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Compile Data Set for Download or QSAR

Found 2 hits of ph data with Target = 'pi3k$#948'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
pi3k$#948


(Homo sapiens (human))
BDBM261343
PNG
(US9707233, 363)
Show SMILES COc1c(cc(Cl)c(C#N)c1C1CN(C[C@@H](C)O)C1)[C@@H](C)n1nc(C)c2c(N)ncnc12
Show InChI InChI=1S/C22H26ClN7O2/c1-11(31)7-29-8-14(9-29)19-16(6-24)17(23)5-15(20(19)32-4)13(3)30-22-18(12(2)28-30)21(25)26-10-27-22/h5,10-11,13-14,31H,7-9H2,1-4H3,(H2,25,26,27)/t11-,13-/m1/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 125n/an/an/an/a6.725



Incyte Holdings Corporation; Incyte Corporation

US Patent


Assay Description
[γ-33P]ATP (10 mCi/mL) was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinase substrate, D-myo-Phosphatidylinositol 4,5-bisphosphate (Pt...


US Patent US9707233 (2017)

More data for this
Ligand-Target Pair
pi3k$#948


(Homo sapiens (human))
BDBM261342
PNG
(US9707233, 361)
Show SMILES COc1c(cc(Cl)c(C#N)c1C1CN(C[C@H](C)O)C1)[C@@H](C)n1nc(C)c2c(N)ncnc12
Show InChI InChI=1S/C22H26ClN7O2/c1-11(31)7-29-8-14(9-29)19-16(6-24)17(23)5-15(20(19)32-4)13(3)30-22-18(12(2)28-30)21(25)26-10-27-22/h5,10-11,13-14,31H,7-9H2,1-4H3,(H2,25,26,27)/t11-,13+/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a>500n/an/an/an/a6.725



Incyte Holdings Corporation; Incyte Corporation

US Patent


Assay Description
[γ-33P]ATP (10 mCi/mL) was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinase substrate, D-myo-Phosphatidylinositol 4,5-bisphosphate (Pt...


US Patent US9707233 (2017)

More data for this
Ligand-Target Pair