Compile Data Set for Download or QSAR
maximum 50k data
Found 66 of ec50 data for polymerid = 49000818,49000819,49000820,49000821
TargetNociceptin receptor(MOUSE)
TBA

Curated by ChEMBL
LigandPNGBDBM50333098(CHEMBL1631926)
Affinity DataEC50:  0.0400nMAssay Description:Agonist activity at NOR in mouse Neuro-2a cells assessed as stimulation of ERK phopshorylation after 30 mins post dose by Alphascreen Surefire assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(MOUSE)
TBA

Curated by ChEMBL
LigandPNGBDBM50333105(CHEMBL1631909 | H-FGGF(4-F)TGARKSARKLKNQ-NH2)
Affinity DataEC50:  0.360nMAssay Description:Agonist activity at NOR in mouse Neuro-2a cells assessed as stimulation of ERK phopshorylation after 30 mins post dose by Alphascreen Surefire assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(MOUSE)
TBA

Curated by ChEMBL
LigandPNGBDBM50475328(CHEMBL414782)
Affinity DataEC50:  0.437nMAssay Description:Inhibition of electrically evoked contraction of mouse vas deferensMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNociceptin receptor(MOUSE)
TBA

Curated by ChEMBL
LigandPNGBDBM50333095(CHEMBL1631923)
Affinity DataEC50:  0.610nMAssay Description:Agonist activity at NOR in mouse Neuro-2a cells assessed as stimulation of ERK phopshorylation after 30 mins post dose by Alphascreen Surefire assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(MOUSE)
TBA

Curated by ChEMBL
LigandPNGBDBM50475327(CHEMBL410653)
Affinity DataEC50:  0.759nMAssay Description:Inhibition of electrically evoked contraction of mouse vas deferensMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNociceptin receptor(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50274453(CHEMBL507847 | FGGFTGARKSARKRRNQ)
Affinity DataEC50:  0.980nMAssay Description:Activation of rat ORL1 receptor expressed in african green monkey COS7 cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(MOUSE)
TBA

Curated by ChEMBL
LigandPNGBDBM50475330(CHEMBL442297)
Affinity DataEC50:  1nMAssay Description:Inhibition of electrically evoked contraction of mouse vas deferensMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNociceptin receptor(MOUSE)
TBA

Curated by ChEMBL
LigandPNGBDBM50333098(CHEMBL1631926)
Affinity DataEC50:  1nMAssay Description:Agonist activity at NOR in mouse Neuro-2a cells assessed as stimulation of ERK phopshorylation after 30 mins post dose in presence of compound 14 by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50274449(CHEMBL505874 | FGGFTGARKSARKRKNQ)
Affinity DataEC50:  1.10nMAssay Description:Agonist activity at rat ORL1 receptor expressed in african green monkey COS7 cells assessed as stimulation of [35S]GTPgammaS binding by radioligand r...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50274449(CHEMBL505874 | FGGFTGARKSARKRKNQ)
Affinity DataEC50:  1.10nMAssay Description:Activation of rat ORL1 receptor expressed in african green monkey COS7 cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50274454(CHEMBL511107 | FGGFTGARKSARKKKNQ)
Affinity DataEC50:  1.10nMAssay Description:Activation of rat ORL1 receptor expressed in african green monkey COS7 cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50274452(CHEMBL506825 | FGGFTGARKSARKKRNQ)
Affinity DataEC50:  1.30nMAssay Description:Activation of rat ORL1 receptor expressed in african green monkey COS7 cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50296842(CHEMBL559130 | FGGFTGARKSARKWKNQ)
Affinity DataEC50:  1.30nMAssay Description:Agonist activity at rat ORL1 receptor expressed in african green monkey COS7 cells assessed as stimulation of [35S]GTPgammaS binding by radioligand r...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50296841(CHEMBL556388 | FGGFTGARKSARKWRNQ)
Affinity DataEC50:  1.30nMAssay Description:Agonist activity at rat ORL1 receptor expressed in african green monkey COS7 cells assessed as stimulation of [35S]GTPgammaS binding by radioligand r...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50274451(CHEMBL505824 | FGGFTGARKSARKRKRK)
Affinity DataEC50:  2.30nMAssay Description:Activation of rat ORL1 receptor expressed in african green monkey COS7 cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(MOUSE)
TBA

Curated by ChEMBL
LigandPNGBDBM50475333(CHEMBL264846)
Affinity DataEC50:  2.60nMAssay Description:Inhibition of electrically evoked contraction of mouse vas deferensMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNociceptin receptor(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50274450(CHEMBL499157 | FGGFTGARKSARKLARK)
Affinity DataEC50:  2.70nMAssay Description:Activation of rat ORL1 receptor expressed in african green monkey COS7 cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50296843(CHEMBL555757 | FGGFTGARKSARKRWNQ)
Affinity DataEC50:  3.10nMAssay Description:Agonist activity at rat ORL1 receptor expressed in african green monkey COS7 cells assessed as stimulation of [35S]GTPgammaS binding by radioligand r...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(MOUSE)
TBA

Curated by ChEMBL
LigandPNGBDBM50333108(CHEMBL1631922)
Affinity DataEC50:  3.10nMAssay Description:Agonist activity at NOR in mouse Neuro-2a cells assessed as stimulation of ERK phopshorylation after 30 mins post dose by Alphascreen Surefire assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50274462(CHEMBL526333 | FGGFTGARKSARKLRNQ)
Affinity DataEC50:  3.20nMAssay Description:Activation of rat ORL1 receptor expressed in african green monkey COS7 cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50296844(CHEMBL558807 | FGGFTGARKSARKKWNQ)
Affinity DataEC50:  3.20nMAssay Description:Agonist activity at rat ORL1 receptor expressed in african green monkey COS7 cells assessed as stimulation of [35S]GTPgammaS binding by radioligand r...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(MOUSE)
TBA

Curated by ChEMBL
LigandPNGBDBM50333107(CHEMBL1631921 | H-FGGFTGARKSARKAANQA-NH2)
Affinity DataEC50:  3.80nMAssay Description:Agonist activity at NOR in mouse Neuro-2a cells assessed as stimulation of ERK phopshorylation after 30 mins post dose by Alphascreen Surefire assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50274455(CHEMBL500773 | FGGFTGARKSARKRANQ)
Affinity DataEC50:  4nMAssay Description:Activation of rat ORL1 receptor expressed in african green monkey COS7 cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50274456(CHEMBL505632 | FGGFTGARKSARKKANQ)
Affinity DataEC50:  4.10nMAssay Description:Activation of rat ORL1 receptor expressed in african green monkey COS7 cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(MOUSE)
TBA

Curated by ChEMBL
LigandPNGBDBM50004178(Nociceptin | Nociceptin/orphanin FQ | ORPHANIN FQ)
Affinity DataEC50:  5.40nMAssay Description:Inhibition of electrically evoked contraction of mouse vas deferensMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50274461(CHEMBL504587 | FGGFTGARKSARKWANQ)
Affinity DataEC50:  5.80nMAssay Description:Agonist activity at rat ORL1 receptor expressed in african green monkey COS7 cells assessed as stimulation of [35S]GTPgammaS binding by radioligand r...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50274463(CHEMBL503512 | FGGFTGARKSARKLKNQ)
Affinity DataEC50:  5.80nMAssay Description:Activation of rat ORL1 receptor expressed in african green monkey COS7 cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50274461(CHEMBL504587 | FGGFTGARKSARKWANQ)
Affinity DataEC50:  5.80nMAssay Description:Activation of rat ORL1 receptor expressed in african green monkey COS7 cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM85191(Ac-RYYRWK-NH2 | CAS_200959-47-3)
Affinity DataEC50:  6.20nMAssay Description:Activity at Wistar rat NOP receptor assessed as inhibition of low-frequency electrically-stimulated vas deferens contraction in presence of naloxoneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50274459(CHEMBL524339 | FGGFTGARKSARKFANQ)
Affinity DataEC50:  9nMAssay Description:Activation of rat ORL1 receptor expressed in african green monkey COS7 cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50274464(CHEMBL504872 | FGGFTGARKSARKLLNQ)
Affinity DataEC50:  10nMAssay Description:Activation of rat ORL1 receptor expressed in african green monkey COS7 cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50274457(CHEMBL526352 | FGGFTGARKSARKAANQ)
Affinity DataEC50:  11nMAssay Description:Activation of rat ORL1 receptor expressed in african green monkey COS7 cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(MOUSE)
TBA

Curated by ChEMBL
LigandPNGBDBM50333104(CHEMBL389521 | H-FGGFTGARKSARKLANQ-NH2 | N/OFQ-NH2...)
Affinity DataEC50:  11nMAssay Description:Agonist activity at NOR in mouse Neuro-2a cells assessed as stimulation of ERK phopshorylation after 30 mins post dose by Alphascreen Surefire assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(MOUSE)
TBA

Curated by ChEMBL
LigandPNGBDBM50106479(CHEMBL384755 | FGGFTGARKSARK | H-FGGFTGARKSARK-NH2...)
Affinity DataEC50:  11nMAssay Description:Agonist activity at NOR in mouse Neuro-2a cells assessed as stimulation of ERK phopshorylation after 30 mins post dose by Alphascreen Surefire assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50274460(CHEMBL504540 | FGGFTGARKSARKYANQ | OFQ/N,[Tyr14])
Affinity DataEC50:  11nMAssay Description:Activation of rat ORL1 receptor expressed in african green monkey COS7 cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50274466(CHEMBL525604 | FGGFTGARKSARKLFNQ)
Affinity DataEC50:  12nMAssay Description:Activation of rat ORL1 receptor expressed in african green monkey COS7 cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50087692(8-Cyclodecyl-1-phenyl-1,3,8-triaza-spiro[4.5]decan...)
Affinity DataEC50:  13nMAssay Description:Inhibition of alpha4-beta1 VCAM binding in Jurkat cell adhesion assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50333104(CHEMBL389521 | H-FGGFTGARKSARKLANQ-NH2 | N/OFQ-NH2...)
Affinity DataEC50:  13nMAssay Description:Activation of rat ORL1 receptor expressed in african green monkey COS7 cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(MOUSE)
TBA

Curated by ChEMBL
LigandPNGBDBM50333096(CHEMBL1631924)
Affinity DataEC50:  14nMAssay Description:Agonist activity at NOR in mouse Neuro-2a cells assessed as stimulation of ERK phopshorylation after 30 mins post dose by Alphascreen Surefire assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50274458(CHEMBL524873 | FGGFTGARKSARKVANQ)
Affinity DataEC50:  15nMAssay Description:Activation of rat ORL1 receptor expressed in african green monkey COS7 cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM85191(Ac-RYYRWK-NH2 | CAS_200959-47-3)
Affinity DataEC50:  16nMAssay Description:Activity at Wistar rat NOP receptor assessed as inhibition of low-frequency electrically-stimulated vas deferens contractionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50274465(CHEMBL455289 | FGGFTGARKSARKLVNQ)
Affinity DataEC50:  30nMAssay Description:Activation of rat ORL1 receptor expressed in african green monkey COS7 cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(MOUSE)
TBA

Curated by ChEMBL
LigandPNGBDBM50333097(CHEMBL1631925)
Affinity DataEC50:  30nMAssay Description:Agonist activity at NOR in mouse Neuro-2a cells assessed as stimulation of ERK phopshorylation after 30 mins post dose by Alphascreen Surefire assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50274467(CHEMBL505873 | FGGFTGARKSARKLYNQ)
Affinity DataEC50:  33nMAssay Description:Activation of rat ORL1 receptor expressed in african green monkey COS7 cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50087691(8-(4-Isopropyl-cyclohexyl)-1-phenyl-1,3,8-triaza-s...)
Affinity DataEC50:  38nMAssay Description:Affinity for alpha4-beta1 integrin from HL60 cell lysateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50274468(CHEMBL510117 | FGGFTGARKSARKLWNQ)
Affinity DataEC50:  50nMAssay Description:Activation of rat ORL1 receptor expressed in african green monkey COS7 cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50274468(CHEMBL510117 | FGGFTGARKSARKLWNQ)
Affinity DataEC50:  50nMAssay Description:Agonist activity at rat ORL1 receptor expressed in african green monkey COS7 cells assessed as stimulation of [35S]GTPgammaS binding by radioligand r...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50106479(CHEMBL384755 | FGGFTGARKSARK | H-FGGFTGARKSARK-NH2...)
Affinity DataEC50:  51nMAssay Description:Activity at Wistar rat NOP receptor assessed as inhibition of low-frequency electrically-stimulated vas deferens contractionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM21842((2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-6-amino-2-[(2...)
Affinity DataEC50:  63nMAssay Description:Affinity for alpha4-beta1 integrin from HL60 cell lysateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50274448(CHEMBL504461 | FGGFTGARKRKRKLANQ)
Affinity DataEC50:  86nMAssay Description:Activation of rat ORL1 receptor expressed in african green monkey COS7 cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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