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Found 12 of ph data with Target = 'Nuclear receptor subfamily 1 group I member 2'
TargetNuclear receptor subfamily 1 group I member 2(Homo sapiens (Human))
University Of North Carolina At Chapel Hill

LigandPNGBDBM19993(CHEMBL62136 | N-[4-(1,1,1,3,3,3-hexafluoro-2-hydro...)
Affinity DataIC50:  40nM EC50:  13nMpH: 8.0 T: 2°CAssay Description:Polylysine YiO imaging beads (Amersham, GE Healthcare) were coated with histidine-tagged WT PXR LBD. Nonspecific binding sites were blocked with BSA....More data for this Ligand-Target Pair
TargetNuclear receptor subfamily 1 group I member 2(Homo sapiens (Human))
University Of North Carolina At Chapel Hill

LigandPNGBDBM21663(N-[4-(2,2,2-trifluoro-1-hydroxyethyl)phenyl]-N-(2,...)
Affinity DataIC50:  1.00E+4nM EC50:  1.00E+3nMpH: 8.0 T: 2°CAssay Description:Polylysine YiO imaging beads (Amersham, GE Healthcare) were coated with histidine-tagged WT PXR LBD. Nonspecific binding sites were blocked with BSA....More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNuclear receptor subfamily 1 group I member 2(Homo sapiens (Human))
University Of North Carolina At Chapel Hill

LigandPNGBDBM21664(N-[4-(1,1,1-trifluoro-2-hydroxypropan-2-yl)phenyl]...)
Affinity DataIC50:  3.98E+3nM EC50:  501nMpH: 8.0 T: 2°CAssay Description:Polylysine YiO imaging beads (Amersham, GE Healthcare) were coated with histidine-tagged WT PXR LBD. Nonspecific binding sites were blocked with BSA....More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNuclear receptor subfamily 1 group I member 2(Homo sapiens (Human))
University Of North Carolina At Chapel Hill

LigandPNGBDBM21665(N-[4-(1,1,1-trifluoro-2-hydroxybutan-2-yl)phenyl]-...)
Affinity DataIC50:  251nM EC50:  126nMpH: 8.0 T: 2°CAssay Description:Polylysine YiO imaging beads (Amersham, GE Healthcare) were coated with histidine-tagged WT PXR LBD. Nonspecific binding sites were blocked with BSA....More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNuclear receptor subfamily 1 group I member 2(Homo sapiens (Human))
University Of North Carolina At Chapel Hill

LigandPNGBDBM21666(N-[4-(1,1,1-trifluoro-2-hydroxypentan-2-yl)phenyl]...)
Affinity DataIC50:  316nM EC50:  158nMpH: 8.0 T: 2°CAssay Description:Polylysine YiO imaging beads (Amersham, GE Healthcare) were coated with histidine-tagged WT PXR LBD. Nonspecific binding sites were blocked with BSA....More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNuclear receptor subfamily 1 group I member 2(Homo sapiens (Human))
University Of North Carolina At Chapel Hill

LigandPNGBDBM21673(N-[4-(1,1,1,3,3,4,4,5,5,5-decafluoro-2-hydroxypent...)
Affinity DataIC50:  20nM EC50:  10nMpH: 8.0 T: 2°CAssay Description:Polylysine YiO imaging beads (Amersham, GE Healthcare) were coated with histidine-tagged WT PXR LBD. Nonspecific binding sites were blocked with BSA....More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNuclear receptor subfamily 1 group I member 2(Homo sapiens (Human))
University Of North Carolina At Chapel Hill

LigandPNGBDBM21668(N-[4-(1-hydroxyethyl)phenyl]-N-(2,2,2-trifluoroeth...)
Affinity DataIC50:  2.51E+3nM EC50:  1.00E+4nMpH: 8.0 T: 2°CAssay Description:Polylysine YiO imaging beads (Amersham, GE Healthcare) were coated with histidine-tagged WT PXR LBD. Nonspecific binding sites were blocked with BSA....More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNuclear receptor subfamily 1 group I member 2(Homo sapiens (Human))
University Of North Carolina At Chapel Hill

LigandPNGBDBM21669(N-(4-acetylphenyl)-N-(2,2,2-trifluoroethyl)benzene...)
Affinity DataIC50:  1.59E+3nM EC50:  1.00E+4nMpH: 8.0 T: 2°CAssay Description:Polylysine YiO imaging beads (Amersham, GE Healthcare) were coated with histidine-tagged WT PXR LBD. Nonspecific binding sites were blocked with BSA....More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNuclear receptor subfamily 1 group I member 2(Homo sapiens (Human))
University Of North Carolina At Chapel Hill

LigandPNGBDBM21670(N-[4-(1-cyclohexyl-2,2,2-trifluoro-1-hydroxyethyl)...)
Affinity DataIC50:  25nM EC50:  3nMpH: 8.0 T: 2°CAssay Description:Polylysine YiO imaging beads (Amersham, GE Healthcare) were coated with histidine-tagged WT PXR LBD. Nonspecific binding sites were blocked with BSA....More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNuclear receptor subfamily 1 group I member 2(Homo sapiens (Human))
University Of North Carolina At Chapel Hill

LigandPNGBDBM21671(N-[4-(2,2,2-trifluoro-1-hydroxy-1-phenylethyl)phen...)
Affinity DataIC50:  63nM EC50:  16nMpH: 8.0 T: 2°CAssay Description:Polylysine YiO imaging beads (Amersham, GE Healthcare) were coated with histidine-tagged WT PXR LBD. Nonspecific binding sites were blocked with BSA....More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNuclear receptor subfamily 1 group I member 2(Homo sapiens (Human))
University Of North Carolina At Chapel Hill

LigandPNGBDBM21672(N-[4-(1,1,1-trifluoro-2-hydroxy-4-phenylbut-3-yn-2...)
Affinity DataIC50:  631nM EC50:  1.00E+3nMpH: 8.0 T: 2°CAssay Description:Polylysine YiO imaging beads (Amersham, GE Healthcare) were coated with histidine-tagged WT PXR LBD. Nonspecific binding sites were blocked with BSA....More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNuclear receptor subfamily 1 group I member 2(Homo sapiens (Human))
University Of North Carolina At Chapel Hill

LigandPNGBDBM21667(N-[4-(hydroxymethyl)phenyl]-N-(2,2,2-trifluoroethy...)
Affinity DataIC50:  7.94E+3nM EC50:  1.00E+4nMpH: 8.0 T: 2°CAssay Description:Polylysine YiO imaging beads (Amersham, GE Healthcare) were coated with histidine-tagged WT PXR LBD. Nonspecific binding sites were blocked with BSA....More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed