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Compile Data Set for Download or QSAR

Found 216 hits of ph data with Target = 'Runt-Related Transcription Factor 1 Isoform AML1C'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Runt-Related Transcription Factor 1 Isoform AML1C


(Homo sapiens)
BDBM583
PNG
(4-amino-5-methoxy-9(10H)-acridinone | MLS000705222...)
Show SMILES COc1cccc2c1[nH]c1c(N)cccc1c2=O
Show InChI InChI=1S/C14H12N2O2/c1-18-11-7-3-5-9-13(11)16-12-8(14(9)17)4-2-6-10(12)15/h2-7H,15H2,1H3,(H,16,17)
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n/an/a 1.00E+5n/an/an/an/a7.423



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
This assay is to identify inhibitors of the protein-protein interaction between the RUNX1 Runt domain and CBFbeta-SMMHC. This is accomplished by usin...


PubChem Bioassay (2009)


BindingDB Entry DOI: 10.7270/Q2T72FSX
More data for this
Ligand-Target Pair
Runt-Related Transcription Factor 1 Isoform AML1C


(Homo sapiens)
BDBM29679
PNG
((E)-2-cyano-3-(5-methyl-2-furanyl)-N-(5-quinolinyl...)
Show SMILES Cc1ccc(\C=C(/C#N)C(=O)Nc2cccc3ncccc23)o1
Show InChI InChI=1S/C18H13N3O2/c1-12-7-8-14(23-12)10-13(11-19)18(22)21-17-6-2-5-16-15(17)4-3-9-20-16/h2-10H,1H3,(H,21,22)/b13-10+
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n/an/a 1.74E+4n/an/an/an/a7.423



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
This assay is to identify inhibitors of the protein-protein interaction between the RUNX1 Runt domain and CBFbeta-SMMHC. This is accomplished by usin...


PubChem Bioassay (2009)


BindingDB Entry DOI: 10.7270/Q2T72FSX
More data for this
Ligand-Target Pair
Runt-Related Transcription Factor 1 Isoform AML1C


(Homo sapiens)
BDBM29680
PNG
(2-[(6,7-dihydroxy-2-keto-chromen-4-yl)methylthio]-...)
Show SMILES COc1cccc(c1)-n1c(SCc2cc(=O)oc3cc(O)c(O)cc23)nc2ccccc2c1=O
Show InChI InChI=1S/C25H18N2O6S/c1-32-16-6-4-5-15(10-16)27-24(31)17-7-2-3-8-19(17)26-25(27)34-13-14-9-23(30)33-22-12-21(29)20(28)11-18(14)22/h2-12,28-29H,13H2,1H3
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n/an/a 1.93E+4n/an/an/an/a7.423



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
This assay is to identify inhibitors of the protein-protein interaction between the RUNX1 Runt domain and CBFbeta-SMMHC. This is accomplished by usin...


PubChem Bioassay (2009)


BindingDB Entry DOI: 10.7270/Q2T72FSX
More data for this
Ligand-Target Pair
Runt-Related Transcription Factor 1 Isoform AML1C


(Homo sapiens)
BDBM29681
PNG
(2-[(1,2,3,4-tetrafluoro-9-acridinyl)amino]ethanol ...)
Show SMILES OCCNc1c2ccccc2nc2c(F)c(F)c(F)c(F)c12
Show InChI InChI=1S/C15H10F4N2O/c16-10-9-14(20-5-6-22)7-3-1-2-4-8(7)21-15(9)13(19)12(18)11(10)17/h1-4,22H,5-6H2,(H,20,21)
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n/an/a 1.00E+5n/an/an/an/a7.423



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
This assay is to identify inhibitors of the protein-protein interaction between the RUNX1 Runt domain and CBFbeta-SMMHC. This is accomplished by usin...


PubChem Bioassay (2009)


BindingDB Entry DOI: 10.7270/Q2T72FSX
More data for this
Ligand-Target Pair
Runt-Related Transcription Factor 1 Isoform AML1C


(Homo sapiens)
BDBM29682
PNG
(2-(dichloromethyl)-7-(phenylmethyl)-3,5,6,8-tetrah...)
Show SMILES ClC(Cl)c1nc2sc3CN(Cc4ccccc4)CCc3c2c(=O)[nH]1
Show InChI InChI=1S/C17H15Cl2N3OS/c18-14(19)15-20-16(23)13-11-6-7-22(8-10-4-2-1-3-5-10)9-12(11)24-17(13)21-15/h1-5,14H,6-9H2,(H,20,21,23)
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n/an/a 1.34E+4n/an/an/an/a7.423



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
This assay is to identify inhibitors of the protein-protein interaction between the RUNX1 Runt domain and CBFbeta-SMMHC. This is accomplished by usin...


PubChem Bioassay (2009)


BindingDB Entry DOI: 10.7270/Q2T72FSX
More data for this
Ligand-Target Pair
Runt-Related Transcription Factor 1 Isoform AML1C


(Homo sapiens)
BDBM29683
PNG
(MLS000666106 | N-[3-cyano-1-(2-furanylmethyl)-5-ox...)
Show SMILES O=C(\N=c1/c(cc2c(nc3ccccn3c2=O)n1Cc1ccco1)C#N)c1ccco1
Show InChI InChI=1S/C22H13N5O4/c23-12-14-11-16-20(24-18-7-1-2-8-26(18)22(16)29)27(13-15-5-3-9-30-15)19(14)25-21(28)17-6-4-10-31-17/h1-11H,13H2/b25-19+
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n/an/a 5.61E+4n/an/an/an/a7.423



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
This assay is to identify inhibitors of the protein-protein interaction between the RUNX1 Runt domain and CBFbeta-SMMHC. This is accomplished by usin...


PubChem Bioassay (2009)


BindingDB Entry DOI: 10.7270/Q2T72FSX
More data for this
Ligand-Target Pair
Runt-Related Transcription Factor 1 Isoform AML1C


(Homo sapiens)
BDBM29684
PNG
((3E)-3-(2-furanylmethylidene)-1,2-dihydrocyclopent...)
Show SMILES CC1CCCCC1NC(=O)COC(=O)c1c2CC\C(=C/c3ccco3)c2nc2ccccc12
Show InChI InChI=1S/C27H28N2O4/c1-17-7-2-4-10-22(17)28-24(30)16-33-27(31)25-20-9-3-5-11-23(20)29-26-18(12-13-21(25)26)15-19-8-6-14-32-19/h3,5-6,8-9,11,14-15,17,22H,2,4,7,10,12-13,16H2,1H3,(H,28,30)/b18-15+
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n/an/a 1.06E+4n/an/an/an/a7.423



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
This assay is to identify inhibitors of the protein-protein interaction between the RUNX1 Runt domain and CBFbeta-SMMHC. This is accomplished by usin...


PubChem Bioassay (2009)


BindingDB Entry DOI: 10.7270/Q2T72FSX
More data for this
Ligand-Target Pair
Runt-Related Transcription Factor 1 Isoform AML1C


(Homo sapiens)
BDBM29685
PNG
((3E)-3-(2-furanylmethylidene)-1,2-dihydrocyclopent...)
Show SMILES O=C(COC(=O)c1c2CC\C(=C/c3ccco3)c2nc2ccccc12)NC1CCCC1
Show InChI InChI=1S/C25H24N2O4/c28-22(26-17-6-1-2-7-17)15-31-25(29)23-19-9-3-4-10-21(19)27-24-16(11-12-20(23)24)14-18-8-5-13-30-18/h3-5,8-10,13-14,17H,1-2,6-7,11-12,15H2,(H,26,28)/b16-14+
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n/an/a 1.04E+4n/an/an/an/a7.423



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
This assay is to identify inhibitors of the protein-protein interaction between the RUNX1 Runt domain and CBFbeta-SMMHC. This is accomplished by usin...


PubChem Bioassay (2009)


BindingDB Entry DOI: 10.7270/Q2T72FSX
More data for this
Ligand-Target Pair
Runt-Related Transcription Factor 1 Isoform AML1C


(Homo sapiens)
BDBM29686
PNG
((7-hydroxy-2-oxochromen-4-yl)methyl 2-(3-oxo-4H-1,...)
Show SMILES Oc1ccc2c(COC(=O)CC3Sc4ccccc4NC3=O)cc(=O)oc2c1
Show InChI InChI=1S/C20H15NO6S/c22-12-5-6-13-11(7-19(24)27-15(13)8-12)10-26-18(23)9-17-20(25)21-14-3-1-2-4-16(14)28-17/h1-8,17,22H,9-10H2,(H,21,25)
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n/an/a 1.96E+4n/an/an/an/a7.423



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
This assay is to identify inhibitors of the protein-protein interaction between the RUNX1 Runt domain and CBFbeta-SMMHC. This is accomplished by usin...


PubChem Bioassay (2009)


BindingDB Entry DOI: 10.7270/Q2T72FSX
More data for this
Ligand-Target Pair
Runt-Related Transcription Factor 1 Isoform AML1C


(Homo sapiens)
BDBM29687
PNG
(2-(1,2,3-thiadiazol-5-yl)-1,4-benzenediol | 2-(2,3...)
Show SMILES Oc1ccc(O)c(c1)-c1cnns1
Show InChI InChI=1S/C8H6N2O2S/c11-5-1-2-7(12)6(3-5)8-4-9-10-13-8/h1-4,11-12H
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n/an/a 2.05E+4n/an/an/an/a7.423



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
This assay is to identify inhibitors of the protein-protein interaction between the RUNX1 Runt domain and CBFbeta-SMMHC. This is accomplished by usin...


PubChem Bioassay (2009)


BindingDB Entry DOI: 10.7270/Q2T72FSX
More data for this
Ligand-Target Pair
Runt-Related Transcription Factor 1 Isoform AML1C


(Homo sapiens)
BDBM29688
PNG
(3-(9-(3-chloro-4-{[(4-methylphenyl)sulfonyl]oxy}ph...)
Show SMILES Cc1ccc(cc1)S(=O)(=O)Oc1ccc(cc1Cl)C1C2=C(CCCC2=O)N(CCC(O)=O)C2=C1C(=O)CCC2
Show InChI InChI=1S/C29H28ClNO7S/c1-17-8-11-19(12-9-17)39(36,37)38-25-13-10-18(16-20(25)30)27-28-21(4-2-6-23(28)32)31(15-14-26(34)35)22-5-3-7-24(33)29(22)27/h8-13,16,27H,2-7,14-15H2,1H3,(H,34,35)
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n/an/a 1.46E+4n/an/an/an/a7.423



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
This assay is to identify inhibitors of the protein-protein interaction between the RUNX1 Runt domain and CBFbeta-SMMHC. This is accomplished by usin...


PubChem Bioassay (2009)


BindingDB Entry DOI: 10.7270/Q2T72FSX
More data for this
Ligand-Target Pair
Runt-Related Transcription Factor 1 Isoform AML1C


(Homo sapiens)
BDBM29689
PNG
((4Z)-3-hydroxy-4-(2H-thiadiazol-5-ylidene)-1-cyclo...)
Show SMILES Oc1ccc(-c2cnns2)c(O)c1
Show InChI InChI=1S/C8H6N2O2S/c11-5-1-2-6(7(12)3-5)8-4-9-10-13-8/h1-4,11-12H
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n/an/a 1.99E+4n/an/an/an/a7.423



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
This assay is to identify inhibitors of the protein-protein interaction between the RUNX1 Runt domain and CBFbeta-SMMHC. This is accomplished by usin...


PubChem Bioassay (2009)


BindingDB Entry DOI: 10.7270/Q2T72FSX
More data for this
Ligand-Target Pair
Runt-Related Transcription Factor 1 Isoform AML1C


(Homo sapiens)
BDBM29690
PNG
(3-(9-(3-ethoxy-4-{[(4-methylphenyl)sulfonyl]oxy}ph...)
Show SMILES CCOc1cc(ccc1OS(=O)(=O)c1ccc(C)cc1)C1C2=C(CCCC2=O)N(CCC(O)=O)C2=C1C(=O)CCC2
Show InChI InChI=1S/C31H33NO8S/c1-3-39-27-18-20(12-15-26(27)40-41(37,38)21-13-10-19(2)11-14-21)29-30-22(6-4-8-24(30)33)32(17-16-28(35)36)23-7-5-9-25(34)31(23)29/h10-15,18,29H,3-9,16-17H2,1-2H3,(H,35,36)
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n/an/a 3.05E+4n/an/an/an/a7.423



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
This assay is to identify inhibitors of the protein-protein interaction between the RUNX1 Runt domain and CBFbeta-SMMHC. This is accomplished by usin...


PubChem Bioassay (2009)


BindingDB Entry DOI: 10.7270/Q2T72FSX
More data for this
Ligand-Target Pair
Runt-Related Transcription Factor 1 Isoform AML1C


(Homo sapiens)
BDBM29691
PNG
(9-(3-bromanyl-5-ethoxy-4-prop-2-enoxy-phenyl)-10-m...)
Show SMILES CCOc1cc(cc(Br)c1OCC=C)C1C2=C(CCCC2=O)N(C)C2=C1C(=O)CCC2
Show InChI InChI=1S/C25H28BrNO4/c1-4-12-31-25-16(26)13-15(14-21(25)30-5-2)22-23-17(8-6-10-19(23)28)27(3)18-9-7-11-20(29)24(18)22/h4,13-14,22H,1,5-12H2,2-3H3
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n/an/a 4.12E+4n/an/an/an/a7.423



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
This assay is to identify inhibitors of the protein-protein interaction between the RUNX1 Runt domain and CBFbeta-SMMHC. This is accomplished by usin...


PubChem Bioassay (2009)


BindingDB Entry DOI: 10.7270/Q2T72FSX
More data for this
Ligand-Target Pair
Runt-Related Transcription Factor 1 Isoform AML1C


(Homo sapiens)
BDBM29692
PNG
((2Z)-3-ethyl-2-[(E)-3-(3-ethyl-4,5-dihydro-1,3-thi...)
Show SMILES CCN1CCS\C1=C/C=C/C1=[N+](CC)CCS1
Show InChI InChI=1S/C13H21N2S2/c1-3-14-8-10-16-12(14)6-5-7-13-15(4-2)9-11-17-13/h5-7H,3-4,8-11H2,1-2H3/q+1
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n/an/a 1.00E+5n/an/an/an/a7.423



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
This assay is to identify inhibitors of the protein-protein interaction between the RUNX1 Runt domain and CBFbeta-SMMHC. This is accomplished by usin...


PubChem Bioassay (2009)


BindingDB Entry DOI: 10.7270/Q2T72FSX
More data for this
Ligand-Target Pair
Runt-Related Transcription Factor 1 Isoform AML1C


(Homo sapiens)
BDBM29693
PNG
(6-(4-chlorophenyl)-1H-pteridine-2,4-dione | 6-(4-c...)
Show SMILES Clc1ccc(cc1)-c1cnc2[nH]c(=O)[nH]c(=O)c2n1
Show InChI InChI=1S/C12H7ClN4O2/c13-7-3-1-6(2-4-7)8-5-14-10-9(15-8)11(18)17-12(19)16-10/h1-5H,(H2,14,16,17,18,19)
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n/an/a 1.00E+5n/an/an/an/a7.423



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
This assay is to identify inhibitors of the protein-protein interaction between the RUNX1 Runt domain and CBFbeta-SMMHC. This is accomplished by usin...


PubChem Bioassay (2009)


BindingDB Entry DOI: 10.7270/Q2T72FSX
More data for this
Ligand-Target Pair
Runt-Related Transcription Factor 1 Isoform AML1C


(Homo sapiens)
BDBM29694
PNG
(3-keto-N-(2-pyridylmethyl)benzo[f]chromene-2-carbo...)
Show SMILES O=C(NCc1ccccn1)c1cc2c(ccc3ccccc23)oc1=O
Show InChI InChI=1S/C20H14N2O3/c23-19(22-12-14-6-3-4-10-21-14)17-11-16-15-7-2-1-5-13(15)8-9-18(16)25-20(17)24/h1-11H,12H2,(H,22,23)
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n/an/a 1.00E+5n/an/an/an/a7.423



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
This assay is to identify inhibitors of the protein-protein interaction between the RUNX1 Runt domain and CBFbeta-SMMHC. This is accomplished by usin...


PubChem Bioassay (2009)


BindingDB Entry DOI: 10.7270/Q2T72FSX
More data for this
Ligand-Target Pair
Runt-Related Transcription Factor 1 Isoform AML1C


(Homo sapiens)
BDBM29695
PNG
(MLS000689748 | N-(2,5-dimethoxyphenyl)sulfonyl-N-(...)
Show SMILES COc1ccc(OC)c(c1)S(=O)(=O)N(C(C)=O)c1ccc2oc(=O)sc2c1
Show InChI InChI=1S/C17H15NO7S2/c1-10(19)18(11-4-6-13-15(8-11)26-17(20)25-13)27(21,22)16-9-12(23-2)5-7-14(16)24-3/h4-9H,1-3H3
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n/an/a 1.00E+5n/an/an/an/a7.423



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
This assay is to identify inhibitors of the protein-protein interaction between the RUNX1 Runt domain and CBFbeta-SMMHC. This is accomplished by usin...


PubChem Bioassay (2009)


BindingDB Entry DOI: 10.7270/Q2T72FSX
More data for this
Ligand-Target Pair
Runt-Related Transcription Factor 1 Isoform AML1C


(Homo sapiens)
BDBM29696
PNG
(1-[(4-methylphenyl)methyl]-3-(phenylmethyl)urea | ...)
Show SMILES Cc1ccc(CNC(=O)NCc2ccccc2)cc1
Show InChI InChI=1S/C16H18N2O/c1-13-7-9-15(10-8-13)12-18-16(19)17-11-14-5-3-2-4-6-14/h2-10H,11-12H2,1H3,(H2,17,18,19)
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n/an/a 1.00E+5n/an/an/an/a7.423



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
This assay is to identify inhibitors of the protein-protein interaction between the RUNX1 Runt domain and CBFbeta-SMMHC. This is accomplished by usin...


PubChem Bioassay (2009)


BindingDB Entry DOI: 10.7270/Q2T72FSX
More data for this
Ligand-Target Pair
Runt-Related Transcription Factor 1 Isoform AML1C


(Homo sapiens)
BDBM29697
PNG
(11-(4-Methoxy-phenyl)-2-pyridin-2-yl-11H-6-oxa-1,3...)
Show SMILES COc1ccc(cc1)C1c2ccc(O)cc2Oc2ncn3nc(nc3c12)-c1ccccn1
Show InChI InChI=1S/C24H17N5O3/c1-31-16-8-5-14(6-9-16)20-17-10-7-15(30)12-19(17)32-24-21(20)23-27-22(28-29(23)13-26-24)18-4-2-3-11-25-18/h2-13,20,30H,1H3
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n/an/a 1.00E+5n/an/an/an/a7.423



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
This assay is to identify inhibitors of the protein-protein interaction between the RUNX1 Runt domain and CBFbeta-SMMHC. This is accomplished by usin...


PubChem Bioassay (2009)


BindingDB Entry DOI: 10.7270/Q2T72FSX
More data for this
Ligand-Target Pair
Runt-Related Transcription Factor 1 Isoform AML1C


(Homo sapiens)
BDBM29698
PNG
(3, 6-Diacetamidoacridine | MLS000736567 | N-(6-ace...)
Show SMILES CC(=O)Nc1ccc2cc3ccc(NC(C)=O)cc3nc2c1
Show InChI InChI=1S/C17H15N3O2/c1-10(21)18-14-5-3-12-7-13-4-6-15(19-11(2)22)9-17(13)20-16(12)8-14/h3-9H,1-2H3,(H,18,21)(H,19,22)
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n/an/a 1.00E+5n/an/an/an/a7.423



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
This assay is to identify inhibitors of the protein-protein interaction between the RUNX1 Runt domain and CBFbeta-SMMHC. This is accomplished by usin...


PubChem Bioassay (2009)


BindingDB Entry DOI: 10.7270/Q2T72FSX
More data for this
Ligand-Target Pair
Runt-Related Transcription Factor 1 Isoform AML1C


(Homo sapiens)
BDBM29699
PNG
((3E)-1-methyl-3-(phenylazanylmethylidene)quinoline...)
Show SMILES Cn1c2ccccc2c(O)c(C=Nc2ccccc2)c1=O
Show InChI InChI=1S/C17H14N2O2/c1-19-15-10-6-5-9-13(15)16(20)14(17(19)21)11-18-12-7-3-2-4-8-12/h2-11,20H,1H3
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n/an/a 1.00E+5n/an/an/an/a7.423



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
This assay is to identify inhibitors of the protein-protein interaction between the RUNX1 Runt domain and CBFbeta-SMMHC. This is accomplished by usin...


PubChem Bioassay (2009)


BindingDB Entry DOI: 10.7270/Q2T72FSX
More data for this
Ligand-Target Pair
Runt-Related Transcription Factor 1 Isoform AML1C


(Homo sapiens)
BDBM26689
PNG
(2-keto-4-(4-pyridyl)-1,5-dihydrochromeno[4,3-b]pyr...)
Show SMILES O=c1[nH]c-2c(COc3ccccc-23)c(-c2ccncc2)c1C#N
Show InChI InChI=1S/C18H11N3O2/c19-9-13-16(11-5-7-20-8-6-11)14-10-23-15-4-2-1-3-12(15)17(14)21-18(13)22/h1-8H,10H2,(H,21,22)
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n/an/a 1.00E+5n/an/an/an/a7.423



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
This assay is to identify inhibitors of the protein-protein interaction between the RUNX1 Runt domain and CBFbeta-SMMHC. This is accomplished by usin...


PubChem Bioassay (2009)


BindingDB Entry DOI: 10.7270/Q2T72FSX
More data for this
Ligand-Target Pair
Runt-Related Transcription Factor 1 Isoform AML1C


(Homo sapiens)
BDBM29613
PNG
(2-Imino-1-(4-methyl-benzyl)-10-oxo-1,10-dihydro-2H...)
Show SMILES Cc1ccc(Cn2c3nc4ccccn4c(=O)c3cc(C(=O)NCc3ccco3)c2=N)cc1
Show InChI InChI=1S/C25H21N5O3/c1-16-7-9-17(10-8-16)15-30-22(26)19(24(31)27-14-18-5-4-12-33-18)13-20-23(30)28-21-6-2-3-11-29(21)25(20)32/h2-13,26H,14-15H2,1H3,(H,27,31)
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n/an/a 1.53E+4n/an/an/an/a7.423



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
This assay is to use HTS to identify inhibitors of the protein-protein interaction between the RUNX1 Runt domain and CBFbeta-SMMHC, a potential thera...


PubChem Bioassay (2009)


BindingDB Entry DOI: 10.7270/Q2DV1H7P
More data for this
Ligand-Target Pair
Runt-Related Transcription Factor 1 Isoform AML1C


(Homo sapiens)
BDBM29614
PNG
(6-methoxy-2-(1-pyrrolidinyl)-3-quinolinecarbonitri...)
Show SMILES COc1ccc2nc(N3CCCC3)c(cc2c1)C#N
Show InChI InChI=1S/C15H15N3O/c1-19-13-4-5-14-11(9-13)8-12(10-16)15(17-14)18-6-2-3-7-18/h4-5,8-9H,2-3,6-7H2,1H3
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n/an/a 1.00E+5n/an/an/an/a7.423



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
This assay is to use HTS to identify inhibitors of the protein-protein interaction between the RUNX1 Runt domain and CBFbeta-SMMHC, a potential thera...


PubChem Bioassay (2009)


BindingDB Entry DOI: 10.7270/Q2DV1H7P
More data for this
Ligand-Target Pair
Runt-Related Transcription Factor 1 Isoform AML1C


(Homo sapiens)
BDBM29615
PNG
(6-methoxy-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]qui...)
Show SMILES COc1cccc2C3C=CCC3C(Nc12)C(O)=O
Show InChI InChI=1S/C14H15NO3/c1-18-11-7-3-6-9-8-4-2-5-10(8)13(14(16)17)15-12(9)11/h2-4,6-8,10,13,15H,5H2,1H3,(H,16,17)
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n/an/a 1.54E+4n/an/an/an/a7.423



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
This assay is to use HTS to identify inhibitors of the protein-protein interaction between the RUNX1 Runt domain and CBFbeta-SMMHC, a potential thera...


PubChem Bioassay (2009)


BindingDB Entry DOI: 10.7270/Q2DV1H7P
More data for this
Ligand-Target Pair
Runt-Related Transcription Factor 1 Isoform AML1C


(Homo sapiens)
BDBM29616
PNG
(Dimethyl-[4-(2-methyl-5,6-dihydro-pyrazolo[1,5-c]q...)
Show SMILES CN(C)c1ccc(cc1)C1Nc2ccccc2-c2cc(C)nn12
Show InChI InChI=1S/C19H20N4/c1-13-12-18-16-6-4-5-7-17(16)20-19(23(18)21-13)14-8-10-15(11-9-14)22(2)3/h4-12,19-20H,1-3H3
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n/an/a 1.00E+5n/an/an/an/a7.423



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
This assay is to use HTS to identify inhibitors of the protein-protein interaction between the RUNX1 Runt domain and CBFbeta-SMMHC, a potential thera...


PubChem Bioassay (2009)


BindingDB Entry DOI: 10.7270/Q2DV1H7P
More data for this
Ligand-Target Pair
Runt-Related Transcription Factor 1 Isoform AML1C


(Homo sapiens)
BDBM29617
PNG
(2-azanylidene-1-(furan-2-ylmethyl)-3-(phenylsulfon...)
Show SMILES N=c1c(cc2c(nc3ccccn3c2=O)n1Cc1ccco1)S(=O)(=O)c1ccccc1
Show InChI InChI=1S/C22H16N4O4S/c23-20-18(31(28,29)16-8-2-1-3-9-16)13-17-21(26(20)14-15-7-6-12-30-15)24-19-10-4-5-11-25(19)22(17)27/h1-13,23H,14H2
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n/an/a 5.75E+4n/an/an/an/a7.423



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
This assay is to use HTS to identify inhibitors of the protein-protein interaction between the RUNX1 Runt domain and CBFbeta-SMMHC, a potential thera...


PubChem Bioassay (2009)


BindingDB Entry DOI: 10.7270/Q2DV1H7P
More data for this
Ligand-Target Pair
Runt-Related Transcription Factor 1 Isoform AML1C


(Homo sapiens)
BDBM29618
PNG
(3-(2-aminoethylamino)-7-(phenylmethyl)-1-[(phenylm...)
Show SMILES NCCNc1nc(NCc2ccccc2)c2CN(Cc3ccccc3)CCc2c1C#N
Show InChI InChI=1S/C25H28N6/c26-12-13-28-24-22(15-27)21-11-14-31(17-20-9-5-2-6-10-20)18-23(21)25(30-24)29-16-19-7-3-1-4-8-19/h1-10H,11-14,16-18,26H2,(H2,28,29,30)
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n/an/a 4.78E+4n/an/an/an/a7.423



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
This assay is to use HTS to identify inhibitors of the protein-protein interaction between the RUNX1 Runt domain and CBFbeta-SMMHC, a potential thera...


PubChem Bioassay (2009)


BindingDB Entry DOI: 10.7270/Q2DV1H7P
More data for this
Ligand-Target Pair
Runt-Related Transcription Factor 1 Isoform AML1C


(Homo sapiens)
BDBM29619
PNG
(6-ethyl-6-methyl-5,8-dihydro-1H-thiopyrano[2,3]thi...)
Show SMILES CCC1(C)Cc2c(CS1)sc1[nH]c(=O)[nH]c(=O)c21
Show InChI InChI=1S/C12H14N2O2S2/c1-3-12(2)4-6-7(5-17-12)18-10-8(6)9(15)13-11(16)14-10/h3-5H2,1-2H3,(H2,13,14,15,16)
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n/an/a 4.51E+4n/an/an/an/a7.423



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
This assay is to use HTS to identify inhibitors of the protein-protein interaction between the RUNX1 Runt domain and CBFbeta-SMMHC, a potential thera...


PubChem Bioassay (2009)


BindingDB Entry DOI: 10.7270/Q2DV1H7P
More data for this
Ligand-Target Pair
Runt-Related Transcription Factor 1 Isoform AML1C


(Homo sapiens)
BDBM29620
PNG
(2-amino-1-(2-furanylmethyl)-N-[2-(4-morpholinyl)et...)
Show SMILES Nc1c(C(=O)NCCN2CCOCC2)c2nc3ccccc3nc2n1Cc1ccco1
Show InChI InChI=1S/C22H24N6O3/c23-20-18(22(29)24-7-8-27-9-12-30-13-10-27)19-21(28(20)14-15-4-3-11-31-15)26-17-6-2-1-5-16(17)25-19/h1-6,11H,7-10,12-14,23H2,(H,24,29)
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n/an/a 1.00E+5n/an/an/an/a7.423



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
This assay is to use HTS to identify inhibitors of the protein-protein interaction between the RUNX1 Runt domain and CBFbeta-SMMHC, a potential thera...


PubChem Bioassay (2009)


BindingDB Entry DOI: 10.7270/Q2DV1H7P
More data for this
Ligand-Target Pair
Runt-Related Transcription Factor 1 Isoform AML1C


(Homo sapiens)
BDBM29621
PNG
(1-benzyl-2-(2-furoylamino)-N-(3-methoxypropyl)pyrr...)
Show SMILES COCCCNC(=O)c1c(NC(=O)c2ccco2)n(Cc2ccccc2)c2nc3ccccc3nc12
Show InChI InChI=1S/C27H25N5O4/c1-35-15-8-14-28-27(34)22-23-25(30-20-12-6-5-11-19(20)29-23)32(17-18-9-3-2-4-10-18)24(22)31-26(33)21-13-7-16-36-21/h2-7,9-13,16H,8,14-15,17H2,1H3,(H,28,34)(H,31,33)
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n/an/a 1.60E+4n/an/an/an/a7.423



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
This assay is to use HTS to identify inhibitors of the protein-protein interaction between the RUNX1 Runt domain and CBFbeta-SMMHC, a potential thera...


PubChem Bioassay (2009)


BindingDB Entry DOI: 10.7270/Q2DV1H7P
More data for this
Ligand-Target Pair
Runt-Related Transcription Factor 1 Isoform AML1C


(Homo sapiens)
BDBM29622
PNG
(MLS000078195 | SMR000041517 | cid_660761)
Show SMILES Cc1cc(C)cc(c1)-n1c2ncn(Cc3ccco3)c(=O)c2c2nc3ccccc3nc12
Show InChI InChI=1S/C25H19N5O2/c1-15-10-16(2)12-17(11-15)30-23-21(22-24(30)28-20-8-4-3-7-19(20)27-22)25(31)29(14-26-23)13-18-6-5-9-32-18/h3-12,14H,13H2,1-2H3
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n/an/a 3.40E+4n/an/an/an/a7.423



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
This assay is to use HTS to identify inhibitors of the protein-protein interaction between the RUNX1 Runt domain and CBFbeta-SMMHC, a potential thera...


PubChem Bioassay (2009)


BindingDB Entry DOI: 10.7270/Q2DV1H7P
More data for this
Ligand-Target Pair
Runt-Related Transcription Factor 1 Isoform AML1C


(Homo sapiens)
BDBM29626
PNG
(2-(2-furanyl)-3-(3-propan-2-yloxypropyl)imidazo[4,...)
Show SMILES CC(C)OCCCn1c(nc2nc3ccccc3nc12)-c1ccco1
Show InChI InChI=1S/C19H20N4O2/c1-13(2)24-12-6-10-23-18(16-9-5-11-25-16)22-17-19(23)21-15-8-4-3-7-14(15)20-17/h3-5,7-9,11,13H,6,10,12H2,1-2H3
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n/an/a 1.00E+5n/an/an/an/a7.423



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
This assay is to use HTS to identify inhibitors of the protein-protein interaction between the RUNX1 Runt domain and CBFbeta-SMMHC, a potential thera...


PubChem Bioassay (2009)


BindingDB Entry DOI: 10.7270/Q2DV1H7P
More data for this
Ligand-Target Pair
Runt-Related Transcription Factor 1 Isoform AML1C


(Homo sapiens)
BDBM29627
PNG
(2-azanylidene-N-[(4-fluorophenyl)methyl]-1-(furan-...)
Show SMILES Fc1ccc(CNC(=O)c2cc3c(nc4ccccn4c3=O)n(Cc3ccco3)c2=N)cc1
Show InChI InChI=1S/C24H18FN5O3/c25-16-8-6-15(7-9-16)13-27-23(31)18-12-19-22(28-20-5-1-2-10-29(20)24(19)32)30(21(18)26)14-17-4-3-11-33-17/h1-12,26H,13-14H2,(H,27,31)
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n/an/a 4.35E+4n/an/an/an/a7.423



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
This assay is to use HTS to identify inhibitors of the protein-protein interaction between the RUNX1 Runt domain and CBFbeta-SMMHC, a potential thera...


PubChem Bioassay (2009)


BindingDB Entry DOI: 10.7270/Q2DV1H7P
More data for this
Ligand-Target Pair
Runt-Related Transcription Factor 1 Isoform AML1C


(Homo sapiens)
BDBM29628
PNG
(MLS000042566 | SMR000047335 | cid_666073)
Show SMILES CN1CCc2c(C1)sc1c2c(NCc2ccco2)nc2nnnn12
Show InChI InChI=1S/C15H15N7OS/c1-21-5-4-10-11(8-21)24-14-12(10)13(16-7-9-3-2-6-23-9)17-15-18-19-20-22(14)15/h2-3,6H,4-5,7-8H2,1H3,(H,16,17,18,20)
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n/an/a 5.63E+4n/an/an/an/a7.423



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
This assay is to use HTS to identify inhibitors of the protein-protein interaction between the RUNX1 Runt domain and CBFbeta-SMMHC, a potential thera...


PubChem Bioassay (2009)


BindingDB Entry DOI: 10.7270/Q2DV1H7P
More data for this
Ligand-Target Pair
Runt-Related Transcription Factor 1 Isoform AML1C


(Homo sapiens)
BDBM29629
PNG
(1-(2-furanylmethyl)-3-(3-methylphenyl)sulfonyl-2-p...)
Show SMILES Cc1cccc(c1)S(=O)(=O)c1c(N)n(Cc2ccco2)c2nc3ccccc3nc12
Show InChI InChI=1S/C22H18N4O3S/c1-14-6-4-8-16(12-14)30(27,28)20-19-22(25-18-10-3-2-9-17(18)24-19)26(21(20)23)13-15-7-5-11-29-15/h2-12H,13,23H2,1H3
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n/an/a 1.00E+5n/an/an/an/a7.423



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
This assay is to use HTS to identify inhibitors of the protein-protein interaction between the RUNX1 Runt domain and CBFbeta-SMMHC, a potential thera...


PubChem Bioassay (2009)


BindingDB Entry DOI: 10.7270/Q2DV1H7P
More data for this
Ligand-Target Pair
Runt-Related Transcription Factor 1 Isoform AML1C


(Homo sapiens)
BDBM29630
PNG
(MLS000084335 | SMR000048147 | cid_666800)
Show SMILES CCc1ccc(cc1)C1C2=C(CC(C)(C)CC2=O)Nc2c1c(=O)nc1nc(C)[nH]n21
Show InChI InChI=1S/C23H25N5O2/c1-5-13-6-8-14(9-7-13)17-18-15(10-23(3,4)11-16(18)29)25-20-19(17)21(30)26-22-24-12(2)27-28(20)22/h6-9,17,25H,5,10-11H2,1-4H3,(H,24,26,27,30)
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n/an/a 3.12E+4n/an/an/an/a7.423



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
This assay is to use HTS to identify inhibitors of the protein-protein interaction between the RUNX1 Runt domain and CBFbeta-SMMHC, a potential thera...


PubChem Bioassay (2009)


BindingDB Entry DOI: 10.7270/Q2DV1H7P
More data for this
Ligand-Target Pair
Runt-Related Transcription Factor 1 Isoform AML1C


(Homo sapiens)
BDBM29631
PNG
(MLS000082179 | SMR000061522 | [3-amino-4-(1,3-benz...)
Show SMILES CCNc1sc(C(=O)c2cccs2)c(N)c1-c1nc2ccccc2s1
Show InChI InChI=1S/C18H15N3OS3/c1-2-20-17-13(18-21-10-6-3-4-7-11(10)24-18)14(19)16(25-17)15(22)12-8-5-9-23-12/h3-9,20H,2,19H2,1H3
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n/an/a 6.32E+4n/an/an/an/a7.423



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
This assay is to use HTS to identify inhibitors of the protein-protein interaction between the RUNX1 Runt domain and CBFbeta-SMMHC, a potential thera...


PubChem Bioassay (2009)


BindingDB Entry DOI: 10.7270/Q2DV1H7P
More data for this
Ligand-Target Pair
Runt-Related Transcription Factor 1 Isoform AML1C


(Homo sapiens)
BDBM29632
PNG
(2-[2-(3-keto-1,2-benzothiazol-2-yl)thiazol-4-yl]ac...)
Show SMILES CCOC(=O)Cc1csc(n1)-n1sc2ccccc2c1=O
Show InChI InChI=1S/C14H12N2O3S2/c1-2-19-12(17)7-9-8-20-14(15-9)16-13(18)10-5-3-4-6-11(10)21-16/h3-6,8H,2,7H2,1H3
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n/an/a 8.58E+3n/an/an/an/a7.423



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
This assay is to use HTS to identify inhibitors of the protein-protein interaction between the RUNX1 Runt domain and CBFbeta-SMMHC, a potential thera...


PubChem Bioassay (2009)


BindingDB Entry DOI: 10.7270/Q2DV1H7P
More data for this
Ligand-Target Pair
Runt-Related Transcription Factor 1 Isoform AML1C


(Homo sapiens)
BDBM29623
PNG
(1-(2-furanylmethyl)-2-imino-5-oxo-N-(phenylmethyl)...)
Show SMILES N=c1c(cc2c(nc3ccccn3c2=O)n1Cc1ccco1)C(=O)NCc1ccccc1
Show InChI InChI=1S/C24H19N5O3/c25-21-18(23(30)26-14-16-7-2-1-3-8-16)13-19-22(29(21)15-17-9-6-12-32-17)27-20-10-4-5-11-28(20)24(19)31/h1-13,25H,14-15H2,(H,26,30)
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n/an/a 3.66E+4n/an/an/an/a7.423



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
This assay is to use HTS to identify inhibitors of the protein-protein interaction between the RUNX1 Runt domain and CBFbeta-SMMHC, a potential thera...


PubChem Bioassay (2009)


BindingDB Entry DOI: 10.7270/Q2DV1H7P
More data for this
Ligand-Target Pair
Runt-Related Transcription Factor 1 Isoform AML1C


(Homo sapiens)
BDBM29624
PNG
(1-(2-furanylmethyl)-3-(4-methylphenyl)sulfonyl-2-p...)
Show SMILES Cc1ccc(cc1)S(=O)(=O)c1c(N)n(Cc2ccco2)c2nc3ccccc3nc12
Show InChI InChI=1S/C22H18N4O3S/c1-14-8-10-16(11-9-14)30(27,28)20-19-22(25-18-7-3-2-6-17(18)24-19)26(21(20)23)13-15-5-4-12-29-15/h2-12H,13,23H2,1H3
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n/an/a 1.00E+5n/an/an/an/a7.423



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
This assay is to use HTS to identify inhibitors of the protein-protein interaction between the RUNX1 Runt domain and CBFbeta-SMMHC, a potential thera...


PubChem Bioassay (2009)


BindingDB Entry DOI: 10.7270/Q2DV1H7P
More data for this
Ligand-Target Pair
Runt-Related Transcription Factor 1 Isoform AML1C


(Homo sapiens)
BDBM29625
PNG
(MLS000081576 | SMR000043748 | cid_662970)
Show SMILES Cc1cc(C)n2nc3nc4CCCCc4cc3c2n1
Show InChI InChI=1S/C15H16N4/c1-9-7-10(2)19-15(16-9)12-8-11-5-3-4-6-13(11)17-14(12)18-19/h7-8H,3-6H2,1-2H3
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n/an/a 1.00E+5n/an/an/an/a7.423



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
This assay is to use HTS to identify inhibitors of the protein-protein interaction between the RUNX1 Runt domain and CBFbeta-SMMHC, a potential thera...


PubChem Bioassay (2009)


BindingDB Entry DOI: 10.7270/Q2DV1H7P
More data for this
Ligand-Target Pair
Runt-Related Transcription Factor 1 Isoform AML1C


(Homo sapiens)
BDBM29633
PNG
(4-[(4-methyl-2,3-dihydro-1,4-benzothiazine-6-carbo...)
Show SMILES CCOC(=O)N1CCC(CC1)NC(=O)c1ccc2SCCN(C)c2c1
Show InChI InChI=1S/C18H25N3O3S/c1-3-24-18(23)21-8-6-14(7-9-21)19-17(22)13-4-5-16-15(12-13)20(2)10-11-25-16/h4-5,12,14H,3,6-11H2,1-2H3,(H,19,22)
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n/an/a 1.00E+5n/an/an/an/a7.423



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
This assay is to use HTS to identify inhibitors of the protein-protein interaction between the RUNX1 Runt domain and CBFbeta-SMMHC, a potential thera...


PubChem Bioassay (2009)


BindingDB Entry DOI: 10.7270/Q2DV1H7P
More data for this
Ligand-Target Pair
Runt-Related Transcription Factor 1 Isoform AML1C


(Homo sapiens)
BDBM29634
PNG
(1-(2-methyl-1H-perimidin-4-yl)ethanone | 1-(2-meth...)
Show SMILES CC(=O)c1ccc2cccc3nc(C)[nH]c1c23
Show InChI InChI=1S/C14H12N2O/c1-8(17)11-7-6-10-4-3-5-12-13(10)14(11)16-9(2)15-12/h3-7H,1-2H3,(H,15,16)
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n/an/a 1.00E+5n/an/an/an/a7.423



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
This assay is to use HTS to identify inhibitors of the protein-protein interaction between the RUNX1 Runt domain and CBFbeta-SMMHC, a potential thera...


PubChem Bioassay (2009)


BindingDB Entry DOI: 10.7270/Q2DV1H7P
More data for this
Ligand-Target Pair
Runt-Related Transcription Factor 1 Isoform AML1C


(Homo sapiens)
BDBM29635
PNG
(1-(2-furanylmethyl)-2-imino-3-(4-methylphenyl)sulf...)
Show SMILES Cc1ccc(cc1)S(=O)(=O)c1cc2c(nc3ccccn3c2=O)n(Cc2ccco2)c1=N
Show InChI InChI=1S/C23H18N4O4S/c1-15-7-9-17(10-8-15)32(29,30)19-13-18-22(25-20-6-2-3-11-26(20)23(18)28)27(21(19)24)14-16-5-4-12-31-16/h2-13,24H,14H2,1H3
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n/an/a 5.86E+4n/an/an/an/a7.423



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
This assay is to use HTS to identify inhibitors of the protein-protein interaction between the RUNX1 Runt domain and CBFbeta-SMMHC, a potential thera...


PubChem Bioassay (2009)


BindingDB Entry DOI: 10.7270/Q2DV1H7P
More data for this
Ligand-Target Pair
Runt-Related Transcription Factor 1 Isoform AML1C


(Homo sapiens)
BDBM29636
PNG
(2-spiro[1H-indole-3,2'-3H-1,3-benzothiazole]one | ...)
Show SMILES O=C1Nc2ccccc2C11Nc2ccccc2S1
Show InChI InChI=1S/C14H10N2OS/c17-13-14(9-5-1-2-6-10(9)15-13)16-11-7-3-4-8-12(11)18-14/h1-8,16H,(H,15,17)
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n/an/a 2.82E+4n/an/an/an/a7.423



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
This assay is to use HTS to identify inhibitors of the protein-protein interaction between the RUNX1 Runt domain and CBFbeta-SMMHC, a potential thera...


PubChem Bioassay (2009)


BindingDB Entry DOI: 10.7270/Q2DV1H7P
More data for this
Ligand-Target Pair
Runt-Related Transcription Factor 1 Isoform AML1C


(Homo sapiens)
BDBM29637
PNG
(1-(3-ethoxypropyl)-2-imino-10-methyl-5-oxo-1,5-dih...)
Show SMILES CCOCCCn1c2nc3c(C)cccn3c(=O)c2cc(C(N)=S)c1=N
Show InChI InChI=1S/C18H21N5O2S/c1-3-25-9-5-8-22-14(19)12(15(20)26)10-13-17(22)21-16-11(2)6-4-7-23(16)18(13)24/h4,6-7,10,19H,3,5,8-9H2,1-2H3,(H2,20,26)
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n/an/a 6.88E+4n/an/an/an/a7.423



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
This assay is to use HTS to identify inhibitors of the protein-protein interaction between the RUNX1 Runt domain and CBFbeta-SMMHC, a potential thera...


PubChem Bioassay (2009)


BindingDB Entry DOI: 10.7270/Q2DV1H7P
More data for this
Ligand-Target Pair
Runt-Related Transcription Factor 1 Isoform AML1C


(Homo sapiens)
BDBM29638
PNG
(1-[4-(2-furoyl)piperazino]-3-isopropyl-pyrido[1,2-...)
Show SMILES CC(C)c1cc(N2CCN(CC2)C(=O)c2ccco2)n2c3ccccc3nc2c1C#N
Show InChI InChI=1S/C24H23N5O2/c1-16(2)17-14-22(27-9-11-28(12-10-27)24(30)21-8-5-13-31-21)29-20-7-4-3-6-19(20)26-23(29)18(17)15-25/h3-8,13-14,16H,9-12H2,1-2H3
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n/an/a 1.00E+5n/an/an/an/a7.423



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
This assay is to use HTS to identify inhibitors of the protein-protein interaction between the RUNX1 Runt domain and CBFbeta-SMMHC, a potential thera...


PubChem Bioassay (2009)


BindingDB Entry DOI: 10.7270/Q2DV1H7P
More data for this
Ligand-Target Pair
Runt-Related Transcription Factor 1 Isoform AML1C


(Homo sapiens)
BDBM29639
PNG
((4E)-3-methyl-4-[[3-[(2-methyl-4-oxidanyl-phenyl)a...)
Show SMILES Cc1cc(O)ccc1Nc1nc2ccccc2nc1Nc1ccc(O)cc1C
Show InChI InChI=1S/C22H20N4O2/c1-13-11-15(27)7-9-17(13)23-21-22(24-18-10-8-16(28)12-14(18)2)26-20-6-4-3-5-19(20)25-21/h3-12,27-28H,1-2H3,(H,23,25)(H,24,26)
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n/an/a 7.08E+3n/an/an/an/a7.423



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
This assay is to use HTS to identify inhibitors of the protein-protein interaction between the RUNX1 Runt domain and CBFbeta-SMMHC, a potential thera...


PubChem Bioassay (2009)


BindingDB Entry DOI: 10.7270/Q2DV1H7P
More data for this
Ligand-Target Pair
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