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Compile Data Set for Download or QSAR

Found 8 hits of ph data with Target = 'Protein kinase C, eta'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Protein kinase C, eta


(Homo sapiens (human))
BDBM3181
PNG
(2-[[2,6-Dihydroxy-4-[[2-[[(4-hydroxyphenyl)carbony...)
Show SMILES OC(=O)c1cccc(O)c1C(=O)c1c(O)cc(cc1O)C(=O)OCCNC(=O)c1ccc(O)cc1
Show InChI InChI=1S/C24H19NO10/c26-14-6-4-12(5-7-14)22(31)25-8-9-35-24(34)13-10-17(28)20(18(29)11-13)21(30)19-15(23(32)33)2-1-3-16(19)27/h1-7,10-11,26-29H,8-9H2,(H,25,31)(H,32,33)
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Article
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n/an/a 230n/an/an/an/a7.530



Sphinx Laboratories



Assay Description
PKC was assayed by quantitating the incorporation of 32P from [gamma-32P]ATP into histone type IIIs.


J Med Chem 39: 5215-27 (1996)


Article DOI: 10.1021/jm960581w
BindingDB Entry DOI: 10.7270/Q2G73BVV
More data for this
Ligand-Target Pair
Protein kinase C, eta


(Homo sapiens (human))
BDBM3182
PNG
(2-({2,6-dihydroxy-4-[({3-[(4-hydroxybenzene)amido]...)
Show SMILES OC(=O)c1cccc(O)c1C(=O)c1c(O)cc(cc1O)C(=O)OC1CCCNCC1NC(=O)c1ccc(O)cc1
Show InChI InChI=1S/C28H26N2O10/c31-16-8-6-14(7-9-16)26(36)30-18-13-29-10-2-5-22(18)40-28(39)15-11-20(33)24(21(34)12-15)25(35)23-17(27(37)38)3-1-4-19(23)32/h1,3-4,6-9,11-12,18,22,29,31-34H,2,5,10,13H2,(H,30,36)(H,37,38)
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n/an/a 20n/an/an/an/a7.530



Sphinx Laboratories



Assay Description
PKC was assayed by quantitating the incorporation of 32P from [gamma-32P]ATP into histone type IIIs.


J Med Chem 39: 5215-27 (1996)


Article DOI: 10.1021/jm960581w
BindingDB Entry DOI: 10.7270/Q2G73BVV
More data for this
Ligand-Target Pair
Protein kinase C, eta


(Homo sapiens (human))
BDBM3183
PNG
(2-({2,6-dihydroxy-4-[({2-[(4-hydroxybenzene)amido]...)
Show SMILES OC(=O)c1cccc(O)c1C(=O)c1c(O)cc(cc1O)C(=O)OC1CCCC1NC(=O)c1ccc(O)cc1
Show InChI InChI=1S/C27H23NO10/c29-15-9-7-13(8-10-15)25(34)28-17-4-2-6-21(17)38-27(37)14-11-19(31)23(20(32)12-14)24(33)22-16(26(35)36)3-1-5-18(22)30/h1,3,5,7-12,17,21,29-32H,2,4,6H2,(H,28,34)(H,35,36)
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n/an/a 0.600n/an/an/an/a7.530



Sphinx Laboratories



Assay Description
PKC was assayed by quantitating the incorporation of 32P from [gamma-32P]ATP into histone type IIIs.


J Med Chem 39: 5215-27 (1996)


Article DOI: 10.1021/jm960581w
BindingDB Entry DOI: 10.7270/Q2G73BVV
More data for this
Ligand-Target Pair
Protein kinase C, eta


(Homo sapiens (human))
BDBM3245
PNG
((3R,4R)-4-[(4-hydroxybenzene)amido]pyrrolidin-3-yl...)
Show SMILES CCCCOC(=O)c1cccc(O)c1C(=O)c1c(O)cc(cc1O)C(=O)O[C@@H]1CNC[C@H]1NC(=O)c1ccc(O)cc1
Show InChI InChI=1S/C30H30N2O10/c1-2-3-11-41-30(40)19-5-4-6-21(34)25(19)27(37)26-22(35)12-17(13-23(26)36)29(39)42-24-15-31-14-20(24)32-28(38)16-7-9-18(33)10-8-16/h4-10,12-13,20,24,31,33-36H,2-3,11,14-15H2,1H3,(H,32,38)/t20-,24-/m1/s1
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n/an/a 40n/an/an/an/a7.530



Sphinx Pharmaceuticals



Assay Description
The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...


Bioorg Med Chem Lett 5: 2133-8 (1995)


Article DOI: 10.1016/j.bmcl.2005.09.037
BindingDB Entry DOI: 10.7270/Q26T0JT4
More data for this
Ligand-Target Pair
Protein kinase C, eta


(Homo sapiens (human))
BDBM3152
PNG
(2-{[2,6-dihydroxy-4-({[(3R,4R)-4-[(4-hydroxybenzen...)
Show SMILES OC(=O)c1cccc(O)c1C(=O)c1c(O)cc(cc1O)C(=O)O[C@@H]1CNC[C@H]1NC(=O)c1ccc(O)cc1
Show InChI InChI=1S/C26H22N2O10/c29-14-6-4-12(5-7-14)24(34)28-16-10-27-11-20(16)38-26(37)13-8-18(31)22(19(32)9-13)23(33)21-15(25(35)36)2-1-3-17(21)30/h1-9,16,20,27,29-32H,10-11H2,(H,28,34)(H,35,36)/t16-,20-/m1/s1
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n/an/a 4n/an/an/an/a7.530



Sphinx Pharmaceuticals



Assay Description
The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...


Bioorg Med Chem Lett 5: 2133-8 (1995)


Article DOI: 10.1016/j.bmcl.2005.09.037
BindingDB Entry DOI: 10.7270/Q26T0JT4
More data for this
Ligand-Target Pair
Protein kinase C, eta


(Homo sapiens (human))
BDBM3243
PNG
((3R,4R)-4-[(4-hydroxybenzene)amido]pyrrolidin-3-yl...)
Show SMILES COC(=O)c1cccc(O)c1C(=O)c1c(O)cc(cc1O)C(=O)O[C@@H]1CNC[C@H]1NC(=O)c1ccc(O)cc1
Show InChI InChI=1S/C27H24N2O10/c1-38-27(37)16-3-2-4-18(31)22(16)24(34)23-19(32)9-14(10-20(23)33)26(36)39-21-12-28-11-17(21)29-25(35)13-5-7-15(30)8-6-13/h2-10,17,21,28,30-33H,11-12H2,1H3,(H,29,35)/t17-,21-/m1/s1
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n/an/a 16n/an/an/an/a7.530



Sphinx Pharmaceuticals



Assay Description
The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...


Bioorg Med Chem Lett 5: 2133-8 (1995)


Article DOI: 10.1016/j.bmcl.2005.09.037
BindingDB Entry DOI: 10.7270/Q26T0JT4
More data for this
Ligand-Target Pair
Protein kinase C, eta


(Homo sapiens (human))
BDBM3244
PNG
((3R,4R)-4-[(4-hydroxybenzene)amido]pyrrolidin-3-yl...)
Show SMILES CCOC(=O)c1cccc(O)c1C(=O)c1c(O)cc(cc1O)C(=O)O[C@@H]1CNC[C@H]1NC(=O)c1ccc(O)cc1
Show InChI InChI=1S/C28H26N2O10/c1-2-39-28(38)17-4-3-5-19(32)23(17)25(35)24-20(33)10-15(11-21(24)34)27(37)40-22-13-29-12-18(22)30-26(36)14-6-8-16(31)9-7-14/h3-11,18,22,29,31-34H,2,12-13H2,1H3,(H,30,36)/t18-,22-/m1/s1
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Sphinx Pharmaceuticals



Assay Description
The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...


Bioorg Med Chem Lett 5: 2133-8 (1995)


Article DOI: 10.1016/j.bmcl.2005.09.037
BindingDB Entry DOI: 10.7270/Q26T0JT4
More data for this
Ligand-Target Pair
Protein kinase C, eta


(Homo sapiens (human))
BDBM3149
PNG
(2-{[2,6-dihydroxy-4-({[(3R,4R)-3-[(4-hydroxybenzen...)
Show SMILES OC(=O)c1cccc(O)c1C(=O)c1c(O)cc(cc1O)C(=O)O[C@@H]1CCCNC[C@H]1NC(=O)c1ccc(O)cc1
Show InChI InChI=1S/C28H26N2O10/c31-16-8-6-14(7-9-16)26(36)30-18-13-29-10-2-5-22(18)40-28(39)15-11-20(33)24(21(34)12-15)25(35)23-17(27(37)38)3-1-4-19(23)32/h1,3-4,6-9,11-12,18,22,29,31-34H,2,5,10,13H2,(H,30,36)(H,37,38)/t18-,22-/m1/s1
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n/an/a 22n/an/an/an/a7.530



Sphinx Pharmaceuticals



Assay Description
The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...


Bioorg Med Chem Lett 5: 2133-8 (1995)


Article DOI: 10.1016/j.bmcl.2005.09.037
BindingDB Entry DOI: 10.7270/Q26T0JT4
More data for this
Ligand-Target Pair