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Compile Data Set for Download or QSAR

Found 5 hits of ph data with Target = 'Protein Tyrosine Phosphatase PTPB'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Protein Tyrosine Phosphatase PTPB


(Mycobacterium tuberculosis)
BDBM26104
PNG
(5-{2-cyclohexyl-4-[4-fluoro-3-(trifluoromethyl)phe...)
Show SMILES OC(=O)c1cc(on1)-c1ccc(cc1C1CCCCC1)-c1ccc(F)c(c1)C(F)(F)F
Show InChI InChI=1S/C23H19F4NO3/c24-19-9-7-15(11-18(19)23(25,26)27)14-6-8-16(21-12-20(22(29)30)28-31-21)17(10-14)13-4-2-1-3-5-13/h6-13H,1-5H2,(H,29,30)
PDB
MMDB

KEGG

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
220 -37.6n/an/an/an/an/a7.422



University of California at Berkeley



Assay Description
The reaction was started by addition of pNPP substrate, and reaction progress was monitored at 405 nm. The initial rate data collected was used for d...


J Am Chem Soc 129: 9613-5 (2007)


Article DOI: 10.1021/ja0727520
BindingDB Entry DOI: 10.7270/Q2PG1Q2M
More data for this
Ligand-Target Pair
Protein Tyrosine Phosphatase PTPB


(Mycobacterium tuberculosis)
BDBM26103
PNG
(5-{4-[4-fluoro-3-(trifluoromethyl)phenyl]-2-(propa...)
Show SMILES CC(C)c1cc(ccc1-c1cc(no1)C(O)=O)-c1ccc(F)c(c1)C(F)(F)F
Show InChI InChI=1S/C20H15F4NO3/c1-10(2)14-7-11(12-4-6-16(21)15(8-12)20(22,23)24)3-5-13(14)18-9-17(19(26)27)25-28-18/h3-10H,1-2H3,(H,26,27)
PDB
MMDB

KEGG

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
500 -35.6n/an/an/an/an/a7.422



University of California at Berkeley



Assay Description
The reaction was started by addition of pNPP substrate, and reaction progress was monitored at 405 nm. The initial rate data collected was used for d...


J Am Chem Soc 129: 9613-5 (2007)


Article DOI: 10.1021/ja0727520
BindingDB Entry DOI: 10.7270/Q2PG1Q2M
More data for this
Ligand-Target Pair
Protein Tyrosine Phosphatase PTPB


(Mycobacterium tuberculosis)
BDBM26102
PNG
(5-[2-(propan-2-yl)-4-[3-(trifluoromethyl)phenyl]ph...)
Show SMILES CC(C)c1cc(ccc1-c1cc(no1)C(O)=O)-c1cccc(c1)C(F)(F)F
Show InChI InChI=1S/C20H16F3NO3/c1-11(2)16-9-13(12-4-3-5-14(8-12)20(21,22)23)6-7-15(16)18-10-17(19(25)26)24-27-18/h3-11H,1-2H3,(H,25,26)
PDB
MMDB

KEGG

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
850 -34.3n/an/an/an/an/a7.422



University of California at Berkeley



Assay Description
The reaction was started by addition of pNPP substrate, and reaction progress was monitored at 405 nm. The initial rate data collected was used for d...


J Am Chem Soc 129: 9613-5 (2007)


Article DOI: 10.1021/ja0727520
BindingDB Entry DOI: 10.7270/Q2PG1Q2M
More data for this
Ligand-Target Pair
Protein Tyrosine Phosphatase PTPB


(Mycobacterium tuberculosis)
BDBM26101
PNG
(5-{4-[3-(trifluoromethyl)phenyl]phenyl}-1,2-oxazol...)
Show SMILES OC(=O)c1cc(on1)-c1ccc(cc1)-c1cccc(c1)C(F)(F)F
Show InChI InChI=1S/C17H10F3NO3/c18-17(19,20)13-3-1-2-12(8-13)10-4-6-11(7-5-10)15-9-14(16(22)23)21-24-15/h1-9H,(H,22,23)
PDB
MMDB

KEGG

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
2.50E+3 -31.7n/an/an/an/an/a7.422



University of California at Berkeley



Assay Description
The reaction was started by addition of pNPP substrate, and reaction progress was monitored at 405 nm. The initial rate data collected was used for d...


J Am Chem Soc 129: 9613-5 (2007)


Article DOI: 10.1021/ja0727520
BindingDB Entry DOI: 10.7270/Q2PG1Q2M
More data for this
Ligand-Target Pair
Protein Tyrosine Phosphatase PTPB


(Mycobacterium tuberculosis)
BDBM26099
PNG
(5-{4-[3-(trifluoromethyl)phenyl]phenyl}-1,2-thiazo...)
Show SMILES FC(F)(F)c1cccc(c1)-c1ccc(cc1)C1CC(=O)NS1(=O)=O
Show InChI InChI=1S/C16H12F3NO3S/c17-16(18,19)13-3-1-2-12(8-13)10-4-6-11(7-5-10)14-9-15(21)20-24(14,22)23/h1-8,14H,9H2,(H,20,21)
PDB
MMDB

KEGG

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
8.80E+3 -28.6n/an/an/an/an/a7.422



University of California at Berkeley



Assay Description
The reaction was started by addition of pNPP substrate, and reaction progress was monitored at 405 nm. The initial rate data collected was used for d...


J Am Chem Soc 129: 9613-5 (2007)


Article DOI: 10.1021/ja0727520
BindingDB Entry DOI: 10.7270/Q2PG1Q2M
More data for this
Ligand-Target Pair