BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 8 hits of ph data with Target = 'SUMO-1-specific protease'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
SUMO-1-specific protease


(Homo sapiens)
BDBM81510
PNG
(JCP-666)
Show SMILES OC(=O)CN(NC(=O)c1ccc(CNC(=O)c2cccc(c2)C(O)=O)cc1)C(=O)[C@H]1O[C@@H]1C(=O)N(Cc1cccc2ccccc12)Cc1cccc2ccccc12
Show InChI InChI=1S/C44H36N4O9/c49-37(50)26-48(46-41(52)30-20-18-27(19-21-30)23-45-40(51)31-12-7-13-32(22-31)44(55)56)43(54)39-38(57-39)42(53)47(24-33-14-5-10-28-8-1-3-16-35(28)33)25-34-15-6-11-29-9-2-4-17-36(29)34/h1-22,38-39H,23-26H2,(H,45,51)(H,46,52)(H,49,50)(H,55,56)/t38-,39-/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+5n/an/an/an/a8.037



Stanford University



Assay Description
The fluorogenic substrate library screen was performed with hSENP1 in low salt tris buffer at final concentration of 2uM. Fluorophore release (AFC) ...


Chem Biol 18: 722-32 (2011)


Article DOI: 10.1016/j.chembiol.2011.05.008
BindingDB Entry DOI: 10.7270/Q2542M2N
More data for this
Ligand-Target Pair
SUMO-1-specific protease


(Homo sapiens)
BDBM81511
PNG
(VEA-260)
Show SMILES OC(=O)c1cccc(c1)C(=O)NCc1ccc(cc1)C(=O)NNC(=O)[C@H]1O[C@@H]1C(=O)N(Cc1cccc2ccccc12)Cc1cccc2ccccc12
Show InChI InChI=1S/C42H34N4O7/c47-38(30-12-7-13-31(22-30)42(51)52)43-23-26-18-20-29(21-19-26)39(48)44-45-40(49)36-37(53-36)41(50)46(24-32-14-5-10-27-8-1-3-16-34(27)32)25-33-15-6-11-28-9-2-4-17-35(28)33/h1-22,36-37H,23-25H2,(H,43,47)(H,44,48)(H,45,49)(H,51,52)/t36-,37-/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+5n/an/an/an/a8.037



Stanford University



Assay Description
The fluorogenic substrate library screen was performed with hSENP1 in low salt tris buffer at final concentration of 2uM. Fluorophore release (AFC) ...


Chem Biol 18: 722-32 (2011)


Article DOI: 10.1016/j.chembiol.2011.05.008
BindingDB Entry DOI: 10.7270/Q2542M2N
More data for this
Ligand-Target Pair
SUMO-1-specific protease


(Homo sapiens)
BDBM81512
PNG
(VEA-417)
Show SMILES NC(=O)CNC(=O)c1ccc(cc1)C(=O)NNC(=O)[C@H]1O[C@@H]1C(=O)N(Cc1cccc2ccccc12)Cc1cccc2ccccc12
Show InChI InChI=1S/C36H31N5O6/c37-30(42)19-38-33(43)24-15-17-25(18-16-24)34(44)39-40-35(45)31-32(47-31)36(46)41(20-26-11-5-9-22-7-1-3-13-28(22)26)21-27-12-6-10-23-8-2-4-14-29(23)27/h1-18,31-32H,19-21H2,(H2,37,42)(H,38,43)(H,39,44)(H,40,45)/t31-,32-/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+5n/an/an/an/a8.037



Stanford University



Assay Description
The fluorogenic substrate library screen was performed with hSENP1 in low salt tris buffer at final concentration of 2uM. Fluorophore release (AFC) ...


Chem Biol 18: 722-32 (2011)


Article DOI: 10.1016/j.chembiol.2011.05.008
BindingDB Entry DOI: 10.7270/Q2542M2N
More data for this
Ligand-Target Pair
SUMO-1-specific protease


(Homo sapiens)
BDBM81517
PNG
(VEA-561)
Show SMILES CC(C)C[C@H](NC(=O)Cc1ccc(O)c(c1)N(=O)=O)C(=O)N[C@@H](CCCN=C(N)N)C(=O)NCC(=O)NCC(=O)COC(=O)c1c2ccccc2cc2ccccc12
Show InChI InChI=1S/C40H46N8O10/c1-23(2)16-31(46-34(51)18-24-13-14-33(50)32(17-24)48(56)57)38(54)47-30(12-7-15-43-40(41)42)37(53)45-21-35(52)44-20-27(49)22-58-39(55)36-28-10-5-3-8-25(28)19-26-9-4-6-11-29(26)36/h3-6,8-11,13-14,17,19,23,30-31,50H,7,12,15-16,18,20-22H2,1-2H3,(H,44,52)(H,45,53)(H,46,51)(H,47,54)(H4,41,42,43)/t30-,31-/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 4.20E+3n/an/an/an/a8.037



Stanford University



Assay Description
The fluorogenic substrate library screen was performed with hSENP1 in low salt tris buffer at final concentration of 2uM. Fluorophore release (AFC) ...


Chem Biol 18: 722-32 (2011)


Article DOI: 10.1016/j.chembiol.2011.05.008
BindingDB Entry DOI: 10.7270/Q2542M2N
More data for this
Ligand-Target Pair
SUMO-1-specific protease


(Homo sapiens)
BDBM81514
PNG
(VEA-401)
Show SMILES OC(=O)c1cccc(c1)C(=O)NCc1ccc(cc1)C(=O)NCC(=O)COC(=O)c1c2ccccc2cc2ccccc12
Show InChI InChI=1S/C34H26N2O7/c37-27(20-43-34(42)30-28-10-3-1-6-23(28)16-24-7-2-4-11-29(24)30)19-36-31(38)22-14-12-21(13-15-22)18-35-32(39)25-8-5-9-26(17-25)33(40)41/h1-17H,18-20H2,(H,35,39)(H,36,38)(H,40,41)
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a>4.00E+4n/an/an/an/a8.037



Stanford University



Assay Description
The fluorogenic substrate library screen was performed with hSENP1 in low salt tris buffer at final concentration of 2uM. Fluorophore release (AFC) ...


Chem Biol 18: 722-32 (2011)


Article DOI: 10.1016/j.chembiol.2011.05.008
BindingDB Entry DOI: 10.7270/Q2542M2N
More data for this
Ligand-Target Pair
SUMO-1-specific protease


(Homo sapiens)
BDBM81515
PNG
(VEA-499)
Show SMILES C[C@H](O)C(NC(=O)[C@H](CCC(N)=O)NC(=O)Cc1ccc(O)c(c1)N(=O)=O)C(=O)NCC(=O)NCC(=O)COC(=O)c1c2ccccc2cc2ccccc12
Show InChI InChI=1S/C37H38N6O12/c1-20(44)34(42-35(50)27(11-13-30(38)47)41-31(48)15-21-10-12-29(46)28(14-21)43(53)54)36(51)40-18-32(49)39-17-24(45)19-55-37(52)33-25-8-4-2-6-22(25)16-23-7-3-5-9-26(23)33/h2-10,12,14,16,20,27,34,44,46H,11,13,15,17-19H2,1H3,(H2,38,47)(H,39,49)(H,40,51)(H,41,48)(H,42,50)/t20-,27-,34?/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>6.00E+4n/an/an/an/a8.037



Stanford University



Assay Description
The fluorogenic substrate library screen was performed with hSENP1 in low salt tris buffer at final concentration of 2uM. Fluorophore release (AFC) ...


Chem Biol 18: 722-32 (2011)


Article DOI: 10.1016/j.chembiol.2011.05.008
BindingDB Entry DOI: 10.7270/Q2542M2N
More data for this
Ligand-Target Pair
SUMO-1-specific protease


(Homo sapiens)
BDBM81516
PNG
(VEA-500)
Show SMILES C[C@H](O)C(NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)Cc1ccc(O)c(c1)N(=O)=O)C(=O)NCC(=O)NCC(=O)COC(=O)c1c2ccccc2cc2ccccc12
Show InChI InChI=1S/C42H46N8O14/c1-22(51)38(41(60)46-20-36(57)45-19-26(52)21-64-42(61)37-27-8-4-2-6-24(27)18-25-7-3-5-9-28(25)37)49-40(59)30(12-15-34(44)55)48-39(58)29(11-14-33(43)54)47-35(56)17-23-10-13-32(53)31(16-23)50(62)63/h2-10,13,16,18,22,29-30,38,51,53H,11-12,14-15,17,19-21H2,1H3,(H2,43,54)(H2,44,55)(H,45,57)(H,46,60)(H,47,56)(H,48,58)(H,49,59)/t22-,29-,30-,38?/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>4.00E+4n/an/an/an/a8.037



Stanford University



Assay Description
The fluorogenic substrate library screen was performed with hSENP1 in low salt tris buffer at final concentration of 2uM. Fluorophore release (AFC) ...


Chem Biol 18: 722-32 (2011)


Article DOI: 10.1016/j.chembiol.2011.05.008
BindingDB Entry DOI: 10.7270/Q2542M2N
More data for this
Ligand-Target Pair
SUMO-1-specific protease


(Homo sapiens)
BDBM81513
PNG
(VEA-422)
Show SMILES NC(=O)[C@H](CC(O)=O)NC(=O)c1ccc(cc1)C(=O)NNC(=O)[C@H]1O[C@@H]1C(=O)N(Cc1cccc2ccccc12)Cc1cccc2ccccc12
Show InChI InChI=1S/C38H33N5O8/c39-34(46)30(19-31(44)45)40-35(47)24-15-17-25(18-16-24)36(48)41-42-37(49)32-33(51-32)38(50)43(20-26-11-5-9-22-7-1-3-13-28(22)26)21-27-12-6-10-23-8-2-4-14-29(23)27/h1-18,30,32-33H,19-21H2,(H2,39,46)(H,40,47)(H,41,48)(H,42,49)(H,44,45)/t30-,32-,33-/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+5n/an/an/an/a8.037



Stanford University



Assay Description
The fluorogenic substrate library screen was performed with hSENP1 in low salt tris buffer at final concentration of 2uM. Fluorophore release (AFC) ...


Chem Biol 18: 722-32 (2011)


Article DOI: 10.1016/j.chembiol.2011.05.008
BindingDB Entry DOI: 10.7270/Q2542M2N
More data for this
Ligand-Target Pair