BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 463 hits of ph data with Target = 'Non-receptor tyrosine-protein kinase TYK2'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Non-receptor tyrosine-protein kinase TYK2


(Homo sapiens (Human))
BDBM81442
PNG
(CP-690,550)
Show SMILES C[C@@H]1CCC(CC1N(C)c1ncnc2[nH]ccc12)C(=O)CC#N
Show InChI InChI=1S/C17H21N5O/c1-11-3-4-12(15(23)5-7-18)9-14(11)22(2)17-13-6-8-19-16(13)20-10-21-17/h6,8,10-12,14H,3-5,9H2,1-2H3,(H,19,20,21)/t11-,12?,14?/m1/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 176n/an/an/an/a7.530



University of Luxembourg



Assay Description
Enzyme assay affinity-purified GST fusions of the active kinase domains (GST-Jak1(866-1154), GST-Jak2(808-1132), GST-Jak3(811-1124) and GST-Tyk2(888-...


Chem Biol 18: 314-23 (2011)


Article DOI: 10.1016/j.chembiol.2011.01.012
BindingDB Entry DOI: 10.7270/Q2736PDR
More data for this
Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2


(Homo sapiens (Human))
BDBM26198
PNG
(4-tert-butyl-15-fluoro-3,5,10-triazatetracyclo[11....)
Show SMILES CC(C)(C)c1nc2c([nH]1)c1ccc(F)cc1c1c2cc[nH]c1=O
Show InChI InChI=1S/C18H16FN3O/c1-18(2,3)17-21-14-10-5-4-9(19)8-12(10)13-11(15(14)22-17)6-7-20-16(13)23/h4-8H,1-3H3,(H,20,23)(H,21,22)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
Purchase

CHEMBL
MMDB
PC cid
PC sid
PDB
UniChem

Patents


Similars

PDB
Article
PubMed
n/an/a 7n/an/an/an/a7.530



University of Luxembourg



Assay Description
Enzyme assay affinity-purified GST fusions of the active kinase domains (GST-Jak1(866-1154), GST-Jak2(808-1132), GST-Jak3(811-1124) and GST-Tyk2(888-...


Chem Biol 18: 314-23 (2011)


Article DOI: 10.1016/j.chembiol.2011.01.012
BindingDB Entry DOI: 10.7270/Q2736PDR
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Non-receptor tyrosine-protein kinase TYK2


(Homo sapiens (Human))
BDBM50335231
PNG
(3-{5-[4-(2-Hydroxy-2-methyl-propionyl)-piperazin-1...)
Show SMILES CC(C)(O)C(=O)N1CCN(CC1)c1ccc(c(c1)C1=C(C(=O)NC1=O)c1c[nH]c2ccccc12)C(F)(F)F
Show InChI InChI=1S/C27H25F3N4O4/c1-26(2,38)25(37)34-11-9-33(10-12-34)15-7-8-19(27(28,29)30)17(13-15)21-22(24(36)32-23(21)35)18-14-31-20-6-4-3-5-16(18)20/h3-8,13-14,31,38H,9-12H2,1-2H3,(H,32,35,36)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 8.06E+3n/an/an/an/a7.530



University of Luxembourg



Assay Description
Enzyme assay affinity-purified GST fusions of the active kinase domains (GST-Jak1(866-1154), GST-Jak2(808-1132), GST-Jak3(811-1124) and GST-Tyk2(888-...


Chem Biol 18: 314-23 (2011)


Article DOI: 10.1016/j.chembiol.2011.01.012
BindingDB Entry DOI: 10.7270/Q2736PDR
More data for this
Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2


(Homo sapiens (Human))
BDBM198203
PNG
(US9216999, 11 | US9556187, Example 13)
Show SMILES CC1CCN(CC1c1nnn2cnc3[nH]ccc3c12)C(=O)OC(C)(C)C
Show InChI InChI=1S/C18H24N6O2/c1-11-6-8-23(17(25)26-18(2,3)4)9-13(11)14-15-12-5-7-19-16(12)20-10-24(15)22-21-14/h5,7,10-11,13,19H,6,8-9H2,1-4H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a 4.10E+3n/an/an/an/a7.5n/a



Nissan Chemical Industries, Ltd.

US Patent


Assay Description
JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...


US Patent US9216999 (2015)


BindingDB Entry DOI: 10.7270/Q28C9V2J
More data for this
Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2


(Homo sapiens (Human))
BDBM198204
PNG
(US9216999, 12 | US9556187, Example 12)
Show SMILES CC1CCN(CC1c1nnn2cnc3[nH]ccc3c12)C(=O)CC#N
Show InChI InChI=1S/C16H17N7O/c1-10-4-7-22(13(24)2-5-17)8-12(10)14-15-11-3-6-18-16(11)19-9-23(15)21-20-14/h3,6,9-10,12,18H,2,4,7-8H2,1H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a 910n/an/an/an/a7.5n/a



Nissan Chemical Industries, Ltd.

US Patent


Assay Description
JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...


US Patent US9216999 (2015)


BindingDB Entry DOI: 10.7270/Q28C9V2J
More data for this
Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2


(Homo sapiens (Human))
BDBM198205
PNG
(US9216999, 13)
Show SMILES CC(C)(C)OC(=O)N1CCCC(C1)c1nnn2cnc3[nH]ccc3c12
Show InChI InChI=1S/C17H22N6O2/c1-17(2,3)25-16(24)22-8-4-5-11(9-22)13-14-12-6-7-18-15(12)19-10-23(14)21-20-13/h6-7,10-11,18H,4-5,8-9H2,1-3H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a>1.00E+3n/an/an/an/a7.5n/a



Nissan Chemical Industries, Ltd.

US Patent


Assay Description
JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...


US Patent US9216999 (2015)


BindingDB Entry DOI: 10.7270/Q28C9V2J
More data for this
Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2


(Homo sapiens (Human))
BDBM198206
PNG
(US9216999, 14 | US9556187, Example 14)
Show SMILES O=C(OCc1ccccc1)N1CCCC(C1)c1nnn2cnc3[nH]ccc3c12
Show InChI InChI=1S/C20H20N6O2/c27-20(28-12-14-5-2-1-3-6-14)25-10-4-7-15(11-25)17-18-16-8-9-21-19(16)22-13-26(18)24-23-17/h1-3,5-6,8-9,13,15,21H,4,7,10-12H2
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a 2.20E+3n/an/an/an/a7.5n/a



Nissan Chemical Industries, Ltd.

US Patent


Assay Description
JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...


US Patent US9216999 (2015)


BindingDB Entry DOI: 10.7270/Q28C9V2J
More data for this
Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2


(Homo sapiens (Human))
BDBM198207
PNG
(US9216999, 15 | US9556187, Example 15)
Show SMILES C1CNCC(C1)c1nnn2cnc3[nH]ccc3c12
Show InChI InChI=1S/C12H14N6/c1-2-8(6-13-4-1)10-11-9-3-5-14-12(9)15-7-18(11)17-16-10/h3,5,7-8,13-14H,1-2,4,6H2
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a>1.00E+3n/an/an/an/a7.5n/a



Nissan Chemical Industries, Ltd.

US Patent


Assay Description
JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...


US Patent US9216999 (2015)


BindingDB Entry DOI: 10.7270/Q28C9V2J
More data for this
Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2


(Homo sapiens (Human))
BDBM198208
PNG
(US9216999, 16 | US9556187, Example 16)
Show SMILES C(N1CCCC(C1)c1nnn2cnc3[nH]ccc3c12)c1ccccc1
Show InChI InChI=1S/C19H20N6/c1-2-5-14(6-3-1)11-24-10-4-7-15(12-24)17-18-16-8-9-20-19(16)21-13-25(18)23-22-17/h1-3,5-6,8-9,13,15,20H,4,7,10-12H2
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a 2.60E+3n/an/an/an/a7.5n/a



Nissan Chemical Industries, Ltd.

US Patent


Assay Description
JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...


US Patent US9216999 (2015)


BindingDB Entry DOI: 10.7270/Q28C9V2J
More data for this
Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2


(Homo sapiens (Human))
BDBM198209
PNG
(US9216999, 17 | US9556187, Example 17)
Show SMILES FC(F)(F)CC(=O)N1CCCC(C1)c1nnn2cnc3[nH]ccc3c12
Show InChI InChI=1S/C15H15F3N6O/c16-15(17,18)6-11(25)23-5-1-2-9(7-23)12-13-10-3-4-19-14(10)20-8-24(13)22-21-12/h3-4,8-9,19H,1-2,5-7H2
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a 570n/an/an/an/a7.5n/a



Nissan Chemical Industries, Ltd.

US Patent


Assay Description
JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...


US Patent US9216999 (2015)


BindingDB Entry DOI: 10.7270/Q28C9V2J
More data for this
Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2


(Homo sapiens (Human))
BDBM198210
PNG
(US9216999, 18 | US9556187, Example 18)
Show SMILES C(N1CCCC(C1)c1nnn2cnc3[nH]ccc3c12)c1cccnc1
Show InChI InChI=1S/C18H19N7/c1-3-13(9-19-6-1)10-24-8-2-4-14(11-24)16-17-15-5-7-20-18(15)21-12-25(17)23-22-16/h1,3,5-7,9,12,14,20H,2,4,8,10-11H2
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a>1.00E+3n/an/an/an/a7.5n/a



Nissan Chemical Industries, Ltd.

US Patent


Assay Description
JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...


US Patent US9216999 (2015)


BindingDB Entry DOI: 10.7270/Q28C9V2J
More data for this
Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2


(Homo sapiens (Human))
BDBM198211
PNG
(US9216999, 19 | US9556187, Example 19)
Show SMILES C(N1CCCC(C1)c1nnn2cnc3[nH]ccc3c12)c1cncs1
Show InChI InChI=1S/C16H17N7S/c1-2-11(7-22(5-1)8-12-6-17-10-24-12)14-15-13-3-4-18-16(13)19-9-23(15)21-20-14/h3-4,6,9-11,18H,1-2,5,7-8H2
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a 1.00E+3n/an/an/an/a7.5n/a



Nissan Chemical Industries, Ltd.

US Patent


Assay Description
JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...


US Patent US9216999 (2015)


BindingDB Entry DOI: 10.7270/Q28C9V2J
More data for this
Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2


(Homo sapiens (Human))
BDBM198212
PNG
(US9216999, 20 | US9556187, Example 20)
Show SMILES O=C(Nc1nncs1)N1CCCC(C1)c1nnn2cnc3[nH]ccc3c12
Show InChI InChI=1S/C15H15N9OS/c25-15(19-14-21-18-8-26-14)23-5-1-2-9(6-23)11-12-10-3-4-16-13(10)17-7-24(12)22-20-11/h3-4,7-9,16H,1-2,5-6H2,(H,19,21,25)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a 420n/an/an/an/a7.5n/a



Nissan Chemical Industries, Ltd.

US Patent


Assay Description
JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...


US Patent US9216999 (2015)


BindingDB Entry DOI: 10.7270/Q28C9V2J
More data for this
Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2


(Homo sapiens (Human))
BDBM198213
PNG
(US9216999, 21 | US9556187, Example 21)
Show SMILES Cc1cc(NC(=O)N2CCCC(C2)c2nnn3cnc4[nH]ccc4c23)sn1
Show InChI InChI=1S/C17H18N8OS/c1-10-7-13(27-22-10)20-17(26)24-6-2-3-11(8-24)14-15-12-4-5-18-16(12)19-9-25(15)23-21-14/h4-5,7,9,11,18H,2-3,6,8H2,1H3,(H,20,26)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a 710n/an/an/an/a7.5n/a



Nissan Chemical Industries, Ltd.

US Patent


Assay Description
JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...


US Patent US9216999 (2015)


BindingDB Entry DOI: 10.7270/Q28C9V2J
More data for this
Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2


(Homo sapiens (Human))
BDBM198214
PNG
(US9216999, 22 | US9556187, Example 22)
Show SMILES N#Cc1ccc(CN2CCCC(C2)c2nnn3cnc4[nH]ccc4c23)cc1
Show InChI InChI=1S/C20H19N7/c21-10-14-3-5-15(6-4-14)11-26-9-1-2-16(12-26)18-19-17-7-8-22-20(17)23-13-27(19)25-24-18/h3-8,13,16,22H,1-2,9,11-12H2
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a 880n/an/an/an/a7.5n/a



Nissan Chemical Industries, Ltd.

US Patent


Assay Description
JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...


US Patent US9216999 (2015)


BindingDB Entry DOI: 10.7270/Q28C9V2J
More data for this
Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2


(Homo sapiens (Human))
BDBM198215
PNG
(US9216999, 23 | US9556187, Example 23)
Show SMILES FC(F)(F)c1ccc(CN2CCCC(C2)c2nnn3cnc4[nH]ccc4c23)cc1
Show InChI InChI=1S/C20H19F3N6/c21-20(22,23)15-5-3-13(4-6-15)10-28-9-1-2-14(11-28)17-18-16-7-8-24-19(16)25-12-29(18)27-26-17/h3-8,12,14,24H,1-2,9-11H2
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a>1.00E+3n/an/an/an/a7.5n/a



Nissan Chemical Industries, Ltd.

US Patent


Assay Description
JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...


US Patent US9216999 (2015)


BindingDB Entry DOI: 10.7270/Q28C9V2J
More data for this
Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2


(Homo sapiens (Human))
BDBM198216
PNG
(US9216999, 24 | US9556187, Example 24)
Show SMILES CC(C)(C)OC(=O)N1CCC(CC1)c1nnn2cnc3[nH]ccc3c12
Show InChI InChI=1S/C17H22N6O2/c1-17(2,3)25-16(24)22-8-5-11(6-9-22)13-14-12-4-7-18-15(12)19-10-23(14)21-20-13/h4,7,10-11,18H,5-6,8-9H2,1-3H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a 5.30E+3n/an/an/an/a7.5n/a



Nissan Chemical Industries, Ltd.

US Patent


Assay Description
JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...


US Patent US9216999 (2015)


BindingDB Entry DOI: 10.7270/Q28C9V2J
More data for this
Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2


(Homo sapiens (Human))
BDBM198217
PNG
(US9216999, 25 | US9556187, Example 25)
Show SMILES FC(F)(F)CN1CCC(CC1)c1nnn2cnc3[nH]ccc3c12
Show InChI InChI=1S/C14H15F3N6/c15-14(16,17)7-22-5-2-9(3-6-22)11-12-10-1-4-18-13(10)19-8-23(12)21-20-11/h1,4,8-9,18H,2-3,5-7H2
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a 160n/an/an/an/a7.5n/a



Nissan Chemical Industries, Ltd.

US Patent


Assay Description
JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...


US Patent US9216999 (2015)


BindingDB Entry DOI: 10.7270/Q28C9V2J
More data for this
Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2


(Homo sapiens (Human))
BDBM198218
PNG
(US9216999, 26 | US9556187, Example 84)
Show SMILES O=C(OCc1ccccc1)N1CCC(CC1)c1nnn2cnc3[nH]ccc3c12
Show InChI InChI=1S/C20H20N6O2/c27-20(28-12-14-4-2-1-3-5-14)25-10-7-15(8-11-25)17-18-16-6-9-21-19(16)22-13-26(18)24-23-17/h1-6,9,13,15,21H,7-8,10-12H2
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a>1.00E+3n/an/an/an/a7.5n/a



Nissan Chemical Industries, Ltd.

US Patent


Assay Description
JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...


US Patent US9216999 (2015)


BindingDB Entry DOI: 10.7270/Q28C9V2J
More data for this
Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2


(Homo sapiens (Human))
BDBM198219
PNG
(US9216999, 27 | US9556187, Example 27)
Show SMILES C1CC(CCN1)c1nnn2cnc3[nH]ccc3c12
Show InChI InChI=1S/C12H14N6/c1-4-13-5-2-8(1)10-11-9-3-6-14-12(9)15-7-18(11)17-16-10/h3,6-8,13-14H,1-2,4-5H2
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a>1.00E+3n/an/an/an/a7.5n/a



Nissan Chemical Industries, Ltd.

US Patent


Assay Description
JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...


US Patent US9216999 (2015)


BindingDB Entry DOI: 10.7270/Q28C9V2J
More data for this
Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2


(Homo sapiens (Human))
BDBM198220
PNG
(US9216999, 28 | US9556187, Example 28)
Show SMILES C(N1CCC(CC1)c1nnn2cnc3[nH]ccc3c12)c1cccnc1
Show InChI InChI=1S/C18H19N7/c1-2-13(10-19-6-1)11-24-8-4-14(5-9-24)16-17-15-3-7-20-18(15)21-12-25(17)23-22-16/h1-3,6-7,10,12,14,20H,4-5,8-9,11H2
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a 1.50E+3n/an/an/an/a7.5n/a



Nissan Chemical Industries, Ltd.

US Patent


Assay Description
JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...


US Patent US9216999 (2015)


BindingDB Entry DOI: 10.7270/Q28C9V2J
More data for this
Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2


(Homo sapiens (Human))
BDBM198221
PNG
(US9216999, 29 | US9556187, Example 29)
Show SMILES FC(F)(F)CC(=O)N1CCC(CC1)c1nnn2cnc3[nH]ccc3c12
Show InChI InChI=1S/C15H15F3N6O/c16-15(17,18)7-11(25)23-5-2-9(3-6-23)12-13-10-1-4-19-14(10)20-8-24(13)22-21-12/h1,4,8-9,19H,2-3,5-7H2
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a>1.00E+3n/an/an/an/a7.5n/a



Nissan Chemical Industries, Ltd.

US Patent


Assay Description
JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...


US Patent US9216999 (2015)


BindingDB Entry DOI: 10.7270/Q28C9V2J
More data for this
Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2


(Homo sapiens (Human))
BDBM198222
PNG
(US9216999, 30 | US9556187, Example 30)
Show SMILES O=C(Nc1nncs1)N1CCC(CC1)c1nnn2cnc3[nH]ccc3c12
Show InChI InChI=1S/C15H15N9OS/c25-15(19-14-21-18-8-26-14)23-5-2-9(3-6-23)11-12-10-1-4-16-13(10)17-7-24(12)22-20-11/h1,4,7-9,16H,2-3,5-6H2,(H,19,21,25)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a 200n/an/an/an/a7.5n/a



Nissan Chemical Industries, Ltd.

US Patent


Assay Description
JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...


US Patent US9216999 (2015)


BindingDB Entry DOI: 10.7270/Q28C9V2J
More data for this
Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2


(Homo sapiens (Human))
BDBM198223
PNG
(US9216999, 31 | US9556187, Example 31)
Show SMILES Cc1cc(NC(=O)N2CCC(CC2)c2nnn3cnc4[nH]ccc4c23)sn1
Show InChI InChI=1S/C17H18N8OS/c1-10-8-13(27-22-10)20-17(26)24-6-3-11(4-7-24)14-15-12-2-5-18-16(12)19-9-25(15)23-21-14/h2,5,8-9,11,18H,3-4,6-7H2,1H3,(H,20,26)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a>1.00E+3n/an/an/an/a7.5n/a



Nissan Chemical Industries, Ltd.

US Patent


Assay Description
JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...


US Patent US9216999 (2015)


BindingDB Entry DOI: 10.7270/Q28C9V2J
More data for this
Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2


(Homo sapiens (Human))
BDBM198224
PNG
(US9216999, 32 | US9556187, Example 32)
Show SMILES C(N1CCC(CC1)c1nnn2cnc3[nH]ccc3c12)c1ccccc1
Show InChI InChI=1S/C19H20N6/c1-2-4-14(5-3-1)12-24-10-7-15(8-11-24)17-18-16-6-9-20-19(16)21-13-25(18)23-22-17/h1-6,9,13,15,20H,7-8,10-12H2
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a 990n/an/an/an/a7.5n/a



Nissan Chemical Industries, Ltd.

US Patent


Assay Description
JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...


US Patent US9216999 (2015)


BindingDB Entry DOI: 10.7270/Q28C9V2J
More data for this
Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2


(Homo sapiens (Human))
BDBM198225
PNG
(US9216999, 33 | US9556187, Example 33)
Show SMILES FC(F)(F)c1ccc(CN2CCC(CC2)c2nnn3cnc4[nH]ccc4c23)cc1
Show InChI InChI=1S/C20H19F3N6/c21-20(22,23)15-3-1-13(2-4-15)11-28-9-6-14(7-10-28)17-18-16-5-8-24-19(16)25-12-29(18)27-26-17/h1-5,8,12,14,24H,6-7,9-11H2
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a 630n/an/an/an/a7.5n/a



Nissan Chemical Industries, Ltd.

US Patent


Assay Description
JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...


US Patent US9216999 (2015)


BindingDB Entry DOI: 10.7270/Q28C9V2J
More data for this
Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2


(Homo sapiens (Human))
BDBM198226
PNG
(US9216999, 34 | US9556187, Example 210)
Show SMILES N#Cc1ccc(CN2CCC(CC2)c2nnn3cnc4[nH]ccc4c23)cc1
Show InChI InChI=1S/C20H19N7/c21-11-14-1-3-15(4-2-14)12-26-9-6-16(7-10-26)18-19-17-5-8-22-20(17)23-13-27(19)25-24-18/h1-5,8,13,16,22H,6-7,9-10,12H2
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a 170n/an/an/an/a7.5n/a



Nissan Chemical Industries, Ltd.

US Patent


Assay Description
JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...


US Patent US9216999 (2015)


BindingDB Entry DOI: 10.7270/Q28C9V2J
More data for this
Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2


(Homo sapiens (Human))
BDBM198227
PNG
(US9216999, 35 | US9556187, Example 35)
Show SMILES N#Cc1cccc(CN2CCC(CC2)c2nnn3cnc4[nH]ccc4c23)c1
Show InChI InChI=1S/C20H19N7/c21-11-14-2-1-3-15(10-14)12-26-8-5-16(6-9-26)18-19-17-4-7-22-20(17)23-13-27(19)25-24-18/h1-4,7,10,13,16,22H,5-6,8-9,12H2
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a 460n/an/an/an/a7.5n/a



Nissan Chemical Industries, Ltd.

US Patent


Assay Description
JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...


US Patent US9216999 (2015)


BindingDB Entry DOI: 10.7270/Q28C9V2J
More data for this
Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2


(Homo sapiens (Human))
BDBM198228
PNG
(US9216999, 36 | US9556187, Example 36)
Show SMILES Cc1noc(C)c1CN1CCC(CC1)c1nnn2cnc3[nH]ccc3c12
Show InChI InChI=1S/C18H21N7O/c1-11-15(12(2)26-22-11)9-24-7-4-13(5-8-24)16-17-14-3-6-19-18(14)20-10-25(17)23-21-16/h3,6,10,13,19H,4-5,7-9H2,1-2H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a>1.00E+3n/an/an/an/a7.5n/a



Nissan Chemical Industries, Ltd.

US Patent


Assay Description
JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...


US Patent US9216999 (2015)


BindingDB Entry DOI: 10.7270/Q28C9V2J
More data for this
Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2


(Homo sapiens (Human))
BDBM198229
PNG
(US9216999, 37 | US9556187, Example 37)
Show SMILES FC(F)(F)Oc1ccc(CN2CCC(CC2)c2nnn3cnc4[nH]ccc4c23)cc1
Show InChI InChI=1S/C20H19F3N6O/c21-20(22,23)30-15-3-1-13(2-4-15)11-28-9-6-14(7-10-28)17-18-16-5-8-24-19(16)25-12-29(18)27-26-17/h1-5,8,12,14,24H,6-7,9-11H2
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a>1.00E+3n/an/an/an/a7.5n/a



Nissan Chemical Industries, Ltd.

US Patent


Assay Description
JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...


US Patent US9216999 (2015)


BindingDB Entry DOI: 10.7270/Q28C9V2J
More data for this
Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2


(Homo sapiens (Human))
BDBM198230
PNG
(US9216999, 38 | US9556187, Example 38)
Show SMILES FC(F)(F)Sc1ccc(CN2CCC(CC2)c2nnn3cnc4[nH]ccc4c23)cc1
Show InChI InChI=1S/C20H19F3N6S/c21-20(22,23)30-15-3-1-13(2-4-15)11-28-9-6-14(7-10-28)17-18-16-5-8-24-19(16)25-12-29(18)27-26-17/h1-5,8,12,14,24H,6-7,9-11H2
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a>1.00E+3n/an/an/an/a7.5n/a



Nissan Chemical Industries, Ltd.

US Patent


Assay Description
JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...


US Patent US9216999 (2015)


BindingDB Entry DOI: 10.7270/Q28C9V2J
More data for this
Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2


(Homo sapiens (Human))
BDBM198231
PNG
(US9216999, 39 | US9556187, Example 39)
Show SMILES FC(F)(F)c1cccc(CN2CCC(CC2)c2nnn3cnc4[nH]ccc4c23)c1
Show InChI InChI=1S/C20H19F3N6/c21-20(22,23)15-3-1-2-13(10-15)11-28-8-5-14(6-9-28)17-18-16-4-7-24-19(16)25-12-29(18)27-26-17/h1-4,7,10,12,14,24H,5-6,8-9,11H2
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a>1.00E+3n/an/an/an/a7.5n/a



Nissan Chemical Industries, Ltd.

US Patent


Assay Description
JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...


US Patent US9216999 (2015)


BindingDB Entry DOI: 10.7270/Q28C9V2J
More data for this
Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2


(Homo sapiens (Human))
BDBM198232
PNG
(US9216999, 40 | US9556187, Example 40)
Show SMILES Fc1cc(ccc1CN1CCC(CC1)c1nnn2cnc3[nH]ccc3c12)C#N
Show InChI InChI=1S/C20H18FN7/c21-17-9-13(10-22)1-2-15(17)11-27-7-4-14(5-8-27)18-19-16-3-6-23-20(16)24-12-28(19)26-25-18/h1-3,6,9,12,14,23H,4-5,7-8,11H2
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a 150n/an/an/an/a7.5n/a



Nissan Chemical Industries, Ltd.

US Patent


Assay Description
JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...


US Patent US9216999 (2015)


BindingDB Entry DOI: 10.7270/Q28C9V2J
More data for this
Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2


(Homo sapiens (Human))
BDBM198233
PNG
(US9216999, 41 | US9556187, Example 41)
Show SMILES Brc1ccc(CN2CCC(CC2)c2nnn3cnc4[nH]ccc4c23)cc1
Show InChI InChI=1S/C19H19BrN6/c20-15-3-1-13(2-4-15)11-25-9-6-14(7-10-25)17-18-16-5-8-21-19(16)22-12-26(18)24-23-17/h1-5,8,12,14,21H,6-7,9-11H2
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a 150n/an/an/an/a7.5n/a



Nissan Chemical Industries, Ltd.

US Patent


Assay Description
JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...


US Patent US9216999 (2015)


BindingDB Entry DOI: 10.7270/Q28C9V2J
More data for this
Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2


(Homo sapiens (Human))
BDBM198234
PNG
(US9216999, 42 | US9556187, Example 42)
Show SMILES FC(F)(F)c1ccc(CCN2CCC(CC2)c2nnn3cnc4[nH]ccc4c23)cc1
Show InChI InChI=1S/C21H21F3N6/c22-21(23,24)16-3-1-14(2-4-16)6-10-29-11-7-15(8-12-29)18-19-17-5-9-25-20(17)26-13-30(19)28-27-18/h1-5,9,13,15,25H,6-8,10-12H2
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a>1.00E+3n/an/an/an/a7.5n/a



Nissan Chemical Industries, Ltd.

US Patent


Assay Description
JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...


US Patent US9216999 (2015)


BindingDB Entry DOI: 10.7270/Q28C9V2J
More data for this
Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2


(Homo sapiens (Human))
BDBM198235
PNG
(US9216999, 43 | US9556187, Example 43)
Show SMILES Fc1ccc(CN2CCC(CC2)c2nnn3cnc4[nH]ccc4c23)cc1
Show InChI InChI=1S/C19H19FN6/c20-15-3-1-13(2-4-15)11-25-9-6-14(7-10-25)17-18-16-5-8-21-19(16)22-12-26(18)24-23-17/h1-5,8,12,14,21H,6-7,9-11H2
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a 100n/an/an/an/a7.5n/a



Nissan Chemical Industries, Ltd.

US Patent


Assay Description
JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...


US Patent US9216999 (2015)


BindingDB Entry DOI: 10.7270/Q28C9V2J
More data for this
Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2


(Homo sapiens (Human))
BDBM198236
PNG
(US9216999, 44 | US9556187, Example 44)
Show SMILES C(N1CCC(CC1)c1nnn2cnc3[nH]ccc3c12)c1cncs1
Show InChI InChI=1S/C16H17N7S/c1-4-18-16-13(1)15-14(20-21-23(15)9-19-16)11-2-5-22(6-3-11)8-12-7-17-10-24-12/h1,4,7,9-11,18H,2-3,5-6,8H2
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a 120n/an/an/an/a7.5n/a



Nissan Chemical Industries, Ltd.

US Patent


Assay Description
JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...


US Patent US9216999 (2015)


BindingDB Entry DOI: 10.7270/Q28C9V2J
More data for this
Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2


(Homo sapiens (Human))
BDBM198237
PNG
(US9216999, 45 | US9556187, Example 45)
Show SMILES C(CN1CCC(CC1)c1nnn2cnc3[nH]ccc3c12)Cc1ccccc1
Show InChI InChI=1S/C21H24N6/c1-2-5-16(6-3-1)7-4-12-26-13-9-17(10-14-26)19-20-18-8-11-22-21(18)23-15-27(20)25-24-19/h1-3,5-6,8,11,15,17,22H,4,7,9-10,12-14H2
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a>1.00E+3n/an/an/an/a7.5n/a



Nissan Chemical Industries, Ltd.

US Patent


Assay Description
JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...


US Patent US9216999 (2015)


BindingDB Entry DOI: 10.7270/Q28C9V2J
More data for this
Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2


(Homo sapiens (Human))
BDBM198238
PNG
(US9216999, 46 | US9556187, Example 46)
Show SMILES COc1ccc(CN2CCC(CC2)c2nnn3cnc4[nH]ccc4c23)cc1F
Show InChI InChI=1S/C20H21FN6O/c1-28-17-3-2-13(10-16(17)21)11-26-8-5-14(6-9-26)18-19-15-4-7-22-20(15)23-12-27(19)25-24-18/h2-4,7,10,12,14,22H,5-6,8-9,11H2,1H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a>1.00E+3n/an/an/an/a7.5n/a



Nissan Chemical Industries, Ltd.

US Patent


Assay Description
JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...


US Patent US9216999 (2015)


BindingDB Entry DOI: 10.7270/Q28C9V2J
More data for this
Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2


(Homo sapiens (Human))
BDBM198239
PNG
(US9216999, 47 | US9556187, Example 47)
Show SMILES FC(F)(F)c1cc(CN2CCC(CC2)c2nnn3cnc4[nH]ccc4c23)cc(c1)C(F)(F)F
Show InChI InChI=1S/C21H18F6N6/c22-20(23,24)14-7-12(8-15(9-14)21(25,26)27)10-32-5-2-13(3-6-32)17-18-16-1-4-28-19(16)29-11-33(18)31-30-17/h1,4,7-9,11,13,28H,2-3,5-6,10H2
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a>1.00E+3n/an/an/an/a7.5n/a



Nissan Chemical Industries, Ltd.

US Patent


Assay Description
JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...


US Patent US9216999 (2015)


BindingDB Entry DOI: 10.7270/Q28C9V2J
More data for this
Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2


(Homo sapiens (Human))
BDBM198240
PNG
(US9216999, 48 | US9556187, Example 48)
Show SMILES C(N1CCC(CC1)c1nnn2cnc3[nH]ccc3c12)c1nccs1
Show InChI InChI=1S/C16H17N7S/c1-4-18-16-12(1)15-14(20-21-23(15)10-19-16)11-2-6-22(7-3-11)9-13-17-5-8-24-13/h1,4-5,8,10-11,18H,2-3,6-7,9H2
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a 460n/an/an/an/a7.5n/a



Nissan Chemical Industries, Ltd.

US Patent


Assay Description
JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...


US Patent US9216999 (2015)


BindingDB Entry DOI: 10.7270/Q28C9V2J
More data for this
Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2


(Homo sapiens (Human))
BDBM198241
PNG
(US9216999, 49 | US9556187, Example 49)
Show SMILES Clc1ccc(CN2CCC(CC2)c2nnn3cnc4[nH]ccc4c23)s1
Show InChI InChI=1S/C17H17ClN6S/c18-14-2-1-12(25-14)9-23-7-4-11(5-8-23)15-16-13-3-6-19-17(13)20-10-24(16)22-21-15/h1-3,6,10-11,19H,4-5,7-9H2
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a 57n/an/an/an/a7.5n/a



Nissan Chemical Industries, Ltd.

US Patent


Assay Description
JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...


US Patent US9216999 (2015)


BindingDB Entry DOI: 10.7270/Q28C9V2J
More data for this
Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2


(Homo sapiens (Human))
BDBM198242
PNG
(US9216999, 50 | US9556187, Example 50)
Show SMILES C(C1CCCCC1)N1CCC(CC1)c1nnn2cnc3[nH]ccc3c12
Show InChI InChI=1S/C19H26N6/c1-2-4-14(5-3-1)12-24-10-7-15(8-11-24)17-18-16-6-9-20-19(16)21-13-25(18)23-22-17/h6,9,13-15,20H,1-5,7-8,10-12H2
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a>1.00E+3n/an/an/an/a7.5n/a



Nissan Chemical Industries, Ltd.

US Patent


Assay Description
JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...


US Patent US9216999 (2015)


BindingDB Entry DOI: 10.7270/Q28C9V2J
More data for this
Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2


(Homo sapiens (Human))
BDBM198243
PNG
(US9216999, 51 | US9556187, Example 51)
Show SMILES C1CCC(C1)N1CCC(CC1)c1nnn2cnc3[nH]ccc3c12
Show InChI InChI=1S/C17H22N6/c1-2-4-13(3-1)22-9-6-12(7-10-22)15-16-14-5-8-18-17(14)19-11-23(16)21-20-15/h5,8,11-13,18H,1-4,6-7,9-10H2
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a>1.00E+3n/an/an/an/a7.5n/a



Nissan Chemical Industries, Ltd.

US Patent


Assay Description
JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...


US Patent US9216999 (2015)


BindingDB Entry DOI: 10.7270/Q28C9V2J
More data for this
Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2


(Homo sapiens (Human))
BDBM198244
PNG
(US9216999, 52 | US9556187, Example 52)
Show SMILES FC(F)(F)c1ccc(CN2CCC(CC2)c2nnn3cnc4[nH]ccc4c23)cn1
Show InChI InChI=1S/C19H18F3N7/c20-19(21,22)15-2-1-12(9-24-15)10-28-7-4-13(5-8-28)16-17-14-3-6-23-18(14)25-11-29(17)27-26-16/h1-3,6,9,11,13,23H,4-5,7-8,10H2
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a 360n/an/an/an/a7.5n/a



Nissan Chemical Industries, Ltd.

US Patent


Assay Description
JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...


US Patent US9216999 (2015)


BindingDB Entry DOI: 10.7270/Q28C9V2J
More data for this
Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2


(Homo sapiens (Human))
BDBM198245
PNG
(US9216999, 53 | US9556187, Example 53)
Show SMILES Fc1cc(cc(F)c1CN1CCC(CC1)c1nnn2cnc3[nH]ccc3c12)C#N
Show InChI InChI=1S/C20H17F2N7/c21-16-7-12(9-23)8-17(22)15(16)10-28-5-2-13(3-6-28)18-19-14-1-4-24-20(14)25-11-29(19)27-26-18/h1,4,7-8,11,13,24H,2-3,5-6,10H2
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a 47n/an/an/an/a7.5n/a



Nissan Chemical Industries, Ltd.

US Patent


Assay Description
JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...


US Patent US9216999 (2015)


BindingDB Entry DOI: 10.7270/Q28C9V2J
More data for this
Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2


(Homo sapiens (Human))
BDBM198246
PNG
(US9216999, 54 | US9556187, Example 54)
Show SMILES Clc1ccc(CN2CCC(CC2)c2nnn3cnc4[nH]ccc4c23)cc1
Show InChI InChI=1S/C19H19ClN6/c20-15-3-1-13(2-4-15)11-25-9-6-14(7-10-25)17-18-16-5-8-21-19(16)22-12-26(18)24-23-17/h1-5,8,12,14,21H,6-7,9-11H2
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a 210n/an/an/an/a7.5n/a



Nissan Chemical Industries, Ltd.

US Patent


Assay Description
JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...


US Patent US9216999 (2015)


BindingDB Entry DOI: 10.7270/Q28C9V2J
More data for this
Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2


(Homo sapiens (Human))
BDBM198247
PNG
(US9216999, 55 | US9556187, Example 55)
Show SMILES Fc1cccc(CN2CCC(CC2)c2nnn3cnc4[nH]ccc4c23)c1
Show InChI InChI=1S/C19H19FN6/c20-15-3-1-2-13(10-15)11-25-8-5-14(6-9-25)17-18-16-4-7-21-19(16)22-12-26(18)24-23-17/h1-4,7,10,12,14,21H,5-6,8-9,11H2
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a 390n/an/an/an/a7.5n/a



Nissan Chemical Industries, Ltd.

US Patent


Assay Description
JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...


US Patent US9216999 (2015)


BindingDB Entry DOI: 10.7270/Q28C9V2J
More data for this
Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2


(Homo sapiens (Human))
BDBM198248
PNG
(US9216999, 56a | US9556187, Example 56b)
Show SMILES FC(F)(F)C1CCC(CC1)N1CCC(CC1)c1nnn2cnc3[nH]ccc3c12
Show InChI InChI=1S/C19H23F3N6/c20-19(21,22)13-1-3-14(4-2-13)27-9-6-12(7-10-27)16-17-15-5-8-23-18(15)24-11-28(17)26-25-16/h5,8,11-14,23H,1-4,6-7,9-10H2
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a>1.00E+3n/an/an/an/a7.5n/a



Nissan Chemical Industries, Ltd.

US Patent


Assay Description
JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...


US Patent US9216999 (2015)


BindingDB Entry DOI: 10.7270/Q28C9V2J
More data for this
Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2


(Homo sapiens (Human))
BDBM198249
PNG
(US9216999, 56b)
Show SMILES FC(F)(F)C1CCC(CC1)N1CCC(CC1)c1nnn2cnc3[nH]ccc3c12
Show InChI InChI=1S/C19H23F3N6/c20-19(21,22)13-1-3-14(4-2-13)27-9-6-12(7-10-27)16-17-15-5-8-23-18(15)24-11-28(17)26-25-16/h5,8,11-14,23H,1-4,6-7,9-10H2
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a>1.00E+3n/an/an/an/a7.5n/a



Nissan Chemical Industries, Ltd.

US Patent


Assay Description
JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...


US Patent US9216999 (2015)


BindingDB Entry DOI: 10.7270/Q28C9V2J
More data for this
Ligand-Target Pair
Displayed 1 to 50 (of 463 total )  |  Next  |  Last  >>
Jump to: