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Compile Data Set for Download or QSAR

Found 9 hits of ph data with Target = 'Oligosaccharyl transferase (OT)'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Oligosaccharyl transferase (OT)


(Saccharomyces cerevisiae (Baker's yeast))
BDBM43866
PNG
(2-amino-4,6-dimethyl-3-oxo-1-N,9-N-bis[(3R,6S,7R,1...)
Show SMILES CC(C)[C@H]1NC(=O)[C@@H](NC(=O)c2ccc(C)c3oc4c(C)c(=O)c(N)c(C(=O)N[C@H]5[C@@H](C)OC(=O)[C@H](C(C)C)N(C)C(=O)CN(C)C(=O)[C@@H]6CCCN6C(=O)[C@H](NC5=O)C(C)C)c4nc23)[C@@H](C)OC(=O)[C@H](C(C)C)N(C)C(=O)CN(C)C(=O)[C@@H]2CCCN2C1=O
Show InChI InChI=1S/C62H86N12O16/c1-27(2)42-59(84)73-23-17-19-36(73)57(82)69(13)25-38(75)71(15)48(29(5)6)61(86)88-33(11)44(55(80)65-42)67-53(78)35-22-21-31(9)51-46(35)64-47-40(41(63)50(77)32(10)52(47)90-51)54(79)68-45-34(12)89-62(87)49(30(7)8)72(16)39(76)26-70(14)58(83)37-20-18-24-74(37)60(85)43(28(3)4)66-56(45)81/h21-22,27-30,33-34,36-37,42-45,48-49H,17-20,23-26,63H2,1-16H3,(H,65,80)(H,66,81)(H,67,78)(H,68,79)/t33-,34-,36+,37+,42-,43-,44+,45+,48+,49+/m1/s1
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PubMed
41 -38.6n/an/an/an/an/a7.50



Massachusetts Institute of Technology



Assay Description
Competition assay using S. cerevisiae oligosaccharyl transferase (OT)with disaccharide donor Dol-P-P-(GlcNAc)2 and the tripeptide substrate Bz-Asn-Le...


Chem Biol 9: 1323-8 (2002)


Article DOI: 10.1016/S1074-5521(02)00281-8
BindingDB Entry DOI: 10.7270/Q2736P9D
More data for this
Ligand-Target Pair
Oligosaccharyl transferase (OT)


(Saccharomyces cerevisiae (Baker's yeast))
BDBM43865
PNG
(6-formyl-4,7-dihydroxy-9-keto-5H-phenazine-1-carbo...)
Show SMILES COC(=O)c1ccc(O)c2nc3c(C=O)c(O)cc(O)c3nc12
Show InChI InChI=1S/C15H10N2O6/c1-23-15(22)6-2-3-8(19)13-11(6)16-14-10(21)4-9(20)7(5-18)12(14)17-13/h2-5,19-21H,1H3
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62 -37.7n/an/an/an/an/a7.50



Massachusetts Institute of Technology



Assay Description
Competition assay using S. cerevisiae oligosaccharyl transferase (OT)with disaccharide donor Dol-P-P-(GlcNAc)2 and the tripeptide substrate Bz-Asn-Le...


Chem Biol 9: 1323-8 (2002)


Article DOI: 10.1016/S1074-5521(02)00281-8
BindingDB Entry DOI: 10.7270/Q2736P9D
More data for this
Ligand-Target Pair
Oligosaccharyl transferase (OT)


(Saccharomyces cerevisiae (Baker's yeast))
BDBM43863
PNG
(3-[[4-amino-6-(2,5-dimethoxyanilino)-5-nitro-pyrim...)
Show SMILES COc1ccc(OC)c(Nc2nc(NCCCN(C)C)nc(N)c2[N+]([O-])=O)c1
Show InChI InChI=1S/C17H25N7O4/c1-23(2)9-5-8-19-17-21-15(18)14(24(25)26)16(22-17)20-12-10-11(27-3)6-7-13(12)28-4/h6-7,10H,5,8-9H2,1-4H3,(H4,18,19,20,21,22)
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PubMed
1.10E+3 -31.2n/an/an/an/an/a7.50



Massachusetts Institute of Technology



Assay Description
Competition assay using S. cerevisiae oligosaccharyl transferase (OT)with disaccharide donor Dol-P-P-(GlcNAc)2 and the tripeptide substrate Bz-Asn-Le...


Chem Biol 9: 1323-8 (2002)


Article DOI: 10.1016/S1074-5521(02)00281-8
BindingDB Entry DOI: 10.7270/Q2736P9D
More data for this
Ligand-Target Pair
Oligosaccharyl transferase (OT)


(Saccharomyces cerevisiae (Baker's yeast))
BDBM43860
PNG
(Glycopeptide, 2 | MLS000517385 | N-(4-acetamidophe...)
Show SMILES CC(=O)Nc1ccc(NC(=O)c2ccc(Cl)nc2)cc1
Show InChI InChI=1S/C14H12ClN3O2/c1-9(19)17-11-3-5-12(6-4-11)18-14(20)10-2-7-13(15)16-8-10/h2-8H,1H3,(H,17,19)(H,18,20)
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PubMed
2.50E+3 -29.3n/an/an/an/an/a7.50



Massachusetts Institute of Technology



Assay Description
Competition assay using S. cerevisiae oligosaccharyl transferase (OT)with disaccharide donor Dol-P-P-(GlcNAc)2 and the tripeptide substrate Bz-Asn-Le...


Chem Biol 9: 1323-8 (2002)


Article DOI: 10.1016/S1074-5521(02)00281-8
BindingDB Entry DOI: 10.7270/Q2736P9D
More data for this
Ligand-Target Pair
Oligosaccharyl transferase (OT)


(Saccharomyces cerevisiae (Baker's yeast))
BDBM43864
PNG
(2-chloranyl-N1,N4-bis[4-(4,5-dihydro-1H-imidazol-2...)
Show SMILES Clc1cc(ccc1C(=O)Nc1ccc(cc1)C1=NCCN1)C(=O)Nc1ccc(cc1)C1=NCCN1
Show InChI InChI=1S/C26H23ClN6O2/c27-22-15-18(25(34)32-19-6-1-16(2-7-19)23-28-11-12-29-23)5-10-21(22)26(35)33-20-8-3-17(4-9-20)24-30-13-14-31-24/h1-10,15H,11-14H2,(H,28,29)(H,30,31)(H,32,34)(H,33,35)
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PubMed
4.00E+3 -28.2n/an/an/an/an/a7.50



Massachusetts Institute of Technology



Assay Description
Competition assay using S. cerevisiae oligosaccharyl transferase (OT)with disaccharide donor Dol-P-P-(GlcNAc)2 and the tripeptide substrate Bz-Asn-Le...


Chem Biol 9: 1323-8 (2002)


Article DOI: 10.1016/S1074-5521(02)00281-8
BindingDB Entry DOI: 10.7270/Q2736P9D
More data for this
Ligand-Target Pair
Oligosaccharyl transferase (OT)


(Saccharomyces cerevisiae (Baker's yeast))
BDBM43861
PNG
(4-[7-[4-[diethyl(methyl)ammonio]butoxy]-9-keto-flu...)
Show SMILES CC[N+](C)(CC)CCCCOc1ccc2-c3ccc(OCCCC[N+](C)(CC)CC)cc3C(=O)c2c1
Show InChI InChI=1S/C31H48N2O3/c1-7-32(5,8-2)19-11-13-21-35-25-15-17-27-28-18-16-26(24-30(28)31(34)29(27)23-25)36-22-14-12-20-33(6,9-3)10-4/h15-18,23-24H,7-14,19-22H2,1-6H3/q+2
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4.50E+3 -28.0n/an/an/an/an/a7.50



Massachusetts Institute of Technology



Assay Description
Competition assay using S. cerevisiae oligosaccharyl transferase (OT)with disaccharide donor Dol-P-P-(GlcNAc)2 and the tripeptide substrate Bz-Asn-Le...


Chem Biol 9: 1323-8 (2002)


Article DOI: 10.1016/S1074-5521(02)00281-8
BindingDB Entry DOI: 10.7270/Q2736P9D
More data for this
Ligand-Target Pair
Oligosaccharyl transferase (OT)


(Saccharomyces cerevisiae (Baker's yeast))
BDBM43862
PNG
(2-(aminocarbonylamino)-N-[4-[(4-methoxyphenyl)sulf...)
Show SMILES COc1ccc(NS(=O)(=O)c2ccc(NC(=O)C(CCSC)NC(N)=O)cc2)cc1
Show InChI InChI=1S/C19H24N4O5S2/c1-28-15-7-3-14(4-8-15)23-30(26,27)16-9-5-13(6-10-16)21-18(24)17(11-12-29-2)22-19(20)25/h3-10,17,23H,11-12H2,1-2H3,(H,21,24)(H3,20,22,25)
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PubMed
3.40E+4 -23.4n/an/an/an/an/a7.50



Massachusetts Institute of Technology



Assay Description
Competition assay using S. cerevisiae oligosaccharyl transferase (OT)with disaccharide donor Dol-P-P-(GlcNAc)2 and the tripeptide substrate Bz-Asn-Le...


Chem Biol 9: 1323-8 (2002)


Article DOI: 10.1016/S1074-5521(02)00281-8
BindingDB Entry DOI: 10.7270/Q2736P9D
More data for this
Ligand-Target Pair
Oligosaccharyl transferase (OT)


(Saccharomyces cerevisiae (Baker's yeast))
BDBM43859
PNG
(2-[[4-(4-methoxyphenyl)-1,2,4-triazol-3-yl]sulfany...)
Show SMILES COc1ccc(cc1)-n1cnnc1SCC(=O)Nc1cc(C)on1
Show InChI InChI=1S/C15H15N5O3S/c1-10-7-13(19-23-10)17-14(21)8-24-15-18-16-9-20(15)11-3-5-12(22-2)6-4-11/h3-7,9H,8H2,1-2H3,(H,17,19,21)
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PubMed
1.00E+5 -20.9n/an/an/an/an/a7.50



Massachusetts Institute of Technology



Assay Description
Competition assay using S. cerevisiae oligosaccharyl transferase (OT)with disaccharide donor Dol-P-P-(GlcNAc)2 and the tripeptide substrate Bz-Asn-Le...


Chem Biol 9: 1323-8 (2002)


Article DOI: 10.1016/S1074-5521(02)00281-8
BindingDB Entry DOI: 10.7270/Q2736P9D
More data for this
Ligand-Target Pair
Oligosaccharyl transferase (OT)


(Saccharomyces cerevisiae (Baker's yeast))
BDBM43867
PNG
(Glycopeptide, 1)
Show SMILES CC(C)C(NC(=O)C(NC(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(=O)c1ccccc1)[C@H](C)O)C(=O)NC([C@H](C)O)C(=O)N[C@@H](Cc1ccc(cc1)N(=O)=O)C(N)=O
Show InChI InChI=1S/C37H51N9O12/c1-18(2)28(35(54)45-29(20(4)47)36(55)42-26(31(39)50)17-22-11-13-24(14-12-22)46(57)58)43-37(56)30(21(5)48)44-32(51)19(3)40-34(53)25(15-16-27(38)49)41-33(52)23-9-7-6-8-10-23/h6-14,18-21,25-26,28-30,47-48H,15-17H2,1-5H3,(H2,38,49)(H2,39,50)(H,40,53)(H,41,52)(H,42,55)(H,43,56)(H,44,51)(H,45,54)/t19-,20-,21-,25-,26-,28?,29?,30?/m0/s1
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n/an/an/an/an/an/an/a7.50



Massachusetts Institute of Technology



Assay Description
Competition assay using S. cerevisiae oligosaccharyl transferase (OT)with disaccharide donor Dol-P-P-(GlcNAc)2 and the tripeptide substrate Bz-Asn-Le...


Chem Biol 9: 1323-8 (2002)


Article DOI: 10.1016/S1074-5521(02)00281-8
BindingDB Entry DOI: 10.7270/Q2736P9D
More data for this
Ligand-Target Pair