Found 113 of ph data with Target = 'Prostaglandin G/H synthase 2' 
Affinity DataIC50: 170nMpH: 8.0 T: 2°CAssay Description:For the time-dependent inhibition studies, COX enzyme was incubated with test co mpounds for 20 min and then analyzed for remaining COX activity by t...More data for this Ligand-Target Pair
Affinity DataIC50: 270nMpH: 8.0 T: 2°CAssay Description:For the time-dependent inhibition studies, COX enzyme was incubated with test co mpounds for 20 min and then analyzed for remaining COX activity by t...More data for this Ligand-Target Pair
Affinity DataIC50: 100nMpH: 8.0 T: 2°CAssay Description:For the time-dependent inhibition studies, COX enzyme was incubated with test co mpounds for 20 min and then analyzed for remaining COX activity by t...More data for this Ligand-Target Pair
Affinity DataIC50: 280nMpH: 8.0 T: 2°CAssay Description:For the time-dependent inhibition studies, COX enzyme was incubated with test co mpounds for 20 min and then analyzed for remaining COX activity by t...More data for this Ligand-Target Pair
Affinity DataIC50: 250nMpH: 8.0 T: 2°CAssay Description:For the time-dependent inhibition studies, COX enzyme was incubated with test co mpounds for 20 min and then analyzed for remaining COX activity by t...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMpH: 8.0 T: 2°CAssay Description:For the time-dependent inhibition studies, COX enzyme was incubated with test co mpounds for 20 min and then analyzed for remaining COX activity by t...More data for this Ligand-Target Pair
Affinity DataIC50: 440nMpH: 8.0 T: 2°CAssay Description:For the time-dependent inhibition studies, COX enzyme was incubated with test co mpounds for 20 min and then analyzed for remaining COX activity by t...More data for this Ligand-Target Pair
Affinity DataIC50: 85nMpH: 8.0 T: 2°CAssay Description:For the time-dependent inhibition studies, COX enzyme was incubated with test co mpounds for 20 min and then analyzed for remaining COX activity by t...More data for this Ligand-Target Pair
Affinity DataIC50: 2.62E+5nMpH: 8.0 T: 2°CAssay Description:The COX enzyme activities were measured using the COX Inhibitor Screening Assay kit provided by Cayman (Cayman, Chemical Co., Ann Arbor, MI). The ass...More data for this Ligand-Target Pair
Affinity DataIC50: 2.40E+3nMpH: 8.0 T: 2°CAssay Description:The COX enzyme activities were measured using the COX Inhibitor Screening Assay kit provided by Cayman (Cayman, Chemical Co., Ann Arbor, MI). The as...More data for this Ligand-Target Pair
Affinity DataIC50: 500nMpH: 8.0 T: 2°CAssay Description:The COX enzyme activities were measured using the COX Inhibitor Screening Assay kit provided by Cayman (Cayman, Chemical Co., Ann Arbor, MI). The as...More data for this Ligand-Target Pair
3D Structure (crystal)
Affinity DataIC50: 70nMpH: 8.0 T: 2°CAssay Description:The COX enzyme activities were measured using the COX Inhibitor Screening Assay kit provided by Cayman (Cayman, Chemical Co., Ann Arbor, MI). The as...More data for this Ligand-Target Pair
Affinity DataIC50: 4.66E+4nMpH: 8.0 T: 2°CAssay Description:Reaction mixture containing 100 mM Tris-HCl buffer (pH 8) and COX-1 (ovine) or COX-2 (human recombinant) was preincubated for 10 min in a water bath ...More data for this Ligand-Target Pair
Affinity DataIC50: 5.32E+4nMpH: 8.0 T: 2°CAssay Description:Reaction mixture containing 100 mM Tris-HCl buffer (pH 8) and COX-1 (ovine) or COX-2 (human recombinant) was preincubated for 10 min in a water bath ...More data for this Ligand-Target Pair
Affinity DataIC50: 5.78E+4nMpH: 8.0 T: 2°CAssay Description:Reaction mixture containing 100 mM Tris-HCl buffer (pH 8) and COX-1 (ovine) or COX-2 (human recombinant) was preincubated for 10 min in a water bath ...More data for this Ligand-Target Pair
Affinity DataIC50: 5.66E+4nMpH: 8.0 T: 2°CAssay Description:Reaction mixture containing 100 mM Tris-HCl buffer (pH 8) and COX-1 (ovine) or COX-2 (human recombinant) was preincubated for 10 min in a water bath ...More data for this Ligand-Target Pair
Affinity DataIC50: 7.07E+4nMpH: 8.0 T: 2°CAssay Description:Reaction mixture containing 100 mM Tris-HCl buffer (pH 8) and COX-1 (ovine) or COX-2 (human recombinant) was preincubated for 10 min in a water bath ...More data for this Ligand-Target Pair
Affinity DataIC50: 9.49E+4nMpH: 8.0 T: 2°CAssay Description:Reaction mixture containing 100 mM Tris-HCl buffer (pH 8) and COX-1 (ovine) or COX-2 (human recombinant) was preincubated for 10 min in a water bath ...More data for this Ligand-Target Pair
Affinity DataIC50: 4.61E+4nMpH: 8.0 T: 2°CAssay Description:Reaction mixture containing 100 mM Tris-HCl buffer (pH 8) and COX-1 (ovine) or COX-2 (human recombinant) was preincubated for 10 min in a water bath ...More data for this Ligand-Target Pair
Affinity DataIC50: 9.64E+4nMpH: 8.0 T: 2°CAssay Description:Reaction mixture containing 100 mM Tris-HCl buffer (pH 8) and COX-1 (ovine) or COX-2 (human recombinant) was preincubated for 10 min in a water bath ...More data for this Ligand-Target Pair
Affinity DataIC50: 3.24E+3nMpH: 8.0 T: 2°CAssay Description:Reaction mixture containing 100 mM Tris-HCl buffer (pH 8) and COX-1 (ovine) or COX-2 (human recombinant) was preincubated for 10 min in a water bath ...More data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+4nMpH: 8.0 T: 2°CAssay Description:Tested compounds (50 uM), DuP-597 (0.5 uM; positive control), 11f and 11eie(1 nM - 200 uM ) or vehicle were pre-incubated with COX-FIS assay buffer (...More data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+4nMpH: 8.0 T: 2°CAssay Description:Tested compounds (50 uM), DuP-597 (0.5 uM; positive control), 11f and 11eie(1 nM - 200 uM ) or vehicle were pre-incubated with COX-FIS assay buffer (...More data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+4nMpH: 8.0 T: 2°CAssay Description:Tested compounds (50 uM), DuP-597 (0.5 uM; positive control), 11f and 11eie(1 nM - 200 uM ) or vehicle were pre-incubated with COX-FIS assay buffer (...More data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+4nMpH: 8.0 T: 2°CAssay Description:Tested compounds (50 uM), DuP-597 (0.5 uM; positive control), 11f and 11eie(1 nM - 200 uM ) or vehicle were pre-incubated with COX-FIS assay buffer (...More data for this Ligand-Target Pair
Affinity DataIC50: 1.45E+4nMpH: 8.0 T: 2°CAssay Description:Tested compounds (50 uM), DuP-597 (0.5 uM; positive control), 11f and 11eie(1 nM - 200 uM ) or vehicle were pre-incubated with COX-FIS assay buffer (...More data for this Ligand-Target Pair
Affinity DataIC50: 8.90E+3nMpH: 8.0 T: 2°CAssay Description:Tested compounds (50 uM), DuP-597 (0.5 uM; positive control), 11f and 11eie(1 nM - 200 uM ) or vehicle were pre-incubated with COX-FIS assay buffer (...More data for this Ligand-Target Pair
Affinity DataIC50: 68nMpH: 8.0 T: 2°CAssay Description:Tested compounds (50 uM), DuP-597 (0.5 uM; positive control), 11f and 11eie(1 nM - 200 uM ) or vehicle were pre-incubated with COX-FIS assay buffer (...More data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+4nMpH: 8.0 T: 2°CAssay Description:Tested compounds (50 uM), DuP-597 (0.5 uM; positive control), 11f and 11eie(1 nM - 200 uM ) or vehicle were pre-incubated with COX-FIS assay buffer (...More data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+4nMpH: 8.0 T: 2°CAssay Description:Tested compounds (50 uM), DuP-597 (0.5 uM; positive control), 11f and 11eie(1 nM - 200 uM ) or vehicle were pre-incubated with COX-FIS assay buffer (...More data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+4nMpH: 8.0 T: 2°CAssay Description:Tested compounds (50 uM), DuP-597 (0.5 uM; positive control), 11f and 11eie(1 nM - 200 uM ) or vehicle were pre-incubated with COX-FIS assay buffer (...More data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+4nMpH: 8.0 T: 2°CAssay Description:Tested compounds (50 uM), DuP-597 (0.5 uM; positive control), 11f and 11eie(1 nM - 200 uM ) or vehicle were pre-incubated with COX-FIS assay buffer (...More data for this Ligand-Target Pair
Affinity DataIC50: 2.20E+3nMpH: 8.0 T: 2°CAssay Description:Tested compounds (50 uM), DuP-597 (0.5 uM; positive control), 11f and 11eie(1 nM - 200 uM ) or vehicle were pre-incubated with COX-FIS assay buffer (...More data for this Ligand-Target Pair
Affinity DataIC50: 800nMpH: 8.0 T: 2°CAssay Description:Tested compounds (50 uM), DuP-597 (0.5 uM; positive control), 11f and 11eie(1 nM - 200 uM ) or vehicle were pre-incubated with COX-FIS assay buffer (...More data for this Ligand-Target Pair
Affinity DataIC50: 71nMpH: 8.0 T: 2°CAssay Description:Tested compounds (50 uM), DuP-597 (0.5 uM; positive control), 11f and 11eie(1 nM - 200 uM ) or vehicle were pre-incubated with COX-FIS assay buffer (...More data for this Ligand-Target Pair
Affinity DataIC50: 2.12E+3nMpH: 8.0 T: 2°CAssay Description:The reaction mixture contained reaction buffer solution (950 uL, 0.1 M Tris-HCl, pH 8.0 containing 5 mM EDTA and 2 mM phenol), COX-1 or COX-2 (10 uL)...More data for this Ligand-Target Pair
Affinity DataIC50: 3.51E+3nMpH: 8.0 T: 2°CAssay Description:The reaction mixture contained reaction buffer solution (950 uL, 0.1 M Tris-HCl, pH 8.0 containing 5 mM EDTA and 2 mM phenol), COX-1 or COX-2 (10 uL)...More data for this Ligand-Target Pair
Affinity DataIC50: 5.68E+3nMpH: 8.0 T: 2°CAssay Description:The reaction mixture contained reaction buffer solution (950 uL, 0.1 M Tris-HCl, pH 8.0 containing 5 mM EDTA and 2 mM phenol), COX-1 or COX-2 (10 uL)...More data for this Ligand-Target Pair
Affinity DataIC50: 2.26E+3nMpH: 8.0 T: 2°CAssay Description:The reaction mixture contained reaction buffer solution (950 uL, 0.1 M Tris-HCl, pH 8.0 containing 5 mM EDTA and 2 mM phenol), COX-1 or COX-2 (10 uL)...More data for this Ligand-Target Pair
Affinity DataIC50: 1.73E+3nMpH: 8.0 T: 2°CAssay Description:The reaction mixture contained reaction buffer solution (950 uL, 0.1 M Tris-HCl, pH 8.0 containing 5 mM EDTA and 2 mM phenol), COX-1 or COX-2 (10 uL)...More data for this Ligand-Target Pair
Affinity DataIC50: 2.65E+3nMpH: 8.0 T: 2°CAssay Description:The reaction mixture contained reaction buffer solution (950 uL, 0.1 M Tris-HCl, pH 8.0 containing 5 mM EDTA and 2 mM phenol), COX-1 or COX-2 (10 uL)...More data for this Ligand-Target Pair
Affinity DataIC50: 3.64E+3nMpH: 8.0 T: 2°CAssay Description:The reaction mixture contained reaction buffer solution (950 uL, 0.1 M Tris-HCl, pH 8.0 containing 5 mM EDTA and 2 mM phenol), COX-1 or COX-2 (10 uL)...More data for this Ligand-Target Pair
Affinity DataIC50: 2.46E+3nMpH: 8.0 T: 2°CAssay Description:The reaction mixture contained reaction buffer solution (950 uL, 0.1 M Tris-HCl, pH 8.0 containing 5 mM EDTA and 2 mM phenol), COX-1 or COX-2 (10 uL)...More data for this Ligand-Target Pair
Affinity DataIC50: 1.17E+4nMpH: 8.0 T: 2°CAssay Description:The reaction mixture contained reaction buffer solution (950 uL, 0.1 M Tris-HCl, pH 8.0 containing 5 mM EDTA and 2 mM phenol), COX-1 or COX-2 (10 uL)...More data for this Ligand-Target Pair
Affinity DataIC50: 1.68E+3nMpH: 8.0 T: 2°CAssay Description:The reaction mixture contained reaction buffer solution (950 uL, 0.1 M Tris-HCl, pH 8.0 containing 5 mM EDTA and 2 mM phenol), COX-1 or COX-2 (10 uL)...More data for this Ligand-Target Pair
Affinity DataIC50: 2.22E+3nMpH: 8.0 T: 2°CAssay Description:The reaction mixture contained reaction buffer solution (950 uL, 0.1 M Tris-HCl, pH 8.0 containing 5 mM EDTA and 2 mM phenol), COX-1 or COX-2 (10 uL)...More data for this Ligand-Target Pair
Affinity DataIC50: 1.76E+3nMpH: 8.0 T: 2°CAssay Description:The reaction mixture contained reaction buffer solution (950 uL, 0.1 M Tris-HCl, pH 8.0 containing 5 mM EDTA and 2 mM phenol), COX-1 or COX-2 (10 uL)...More data for this Ligand-Target Pair
Affinity DataIC50: 220nMpH: 8.0 T: 2°CAssay Description:The reaction mixture contained reaction buffer solution (950 uL, 0.1 M Tris-HCl, pH 8.0 containing 5 mM EDTA and 2 mM phenol), COX-1 or COX-2 (10 uL)...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMpH: 8.0 T: 2°CAssay Description:Reaction mixtures were prepared in 100 mM Tris¿HCl buffer, pH 8.0 containing 1 µM heme and COX-1 or COX-2 and preincubated for 10 min in a waterbath ...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMpH: 8.0 T: 2°CAssay Description:Reaction mixtures were prepared in 100 mM Tris¿HCl buffer, pH 8.0 containing 1 µM heme and COX-1 or COX-2 and preincubated for 10 min in a waterbath ...More data for this Ligand-Target Pair
