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Compile Data Set for Download or QSAR

Found 31 hits of ph data with Target = 'Sarco/endoplasmic Reticulum Ca2+ ATPase 1'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Sarco/endoplasmic Reticulum Ca2+ ATPase 1


(Oryctolagus cuniculus)
BDBM34111
PNG
(BMC171353 Compound 6b | hydroquinone derivative, 2...)
Show SMILES Oc1ccc(O)c(Cc2ccccc2)c1
Show InChI InChI=1S/C13H12O2/c14-12-6-7-13(15)11(9-12)8-10-4-2-1-3-5-10/h1-7,9,14-15H,8H2
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PubMed
n/an/a 1.20E+5n/an/an/an/a7.337



Northern Kentucky University



Assay Description
Inhibitory potencies of compounds were determined in a coupled ATPase activity assay using SERCA microsomes at 14 different inhibitor concentrations....


Bioorg Med Chem 17: 6613-9 (2009)


Article DOI: 10.1016/j.bmc.2009.07.075
BindingDB Entry DOI: 10.7270/Q2154FCG
More data for this
Ligand-Target Pair
Sarco/endoplasmic Reticulum Ca2+ ATPase 1


(Oryctolagus cuniculus)
BDBM34140
PNG
(2,2,2-methanetriyltris(4-tert-butylphenol), 11)
Show SMILES CC(C)(C)c1ccc(O)c(c1)C(c1cc(ccc1O)C(C)(C)C)c1cc(ccc1O)C(C)(C)C
Show InChI InChI=1S/C31H40O3/c1-29(2,3)19-10-13-25(32)22(16-19)28(23-17-20(30(4,5)6)11-14-26(23)33)24-18-21(31(7,8)9)12-15-27(24)34/h10-18,28,32-34H,1-9H3
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PubMed
n/an/a 2.13E+4n/an/an/an/a7.337



Northern Kentucky University



Assay Description
Inhibitory potencies of compounds were determined in a coupled ATPase activity assay using SERCA microsomes at 14 different inhibitor concentrations....


Bioorg Med Chem 17: 1353-60 (2009)


Article DOI: 10.1016/j.bmc.2008.12.010
BindingDB Entry DOI: 10.7270/Q2WD3XX7
More data for this
Ligand-Target Pair
Sarco/endoplasmic Reticulum Ca2+ ATPase 1


(Oryctolagus cuniculus)
BDBM34113
PNG
(hydroquinone derivative, 2c)
Show SMILES COc1ccc(Cc2cc(O)ccc2O)cc1
Show InChI InChI=1S/C14H14O3/c1-17-13-5-2-10(3-6-13)8-11-9-12(15)4-7-14(11)16/h2-7,9,15-16H,8H2,1H3
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PubMed
n/an/a 7.30E+3n/an/an/an/a7.337



Northern Kentucky University



Assay Description
Inhibitory potencies of compounds were determined in a coupled ATPase activity assay using SERCA microsomes at 14 different inhibitor concentrations....


Bioorg Med Chem 17: 6613-9 (2009)


Article DOI: 10.1016/j.bmc.2009.07.075
BindingDB Entry DOI: 10.7270/Q2154FCG
More data for this
Ligand-Target Pair
Sarco/endoplasmic Reticulum Ca2+ ATPase 1


(Oryctolagus cuniculus)
BDBM34114
PNG
(hydroquinone derivative, 2d)
Show SMILES Oc1ccc(O)c(Cc2ccco2)c1
Show InChI InChI=1S/C11H10O3/c12-9-3-4-11(13)8(6-9)7-10-2-1-5-14-10/h1-6,12-13H,7H2
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n/an/a 5.20E+4n/an/an/an/a7.337



Northern Kentucky University



Assay Description
Inhibitory potencies of compounds were determined in a coupled ATPase activity assay using SERCA microsomes at 14 different inhibitor concentrations....


Bioorg Med Chem 17: 6613-9 (2009)


Article DOI: 10.1016/j.bmc.2009.07.075
BindingDB Entry DOI: 10.7270/Q2154FCG
More data for this
Ligand-Target Pair
Sarco/endoplasmic Reticulum Ca2+ ATPase 1


(Oryctolagus cuniculus)
BDBM34115
PNG
(hydroquinone derivative, 3a)
Show SMILES CCC(C)(C)c1cc(O)c(Cc2ccc(cc2)[N+]([O-])=O)cc1O
Show InChI InChI=1S/C18H21NO4/c1-4-18(2,3)15-11-16(20)13(10-17(15)21)9-12-5-7-14(8-6-12)19(22)23/h5-8,10-11,20-21H,4,9H2,1-3H3
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PubMed
n/an/a 3.80E+3n/an/an/an/a7.337



Northern Kentucky University



Assay Description
Inhibitory potencies of compounds were determined in a coupled ATPase activity assay using SERCA microsomes at 14 different inhibitor concentrations....


Bioorg Med Chem 17: 6613-9 (2009)


Article DOI: 10.1016/j.bmc.2009.07.075
BindingDB Entry DOI: 10.7270/Q2154FCG
More data for this
Ligand-Target Pair
Sarco/endoplasmic Reticulum Ca2+ ATPase 1


(Oryctolagus cuniculus)
BDBM34116
PNG
(hydroquinone derivative, 3b)
Show SMILES CCC(C)(CC)c1cc(O)c(Cc2ccc(cc2)[N+]([O-])=O)cc1O
Show InChI InChI=1S/C19H23NO4/c1-4-19(3,5-2)16-12-17(21)14(11-18(16)22)10-13-6-8-15(9-7-13)20(23)24/h6-9,11-12,21-22H,4-5,10H2,1-3H3
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n/an/a 1.20E+4n/an/an/an/a7.337



Northern Kentucky University



Assay Description
Inhibitory potencies of compounds were determined in a coupled ATPase activity assay using SERCA microsomes at 14 different inhibitor concentrations....


Bioorg Med Chem 17: 6613-9 (2009)


Article DOI: 10.1016/j.bmc.2009.07.075
BindingDB Entry DOI: 10.7270/Q2154FCG
More data for this
Ligand-Target Pair
Sarco/endoplasmic Reticulum Ca2+ ATPase 1


(Oryctolagus cuniculus)
BDBM34117
PNG
(hydroquinone derivative, 5a)
Show SMILES CCC(C)(C)c1cc(O)c(cc1O)C(C)(C)CC
Show InChI InChI=1S/C16H26O2/c1-7-15(3,4)11-9-14(18)12(10-13(11)17)16(5,6)8-2/h9-10,17-18H,7-8H2,1-6H3
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n/an/a 340n/an/an/an/a7.337



Northern Kentucky University



Assay Description
Inhibitory potencies of compounds were determined in a coupled ATPase activity assay using SERCA microsomes at 14 different inhibitor concentrations....


Bioorg Med Chem 17: 6613-9 (2009)


Article DOI: 10.1016/j.bmc.2009.07.075
BindingDB Entry DOI: 10.7270/Q2154FCG
More data for this
Ligand-Target Pair
Sarco/endoplasmic Reticulum Ca2+ ATPase 1


(Oryctolagus cuniculus)
BDBM34118
PNG
(hydroquinone derivative, 5b)
Show SMILES CCC(C)(CC)c1cc(O)c(cc1O)C(C)(CC)CC
Show InChI InChI=1S/C18H30O2/c1-7-17(5,8-2)13-11-16(20)14(12-15(13)19)18(6,9-3)10-4/h11-12,19-20H,7-10H2,1-6H3
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n/an/a 610n/an/an/an/a7.337



Northern Kentucky University



Assay Description
Inhibitory potencies of compounds were determined in a coupled ATPase activity assay using SERCA microsomes at 14 different inhibitor concentrations....


Bioorg Med Chem 17: 6613-9 (2009)


Article DOI: 10.1016/j.bmc.2009.07.075
BindingDB Entry DOI: 10.7270/Q2154FCG
More data for this
Ligand-Target Pair
Sarco/endoplasmic Reticulum Ca2+ ATPase 1


(Oryctolagus cuniculus)
BDBM34119
PNG
(hydroquinone derivative, 5c)
Show SMILES CCC(CC)(CC)c1cc(O)c(cc1O)C(CC)(CC)CC
Show InChI InChI=1S/C20H34O2/c1-7-19(8-2,9-3)15-13-18(22)16(14-17(15)21)20(10-4,11-5)12-6/h13-14,21-22H,7-12H2,1-6H3
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n/an/a 3.30E+3n/an/an/an/a7.337



Northern Kentucky University



Assay Description
Inhibitory potencies of compounds were determined in a coupled ATPase activity assay using SERCA microsomes at 14 different inhibitor concentrations....


Bioorg Med Chem 17: 6613-9 (2009)


Article DOI: 10.1016/j.bmc.2009.07.075
BindingDB Entry DOI: 10.7270/Q2154FCG
More data for this
Ligand-Target Pair
Sarco/endoplasmic Reticulum Ca2+ ATPase 1


(Oryctolagus cuniculus)
BDBM34120
PNG
(hydroquinone derivative, 6)
Show SMILES Oc1cc(CC=C)c(O)cc1CC=C
Show InChI InChI=1S/C12H14O2/c1-3-5-9-7-12(14)10(6-4-2)8-11(9)13/h3-4,7-8,13-14H,1-2,5-6H2
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n/an/a 6.00E+3n/an/an/an/a7.337



Northern Kentucky University



Assay Description
Inhibitory potencies of compounds were determined in a coupled ATPase activity assay using SERCA microsomes at 14 different inhibitor concentrations....


Bioorg Med Chem 17: 6613-9 (2009)


Article DOI: 10.1016/j.bmc.2009.07.075
BindingDB Entry DOI: 10.7270/Q2154FCG
More data for this
Ligand-Target Pair
Sarco/endoplasmic Reticulum Ca2+ ATPase 1


(Oryctolagus cuniculus)
BDBM34121
PNG
(hydroquinone derivative, 8b)
Show SMILES CC(C)(C)OC(=O)NCCCC(=O)Oc1cc(c(O)cc1C(C)(C)C)C(C)(C)C
Show InChI InChI=1S/C23H37NO5/c1-21(2,3)15-14-18(16(13-17(15)25)22(4,5)6)28-19(26)11-10-12-24-20(27)29-23(7,8)9/h13-14,25H,10-12H2,1-9H3,(H,24,27)
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n/an/a 2.90E+4n/an/an/an/a7.337



Northern Kentucky University



Assay Description
Inhibitory potencies of compounds were determined in a coupled ATPase activity assay using SERCA microsomes at 14 different inhibitor concentrations....


Bioorg Med Chem 17: 6613-9 (2009)


Article DOI: 10.1016/j.bmc.2009.07.075
BindingDB Entry DOI: 10.7270/Q2154FCG
More data for this
Ligand-Target Pair
Sarco/endoplasmic Reticulum Ca2+ ATPase 1


(Oryctolagus cuniculus)
BDBM34122
PNG
(hydroquinone derivative, 9)
Show SMILES CC(C)(C)c1cc(OC(=O)CCCN)c(cc1O)C(C)(C)C
Show InChI InChI=1S/C18H29NO3/c1-17(2,3)12-11-15(22-16(21)8-7-9-19)13(10-14(12)20)18(4,5)6/h10-11,20H,7-9,19H2,1-6H3
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n/an/a 2.60E+3n/an/an/an/a7.337



Northern Kentucky University



Assay Description
Inhibitory potencies of compounds were determined in a coupled ATPase activity assay using SERCA microsomes at 14 different inhibitor concentrations....


Bioorg Med Chem 17: 6613-9 (2009)


Article DOI: 10.1016/j.bmc.2009.07.075
BindingDB Entry DOI: 10.7270/Q2154FCG
More data for this
Ligand-Target Pair
Sarco/endoplasmic Reticulum Ca2+ ATPase 1


(Oryctolagus cuniculus)
BDBM34123
PNG
(phenol derivative, 1a)
Show SMILES CC(C)Cc1ccc(CC(C)C)c(O)c1
Show InChI InChI=1S/C14H22O/c1-10(2)7-12-5-6-13(8-11(3)4)14(15)9-12/h5-6,9-11,15H,7-8H2,1-4H3
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n/an/a 1.88E+4n/an/an/an/a7.337



Northern Kentucky University



Assay Description
Inhibitory potencies of compounds were determined in a coupled ATPase activity assay using SERCA microsomes at 14 different inhibitor concentrations....


Bioorg Med Chem 17: 1353-60 (2009)


Article DOI: 10.1016/j.bmc.2008.12.010
BindingDB Entry DOI: 10.7270/Q2WD3XX7
More data for this
Ligand-Target Pair
Sarco/endoplasmic Reticulum Ca2+ ATPase 1


(Oryctolagus cuniculus)
BDBM34124
PNG
(hydroquinone derivative, 1b)
Show SMILES Oc1ccc(O)c(c1)C1CCCCCCC1
Show InChI InChI=1S/C14H20O2/c15-12-8-9-14(16)13(10-12)11-6-4-2-1-3-5-7-11/h8-11,15-16H,1-7H2
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n/an/a 1.15E+4n/an/an/an/a7.337



Northern Kentucky University



Assay Description
Inhibitory potencies of compounds were determined in a coupled ATPase activity assay using SERCA microsomes at 14 different inhibitor concentrations....


Bioorg Med Chem 17: 1353-60 (2009)


Article DOI: 10.1016/j.bmc.2008.12.010
BindingDB Entry DOI: 10.7270/Q2WD3XX7
More data for this
Ligand-Target Pair
Sarco/endoplasmic Reticulum Ca2+ ATPase 1


(Oryctolagus cuniculus)
BDBM34125
PNG
(2-Phenylhydroquinone, 7 | hydroquinone derivative,...)
Show SMILES Oc1ccc(O)c(c1)-c1ccccc1
Show InChI InChI=1S/C12H10O2/c13-10-6-7-12(14)11(8-10)9-4-2-1-3-5-9/h1-8,13-14H
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n/an/a 2.29E+3n/an/an/an/a7.337



Northern Kentucky University



Assay Description
Inhibitory potencies of compounds were determined in a coupled ATPase activity assay using SERCA microsomes at 14 different inhibitor concentrations....


Bioorg Med Chem 17: 1353-60 (2009)


Article DOI: 10.1016/j.bmc.2008.12.010
BindingDB Entry DOI: 10.7270/Q2WD3XX7
More data for this
Ligand-Target Pair
Sarco/endoplasmic Reticulum Ca2+ ATPase 1


(Oryctolagus cuniculus)
BDBM34126
PNG
(US9688816, 1 | bis(2,6-dimethylphenol), 2)
Show SMILES Cc1cc(cc(C)c1O)C(C)(C)c1cc(C)c(O)c(C)c1
Show InChI InChI=1S/C19H24O2/c1-11-7-15(8-12(2)17(11)20)19(5,6)16-9-13(3)18(21)14(4)10-16/h7-10,20-21H,1-6H3
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n/an/a 1.95E+4n/an/an/an/a7.337



Northern Kentucky University



Assay Description
Inhibitory potencies of compounds were determined in a coupled ATPase activity assay using SERCA microsomes at 14 different inhibitor concentrations....


Bioorg Med Chem 17: 1353-60 (2009)


Article DOI: 10.1016/j.bmc.2008.12.010
BindingDB Entry DOI: 10.7270/Q2WD3XX7
More data for this
Ligand-Target Pair
Sarco/endoplasmic Reticulum Ca2+ ATPase 1


(Oryctolagus cuniculus)
BDBM34127
PNG
(6-tert-butyl-2,3-dihydro-1H-inden-5-ol, 3)
Show SMILES CC(C)(C)c1cc2CCCc2cc1O
Show InChI InChI=1S/C13H18O/c1-13(2,3)11-7-9-5-4-6-10(9)8-12(11)14/h7-8,14H,4-6H2,1-3H3
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n/an/a 2.81E+4n/an/an/an/a7.337



Northern Kentucky University



Assay Description
Inhibitory potencies of compounds were determined in a coupled ATPase activity assay using SERCA microsomes at 14 different inhibitor concentrations....


Bioorg Med Chem 17: 1353-60 (2009)


Article DOI: 10.1016/j.bmc.2008.12.010
BindingDB Entry DOI: 10.7270/Q2WD3XX7
More data for this
Ligand-Target Pair
Sarco/endoplasmic Reticulum Ca2+ ATPase 1


(Oryctolagus cuniculus)
BDBM34128
PNG
(2,4-di-tert-butyl-6-(1-phenylethyl)phenol, 4a)
Show SMILES CC(c1ccccc1)c1cc(cc(c1O)C(C)(C)C)C(C)(C)C
Show InChI InChI=1S/C22H30O/c1-15(16-11-9-8-10-12-16)18-13-17(21(2,3)4)14-19(20(18)23)22(5,6)7/h8-15,23H,1-7H3
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n/an/a 3.38E+4n/an/an/an/a7.337



Northern Kentucky University



Assay Description
Inhibitory potencies of compounds were determined in a coupled ATPase activity assay using SERCA microsomes at 14 different inhibitor concentrations....


Bioorg Med Chem 17: 1353-60 (2009)


Article DOI: 10.1016/j.bmc.2008.12.010
BindingDB Entry DOI: 10.7270/Q2WD3XX7
More data for this
Ligand-Target Pair
Sarco/endoplasmic Reticulum Ca2+ ATPase 1


(Oryctolagus cuniculus)
BDBM34129
PNG
(2,4-di-tert-butyl-6-[1-(4-methoxyphenyl)ethyl]phen...)
Show SMILES COc1ccc(cc1)C(C)c1cc(cc(c1O)C(C)(C)C)C(C)(C)C
Show InChI InChI=1S/C23H32O2/c1-15(16-9-11-18(25-8)12-10-16)19-13-17(22(2,3)4)14-20(21(19)24)23(5,6)7/h9-15,24H,1-8H3
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n/an/a 3.53E+4n/an/an/an/a7.337



Northern Kentucky University



Assay Description
Inhibitory potencies of compounds were determined in a coupled ATPase activity assay using SERCA microsomes at 14 different inhibitor concentrations....


Bioorg Med Chem 17: 1353-60 (2009)


Article DOI: 10.1016/j.bmc.2008.12.010
BindingDB Entry DOI: 10.7270/Q2WD3XX7
More data for this
Ligand-Target Pair
Sarco/endoplasmic Reticulum Ca2+ ATPase 1


(Oryctolagus cuniculus)
BDBM34130
PNG
(2,6-di-tert-butyl-4-[1-(4-methoxyphenyl)ethyl]phen...)
Show SMILES COc1ccc(cc1)C(C)c1cc(c(O)c(c1)C(C)(C)C)C(C)(C)C
Show InChI InChI=1S/C23H32O2/c1-15(16-9-11-18(25-8)12-10-16)17-13-19(22(2,3)4)21(24)20(14-17)23(5,6)7/h9-15,24H,1-8H3
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n/an/a 4.54E+4n/an/an/an/a7.337



Northern Kentucky University



Assay Description
Inhibitory potencies of compounds were determined in a coupled ATPase activity assay using SERCA microsomes at 14 different inhibitor concentrations....


Bioorg Med Chem 17: 1353-60 (2009)


Article DOI: 10.1016/j.bmc.2008.12.010
BindingDB Entry DOI: 10.7270/Q2WD3XX7
More data for this
Ligand-Target Pair
Sarco/endoplasmic Reticulum Ca2+ ATPase 1


(Oryctolagus cuniculus)
BDBM34131
PNG
(2,2-methanediylbis(4-tert-butylphenol), 5a)
Show SMILES CC(C)(C)c1ccc(O)c(Cc2cc(ccc2O)C(C)(C)C)c1
Show InChI InChI=1S/C21H28O2/c1-20(2,3)16-7-9-18(22)14(12-16)11-15-13-17(21(4,5)6)8-10-19(15)23/h7-10,12-13,22-23H,11H2,1-6H3
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PubMed
n/an/a 1.18E+4n/an/an/an/a7.337



Northern Kentucky University



Assay Description
Inhibitory potencies of compounds were determined in a coupled ATPase activity assay using SERCA microsomes at 14 different inhibitor concentrations....


Bioorg Med Chem 17: 1353-60 (2009)


Article DOI: 10.1016/j.bmc.2008.12.010
BindingDB Entry DOI: 10.7270/Q2WD3XX7
More data for this
Ligand-Target Pair
Sarco/endoplasmic Reticulum Ca2+ ATPase 1


(Oryctolagus cuniculus)
BDBM34132
PNG
(4-(1,1-diphenylethyl)phenol, 5b)
Show SMILES CC(c1ccccc1)(c1ccccc1)c1ccc(O)cc1
Show InChI InChI=1S/C20H18O/c1-20(16-8-4-2-5-9-16,17-10-6-3-7-11-17)18-12-14-19(21)15-13-18/h2-15,21H,1H3
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n/an/a 4.97E+4n/an/an/an/a7.337



Northern Kentucky University



Assay Description
Inhibitory potencies of compounds were determined in a coupled ATPase activity assay using SERCA microsomes at 14 different inhibitor concentrations....


Bioorg Med Chem 17: 1353-60 (2009)


Article DOI: 10.1016/j.bmc.2008.12.010
BindingDB Entry DOI: 10.7270/Q2WD3XX7
More data for this
Ligand-Target Pair
Sarco/endoplasmic Reticulum Ca2+ ATPase 1


(Oryctolagus cuniculus)
BDBM34133
PNG
(4,4-butane-2,2-diylbis(2-methylphenol), 5c)
Show SMILES CCC(C)(c1ccc(O)c(C)c1)c1ccc(O)c(C)c1
Show InChI InChI=1S/C18H22O2/c1-5-18(4,14-6-8-16(19)12(2)10-14)15-7-9-17(20)13(3)11-15/h6-11,19-20H,5H2,1-4H3
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n/an/a 3.93E+4n/an/an/an/a7.337



Northern Kentucky University



Assay Description
Inhibitory potencies of compounds were determined in a coupled ATPase activity assay using SERCA microsomes at 14 different inhibitor concentrations....


Bioorg Med Chem 17: 1353-60 (2009)


Article DOI: 10.1016/j.bmc.2008.12.010
BindingDB Entry DOI: 10.7270/Q2WD3XX7
More data for this
Ligand-Target Pair
Sarco/endoplasmic Reticulum Ca2+ ATPase 1


(Oryctolagus cuniculus)
BDBM34134
PNG
(2,5-dibenzylbenzene-1,4-diol, 6a)
Show SMILES Oc1cc(Cc2ccccc2)c(O)cc1Cc1ccccc1
Show InChI InChI=1S/C20H18O2/c21-19-14-18(12-16-9-5-2-6-10-16)20(22)13-17(19)11-15-7-3-1-4-8-15/h1-10,13-14,21-22H,11-12H2
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n/an/a 9.40E+3n/an/an/an/a7.337



Northern Kentucky University



Assay Description
Inhibitory potencies of compounds were determined in a coupled ATPase activity assay using SERCA microsomes at 14 different inhibitor concentrations....


Bioorg Med Chem 17: 1353-60 (2009)


Article DOI: 10.1016/j.bmc.2008.12.010
BindingDB Entry DOI: 10.7270/Q2WD3XX7
More data for this
Ligand-Target Pair
Sarco/endoplasmic Reticulum Ca2+ ATPase 1


(Oryctolagus cuniculus)
BDBM34111
PNG
(BMC171353 Compound 6b | hydroquinone derivative, 2...)
Show SMILES Oc1ccc(O)c(Cc2ccccc2)c1
Show InChI InChI=1S/C13H12O2/c14-12-6-7-13(15)11(9-12)8-10-4-2-1-3-5-10/h1-7,9,14-15H,8H2
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n/an/a 2.02E+4n/an/an/an/a7.337



Northern Kentucky University



Assay Description
Inhibitory potencies of compounds were determined in a coupled ATPase activity assay using SERCA microsomes at 14 different inhibitor concentrations....


Bioorg Med Chem 17: 1353-60 (2009)


Article DOI: 10.1016/j.bmc.2008.12.010
BindingDB Entry DOI: 10.7270/Q2WD3XX7
More data for this
Ligand-Target Pair
Sarco/endoplasmic Reticulum Ca2+ ATPase 1


(Oryctolagus cuniculus)
BDBM34135
PNG
(1-(naphthalen-1-ylmethyl)naphthalen-2-ol, 7a)
Show SMILES Oc1ccc2ccccc2c1Cc1cccc2ccccc12
Show InChI InChI=1S/C21H16O/c22-21-13-12-16-7-2-4-11-19(16)20(21)14-17-9-5-8-15-6-1-3-10-18(15)17/h1-13,22H,14H2
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n/an/a 2.73E+4n/an/an/an/a7.337



Northern Kentucky University



Assay Description
Inhibitory potencies of compounds were determined in a coupled ATPase activity assay using SERCA microsomes at 14 different inhibitor concentrations....


Bioorg Med Chem 17: 1353-60 (2009)


Article DOI: 10.1016/j.bmc.2008.12.010
BindingDB Entry DOI: 10.7270/Q2WD3XX7
More data for this
Ligand-Target Pair
Sarco/endoplasmic Reticulum Ca2+ ATPase 1


(Oryctolagus cuniculus)
BDBM34136
PNG
(1,1-methanediyldinaphthalen-2-ol, 7b)
Show SMILES Oc1ccc2ccccc2c1Cc1c(O)ccc2ccccc12
Show InChI InChI=1S/C21H16O2/c22-20-11-9-14-5-1-3-7-16(14)18(20)13-19-17-8-4-2-6-15(17)10-12-21(19)23/h1-12,22-23H,13H2
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n/an/a 1.50E+4n/an/an/an/a7.337



Northern Kentucky University



Assay Description
Inhibitory potencies of compounds were determined in a coupled ATPase activity assay using SERCA microsomes at 14 different inhibitor concentrations....


Bioorg Med Chem 17: 1353-60 (2009)


Article DOI: 10.1016/j.bmc.2008.12.010
BindingDB Entry DOI: 10.7270/Q2WD3XX7
More data for this
Ligand-Target Pair
Sarco/endoplasmic Reticulum Ca2+ ATPase 1


(Oryctolagus cuniculus)
BDBM34137
PNG
(4,4-butane-2,3-diyldiphenol, 8)
Show SMILES CC(C(C)c1ccc(O)cc1)c1ccc(O)cc1
Show InChI InChI=1S/C16H18O2/c1-11(13-3-7-15(17)8-4-13)12(2)14-5-9-16(18)10-6-14/h3-12,17-18H,1-2H3
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n/an/a 2.83E+4n/an/an/an/a7.337



Northern Kentucky University



Assay Description
Inhibitory potencies of compounds were determined in a coupled ATPase activity assay using SERCA microsomes at 14 different inhibitor concentrations....


Bioorg Med Chem 17: 1353-60 (2009)


Article DOI: 10.1016/j.bmc.2008.12.010
BindingDB Entry DOI: 10.7270/Q2WD3XX7
More data for this
Ligand-Target Pair
Sarco/endoplasmic Reticulum Ca2+ ATPase 1


(Oryctolagus cuniculus)
BDBM34138
PNG
(4,5-dibenzylbenzene-1,2-diol, 9)
Show SMILES Oc1cc(Cc2ccccc2)c(Cc2ccccc2)cc1O
Show InChI InChI=1S/C20H18O2/c21-19-13-17(11-15-7-3-1-4-8-15)18(14-20(19)22)12-16-9-5-2-6-10-16/h1-10,13-14,21-22H,11-12H2
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n/an/a 2.38E+4n/an/an/an/a7.337



Northern Kentucky University



Assay Description
Inhibitory potencies of compounds were determined in a coupled ATPase activity assay using SERCA microsomes at 14 different inhibitor concentrations....


Bioorg Med Chem 17: 1353-60 (2009)


Article DOI: 10.1016/j.bmc.2008.12.010
BindingDB Entry DOI: 10.7270/Q2WD3XX7
More data for this
Ligand-Target Pair
Sarco/endoplasmic Reticulum Ca2+ ATPase 1


(Oryctolagus cuniculus)
BDBM34139
PNG
(4-(7-methyloctyl)phenol, 10)
Show SMILES CC(C)CCCCCCc1ccc(O)cc1
Show InChI InChI=1S/C15H24O/c1-13(2)7-5-3-4-6-8-14-9-11-15(16)12-10-14/h9-13,16H,3-8H2,1-2H3
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n/an/a 1.72E+4n/an/an/an/a7.337



Northern Kentucky University



Assay Description
Inhibitory potencies of compounds were determined in a coupled ATPase activity assay using SERCA microsomes at 14 different inhibitor concentrations....


Bioorg Med Chem 17: 1353-60 (2009)


Article DOI: 10.1016/j.bmc.2008.12.010
BindingDB Entry DOI: 10.7270/Q2WD3XX7
More data for this
Ligand-Target Pair
Sarco/endoplasmic Reticulum Ca2+ ATPase 1


(Oryctolagus cuniculus)
BDBM34112
PNG
(hydroquinone derivative, 2b)
Show SMILES Oc1ccc(O)c(Cc2ccc(cc2)[N+]([O-])=O)c1
Show InChI InChI=1S/C13H11NO4/c15-12-5-6-13(16)10(8-12)7-9-1-3-11(4-2-9)14(17)18/h1-6,8,15-16H,7H2
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n/an/a 5.70E+3n/an/an/an/a7.337



Northern Kentucky University



Assay Description
Inhibitory potencies of compounds were determined in a coupled ATPase activity assay using SERCA microsomes at 14 different inhibitor concentrations....


Bioorg Med Chem 17: 6613-9 (2009)


Article DOI: 10.1016/j.bmc.2009.07.075
BindingDB Entry DOI: 10.7270/Q2154FCG
More data for this
Ligand-Target Pair