BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 8 hits of ph data with Target = 'lens epithelium-derived growth factor p75'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
lens epithelium-derived growth factor p75


(Homo sapiens)
BDBM179831
PNG
(US9132129, Cpd012)
Show SMILES CCCC(C(O)=O)c1c(C)nc2cc3CCCc3cc2c1-c1ccc(C)cc1
Show InChI InChI=1S/C25H27NO2/c1-4-6-20(25(27)28)23-16(3)26-22-14-19-8-5-7-18(19)13-21(22)24(23)17-11-9-15(2)10-12-17/h9-14,20H,4-8H2,1-3H3,(H,27,28)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 4.40E+3n/an/an/an/a7.025



KATHOLIEKE UNIVERSITEIT LEUVEN

US Patent


Assay Description
An Homogeneous Time Resolved Fluorescence (HTRF) assay was performed in a manner similar to previous reports on HTRF protein protein assays as review...


US Patent US9132129 (2015)


BindingDB Entry DOI: 10.7270/Q2MC8XSH
More data for this
Ligand-Target Pair
lens epithelium-derived growth factor p75


(Homo sapiens)
BDBM179821
PNG
(US9132129, Cpd002)
Show SMILES Cc1ccc(cc1)-c1c(C(OC(C)(C)C)C(O)=O)c(C)nc2cc3CCCCc3cc12
Show InChI InChI=1S/C27H31NO3/c1-16-10-12-18(13-11-16)24-21-14-19-8-6-7-9-20(19)15-22(21)28-17(2)23(24)25(26(29)30)31-27(3,4)5/h10-15,25H,6-9H2,1-5H3,(H,29,30)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 550n/an/an/an/a7.025



KATHOLIEKE UNIVERSITEIT LEUVEN

US Patent


Assay Description
An Homogeneous Time Resolved Fluorescence (HTRF) assay was performed in a manner similar to previous reports on HTRF protein protein assays as review...


US Patent US9132129 (2015)


BindingDB Entry DOI: 10.7270/Q2MC8XSH
More data for this
Ligand-Target Pair
lens epithelium-derived growth factor p75


(Homo sapiens)
BDBM179866
PNG
(US9132129, Cpd047)
Show SMILES CCCC(C(O)=O)c1c(C)nc2c3ccccc3nn2c1-c1ccc(C)cc1
Show InChI InChI=1S/C23H23N3O2/c1-4-7-18(23(27)28)20-15(3)24-22-17-8-5-6-9-19(17)25-26(22)21(20)16-12-10-14(2)11-13-16/h5-6,8-13,18H,4,7H2,1-3H3,(H,27,28)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 3.10E+3n/an/an/an/a7.025



KATHOLIEKE UNIVERSITEIT LEUVEN

US Patent


Assay Description
An Homogeneous Time Resolved Fluorescence (HTRF) assay was performed in a manner similar to previous reports on HTRF protein protein assays as review...


US Patent US9132129 (2015)


BindingDB Entry DOI: 10.7270/Q2MC8XSH
More data for this
Ligand-Target Pair
lens epithelium-derived growth factor p75


(Homo sapiens)
BDBM179866
PNG
(US9132129, Cpd047)
Show SMILES CCCC(C(O)=O)c1c(C)nc2c3ccccc3nn2c1-c1ccc(C)cc1
Show InChI InChI=1S/C23H23N3O2/c1-4-7-18(23(27)28)20-15(3)24-22-17-8-5-6-9-19(17)25-26(22)21(20)16-12-10-14(2)11-13-16/h5-6,8-13,18H,4,7H2,1-3H3,(H,27,28)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 7.85E+3n/an/an/an/a7.44



KATHOLIEKE UNIVERSITEIT LEUVEN

US Patent


Assay Description
An AlphaScreen assay was performed according to the manufacturer's protocol (Perkin Elmer, Benelux). Reactions were performed in 25 ul final volume i...


US Patent US9132129 (2015)


BindingDB Entry DOI: 10.7270/Q2MC8XSH
More data for this
Ligand-Target Pair
lens epithelium-derived growth factor p75


(Homo sapiens)
BDBM179831
PNG
(US9132129, Cpd012)
Show SMILES CCCC(C(O)=O)c1c(C)nc2cc3CCCc3cc2c1-c1ccc(C)cc1
Show InChI InChI=1S/C25H27NO2/c1-4-6-20(25(27)28)23-16(3)26-22-14-19-8-5-7-18(19)13-21(22)24(23)17-11-9-15(2)10-12-17/h9-14,20H,4-8H2,1-3H3,(H,27,28)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 1.08E+3n/an/an/an/a7.44



KATHOLIEKE UNIVERSITEIT LEUVEN

US Patent


Assay Description
An AlphaScreen assay was performed according to the manufacturer's protocol (Perkin Elmer, Benelux). Reactions were performed in 25 ul final volume i...


US Patent US9132129 (2015)


BindingDB Entry DOI: 10.7270/Q2MC8XSH
More data for this
Ligand-Target Pair
lens epithelium-derived growth factor p75


(Homo sapiens)
BDBM179822
PNG
(US9132129, Cpd003)
Show SMILES CCCC(C(O)=O)c1c(C)nc2ccc3CCCCc3c2c1-c1ccc(C)cc1
Show InChI InChI=1S/C26H29NO2/c1-4-7-21(26(28)29)23-17(3)27-22-15-14-18-8-5-6-9-20(18)25(22)24(23)19-12-10-16(2)11-13-19/h10-15,21H,4-9H2,1-3H3,(H,28,29)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 470n/an/an/an/a7.44



KATHOLIEKE UNIVERSITEIT LEUVEN

US Patent


Assay Description
An AlphaScreen assay was performed according to the manufacturer's protocol (Perkin Elmer, Benelux). Reactions were performed in 25 ul final volume i...


US Patent US9132129 (2015)


BindingDB Entry DOI: 10.7270/Q2MC8XSH
More data for this
Ligand-Target Pair
lens epithelium-derived growth factor p75


(Homo sapiens)
BDBM179820
PNG
(US9132129, Cpd001)
Show SMILES CCCC(C(O)=O)c1c(C)nc2cc3CCCCc3cc2c1-c1ccc(C)cc1
Show InChI InChI=1S/C26H29NO2/c1-4-7-21(26(28)29)24-17(3)27-23-15-20-9-6-5-8-19(20)14-22(23)25(24)18-12-10-16(2)11-13-18/h10-15,21H,4-9H2,1-3H3,(H,28,29)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 470n/an/an/an/a7.44



KATHOLIEKE UNIVERSITEIT LEUVEN

US Patent


Assay Description
An AlphaScreen assay was performed according to the manufacturer's protocol (Perkin Elmer, Benelux). Reactions were performed in 25 ul final volume i...


US Patent US9132129 (2015)


BindingDB Entry DOI: 10.7270/Q2MC8XSH
More data for this
Ligand-Target Pair
lens epithelium-derived growth factor p75


(Homo sapiens)
BDBM179842
PNG
(US9132129, Cpd023)
Show SMILES CCCC(C(O)=O)c1c(C)nc2ccc3CCCc3c2c1-c1ccc(C)cc1
Show InChI InChI=1S/C25H27NO2/c1-4-6-20(25(27)28)22-16(3)26-21-14-13-17-7-5-8-19(17)24(21)23(22)18-11-9-15(2)10-12-18/h9-14,20H,4-8H2,1-3H3,(H,27,28)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 4.60E+3n/an/an/an/a7.44



KATHOLIEKE UNIVERSITEIT LEUVEN

US Patent


Assay Description
An AlphaScreen assay was performed according to the manufacturer's protocol (Perkin Elmer, Benelux). Reactions were performed in 25 ul final volume i...


US Patent US9132129 (2015)


BindingDB Entry DOI: 10.7270/Q2MC8XSH
More data for this
Ligand-Target Pair