Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
insulin-degrading enzyme isoform 1 precursor (Homo sapiens) | BDBM50005641![]() (CHEMBL3235416) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | n/a | n/a | 530 | n/a | n/a | n/a | n/a |
INSERM Curated by ChEMBL | Assay Description Induction of human recombinant IDE-mediated insulin hydrolysis preincubated for 10 mins measured after 30 mins by spectrophotometer analysis | Eur J Med Chem 79: 184-93 (2014) Article DOI: 10.1016/j.ejmech.2014.04.009 BindingDB Entry DOI: 10.7270/Q27H1M34 | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) |