Compile Data Set for Download or QSAR
maximum 50k data
Found 8 of ec50 data for polymerid = 50004467,7499
TargetMicrotubule-associated protein tau(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50393082(CHEMBL2152858)
Affinity DataEC50:  24nMAssay Description:Inhibition of Tau phosphorylation by cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMicrotubule-associated protein tau(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50241461(3,7-bis(dimethylamino)phenothiazin-5-ium chloride ...)
Affinity DataEC50:  130nMAssay Description:Inhibition of tau-tau binding (unknown origin) assessed as increase in dissolved paired helical filamentsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMicrotubule-associated protein tau(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50393081(CHEMBL2152857)
Affinity DataEC50:  169nMAssay Description:Inhibition of Tau phosphorylation by cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMicrotubule-associated protein tau(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50393083(CHEMBL2152859)
Affinity DataEC50:  325nMAssay Description:Inhibition of Tau phosphorylation by cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMicrotubule-associated protein tau(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50241461(3,7-bis(dimethylamino)phenothiazin-5-ium chloride ...)
Affinity DataEC50:  590nMAssay Description:Inhibition of tau aggregation (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMicrotubule-associated protein tau(Rattus norvegicus)TBA
LigandPNGBDBM50487729(CHEMBL454948)
Affinity DataEC50:  2.90E+3nMAssay Description:Inhibition of microtubule polymerisation in Rattus norvegicus (rat) A10 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
TargetMicrotubule-associated protein tau(Rattus norvegicus)TBA
LigandPNGBDBM50487730(CHEMBL508222)
Affinity DataEC50:  4.40E+3nMAssay Description:Inhibition of microtubule polymerisation in Rattus norvegicus (rat) A10 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
TargetMicrotubule-associated protein tau(Rattus norvegicus)TBA
LigandPNGBDBM50340902((4-amino-2-(pyridin-3-ylamino)thiazol-5-yl)(2-fluo...)
Affinity DataEC50:  5.50E+3nMAssay Description:Inhibition of tau protein phosphorylation at Ser396 in rat brain cells at 0.5 to 50 uM after 4 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed