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Found 463 hits of ph data with Target = 'Tyrosine-protein kinase JAK1'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Tyrosine-protein kinase JAK1


(Homo sapiens (Human))
BDBM81442
PNG
(CP-690,550)
Show SMILES C[C@@H]1CCC(CC1N(C)c1ncnc2[nH]ccc12)C(=O)CC#N
Show InChI InChI=1S/C17H21N5O/c1-11-3-4-12(15(23)5-7-18)9-14(11)22(2)17-13-6-8-19-16(13)20-10-21-17/h6,8,10-12,14H,3-5,9H2,1-2H3,(H,19,20,21)/t11-,12?,14?/m1/s1
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PubMed
n/an/a 6.10n/an/an/an/a7.530



University of Luxembourg



Assay Description
Enzyme assay affinity-purified GST fusions of the active kinase domains (GST-Jak1(866-1154), GST-Jak2(808-1132), GST-Jak3(811-1124) and GST-Tyk2(888-...


Chem Biol 18: 314-23 (2011)


Article DOI: 10.1016/j.chembiol.2011.01.012
BindingDB Entry DOI: 10.7270/Q2736PDR
More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK1


(Homo sapiens (Human))
BDBM26198
PNG
(4-tert-butyl-15-fluoro-3,5,10-triazatetracyclo[11....)
Show SMILES CC(C)(C)c1nc2c([nH]1)c1ccc(F)cc1c1c2cc[nH]c1=O
Show InChI InChI=1S/C18H16FN3O/c1-18(2,3)17-21-14-10-5-4-9(19)8-12(10)13-11(15(14)22-17)6-7-20-16(13)23/h4-8H,1-3H3,(H,20,23)(H,21,22)
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Article
PubMed
n/an/a 5.20n/an/an/an/a7.530



University of Luxembourg



Assay Description
Enzyme assay affinity-purified GST fusions of the active kinase domains (GST-Jak1(866-1154), GST-Jak2(808-1132), GST-Jak3(811-1124) and GST-Tyk2(888-...


Chem Biol 18: 314-23 (2011)


Article DOI: 10.1016/j.chembiol.2011.01.012
BindingDB Entry DOI: 10.7270/Q2736PDR
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Tyrosine-protein kinase JAK1


(Homo sapiens (Human))
BDBM50335231
PNG
(3-{5-[4-(2-Hydroxy-2-methyl-propionyl)-piperazin-1...)
Show SMILES CC(C)(O)C(=O)N1CCN(CC1)c1ccc(c(c1)C1=C(C(=O)NC1=O)c1c[nH]c2ccccc12)C(F)(F)F
Show InChI InChI=1S/C27H25F3N4O4/c1-26(2,38)25(37)34-11-9-33(10-12-34)15-7-8-19(27(28,29)30)17(13-15)21-22(24(36)32-23(21)35)18-14-31-20-6-4-3-5-16(18)20/h3-8,13-14,31,38H,9-12H2,1-2H3,(H,32,35,36)
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Article
PubMed
n/an/a 1.02E+3n/an/an/an/a7.530



University of Luxembourg



Assay Description
Enzyme assay affinity-purified GST fusions of the active kinase domains (GST-Jak1(866-1154), GST-Jak2(808-1132), GST-Jak3(811-1124) and GST-Tyk2(888-...


Chem Biol 18: 314-23 (2011)


Article DOI: 10.1016/j.chembiol.2011.01.012
BindingDB Entry DOI: 10.7270/Q2736PDR
More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK1


(Homo sapiens (Human))
BDBM198605
PNG
(US9216999, 398b | US9556187, Example 398b)
Show SMILES CN[C@H]1CC[C@@H](CC1)c1nnn2cnc3[nH]ccc3c12
Show InChI InChI=1S/C14H18N6/c1-15-10-4-2-9(3-5-10)12-13-11-6-7-16-14(11)17-8-20(13)19-18-12/h6-10,15-16H,2-5H2,1H3/t9-,10-
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n/an/a 29n/an/an/an/a7.5n/a



Nissan Chemical Industries, Ltd.

US Patent


Assay Description
JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...


US Patent US9216999 (2015)


BindingDB Entry DOI: 10.7270/Q28C9V2J
More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK1


(Homo sapiens (Human))
BDBM198606
PNG
(US9216999, 399b | US9556187, Example 399b)
Show SMILES FC(F)CN[C@H]1CC[C@@H](CC1)c1nnn2cnc3[nH]ccc3c12
Show InChI InChI=1S/C15H18F2N6/c16-12(17)7-19-10-3-1-9(2-4-10)13-14-11-5-6-18-15(11)20-8-23(14)22-21-13/h5-6,8-10,12,18-19H,1-4,7H2/t9-,10-
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n/an/a 7.5n/an/an/an/a7.5n/a



Nissan Chemical Industries, Ltd.

US Patent


Assay Description
JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...


US Patent US9216999 (2015)


BindingDB Entry DOI: 10.7270/Q28C9V2J
More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK1


(Homo sapiens (Human))
BDBM198607
PNG
(US9216999, 400b | US9556187, Example 400b)
Show SMILES FC(F)(F)C(N[C@H]1CC[C@@H](CC1)c1nnn2cnc3[nH]ccc3c12)C(F)(F)F
Show InChI InChI=1S/C16H16F6N6/c17-15(18,19)14(16(20,21)22)25-9-3-1-8(2-4-9)11-12-10-5-6-23-13(10)24-7-28(12)27-26-11/h5-9,14,23,25H,1-4H2/t8-,9-
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n/an/a 42n/an/an/an/a7.5n/a



Nissan Chemical Industries, Ltd.

US Patent


Assay Description
JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...


US Patent US9216999 (2015)


BindingDB Entry DOI: 10.7270/Q28C9V2J
More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK1


(Homo sapiens (Human))
BDBM198608
PNG
(US9216999, 401 | US9556187, Example 401)
Show SMILES OC[C@H]1CC[C@H](CC1)c1nnn2cnc3[nH]ccc3c12
Show InChI InChI=1S/C14H17N5O/c20-7-9-1-3-10(4-2-9)12-13-11-5-6-15-14(11)16-8-19(13)18-17-12/h5-6,8-10,15,20H,1-4,7H2/t9-,10+
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n/an/a 12n/an/an/an/a7.5n/a



Nissan Chemical Industries, Ltd.

US Patent


Assay Description
JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...


US Patent US9216999 (2015)


BindingDB Entry DOI: 10.7270/Q28C9V2J
More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK1


(Homo sapiens (Human))
BDBM198609
PNG
(US9216999, 402 | US9556187, Example 402)
Show SMILES O=C[C@H]1CC[C@H](CC1)c1nnn2cnc3[nH]ccc3c12
Show InChI InChI=1S/C14H15N5O/c20-7-9-1-3-10(4-2-9)12-13-11-5-6-15-14(11)16-8-19(13)18-17-12/h5-10,15H,1-4H2/t9-,10+
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n/an/a 11n/an/an/an/a7.5n/a



Nissan Chemical Industries, Ltd.

US Patent


Assay Description
JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...


US Patent US9216999 (2015)


BindingDB Entry DOI: 10.7270/Q28C9V2J
More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK1


(Homo sapiens (Human))
BDBM198610
PNG
(US9216999, 403 | US9556187, Example 403)
Show SMILES OC1CN(C[C@H]2CC[C@H](CC2)c2nnn3cnc4[nH]ccc4c23)C1
Show InChI InChI=1S/C17H22N6O/c24-13-8-22(9-13)7-11-1-3-12(4-2-11)15-16-14-5-6-18-17(14)19-10-23(16)21-20-15/h5-6,10-13,18,24H,1-4,7-9H2/t11-,12+
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n/an/a 40n/an/an/an/a7.5n/a



Nissan Chemical Industries, Ltd.

US Patent


Assay Description
JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...


US Patent US9216999 (2015)


BindingDB Entry DOI: 10.7270/Q28C9V2J
More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK1


(Homo sapiens (Human))
BDBM198611
PNG
(US9216999, 404 | US9556187, Example 404)
Show SMILES O[C@H]1CCN(C[C@H]2CC[C@H](CC2)c2nnn3cnc4[nH]ccc4c23)C1
Show InChI InChI=1S/C18H24N6O/c25-14-6-8-23(10-14)9-12-1-3-13(4-2-12)16-17-15-5-7-19-18(15)20-11-24(17)22-21-16/h5,7,11-14,19,25H,1-4,6,8-10H2/t12-,13+,14-/m0/s1
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n/an/a 110n/an/an/an/a7.5n/a



Nissan Chemical Industries, Ltd.

US Patent


Assay Description
JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...


US Patent US9216999 (2015)


BindingDB Entry DOI: 10.7270/Q28C9V2J
More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK1


(Homo sapiens (Human))
BDBM198612
PNG
(US9216999, 405 | US9556187, Example 405)
Show SMILES O[C@@H]1CCN(C[C@H]2CC[C@H](CC2)c2nnn3cnc4[nH]ccc4c23)C1
Show InChI InChI=1S/C18H24N6O/c25-14-6-8-23(10-14)9-12-1-3-13(4-2-12)16-17-15-5-7-19-18(15)20-11-24(17)22-21-16/h5,7,11-14,19,25H,1-4,6,8-10H2/t12-,13+,14-/m1/s1
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n/an/a 25n/an/an/an/a7.5n/a



Nissan Chemical Industries, Ltd.

US Patent


Assay Description
JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...


US Patent US9216999 (2015)


BindingDB Entry DOI: 10.7270/Q28C9V2J
More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK1


(Homo sapiens (Human))
BDBM198613
PNG
(US9216999, 406 | US9556187, Example 406)
Show SMILES C(NC1CC1)[C@H]1CC[C@H](CC1)c1nnn2cnc3[nH]ccc3c12
Show InChI InChI=1S/C17H22N6/c1-3-12(4-2-11(1)9-19-13-5-6-13)15-16-14-7-8-18-17(14)20-10-23(16)22-21-15/h7-8,10-13,18-19H,1-6,9H2/t11-,12+
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n/an/a 83n/an/an/an/a7.5n/a



Nissan Chemical Industries, Ltd.

US Patent


Assay Description
JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...


US Patent US9216999 (2015)


BindingDB Entry DOI: 10.7270/Q28C9V2J
More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK1


(Homo sapiens (Human))
BDBM198614
PNG
(US9216999, 407 | US9556187, Example 407)
Show SMILES FC(F)(F)CN(C[C@H]1CC[C@@H](CC1)c1nnn2cnc3[nH]ccc3c12)C(=O)CC#N
Show InChI InChI=1S/C19H20F3N7O/c20-19(21,22)10-28(15(30)5-7-23)9-12-1-3-13(4-2-12)16-17-14-6-8-24-18(14)25-11-29(17)27-26-16/h6,8,11-13,24H,1-5,9-10H2/t12-,13-
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n/an/a 3.40n/an/an/an/a7.5n/a



Nissan Chemical Industries, Ltd.

US Patent


Assay Description
JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...


US Patent US9216999 (2015)


BindingDB Entry DOI: 10.7270/Q28C9V2J
More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK1


(Homo sapiens (Human))
BDBM198615
PNG
(US9216999, 408 | US9556187, Example 408)
Show SMILES O=C(CC#N)N(CC#N)C[C@H]1CC[C@@H](CC1)c1nnn2cnc3[nH]ccc3c12
Show InChI InChI=1S/C19H20N8O/c20-7-5-16(28)26(10-8-21)11-13-1-3-14(4-2-13)17-18-15-6-9-22-19(15)23-12-27(18)25-24-17/h6,9,12-14,22H,1-5,10-11H2/t13-,14-
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n/an/a 5.20n/an/an/an/a7.5n/a



Nissan Chemical Industries, Ltd.

US Patent


Assay Description
JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...


US Patent US9216999 (2015)


BindingDB Entry DOI: 10.7270/Q28C9V2J
More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK1


(Homo sapiens (Human))
BDBM198616
PNG
(US9216999, 409 | US9556187, Example 409)
Show SMILES O=C(CC#N)N(C[C@H]1CC[C@@H](CC1)c1nnn2cnc3[nH]ccc3c12)C1CC1
Show InChI InChI=1S/C20H23N7O/c21-9-7-17(28)26(15-5-6-15)11-13-1-3-14(4-2-13)18-19-16-8-10-22-20(16)23-12-27(19)25-24-18/h8,10,12-15,22H,1-7,11H2/t13-,14-
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n/an/a 19n/an/an/an/a7.5n/a



Nissan Chemical Industries, Ltd.

US Patent


Assay Description
JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...


US Patent US9216999 (2015)


BindingDB Entry DOI: 10.7270/Q28C9V2J
More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK1


(Homo sapiens (Human))
BDBM198617
PNG
(US9216999, 410 | US9556187, Example 410)
Show SMILES Cc1ccc(CN(C[C@H]2CC[C@@H](CC2)c2nnn3cnc4[nH]ccc4c23)C(=O)CC#N)o1
Show InChI InChI=1S/C23H25N7O2/c1-15-2-7-18(32-15)13-29(20(31)8-10-24)12-16-3-5-17(6-4-16)21-22-19-9-11-25-23(19)26-14-30(22)28-27-21/h2,7,9,11,14,16-17,25H,3-6,8,12-13H2,1H3/t16-,17-
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n/an/a 22n/an/an/an/a7.5n/a



Nissan Chemical Industries, Ltd.

US Patent


Assay Description
JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...


US Patent US9216999 (2015)


BindingDB Entry DOI: 10.7270/Q28C9V2J
More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK1


(Homo sapiens (Human))
BDBM198618
PNG
(US9216999, 411 | US9556187, Example 411)
Show SMILES FC(F)(F)CN(C[C@H]1CC[C@@H](CC1)c1nnn2cnc3[nH]ccc3c12)C(=O)CC(F)(F)F
Show InChI InChI=1S/C19H20F6N6O/c20-18(21,22)7-14(32)30(9-19(23,24)25)8-11-1-3-12(4-2-11)15-16-13-5-6-26-17(13)27-10-31(16)29-28-15/h5-6,10-12,26H,1-4,7-9H2/t11-,12-
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n/an/a 4.30n/an/an/an/a7.5n/a



Nissan Chemical Industries, Ltd.

US Patent


Assay Description
JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...


US Patent US9216999 (2015)


BindingDB Entry DOI: 10.7270/Q28C9V2J
More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK1


(Homo sapiens (Human))
BDBM198619
PNG
(US9216999, 412 | US9556187, Example 412)
Show SMILES FC(F)(F)CC(=O)N(CC#N)C[C@H]1CC[C@@H](CC1)c1nnn2cnc3[nH]ccc3c12
Show InChI InChI=1S/C19H20F3N7O/c20-19(21,22)9-15(30)28(8-6-23)10-12-1-3-13(4-2-12)16-17-14-5-7-24-18(14)25-11-29(17)27-26-16/h5,7,11-13,24H,1-4,8-10H2/t12-,13-
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n/an/a 2.60n/an/an/an/a7.5n/a



Nissan Chemical Industries, Ltd.

US Patent


Assay Description
JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...


US Patent US9216999 (2015)


BindingDB Entry DOI: 10.7270/Q28C9V2J
More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK1


(Homo sapiens (Human))
BDBM198620
PNG
(US9216999, 413 | US9556187, Example 413)
Show SMILES FC(F)(F)CN(CC1CC1)[C@H]1CC[C@@H](CC1)c1nnn2cnc3[nH]ccc3c12
Show InChI InChI=1S/C19H23F3N6/c20-19(21,22)10-27(9-12-1-2-12)14-5-3-13(4-6-14)16-17-15-7-8-23-18(15)24-11-28(17)26-25-16/h7-8,11-14,23H,1-6,9-10H2/t13-,14-
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n/an/a 20n/an/an/an/a7.5n/a



Nissan Chemical Industries, Ltd.

US Patent


Assay Description
JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...


US Patent US9216999 (2015)


BindingDB Entry DOI: 10.7270/Q28C9V2J
More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK1


(Homo sapiens (Human))
BDBM198621
PNG
(US9216999, 414 | US9556187, Example 414)
Show SMILES N#CCN(CC1CC1)C[C@H]1CC[C@@H](CC1)c1nnn2cnc3[nH]ccc3c12
Show InChI InChI=1S/C20H25N7/c21-8-10-26(11-14-1-2-14)12-15-3-5-16(6-4-15)18-19-17-7-9-22-20(17)23-13-27(19)25-24-18/h7,9,13-16,22H,1-6,10-12H2/t15-,16-
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Nissan Chemical Industries, Ltd.

US Patent


Assay Description
JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...


US Patent US9216999 (2015)


BindingDB Entry DOI: 10.7270/Q28C9V2J
More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK1


(Homo sapiens (Human))
BDBM198622
PNG
(US9216999, 415 | US9556187, Example 415)
Show SMILES FC(F)(F)CN(CC1CC1)C[C@H]1CC[C@@H](CC1)c1nnn2cnc3[nH]ccc3c12
Show InChI InChI=1S/C20H25F3N6/c21-20(22,23)11-28(9-13-1-2-13)10-14-3-5-15(6-4-14)17-18-16-7-8-24-19(16)25-12-29(18)27-26-17/h7-8,12-15,24H,1-6,9-11H2/t14-,15-
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Nissan Chemical Industries, Ltd.

US Patent


Assay Description
JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...


US Patent US9216999 (2015)


BindingDB Entry DOI: 10.7270/Q28C9V2J
More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK1


(Homo sapiens (Human))
BDBM198623
PNG
(US9216999, 416 | US9556187, Example 416)
Show SMILES OS(=O)(=O)C[C@H]1CC[C@@H](CC1)c1nnn2cnc3[nH]ccc3c12
Show InChI InChI=1S/C14H17N5O3S/c20-23(21,22)7-9-1-3-10(4-2-9)12-13-11-5-6-15-14(11)16-8-19(13)18-17-12/h5-6,8-10,15H,1-4,7H2,(H,20,21,22)/t9-,10-
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Nissan Chemical Industries, Ltd.

US Patent


Assay Description
JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...


US Patent US9216999 (2015)


BindingDB Entry DOI: 10.7270/Q28C9V2J
More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK1


(Homo sapiens (Human))
BDBM198624
PNG
(US9216999, 417 | US9556187, Example 417)
Show SMILES O=S(=O)(C[C@H]1CC[C@@H](CC1)c1nnn2cnc3[nH]ccc3c12)NC1CC1
Show InChI InChI=1S/C17H22N6O2S/c24-26(25,21-13-5-6-13)9-11-1-3-12(4-2-11)15-16-14-7-8-18-17(14)19-10-23(16)22-20-15/h7-8,10-13,18,21H,1-6,9H2/t11-,12-
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Nissan Chemical Industries, Ltd.

US Patent


Assay Description
JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...


US Patent US9216999 (2015)


BindingDB Entry DOI: 10.7270/Q28C9V2J
More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK1


(Homo sapiens (Human))
BDBM198625
PNG
(US9216999, 418 | US9556187, Example 418)
Show SMILES CN(C)S(=O)(=O)C[C@H]1CC[C@@H](CC1)c1nnn2cnc3[nH]ccc3c12
Show InChI InChI=1S/C16H22N6O2S/c1-21(2)25(23,24)9-11-3-5-12(6-4-11)14-15-13-7-8-17-16(13)18-10-22(15)20-19-14/h7-8,10-12,17H,3-6,9H2,1-2H3/t11-,12-
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Nissan Chemical Industries, Ltd.

US Patent


Assay Description
JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...


US Patent US9216999 (2015)


BindingDB Entry DOI: 10.7270/Q28C9V2J
More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK1


(Homo sapiens (Human))
BDBM198626
PNG
(US9216999, 419 | US9556187, Example 419)
Show SMILES O=S(=O)(C[C@H]1CC[C@@H](CC1)c1nnn2cnc3[nH]ccc3c12)NCC#N
Show InChI InChI=1S/C16H19N7O2S/c17-6-8-20-26(24,25)9-11-1-3-12(4-2-11)14-15-13-5-7-18-16(13)19-10-23(15)22-21-14/h5,7,10-12,18,20H,1-4,8-9H2/t11-,12-
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Nissan Chemical Industries, Ltd.

US Patent


Assay Description
JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...


US Patent US9216999 (2015)


BindingDB Entry DOI: 10.7270/Q28C9V2J
More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK1


(Homo sapiens (Human))
BDBM198627
PNG
(US9216999, 420 | US9556187, Example 420)
Show SMILES FC(F)(F)CNS(=O)(=O)C[C@H]1CC[C@@H](CC1)c1nnn2cnc3[nH]ccc3c12
Show InChI InChI=1S/C16H19F3N6O2S/c17-16(18,19)8-22-28(26,27)7-10-1-3-11(4-2-10)13-14-12-5-6-20-15(12)21-9-25(14)24-23-13/h5-6,9-11,20,22H,1-4,7-8H2/t10-,11-
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Nissan Chemical Industries, Ltd.

US Patent


Assay Description
JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...


US Patent US9216999 (2015)


BindingDB Entry DOI: 10.7270/Q28C9V2J
More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK1


(Homo sapiens (Human))
BDBM198628
PNG
(US9216999, 421 | US9556187, Example 421)
Show SMILES FC(F)(F)COC1CN(C[C@H]2CC[C@@H](CC2)c2nnn3cnc4[nH]ccc4c23)C1
Show InChI InChI=1S/C19H23F3N6O/c20-19(21,22)10-29-14-8-27(9-14)7-12-1-3-13(4-2-12)16-17-15-5-6-23-18(15)24-11-28(17)26-25-16/h5-6,11-14,23H,1-4,7-10H2/t12-,13-
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Nissan Chemical Industries, Ltd.

US Patent


Assay Description
JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...


US Patent US9216999 (2015)


BindingDB Entry DOI: 10.7270/Q28C9V2J
More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK1


(Homo sapiens (Human))
BDBM198629
PNG
(US9216999, 422 | US9556187, Example 422)
Show SMILES CC1(O)CN(C[C@H]2CC[C@@H](CC2)c2nnn3cnc4[nH]ccc4c23)C1
Show InChI InChI=1S/C18H24N6O/c1-18(25)9-23(10-18)8-12-2-4-13(5-3-12)15-16-14-6-7-19-17(14)20-11-24(16)22-21-15/h6-7,11-13,19,25H,2-5,8-10H2,1H3/t12-,13-
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Nissan Chemical Industries, Ltd.

US Patent


Assay Description
JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...


US Patent US9216999 (2015)


BindingDB Entry DOI: 10.7270/Q28C9V2J
More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK1


(Homo sapiens (Human))
BDBM198630
PNG
(US9216999, 423 | US9556187, Example 423)
Show SMILES CN(C)C1CN(C[C@H]2CC[C@@H](CC2)c2nnn3cnc4[nH]ccc4c23)C1
Show InChI InChI=1S/C19H27N7/c1-24(2)15-10-25(11-15)9-13-3-5-14(6-4-13)17-18-16-7-8-20-19(16)21-12-26(18)23-22-17/h7-8,12-15,20H,3-6,9-11H2,1-2H3/t13-,14-
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Nissan Chemical Industries, Ltd.

US Patent


Assay Description
JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...


US Patent US9216999 (2015)


BindingDB Entry DOI: 10.7270/Q28C9V2J
More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK1


(Homo sapiens (Human))
BDBM198631
PNG
(US9216999, 424 | US9556187, Example 424)
Show SMILES CCN(C)C1CN(C[C@H]2CC[C@@H](CC2)c2nnn3cnc4[nH]ccc4c23)C1
Show InChI InChI=1S/C20H29N7/c1-3-25(2)16-11-26(12-16)10-14-4-6-15(7-5-14)18-19-17-8-9-21-20(17)22-13-27(19)24-23-18/h8-9,13-16,21H,3-7,10-12H2,1-2H3/t14-,15-
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Nissan Chemical Industries, Ltd.

US Patent


Assay Description
JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...


US Patent US9216999 (2015)


BindingDB Entry DOI: 10.7270/Q28C9V2J
More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK1


(Homo sapiens (Human))
BDBM198632
PNG
(US9216999, 425 | US9556187, Example 425)
Show SMILES OC1(CN(C[C@H]2CC[C@@H](CC2)c2nnn3cnc4[nH]ccc4c23)C1)C(F)(F)F
Show InChI InChI=1S/C18H21F3N6O/c19-18(20,21)17(28)8-26(9-17)7-11-1-3-12(4-2-11)14-15-13-5-6-22-16(13)23-10-27(15)25-24-14/h5-6,10-12,22,28H,1-4,7-9H2/t11-,12-
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Nissan Chemical Industries, Ltd.

US Patent


Assay Description
JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...


US Patent US9216999 (2015)


BindingDB Entry DOI: 10.7270/Q28C9V2J
More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK1


(Homo sapiens (Human))
BDBM198633
PNG
(US9216999, 426 | US9556187, Example 426)
Show SMILES FC(F)(F)CNC(=O)C1CN(C[C@H]2CC[C@@H](CC2)c2nnn3cnc4[nH]ccc4c23)C1
Show InChI InChI=1S/C20H24F3N7O/c21-20(22,23)10-25-19(31)14-8-29(9-14)7-12-1-3-13(4-2-12)16-17-15-5-6-24-18(15)26-11-30(17)28-27-16/h5-6,11-14,24H,1-4,7-10H2,(H,25,31)/t12-,13-
PDB

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Nissan Chemical Industries, Ltd.

US Patent


Assay Description
JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...


US Patent US9216999 (2015)


BindingDB Entry DOI: 10.7270/Q28C9V2J
More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK1


(Homo sapiens (Human))
BDBM198634
PNG
(US9216999, 427 | US9556187, Example 427)
Show SMILES CS(=O)(=O)NC[C@H]1CC[C@@H](CC1)c1nnn2cnc3[nH]ccc3c12
Show InChI InChI=1S/C15H20N6O2S/c1-24(22,23)18-8-10-2-4-11(5-3-10)13-14-12-6-7-16-15(12)17-9-21(14)20-19-13/h6-7,9-11,16,18H,2-5,8H2,1H3/t10-,11-
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Nissan Chemical Industries, Ltd.

US Patent


Assay Description
JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...


US Patent US9216999 (2015)


BindingDB Entry DOI: 10.7270/Q28C9V2J
More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK1


(Homo sapiens (Human))
BDBM198635
PNG
(US9216999, 428 | US9556187, Example 428)
Show SMILES CC(C)(C)OC(=O)N1CC(CC#N)(C1)NC[C@H]1CC[C@@H](CC1)c1nnn2cnc3[nH]ccc3c12
Show InChI InChI=1S/C24H32N8O2/c1-23(2,3)34-22(33)31-13-24(14-31,9-10-25)28-12-16-4-6-17(7-5-16)19-20-18-8-11-26-21(18)27-15-32(20)30-29-19/h8,11,15-17,26,28H,4-7,9,12-14H2,1-3H3/t16-,17-
PDB

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Nissan Chemical Industries, Ltd.

US Patent


Assay Description
JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...


US Patent US9216999 (2015)


BindingDB Entry DOI: 10.7270/Q28C9V2J
More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK1


(Homo sapiens (Human))
BDBM198636
PNG
(US9216999, 429)
Show SMILES ON=C[C@H]1CC[C@@H](CC1)c1nnn2cnc3[nH]ccc3c12
Show InChI InChI=1S/C14H16N6O/c21-17-7-9-1-3-10(4-2-9)12-13-11-5-6-15-14(11)16-8-20(13)19-18-12/h5-10,15,21H,1-4H2/b17-7+/t9-,10-
PDB

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Nissan Chemical Industries, Ltd.

US Patent


Assay Description
JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...


US Patent US9216999 (2015)


BindingDB Entry DOI: 10.7270/Q28C9V2J
More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK1


(Homo sapiens (Human))
BDBM198637
PNG
(US9216999, 430 | US9556187, Example 430)
Show SMILES N#C[C@H]1CC[C@@H](CC1)c1nnn2cnc3[nH]ccc3c12
Show InChI InChI=1S/C14H14N6/c15-7-9-1-3-10(4-2-9)12-13-11-5-6-16-14(11)17-8-20(13)19-18-12/h5-6,8-10,16H,1-4H2/t9-,10-
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Nissan Chemical Industries, Ltd.

US Patent


Assay Description
JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...


US Patent US9216999 (2015)


BindingDB Entry DOI: 10.7270/Q28C9V2J
More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK1


(Homo sapiens (Human))
BDBM198638
PNG
(US9216999, 431 | US9556187, Example 431)
Show SMILES N#CC(=C[C@H]1CC[C@@H](CC1)c1nnn2cnc3[nH]ccc3c12)C#N
Show InChI InChI=1S/C17H15N7/c18-8-12(9-19)7-11-1-3-13(4-2-11)15-16-14-5-6-20-17(14)21-10-24(16)23-22-15/h5-7,10-11,13,20H,1-4H2/t11-,13-
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Nissan Chemical Industries, Ltd.

US Patent


Assay Description
JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...


US Patent US9216999 (2015)


BindingDB Entry DOI: 10.7270/Q28C9V2J
More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK1


(Homo sapiens (Human))
BDBM198639
PNG
(US9216999, 432 | US9556187, Example 432)
Show SMILES N#CC(C[C@H]1CC[C@@H](CC1)c1nnn2cnc3[nH]ccc3c12)C#N
Show InChI InChI=1S/C17H17N7/c18-8-12(9-19)7-11-1-3-13(4-2-11)15-16-14-5-6-20-17(14)21-10-24(16)23-22-15/h5-6,10-13,20H,1-4,7H2/t11-,13-
PDB

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Nissan Chemical Industries, Ltd.

US Patent


Assay Description
JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...


US Patent US9216999 (2015)


BindingDB Entry DOI: 10.7270/Q28C9V2J
More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK1


(Homo sapiens (Human))
BDBM198640
PNG
(US9216999, 433 | US9556187, Example 433)
Show SMILES C=C1CCC(CC1)c1nnn2cnc3[nH]ccc3c12
Show InChI InChI=1S/C14H15N5/c1-9-2-4-10(5-3-9)12-13-11-6-7-15-14(11)16-8-19(13)18-17-12/h6-8,10,15H,1-5H2
PDB

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Nissan Chemical Industries, Ltd.

US Patent


Assay Description
JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...


US Patent US9216999 (2015)


BindingDB Entry DOI: 10.7270/Q28C9V2J
More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK1


(Homo sapiens (Human))
BDBM198641
PNG
(US9216999, 434 | US9556187, Example 434)
Show SMILES N#CC=C1CCC(CC1)c1nnn2cnc3[nH]ccc3c12
Show InChI InChI=1S/C15H14N6/c16-7-5-10-1-3-11(4-2-10)13-14-12-6-8-17-15(12)18-9-21(14)20-19-13/h5-6,8-9,11,17H,1-4H2/b10-5-
PDB

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UniChem
n/an/a 2.30n/an/an/an/a7.5n/a



Nissan Chemical Industries, Ltd.

US Patent


Assay Description
JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...


US Patent US9216999 (2015)


BindingDB Entry DOI: 10.7270/Q28C9V2J
More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK1


(Homo sapiens (Human))
BDBM198642
PNG
(US9216999, 435a | US9556187, Example 435a)
Show SMILES N#CC[C@H]1CC[C@H](CC1)c1nnn2cnc3[nH]ccc3c12
Show InChI InChI=1S/C15H16N6/c16-7-5-10-1-3-11(4-2-10)13-14-12-6-8-17-15(12)18-9-21(14)20-19-13/h6,8-11,17H,1-5H2/t10-,11+
PDB

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n/an/a 5.40n/an/an/an/a7.5n/a



Nissan Chemical Industries, Ltd.

US Patent


Assay Description
JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...


US Patent US9216999 (2015)


BindingDB Entry DOI: 10.7270/Q28C9V2J
More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK1


(Homo sapiens (Human))
BDBM198643
PNG
(US9216999, 435b | US9556187, Example 435b)
Show SMILES N#CC[C@H]1CC[C@@H](CC1)c1nnn2cnc3[nH]ccc3c12
Show InChI InChI=1S/C15H16N6/c16-7-5-10-1-3-11(4-2-10)13-14-12-6-8-17-15(12)18-9-21(14)20-19-13/h6,8-11,17H,1-5H2/t10-,11-
PDB

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n/an/a 0.110n/an/an/an/a7.5n/a



Nissan Chemical Industries, Ltd.

US Patent


Assay Description
JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...


US Patent US9216999 (2015)


BindingDB Entry DOI: 10.7270/Q28C9V2J
More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK1


(Homo sapiens (Human))
BDBM198644
PNG
(US9216999, 436 | US9556187, Example 436)
Show InChI InChI=1S/C17H19N5O2/c1-2-24-14(23)9-11-3-5-12(6-4-11)15-16-13-7-8-18-17(13)19-10-22(16)21-20-15/h7-10,12,18H,2-6H2,1H3/b11-9-
PDB

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n/an/a 35n/an/an/an/a7.5n/a



Nissan Chemical Industries, Ltd.

US Patent


Assay Description
JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...


US Patent US9216999 (2015)


BindingDB Entry DOI: 10.7270/Q28C9V2J
More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK1


(Homo sapiens (Human))
BDBM198645
PNG
(US9216999, 437 | US9556187, Example 437)
Show InChI InChI=1S/C16H16N6/c1-10(8-17)11-2-4-12(5-3-11)14-15-13-6-7-18-16(13)19-9-22(15)21-20-14/h6-7,9,12,18H,2-5H2,1H3/b11-10-
PDB

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n/an/a 20n/an/an/an/a7.5n/a



Nissan Chemical Industries, Ltd.

US Patent


Assay Description
JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...


US Patent US9216999 (2015)


BindingDB Entry DOI: 10.7270/Q28C9V2J
More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK1


(Homo sapiens (Human))
BDBM198646
PNG
(US9216999, 438 | US9556187, Example 438)
Show SMILES CCOC(=O)CC1CCC(CC1)c1nnn2cnc3[nH]ccc3c12
Show InChI InChI=1S/C17H21N5O2/c1-2-24-14(23)9-11-3-5-12(6-4-11)15-16-13-7-8-18-17(13)19-10-22(16)21-20-15/h7-8,10-12,18H,2-6,9H2,1H3
PDB

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n/an/a 17n/an/an/an/a7.5n/a



Nissan Chemical Industries, Ltd.

US Patent


Assay Description
JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...


US Patent US9216999 (2015)


BindingDB Entry DOI: 10.7270/Q28C9V2J
More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK1


(Homo sapiens (Human))
BDBM198647
PNG
(US9216999, 439a | US9556187, Example 439a)
Show SMILES CC(C#N)[C@H]1CC[C@H](CC1)c1nnn2cnc3[nH]ccc3c12
Show InChI InChI=1S/C16H18N6/c1-10(8-17)11-2-4-12(5-3-11)14-15-13-6-7-18-16(13)19-9-22(15)21-20-14/h6-7,9-12,18H,2-5H2,1H3/t10?,11-,12+
PDB

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n/an/a 130n/an/an/an/a7.5n/a



Nissan Chemical Industries, Ltd.

US Patent


Assay Description
JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...


US Patent US9216999 (2015)


BindingDB Entry DOI: 10.7270/Q28C9V2J
More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK1


(Homo sapiens (Human))
BDBM198648
PNG
(US9216999, 439b | US9556187, Example 439b)
Show SMILES CC(C#N)[C@H]1CC[C@@H](CC1)c1nnn2cnc3[nH]ccc3c12
Show InChI InChI=1S/C16H18N6/c1-10(8-17)11-2-4-12(5-3-11)14-15-13-6-7-18-16(13)19-9-22(15)21-20-14/h6-7,9-12,18H,2-5H2,1H3/t10?,11-,12-
PDB

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n/an/a 3.10n/an/an/an/a7.5n/a



Nissan Chemical Industries, Ltd.

US Patent


Assay Description
JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...


US Patent US9216999 (2015)


BindingDB Entry DOI: 10.7270/Q28C9V2J
More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK1


(Homo sapiens (Human))
BDBM198649
PNG
(US9216999, 440 | US9556187, Example 440)
Show SMILES N#C\C=C\[C@H]1CC[C@@H](CC1)c1nnn2cnc3[nH]ccc3c12
Show InChI InChI=1S/C16H16N6/c17-8-1-2-11-3-5-12(6-4-11)14-15-13-7-9-18-16(13)19-10-22(15)21-20-14/h1-2,7,9-12,18H,3-6H2/b2-1+/t11-,12-
PDB

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n/an/a 5.30n/an/an/an/a7.5n/a



Nissan Chemical Industries, Ltd.

US Patent


Assay Description
JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...


US Patent US9216999 (2015)


BindingDB Entry DOI: 10.7270/Q28C9V2J
More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK1


(Homo sapiens (Human))
BDBM198650
PNG
(US9216999, 441 | US9556187, Example 441)
Show SMILES N#CCC[C@H]1CC[C@@H](CC1)c1nnn2cnc3[nH]ccc3c12
Show InChI InChI=1S/C16H18N6/c17-8-1-2-11-3-5-12(6-4-11)14-15-13-7-9-18-16(13)19-10-22(15)21-20-14/h7,9-12,18H,1-6H2/t11-,12-
PDB

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n/an/a 1.60n/an/an/an/a7.5n/a



Nissan Chemical Industries, Ltd.

US Patent


Assay Description
JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...


US Patent US9216999 (2015)


BindingDB Entry DOI: 10.7270/Q28C9V2J
More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK1


(Homo sapiens (Human))
BDBM198651
PNG
(US9216999, 442a | US9556187, Example 442a)
Show SMILES FC(F)(F)CNC(=O)C[C@H]1CC[C@H](CC1)c1nnn2cnc3[nH]ccc3c12
Show InChI InChI=1S/C17H19F3N6O/c18-17(19,20)8-22-13(27)7-10-1-3-11(4-2-10)14-15-12-5-6-21-16(12)23-9-26(15)25-24-14/h5-6,9-11,21H,1-4,7-8H2,(H,22,27)/t10-,11+
PDB

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n/an/a 27n/an/an/an/a7.5n/a



Nissan Chemical Industries, Ltd.

US Patent


Assay Description
JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...


US Patent US9216999 (2015)


BindingDB Entry DOI: 10.7270/Q28C9V2J
More data for this
Ligand-Target Pair
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