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Compile Data Set for Download or QSAR

Found 1011 hits of ec50 data for polymerid = 4816   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
karyopherin alpha 2 (RAG cohort 1, importin alpha 1), isoform CRA_b


(Homo sapiens)
BDBM75103
PNG
(3-(1,3-benzothiazol-2-yl)-7-hydroxy-8-[(2-methyl-1...)
Show SMILES CC1CCCCN1Cc1c(O)ccc2c1occ(-c1nc3ccccc3s1)c2=O
Show InChI InChI=1S/C23H22N2O3S/c1-14-6-4-5-11-25(14)12-16-19(26)10-9-15-21(27)17(13-28-22(15)16)23-24-18-7-2-3-8-20(18)29-23/h2-3,7-10,13-14,26H,4-6,11-12H2,1H3
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n/an/an/an/a<380n/an/an/an/a



Broad Institute

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Assay Description
Keywords: Counterscreen, FRET assay, HTS, YIC probe, Dose response, Assay Overview: This is a fluorescence resonance energy transfer (FRET)-based b...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q280513R
More data for this
Ligand-Target Pair
karyopherin alpha 2 (RAG cohort 1, importin alpha 1), isoform CRA_b


(Homo sapiens)
BDBM30856
PNG
(1-(4-methylphenyl)-2,5-bis(oxidanylidene)dipyrido[...)
Show SMILES Cc1ccc(cc1)-n1c2nc3ccccn3c(=O)c2cc(C#N)c1=O
Show InChI InChI=1S/C19H12N4O2/c1-12-5-7-14(8-6-12)23-17-15(10-13(11-20)18(23)24)19(25)22-9-3-2-4-16(22)21-17/h2-10H,1H3
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n/an/an/an/a 720n/an/an/an/a



Broad Institute

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Assay Description
Keywords: Counterscreen, FRET assay, HTS, YIC probe, Dose response, Assay Overview: This is a fluorescence resonance energy transfer (FRET)-based b...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q280513R
More data for this
Ligand-Target Pair
karyopherin alpha 2 (RAG cohort 1, importin alpha 1), isoform CRA_b


(Homo sapiens)
BDBM75285
PNG
(3-[2-(2-methoxyphenyl)ethynyl]-10-methyl-9-acridin...)
Show SMILES COc1ccccc1C#Cc1ccc2c(c1)n(C)c1ccccc1c2=O
Show InChI InChI=1S/C23H17NO2/c1-24-20-9-5-4-8-18(20)23(25)19-14-12-16(15-21(19)24)11-13-17-7-3-6-10-22(17)26-2/h3-10,12,14-15H,1-2H3
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Broad Institute

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Keywords: Counterscreen, FRET assay, HTS, YIC probe, Dose response, Assay Overview: This is a fluorescence resonance energy transfer (FRET)-based b...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q280513R
More data for this
Ligand-Target Pair
karyopherin alpha 2 (RAG cohort 1, importin alpha 1), isoform CRA_b


(Homo sapiens)
BDBM55566
PNG
((Z)-2-cyano-N-[2-(1H-indol-3-yl)ethyl]-3-(5-piperi...)
Show SMILES O=C(NCCc1c[nH]c2ccccc12)C(=C/c1ccc(o1)N1CCCCC1)\C#N
Show InChI InChI=1S/C23H24N4O2/c24-15-18(14-19-8-9-22(29-19)27-12-4-1-5-13-27)23(28)25-11-10-17-16-26-21-7-3-2-6-20(17)21/h2-3,6-9,14,16,26H,1,4-5,10-13H2,(H,25,28)/b18-14-
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Keywords: Counterscreen, FRET assay, HTS, YIC probe, Dose response, Assay Overview: This is a fluorescence resonance energy transfer (FRET)-based b...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q280513R
More data for this
Ligand-Target Pair
karyopherin alpha 2 (RAG cohort 1, importin alpha 1), isoform CRA_b


(Homo sapiens)
BDBM74600
PNG
(MLS000041448 | N-(1-ethyl-8-methyl-3-pyrazolo[3,4-...)
Show SMILES CCn1nc(NC(=O)c2ccccn2)c2cc3cccc(C)c3nc12
Show InChI InChI=1S/C19H17N5O/c1-3-24-18-14(11-13-8-6-7-12(2)16(13)21-18)17(23-24)22-19(25)15-9-4-5-10-20-15/h4-11H,3H2,1-2H3,(H,22,23,25)
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n/an/an/an/a 862n/an/an/an/a



Broad Institute

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PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q280513R
More data for this
Ligand-Target Pair
karyopherin alpha 2 (RAG cohort 1, importin alpha 1), isoform CRA_b


(Homo sapiens)
BDBM60177
PNG
(4-(5-{(Z)-[1-(2-chlorobenzyl)-2,5-dioxoimidazolidi...)
Show SMILES Cc1cc(ccc1-c1ccc(\C=C2/NC(=O)N(Cc3ccccc3Cl)C2=O)o1)C(O)=O
Show InChI InChI=1S/C23H17ClN2O5/c1-13-10-14(22(28)29)6-8-17(13)20-9-7-16(31-20)11-19-21(27)26(23(30)25-19)12-15-4-2-3-5-18(15)24/h2-11H,12H2,1H3,(H,25,30)(H,28,29)/b19-11-
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Broad Institute

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Keywords: Counterscreen, FRET assay, HTS, YIC probe, Dose response, Assay Overview: This is a fluorescence resonance energy transfer (FRET)-based b...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q280513R
More data for this
Ligand-Target Pair
karyopherin alpha 2 (RAG cohort 1, importin alpha 1), isoform CRA_b


(Homo sapiens)
BDBM75083
PNG
(3-cyclohexyl-2-diazanyl-7-(phenylmethyl)-6,8-dihyd...)
Show SMILES NNc1nc2sc3CN(Cc4ccccc4)CCc3c2c(=O)n1C1CCCCC1
Show InChI InChI=1S/C22H27N5OS/c23-25-22-24-20-19(21(28)27(22)16-9-5-2-6-10-16)17-11-12-26(14-18(17)29-20)13-15-7-3-1-4-8-15/h1,3-4,7-8,16H,2,5-6,9-14,23H2,(H,24,25)
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n/an/an/an/a 918n/an/an/an/a



Broad Institute

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Keywords: Counterscreen, FRET assay, HTS, YIC probe, Dose response, Assay Overview: This is a fluorescence resonance energy transfer (FRET)-based b...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q280513R
More data for this
Ligand-Target Pair
karyopherin alpha 2 (RAG cohort 1, importin alpha 1), isoform CRA_b


(Homo sapiens)
BDBM56912
PNG
(1-benzyl-2-(2-furoylamino)-N-(2-methoxyethyl)pyrro...)
Show SMILES COCCNC(=O)c1c(NC(=O)c2ccco2)n(Cc2ccccc2)c2nc3ccccc3nc12
Show InChI InChI=1S/C26H23N5O4/c1-34-15-13-27-26(33)21-22-24(29-19-11-6-5-10-18(19)28-22)31(16-17-8-3-2-4-9-17)23(21)30-25(32)20-12-7-14-35-20/h2-12,14H,13,15-16H2,1H3,(H,27,33)(H,30,32)
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Broad Institute

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Keywords: Counterscreen, FRET assay, HTS, YIC probe, Dose response, Assay Overview: This is a fluorescence resonance energy transfer (FRET)-based b...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q280513R
More data for this
Ligand-Target Pair
karyopherin alpha 2 (RAG cohort 1, importin alpha 1), isoform CRA_b


(Homo sapiens)
BDBM74553
PNG
(5,8-dimethyl-2-(1-pyrrolidinyl)-3-quinolinecarboni...)
Show SMILES Cc1ccc(C)c2nc(N3CCCC3)c(cc12)C#N
Show InChI InChI=1S/C16H17N3/c1-11-5-6-12(2)15-14(11)9-13(10-17)16(18-15)19-7-3-4-8-19/h5-6,9H,3-4,7-8H2,1-2H3
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n/an/an/an/a 1.21E+3n/an/an/an/a



Broad Institute

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Keywords: Counterscreen, FRET assay, HTS, YIC probe, Dose response, Assay Overview: This is a fluorescence resonance energy transfer (FRET)-based b...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q280513R
More data for this
Ligand-Target Pair
karyopherin alpha 2 (RAG cohort 1, importin alpha 1), isoform CRA_b


(Homo sapiens)
BDBM58584
PNG
(2-fluoro-4-(10-methyl-9-oxo-3-acridinyl)benzoic ac...)
Show SMILES CCOC(=O)c1ccc(cc1F)-c1ccc2c(c1)n(C)c1ccccc1c2=O
Show InChI InChI=1S/C23H18FNO3/c1-3-28-23(27)16-10-8-14(12-19(16)24)15-9-11-18-21(13-15)25(2)20-7-5-4-6-17(20)22(18)26/h4-13H,3H2,1-2H3
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n/an/an/an/a 1.29E+3n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: Counterscreen, FRET assay, HTS, YIC probe, Dose response, Assay Overview: This is a fluorescence resonance energy transfer (FRET)-based b...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q280513R
More data for this
Ligand-Target Pair
karyopherin alpha 2 (RAG cohort 1, importin alpha 1), isoform CRA_b


(Homo sapiens)
BDBM75040
PNG
(MLS000673318 | N'-{(1E)-[3-hydroxy-5-(hydroxym...)
Show SMILES COc1ccc(cc1)C(=O)NNCc1c(O)c(C)ncc1C=O
Show InChI InChI=1S/C16H17N3O4/c1-10-15(21)14(12(9-20)7-17-10)8-18-19-16(22)11-3-5-13(23-2)6-4-11/h3-7,9,18,21H,8H2,1-2H3,(H,19,22)
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n/an/an/an/a 1.52E+3n/an/an/an/a



Broad Institute

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Assay Description
Keywords: Counterscreen, FRET assay, HTS, YIC probe, Dose response, Assay Overview: This is a fluorescence resonance energy transfer (FRET)-based b...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q280513R
More data for this
Ligand-Target Pair
karyopherin alpha 2 (RAG cohort 1, importin alpha 1), isoform CRA_b


(Homo sapiens)
BDBM75085
PNG
((E)-2-Cyano-3-(9-methyl-4-oxo-2-phenoxy-4H-pyrido[...)
Show SMILES Cc1cccn2c1nc(Oc1ccccc1)c(\C=C(/C#N)C(N)=O)c2=O
Show InChI InChI=1S/C19H14N4O3/c1-12-6-5-9-23-17(12)22-18(26-14-7-3-2-4-8-14)15(19(23)25)10-13(11-20)16(21)24/h2-10H,1H3,(H2,21,24)/b13-10+
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n/an/an/an/a 1.58E+3n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: Counterscreen, FRET assay, HTS, YIC probe, Dose response, Assay Overview: This is a fluorescence resonance energy transfer (FRET)-based b...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q280513R
More data for this
Ligand-Target Pair
karyopherin alpha 2 (RAG cohort 1, importin alpha 1), isoform CRA_b


(Homo sapiens)
BDBM52272
PNG
(1-(3,4-dimethylphenyl)-2,5-bis(oxidanylidene)dipyr...)
Show SMILES Cc1ccc(cc1C)-n1c2nc3ccccn3c(=O)c2cc(C#N)c1=O
Show InChI InChI=1S/C20H14N4O2/c1-12-6-7-15(9-13(12)2)24-18-16(10-14(11-21)19(24)25)20(26)23-8-4-3-5-17(23)22-18/h3-10H,1-2H3
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n/an/an/an/a 1.78E+3n/an/an/an/a



Broad Institute

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Assay Description
Keywords: Counterscreen, FRET assay, HTS, YIC probe, Dose response, Assay Overview: This is a fluorescence resonance energy transfer (FRET)-based b...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q280513R
More data for this
Ligand-Target Pair
karyopherin alpha 2 (RAG cohort 1, importin alpha 1), isoform CRA_b


(Homo sapiens)
BDBM74787
PNG
(MLS000555563 | N-[2-(2-Amino-3-cyano-pyrrolo[2,3-b...)
Show SMILES Nc1c(C#N)c2nc3ccccc3nc2n1CCNC(=O)c1ccc(Cl)cc1
Show InChI InChI=1S/C20H15ClN6O/c21-13-7-5-12(6-8-13)20(28)24-9-10-27-18(23)14(11-22)17-19(27)26-16-4-2-1-3-15(16)25-17/h1-8H,9-10,23H2,(H,24,28)
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n/an/an/an/a 2.04E+3n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


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Keywords: Counterscreen, FRET assay, HTS, YIC probe, Dose response, Assay Overview: This is a fluorescence resonance energy transfer (FRET)-based b...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q280513R
More data for this
Ligand-Target Pair
karyopherin alpha 2 (RAG cohort 1, importin alpha 1), isoform CRA_b


(Homo sapiens)
BDBM74980
PNG
(3-[(E)-2-(4-chlorophenyl)ethenyl]imidazo[1,5-a]pyr...)
Show SMILES Clc1ccc(\C=C\c2ncc3ccccn23)cc1
Show InChI InChI=1S/C15H11ClN2/c16-13-7-4-12(5-8-13)6-9-15-17-11-14-3-1-2-10-18(14)15/h1-11H/b9-6+
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n/an/an/an/a 2.54E+3n/an/an/an/a



Broad Institute

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Assay Description
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PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q280513R
More data for this
Ligand-Target Pair
karyopherin alpha 2 (RAG cohort 1, importin alpha 1), isoform CRA_b


(Homo sapiens)
BDBM74846
PNG
((5Z)-1-(3-methylphenyl)-5-[(E)-3-phenylazanylprop-...)
Show SMILES Cc1cccc(c1)-n1c(O)c(C=CC=Nc2ccccc2)c(=O)[nH]c1=O
Show InChI InChI=1S/C20H17N3O3/c1-14-7-5-10-16(13-14)23-19(25)17(18(24)22-20(23)26)11-6-12-21-15-8-3-2-4-9-15/h2-13,25H,1H3,(H,22,24,26)/b11-6+,21-12+
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n/an/an/an/a 2.77E+3n/an/an/an/a



Broad Institute

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PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q280513R
More data for this
Ligand-Target Pair
karyopherin alpha 2 (RAG cohort 1, importin alpha 1), isoform CRA_b


(Homo sapiens)
BDBM75266
PNG
(6-chloranyl-3-[2-[4-(2,3-dihydro-1,4-benzodioxin-3...)
Show SMILES Cc1c(CC(=O)N2CCN(CC2)C(=O)C2COc3ccccc3O2)c(=O)oc2cc(O)c(Cl)cc12
Show InChI InChI=1S/C25H23ClN2O7/c1-14-15-10-17(26)18(29)12-21(15)35-25(32)16(14)11-23(30)27-6-8-28(9-7-27)24(31)22-13-33-19-4-2-3-5-20(19)34-22/h2-5,10,12,22,29H,6-9,11,13H2,1H3
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n/an/an/an/a 2.90E+3n/an/an/an/a



Broad Institute

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PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q280513R
More data for this
Ligand-Target Pair
karyopherin alpha 2 (RAG cohort 1, importin alpha 1), isoform CRA_b


(Homo sapiens)
BDBM70582
PNG
(2-Amino-1-benzo[1,3]dioxol-5-ylmethyl-1H-pyrrolo[2...)
Show SMILES CCCCNC(=O)c1c(N)n(Cc2ccc3OCOc3c2)c2nc3ccccc3nc12
Show InChI InChI=1S/C23H23N5O3/c1-2-3-10-25-23(29)19-20-22(27-16-7-5-4-6-15(16)26-20)28(21(19)24)12-14-8-9-17-18(11-14)31-13-30-17/h4-9,11H,2-3,10,12-13,24H2,1H3,(H,25,29)
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n/an/an/an/a 3.12E+3n/an/an/an/a



Broad Institute

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Assay Description
Keywords: Counterscreen, FRET assay, HTS, YIC probe, Dose response, Assay Overview: This is a fluorescence resonance energy transfer (FRET)-based b...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q280513R
More data for this
Ligand-Target Pair
karyopherin alpha 2 (RAG cohort 1, importin alpha 1), isoform CRA_b


(Homo sapiens)
BDBM52071
PNG
(6-Amino-8-(4-isopropoxy-3-methoxy-phenyl)-2-methyl...)
Show SMILES COc1cc(ccc1OC(C)C)C1C2CN(C)CCC2=C(C#N)C(=N)C1(C#N)C#N
Show InChI InChI=1S/C23H25N5O2/c1-14(2)30-19-6-5-15(9-20(19)29-4)21-18-11-28(3)8-7-16(18)17(10-24)22(27)23(21,12-25)13-26/h5-6,9,14,18,21,27H,7-8,11H2,1-4H3
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n/an/an/an/a 3.34E+3n/an/an/an/a



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Keywords: Counterscreen, FRET assay, HTS, YIC probe, Dose response, Assay Overview: This is a fluorescence resonance energy transfer (FRET)-based b...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q280513R
More data for this
Ligand-Target Pair
karyopherin alpha 2 (RAG cohort 1, importin alpha 1), isoform CRA_b


(Homo sapiens)
BDBM75027
PNG
(MLS000691875 | N-(5,6-dihydrobenzo[h]quinazolin-2-...)
Show SMILES CC(C)SCC(=O)Nc1ncc2CCc3ccccc3-c2n1
Show InChI InChI=1S/C17H19N3OS/c1-11(2)22-10-15(21)19-17-18-9-13-8-7-12-5-3-4-6-14(12)16(13)20-17/h3-6,9,11H,7-8,10H2,1-2H3,(H,18,19,20,21)
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n/an/an/an/a 3.48E+3n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: Counterscreen, FRET assay, HTS, YIC probe, Dose response, Assay Overview: This is a fluorescence resonance energy transfer (FRET)-based b...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q280513R
More data for this
Ligand-Target Pair
karyopherin alpha 2 (RAG cohort 1, importin alpha 1), isoform CRA_b


(Homo sapiens)
BDBM74784
PNG
(MLS000527782 | SMR000120356 | [4-[2-(3,5-dimethoxy...)
Show SMILES COc1cc(OC)cc(c1)-c1cc2nc(C)cc(N3CCN(CC3)C(=O)c3ccco3)n2n1
Show InChI InChI=1S/C24H25N5O4/c1-16-11-23(27-6-8-28(9-7-27)24(30)21-5-4-10-33-21)29-22(25-16)15-20(26-29)17-12-18(31-2)14-19(13-17)32-3/h4-5,10-15H,6-9H2,1-3H3
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n/an/an/an/a 3.68E+3n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: Counterscreen, FRET assay, HTS, YIC probe, Dose response, Assay Overview: This is a fluorescence resonance energy transfer (FRET)-based b...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q280513R
More data for this
Ligand-Target Pair
karyopherin alpha 2 (RAG cohort 1, importin alpha 1), isoform CRA_b


(Homo sapiens)
BDBM30737
PNG
(2-(2-amino-3-cyanopyrrolo[3,2-b]quinoxalin-1-yl)et...)
Show SMILES Nc1c(C#N)c2nc3ccccc3nc2n1CCOC(=O)c1ccc(Cl)cc1
Show InChI InChI=1S/C20H14ClN5O2/c21-13-7-5-12(6-8-13)20(27)28-10-9-26-18(23)14(11-22)17-19(26)25-16-4-2-1-3-15(16)24-17/h1-8H,9-10,23H2
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n/an/an/an/a 3.73E+3n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: Counterscreen, FRET assay, HTS, YIC probe, Dose response, Assay Overview: This is a fluorescence resonance energy transfer (FRET)-based b...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q280513R
More data for this
Ligand-Target Pair
karyopherin alpha 2 (RAG cohort 1, importin alpha 1), isoform CRA_b


(Homo sapiens)
BDBM75078
PNG
(10-[3-(diisoamylamino)-2-hydroxy-propyl]acridin-9-...)
Show SMILES CC(C)CCN(CCC(C)C)CC(O)Cn1c2ccccc2c(=O)c2ccccc12
Show InChI InChI=1S/C26H36N2O2/c1-19(2)13-15-27(16-14-20(3)4)17-21(29)18-28-24-11-7-5-9-22(24)26(30)23-10-6-8-12-25(23)28/h5-12,19-21,29H,13-18H2,1-4H3
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n/an/an/an/a 3.74E+3n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: Counterscreen, FRET assay, HTS, YIC probe, Dose response, Assay Overview: This is a fluorescence resonance energy transfer (FRET)-based b...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q280513R
More data for this
Ligand-Target Pair
karyopherin alpha 2 (RAG cohort 1, importin alpha 1), isoform CRA_b


(Homo sapiens)
BDBM75000
PNG
(2-methoxyethyl-[5-methyl-2-(p-tolyl)pyrazolo[1,5-a...)
Show SMILES COCCNc1cc(C)nc2cc(nn12)-c1ccc(C)cc1
Show InChI InChI=1S/C17H20N4O/c1-12-4-6-14(7-5-12)15-11-17-19-13(2)10-16(21(17)20-15)18-8-9-22-3/h4-7,10-11,18H,8-9H2,1-3H3
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n/an/an/an/a 3.77E+3n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: Counterscreen, FRET assay, HTS, YIC probe, Dose response, Assay Overview: This is a fluorescence resonance energy transfer (FRET)-based b...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q280513R
More data for this
Ligand-Target Pair
karyopherin alpha 2 (RAG cohort 1, importin alpha 1), isoform CRA_b


(Homo sapiens)
BDBM75094
PNG
((E)-2-Cyano-N-cyclohexyl-3-(5-morpholin-4-yl-furan...)
Show SMILES O=C(NC1CCCCC1)C(=C\c1ccc(o1)N1CCOCC1)\C#N
Show InChI InChI=1S/C18H23N3O3/c19-13-14(18(22)20-15-4-2-1-3-5-15)12-16-6-7-17(24-16)21-8-10-23-11-9-21/h6-7,12,15H,1-5,8-11H2,(H,20,22)/b14-12+
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n/an/an/an/a 3.85E+3n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: Counterscreen, FRET assay, HTS, YIC probe, Dose response, Assay Overview: This is a fluorescence resonance energy transfer (FRET)-based b...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q280513R
More data for this
Ligand-Target Pair
karyopherin alpha 2 (RAG cohort 1, importin alpha 1), isoform CRA_b


(Homo sapiens)
BDBM75260
PNG
(1-cyclohexyl-2-imino-10-methyl-3-(4-methylphenyl)s...)
Show SMILES Cc1ccc(cc1)S(=O)(=O)c1cc2c(nc3c(C)cccn3c2=O)n(C2CCCCC2)c1=N
Show InChI InChI=1S/C25H26N4O3S/c1-16-10-12-19(13-11-16)33(31,32)21-15-20-24(29(22(21)26)18-8-4-3-5-9-18)27-23-17(2)7-6-14-28(23)25(20)30/h6-7,10-15,18,26H,3-5,8-9H2,1-2H3
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n/an/an/an/a 3.87E+3n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: Counterscreen, FRET assay, HTS, YIC probe, Dose response, Assay Overview: This is a fluorescence resonance energy transfer (FRET)-based b...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q280513R
More data for this
Ligand-Target Pair
karyopherin alpha 2 (RAG cohort 1, importin alpha 1), isoform CRA_b


(Homo sapiens)
BDBM59056
PNG
((3Z)-2-(1,3-dihydrobenzimidazol-2-ylidene)-3-(3-hy...)
Show SMILES Oc1ccc(C=C(C#N)c2nc3ccccc3[nH]2)cc1O
Show InChI InChI=1S/C16H11N3O2/c17-9-11(7-10-5-6-14(20)15(21)8-10)16-18-12-3-1-2-4-13(12)19-16/h1-8,20-21H,(H,18,19)
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n/an/an/an/a 3.93E+3n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: Counterscreen, FRET assay, HTS, YIC probe, Dose response, Assay Overview: This is a fluorescence resonance energy transfer (FRET)-based b...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q280513R
More data for this
Ligand-Target Pair
karyopherin alpha 2 (RAG cohort 1, importin alpha 1), isoform CRA_b


(Homo sapiens)
BDBM55814
PNG
(5-[[5-(2,5-dichlorophenyl)-1H-pyrrol-2-yl]methylen...)
Show SMILES Clc1ccc(Cl)c(c1)-c1ccc(C=C2C(=O)NC(=O)NC2=O)[nH]1
Show InChI InChI=1S/C15H9Cl2N3O3/c16-7-1-3-11(17)9(5-7)12-4-2-8(18-12)6-10-13(21)19-15(23)20-14(10)22/h1-6,18H,(H2,19,20,21,22,23)
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n/an/an/an/a 4.04E+3n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: Counterscreen, FRET assay, HTS, YIC probe, Dose response, Assay Overview: This is a fluorescence resonance energy transfer (FRET)-based b...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q280513R
More data for this
Ligand-Target Pair
karyopherin alpha 2 (RAG cohort 1, importin alpha 1), isoform CRA_b


(Homo sapiens)
BDBM74898
PNG
(4-chloranyl-N'-[(E)-[4-(diethylamino)-6-oxidanylid...)
Show SMILES CCN(CC)c1ccc(C=NNC(=O)c2c(Cl)cnn2C)c(O)c1
Show InChI InChI=1S/C16H20ClN5O2/c1-4-22(5-2)12-7-6-11(14(23)8-12)9-18-20-16(24)15-13(17)10-19-21(15)3/h6-10,23H,4-5H2,1-3H3,(H,20,24)
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n/an/an/an/a 4.05E+3n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: Counterscreen, FRET assay, HTS, YIC probe, Dose response, Assay Overview: This is a fluorescence resonance energy transfer (FRET)-based b...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q280513R
More data for this
Ligand-Target Pair
karyopherin alpha 2 (RAG cohort 1, importin alpha 1), isoform CRA_b


(Homo sapiens)
BDBM68445
PNG
(MLS000084336 | SMR000048725 | cid_667374)
Show SMILES Cc1nc2nc(=O)c3C(C4=C(CC(C)(C)CC4=O)Nc3n2[nH]1)c1ccc(F)cc1
Show InChI InChI=1S/C21H20FN5O2/c1-10-23-20-25-19(29)17-15(11-4-6-12(22)7-5-11)16-13(24-18(17)27(20)26-10)8-21(2,3)9-14(16)28/h4-7,15,24H,8-9H2,1-3H3,(H,23,25,26,29)
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n/an/an/an/a 4.07E+3n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: Counterscreen, FRET assay, HTS, YIC probe, Dose response, Assay Overview: This is a fluorescence resonance energy transfer (FRET)-based b...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q280513R
More data for this
Ligand-Target Pair
karyopherin alpha 2 (RAG cohort 1, importin alpha 1), isoform CRA_b


(Homo sapiens)
BDBM75116
PNG
(4-cyano-1-keto-pyrido[2,1-b][1,3]benzothiazole-3-c...)
Show SMILES COC(=O)c1cc(=O)n2c(sc3ccccc23)c1C#N
Show InChI InChI=1S/C14H8N2O3S/c1-19-14(18)8-6-12(17)16-10-4-2-3-5-11(10)20-13(16)9(8)7-15/h2-6H,1H3
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n/an/an/an/a 4.11E+3n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: Counterscreen, FRET assay, HTS, YIC probe, Dose response, Assay Overview: This is a fluorescence resonance energy transfer (FRET)-based b...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q280513R
More data for this
Ligand-Target Pair
karyopherin alpha 2 (RAG cohort 1, importin alpha 1), isoform CRA_b


(Homo sapiens)
BDBM75070
PNG
(5-keto-2-nicotinoylimino-1-propyl-dipyrido[1,2-d:3...)
Show SMILES CCCn1c2nc3ccccn3c(=O)c2cc(C(=O)OCC)\c1=N/C(=O)c1cccnc1
Show InChI InChI=1S/C23H21N5O4/c1-3-11-28-19-16(22(30)27-12-6-5-9-18(27)25-19)13-17(23(31)32-4-2)20(28)26-21(29)15-8-7-10-24-14-15/h5-10,12-14H,3-4,11H2,1-2H3/b26-20+
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n/an/an/an/a 4.18E+3n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: Counterscreen, FRET assay, HTS, YIC probe, Dose response, Assay Overview: This is a fluorescence resonance energy transfer (FRET)-based b...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q280513R
More data for this
Ligand-Target Pair
karyopherin alpha 2 (RAG cohort 1, importin alpha 1), isoform CRA_b


(Homo sapiens)
BDBM68441
PNG
(MLS000084334 | SMR000048547 | cid_667200)
Show SMILES Cc1nc2nc(=O)c3C(C4=C(CC(C)(C)CC4=O)Nc3n2[nH]1)c1ccccc1
Show InChI InChI=1S/C21H21N5O2/c1-11-22-20-24-19(28)17-15(12-7-5-4-6-8-12)16-13(23-18(17)26(20)25-11)9-21(2,3)10-14(16)27/h4-8,15,23H,9-10H2,1-3H3,(H,22,24,25,28)
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n/an/an/an/a 4.30E+3n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: Counterscreen, FRET assay, HTS, YIC probe, Dose response, Assay Overview: This is a fluorescence resonance energy transfer (FRET)-based b...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q280513R
More data for this
Ligand-Target Pair
karyopherin alpha 2 (RAG cohort 1, importin alpha 1), isoform CRA_b


(Homo sapiens)
BDBM53311
PNG
(2-azanylidene-N-[2-(4-methoxyphenyl)ethyl]-10-meth...)
Show SMILES COc1ccc(CCNC(=O)c2cc3c(nc4c(C)cccn4c3=O)n(CCCN3CCOCC3)c2=N)cc1
Show InChI InChI=1S/C29H34N6O4/c1-20-5-3-13-35-26(20)32-27-24(29(35)37)19-23(25(30)34(27)14-4-12-33-15-17-39-18-16-33)28(36)31-11-10-21-6-8-22(38-2)9-7-21/h3,5-9,13,19,30H,4,10-12,14-18H2,1-2H3,(H,31,36)
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n/an/an/an/a 4.45E+3n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: Counterscreen, FRET assay, HTS, YIC probe, Dose response, Assay Overview: This is a fluorescence resonance energy transfer (FRET)-based b...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q280513R
More data for this
Ligand-Target Pair
karyopherin alpha 2 (RAG cohort 1, importin alpha 1), isoform CRA_b


(Homo sapiens)
BDBM53108
PNG
(2-[(6,7-dihydroxy-2-keto-chromen-4-yl)methylamino]...)
Show SMILES COC(=O)c1ccccc1NCc1cc(=O)oc2cc(O)c(O)cc12
Show InChI InChI=1S/C18H15NO6/c1-24-18(23)11-4-2-3-5-13(11)19-9-10-6-17(22)25-16-8-15(21)14(20)7-12(10)16/h2-8,19-21H,9H2,1H3
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n/an/an/an/a 4.53E+3n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: Counterscreen, FRET assay, HTS, YIC probe, Dose response, Assay Overview: This is a fluorescence resonance energy transfer (FRET)-based b...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q280513R
More data for this
Ligand-Target Pair
karyopherin alpha 2 (RAG cohort 1, importin alpha 1), isoform CRA_b


(Homo sapiens)
BDBM75160
PNG
(MLS001204417 | N-[2-(3-Cyano-6-methyl-quinolin-2-y...)
Show SMILES Cc1ccc2nc(NCCNC(=O)c3ccccc3)c(cc2c1)C#N
Show InChI InChI=1S/C20H18N4O/c1-14-7-8-18-16(11-14)12-17(13-21)19(24-18)22-9-10-23-20(25)15-5-3-2-4-6-15/h2-8,11-12H,9-10H2,1H3,(H,22,24)(H,23,25)
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n/an/an/an/a 4.66E+3n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: Counterscreen, FRET assay, HTS, YIC probe, Dose response, Assay Overview: This is a fluorescence resonance energy transfer (FRET)-based b...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q280513R
More data for this
Ligand-Target Pair
karyopherin alpha 2 (RAG cohort 1, importin alpha 1), isoform CRA_b


(Homo sapiens)
BDBM74979
PNG
(2-(9-acridinylamino)ethanol | 2-(acridin-9-ylamino...)
Show SMILES OCCNc1c2ccccc2nc2ccccc12
Show InChI InChI=1S/C15H14N2O/c18-10-9-16-15-11-5-1-3-7-13(11)17-14-8-4-2-6-12(14)15/h1-8,18H,9-10H2,(H,16,17)
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n/an/an/an/a 4.89E+3n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: Counterscreen, FRET assay, HTS, YIC probe, Dose response, Assay Overview: This is a fluorescence resonance energy transfer (FRET)-based b...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q280513R
More data for this
Ligand-Target Pair
karyopherin alpha 2 (RAG cohort 1, importin alpha 1), isoform CRA_b


(Homo sapiens)
BDBM61161
PNG
(5-bromanyl-N-[1-butyl-3-(phenylsulfonyl)pyrrolo[3,...)
Show SMILES CCCCn1c(NC(=O)c2ccc(Br)o2)c(c2nc3ccccc3nc12)S(=O)(=O)c1ccccc1
Show InChI InChI=1S/C25H21BrN4O4S/c1-2-3-15-30-23-21(27-17-11-7-8-12-18(17)28-23)22(35(32,33)16-9-5-4-6-10-16)24(30)29-25(31)19-13-14-20(26)34-19/h4-14H,2-3,15H2,1H3,(H,29,31)
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n/an/an/an/a 4.90E+3n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: Counterscreen, FRET assay, HTS, YIC probe, Dose response, Assay Overview: This is a fluorescence resonance energy transfer (FRET)-based b...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q280513R
More data for this
Ligand-Target Pair
karyopherin alpha 2 (RAG cohort 1, importin alpha 1), isoform CRA_b


(Homo sapiens)
BDBM74737
PNG
(5-(4-phenylmethoxyphenyl)-7-(trifluoromethyl)-[1,2...)
Show SMILES Nc1nc2nc(cc(n2n1)C(F)(F)F)-c1ccc(OCc2ccccc2)cc1
Show InChI InChI=1S/C19H14F3N5O/c20-19(21,22)16-10-15(24-18-25-17(23)26-27(16)18)13-6-8-14(9-7-13)28-11-12-4-2-1-3-5-12/h1-10H,11H2,(H2,23,26)
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n/an/an/an/a 4.98E+3n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: Counterscreen, FRET assay, HTS, YIC probe, Dose response, Assay Overview: This is a fluorescence resonance energy transfer (FRET)-based b...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q280513R
More data for this
Ligand-Target Pair
karyopherin alpha 2 (RAG cohort 1, importin alpha 1), isoform CRA_b


(Homo sapiens)
BDBM74829
PNG
((Z)-2-(morpholine-4-carbonyl)-3-(5-morpholin-4-ylf...)
Show SMILES O=C(N1CCOCC1)C(=C/c1ccc(o1)N1CCOCC1)\C#N
Show InChI InChI=1S/C16H19N3O4/c17-12-13(16(20)19-5-9-22-10-6-19)11-14-1-2-15(23-14)18-3-7-21-8-4-18/h1-2,11H,3-10H2/b13-11-
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n/an/an/an/a 5.08E+3n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: Counterscreen, FRET assay, HTS, YIC probe, Dose response, Assay Overview: This is a fluorescence resonance energy transfer (FRET)-based b...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q280513R
More data for this
Ligand-Target Pair
karyopherin alpha 2 (RAG cohort 1, importin alpha 1), isoform CRA_b


(Homo sapiens)
BDBM74544
PNG
(7,8-dimethyl-2-(1-pyrrolidinyl)-3-quinolinecarboni...)
Show SMILES Cc1ccc2cc(C#N)c(nc2c1C)N1CCCC1
Show InChI InChI=1S/C16H17N3/c1-11-5-6-13-9-14(10-17)16(18-15(13)12(11)2)19-7-3-4-8-19/h5-6,9H,3-4,7-8H2,1-2H3
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n/an/an/an/a 5.28E+3n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: Counterscreen, FRET assay, HTS, YIC probe, Dose response, Assay Overview: This is a fluorescence resonance energy transfer (FRET)-based b...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q280513R
More data for this
Ligand-Target Pair
karyopherin alpha 2 (RAG cohort 1, importin alpha 1), isoform CRA_b


(Homo sapiens)
BDBM74710
PNG
(8-(5-Phenyl-2-p-tolyl-pyrazolo[1,5-a]pyrimidin-7-y...)
Show SMILES Cc1ccc(cc1)-c1cc2nc(cc(N3CCC4(CC3)OCCO4)n2n1)-c1ccccc1
Show InChI InChI=1S/C26H26N4O2/c1-19-7-9-21(10-8-19)23-17-24-27-22(20-5-3-2-4-6-20)18-25(30(24)28-23)29-13-11-26(12-14-29)31-15-16-32-26/h2-10,17-18H,11-16H2,1H3
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n/an/an/an/a 5.56E+3n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: Counterscreen, FRET assay, HTS, YIC probe, Dose response, Assay Overview: This is a fluorescence resonance energy transfer (FRET)-based b...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q280513R
More data for this
Ligand-Target Pair
karyopherin alpha 2 (RAG cohort 1, importin alpha 1), isoform CRA_b


(Homo sapiens)
BDBM74773
PNG
(2-(allylamino)-4-amino-5-(5-bromothiophene-2-carbo...)
Show SMILES Nc1c(sc(NCC=C)c1C#N)C(=O)c1ccc(Br)s1
Show InChI InChI=1S/C13H10BrN3OS2/c1-2-5-17-13-7(6-15)10(16)12(20-13)11(18)8-3-4-9(14)19-8/h2-4,17H,1,5,16H2
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n/an/an/an/a 5.57E+3n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: Counterscreen, FRET assay, HTS, YIC probe, Dose response, Assay Overview: This is a fluorescence resonance energy transfer (FRET)-based b...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q280513R
More data for this
Ligand-Target Pair
karyopherin alpha 2 (RAG cohort 1, importin alpha 1), isoform CRA_b


(Homo sapiens)
BDBM74570
PNG
((8S,8aR)-6-amino-8-(7-methoxy-1,3-benzodioxol-5-yl...)
Show SMILES COc1cc(cc2OCOc12)[C@@H]1[C@H]2CN(C)CCC2=C(C#N)C(=N)C1(C#N)C#N
Show InChI InChI=1S/C21H19N5O3/c1-26-4-3-13-14(7-22)20(25)21(9-23,10-24)18(15(13)8-26)12-5-16(27-2)19-17(6-12)28-11-29-19/h5-6,15,18,25H,3-4,8,11H2,1-2H3/t15-,18+/m0/s1
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n/an/an/an/a 5.69E+3n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: Counterscreen, FRET assay, HTS, YIC probe, Dose response, Assay Overview: This is a fluorescence resonance energy transfer (FRET)-based b...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q280513R
More data for this
Ligand-Target Pair
karyopherin alpha 2 (RAG cohort 1, importin alpha 1), isoform CRA_b


(Homo sapiens)
BDBM59935
PNG
((E)-2-(Morpholine-4-carbonyl)-3-(5-morpholin-4-yl-...)
Show SMILES O=C(N1CCOCC1)C(=C\c1ccc(o1)N1CCOCC1)\C#N
Show InChI InChI=1S/C16H19N3O4/c17-12-13(16(20)19-5-9-22-10-6-19)11-14-1-2-15(23-14)18-3-7-21-8-4-18/h1-2,11H,3-10H2/b13-11+
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n/an/an/an/a 5.73E+3n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: Counterscreen, FRET assay, HTS, YIC probe, Dose response, Assay Overview: This is a fluorescence resonance energy transfer (FRET)-based b...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q280513R
More data for this
Ligand-Target Pair
karyopherin alpha 2 (RAG cohort 1, importin alpha 1), isoform CRA_b


(Homo sapiens)
BDBM75097
PNG
((E)-2-Cyano-3-[2-(4-methoxy-phenoxy)-9-methyl-4-ox...)
Show SMILES COc1ccc(Oc2nc3c(C)cccn3c(=O)c2\C=C(/C#N)C(N)=O)cc1
Show InChI InChI=1S/C20H16N4O4/c1-12-4-3-9-24-18(12)23-19(28-15-7-5-14(27-2)6-8-15)16(20(24)26)10-13(11-21)17(22)25/h3-10H,1-2H3,(H2,22,25)/b13-10+
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n/an/an/an/a 6.00E+3n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: Counterscreen, FRET assay, HTS, YIC probe, Dose response, Assay Overview: This is a fluorescence resonance energy transfer (FRET)-based b...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q280513R
More data for this
Ligand-Target Pair
karyopherin alpha 2 (RAG cohort 1, importin alpha 1), isoform CRA_b


(Homo sapiens)
BDBM75096
PNG
((E)-2-Cyano-3-(5-dimethylamino-furan-2-yl)-N-isopr...)
Show SMILES CC(C)NC(=O)C(=C\c1ccc(o1)N(C)C)\C#N
Show InChI InChI=1S/C13H17N3O2/c1-9(2)15-13(17)10(8-14)7-11-5-6-12(18-11)16(3)4/h5-7,9H,1-4H3,(H,15,17)/b10-7+
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n/an/an/an/a 6.38E+3n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: Counterscreen, FRET assay, HTS, YIC probe, Dose response, Assay Overview: This is a fluorescence resonance energy transfer (FRET)-based b...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q280513R
More data for this
Ligand-Target Pair
karyopherin alpha 2 (RAG cohort 1, importin alpha 1), isoform CRA_b


(Homo sapiens)
BDBM29681
PNG
(2-[(1,2,3,4-tetrafluoro-9-acridinyl)amino]ethanol ...)
Show SMILES OCCNc1c2ccccc2nc2c(F)c(F)c(F)c(F)c12
Show InChI InChI=1S/C15H10F4N2O/c16-10-9-14(20-5-6-22)7-3-1-2-4-8(7)21-15(9)13(19)12(18)11(10)17/h1-4,22H,5-6H2,(H,20,21)
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n/an/an/an/a 6.49E+3n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: Counterscreen, FRET assay, HTS, YIC probe, Dose response, Assay Overview: This is a fluorescence resonance energy transfer (FRET)-based b...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q280513R
More data for this
Ligand-Target Pair
karyopherin alpha 2 (RAG cohort 1, importin alpha 1), isoform CRA_b


(Homo sapiens)
BDBM33951
PNG
(3-amino-4,6-dimethyl-N-(p-anisylideneamino)thieno[...)
Show SMILES COc1ccc(C=NNC(=O)c2sc3nc(C)cc(C)c3c2N)cc1
Show InChI InChI=1S/C18H18N4O2S/c1-10-8-11(2)21-18-14(10)15(19)16(25-18)17(23)22-20-9-12-4-6-13(24-3)7-5-12/h4-9H,19H2,1-3H3,(H,22,23)
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n/an/an/an/a 6.59E+3n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: Counterscreen, FRET assay, HTS, YIC probe, Dose response, Assay Overview: This is a fluorescence resonance energy transfer (FRET)-based b...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q280513R
More data for this
Ligand-Target Pair
karyopherin alpha 2 (RAG cohort 1, importin alpha 1), isoform CRA_b


(Homo sapiens)
BDBM69006
PNG
(MLS000723009 | N-(2-fluorophenyl)-2-(9-ketoacridin...)
Show SMILES Fc1ccccc1NC(=O)Cn1c2ccccc2c(=O)c2ccccc12
Show InChI InChI=1S/C21H15FN2O2/c22-16-9-3-4-10-17(16)23-20(25)13-24-18-11-5-1-7-14(18)21(26)15-8-2-6-12-19(15)24/h1-12H,13H2,(H,23,25)
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n/an/an/an/a 6.63E+3n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: Counterscreen, FRET assay, HTS, YIC probe, Dose response, Assay Overview: This is a fluorescence resonance energy transfer (FRET)-based b...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q280513R
More data for this
Ligand-Target Pair
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