Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Liver Receptor Homolog 1 (Homo sapiens (human)) | BDBM22376![]() ((3aS,6aR)-4-cyclohexyl-5-[(4E)-oct-4-en-4-yl]-N-ph...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 12 | n/a | n/a | 7.5 | 22 |
University of Southampton | Assay Description The screen utilizes a ligand mediated co-factor interaction between purified bacterial expressed ligand binding domain of human LRH1 and a TIF2-deriv... | J Med Chem 49: 6652-5 (2006) Article DOI: 10.1021/jm060990k BindingDB Entry DOI: 10.7270/Q2930RGT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Liver Receptor Homolog 1 (Homo sapiens (human)) | BDBM22375![]() ((3aS,6aR)-4-butyl-5-[(4E)-oct-4-en-4-yl]-N-phenyl-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 22 | n/a | n/a | 7.5 | 22 |
University of Southampton | Assay Description The screen utilizes a ligand mediated co-factor interaction between purified bacterial expressed ligand binding domain of human LRH1 and a TIF2-deriv... | J Med Chem 49: 6652-5 (2006) Article DOI: 10.1021/jm060990k BindingDB Entry DOI: 10.7270/Q2930RGT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Liver Receptor Homolog 1 (Homo sapiens (human)) | BDBM22391![]() ((3aS,6aR)-N-(2,3-dimethylphenyl)-5-hexyl-4-phenyl-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 30 | n/a | n/a | 7.5 | 22 |
University of Southampton | Assay Description The screen utilizes a ligand mediated co-factor interaction between purified bacterial expressed ligand binding domain of human LRH1 and a TIF2-deriv... | J Med Chem 49: 6652-5 (2006) Article DOI: 10.1021/jm060990k BindingDB Entry DOI: 10.7270/Q2930RGT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Liver Receptor Homolog 1 (Homo sapiens (human)) | BDBM22385![]() ((3aS,6aR)-5-hexyl-N,4-diphenyl-1,2,3,3a,6,6a-hexah...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 31.6 | n/a | n/a | n/a | n/a |
University of Southampton Curated by ChEMBL | Assay Description Agonist activity at human LRH-1 receptor assessed as TIF2 737-757 peptide recruitment by TR-FRET assay relative to control | J Med Chem 54: 2266-81 (2011) Article DOI: 10.1021/jm1014296 BindingDB Entry DOI: 10.7270/Q29Z957P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Liver Receptor Homolog 1 (Homo sapiens (human)) | BDBM22385![]() ((3aS,6aR)-5-hexyl-N,4-diphenyl-1,2,3,3a,6,6a-hexah...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 34 | n/a | n/a | 7.5 | 22 |
University of Southampton | Assay Description The screen utilizes a ligand mediated co-factor interaction between purified bacterial expressed ligand binding domain of human LRH1 and a TIF2-deriv... | J Med Chem 49: 6652-5 (2006) Article DOI: 10.1021/jm060990k BindingDB Entry DOI: 10.7270/Q2930RGT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Liver Receptor Homolog 1 (Homo sapiens (human)) | BDBM22379![]() ((3aS,6aR)-4-(naphthalen-2-yl)-5-[(4E)-oct-4-en-4-y...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 60 | n/a | n/a | 7.5 | 22 |
University of Southampton | Assay Description The screen utilizes a ligand mediated co-factor interaction between purified bacterial expressed ligand binding domain of human LRH1 and a TIF2-deriv... | J Med Chem 49: 6652-5 (2006) Article DOI: 10.1021/jm060990k BindingDB Entry DOI: 10.7270/Q2930RGT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Liver Receptor Homolog 1 (Homo sapiens (human)) | BDBM22382![]() ((3aS,6aR)-5-(hexan-2-yl)-N,4-diphenyl-1,2,3,3a,6,6...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 70 | n/a | n/a | 7.5 | 22 |
University of Southampton | Assay Description The screen utilizes a ligand mediated co-factor interaction between purified bacterial expressed ligand binding domain of human LRH1 and a TIF2-deriv... | J Med Chem 49: 6652-5 (2006) Article DOI: 10.1021/jm060990k BindingDB Entry DOI: 10.7270/Q2930RGT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Liver Receptor Homolog 1 (Homo sapiens (human)) | BDBM22374![]() ((3aS,6aR)-4-methyl-5-[(4E)-oct-4-en-4-yl]-N-phenyl...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 90 | n/a | n/a | 7.5 | 22 |
University of Southampton | Assay Description The screen utilizes a ligand mediated co-factor interaction between purified bacterial expressed ligand binding domain of human LRH1 and a TIF2-deriv... | J Med Chem 49: 6652-5 (2006) Article DOI: 10.1021/jm060990k BindingDB Entry DOI: 10.7270/Q2930RGT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Liver Receptor Homolog 1 (Homo sapiens (human)) | BDBM22378![]() ((3aS,6aR)-4-(3-methoxyphenyl)-5-[(4E)-oct-4-en-4-y...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 100 | n/a | n/a | 7.5 | 22 |
University of Southampton | Assay Description The screen utilizes a ligand mediated co-factor interaction between purified bacterial expressed ligand binding domain of human LRH1 and a TIF2-deriv... | J Med Chem 49: 6652-5 (2006) Article DOI: 10.1021/jm060990k BindingDB Entry DOI: 10.7270/Q2930RGT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Liver Receptor Homolog 1 (Homo sapiens (human)) | BDBM50418312![]() (CHEMBL1765932) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 100 | n/a | n/a | n/a | n/a |
University of Southampton Curated by ChEMBL | Assay Description Agonist activity at human LRH-1 receptor assessed as TIF2 737-757 peptide recruitment by TR-FRET assay relative to control | J Med Chem 54: 2266-81 (2011) Article DOI: 10.1021/jm1014296 BindingDB Entry DOI: 10.7270/Q29Z957P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Liver Receptor Homolog 1 (Homo sapiens (human)) | BDBM22388![]() ((3aS,6aR)-N,4,5-triphenyl-1,2,3,3a,6,6a-hexahydrop...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 150 | n/a | n/a | 7.5 | 22 |
University of Southampton | Assay Description The screen utilizes a ligand mediated co-factor interaction between purified bacterial expressed ligand binding domain of human LRH1 and a TIF2-deriv... | J Med Chem 49: 6652-5 (2006) Article DOI: 10.1021/jm060990k BindingDB Entry DOI: 10.7270/Q2930RGT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Liver Receptor Homolog 1 (Homo sapiens (human)) | BDBM50418306![]() (CHEMBL1765955) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 158 | n/a | n/a | n/a | n/a |
University of Southampton Curated by ChEMBL | Assay Description Agonist activity at human LRH-1 receptor assessed as TIF2 737-757 peptide recruitment by TR-FRET assay relative to control | J Med Chem 54: 2266-81 (2011) Article DOI: 10.1021/jm1014296 BindingDB Entry DOI: 10.7270/Q29Z957P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Liver Receptor Homolog 1 (Homo sapiens (human)) | BDBM22377![]() ((3aS,6aR)-4-(4-bromophenyl)-5-[(4E)-oct-4-en-4-yl]...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 160 | n/a | n/a | 7.5 | 22 |
University of Southampton | Assay Description The screen utilizes a ligand mediated co-factor interaction between purified bacterial expressed ligand binding domain of human LRH1 and a TIF2-deriv... | J Med Chem 49: 6652-5 (2006) Article DOI: 10.1021/jm060990k BindingDB Entry DOI: 10.7270/Q2930RGT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Liver Receptor Homolog 1 (Homo sapiens (human)) | BDBM50418304![]() (CHEMBL1765953) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 200 | n/a | n/a | n/a | n/a |
University of Southampton Curated by ChEMBL | Assay Description Agonist activity at human LRH-1 receptor assessed as TIF2 737-757 peptide recruitment by TR-FRET assay relative to control | J Med Chem 54: 2266-81 (2011) Article DOI: 10.1021/jm1014296 BindingDB Entry DOI: 10.7270/Q29Z957P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Liver Receptor Homolog 1 (Homo sapiens (human)) | BDBM22386![]() ((3aS,6aR)-5-cyclohexyl-N,4-diphenyl-1,2,3,3a,6,6a-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 230 | n/a | n/a | 7.5 | 22 |
University of Southampton | Assay Description The screen utilizes a ligand mediated co-factor interaction between purified bacterial expressed ligand binding domain of human LRH1 and a TIF2-deriv... | J Med Chem 49: 6652-5 (2006) Article DOI: 10.1021/jm060990k BindingDB Entry DOI: 10.7270/Q2930RGT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Liver Receptor Homolog 1 (Homo sapiens (human)) | BDBM50418309![]() (CHEMBL1765956) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 251 | n/a | n/a | n/a | n/a |
University of Southampton Curated by ChEMBL | Assay Description Agonist activity at human LRH-1 receptor assessed as TIF2 737-757 peptide recruitment by TR-FRET assay relative to control | J Med Chem 54: 2266-81 (2011) Article DOI: 10.1021/jm1014296 BindingDB Entry DOI: 10.7270/Q29Z957P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Liver Receptor Homolog 1 (Homo sapiens (human)) | BDBM50418313![]() (CHEMBL1765945) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 251 | n/a | n/a | n/a | n/a |
University of Southampton Curated by ChEMBL | Assay Description Agonist activity at human LRH-1 receptor assessed as TIF2 737-757 peptide recruitment by TR-FRET assay relative to control | J Med Chem 54: 2266-81 (2011) Article DOI: 10.1021/jm1014296 BindingDB Entry DOI: 10.7270/Q29Z957P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Liver Receptor Homolog 1 (Homo sapiens (human)) | BDBM50418308![]() (CHEMBL1765933) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 251 | n/a | n/a | n/a | n/a |
University of Southampton Curated by ChEMBL | Assay Description Agonist activity at human LRH-1 receptor assessed as TIF2 737-757 peptide recruitment by TR-FRET assay relative to control | J Med Chem 54: 2266-81 (2011) Article DOI: 10.1021/jm1014296 BindingDB Entry DOI: 10.7270/Q29Z957P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Liver Receptor Homolog 1 (Homo sapiens (human)) | BDBM50418303![]() (CHEMBL1765959) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | n/a | n/a | 251 | n/a | n/a | n/a | n/a |
University of Southampton Curated by ChEMBL | Assay Description Agonist activity at human LRH-1 receptor assessed as TIF2 737-757 peptide recruitment by TR-FRET assay relative to control | J Med Chem 54: 2266-81 (2011) Article DOI: 10.1021/jm1014296 BindingDB Entry DOI: 10.7270/Q29Z957P | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
Liver Receptor Homolog 1 (Homo sapiens (human)) | BDBM50418310![]() (CHEMBL1765962) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 251 | n/a | n/a | n/a | n/a |
University of Southampton Curated by ChEMBL | Assay Description Agonist activity at human LRH-1 receptor assessed as TIF2 737-757 peptide recruitment by TR-FRET assay relative to control | J Med Chem 54: 2266-81 (2011) Article DOI: 10.1021/jm1014296 BindingDB Entry DOI: 10.7270/Q29Z957P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Liver Receptor Homolog 1 (Homo sapiens (human)) | BDBM50418325![]() (CHEMBL1765958) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 316 | n/a | n/a | n/a | n/a |
University of Southampton Curated by ChEMBL | Assay Description Agonist activity at human LRH-1 receptor assessed as TIF2 737-757 peptide recruitment by TR-FRET assay relative to control | J Med Chem 54: 2266-81 (2011) Article DOI: 10.1021/jm1014296 BindingDB Entry DOI: 10.7270/Q29Z957P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Liver Receptor Homolog 1 (Homo sapiens (human)) | BDBM50418307![]() (CHEMBL1765934) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 316 | n/a | n/a | n/a | n/a |
University of Southampton Curated by ChEMBL | Assay Description Agonist activity at human LRH-1 receptor assessed as TIF2 737-757 peptide recruitment by TR-FRET assay relative to control | J Med Chem 54: 2266-81 (2011) Article DOI: 10.1021/jm1014296 BindingDB Entry DOI: 10.7270/Q29Z957P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Liver Receptor Homolog 1 (Homo sapiens (human)) | BDBM22383![]() ((3aS,6aR)-5-(decan-2-yl)-N,4-diphenyl-1,2,3,3a,6,6...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 320 | n/a | n/a | 7.5 | 22 |
University of Southampton | Assay Description The screen utilizes a ligand mediated co-factor interaction between purified bacterial expressed ligand binding domain of human LRH1 and a TIF2-deriv... | J Med Chem 49: 6652-5 (2006) Article DOI: 10.1021/jm060990k BindingDB Entry DOI: 10.7270/Q2930RGT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Liver Receptor Homolog 1 (Homo sapiens (human)) | BDBM22389![]() ((3aS,6aR)-N-(3-fluorophenyl)-5-hexyl-4-phenyl-1,2,...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 330 | n/a | n/a | 7.5 | 22 |
University of Southampton | Assay Description The screen utilizes a ligand mediated co-factor interaction between purified bacterial expressed ligand binding domain of human LRH1 and a TIF2-deriv... | J Med Chem 49: 6652-5 (2006) Article DOI: 10.1021/jm060990k BindingDB Entry DOI: 10.7270/Q2930RGT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Liver Receptor Homolog 1 (Homo sapiens (human)) | BDBM50418326![]() (CHEMBL1765961) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 398 | n/a | n/a | n/a | n/a |
University of Southampton Curated by ChEMBL | Assay Description Agonist activity at human LRH-1 receptor assessed as TIF2 737-757 peptide recruitment by TR-FRET assay relative to control | J Med Chem 54: 2266-81 (2011) Article DOI: 10.1021/jm1014296 BindingDB Entry DOI: 10.7270/Q29Z957P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Liver Receptor Homolog 1 (Homo sapiens (human)) | BDBM50418305![]() (CHEMBL1765960) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | n/a | n/a | 398 | n/a | n/a | n/a | n/a |
University of Southampton Curated by ChEMBL | Assay Description Agonist activity at human LRH-1 receptor assessed as TIF2 737-757 peptide recruitment by TR-FRET assay relative to control | J Med Chem 54: 2266-81 (2011) Article DOI: 10.1021/jm1014296 BindingDB Entry DOI: 10.7270/Q29Z957P | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
Liver Receptor Homolog 1 (Homo sapiens (human)) | BDBM22373![]() ((3aS,6aR)-5-[(4E)-oct-4-en-4-yl]-N,4-diphenyl-1,2,...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | MMDB PC cid PC sid PDB UniChem Similars | MMDB PDB Article PubMed | n/a | n/a | n/a | n/a | 430 | n/a | n/a | 7.5 | 22 |
University of Southampton | Assay Description The screen utilizes a ligand mediated co-factor interaction between purified bacterial expressed ligand binding domain of human LRH1 and a TIF2-deriv... | J Med Chem 49: 6652-5 (2006) Article DOI: 10.1021/jm060990k BindingDB Entry DOI: 10.7270/Q2930RGT | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
Liver Receptor Homolog 1 (Homo sapiens (human)) | BDBM50418316![]() (CHEMBL1765966) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 501 | n/a | n/a | n/a | n/a |
University of Southampton Curated by ChEMBL | Assay Description Agonist activity at human LRH-1 receptor assessed as TIF2 737-757 peptide recruitment by TR-FRET assay relative to control | J Med Chem 54: 2266-81 (2011) Article DOI: 10.1021/jm1014296 BindingDB Entry DOI: 10.7270/Q29Z957P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Liver Receptor Homolog 1 (Homo sapiens (human)) | BDBM22373![]() ((3aS,6aR)-5-[(4E)-oct-4-en-4-yl]-N,4-diphenyl-1,2,...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | MMDB PC cid PC sid PDB UniChem Similars | MMDB PDB Article PubMed | n/a | n/a | n/a | n/a | 631 | n/a | n/a | n/a | n/a |
University of Southampton Curated by ChEMBL | Assay Description Agonist activity at human LRH-1 receptor assessed as TIF2 737-757 peptide recruitment by TR-FRET assay relative to control | J Med Chem 54: 2266-81 (2011) Article DOI: 10.1021/jm1014296 BindingDB Entry DOI: 10.7270/Q29Z957P | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
Liver Receptor Homolog 1 (Homo sapiens (human)) | BDBM50418329![]() (CHEMBL1765951) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 794 | n/a | n/a | n/a | n/a |
University of Southampton Curated by ChEMBL | Assay Description Agonist activity at human LRH-1 receptor assessed as TIF2 737-757 peptide recruitment by TR-FRET assay relative to control | J Med Chem 54: 2266-81 (2011) Article DOI: 10.1021/jm1014296 BindingDB Entry DOI: 10.7270/Q29Z957P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Liver Receptor Homolog 1 (Homo sapiens (human)) | BDBM50418311![]() (CHEMBL1765931) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 794 | n/a | n/a | n/a | n/a |
University of Southampton Curated by ChEMBL | Assay Description Agonist activity at human LRH-1 receptor assessed as TIF2 737-757 peptide recruitment by TR-FRET assay relative to control | J Med Chem 54: 2266-81 (2011) Article DOI: 10.1021/jm1014296 BindingDB Entry DOI: 10.7270/Q29Z957P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Liver Receptor Homolog 1 (Homo sapiens (human)) | BDBM50418321![]() (CHEMBL1765963) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a |
University of Southampton Curated by ChEMBL | Assay Description Agonist activity at human LRH-1 receptor assessed as TIF2 737-757 peptide recruitment by TR-FRET assay relative to control | J Med Chem 54: 2266-81 (2011) Article DOI: 10.1021/jm1014296 BindingDB Entry DOI: 10.7270/Q29Z957P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Liver Receptor Homolog 1 (Homo sapiens (human)) | BDBM50418330![]() (CHEMBL1765938) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a |
University of Southampton Curated by ChEMBL | Assay Description Agonist activity at human LRH-1 receptor assessed as TIF2 737-757 peptide recruitment by TR-FRET assay relative to control | J Med Chem 54: 2266-81 (2011) Article DOI: 10.1021/jm1014296 BindingDB Entry DOI: 10.7270/Q29Z957P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Liver Receptor Homolog 1 (Homo sapiens (human)) | BDBM22390![]() ((3aS,6aR)-N-(4-chlorophenyl)-5-hexyl-4-phenyl-1,2,...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 1.00E+3 | n/a | n/a | 7.5 | 22 |
University of Southampton | Assay Description The screen utilizes a ligand mediated co-factor interaction between purified bacterial expressed ligand binding domain of human LRH1 and a TIF2-deriv... | J Med Chem 49: 6652-5 (2006) Article DOI: 10.1021/jm060990k BindingDB Entry DOI: 10.7270/Q2930RGT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Liver Receptor Homolog 1 (Homo sapiens (human)) | BDBM22395![]() (N-[(3aS,6aR)-5-hexyl-4-phenyl-1,2,3,3a,6,6a-hexahy...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 1.20E+3 | n/a | n/a | 7.5 | 22 |
University of Southampton | Assay Description The screen utilizes a ligand mediated co-factor interaction between purified bacterial expressed ligand binding domain of human LRH1 and a TIF2-deriv... | J Med Chem 49: 6652-5 (2006) Article DOI: 10.1021/jm060990k BindingDB Entry DOI: 10.7270/Q2930RGT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Liver Receptor Homolog 1 (Homo sapiens (human)) | BDBM50418317![]() (CHEMBL1765950) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 1.26E+3 | n/a | n/a | n/a | n/a |
University of Southampton Curated by ChEMBL | Assay Description Agonist activity at human LRH-1 receptor assessed as TIF2 737-757 peptide recruitment by TR-FRET assay relative to control | J Med Chem 54: 2266-81 (2011) Article DOI: 10.1021/jm1014296 BindingDB Entry DOI: 10.7270/Q29Z957P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Liver Receptor Homolog 1 (Homo sapiens (human)) | BDBM50418324![]() (CHEMBL1765957) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 1.26E+3 | n/a | n/a | n/a | n/a |
University of Southampton Curated by ChEMBL | Assay Description Agonist activity at human LRH-1 receptor assessed as TIF2 737-757 peptide recruitment by TR-FRET assay relative to control | J Med Chem 54: 2266-81 (2011) Article DOI: 10.1021/jm1014296 BindingDB Entry DOI: 10.7270/Q29Z957P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Liver Receptor Homolog 1 (Homo sapiens (human)) | BDBM22380![]() ((3aS,6aR)-5-[(3E)-hex-3-en-3-yl]-N,4-diphenyl-1,2,...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 1.40E+3 | n/a | n/a | 7.5 | 22 |
University of Southampton | Assay Description The screen utilizes a ligand mediated co-factor interaction between purified bacterial expressed ligand binding domain of human LRH1 and a TIF2-deriv... | J Med Chem 49: 6652-5 (2006) Article DOI: 10.1021/jm060990k BindingDB Entry DOI: 10.7270/Q2930RGT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Liver Receptor Homolog 1 (Homo sapiens (human)) | BDBM50418314![]() (CHEMBL1765954) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 1.58E+3 | n/a | n/a | n/a | n/a |
University of Southampton Curated by ChEMBL | Assay Description Agonist activity at human LRH-1 receptor assessed as TIF2 737-757 peptide recruitment by TR-FRET assay relative to control | J Med Chem 54: 2266-81 (2011) Article DOI: 10.1021/jm1014296 BindingDB Entry DOI: 10.7270/Q29Z957P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Liver Receptor Homolog 1 (Homo sapiens (human)) | BDBM50418323![]() (CHEMBL1765964) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 1.58E+3 | n/a | n/a | n/a | n/a |
University of Southampton Curated by ChEMBL | Assay Description Agonist activity at human LRH-1 receptor assessed as TIF2 737-757 peptide recruitment by TR-FRET assay relative to control | J Med Chem 54: 2266-81 (2011) Article DOI: 10.1021/jm1014296 BindingDB Entry DOI: 10.7270/Q29Z957P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Liver Receptor Homolog 1 (Homo sapiens (human)) | BDBM50418315![]() (CHEMBL1765936) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a |
University of Southampton Curated by ChEMBL | Assay Description Agonist activity at human LRH-1 receptor assessed as TIF2 737-757 peptide recruitment by TR-FRET assay relative to control | J Med Chem 54: 2266-81 (2011) Article DOI: 10.1021/jm1014296 BindingDB Entry DOI: 10.7270/Q29Z957P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Liver Receptor Homolog 1 (Homo sapiens (human)) | BDBM22384![]() ((3aS,6aR)-5-methyl-N,4-diphenyl-1,2,3,3a,6,6a-hexa...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 2.10E+3 | n/a | n/a | 7.5 | 22 |
University of Southampton | Assay Description The screen utilizes a ligand mediated co-factor interaction between purified bacterial expressed ligand binding domain of human LRH1 and a TIF2-deriv... | J Med Chem 49: 6652-5 (2006) Article DOI: 10.1021/jm060990k BindingDB Entry DOI: 10.7270/Q2930RGT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Liver Receptor Homolog 1 (Homo sapiens (human)) | BDBM50418299![]() (CHEMBL1765926) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 2.51E+3 | n/a | n/a | n/a | n/a |
University of Southampton Curated by ChEMBL | Assay Description Agonist activity at human LRH-1 receptor assessed as TIF2 737-757 peptide recruitment by TR-FRET assay relative to control | J Med Chem 54: 2266-81 (2011) Article DOI: 10.1021/jm1014296 BindingDB Entry DOI: 10.7270/Q29Z957P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Liver Receptor Homolog 1 (Homo sapiens (human)) | BDBM50418318![]() (CHEMBL1765942) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 2.51E+3 | n/a | n/a | n/a | n/a |
University of Southampton Curated by ChEMBL | Assay Description Agonist activity at human LRH-1 receptor assessed as TIF2 737-757 peptide recruitment by TR-FRET assay relative to control | J Med Chem 54: 2266-81 (2011) Article DOI: 10.1021/jm1014296 BindingDB Entry DOI: 10.7270/Q29Z957P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Liver Receptor Homolog 1 (Homo sapiens (human)) | BDBM50418320![]() (CHEMBL1765927) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 2.51E+3 | n/a | n/a | n/a | n/a |
University of Southampton Curated by ChEMBL | Assay Description Agonist activity at human LRH-1 receptor assessed as TIF2 737-757 peptide recruitment by TR-FRET assay relative to control | J Med Chem 54: 2266-81 (2011) Article DOI: 10.1021/jm1014296 BindingDB Entry DOI: 10.7270/Q29Z957P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Liver Receptor Homolog 1 (Homo sapiens (human)) | BDBM50418319![]() (CHEMBL1765930) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 2.51E+3 | n/a | n/a | n/a | n/a |
University of Southampton Curated by ChEMBL | Assay Description Agonist activity at human LRH-1 receptor assessed as TIF2 737-757 peptide recruitment by TR-FRET assay relative to control | J Med Chem 54: 2266-81 (2011) Article DOI: 10.1021/jm1014296 BindingDB Entry DOI: 10.7270/Q29Z957P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Liver Receptor Homolog 1 (Homo sapiens (human)) | BDBM50418301![]() (CHEMBL1765928) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 3.16E+3 | n/a | n/a | n/a | n/a |
University of Southampton Curated by ChEMBL | Assay Description Agonist activity at human LRH-1 receptor assessed as TIF2 737-757 peptide recruitment by TR-FRET assay relative to control | J Med Chem 54: 2266-81 (2011) Article DOI: 10.1021/jm1014296 BindingDB Entry DOI: 10.7270/Q29Z957P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Liver Receptor Homolog 1 (Homo sapiens (human)) | BDBM50418300![]() (CHEMBL1765941) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 3.16E+3 | n/a | n/a | n/a | n/a |
University of Southampton Curated by ChEMBL | Assay Description Agonist activity at human LRH-1 receptor assessed as TIF2 737-757 peptide recruitment by TR-FRET assay relative to control | J Med Chem 54: 2266-81 (2011) Article DOI: 10.1021/jm1014296 BindingDB Entry DOI: 10.7270/Q29Z957P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Liver Receptor Homolog 1 (Homo sapiens (human)) | BDBM50418302![]() (CHEMBL1765929) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 5.01E+3 | n/a | n/a | n/a | n/a |
University of Southampton Curated by ChEMBL | Assay Description Agonist activity at human LRH-1 receptor assessed as TIF2 737-757 peptide recruitment by TR-FRET assay relative to control | J Med Chem 54: 2266-81 (2011) Article DOI: 10.1021/jm1014296 BindingDB Entry DOI: 10.7270/Q29Z957P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Liver Receptor Homolog 1 (Homo sapiens (human)) | BDBM22381![]() ((3aS,6aR)-5-[(6E)-dodec-6-en-6-yl]-N,4-diphenyl-1,...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | 7.5 | 22 |
University of Southampton | Assay Description The screen utilizes a ligand mediated co-factor interaction between purified bacterial expressed ligand binding domain of human LRH1 and a TIF2-deriv... | J Med Chem 49: 6652-5 (2006) Article DOI: 10.1021/jm060990k BindingDB Entry DOI: 10.7270/Q2930RGT | |||||||||||
More data for this Ligand-Target Pair |
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