BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 11 hits of ph data with Target = 'Prostanoid EP2 Receptor'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Prostanoid EP2 Receptor


(Mus musculus (Mouse))
BDBM35848
PNG
(acrylic acid derivative, 6)
Show SMILES Cc1c(C)c2OC(C)(CCOc3ccccc3\C=C\C(O)=O)CCc2c(C)c1O
Show InChI InChI=1S/C24H28O5/c1-15-16(2)23-19(17(3)22(15)27)11-12-24(4,29-23)13-14-28-20-8-6-5-7-18(20)9-10-21(25)26/h5-10,27H,11-14H2,1-4H3,(H,25,26)/b10-9+
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
1.20E+3 -33.8n/an/an/an/an/a6.025



Ono Pharmaceutical Co., Ltd



Assay Description
Competitive binding studies were conducted using radiolabeled ligands and membrane fractions prepared from Chinese hamster ovary (CHO) cells stably e...


Bioorg Med Chem 17: 6567-82 (2009)


Article DOI: 10.1016/j.bmc.2009.08.007
BindingDB Entry DOI: 10.7270/Q23T9FK7
More data for this
Ligand-Target Pair
Prostanoid EP2 Receptor


(Mus musculus (Mouse))
BDBM35855
PNG
(acrylic acid derivative, 4)
Show SMILES OC(=O)\C=C\c1ccc(Cn2cccn2)cc1OCCc1ccc2ccccc2c1
Show InChI InChI=1S/C25H22N2O3/c28-25(29)11-10-22-9-7-20(18-27-14-3-13-26-27)17-24(22)30-15-12-19-6-8-21-4-1-2-5-23(21)16-19/h1-11,13-14,16-17H,12,15,18H2,(H,28,29)/b11-10+
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents

Article
PubMed
3.30E+3 -31.3n/an/an/an/an/a6.025



Ono Pharmaceutical Co., Ltd



Assay Description
Competitive binding studies were conducted using radiolabeled ligands and membrane fractions prepared from Chinese hamster ovary (CHO) cells stably e...


Bioorg Med Chem 17: 6567-82 (2009)


Article DOI: 10.1016/j.bmc.2009.08.007
BindingDB Entry DOI: 10.7270/Q23T9FK7
More data for this
Ligand-Target Pair
Prostanoid EP2 Receptor


(Mus musculus (Mouse))
BDBM35849
PNG
(acrylic acid derivative, 7)
Show SMILES Cc1ccc(\C=C\C(O)=O)c(OCCC2(C)CCc3c(C)c(O)c(C)c(C)c3O2)c1
Show InChI InChI=1S/C25H30O5/c1-15-6-7-19(8-9-22(26)27)21(14-15)29-13-12-25(5)11-10-20-18(4)23(28)16(2)17(3)24(20)30-25/h6-9,14,28H,10-13H2,1-5H3,(H,26,27)/b9-8+
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
5.70E+3 -29.9n/an/an/an/an/a6.025



Ono Pharmaceutical Co., Ltd



Assay Description
Competitive binding studies were conducted using radiolabeled ligands and membrane fractions prepared from Chinese hamster ovary (CHO) cells stably e...


Bioorg Med Chem 17: 6567-82 (2009)


Article DOI: 10.1016/j.bmc.2009.08.007
BindingDB Entry DOI: 10.7270/Q23T9FK7
More data for this
Ligand-Target Pair
Prostanoid EP2 Receptor


(Mus musculus (Mouse))
BDBM35856
PNG
(acrylic acid derivative, 13)
Show SMILES OC(=O)\C=C\c1ccc(CN2CCCC2=O)cc1OCCc1ccc2ccccc2c1
Show InChI InChI=1S/C26H25NO4/c28-25-6-3-14-27(25)18-20-8-10-22(11-12-26(29)30)24(17-20)31-15-13-19-7-9-21-4-1-2-5-23(21)16-19/h1-2,4-5,7-12,16-17H,3,6,13-15,18H2,(H,29,30)/b12-11+
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents

Article
PubMed
5.90E+3 -29.8n/an/an/an/an/a6.025



Ono Pharmaceutical Co., Ltd



Assay Description
Competitive binding studies were conducted using radiolabeled ligands and membrane fractions prepared from Chinese hamster ovary (CHO) cells stably e...


Bioorg Med Chem 17: 6567-82 (2009)


Article DOI: 10.1016/j.bmc.2009.08.007
BindingDB Entry DOI: 10.7270/Q23T9FK7
More data for this
Ligand-Target Pair
Prostanoid EP2 Receptor


(Mus musculus (Mouse))
BDBM35850
PNG
(acrylic acid derivative, 8)
Show SMILES COc1ccc(\C=C\C(O)=O)c(OCCC2(C)CCc3c(C)c(O)c(C)c(C)c3O2)c1
Show InChI InChI=1S/C25H30O6/c1-15-16(2)24-20(17(3)23(15)28)10-11-25(4,31-24)12-13-30-21-14-19(29-5)8-6-18(21)7-9-22(26)27/h6-9,14,28H,10-13H2,1-5H3,(H,26,27)/b9-7+
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
6.80E+3 -29.5n/an/an/an/an/a6.025



Ono Pharmaceutical Co., Ltd



Assay Description
Competitive binding studies were conducted using radiolabeled ligands and membrane fractions prepared from Chinese hamster ovary (CHO) cells stably e...


Bioorg Med Chem 17: 6567-82 (2009)


Article DOI: 10.1016/j.bmc.2009.08.007
BindingDB Entry DOI: 10.7270/Q23T9FK7
More data for this
Ligand-Target Pair
Prostanoid EP2 Receptor


(Mus musculus (Mouse))
BDBM35854
PNG
(acrylic acid derivative, 12)
Show SMILES OC(=O)\C=C\c1ccc(Cn2ccnc2)cc1OCCc1ccc2ccccc2c1
Show InChI InChI=1S/C25H22N2O3/c28-25(29)10-9-22-8-6-20(17-27-13-12-26-18-27)16-24(22)30-14-11-19-5-7-21-3-1-2-4-23(21)15-19/h1-10,12-13,15-16,18H,11,14,17H2,(H,28,29)/b10-9+
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
>1.00E+4>-28.5n/an/an/an/an/a6.025



Ono Pharmaceutical Co., Ltd



Assay Description
Competitive binding studies were conducted using radiolabeled ligands and membrane fractions prepared from Chinese hamster ovary (CHO) cells stably e...


Bioorg Med Chem 17: 6567-82 (2009)


Article DOI: 10.1016/j.bmc.2009.08.007
BindingDB Entry DOI: 10.7270/Q23T9FK7
More data for this
Ligand-Target Pair
Prostanoid EP2 Receptor


(Mus musculus (Mouse))
BDBM35853
PNG
(acrylic acid derivative, 11)
Show SMILES OC(=O)\C=C\c1ccc(Cn2ccnc2)cc1OCCc1cc2ccccc2o1
Show InChI InChI=1S/C23H20N2O4/c26-23(27)8-7-18-6-5-17(15-25-11-10-24-16-25)13-22(18)28-12-9-20-14-19-3-1-2-4-21(19)29-20/h1-8,10-11,13-14,16H,9,12,15H2,(H,26,27)/b8-7+
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents

Article
PubMed
>1.00E+4>-28.5n/an/an/an/an/a6.025



Ono Pharmaceutical Co., Ltd



Assay Description
Competitive binding studies were conducted using radiolabeled ligands and membrane fractions prepared from Chinese hamster ovary (CHO) cells stably e...


Bioorg Med Chem 17: 6567-82 (2009)


Article DOI: 10.1016/j.bmc.2009.08.007
BindingDB Entry DOI: 10.7270/Q23T9FK7
More data for this
Ligand-Target Pair
Prostanoid EP2 Receptor


(Mus musculus (Mouse))
BDBM35857
PNG
(acrylic acid derivative, 14)
Show SMILES OC(=O)\C=C\c1ccc(Cc2ccccc2)cc1OCCc1ccc2ccccc2c1
Show InChI InChI=1S/C28H24O3/c29-28(30)15-14-25-13-11-23(18-21-6-2-1-3-7-21)20-27(25)31-17-16-22-10-12-24-8-4-5-9-26(24)19-22/h1-15,19-20H,16-18H2,(H,29,30)/b15-14+
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
>1.00E+4>-28.5n/an/an/an/an/a6.025



Ono Pharmaceutical Co., Ltd



Assay Description
Competitive binding studies were conducted using radiolabeled ligands and membrane fractions prepared from Chinese hamster ovary (CHO) cells stably e...


Bioorg Med Chem 17: 6567-82 (2009)


Article DOI: 10.1016/j.bmc.2009.08.007
BindingDB Entry DOI: 10.7270/Q23T9FK7
More data for this
Ligand-Target Pair
Prostanoid EP2 Receptor


(Mus musculus (Mouse))
BDBM35851
PNG
(acrylic acid derivative, 9)
Show SMILES OC(=O)\C=C\c1ccc(Cn2ccnc2)cc1OCCCOc1ccccc1
Show InChI InChI=1S/C22H22N2O4/c25-22(26)10-9-19-8-7-18(16-24-12-11-23-17-24)15-21(19)28-14-4-13-27-20-5-2-1-3-6-20/h1-3,5-12,15,17H,4,13-14,16H2,(H,25,26)/b10-9+
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
>1.00E+4>-28.5n/an/an/an/an/a6.025



Ono Pharmaceutical Co., Ltd



Assay Description
Competitive binding studies were conducted using radiolabeled ligands and membrane fractions prepared from Chinese hamster ovary (CHO) cells stably e...


Bioorg Med Chem 17: 6567-82 (2009)


Article DOI: 10.1016/j.bmc.2009.08.007
BindingDB Entry DOI: 10.7270/Q23T9FK7
More data for this
Ligand-Target Pair
Prostanoid EP2 Receptor


(Mus musculus (Mouse))
BDBM35846
PNG
(acrylic acid derivative, 3)
Show SMILES Cc1c(C)c2OC(C)(CCOc3cc(Cn4ccnc4)ccc3\C=C\C(O)=O)CCc2c(C)c1O
Show InChI InChI=1S/C28H32N2O5/c1-18-19(2)27-23(20(3)26(18)33)9-10-28(4,35-27)11-14-34-24-15-21(16-30-13-12-29-17-30)5-6-22(24)7-8-25(31)32/h5-8,12-13,15,17,33H,9-11,14,16H2,1-4H3,(H,31,32)/b8-7+
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents

Article
PubMed
>1.00E+4>-28.5n/an/an/an/an/a6.025



Ono Pharmaceutical Co., Ltd



Assay Description
Competitive binding studies were conducted using radiolabeled ligands and membrane fractions prepared from Chinese hamster ovary (CHO) cells stably e...


Bioorg Med Chem 17: 6567-82 (2009)


Article DOI: 10.1016/j.bmc.2009.08.007
BindingDB Entry DOI: 10.7270/Q23T9FK7
More data for this
Ligand-Target Pair
Prostanoid EP2 Receptor


(Mus musculus (Mouse))
BDBM35852
PNG
(acrylic acid derivative, 10)
Show SMILES OC(=O)\C=C\c1ccc(Cn2ccnc2)cc1OCCCCOc1ccccc1
Show InChI InChI=1S/C23H24N2O4/c26-23(27)11-10-20-9-8-19(17-25-13-12-24-18-25)16-22(20)29-15-5-4-14-28-21-6-2-1-3-7-21/h1-3,6-13,16,18H,4-5,14-15,17H2,(H,26,27)/b11-10+
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
>1.00E+4>-28.5n/an/an/an/an/a6.025



Ono Pharmaceutical Co., Ltd



Assay Description
Competitive binding studies were conducted using radiolabeled ligands and membrane fractions prepared from Chinese hamster ovary (CHO) cells stably e...


Bioorg Med Chem 17: 6567-82 (2009)


Article DOI: 10.1016/j.bmc.2009.08.007
BindingDB Entry DOI: 10.7270/Q23T9FK7
More data for this
Ligand-Target Pair