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Compile Data Set for Download or QSAR

Found 368 hits of ic50 data for polymerid = 2200   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM50238903
PNG
(CHEMBL4077102)
Show SMILES CCN(CC)c1ccc2c(-c3ccccc3C(=O)N[C@@H](CCCCN)C(=O)N(CCC(=O)N[C@@H](CCCCN)C(=O)N(CCC(=O)N[C@@H](CCCCN)C(=O)N(CCC(=O)N[C@@H](CCCCN)C(=O)N(CCC(=O)N[C@@H](CCCCN)C(=O)N(CCC(=O)N[C@@H](CCCCN)C(=O)N(CCC(N)=O)Cc3ccc(F)cc3)Cc3ccc(F)cc3)Cc3ccc(F)cc3)Cc3ccc(F)cc3)Cc3ccc(F)cc3)Cc3ccc(F)cc3)c3ccc(cc3oc2c1)=[N+](CC)CC
Show InChI InChI=1/C124H163F6N21O14/c1-5-144(6-2)97-55-57-101-109(77-97)165-110-78-98(145(7-3)8-4)56-58-102(110)117(101)99-23-9-10-24-100(99)118(158)143-108(30-16-22-70-136)124(164)151(84-90-41-53-96(130)54-42-90)76-64-116(157)142-107(29-15-21-69-135)123(163)150(83-89-39-51-95(129)52-40-89)75-63-115(156)141-106(28-14-20-68-134)122(162)149(82-88-37-49-94(128)50-38-88)74-62-114(155)140-105(27-13-19-67-133)121(161)148(81-87-35-47-93(127)48-36-87)73-61-113(154)139-104(26-12-18-66-132)120(160)147(80-86-33-45-92(126)46-34-86)72-60-112(153)138-103(25-11-17-65-131)119(159)146(71-59-111(137)152)79-85-31-43-91(125)44-32-85/h9-10,23-24,31-58,77-78,103-108H,5-8,11-22,25-30,59-76,79-84,131-136H2,1-4H3,(H7-,137,138,139,140,141,142,143,152,153,154,155,156,157,158)/p+1/t103-,104-,105-,106-,107-,108-/s2
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n/an/a 10n/an/an/an/an/an/a



University of Copenhagen

Curated by ChEMBL


Assay Description
Antagonist activity at FPR2 in human peripheral blood polymorphonuclear neutrophils assessed as inhibition of WKYMVM-peptide induced ROS production p...


J Med Chem 60: 6991-6997 (2017)


Article DOI: 10.1021/acs.jmedchem.7b00489
BindingDB Entry DOI: 10.7270/Q2V40XFR
More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM50238899
PNG
(CHEMBL4066521)
Show SMILES CCN(CC)c1ccc2c(-c3ccccc3C(=O)N[C@@H](CCCCN)C(=O)N(CCC(=O)N[C@@H](CCCCN)C(=O)N(CCC(=O)N[C@@H](CCCCN)C(=O)N(CCC(=O)N[C@@H](CCCCN)C(=O)N(CCC(N)=O)Cc3ccccc3)Cc3ccccc3)Cc3ccccc3)Cc3ccccc3)c3ccc(cc3oc2c1)=[N+](CC)CC
Show InChI InChI=1/C92H123N15O10/c1-5-102(6-2)71-45-47-75-81(61-71)117-82-62-72(103(7-3)8-4)46-48-76(82)87(75)73-39-21-22-40-74(73)88(112)101-80(44-26-30-56-96)92(116)107(66-70-37-19-12-20-38-70)60-52-86(111)100-79(43-25-29-55-95)91(115)106(65-69-35-17-11-18-36-69)59-51-85(110)99-78(42-24-28-54-94)90(114)105(64-68-33-15-10-16-34-68)58-50-84(109)98-77(41-23-27-53-93)89(113)104(57-49-83(97)108)63-67-31-13-9-14-32-67/h9-22,31-40,45-48,61-62,77-80H,5-8,23-30,41-44,49-60,63-66,93-96H2,1-4H3,(H5-,97,98,99,100,101,108,109,110,111,112)/p+1/t77-,78-,79-,80-/s2
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n/an/a 13n/an/an/an/an/an/a



University of Copenhagen

Curated by ChEMBL


Assay Description
Opioid receptor mu 1 affinity against the receptor site model site 1 (mu1) by using the curve-fitting program LIGAND


J Med Chem 60: 6991-6997 (2017)


Article DOI: 10.1021/acs.jmedchem.7b00489
BindingDB Entry DOI: 10.7270/Q2V40XFR
More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM50238906
PNG
(CHEMBL4081147)
Show SMILES CCN(CC)c1ccc2c(-c3ccccc3C(=O)N[C@@H](CCCCN)C(=O)N(CCC(=O)N[C@@H](CCCCN)C(=O)N(CCC(=O)N[C@@H](CCCCN)C(=O)N(CCC(=O)N[C@@H](CCCCN)C(=O)N(CCC(=O)N[C@@H](CCCCN)C(=O)N(CCC(=O)N[C@@H](CCCCN)C(=O)N(CCC(N)=O)Cc3ccccc3)Cc3ccccc3)Cc3ccccc3)Cc3ccccc3)Cc3ccccc3)Cc3ccccc3)c3ccc(cc3oc2c1)=[N+](CC)CC
Show InChI InChI=1/C124H169N21O14/c1-5-138(6-2)97-61-63-101-109(83-97)159-110-84-98(139(7-3)8-4)62-64-102(110)117(101)99-53-27-28-54-100(99)118(152)137-108(60-34-40-76-130)124(158)145(90-96-51-25-14-26-52-96)82-70-116(151)136-107(59-33-39-75-129)123(157)144(89-95-49-23-13-24-50-95)81-69-115(150)135-106(58-32-38-74-128)122(156)143(88-94-47-21-12-22-48-94)80-68-114(149)134-105(57-31-37-73-127)121(155)142(87-93-45-19-11-20-46-93)79-67-113(148)133-104(56-30-36-72-126)120(154)141(86-92-43-17-10-18-44-92)78-66-112(147)132-103(55-29-35-71-125)119(153)140(77-65-111(131)146)85-91-41-15-9-16-42-91/h9-28,41-54,61-64,83-84,103-108H,5-8,29-40,55-60,65-82,85-90,125-130H2,1-4H3,(H7-,131,132,133,134,135,136,137,146,147,148,149,150,151,152)/p+1/t103-,104-,105-,106-,107-,108-/s2
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PubMed
n/an/a 15n/an/an/an/an/an/a



University of Copenhagen

Curated by ChEMBL


Assay Description
Antagonist activity at FPR2 in human peripheral blood polymorphonuclear neutrophils assessed as inhibition of WKYMVM-peptide induced ROS production p...


J Med Chem 60: 6991-6997 (2017)


Article DOI: 10.1021/acs.jmedchem.7b00489
BindingDB Entry DOI: 10.7270/Q2V40XFR
More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM50238900
PNG
(CHEMBL4090485)
Show SMILES CCN(CC)c1ccc2c(-c3ccccc3C(=O)N[C@@H](CCCCN)C(=O)N(CCC(=O)N[C@@H](CCCCN)C(=O)N(CCC(=O)N[C@@H](CCCCN)C(=O)N(CCC(=O)N[C@@H](CCCCN)C(=O)N(CCC(=O)N[C@@H](CCCCN)C(=O)N(CCC(N)=O)Cc3ccccc3)Cc3ccccc3)Cc3ccccc3)Cc3ccccc3)Cc3ccccc3)c3ccc(cc3oc2c1)=[N+](CC)CC
Show InChI InChI=1/C108H146N18O12/c1-5-120(6-2)84-53-55-88-95(72-84)138-96-73-85(121(7-3)8-4)54-56-89(96)102(88)86-46-24-25-47-87(86)103(132)119-94(52-30-35-66-113)108(137)126(78-83-44-22-13-23-45-83)71-61-101(131)118-93(51-29-34-65-112)107(136)125(77-82-42-20-12-21-43-82)70-60-100(130)117-92(50-28-33-64-111)106(135)124(76-81-40-18-11-19-41-81)69-59-99(129)116-91(49-27-32-63-110)105(134)123(75-80-38-16-10-17-39-80)68-58-98(128)115-90(48-26-31-62-109)104(133)122(67-57-97(114)127)74-79-36-14-9-15-37-79/h9-25,36-47,53-56,72-73,90-94H,5-8,26-35,48-52,57-71,74-78,109-113H2,1-4H3,(H6-,114,115,116,117,118,119,127,128,129,130,131,132)/p+1/t90-,91-,92-,93-,94-/s2
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PubMed
n/an/a 18n/an/an/an/an/an/a



University of Copenhagen

Curated by ChEMBL


Assay Description
Opioid receptor affinity against Opioid receptor kappa 1 by using the curve-fitting program LIGAND


J Med Chem 60: 6991-6997 (2017)


Article DOI: 10.1021/acs.jmedchem.7b00489
BindingDB Entry DOI: 10.7270/Q2V40XFR
More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM50238909
PNG
(CHEMBL4062611)
Show SMILES CCN(CC)c1ccc2c(-c3ccccc3C(=O)N[C@@H](CCCCN)C(=O)N(CCC(=O)N[C@@H](CCCCN)C(=O)N(CCC(=O)N[C@@H](CCCCN)C(=O)N(CCC(=O)N[C@@H](CCCCN)C(=O)N(CCC(=O)N[C@@H](CCCCN)C(=O)N(CCC(=O)N[C@@H](CCCCN)C(=O)N(CCC(N)=O)Cc3ccc(C)cc3)Cc3ccc(C)cc3)Cc3ccc(C)cc3)Cc3ccc(C)cc3)Cc3ccc(C)cc3)Cc3ccc(C)cc3)c3ccc(cc3oc2c1)=[N+](CC)CC
Show InChI InChI=1/C130H181N21O14/c1-11-144(12-2)103-61-63-107-115(83-103)165-116-84-104(145(13-3)14-4)62-64-108(116)123(107)105-29-15-16-30-106(105)124(158)143-114(36-22-28-76-136)130(164)151(90-102-59-47-96(10)48-60-102)82-70-122(157)142-113(35-21-27-75-135)129(163)150(89-101-57-45-95(9)46-58-101)81-69-121(156)141-112(34-20-26-74-134)128(162)149(88-100-55-43-94(8)44-56-100)80-68-120(155)140-111(33-19-25-73-133)127(161)148(87-99-53-41-93(7)42-54-99)79-67-119(154)139-110(32-18-24-72-132)126(160)147(86-98-51-39-92(6)40-52-98)78-66-118(153)138-109(31-17-23-71-131)125(159)146(77-65-117(137)152)85-97-49-37-91(5)38-50-97/h15-16,29-30,37-64,83-84,109-114H,11-14,17-28,31-36,65-82,85-90,131-136H2,1-10H3,(H7-,137,138,139,140,141,142,143,152,153,154,155,156,157,158)/p+1/t109-,110-,111-,112-,113-,114-/s2
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n/an/a 24n/an/an/an/an/an/a



University of Copenhagen

Curated by ChEMBL


Assay Description
Antagonist activity at FPR2 in human peripheral blood polymorphonuclear neutrophils assessed as inhibition of WKYMVM-peptide induced ROS production p...


J Med Chem 60: 6991-6997 (2017)


Article DOI: 10.1021/acs.jmedchem.7b00489
BindingDB Entry DOI: 10.7270/Q2V40XFR
More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM50238907
PNG
(CHEMBL4082093)
Show SMILES CCN(CC)c1ccc2c(-c3ccccc3C(=O)N[C@@H](CCCCN)C(=O)N(CCC(=O)N[C@@H](CCCCN)C(=O)N(CCC(=O)N[C@@H](CCCCN)C(=O)N(CCC(N)=O)Cc3ccccc3)Cc3ccccc3)Cc3ccccc3)c3ccc(cc3oc2c1)=[N+](CC)CC
Show InChI InChI=1/C76H100N12O8/c1-5-84(6-2)58-37-39-62-67(50-58)96-68-51-59(85(7-3)8-4)38-40-63(68)72(62)60-32-18-19-33-61(60)73(92)83-66(36-22-25-46-79)76(95)88(54-57-30-16-11-17-31-57)49-43-71(91)82-65(35-21-24-45-78)75(94)87(53-56-28-14-10-15-29-56)48-42-70(90)81-64(34-20-23-44-77)74(93)86(47-41-69(80)89)52-55-26-12-9-13-27-55/h9-19,26-33,37-40,50-51,64-66H,5-8,20-25,34-36,41-49,52-54,77-79H2,1-4H3,(H4-,80,81,82,83,89,90,91,92)/p+1/t64-,65-,66-/s2
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PubMed
n/an/a 28n/an/an/an/an/an/a



University of Copenhagen

Curated by ChEMBL


Assay Description
Antagonist activity at FPR2 in human peripheral blood polymorphonuclear neutrophils assessed as inhibition of WKYMVM-peptide induced ROS production p...


J Med Chem 60: 6991-6997 (2017)


Article DOI: 10.1021/acs.jmedchem.7b00489
BindingDB Entry DOI: 10.7270/Q2V40XFR
More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM50238894
PNG
(CHEMBL4062488)
Show SMILES CCN(CC)c1ccc2c(-c3ccccc3C(=O)N[C@@H](CCCCN)C(=O)N(CCC(=O)N[C@@H](CCCCN)C(=O)N(CCC(=O)N[C@@H](CCCCN)C(=O)N(CCC(=O)N[C@@H](CCCCN)C(=O)N(CCC(=O)N[C@@H](CCCCN)C(=O)N(CCC(=O)N[C@@H](CCCCN)C(=O)N(CCC(N)=O)[C@@H](C)c3ccccc3)[C@@H](C)c3ccccc3)[C@@H](C)c3ccccc3)[C@@H](C)c3ccccc3)[C@@H](C)c3ccccc3)[C@@H](C)c3ccccc3)c3ccc(cc3oc2c1)=[N+](CC)CC
Show InChI InChI=1/C130H181N21O14/c1-11-144(12-2)103-67-69-107-115(89-103)165-116-90-104(145(13-3)14-4)68-70-108(116)123(107)105-59-33-34-60-106(105)124(158)143-114(66-40-46-82-136)130(164)151(96(10)102-57-31-20-32-58-102)88-76-122(157)142-113(65-39-45-81-135)129(163)150(95(9)101-55-29-19-30-56-101)87-75-121(156)141-112(64-38-44-80-134)128(162)149(94(8)100-53-27-18-28-54-100)86-74-120(155)140-111(63-37-43-79-133)127(161)148(93(7)99-51-25-17-26-52-99)85-73-119(154)139-110(62-36-42-78-132)126(160)147(92(6)98-49-23-16-24-50-98)84-72-118(153)138-109(61-35-41-77-131)125(159)146(83-71-117(137)152)91(5)97-47-21-15-22-48-97/h15-34,47-60,67-70,89-96,109-114H,11-14,35-46,61-66,71-88,131-136H2,1-10H3,(H7-,137,138,139,140,141,142,143,152,153,154,155,156,157,158)/p+1/t91-,92-,93-,94-,95-,96-,109-,110-,111-,112-,113-,114-/s2
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n/an/a 34n/an/an/an/an/an/a



University of Copenhagen

Curated by ChEMBL


Assay Description
Antagonist activity at FPR2 in human peripheral blood polymorphonuclear neutrophils assessed as inhibition of WKYMVM-peptide induced ROS production p...


J Med Chem 60: 6991-6997 (2017)


Article DOI: 10.1021/acs.jmedchem.7b00489
BindingDB Entry DOI: 10.7270/Q2V40XFR
More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM50238901
PNG
(CHEMBL4072333)
Show SMILES CCN(CC)c1ccc2c(-c3ccccc3C(=O)N[C@@H](CCCCN)C(=O)N(CCC(=O)N[C@@H](CCCCN)C(=O)N(CCC(=O)N[C@@H](CCCCN)C(=O)N(CCC(=O)N[C@@H](CCCCN)C(=O)N(CCC(=O)N[C@@H](CCCCN)C(=O)N(CCC(=O)N[C@@H](CCCCN)C(=O)N(CCC(=O)N[C@@H](CCCCN)C(=O)N(CCC(N)=O)Cc3ccccc3)Cc3ccccc3)Cc3ccccc3)Cc3ccccc3)Cc3ccccc3)Cc3ccccc3)Cc3ccccc3)c3ccc(cc3oc2c1)=[N+](CC)CC
Show InChI InChI=1/C140H192N24O16/c1-5-156(6-2)110-69-71-114-123(94-110)180-124-95-111(157(7-3)8-4)70-72-115(124)132(114)112-60-30-31-61-113(112)133(172)155-122(68-38-45-86-147)140(179)164(102-109-58-28-15-29-59-109)93-79-131(171)154-121(67-37-44-85-146)139(178)163(101-108-56-26-14-27-57-108)92-78-130(170)153-120(66-36-43-84-145)138(177)162(100-107-54-24-13-25-55-107)91-77-129(169)152-119(65-35-42-83-144)137(176)161(99-106-52-22-12-23-53-106)90-76-128(168)151-118(64-34-41-82-143)136(175)160(98-105-50-20-11-21-51-105)89-75-127(167)150-117(63-33-40-81-142)135(174)159(97-104-48-18-10-19-49-104)88-74-126(166)149-116(62-32-39-80-141)134(173)158(87-73-125(148)165)96-103-46-16-9-17-47-103/h9-31,46-61,69-72,94-95,116-122H,5-8,32-45,62-68,73-93,96-102,141-147H2,1-4H3,(H8-,148,149,150,151,152,153,154,155,165,166,167,168,169,170,171,172)/p+1/t116-,117-,118-,119-,120-,121-,122-/s2
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n/an/a 35n/an/an/an/an/an/a



University of Copenhagen

Curated by ChEMBL


Assay Description
Opioid receptor mu 2 affinity against the receptor site model site 2(mu2)


J Med Chem 60: 6991-6997 (2017)


Article DOI: 10.1021/acs.jmedchem.7b00489
BindingDB Entry DOI: 10.7270/Q2V40XFR
More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM50238908
PNG
(CHEMBL4073052)
Show SMILES CCN(CC)c1ccc2c(-c3ccccc3C(=O)N[C@@H](CCCCN)C(=O)N(CCC(=O)N[C@@H](CCCCN)C(=O)N(CCC(=O)N[C@@H](CCCCN)C(=O)N(CCC(=O)N[C@@H](CCCCN)C(=O)N(CCC(=O)N[C@@H](CCCCN)C(=O)N(CCC(=O)N[C@@H](CCCCN)C(=O)N(CCC(=O)N[C@@H](CCCCN)C(=O)N(CCC(=O)N[C@@H](CCCCN)C(=O)N(CCC(N)=O)Cc3ccccc3)Cc3ccccc3)Cc3ccccc3)Cc3ccccc3)Cc3ccccc3)Cc3ccccc3)Cc3ccccc3)Cc3ccccc3)c3ccc(cc3oc2c1)=[N+](CC)CC
Show InChI InChI=1/C156H215N27O18/c1-5-174(6-2)123-77-79-127-137(105-123)201-138-106-124(175(7-3)8-4)78-80-128(138)147(127)125-67-33-34-68-126(125)148(192)173-136(76-42-50-96-164)156(200)183(114-122-65-31-16-32-66-122)104-88-146(191)172-135(75-41-49-95-163)155(199)182(113-121-63-29-15-30-64-121)103-87-145(190)171-134(74-40-48-94-162)154(198)181(112-120-61-27-14-28-62-120)102-86-144(189)170-133(73-39-47-93-161)153(197)180(111-119-59-25-13-26-60-119)101-85-143(188)169-132(72-38-46-92-160)152(196)179(110-118-57-23-12-24-58-118)100-84-142(187)168-131(71-37-45-91-159)151(195)178(109-117-55-21-11-22-56-117)99-83-141(186)167-130(70-36-44-90-158)150(194)177(108-116-53-19-10-20-54-116)98-82-140(185)166-129(69-35-43-89-157)149(193)176(97-81-139(165)184)107-115-51-17-9-18-52-115/h9-34,51-68,77-80,105-106,129-136H,5-8,35-50,69-76,81-104,107-114,157-164H2,1-4H3,(H9-,165,166,167,168,169,170,171,172,173,184,185,186,187,188,189,190,191,192)/p+1/t129-,130-,131-,132-,133-,134-,135-,136-/s2
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n/an/a 41n/an/an/an/an/an/a



University of Copenhagen

Curated by ChEMBL


Assay Description
Antagonist activity at FPR2 in human peripheral blood polymorphonuclear neutrophils assessed as inhibition of WKYMVM-peptide induced ROS production p...


J Med Chem 60: 6991-6997 (2017)


Article DOI: 10.1021/acs.jmedchem.7b00489
BindingDB Entry DOI: 10.7270/Q2V40XFR
More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM50098189
PNG
(CHEMBL3588930)
Show SMILES CCCCCCCCCCCCCCCC(=O)N[C@@H](CCCCN)C(=O)N(CCC(=O)N[C@@H](CCCCN)C(=O)N(CCC(=O)N[C@@H](CCCCN)C(=O)N(CCC(=O)N[C@@H](CCCCN)C(=O)N(CCC(=O)N[C@@H](CCCCN)C(=O)N(CCC(=O)N[C@@H](CCCCN)C(=O)N(CCC(N)=O)[C@@H](C)c1ccccc1)[C@@H](C)c1ccccc1)[C@@H](C)c1ccccc1)[C@@H](C)c1ccccc1)[C@@H](C)c1ccccc1)[C@@H](C)c1ccccc1
Show InChI InChI=1/C118H183N19O13/c1-8-9-10-11-12-13-14-15-16-17-18-19-38-69-107(139)126-100(63-39-45-76-119)114(146)133(89(3)95-53-28-21-29-54-95)83-71-109(141)128-102(65-41-47-78-121)116(148)135(91(5)97-57-32-23-33-58-97)85-73-111(143)130-104(67-43-49-80-123)118(150)137(93(7)99-61-36-25-37-62-99)87-75-112(144)131-105(68-44-50-81-124)117(149)136(92(6)98-59-34-24-35-60-98)86-74-110(142)129-103(66-42-48-79-122)115(147)134(90(4)96-55-30-22-31-56-96)84-72-108(140)127-101(64-40-46-77-120)113(145)132(82-70-106(125)138)88(2)94-51-26-20-27-52-94/h20-37,51-62,88-93,100-105H,8-19,38-50,63-87,119-124H2,1-7H3,(H2,125,138)(H,126,139)(H,127,140)(H,128,141)(H,129,142)(H,130,143)(H,131,144)/t88-,89-,90-,91-,92-,93-,100-,101-,102-,103-,104-,105-/s2
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n/an/a 41n/an/an/an/an/an/a



University of Copenhagen

Curated by ChEMBL


Assay Description
Antagonist activity at FPR2 in human peripheral blood polymorphonuclear neutrophils assessed as inhibition of WKYMVM-peptide induced ROS production p...


J Med Chem 60: 6991-6997 (2017)


Article DOI: 10.1021/acs.jmedchem.7b00489
BindingDB Entry DOI: 10.7270/Q2V40XFR
More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM50238896
PNG
(CHEMBL4072201)
Show SMILES CCN(CC)c1ccc2c(-c3ccccc3C(=O)N[C@@H](CCCCN)C(=O)N(CCC(=O)N[C@@H](CCCCN)C(=O)N(CCC(=O)N[C@@H](CCCCN)C(=O)N(CCC(=O)N[C@@H](CCCCN)C(=O)N(CCC(=O)N[C@@H](CCCCN)C(=O)N(CCC(=O)N[C@@H](CCCCN)C(=O)N(CCC(N)=O)[C@H](C)c3ccccc3)[C@H](C)c3ccccc3)[C@H](C)c3ccccc3)[C@H](C)c3ccccc3)[C@H](C)c3ccccc3)[C@H](C)c3ccccc3)c3ccc(cc3oc2c1)=[N+](CC)CC
Show InChI InChI=1/C130H181N21O14/c1-11-144(12-2)103-67-69-107-115(89-103)165-116-90-104(145(13-3)14-4)68-70-108(116)123(107)105-59-33-34-60-106(105)124(158)143-114(66-40-46-82-136)130(164)151(96(10)102-57-31-20-32-58-102)88-76-122(157)142-113(65-39-45-81-135)129(163)150(95(9)101-55-29-19-30-56-101)87-75-121(156)141-112(64-38-44-80-134)128(162)149(94(8)100-53-27-18-28-54-100)86-74-120(155)140-111(63-37-43-79-133)127(161)148(93(7)99-51-25-17-26-52-99)85-73-119(154)139-110(62-36-42-78-132)126(160)147(92(6)98-49-23-16-24-50-98)84-72-118(153)138-109(61-35-41-77-131)125(159)146(83-71-117(137)152)91(5)97-47-21-15-22-48-97/h15-34,47-60,67-70,89-96,109-114H,11-14,35-46,61-66,71-88,131-136H2,1-10H3,(H7-,137,138,139,140,141,142,143,152,153,154,155,156,157,158)/p+1/t91-,92-,93-,94-,95-,96-,109+,110+,111+,112+,113+,114+/s2
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n/an/a 44n/an/an/an/an/an/a



University of Copenhagen

Curated by ChEMBL


Assay Description
Antagonist activity at FPR2 in human peripheral blood polymorphonuclear neutrophils assessed as inhibition of WKYMVM-peptide induced ROS production p...


J Med Chem 60: 6991-6997 (2017)


Article DOI: 10.1021/acs.jmedchem.7b00489
BindingDB Entry DOI: 10.7270/Q2V40XFR
More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM50098189
PNG
(CHEMBL3588930)
Show SMILES CCCCCCCCCCCCCCCC(=O)N[C@@H](CCCCN)C(=O)N(CCC(=O)N[C@@H](CCCCN)C(=O)N(CCC(=O)N[C@@H](CCCCN)C(=O)N(CCC(=O)N[C@@H](CCCCN)C(=O)N(CCC(=O)N[C@@H](CCCCN)C(=O)N(CCC(=O)N[C@@H](CCCCN)C(=O)N(CCC(N)=O)[C@@H](C)c1ccccc1)[C@@H](C)c1ccccc1)[C@@H](C)c1ccccc1)[C@@H](C)c1ccccc1)[C@@H](C)c1ccccc1)[C@@H](C)c1ccccc1
Show InChI InChI=1/C118H183N19O13/c1-8-9-10-11-12-13-14-15-16-17-18-19-38-69-107(139)126-100(63-39-45-76-119)114(146)133(89(3)95-53-28-21-29-54-95)83-71-109(141)128-102(65-41-47-78-121)116(148)135(91(5)97-57-32-23-33-58-97)85-73-111(143)130-104(67-43-49-80-123)118(150)137(93(7)99-61-36-25-37-62-99)87-75-112(144)131-105(68-44-50-81-124)117(149)136(92(6)98-59-34-24-35-60-98)86-74-110(142)129-103(66-42-48-79-122)115(147)134(90(4)96-55-30-22-31-56-96)84-72-108(140)127-101(64-40-46-77-120)113(145)132(82-70-106(125)138)88(2)94-51-26-20-27-52-94/h20-37,51-62,88-93,100-105H,8-19,38-50,63-87,119-124H2,1-7H3,(H2,125,138)(H,126,139)(H,127,140)(H,128,141)(H,129,142)(H,130,143)(H,131,144)/t88-,89-,90-,91-,92-,93-,100-,101-,102-,103-,104-,105-/s2
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n/an/a 50n/an/an/an/an/an/a



University of Warsaw

Curated by ChEMBL


Assay Description
Allosteric antagonist activity against FPR2 (unknown origin)


Bioorg Med Chem 23: 4072-81 (2015)


Article DOI: 10.1016/j.bmc.2015.03.062
BindingDB Entry DOI: 10.7270/Q2KD20PR
More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM50238902
PNG
(CHEMBL4079416)
Show SMILES CCN(CC)c1ccc2c(-c3ccccc3C(=O)N[C@@H](CCCCN)C(=O)N(CCC(=O)N[C@@H](CCCCN)C(=O)N(CCC(=O)N[C@@H](CCCCN)C(=O)N(CCC(=O)N[C@@H](CCCCN)C(=O)N(CCC(=O)N[C@@H](CCCCN)C(=O)N(CCC(=O)N[C@@H](CCCCN)C(=O)N(CCC(N)=O)Cc3cc(F)c(F)c(F)c3)Cc3cc(F)c(F)c(F)c3)Cc3cc(F)c(F)c(F)c3)Cc3cc(F)c(F)c(F)c3)Cc3cc(F)c(F)c(F)c3)Cc3cc(F)c(F)c(F)c3)c3ccc(cc3oc2c1)=[N+](CC)CC
Show InChI InChI=1/C124H151F18N21O14/c1-5-156(6-2)79-31-33-83-103(65-79)177-104-66-80(157(7-3)8-4)32-34-84(104)111(83)81-23-9-10-24-82(81)118(170)155-102(30-16-22-46-148)124(176)163(72-78-63-95(135)117(142)96(136)64-78)52-40-110(169)154-101(29-15-21-45-147)123(175)162(71-77-61-93(133)116(141)94(134)62-77)51-39-109(168)153-100(28-14-20-44-146)122(174)161(70-76-59-91(131)115(140)92(132)60-76)50-38-108(167)152-99(27-13-19-43-145)121(173)160(69-75-57-89(129)114(139)90(130)58-75)49-37-107(166)151-98(26-12-18-42-144)120(172)159(68-74-55-87(127)113(138)88(128)56-74)48-36-106(165)150-97(25-11-17-41-143)119(171)158(47-35-105(149)164)67-73-53-85(125)112(137)86(126)54-73/h9-10,23-24,31-34,53-66,97-102H,5-8,11-22,25-30,35-52,67-72,143-148H2,1-4H3,(H7-,149,150,151,152,153,154,155,164,165,166,167,168,169,170)/p+1/t97-,98-,99-,100-,101-,102-/s2
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n/an/a 53n/an/an/an/an/an/a



University of Copenhagen

Curated by ChEMBL


Assay Description
Antagonist activity at FPR2 in human peripheral blood polymorphonuclear neutrophils assessed as inhibition of WKYMVM-peptide induced ROS production p...


J Med Chem 60: 6991-6997 (2017)


Article DOI: 10.1021/acs.jmedchem.7b00489
BindingDB Entry DOI: 10.7270/Q2V40XFR
More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM50238910
PNG
(CHEMBL4103322)
Show SMILES CCN(CC)c1ccc2c(-c3ccccc3C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc3ccccc3)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(O)=O)c3ccc(cc3oc2c1)=[N+](CC)CC
Show InChI InChI=1/C84H126N24O15/c1-9-107(10-2)51-31-33-55-65(45-51)123-66-46-52(108(11-3)12-4)32-34-56(66)70(55)53-25-16-17-26-54(53)72(112)99-60(35-37-67(86)109)76(116)100-59(29-21-41-95-83(90)91)75(115)104-63(43-48(5)6)78(118)105-64(44-50-23-14-13-15-24-50)79(119)101-61(36-38-68(87)110)77(117)106-71(49(7)8)80(120)102-57(27-18-19-39-85)73(113)97-47-69(111)98-58(28-20-40-94-82(88)89)74(114)103-62(81(121)122)30-22-42-96-84(92)93/h13-17,23-26,31-34,45-46,48-49,57-64,71H,9-12,18-22,27-30,35-44,47,85H2,1-8H3,(H26-,86,87,88,89,90,91,92,93,94,95,96,97,98,99,100,101,102,103,104,105,106,109,110,111,112,113,114,115,116,117,118,119,120,121,122)/p+1/t57-,58-,59-,60-,61-,62-,63-,64-,71-/s2
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n/an/a 60n/an/an/an/an/an/a



University of Copenhagen

Curated by ChEMBL


Assay Description
Opioid receptor affinity against the Opioid receptor delta 1 by using the curve-fitting program LIGAND


J Med Chem 60: 6991-6997 (2017)


Article DOI: 10.1021/acs.jmedchem.7b00489
BindingDB Entry DOI: 10.7270/Q2V40XFR
More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM50097999
PNG
(CHEMBL3590218)
Show SMILES CC(C)[C@H]1CNC(=O)C(=O)N1C[C@@H]1CCCN1C[C@@H](Cc1ccc2ccccc2c1)N1C[C@@H](Cc2ccc(O)cc2)N(CC2CCCCC2)C(=O)C1=O
Show InChI InChI=1/C43H55N5O5/c1-29(2)39-24-44-40(50)41(51)48(39)27-35-13-8-20-45(35)26-36(23-32-14-17-33-11-6-7-12-34(33)21-32)47-28-37(22-30-15-18-38(49)19-16-30)46(42(52)43(47)53)25-31-9-4-3-5-10-31/h6-7,11-12,14-19,21,29,31,35-37,39,49H,3-5,8-10,13,20,22-28H2,1-2H3,(H,44,50)/t35-,36+,37+,39+/s2
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n/an/a 80n/an/an/an/an/an/a



University of Warsaw

Curated by ChEMBL


Assay Description
Antagonist activity against FPR2 (unknown origin) pre-treated for 5 mins before addition of Wpep by Fluo4 florescence based intracellular Ca2+ mobili...


Bioorg Med Chem 23: 4072-81 (2015)


Article DOI: 10.1016/j.bmc.2015.03.062
BindingDB Entry DOI: 10.7270/Q2KD20PR
More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM50098001
PNG
(CHEMBL3590217)
Show SMILES CCCCOc1ccc(cc1)C(=O)NN1Cc2ccccc2NC1c1ccc(OC)cc1
Show InChI InChI=1/C26H29N3O3/c1-3-4-17-32-23-15-11-20(12-16-23)26(30)28-29-18-21-7-5-6-8-24(21)27-25(29)19-9-13-22(31-2)14-10-19/h5-16,25,27H,3-4,17-18H2,1-2H3,(H,28,30)
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n/an/a 90n/an/an/an/an/an/a



University of Warsaw

Curated by ChEMBL


Assay Description
Antagonist activity against human FPR2 expressed in rat RBL-2H3 cells pre-treated for 15 mins before addition of WKYMVm or C1 by intracellular Ca2+ m...


Bioorg Med Chem 23: 4072-81 (2015)


Article DOI: 10.1016/j.bmc.2015.03.062
BindingDB Entry DOI: 10.7270/Q2KD20PR
More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM50238904
PNG
(CHEMBL4082656)
Show SMILES CCN(CC)c1ccc2c(-c3ccccc3C(=O)N[C@@H](CCCCN)C(=O)N(CCC(=O)N[C@@H](CCCCN)C(=O)N(CCC(=O)N[C@@H](CCCCN)C(=O)N(CCC(=O)N[C@@H](CCCCN)C(=O)N(CCC(=O)N[C@@H](CCCCN)C(=O)N(CCC(=O)N[C@@H](CCCCN)C(=O)N(CCC(N)=O)Cc3ccc(cc3)C(F)(F)F)Cc3ccc(cc3)C(F)(F)F)Cc3ccc(cc3)C(F)(F)F)Cc3ccc(cc3)C(F)(F)F)Cc3ccc(cc3)C(F)(F)F)Cc3ccc(cc3)C(F)(F)F)c3ccc(cc3oc2c1)=[N+](CC)CC
Show InChI InChI=1/C130H163F18N21O14/c1-5-162(6-2)97-55-57-101-109(77-97)183-110-78-98(163(7-3)8-4)56-58-102(110)117(101)99-23-9-10-24-100(99)118(176)161-108(30-16-22-70-154)124(182)169(84-90-41-53-96(54-42-90)130(146,147)148)76-64-116(175)160-107(29-15-21-69-153)123(181)168(83-89-39-51-95(52-40-89)129(143,144)145)75-63-115(174)159-106(28-14-20-68-152)122(180)167(82-88-37-49-94(50-38-88)128(140,141)142)74-62-114(173)158-105(27-13-19-67-151)121(179)166(81-87-35-47-93(48-36-87)127(137,138)139)73-61-113(172)157-104(26-12-18-66-150)120(178)165(80-86-33-45-92(46-34-86)126(134,135)136)72-60-112(171)156-103(25-11-17-65-149)119(177)164(71-59-111(155)170)79-85-31-43-91(44-32-85)125(131,132)133/h9-10,23-24,31-58,77-78,103-108H,5-8,11-22,25-30,59-76,79-84,149-154H2,1-4H3,(H7-,155,156,157,158,159,160,161,170,171,172,173,174,175,176)/p+1/t103-,104-,105-,106-,107-,108-/s2
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n/an/a 94n/an/an/an/an/an/a



University of Copenhagen

Curated by ChEMBL


Assay Description
Antagonist activity at FPR2 in human peripheral blood polymorphonuclear neutrophils assessed as inhibition of WKYMVM-peptide induced ROS production p...


J Med Chem 60: 6991-6997 (2017)


Article DOI: 10.1021/acs.jmedchem.7b00489
BindingDB Entry DOI: 10.7270/Q2V40XFR
More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM50098007
PNG
(CHEMBL3590216)
Show SMILES CCCCOc1ccc(cc1)C(=O)NN1Cc2ccccc2NC1c1ccc(C)cc1
Show InChI InChI=1/C26H29N3O2/c1-3-4-17-31-23-15-13-21(14-16-23)26(30)28-29-18-22-7-5-6-8-24(22)27-25(29)20-11-9-19(2)10-12-20/h5-16,25,27H,3-4,17-18H2,1-2H3,(H,28,30)
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n/an/a 170n/an/an/an/an/an/a



University of Warsaw

Curated by ChEMBL


Assay Description
Antagonist activity against human FPR2 expressed in rat RBL-2H3 cells pre-treated for 15 mins before addition of WKYMVm or C1 by intracellular Ca2+ m...


Bioorg Med Chem 23: 4072-81 (2015)


Article DOI: 10.1016/j.bmc.2015.03.062
BindingDB Entry DOI: 10.7270/Q2KD20PR
More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM50238898
PNG
(CHEMBL4094101)
Show SMILES CCN(CC)c1ccc2c(-c3ccccc3C(=O)N[C@@H](CCCCN)C(=O)N(CCC(=O)N[C@@H](CCCCN)C(=O)N(CCC(N)=O)Cc3ccccc3)Cc3ccccc3)c3ccc(cc3oc2c1)=[N+](CC)CC
Show InChI InChI=1/C60H77N9O6/c1-5-66(6-2)45-29-31-49-53(39-45)75-54-40-46(67(7-3)8-4)30-32-50(54)57(49)47-25-15-16-26-48(47)58(72)65-52(28-18-20-36-62)60(74)69(42-44-23-13-10-14-24-44)38-34-56(71)64-51(27-17-19-35-61)59(73)68(37-33-55(63)70)41-43-21-11-9-12-22-43/h9-16,21-26,29-32,39-40,51-52H,5-8,17-20,27-28,33-38,41-42,61-62H2,1-4H3,(H3-,63,64,65,70,71,72)/p+1/t51-,52-/s2
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n/an/a 273n/an/an/an/an/an/a



University of Copenhagen

Curated by ChEMBL


Assay Description
Antagonist activity at FPR2 in human peripheral blood polymorphonuclear neutrophils assessed as inhibition of WKYMVM-peptide induced ROS production p...


J Med Chem 60: 6991-6997 (2017)


Article DOI: 10.1021/acs.jmedchem.7b00489
BindingDB Entry DOI: 10.7270/Q2V40XFR
More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM50238897
PNG
(CHEMBL4067361)
Show SMILES CCN(CC)c1ccc2c(-c3ccccc3C(=O)N[C@@H](CCCCN)C(=O)N(CCC(N)=O)Cc3ccccc3)c3ccc(cc3oc2c1)=[N+](CC)CC
Show InChI InChI=1/C44H54N6O4/c1-5-48(6-2)32-21-23-36-39(28-32)54-40-29-33(49(7-3)8-4)22-24-37(40)42(36)34-18-12-13-19-35(34)43(52)47-38(20-14-15-26-45)44(53)50(27-25-41(46)51)30-31-16-10-9-11-17-31/h9-13,16-19,21-24,28-29,38H,5-8,14-15,20,25-27,30,45H2,1-4H3,(H2-,46,47,51,52)/p+1/t38-/s2
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n/an/a 759n/an/an/an/an/an/a



University of Copenhagen

Curated by ChEMBL


Assay Description
Antagonist activity at FPR2 in human peripheral blood polymorphonuclear neutrophils assessed as inhibition of WKYMVM-peptide induced ROS production p...


J Med Chem 60: 6991-6997 (2017)


Article DOI: 10.1021/acs.jmedchem.7b00489
BindingDB Entry DOI: 10.7270/Q2V40XFR
More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM50238905
PNG
(CHEMBL4084411)
Show SMILES CCCCCCCCCCCCCCCC(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(N)=O
Show InChI InChI=1/C72H129N23O13/c1-6-7-8-9-10-11-12-13-14-15-16-17-21-33-58(98)87-52(34-36-56(74)96)65(104)90-51(32-26-41-85-72(81)82)64(103)93-54(42-45(2)3)67(106)94-55(43-47-27-19-18-20-28-47)68(107)91-53(35-37-57(75)97)66(105)95-60(46(4)5)69(108)92-49(29-22-23-38-73)62(101)86-44-59(99)88-50(31-25-40-84-71(79)80)63(102)89-48(61(76)100)30-24-39-83-70(77)78/h18-20,27-28,45-46,48-55,60H,6-17,21-26,29-44,73H2,1-5H3,(H2,74,96)(H2,75,97)(H2,76,100)(H,86,101)(H,87,98)(H,88,99)(H,89,102)(H,90,104)(H,91,107)(H,92,108)(H,93,103)(H,94,106)(H,95,105)(H4,77,78,83)(H4,79,80,84)(H4,81,82,85)/t48-,49-,50-,51-,52-,53-,54-,55-,60-/s2
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n/an/a 900n/an/an/an/an/an/a



University of Copenhagen

Curated by ChEMBL


Assay Description
Antagonist activity at FPR2 in human peripheral blood polymorphonuclear neutrophils assessed as inhibition of WKYMVM-peptide induced ROS production p...


J Med Chem 60: 6991-6997 (2017)


Article DOI: 10.1021/acs.jmedchem.7b00489
BindingDB Entry DOI: 10.7270/Q2V40XFR
More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM50238895
PNG
(CHEMBL4105404)
Show SMILES CCCCCCCCCCCCCCCC(=O)N[C@H](CCC(N)=O)C(=O)N[C@H](CCCNC(N)=N)C(=O)N[C@H](CC(C)C)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@H](CCC(N)=O)C(=O)N[C@H](C(C)C)C(=O)N[C@H](CCCCN)C(=O)NCC(=O)N[C@H](CCCNC(N)=N)C(=O)N[C@H](CCCNC(N)=N)C(N)=O
Show InChI InChI=1/C72H129N23O13/c1-6-7-8-9-10-11-12-13-14-15-16-17-21-33-58(98)87-52(34-36-56(74)96)65(104)90-51(32-26-41-85-72(81)82)64(103)93-54(42-45(2)3)67(106)94-55(43-47-27-19-18-20-28-47)68(107)91-53(35-37-57(75)97)66(105)95-60(46(4)5)69(108)92-49(29-22-23-38-73)62(101)86-44-59(99)88-50(31-25-40-84-71(79)80)63(102)89-48(61(76)100)30-24-39-83-70(77)78/h18-20,27-28,45-46,48-55,60H,6-17,21-26,29-44,73H2,1-5H3,(H2,74,96)(H2,75,97)(H2,76,100)(H,86,101)(H,87,98)(H,88,99)(H,89,102)(H,90,104)(H,91,107)(H,92,108)(H,93,103)(H,94,106)(H,95,105)(H4,77,78,83)(H4,79,80,84)(H4,81,82,85)/t48-,49-,50-,51-,52-,53-,54-,55-,60-/s2
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n/an/a 1.12E+3n/an/an/an/an/an/a



University of Copenhagen

Curated by ChEMBL


Assay Description
Antagonist activity at FPR2 in human peripheral blood polymorphonuclear neutrophils assessed as inhibition of WKYMVM-peptide induced ROS production p...


J Med Chem 60: 6991-6997 (2017)


Article DOI: 10.1021/acs.jmedchem.7b00489
BindingDB Entry DOI: 10.7270/Q2V40XFR
More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM40750
PNG
(N-(5-imidazo[1,2-a]pyrimidin-2-yl-2-methoxy-phenyl...)
Show SMILES COc1ccc(cc1NC(=O)C(C)C)-c1cn2cccnc2n1
Show InChI InChI=1S/C17H18N4O2/c1-11(2)16(22)19-13-9-12(5-6-15(13)23-3)14-10-21-8-4-7-18-17(21)20-14/h4-11H,1-3H3,(H,19,22)
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n/an/a 3.60E+3n/an/an/an/an/an/a



NMMLSC

Curated by PubChem BioAssay


Assay Description
University of New Mexico Assay Overview: Assay Support: NIH 1R03MH076381-01 Assay for Formylpeptide Receptor Family Ligands PI: Bruce S. Edwards, Ph...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q2NP22V6
More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM40755
PNG
(2-(4-chlorophenyl)-N-(5-imidazo[1,2-a]pyrimidin-2-...)
Show SMILES COc1ccc(cc1NC(=O)Cc1ccc(Cl)cc1)-c1cn2cccnc2n1
Show InChI InChI=1S/C21H17ClN4O2/c1-28-19-8-5-15(18-13-26-10-2-9-23-21(26)25-18)12-17(19)24-20(27)11-14-3-6-16(22)7-4-14/h2-10,12-13H,11H2,1H3,(H,24,27)
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n/an/a 5.30E+3n/an/an/an/an/an/a



NMMLSC

Curated by PubChem BioAssay


Assay Description
University of New Mexico Assay Overview: Assay Support: NIH 1R03MH076381-01 Assay for Formylpeptide Receptor Family Ligands PI: Bruce S. Edwards, Ph...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q2NP22V6
More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM50098046
PNG
(CHEMBL3590215)
Show SMILES CCCCOc1ccc(cc1)C(=O)NN1Cc2ccccc2NC1c1ccc(O)cc1
Show InChI InChI=1/C25H27N3O3/c1-2-3-16-31-22-14-10-19(11-15-22)25(30)27-28-17-20-6-4-5-7-23(20)26-24(28)18-8-12-21(29)13-9-18/h4-15,24,26,29H,2-3,16-17H2,1H3,(H,27,30)
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n/an/a 6.65E+3n/an/an/an/an/an/a



University of Warsaw

Curated by ChEMBL


Assay Description
Antagonist activity against human FPR2 expressed in rat RBL-2H3 cells pre-treated for 15 mins before addition of WKYMVm or C1 by intracellular Ca2+ m...


Bioorg Med Chem 23: 4072-81 (2015)


Article DOI: 10.1016/j.bmc.2015.03.062
BindingDB Entry DOI: 10.7270/Q2KD20PR
More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM37690
PNG
(MLS000045944 | N-(5-imidazo[1,2-a]pyrimidin-2-yl-2...)
Show SMILES COc1ccc(cc1NC(=O)C1CC1)-c1cn2cccnc2n1
Show InChI InChI=1S/C17H16N4O2/c1-23-15-6-5-12(9-13(15)19-16(22)11-3-4-11)14-10-21-8-2-7-18-17(21)20-14/h2,5-11H,3-4H2,1H3,(H,19,22)
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n/an/a 6.70E+3n/an/an/an/an/an/a



NMMLSC

Curated by PubChem BioAssay


Assay Description
University of New Mexico Assay Overview: Assay Support: NIH 1R03MH076381-01 Assay for Formylpeptide Receptor Family Ligands PI: Bruce S. Edwards, Ph...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q2NP22V6
More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM37792
PNG
(MLS000118373 | SMR000095315 | cid_5308727)
Show SMILES CN1CCN(CC1)c1cc(NCCOC(C)=O)c2C(=O)c3ccccc3-c3onc1c23
Show InChI InChI=1S/C23H24N4O4/c1-14(28)30-12-7-24-17-13-18(27-10-8-26(2)9-11-27)21-20-19(17)22(29)15-5-3-4-6-16(15)23(20)31-25-21/h3-6,13,24H,7-12H2,1-2H3
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n/an/a 6.90E+3n/an/an/an/an/an/a



NMMLSC

Curated by PubChem BioAssay


Assay Description
University of New Mexico Assay Overview Assay Support: NIH 1R03MH076381-01 Assay for Formylpeptide Receptor Family Ligands PI: Bruce S. Edwards, Ph....


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q2DF6PMF
More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM37690
PNG
(MLS000045944 | N-(5-imidazo[1,2-a]pyrimidin-2-yl-2...)
Show SMILES COc1ccc(cc1NC(=O)C1CC1)-c1cn2cccnc2n1
Show InChI InChI=1S/C17H16N4O2/c1-23-15-6-5-12(9-13(15)19-16(22)11-3-4-11)14-10-21-8-2-7-18-17(21)20-14/h2,5-11H,3-4H2,1H3,(H,19,22)
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n/an/a 7.60E+3n/an/an/an/an/an/a



NMMLSC

Curated by PubChem BioAssay


Assay Description
University of New Mexico Assay Overview Assay Support: NIH 1R03MH076381-01 Assay for Formylpeptide Receptor Family Ligands PI: Bruce S. Edwards, Ph....


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q2DF6PMF
More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM40754
PNG
(N-(5-imidazo[1,2-a]pyrimidin-2-yl-2-methoxy-phenyl...)
Show SMILES COc1ccc(CC(=O)Nc2cc(ccc2OC)-c2cn3cccnc3n2)cc1
Show InChI InChI=1S/C22H20N4O3/c1-28-17-7-4-15(5-8-17)12-21(27)24-18-13-16(6-9-20(18)29-2)19-14-26-11-3-10-23-22(26)25-19/h3-11,13-14H,12H2,1-2H3,(H,24,27)
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n/an/a 9.90E+3n/an/an/an/an/an/a



NMMLSC

Curated by PubChem BioAssay


Assay Description
University of New Mexico Assay Overview: Assay Support: NIH 1R03MH076381-01 Assay for Formylpeptide Receptor Family Ligands PI: Bruce S. Edwards, Ph...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q2NP22V6
More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM40749
PNG
(N-(5-imidazo[1,2-a]pyrimidin-2-yl-2-methoxy-phenyl...)
Show SMILES CCC(=O)Nc1cc(ccc1OC)-c1cn2cccnc2n1
Show InChI InChI=1S/C16H16N4O2/c1-3-15(21)18-12-9-11(5-6-14(12)22-2)13-10-20-8-4-7-17-16(20)19-13/h4-10H,3H2,1-2H3,(H,18,21)
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n/an/a 1.07E+4n/an/an/an/an/an/a



NMMLSC

Curated by PubChem BioAssay


Assay Description
University of New Mexico Assay Overview: Assay Support: NIH 1R03MH076381-01 Assay for Formylpeptide Receptor Family Ligands PI: Bruce S. Edwards, Ph...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q2NP22V6
More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM37712
PNG
(4-{[3-(1,4-dioxa-8-azaspiro[4.5]dec-8-yl)-6-oxo-6H...)
Show SMILES OC(=O)CCCNc1cc(N2CCC3(CC2)OCCO3)c2noc3-c4ccccc4C(=O)c1c23
Show InChI InChI=1S/C25H25N3O6/c29-19(30)6-3-9-26-17-14-18(28-10-7-25(8-11-28)32-12-13-33-25)22-21-20(17)23(31)15-4-1-2-5-16(15)24(21)34-27-22/h1-2,4-5,14,26H,3,6-13H2,(H,29,30)
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n/an/a 1.09E+4n/an/an/an/an/an/a



NMMLSC

Curated by PubChem BioAssay


Assay Description
University of New Mexico Assay Overview Assay Support: NIH 1R03MH076381-01 Assay for Formylpeptide Receptor Family Ligands PI: Bruce S. Edwards, Ph....


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q2DF6PMF
More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM37745
PNG
(2-[[4-methyl-5-[[(3,4,5-triethoxybenzoyl)amino]met...)
Show SMILES CCOC(=O)CSc1nnc(CNC(=O)c2cc(OCC)c(OCC)c(OCC)c2)n1C
Show InChI InChI=1S/C21H30N4O6S/c1-6-28-15-10-14(11-16(29-7-2)19(15)31-9-4)20(27)22-12-17-23-24-21(25(17)5)32-13-18(26)30-8-3/h10-11H,6-9,12-13H2,1-5H3,(H,22,27)
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n/an/a 1.12E+4n/an/an/an/an/an/a



NMMLSC

Curated by PubChem BioAssay


Assay Description
University of New Mexico Assay Overview Assay Support: NIH 1R03MH076381-01 Assay for Formylpeptide Receptor Family Ligands PI: Bruce S. Edwards, Ph....


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q2DF6PMF
More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM37686
PNG
(2-(4-benzylpiperazin-1-yl)-4-(3,4-dimethoxyphenyl)...)
Show SMILES COc1ccc(cc1OC)-c1cc(nc(n1)N1CCN(Cc2ccccc2)CC1)C(F)(F)F
Show InChI InChI=1S/C24H25F3N4O2/c1-32-20-9-8-18(14-21(20)33-2)19-15-22(24(25,26)27)29-23(28-19)31-12-10-30(11-13-31)16-17-6-4-3-5-7-17/h3-9,14-15H,10-13,16H2,1-2H3
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n/an/a 1.21E+4n/an/an/an/an/an/a



NMMLSC

Curated by PubChem BioAssay


Assay Description
University of New Mexico Assay Overview Assay Support: NIH 1R03MH076381-01 Assay for Formylpeptide Receptor Family Ligands PI: Bruce S. Edwards, Ph....


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q2DF6PMF
More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM37692
PNG
((2-aminophenyl)-(4-aminophenyl)amine | 2-N-(4-amin...)
Show SMILES Nc1ccc(Nc2ccccc2N)cc1
Show InChI InChI=1S/C12H13N3/c13-9-5-7-10(8-6-9)15-12-4-2-1-3-11(12)14/h1-8,15H,13-14H2
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n/an/a 1.50E+4n/an/an/an/an/an/a



NMMLSC

Curated by PubChem BioAssay


Assay Description
University of New Mexico Assay Overview Assay Support: NIH 1R03MH076381-01 Assay for Formylpeptide Receptor Family Ligands PI: Bruce S. Edwards, Ph....


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q2DF6PMF
More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM37686
PNG
(2-(4-benzylpiperazin-1-yl)-4-(3,4-dimethoxyphenyl)...)
Show SMILES COc1ccc(cc1OC)-c1cc(nc(n1)N1CCN(Cc2ccccc2)CC1)C(F)(F)F
Show InChI InChI=1S/C24H25F3N4O2/c1-32-20-9-8-18(14-21(20)33-2)19-15-22(24(25,26)27)29-23(28-19)31-12-10-30(11-13-31)16-17-6-4-3-5-7-17/h3-9,14-15H,10-13,16H2,1-2H3
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n/an/a 1.65E+4n/an/an/an/an/an/a



NMMLSC

Curated by PubChem BioAssay


Assay Description
University of New Mexico Assay Overview: Assay Support: NIH 1R03MH076381-01 Assay for Formylpeptide Receptor Family Ligands PI: Bruce S. Edwards, Ph...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q2NP22V6
More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM37721
PNG
(2-(3-chlorophenyl)-4-N-methyltriazole-4,5-diamine ...)
Show SMILES CNc1nn(nc1N)-c1cccc(Cl)c1
Show InChI InChI=1S/C9H10ClN5/c1-12-9-8(11)13-15(14-9)7-4-2-3-6(10)5-7/h2-5H,1H3,(H2,11,13)(H,12,14)
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n/an/a 1.82E+4n/an/an/an/an/an/a



NMMLSC

Curated by PubChem BioAssay


Assay Description
University of New Mexico Assay Overview Assay Support: NIH 1R03MH076381-01 Assay for Formylpeptide Receptor Family Ligands PI: Bruce S. Edwards, Ph....


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q2DF6PMF
More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM37719
PNG
(2-[[4-methyl-5-[[(3,4,5-triethoxybenzoyl)amino]met...)
Show SMILES CCOc1cc(cc(OCC)c1OCC)C(=O)NCc1nnc(SCC(=O)OC)n1C
Show InChI InChI=1S/C20H28N4O6S/c1-6-28-14-9-13(10-15(29-7-2)18(14)30-8-3)19(26)21-11-16-22-23-20(24(16)4)31-12-17(25)27-5/h9-10H,6-8,11-12H2,1-5H3,(H,21,26)
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n/an/a 1.85E+4n/an/an/an/an/an/a



NMMLSC

Curated by PubChem BioAssay


Assay Description
University of New Mexico Assay Overview Assay Support: NIH 1R03MH076381-01 Assay for Formylpeptide Receptor Family Ligands PI: Bruce S. Edwards, Ph....


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q2DF6PMF
More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM37754
PNG
(MLS000045942 | N-(5-imidazo[1,2-a]pyrimidin-2-yl-2...)
Show SMILES CCCC(=O)Nc1cc(ccc1OC)-c1cn2cccnc2n1
Show InChI InChI=1S/C17H18N4O2/c1-3-5-16(22)19-13-10-12(6-7-15(13)23-2)14-11-21-9-4-8-18-17(21)20-14/h4,6-11H,3,5H2,1-2H3,(H,19,22)
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n/an/a 2.28E+4n/an/an/an/an/an/a



NMMLSC

Curated by PubChem BioAssay


Assay Description
University of New Mexico Assay Overview Assay Support: NIH 1R03MH076381-01 Assay for Formylpeptide Receptor Family Ligands PI: Bruce S. Edwards, Ph....


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q2DF6PMF
More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM32017
PNG
((7S,9S)-7-[(2R,4S,5S,6S)-4-azanyl-6-methyl-5-oxida...)
Show SMILES COc1cccc2C(=O)c3c(O)c4C[C@](O)(C[C@H](O[C@H]5C[C@H](N)[C@H](O)[C@H](C)O5)c4c(O)c3C(=O)c12)C(C)=O
Show InChI InChI=1S/C27H29NO10/c1-10-22(30)14(28)7-17(37-10)38-16-9-27(35,11(2)29)8-13-19(16)26(34)21-20(24(13)32)23(31)12-5-4-6-15(36-3)18(12)25(21)33/h4-6,10,14,16-17,22,30,32,34-35H,7-9,28H2,1-3H3/t10-,14-,16-,17-,22+,27-/m0/s1
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n/an/a 2.51E+4n/an/an/an/an/an/a



NMMLSC

Curated by PubChem BioAssay


Assay Description
University of New Mexico Assay Overview Assay Support: NIH 1R03MH076381-01 Assay for Formylpeptide Receptor Family Ligands PI: Bruce S. Edwards, Ph....


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q2DF6PMF
More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM37827
PNG
(2-methyl-5-(4-nitrophenyl)-3-phenyl-1H-pyrazolo[1,...)
Show SMILES Cc1[nH]n2c(nc(cc2=O)-c2ccc(cc2)[N+]([O-])=O)c1-c1ccccc1
Show InChI InChI=1S/C19H14N4O3/c1-12-18(14-5-3-2-4-6-14)19-20-16(11-17(24)22(19)21-12)13-7-9-15(10-8-13)23(25)26/h2-11,21H,1H3
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n/an/a 3.17E+4n/an/an/an/an/an/a



NMMLSC

Curated by PubChem BioAssay


Assay Description
University of New Mexico Assay Overview Assay Support: NIH 1R03MH076381-01 Assay for Formylpeptide Receptor Family Ligands PI: Bruce S. Edwards, Ph....


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q2DF6PMF
More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM40747
PNG
(2-(4-benzhydrylpiperazin-1-yl)-4-(3,4-dimethoxyphe...)
Show SMILES COc1ccc(cc1OC)-c1cc(nc(n1)N1CCN(CC1)C(c1ccccc1)c1ccccc1)C(F)(F)F
Show InChI InChI=1S/C30H29F3N4O2/c1-38-25-14-13-23(19-26(25)39-2)24-20-27(30(31,32)33)35-29(34-24)37-17-15-36(16-18-37)28(21-9-5-3-6-10-21)22-11-7-4-8-12-22/h3-14,19-20,28H,15-18H2,1-2H3
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n/an/a>4.16E+4n/an/an/an/an/an/a



NMMLSC

Curated by PubChem BioAssay


Assay Description
University of New Mexico Assay Overview: Assay Support: NIH 1R03MH076381-01 Assay for Formylpeptide Receptor Family Ligands PI: Bruce S. Edwards, Ph...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q2NP22V6
More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM37746
PNG
(MLS000045943 | N-(5-imidazo[1,2-a]pyrimidin-2-yl-2...)
Show SMILES COc1ccc(cc1NC(=O)CC(C)C)-c1cn2cccnc2n1
Show InChI InChI=1S/C18H20N4O2/c1-12(2)9-17(23)20-14-10-13(5-6-16(14)24-3)15-11-22-8-4-7-19-18(22)21-15/h4-8,10-12H,9H2,1-3H3,(H,20,23)
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n/an/a 4.50E+4n/an/an/an/an/an/a



NMMLSC

Curated by PubChem BioAssay


Assay Description
University of New Mexico Assay Overview Assay Support: NIH 1R03MH076381-01 Assay for Formylpeptide Receptor Family Ligands PI: Bruce S. Edwards, Ph....


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q2DF6PMF
More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM37752
PNG
(MLS000086406 | N-{3-[4-(ethoxycarbonyl)piperazin-1...)
Show SMILES CCOC(=O)N1CCN(CC1)c1cc(NCCC(O)=O)c2C(=O)c3ccccc3-c3onc1c23
Show InChI InChI=1S/C24H24N4O6/c1-2-33-24(32)28-11-9-27(10-12-28)17-13-16(25-8-7-18(29)30)19-20-21(17)26-34-23(20)15-6-4-3-5-14(15)22(19)31/h3-6,13,25H,2,7-12H2,1H3,(H,29,30)
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n/an/a 4.99E+4n/an/an/an/an/an/a



NMMLSC

Curated by PubChem BioAssay


Assay Description
University of New Mexico Assay Overview Assay Support: NIH 1R03MH076381-01 Assay for Formylpeptide Receptor Family Ligands PI: Bruce S. Edwards, Ph....


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q2DF6PMF
More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM37701
PNG
(4-(3,4-dimethoxyphenyl)-2-(4-phenyl-1-piperazinyl)...)
Show SMILES COc1ccc(cc1OC)-c1cc(nc(n1)N1CCN(CC1)c1ccccc1)C(F)(F)F
Show InChI InChI=1S/C23H23F3N4O2/c1-31-19-9-8-16(14-20(19)32-2)18-15-21(23(24,25)26)28-22(27-18)30-12-10-29(11-13-30)17-6-4-3-5-7-17/h3-9,14-15H,10-13H2,1-2H3
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n/an/a>5.00E+4n/an/an/an/an/an/a



NMMLSC

Curated by PubChem BioAssay


Assay Description
University of New Mexico Assay Overview: Assay Support: NIH 1R03MH076381-01 Assay for Formylpeptide Receptor Family Ligands PI: Bruce S. Edwards, Ph...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q2NP22V6
More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM40748
PNG
(4-[4-(3,4-dimethoxyphenyl)-6-(trifluoromethyl)-2-p...)
Show SMILES CCOC(=O)N1CCN(CC1)c1nc(cc(n1)C(F)(F)F)-c1ccc(OC)c(OC)c1
Show InChI InChI=1S/C20H23F3N4O4/c1-4-31-19(28)27-9-7-26(8-10-27)18-24-14(12-17(25-18)20(21,22)23)13-5-6-15(29-2)16(11-13)30-3/h5-6,11-12H,4,7-10H2,1-3H3
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n/an/a>5.05E+4n/an/an/an/an/an/a



NMMLSC

Curated by PubChem BioAssay


Assay Description
University of New Mexico Assay Overview: Assay Support: NIH 1R03MH076381-01 Assay for Formylpeptide Receptor Family Ligands PI: Bruce S. Edwards, Ph...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q2NP22V6
More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM40745
PNG
(2-[4-(2-methoxyphenyl)-1-piperazinyl]-4-phenyl-6-(...)
Show SMILES COc1ccccc1N1CCN(CC1)c1nc(cc(n1)C(F)(F)F)-c1ccccc1
Show InChI InChI=1S/C22H21F3N4O/c1-30-19-10-6-5-9-18(19)28-11-13-29(14-12-28)21-26-17(16-7-3-2-4-8-16)15-20(27-21)22(23,24)25/h2-10,15H,11-14H2,1H3
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n/an/a>5.36E+4n/an/an/an/an/an/a



NMMLSC

Curated by PubChem BioAssay


Assay Description
University of New Mexico Assay Overview: Assay Support: NIH 1R03MH076381-01 Assay for Formylpeptide Receptor Family Ligands PI: Bruce S. Edwards, Ph...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q2NP22V6
More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM40753
PNG
(2-chloranyl-6-fluoranyl-N-(5-imidazo[1,2-a]pyrimid...)
Show SMILES COc1ccc(cc1NC(=O)c1c(F)cccc1Cl)-c1cn2cccnc2n1
Show InChI InChI=1S/C20H14ClFN4O2/c1-28-17-7-6-12(16-11-26-9-3-8-23-20(26)25-16)10-15(17)24-19(27)18-13(21)4-2-5-14(18)22/h2-11H,1H3,(H,24,27)
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n/an/a>5.60E+4n/an/an/an/an/an/a



NMMLSC

Curated by PubChem BioAssay


Assay Description
University of New Mexico Assay Overview: Assay Support: NIH 1R03MH076381-01 Assay for Formylpeptide Receptor Family Ligands PI: Bruce S. Edwards, Ph...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q2NP22V6
More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM40746
PNG
(2,2,2-trifluoro-1-[4-(4-phenyl-2-quinazolinyl)-1-p...)
Show SMILES FC(F)(F)C(=O)N1CCN(CC1)c1nc(-c2ccccc2)c2ccccc2n1
Show InChI InChI=1S/C20H17F3N4O/c21-20(22,23)18(28)26-10-12-27(13-11-26)19-24-16-9-5-4-8-15(16)17(25-19)14-6-2-1-3-7-14/h1-9H,10-13H2
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n/an/a>5.75E+4n/an/an/an/an/an/a



NMMLSC

Curated by PubChem BioAssay


Assay Description
University of New Mexico Assay Overview: Assay Support: NIH 1R03MH076381-01 Assay for Formylpeptide Receptor Family Ligands PI: Bruce S. Edwards, Ph...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q2NP22V6
More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM40752
PNG
(2,6-bis(fluoranyl)-N-(5-imidazo[1,2-a]pyrimidin-2-...)
Show SMILES COc1ccc(cc1NC(=O)c1c(F)cccc1F)-c1cn2cccnc2n1
Show InChI InChI=1S/C20H14F2N4O2/c1-28-17-7-6-12(16-11-26-9-3-8-23-20(26)25-16)10-15(17)24-19(27)18-13(21)4-2-5-14(18)22/h2-11H,1H3,(H,24,27)
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n/an/a>5.84E+4n/an/an/an/an/an/a



NMMLSC

Curated by PubChem BioAssay


Assay Description
University of New Mexico Assay Overview: Assay Support: NIH 1R03MH076381-01 Assay for Formylpeptide Receptor Family Ligands PI: Bruce S. Edwards, Ph...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q2NP22V6
More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM40751
PNG
(2-cyclohexyl-N-(5-imidazo[1,2-a]pyrimidin-2-yl-2-m...)
Show SMILES COc1ccc(cc1NC(=O)CC1CCCCC1)-c1cn2cccnc2n1
Show InChI InChI=1S/C21H24N4O2/c1-27-19-9-8-16(18-14-25-11-5-10-22-21(25)24-18)13-17(19)23-20(26)12-15-6-3-2-4-7-15/h5,8-11,13-15H,2-4,6-7,12H2,1H3,(H,23,26)
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n/an/a>6.10E+4n/an/an/an/an/an/a



NMMLSC

Curated by PubChem BioAssay


Assay Description
University of New Mexico Assay Overview: Assay Support: NIH 1R03MH076381-01 Assay for Formylpeptide Receptor Family Ligands PI: Bruce S. Edwards, Ph...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q2NP22V6
More data for this
Ligand-Target Pair
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