Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Prostaglandin G/H synthase (Cyclooxygenase-2) (Ovis aries (Sheep)) | BDBM235660![]() (3-(5-Phenyl-[1,3,4]oxadiazol-2-yl)-chromen-2-one (...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 8.70E+3 | n/a | n/a | n/a | n/a | 8.0 | 37 |
Jamia Hamdard University | Assay Description Selected 1,3,4-oxadiazole derivatives (4a, 4b, 4c, 4e, 6b, 6e, 8b) were tested for their ability to inhibit COX-1 and COX-2 using a COX-(ovine) inhib... | J Enzyme Inhib Med Chem 26: 767-76 (2011) Article DOI: 10.3109/14756366.2010.550890 BindingDB Entry DOI: 10.7270/Q21J98NP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase (Cyclooxygenase-2) (Ovis aries (Sheep)) | BDBM11639![]() (4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | 3.05E+4 | n/a | n/a | n/a | n/a | 8.0 | 37 |
Jamia Hamdard University | Assay Description Selected 1,3,4-oxadiazole derivatives (4a, 4b, 4c, 4e, 6b, 6e, 8b) were tested for their ability to inhibit COX-1 and COX-2 using a COX-(ovine) inhib... | J Enzyme Inhib Med Chem 26: 767-76 (2011) Article DOI: 10.3109/14756366.2010.550890 BindingDB Entry DOI: 10.7270/Q21J98NP | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
Prostaglandin G/H synthase (Cyclooxygenase-2) (Ovis aries (Sheep)) | BDBM235661![]() (3-[5-(4-Chloro-phenyl)-[1,3,4]oxadiazol-2-yl]-chro...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.20E+3 | n/a | n/a | n/a | n/a | 8.0 | 37 |
Jamia Hamdard University | Assay Description Selected 1,3,4-oxadiazole derivatives (4a, 4b, 4c, 4e, 6b, 6e, 8b) were tested for their ability to inhibit COX-1 and COX-2 using a COX-(ovine) inhib... | J Enzyme Inhib Med Chem 26: 767-76 (2011) Article DOI: 10.3109/14756366.2010.550890 BindingDB Entry DOI: 10.7270/Q21J98NP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase (Cyclooxygenase-2) (Ovis aries (Sheep)) | BDBM235662![]() (3-(5-p-Tolyl-[1,3,4]oxadiazol-2-yl)-chromen-2-one ...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.18E+3 | n/a | n/a | n/a | n/a | 8.0 | 37 |
Jamia Hamdard University | Assay Description Selected 1,3,4-oxadiazole derivatives (4a, 4b, 4c, 4e, 6b, 6e, 8b) were tested for their ability to inhibit COX-1 and COX-2 using a COX-(ovine) inhib... | J Enzyme Inhib Med Chem 26: 767-76 (2011) Article DOI: 10.3109/14756366.2010.550890 BindingDB Entry DOI: 10.7270/Q21J98NP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase (Cyclooxygenase-2) (Ovis aries (Sheep)) | BDBM11639![]() (4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | 90 | n/a | n/a | n/a | n/a | 8.0 | 37 |
Jamia Hamdard University | Assay Description Selected 1,3,4-oxadiazole derivatives (4a, 4b, 4c, 4e, 6b, 6e, 8b) were tested for their ability to inhibit COX-1 and COX-2 using a COX-(ovine) inhib... | J Enzyme Inhib Med Chem 26: 767-76 (2011) Article DOI: 10.3109/14756366.2010.550890 BindingDB Entry DOI: 10.7270/Q21J98NP | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
Prostaglandin G/H synthase (Cyclooxygenase-2) (Ovis aries (Sheep)) | BDBM235664![]() (3-[5-(4-Chloro-phenylamino)-[1,3,4]oxadiazol-2-yl]...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | 8.0 | 37 |
Jamia Hamdard University | Assay Description Selected 1,3,4-oxadiazole derivatives (4a, 4b, 4c, 4e, 6b, 6e, 8b) were tested for their ability to inhibit COX-1 and COX-2 using a COX-(ovine) inhib... | J Enzyme Inhib Med Chem 26: 767-76 (2011) Article DOI: 10.3109/14756366.2010.550890 BindingDB Entry DOI: 10.7270/Q21J98NP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase (Cyclooxygenase-2) (Ovis aries (Sheep)) | BDBM235665![]() (3-(5-o-Tolylamino-[1,3,4]oxadiazol-2-yl)-chromen-2...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 3.66E+4 | n/a | n/a | n/a | n/a | 8.0 | 37 |
Jamia Hamdard University | Assay Description Selected 1,3,4-oxadiazole derivatives (4a, 4b, 4c, 4e, 6b, 6e, 8b) were tested for their ability to inhibit COX-1 and COX-2 using a COX-(ovine) inhib... | J Enzyme Inhib Med Chem 26: 767-76 (2011) Article DOI: 10.3109/14756366.2010.550890 BindingDB Entry DOI: 10.7270/Q21J98NP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase (Cyclooxygenase-2) (Ovis aries (Sheep)) | BDBM235666![]() (4-Chloro-N-[5-(2-oxo-2H-chromen-3-yl)-[1,3,4]oxadi...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | 8.0 | 37 |
Jamia Hamdard University | Assay Description Selected 1,3,4-oxadiazole derivatives (4a, 4b, 4c, 4e, 6b, 6e, 8b) were tested for their ability to inhibit COX-1 and COX-2 using a COX-(ovine) inhib... | J Enzyme Inhib Med Chem 26: 767-76 (2011) Article DOI: 10.3109/14756366.2010.550890 BindingDB Entry DOI: 10.7270/Q21J98NP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase (Cyclooxygenase-2) (Ovis aries (Sheep)) | BDBM235663![]() (3-[5-(2,4-Dichloro-phenyl)-[1,3,4]oxadiazol-2-yl]-...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 400 | n/a | n/a | n/a | n/a | 8.0 | 37 |
Jamia Hamdard University | Assay Description Selected 1,3,4-oxadiazole derivatives (4a, 4b, 4c, 4e, 6b, 6e, 8b) were tested for their ability to inhibit COX-1 and COX-2 using a COX-(ovine) inhib... | J Enzyme Inhib Med Chem 26: 767-76 (2011) Article DOI: 10.3109/14756366.2010.550890 BindingDB Entry DOI: 10.7270/Q21J98NP | |||||||||||
More data for this Ligand-Target Pair |