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Compile Data Set for Download or QSAR

Found 5 hits of ic50 data for polymerid = 10042   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Leucine aminopeptidase (LAP)


(Sus scrofa (Pig))
BDBM50457473
PNG
(CHEMBL4209822)
Show SMILES CC(C)C[C@@H]([C@H](O)C(=O)NO)C(=O)N[C@H](C(O)=O)c1ccccc1
Show InChI InChI=1S/C16H22N2O6/c1-9(2)8-11(13(19)15(21)18-24)14(20)17-12(16(22)23)10-6-4-3-5-7-10/h3-7,9,11-13,19,24H,8H2,1-2H3,(H,17,20)(H,18,21)(H,22,23)/t11-,12-,13-/m0/s1
GoogleScholar
UniChem
PubMed
n/an/a 30n/an/an/an/an/an/a



Jadavpur University

Curated by ChEMBL


Assay Description
Inhibition of porcine kidney leucine aminopeptidase using LGG as substrate after 90 mins


J Med Chem 61: 6468-6490 (2018)

More data for this
Ligand-Target Pair
Leucine aminopeptidase (LAP)


(Sus scrofa (Pig))
BDBM50457466
PNG
(CHEMBL4206158)
Show SMILES CC(C)C[C@@H]([C@H](O)C(=O)NO)C(=O)N[C@H](C(=O)OC1CCCC1)c1ccccc1
Show InChI InChI=1S/C21H30N2O6/c1-13(2)12-16(18(24)20(26)23-28)19(25)22-17(14-8-4-3-5-9-14)21(27)29-15-10-6-7-11-15/h3-5,8-9,13,15-18,24,28H,6-7,10-12H2,1-2H3,(H,22,25)(H,23,26)/t16-,17-,18-/m0/s1
GoogleScholar
UniChem
PubMed
n/an/a 100n/an/an/an/an/an/a



Jadavpur University

Curated by ChEMBL


Assay Description
Inhibition of porcine kidney leucine aminopeptidase using LGG as substrate after 90 mins


J Med Chem 61: 6468-6490 (2018)

More data for this
Ligand-Target Pair
Leucine aminopeptidase (LAP)


(Sus scrofa (Pig))
BDBM7460
PNG
(2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-4H-chrome...)
Show SMILES Oc1cc(O)c2c(c1)oc(-c1ccc(O)c(O)c1)c(O)c2=O
Show InChI InChI=1S/C15H10O7/c16-7-4-10(19)12-11(5-7)22-15(14(21)13(12)20)6-1-2-8(17)9(18)3-6/h1-5,16-19,21H
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CHEBI
CHEMBL
DrugBank
KEGG
MMDB
PC cid
PC sid
PDB
UniChem

Patents


Similars

Article
PubMed
n/an/a 3.43E+4n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of pig kidney cytosolic Leucyl aminopeptidase


J Nat Prod 58: 823-829 (1995)


Article DOI: 10.1021/np50120a001
BindingDB Entry DOI: 10.7270/Q2K937J6
More data for this
Ligand-Target Pair
Leucine aminopeptidase (LAP)


(Sus scrofa (Pig))
BDBM50157555
PNG
(2-(3,4-dihydroxyphenyl)-4H-chromen-4-one | 3',4'-d...)
Show SMILES Oc1ccc(cc1O)-c1cc(=O)c2ccccc2o1
Show InChI InChI=1S/C15H10O4/c16-11-6-5-9(7-13(11)18)15-8-12(17)10-3-1-2-4-14(10)19-15/h1-8,16,18H
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CHEMBL
MMDB
PC cid
PC sid
PDB
UniChem

Patents


Similars

Article
PubMed
n/an/a 3.51E+4n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of pig kidney cytosolic Leucyl aminopeptidase


J Nat Prod 58: 823-829 (1995)


Article DOI: 10.1021/np50120a001
BindingDB Entry DOI: 10.7270/Q2K937J6
More data for this
Ligand-Target Pair
Leucine aminopeptidase (LAP)


(Sus scrofa (Pig))
BDBM7459
PNG
(2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4H-chromen-4...)
Show SMILES Oc1cc(O)c2c(c1)oc(cc2=O)-c1ccc(O)c(O)c1
Show InChI InChI=1S/C15H10O6/c16-8-4-11(19)15-12(20)6-13(21-14(15)5-8)7-1-2-9(17)10(18)3-7/h1-6,16-19H
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CHEBI
CHEMBL
KEGG
MMDB
PC cid
PC sid
PDB
UniChem

Patents


Similars

Article
PubMed
n/an/a 4.96E+4n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of pig kidney cytosolic Leucyl aminopeptidase


J Nat Prod 58: 823-829 (1995)


Article DOI: 10.1021/np50120a001
BindingDB Entry DOI: 10.7270/Q2K937J6
More data for this
Ligand-Target Pair