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Compile Data Set for Download or QSAR

Found 1 hit of ph data with Target = 'Phosphoinositide 3-Kinase (PI3K), beta'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Phosphoinositide 3-Kinase (PI3K), beta


(Homo sapiens (human))
BDBM21036
PNG
((2R,3S,6Z,14S,15S,17R)-6-({[3-(dimethylamino)propy...)
Show SMILES COC[C@H]1OC(=O)C(=CN(C)CCCN(C)C)C2C(=O)C(=O)C3=C([C@@H](C[C@]4(C)[C@@H](O)CCC34)OC(C)=O)[C@@]12C
Show InChI InChI=1S/C29H42N2O8/c1-16(32)38-19-13-28(2)18(9-10-20(28)33)22-24(19)29(3)21(15-37-7)39-27(36)17(23(29)26(35)25(22)34)14-31(6)12-8-11-30(4)5/h14,18-21,23,33H,8-13,15H2,1-7H3/t18?,19-,20+,21-,23?,28+,29+/m1/s1
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 13n/an/an/an/a7.522



Wyeth Research



Assay Description
Inhibition of PI3K enzyme activity is measured in a microtiter plate-based fluorescence polarization (FP) assay.


J Med Chem 51: 1319-23 (2008)


Article DOI: 10.1021/jm7012858
BindingDB Entry DOI: 10.7270/Q2NP22QD
More data for this
Ligand-Target Pair