 2 -(4-methylumbelliferyl)-alpha-D-acetylneura...


Bioorg Med Chem Lett 10: 1257-60 (2000)


Article DOI: 10.1016/s0960-894x(00)00214-6
BindingDB Entry DOI: 10.7270/Q22R3PWW
More data for this
Ligand-Target Pair
Neuraminidase A


(Influenza A virus (A/Puerto Rico/8/34/Mount Sinai(...)
BDBM5261
PNG
((3R,4R,5S)-5-amino-4-acetamido-3-(4-propylpiperidi...)
Show SMILES CCCC1CCN(CC1)[C@@H]1C=C(C[C@H](N)[C@H]1NC(C)=O)C(O)=O
Show InChI InChI=1S/C17H29N3O3/c1-3-4-12-5-7-20(8-6-12)15-10-13(17(22)23)9-14(18)16(15)19-11(2)21/h10,12,14-16H,3-9,18H2,1-2H3,(H,19,21)(H,22,23)/t14-,15+,16+/m0/s1
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n/an/a 40n/an/an/an/a6.537



Gilead Sciences Inc.



Assay Description
A standard fluorimetric assay was used to measure influenza virus neuraminidase activity. The substrate 2 -(4-methylumbelliferyl)-alpha-D-acetylneura...


Bioorg Med Chem Lett 10: 1257-60 (2000)


Article DOI: 10.1016/s0960-894x(00)00214-6
BindingDB Entry DOI: 10.7270/Q22R3PWW
More data for this
Ligand-Target Pair
Neuraminidase A


(Influenza A virus (A/Puerto Rico/8/34/Mount Sinai(...)
BDBM5262
PNG
((3R,4R,5S)-5-amino-3-{8-azabicyclo[3.2.1]octan-8-y...)
Show SMILES CC(=O)N[C@@H]1[C@@H](N)CC(=C[C@H]1N1C2CCC1CCC2)C(O)=O
Show InChI InChI=1S/C16H25N3O3/c1-9(20)18-15-13(17)7-10(16(21)22)8-14(15)19-11-3-2-4-12(19)6-5-11/h8,11-15H,2-7,17H2,1H3,(H,18,20)(H,21,22)/t11?,12?,13-,14+,15+/m0/s1
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n/an/a 32n/an/an/an/a6.537



Gilead Sciences Inc.



Assay Description
A standard fluorimetric assay was used to measure influenza virus neuraminidase activity. The substrate 2 -(4-methylumbelliferyl)-alpha-D-acetylneura...


Bioorg Med Chem Lett 10: 1257-60 (2000)


Article DOI: 10.1016/s0960-894x(00)00214-6
BindingDB Entry DOI: 10.7270/Q22R3PWW
More data for this
Ligand-Target Pair
Neuraminidase A


(Influenza A virus (A/Puerto Rico/8/34/Mount Sinai(...)
BDBM5263
PNG
((3R,4R,5S)-5-amino-4-acetamido-3-[(2R)-2-(hydroxym...)
Show SMILES CC(=O)N[C@@H]1[C@@H](N)CC(=C[C@H]1N1CCCCC[C@@H]1CO)C(O)=O
Show InChI InChI=1S/C16H27N3O4/c1-10(21)18-15-13(17)7-11(16(22)23)8-14(15)19-6-4-2-3-5-12(19)9-20/h8,12-15,20H,2-7,9,17H2,1H3,(H,18,21)(H,22,23)/t12-,13+,14-,15-/m1/s1
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n/an/a 8n/an/an/an/a6.537



Gilead Sciences Inc.



Assay Description
A standard fluorimetric assay was used to measure influenza virus neuraminidase activity. The substrate 2 -(4-methylumbelliferyl)-alpha-D-acetylneura...


Bioorg Med Chem Lett 10: 1257-60 (2000)


Article DOI: 10.1016/s0960-894x(00)00214-6
BindingDB Entry DOI: 10.7270/Q22R3PWW
More data for this
Ligand-Target Pair
Neuraminidase A


(Influenza A virus (A/Puerto Rico/8/34/Mount Sinai(...)
BDBM4994
PNG
((3R,4R,5S)-5-amino-4-acetamido-3-(pentan-3-yloxy)c...)
Show SMILES CCC(CC)O[C@@H]1C=C(C[C@H](N)[C@H]1NC(C)=O)C(O)=O
Show InChI InChI=1S/C14H24N2O4/c1-4-10(5-2)20-12-7-9(14(18)19)6-11(15)13(12)16-8(3)17/h7,10-13H,4-6,15H2,1-3H3,(H,16,17)(H,18,19)/t11-,12+,13+/m0/s1
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n/an/a 1n/an/an/an/a6.537



Gilead Sciences Inc.



Assay Description
A standard fluorimetric assay was used to measure influenza virus neuraminidase activity. The substrate 2 -(4-methylumbelliferyl)-alpha-D-acetylneura...


Bioorg Med Chem Lett 10: 1257-60 (2000)


Article DOI: 10.1016/s0960-894x(00)00214-6
BindingDB Entry DOI: 10.7270/Q22R3PWW
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Neuraminidase A


(Influenza A virus (A/Singapore/1/57(H2N2)))
BDBM5265
PNG
((2S,3S,4R)-4-carbamimidamido-3-acetamido-2-[(1R,2S...)
Show SMILES CC(=O)N[C@H]1[C@@H](C=C(O[C@@H]1[C@H](O)[C@@H](O)CO)C(O)=O)N=C(N)N
Show InChI InChI=1S/C12H20N4O7/c1-4(18)15-8-5(16-12(13)14)2-7(11(21)22)23-10(8)9(20)6(19)3-17/h2,5-6,8-10,17,19-20H,3H2,1H3,(H,15,18)(H,21,22)(H4,13,14,16)/t5-,6+,8+,9-,10+/m1/s1
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n/an/a 5n/an/an/an/a6.537



University of Alabama at Birmingham



Assay Description
A standard fluorimetric assay was used to measure influenza virus neuraminidase activity. The substrate 2 -(4-methylumbelliferyl)-alpha-D-acetylneura...


Bioorg Med Chem 7: 2487-97 (1999)


Article DOI: 10.1021/jm061112p
BindingDB Entry DOI: 10.7270/Q2Z036CV
More data for this
Ligand-Target Pair
Neuraminidase A


(Influenza A virus (A/Singapore/1/57(H2N2)))
BDBM5266
PNG
((2S,3S,4R)-4-carbamimidamido-2-(dipropylcarbamoyl)...)
Show SMILES CCCN(CCC)C(=O)[C@H]1OC(=C[C@@H](N=C(N)N)[C@@H]1NC(C)=O)C(O)=O
Show InChI InChI=1S/C16H27N5O5/c1-4-6-21(7-5-2)14(23)13-12(19-9(3)22)10(20-16(17)18)8-11(26-13)15(24)25/h8,10,12-13H,4-7H2,1-3H3,(H,19,22)(H,24,25)(H4,17,18,20)/t10-,12+,13+/m1/s1
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n/an/a 1n/an/an/an/a6.537



University of Alabama at Birmingham



Assay Description
A standard fluorimetric assay was used to measure influenza virus neuraminidase activity. The substrate 2 -(4-methylumbelliferyl)-alpha-D-acetylneura...


Bioorg Med Chem 7: 2487-97 (1999)


Article DOI: 10.1021/jm061112p
BindingDB Entry DOI: 10.7270/Q2Z036CV
More data for this
Ligand-Target Pair
Neuraminidase A


(Influenza A virus (N9))
BDBM5267
PNG
(4-(N-Acetylamino)-3-[N-(2-ethylbutanoyl)amino]benz...)
Show SMILES CCC(CC)C(=O)Nc1cc(ccc1NC(C)=O)C(O)=O
Show InChI InChI=1S/C15H20N2O4/c1-4-10(5-2)14(19)17-13-8-11(15(20)21)6-7-12(13)16-9(3)18/h6-8,10H,4-5H2,1-3H3,(H,16,18)(H,17,19)(H,20,21)
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n/an/a 2.70E+4n/an/an/an/a6.537



University of Alabama at Birmingham



Assay Description
A standard fluorimetric assay was used to measure influenza virus neuraminidase activity. The substrate 2 -(4-methylumbelliferyl)-alpha-D-acetylneura...


Bioorg Med Chem 7: 2487-97 (1999)


Article DOI: 10.1021/jm061112p
BindingDB Entry DOI: 10.7270/Q2Z036CV
More data for this
Ligand-Target Pair
Neuraminidase A


(Influenza A virus (N9))
BDBM5268
PNG
(4-(N- Acetylamino) -3 - [N- (3 - pentyl)amino]benz...)
Show SMILES CCC(CC)Nc1cc(ccc1NC(C)=O)C(O)=O
Show InChI InChI=1S/C14H20N2O3/c1-4-11(5-2)16-13-8-10(14(18)19)6-7-12(13)15-9(3)17/h6-8,11,16H,4-5H2,1-3H3,(H,15,17)(H,18,19)
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n/an/a 2.50E+4n/an/an/an/a6.537



University of Alabama at Birmingham



Assay Description
A standard fluorimetric assay was used to measure influenza virus neuraminidase activity. The substrate 2 -(4-methylumbelliferyl)-alpha-D-acetylneura...


Bioorg Med Chem 7: 2487-97 (1999)


Article DOI: 10.1021/jm061112p
BindingDB Entry DOI: 10.7270/Q2Z036CV
More data for this
Ligand-Target Pair
Neuraminidase A


(Influenza A virus (N9))
BDBM5269
PNG
(4-(N-Acetylamino) -3- (3- pentyloxy)benzoic acid |...)
Show SMILES CCC(CC)Oc1cc(ccc1NC(C)=O)C(O)=O
Show InChI InChI=1S/C14H19NO4/c1-4-11(5-2)19-13-8-10(14(17)18)6-7-12(13)15-9(3)16/h6-8,11H,4-5H2,1-3H3,(H,15,16)(H,17,18)
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n/an/a 3.70E+4n/an/an/an/a6.537



University of Alabama at Birmingham



Assay Description
A standard fluorimetric assay was used to measure influenza virus neuraminidase activity. The substrate 2 -(4-methylumbelliferyl)-alpha-D-acetylneura...


Bioorg Med Chem 7: 2487-97 (1999)


Article DOI: 10.1021/jm061112p
BindingDB Entry DOI: 10.7270/Q2Z036CV
More data for this
Ligand-Target Pair
Neuraminidase A


(Influenza A virus (N9))
BDBM5270
PNG
(4-(N-Acetylamino) -3- (4- heptyloxy)benzoic acid |...)
Show SMILES CCCC(CCC)Oc1cc(ccc1NC(C)=O)C(O)=O
Show InChI InChI=1S/C16H23NO4/c1-4-6-13(7-5-2)21-15-10-12(16(19)20)8-9-14(15)17-11(3)18/h8-10,13H,4-7H2,1-3H3,(H,17,18)(H,19,20)
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n/an/a 2.30E+5n/an/an/an/a6.537



University of Alabama at Birmingham



Assay Description
A standard fluorimetric assay was used to measure influenza virus neuraminidase activity. The substrate 2 -(4-methylumbelliferyl)-alpha-D-acetylneura...


Bioorg Med Chem 7: 2487-97 (1999)


Article DOI: 10.1021/jm061112p
BindingDB Entry DOI: 10.7270/Q2Z036CV
More data for this
Ligand-Target Pair
Neuraminidase A


(Influenza A virus (N9))
BDBM5271
PNG
(3-amino-4-acetamido-5-(pentan-3-yloxy)benzoic acid...)
Show SMILES CCC(CC)Oc1cc(cc(N)c1NC(C)=O)C(O)=O
Show InChI InChI=1S/C14H20N2O4/c1-4-10(5-2)20-12-7-9(14(18)19)6-11(15)13(12)16-8(3)17/h6-7,10H,4-5,15H2,1-3H3,(H,16,17)(H,18,19)
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n/an/a 1.50E+4n/an/an/an/a6.537



University of Alabama at Birmingham



Assay Description
A standard fluorimetric assay was used to measure influenza virus neuraminidase activity. The substrate 2 -(4-methylumbelliferyl)-alpha-D-acetylneura...


Bioorg Med Chem 7: 2487-97 (1999)


Article DOI: 10.1021/jm061112p
BindingDB Entry DOI: 10.7270/Q2Z036CV
More data for this
Ligand-Target Pair
Neuraminidase A


(Influenza A virus (N9))
BDBM5272
PNG
(3-carbamimidamido-4-acetamido-5-(pentan-3-yloxy)be...)
Show SMILES CCC(CC)Oc1cc(cc(N=C(N)N)c1NC(C)=O)C(O)=O
Show InChI InChI=1S/C15H22N4O4/c1-4-10(5-2)23-12-7-9(14(21)22)6-11(19-15(16)17)13(12)18-8(3)20/h6-7,10H,4-5H2,1-3H3,(H,18,20)(H,21,22)(H4,16,17,19)
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n/an/a 3.00E+3n/an/an/an/a6.537



University of Alabama at Birmingham



Assay Description
A standard fluorimetric assay was used to measure influenza virus neuraminidase activity. The substrate 2 -(4-methylumbelliferyl)-alpha-D-acetylneura...


Bioorg Med Chem 7: 2487-97 (1999)


Article DOI: 10.1021/jm061112p
BindingDB Entry DOI: 10.7270/Q2Z036CV
More data for this
Ligand-Target Pair
Neuraminidase A


(Influenza A virus (A/Singapore/1/57(H2N2)))
BDBM5269
PNG
(4-(N-Acetylamino) -3- (3- pentyloxy)benzoic acid |...)
Show SMILES CCC(CC)Oc1cc(ccc1NC(C)=O)C(O)=O
Show InChI InChI=1S/C14H19NO4/c1-4-11(5-2)19-13-8-10(14(17)18)6-7-12(13)15-9(3)16/h6-8,11H,4-5H2,1-3H3,(H,15,16)(H,17,18)
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n/an/a 1.50E+4n/an/an/an/a6.537



University of Alabama at Birmingham



Assay Description
A standard fluorimetric assay was used to measure influenza virus neuraminidase activity. The substrate 2 -(4-methylumbelliferyl)-alpha-D-acetylneura...


Bioorg Med Chem 7: 2487-97 (1999)


Article DOI: 10.1021/jm061112p
BindingDB Entry DOI: 10.7270/Q2Z036CV
More data for this
Ligand-Target Pair
Neuraminidase A


(Influenza A virus (A/Singapore/1/57(H2N2)))
BDBM5271
PNG
(3-amino-4-acetamido-5-(pentan-3-yloxy)benzoic acid...)
Show SMILES CCC(CC)Oc1cc(cc(N)c1NC(C)=O)C(O)=O
Show InChI InChI=1S/C14H20N2O4/c1-4-10(5-2)20-12-7-9(14(18)19)6-11(15)13(12)16-8(3)17/h6-7,10H,4-5,15H2,1-3H3,(H,16,17)(H,18,19)
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n/an/a 8.00E+3n/an/an/an/a6.537



University of Alabama at Birmingham



Assay Description
A standard fluorimetric assay was used to measure influenza virus neuraminidase activity. The substrate 2 -(4-methylumbelliferyl)-alpha-D-acetylneura...


Bioorg Med Chem 7: 2487-97 (1999)


Article DOI: 10.1021/jm061112p
BindingDB Entry DOI: 10.7270/Q2Z036CV
More data for this
Ligand-Target Pair
Neuraminidase A


(Influenza A virus (A/Singapore/1/57(H2N2)))
BDBM5272
PNG
(3-carbamimidamido-4-acetamido-5-(pentan-3-yloxy)be...)
Show SMILES CCC(CC)Oc1cc(cc(N=C(N)N)c1NC(C)=O)C(O)=O
Show InChI InChI=1S/C15H22N4O4/c1-4-10(5-2)23-12-7-9(14(21)22)6-11(19-15(16)17)13(12)18-8(3)20/h6-7,10H,4-5H2,1-3H3,(H,18,20)(H,21,22)(H4,16,17,19)
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n/an/a 1.00E+3n/an/an/an/a6.537



University of Alabama at Birmingham



Assay Description
A standard fluorimetric assay was used to measure influenza virus neuraminidase activity. The substrate 2 -(4-methylumbelliferyl)-alpha-D-acetylneura...


Bioorg Med Chem 7: 2487-97 (1999)


Article DOI: 10.1021/jm061112p
BindingDB Entry DOI: 10.7270/Q2Z036CV
More data for this
Ligand-Target Pair
Neuraminidase A


(Influenza A virus (A/Singapore/1/57(H2N2)))
BDBM5273
PNG
(4-acetamido-3-hydroxybenzoic acid | BANA 101)
Show SMILES CC(=O)Nc1ccc(cc1O)C(O)=O
Show InChI InChI=1S/C9H9NO4/c1-5(11)10-7-3-2-6(9(13)14)4-8(7)12/h2-4,12H,1H3,(H,10,11)(H,13,14)
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n/an/a>1.00E+7n/an/an/an/a6.537



University of Alabama at Birmingham



Assay Description
A standard fluorimetric assay was used to measure influenza virus neuraminidase activity. The substrate 2 -(4-methylumbelliferyl)-alpha-D-acetylneura...


Bioorg Med Chem 7: 2487-97 (1999)


Article DOI: 10.1021/jm061112p
BindingDB Entry DOI: 10.7270/Q2Z036CV
More data for this
Ligand-Target Pair
Neuraminidase A


(Influenza A virus (A/Singapore/1/57(H2N2)))
BDBM5274
PNG
(3-amino-4-acetamidobenzoic acid | BANA 108 | CHEMB...)
Show SMILES CC(=O)Nc1ccc(cc1N)C(O)=O
Show InChI InChI=1S/C9H10N2O3/c1-5(12)11-8-3-2-6(9(13)14)4-7(8)10/h2-4H,10H2,1H3,(H,11,12)(H,13,14)
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n/an/a>1.00E+7n/an/an/an/a6.537



University of Alabama at Birmingham



Assay Description
A standard fluorimetric assay was used to measure influenza virus neuraminidase activity. The substrate 2 -(4-methylumbelliferyl)-alpha-D-acetylneura...


Bioorg Med Chem 7: 2487-97 (1999)


Article DOI: 10.1021/jm061112p
BindingDB Entry DOI: 10.7270/Q2Z036CV
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Neuraminidase A


(Influenza A virus (A/Singapore/1/57(H2N2)))
BDBM4707
PNG
(3-(2,2-diaminoimino)-4-methylcarboxamidobenzoate |...)
Show SMILES CC(=O)Nc1ccc(cc1N=C(N)N)C(O)=O
Show InChI InChI=1S/C10H12N4O3/c1-5(15)13-7-3-2-6(9(16)17)4-8(7)14-10(11)12/h2-4H,1H3,(H,13,15)(H,16,17)(H4,11,12,14)
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n/an/a 1.00E+4n/an/an/an/a6.537



University of Alabama at Birmingham



Assay Description
A standard fluorimetric assay was used to measure influenza virus neuraminidase activity. The substrate 2 -(4-methylumbelliferyl)-alpha-D-acetylneura...


Bioorg Med Chem 7: 2487-97 (1999)


Article DOI: 10.1021/jm061112p
BindingDB Entry DOI: 10.7270/Q2Z036CV
More data for this
Ligand-Target Pair
Neuraminidase A


(Influenza A virus (N9))
BDBM4707
PNG
(3-(2,2-diaminoimino)-4-methylcarboxamidobenzoate |...)
Show SMILES CC(=O)Nc1ccc(cc1N=C(N)N)C(O)=O
Show InChI InChI=1S/C10H12N4O3/c1-5(15)13-7-3-2-6(9(16)17)4-8(7)14-10(11)12/h2-4H,1H3,(H,13,15)(H,16,17)(H4,11,12,14)
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n/an/a 1.00E+4n/an/an/an/a6.537



University of Alabama at Birmingham



Assay Description
A standard fluorimetric assay was used to measure influenza virus neuraminidase activity. The substrate 2 -(4-methylumbelliferyl)-alpha-D-acetylneura...


Bioorg Med Chem Lett 9: 1901-6 (1999)


Article DOI: 10.1016/s0960-894x(99)00318-2
BindingDB Entry DOI: 10.7270/Q2T72FN4
More data for this
Ligand-Target Pair
Neuraminidase A


(Influenza A virus (N9))
BDBM4723
PNG
(3,5-dicarbamimidamido-4-acetamidobenzoic acid | Be...)
Show SMILES CC(=O)Nc1c(cc(cc1N=C(N)N)C(O)=O)N=C(N)N
Show InChI InChI=1S/C11H15N7O3/c1-4(19)16-8-6(17-10(12)13)2-5(9(20)21)3-7(8)18-11(14)15/h2-3H,1H3,(H,16,19)(H,20,21)(H4,12,13,17)(H4,14,15,18)
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n/an/a 2.50E+5n/an/an/an/a6.537



University of Alabama at Birmingham



Assay Description
A standard fluorimetric assay was used to measure influenza virus neuraminidase activity. The substrate 2 -(4-methylumbelliferyl)-alpha-D-acetylneura...


Bioorg Med Chem Lett 9: 1901-6 (1999)


Article DOI: 10.1016/s0960-894x(99)00318-2
BindingDB Entry DOI: 10.7270/Q2T72FN4
More data for this
Ligand-Target Pair
Neuraminidase A


(Influenza A virus (N9))
BDBM5278
PNG
(3-carbamimidamido-4-(2-oxopyrrolidin-1-yl)benzoic ...)
Show SMILES NC(=N)Nc1cc(ccc1N1CCCC1=O)C(O)=O
Show InChI InChI=1S/C12H14N4O3/c13-12(14)15-8-6-7(11(18)19)3-4-9(8)16-5-1-2-10(16)17/h3-4,6H,1-2,5H2,(H,18,19)(H4,13,14,15)
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n/an/a 2.50E+5n/an/an/an/a6.537



University of Alabama at Birmingham



Assay Description
A standard fluorimetric assay was used to measure influenza virus neuraminidase activity. The substrate 2 -(4-methylumbelliferyl)-alpha-D-acetylneura...


Bioorg Med Chem Lett 9: 1901-6 (1999)


Article DOI: 10.1016/s0960-894x(99)00318-2
BindingDB Entry DOI: 10.7270/Q2T72FN4
More data for this
Ligand-Target Pair
Neuraminidase A


(Influenza A virus (N9))
BDBM5279
PNG
(3-carbamimidamido-4-[2-(hydroxymethyl)-5-oxopyrrol...)
Show SMILES NC(=N)Nc1cc(ccc1N1C(CO)CCC1=O)C(O)=O
Show InChI InChI=1S/C13H16N4O4/c14-13(15)16-9-5-7(12(20)21)1-3-10(9)17-8(6-18)2-4-11(17)19/h1,3,5,8,18H,2,4,6H2,(H,20,21)(H4,14,15,16)
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n/an/a 2.00E+4n/an/an/an/a6.537



University of Alabama at Birmingham



Assay Description
A standard fluorimetric assay was used to measure influenza virus neuraminidase activity. The substrate 2 -(4-methylumbelliferyl)-alpha-D-acetylneura...


Bioorg Med Chem Lett 9: 1901-6 (1999)


Article DOI: 10.1016/s0960-894x(99)00318-2
BindingDB Entry DOI: 10.7270/Q2T72FN4
More data for this
Ligand-Target Pair
Neuraminidase A


(Influenza A virus (N9))
BDBM4701
PNG
(4-benzamidobenzoic acid | Benzoic Acid deriv. 14)
Show SMILES OC(=O)c1ccc(NC(=O)c2ccccc2)cc1
Show InChI InChI=1S/C14H11NO3/c16-13(10-4-2-1-3-5-10)15-12-8-6-11(7-9-12)14(17)18/h1-9H,(H,15,16)(H,17,18)
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n/an/a 1.50E+6n/an/an/an/a6.537



BioCryst Pharmaceuticals, Inc.



Assay Description
A standard fluorimetric assay was used to measure influenza virus neuraminidase activity. The substrate 2 -(4-methylumbelliferyl)-alpha-D-acetylneura...


J Med Chem 40: 4030-52 (1997)


Article DOI: 10.1021/jm970479e
BindingDB Entry DOI: 10.7270/Q2X63K41
More data for this
Ligand-Target Pair
Neuraminidase A


(Influenza A virus (N9))
BDBM4703
PNG
(4-carboxybenzenesulfonamide 1 | 4-sulfamoylbenzoic...)
Show SMILES NS(=O)(=O)c1ccc(cc1)C(O)=O
Show InChI InChI=1S/C7H7NO4S/c8-13(11,12)6-3-1-5(2-4-6)7(9)10/h1-4H,(H,9,10)(H2,8,11,12)
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n/an/a 2.50E+6n/an/an/an/a6.537



BioCryst Pharmaceuticals, Inc.



Assay Description
A standard fluorimetric assay was used to measure influenza virus neuraminidase activity. The substrate 2 -(4-methylumbelliferyl)-alpha-D-acetylneura...


J Med Chem 40: 4030-52 (1997)


Article DOI: 10.1021/jm970479e
BindingDB Entry DOI: 10.7270/Q2X63K41
More data for this
Ligand-Target Pair
Neuraminidase A


(Influenza A virus (N9))
BDBM4704
PNG
(3-(Cyanoamino)benzoic Acid | Benzoic Acid deriv. 6...)
Show SMILES OC(=O)c1cccc(NC#N)c1
Show InChI InChI=1S/C8H6N2O2/c9-5-10-7-3-1-2-6(4-7)8(11)12/h1-4,10H,(H,11,12)
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n/an/a 4.00E+6n/an/an/an/a6.537



BioCryst Pharmaceuticals, Inc.



Assay Description
A standard fluorimetric assay was used to measure influenza virus neuraminidase activity. The substrate 2 -(4-methylumbelliferyl)-alpha-D-acetylneura...


J Med Chem 40: 4030-52 (1997)


Article DOI: 10.1021/jm970479e
BindingDB Entry DOI: 10.7270/Q2X63K41
More data for this
Ligand-Target Pair
Neuraminidase A


(Influenza A virus (N9))
BDBM4705
PNG
(3-carbamimidamidobenzoic acid | Benzoic Acid deriv...)
Show SMILES NC(N)=Nc1cccc(c1)C(O)=O
Show InChI InChI=1S/C8H9N3O2/c9-8(10)11-6-3-1-2-5(4-6)7(12)13/h1-4H,(H,12,13)(H4,9,10,11)
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n/an/a 5.00E+6n/an/an/an/a6.537



BioCryst Pharmaceuticals, Inc.



Assay Description
A standard fluorimetric assay was used to measure influenza virus neuraminidase activity. The substrate 2 -(4-methylumbelliferyl)-alpha-D-acetylneura...


J Med Chem 40: 4030-52 (1997)


Article DOI: 10.1021/jm970479e
BindingDB Entry DOI: 10.7270/Q2X63K41
More data for this
Ligand-Target Pair
Neuraminidase A


(Influenza A virus (N9))
BDBM4706
PNG
((2R,3R,4S)-3-acetamido-4-hydroxy-2-[(1R,2R)-1,2,3-...)
Show SMILES CC(=O)N[C@@H]1[C@@H](O)C=C(O[C@H]1[C@H](O)[C@H](O)CO)C(O)=O
Show InChI InChI=1S/C11H17NO8/c1-4(14)12-8-5(15)2-7(11(18)19)20-10(8)9(17)6(16)3-13/h2,5-6,8-10,13,15-17H,3H2,1H3,(H,12,14)(H,18,19)/t5-,6+,8+,9+,10+/m0/s1
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PubMed
n/an/a 1.30E+4n/an/an/an/a6.537



BioCryst Pharmaceuticals, Inc.



Assay Description
A standard fluorimetric assay was used to measure influenza virus neuraminidase activity. The substrate 2 -(4-methylumbelliferyl)-alpha-D-acetylneura...


J Med Chem 40: 4030-52 (1997)


Article DOI: 10.1021/jm970479e
BindingDB Entry DOI: 10.7270/Q2X63K41
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Neuraminidase A


(Influenza A virus (N9))
BDBM4707
PNG
(3-(2,2-diaminoimino)-4-methylcarboxamidobenzoate |...)
Show SMILES CC(=O)Nc1ccc(cc1N=C(N)N)C(O)=O
Show InChI InChI=1S/C10H12N4O3/c1-5(15)13-7-3-2-6(9(16)17)4-8(7)14-10(11)12/h2-4H,1H3,(H,13,15)(H,16,17)(H4,11,12,14)
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n/an/a 2.50E+3n/an/an/an/a6.537



BioCryst Pharmaceuticals, Inc.



Assay Description
A standard fluorimetric assay was used to measure influenza virus neuraminidase activity. The substrate 2 -(4-methylumbelliferyl)-alpha-D-acetylneura...


J Med Chem 40: 4030-52 (1997)


Article DOI: 10.1021/jm970479e
BindingDB Entry DOI: 10.7270/Q2X63K41
More data for this
Ligand-Target Pair
Neuraminidase A


(Influenza A virus (N9))
BDBM4708
PNG
(4-(Acetylamino)-3-[(hydroxyimino)methyl]benzoic Ac...)
Show SMILES CC(=O)Nc1ccc(cc1CN=O)C(O)=O
Show InChI InChI=1S/C10H10N2O4/c1-6(13)12-9-3-2-7(10(14)15)4-8(9)5-11-16/h2-4H,5H2,1H3,(H,12,13)(H,14,15)
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n/an/a 5.50E+6n/an/an/an/a6.537



BioCryst Pharmaceuticals, Inc.



Assay Description
A standard fluorimetric assay was used to measure influenza virus neuraminidase activity. The substrate 2 -(4-methylumbelliferyl)-alpha-D-acetylneura...


J Med Chem 40: 4030-52 (1997)


Article DOI: 10.1021/jm970479e
BindingDB Entry DOI: 10.7270/Q2X63K41
More data for this
Ligand-Target Pair
Neuraminidase A


(Influenza A virus (N9))
BDBM4709
PNG
(4-(Acetylamino)-3-(2-nitroethyl)benzoic Acid | 4-a...)
Show SMILES CC(=O)Nc1ccc(cc1CC[N+]([O-])=O)C(O)=O
Show InChI InChI=1S/C11H12N2O5/c1-7(14)12-10-3-2-9(11(15)16)6-8(10)4-5-13(17)18/h2-3,6H,4-5H2,1H3,(H,12,14)(H,15,16)
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n/an/a 2.50E+6n/an/an/an/a6.537



BioCryst Pharmaceuticals, Inc.



Assay Description
A standard fluorimetric assay was used to measure influenza virus neuraminidase activity. The substrate 2 -(4-methylumbelliferyl)-alpha-D-acetylneura...


J Med Chem 40: 4030-52 (1997)


Article DOI: 10.1021/jm970479e
BindingDB Entry DOI: 10.7270/Q2X63K41
More data for this
Ligand-Target Pair
Neuraminidase A


(Influenza A virus (N9))
BDBM4710
PNG
(3-[(Aminoiminomethyl)amino]-4-[(methylsulfonyl)ami...)
Show SMILES CS(=O)(=O)Nc1ccc(cc1N=C(N)N)C(O)=O
Show InChI InChI=1S/C9H12N4O4S/c1-18(16,17)13-6-3-2-5(8(14)15)4-7(6)12-9(10)11/h2-4,13H,1H3,(H,14,15)(H4,10,11,12)
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n/an/a 1.00E+5n/an/an/an/a6.537



BioCryst Pharmaceuticals, Inc.



Assay Description
A standard fluorimetric assay was used to measure influenza virus neuraminidase activity. The substrate 2 -(4-methylumbelliferyl)-alpha-D-acetylneura...


J Med Chem 40: 4030-52 (1997)


Article DOI: 10.1021/jm970479e
BindingDB Entry DOI: 10.7270/Q2X63K41
More data for this
Ligand-Target Pair
Neuraminidase A


(Influenza A virus (N9))
BDBM4711
PNG
(3-[(1E)-(hydroxyimino)methyl]-4-methanesulfonamido...)
Show SMILES CS(=O)(=O)Nc1ccc(cc1CN=O)C(O)=O
Show InChI InChI=1S/C9H10N2O5S/c1-17(15,16)11-8-3-2-6(9(12)13)4-7(8)5-10-14/h2-4,11H,5H2,1H3,(H,12,13)
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n/an/a 2.00E+6n/an/an/an/a6.537



BioCryst Pharmaceuticals, Inc.



Assay Description
A standard fluorimetric assay was used to measure influenza virus neuraminidase activity. The substrate 2 -(4-methylumbelliferyl)-alpha-D-acetylneura...


J Med Chem 40: 4030-52 (1997)


Article DOI: 10.1021/jm970479e
BindingDB Entry DOI: 10.7270/Q2X63K41
More data for this
Ligand-Target Pair
Neuraminidase A


(Influenza A virus (N9))
BDBM4712
PNG
(3-[(Aminoiminomethyl)amino]-4-[(2-methylpropionyl)...)
Show SMILES CC(C)C(=O)Nc1ccc(cc1N=C(N)N)C(O)=O
Show InChI InChI=1S/C12H16N4O3/c1-6(2)10(17)15-8-4-3-7(11(18)19)5-9(8)16-12(13)14/h3-6H,1-2H3,(H,15,17)(H,18,19)(H4,13,14,16)
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n/an/a 1.00E+6n/an/an/an/a6.537



BioCryst Pharmaceuticals, Inc.



Assay Description
A standard fluorimetric assay was used to measure influenza virus neuraminidase activity. The substrate 2 -(4-methylumbelliferyl)-alpha-D-acetylneura...


J Med Chem 40: 4030-52 (1997)


Article DOI: 10.1021/jm970479e
BindingDB Entry DOI: 10.7270/Q2X63K41
More data for this
Ligand-Target Pair
Neuraminidase A


(Influenza A virus (N9))
BDBM4713
PNG
(3-[(Aminoiminomethyl)amino]-4-[(methylamino)carbon...)
Show SMILES CNC(=O)c1ccc(cc1N=C(N)N)C(O)=O
Show InChI InChI=1S/C10H12N4O3/c1-13-8(15)6-3-2-5(9(16)17)4-7(6)14-10(11)12/h2-4H,1H3,(H,13,15)(H,16,17)(H4,11,12,14)
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n/an/a 5.00E+3n/an/an/an/a6.537



BioCryst Pharmaceuticals, Inc.



Assay Description
A standard fluorimetric assay was used to measure influenza virus neuraminidase activity. The substrate 2 -(4-methylumbelliferyl)-alpha-D-acetylneura...


J Med Chem 40: 4030-52 (1997)


Article DOI: 10.1021/jm970479e
BindingDB Entry DOI: 10.7270/Q2X63K41
More data for this
Ligand-Target Pair
Neuraminidase A


(Influenza A virus (N9))
BDBM4714
PNG
(3-[(Aminoiminomethyl)amino]-4-(aminosulfonyl)benzo...)
Show SMILES NC(N)=Nc1cc(ccc1S(N)(=O)=O)C(O)=O
Show InChI InChI=1S/C8H10N4O4S/c9-8(10)12-5-3-4(7(13)14)1-2-6(5)17(11,15)16/h1-3H,(H,13,14)(H4,9,10,12)(H2,11,15,16)
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n/an/a 9.00E+3n/an/an/an/a6.537



BioCryst Pharmaceuticals, Inc.



Assay Description
A standard fluorimetric assay was used to measure influenza virus neuraminidase activity. The substrate 2 -(4-methylumbelliferyl)-alpha-D-acetylneura...


J Med Chem 40: 4030-52 (1997)


Article DOI: 10.1021/jm970479e
BindingDB Entry DOI: 10.7270/Q2X63K41
More data for this
Ligand-Target Pair
Neuraminidase A


(Influenza A virus (N9))
BDBM4715
PNG
(3-[(Aminoiminomethyl)amino]-4-[(methylsulfoxy)meth...)
Show SMILES CS(=O)Cc1ccc(cc1N=C(N)N)C(O)=O
Show InChI InChI=1S/C10H13N3O3S/c1-17(16)5-7-3-2-6(9(14)15)4-8(7)13-10(11)12/h2-4H,5H2,1H3,(H,14,15)(H4,11,12,13)
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n/an/a 1.40E+5n/an/an/an/a6.537



BioCryst Pharmaceuticals, Inc.



Assay Description
A standard fluorimetric assay was used to measure influenza virus neuraminidase activity. The substrate 2 -(4-methylumbelliferyl)-alpha-D-acetylneura...


J Med Chem 40: 4030-52 (1997)


Article DOI: 10.1021/jm970479e
BindingDB Entry DOI: 10.7270/Q2X63K41
More data for this
Ligand-Target Pair
Neuraminidase A


(Influenza A virus (N9))
BDBM4716
PNG
(3-[(Aminoiminomethyl)amino]-4-[(methylsulfonyl)-me...)
Show SMILES CS(=O)(=O)Cc1ccc(cc1N=C(N)N)C(O)=O
Show InChI InChI=1S/C10H13N3O4S/c1-18(16,17)5-7-3-2-6(9(14)15)4-8(7)13-10(11)12/h2-4H,5H2,1H3,(H,14,15)(H4,11,12,13)
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n/an/a 3.00E+5n/an/an/an/a6.537



BioCryst Pharmaceuticals, Inc.



Assay Description
A standard fluorimetric assay was used to measure influenza virus neuraminidase activity. The substrate 2 -(4-methylumbelliferyl)-alpha-D-acetylneura...


J Med Chem 40: 4030-52 (1997)


Article DOI: 10.1021/jm970479e
BindingDB Entry DOI: 10.7270/Q2X63K41
More data for this
Ligand-Target Pair
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