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Compile Data Set for Download or QSAR

Found 6 hits of ph data with Target = 'Trans-sialidase'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Trans-sialidase


(Trypanosoma cruzi)
BDBM84698
PNG
(Quinolinone derivative, 9)
Show SMILES Cc1ccc(cc1)S(=O)(=O)N1C(\C(=C/c2ccc(O)c(O)c2)C(=O)c2ccccc12)c1ccc(O)c(O)c1
Show InChI InChI=1S/C29H23NO7S/c1-17-6-10-20(11-7-17)38(36,37)30-23-5-3-2-4-21(23)29(35)22(14-18-8-12-24(31)26(33)15-18)28(30)19-9-13-25(32)27(34)16-19/h2-16,28,31-34H,1H3/b22-14+
PDB

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
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PC cid
PC sid
UniChem

Similars

Article
PubMed
400 -37.7 600n/an/an/an/a7.635



University of British Columbia



Assay Description
Inhibition assay using trans-sialidase, a membrane-associated protein.


Chembiochem 10: 2475-9 (2009)


Article DOI: 10.1002/cbic.200900108
BindingDB Entry DOI: 10.7270/Q2MG7N10
More data for this
Ligand-Target Pair
Trans-sialidase


(Trypanosoma cruzi)
BDBM50174833
PNG
(CHEMBL199442 | N-(3-(3-(3,4-dihydroxyphenyl)acrylo...)
Show SMILES Cc1ccc(cc1)S(=O)(=O)Nc1cccc(c1)C(=O)\C=C\c1ccc(O)c(O)c1
Show InChI InChI=1S/C22H19NO5S/c1-15-5-9-19(10-6-15)29(27,28)23-18-4-2-3-17(14-18)20(24)11-7-16-8-12-21(25)22(26)13-16/h2-14,23,25-26H,1H3/b11-7+
PDB

UniProtKB/TrEMBL

B.MOAD
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CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
3.70E+3 -32.0 2.50E+3n/an/an/an/a7.635



University of British Columbia



Assay Description
Inhibition assay using trans-sialidase, a membrane-associated protein.


Chembiochem 10: 2475-9 (2009)


Article DOI: 10.1002/cbic.200900108
BindingDB Entry DOI: 10.7270/Q2MG7N10
More data for this
Ligand-Target Pair
Trans-sialidase


(Trypanosoma cruzi)
BDBM50174837
PNG
(4'-(p-toluenesulfonamide)-3,4-dihydroxy chalcone |...)
Show SMILES Cc1ccc(cc1)S(=O)(=O)Nc1ccc(cc1)C(=O)\C=C\c1ccc(O)c(O)c1
Show InChI InChI=1S/C22H19NO5S/c1-15-2-10-19(11-3-15)29(27,28)23-18-8-6-17(7-9-18)20(24)12-4-16-5-13-21(25)22(26)14-16/h2-14,23,25-26H,1H3/b12-4+
PDB

UniProtKB/TrEMBL

B.MOAD
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CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
4.60E+3 -31.5 900n/an/an/an/a7.635



University of British Columbia



Assay Description
Inhibition assay using trans-sialidase, a membrane-associated protein.


Chembiochem 10: 2475-9 (2009)


Article DOI: 10.1002/cbic.200900108
BindingDB Entry DOI: 10.7270/Q2MG7N10
More data for this
Ligand-Target Pair
Trans-sialidase


(Trypanosoma cruzi)
BDBM84697
PNG
(Quinolinone derivative, 8)
Show SMILES Cc1ccc(cc1)S(=O)(=O)N1C(\C(=C/c2ccc(O)cc2)C(=O)c2ccccc12)c1ccc(O)cc1
Show InChI InChI=1S/C29H23NO5S/c1-19-6-16-24(17-7-19)36(34,35)30-27-5-3-2-4-25(27)29(33)26(18-20-8-12-22(31)13-9-20)28(30)21-10-14-23(32)15-11-21/h2-18,28,31-32H,1H3/b26-18+
PDB

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 3.00E+4n/an/an/an/a7.635



University of British Columbia



Assay Description
Inhibition assay using trans-sialidase, a membrane-associated protein.


Chembiochem 10: 2475-9 (2009)


Article DOI: 10.1002/cbic.200900108
BindingDB Entry DOI: 10.7270/Q2MG7N10
More data for this
Ligand-Target Pair
Trans-sialidase


(Trypanosoma cruzi)
BDBM50174835
PNG
(4'-(4-toluenesulfonamido)-4-hydroxychalcone | 4'-(...)
Show SMILES Cc1ccc(cc1)S(=O)(=O)Nc1ccc(cc1)C(=O)\C=C\c1ccc(O)cc1
Show InChI InChI=1S/C22H19NO4S/c1-16-2-13-21(14-3-16)28(26,27)23-19-9-7-18(8-10-19)22(25)15-6-17-4-11-20(24)12-5-17/h2-15,23-24H,1H3/b15-6+
PDB

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 7.30E+4n/an/an/an/a7.635



University of British Columbia



Assay Description
Inhibition assay using trans-sialidase, a membrane-associated protein.


Chembiochem 10: 2475-9 (2009)


Article DOI: 10.1002/cbic.200900108
BindingDB Entry DOI: 10.7270/Q2MG7N10
More data for this
Ligand-Target Pair
Trans-sialidase


(Trypanosoma cruzi)
BDBM50174834
PNG
(CHEMBL382280 | N-(3-(3-(4-hydroxyphenyl)acryloyl)p...)
Show SMILES Cc1ccc(cc1)S(=O)(=O)Nc1cccc(c1)C(=O)\C=C\c1ccc(O)cc1
Show InChI InChI=1S/C22H19NO4S/c1-16-5-12-21(13-6-16)28(26,27)23-19-4-2-3-18(15-19)22(25)14-9-17-7-10-20(24)11-8-17/h2-15,23-24H,1H3/b14-9+
PDB

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 3.70E+4n/an/an/an/a7.635



University of British Columbia



Assay Description
Inhibition assay using trans-sialidase, a membrane-associated protein.


Chembiochem 10: 2475-9 (2009)


Article DOI: 10.1002/cbic.200900108
BindingDB Entry DOI: 10.7270/Q2MG7N10
More data for this
Ligand-Target Pair