Compile Data Set for Download or QSAR
maximum 50k data
Found 126 of ic50 data for polymerid = 3035
TargetKiSS-1 receptor(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM26349((2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-3-(4-hydroxyp...)
Affinity DataIC50:  0.0820nMAssay Description:Binding affinity to human KISS1RMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKiSS-1 receptor(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50392401(CHEMBL2151642)
Affinity DataIC50:  0.110nMAssay Description:Binding affinity to human KISS1RMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKiSS-1 receptor(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM26349((2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-3-(4-hydroxyp...)
Affinity DataIC50:  0.120nMpH: 7.3 T: 2°CAssay Description:Membranes were incubated with [125I] kisspeptin-15 and increasing concentrations of test compound in binding buffer. The reaction mixtures were dilut...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKiSS-1 receptor(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM26349((2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-3-(4-hydroxyp...)
Affinity DataIC50:  0.120nMAssay Description:Displacement of [125I]kisspeptin-15 from GPR54More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKiSS-1 receptor(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM26339((2R,3E)-N-[(1S)-4-carbamimidamido-1-{[(1S)-1-carba...)
Affinity DataIC50:  0.120nMpH: 7.3 T: 2°CAssay Description:Membranes were incubated with [125I] kisspeptin-15 and increasing concentrations of test compound in binding buffer. The reaction mixtures were dilut...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKiSS-1 receptor(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM26339((2R,3E)-N-[(1S)-4-carbamimidamido-1-{[(1S)-1-carba...)
Affinity DataIC50:  0.120nMAssay Description:Displacement of [125I]kisspeptin-15 from GPR54More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKiSS-1 receptor(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM107307(US8592379, 19)
Affinity DataIC50:  0.120nMAssay Description:Binding inhibition assay using human GPR54.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKiSS-1 receptor(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50392412(CHEMBL2151653)
Affinity DataIC50:  0.130nMAssay Description:Binding affinity to human KISS1RMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKiSS-1 receptor(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50392405(CHEMBL2151646)
Affinity DataIC50:  0.160nMAssay Description:Binding affinity to human KISS1RMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKiSS-1 receptor(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50392413(CHEMBL2151654)
Affinity DataIC50:  0.190nMAssay Description:Binding affinity to human KISS1RMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKiSS-1 receptor(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50392409(CHEMBL2151650)
Affinity DataIC50:  0.190nMAssay Description:Binding affinity to human KISS1RMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKiSS-1 receptor(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM26347((2R,4S)-N-[(1S)-4-carbamimidamido-1-{[(1S)-1-carba...)
Affinity DataIC50:  0.240nMpH: 7.3 T: 2°CAssay Description:Membranes were incubated with [125I] kisspeptin-15 and increasing concentrations of test compound in binding buffer. The reaction mixtures were dilut...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKiSS-1 receptor(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM107314(US8592379, 36 | US8592379, 37)
Affinity DataIC50:  0.240nMAssay Description:Binding inhibition assay using human GPR54.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetKiSS-1 receptor(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50392414(CHEMBL2151655)
Affinity DataIC50:  0.280nMAssay Description:Binding affinity to human KISS1RMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKiSS-1 receptor(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50392411(CHEMBL2151652)
Affinity DataIC50:  0.300nMAssay Description:Binding affinity to human KISS1RMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKiSS-1 receptor(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50392408(CHEMBL2151649)
Affinity DataIC50:  0.430nMAssay Description:Binding affinity to human KISS1RMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKiSS-1 receptor(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50392406(CHEMBL2151647)
Affinity DataIC50:  0.490nMAssay Description:Binding affinity to human KISS1RMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKiSS-1 receptor(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50392404(CHEMBL2151645)
Affinity DataIC50:  0.510nMAssay Description:Binding affinity to human KISS1RMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKiSS-1 receptor(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50392403(CHEMBL2151644)
Affinity DataIC50:  0.610nMAssay Description:Binding affinity to human KISS1RMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKiSS-1 receptor(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50392410(CHEMBL2151651)
Affinity DataIC50:  0.700nMAssay Description:Binding affinity to human KISS1RMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKiSS-1 receptor(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM107306(US8592379, 1)
Affinity DataIC50:  0.710nMAssay Description:Binding inhibition assay using human GPR54.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetKiSS-1 receptor(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM26338((2S)-N-[(1S)-4-carbamimidamido-1-{[(1S)-1-carbamoy...)
Affinity DataIC50:  0.710nMpH: 7.3 T: 2°CAssay Description:Membranes were incubated with [125I] kisspeptin-15 and increasing concentrations of test compound in binding buffer. The reaction mixtures were dilut...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKiSS-1 receptor(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM26338((2S)-N-[(1S)-4-carbamimidamido-1-{[(1S)-1-carbamoy...)
Affinity DataIC50:  0.710nMAssay Description:Displacement of [125I]kisspeptin-15 from GPR54More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKiSS-1 receptor(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50392407(CHEMBL2151648)
Affinity DataIC50:  0.860nMAssay Description:Binding affinity to human KISS1RMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKiSS-1 receptor(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM107308(US8592379, 20)
Affinity DataIC50:  1.20nMAssay Description:Binding inhibition assay using human GPR54.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKiSS-1 receptor(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM26340((2S)-N-[(1S)-4-carbamimidamido-1-{[(1S)-1-carbamoy...)
Affinity DataIC50:  1.20nMpH: 7.3 T: 2°CAssay Description:Membranes were incubated with [125I] kisspeptin-15 and increasing concentrations of test compound in binding buffer. The reaction mixtures were dilut...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKiSS-1 receptor(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50392402(CHEMBL2151643)
Affinity DataIC50:  2.80nMAssay Description:Binding affinity to human KISS1RMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKiSS-1 receptor(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50322299(CHEMBL1173643 | N-[3-Cyano-6-(4-fluoro-2-hydroxyph...)
Affinity DataIC50:  3.60nMAssay Description:Displacement of [125I]metastin from human GPR54 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKiSS-1 receptor(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50320821(CHEMBL1163809 | N-(4-(3-(3-aminopropanamido)phenyl...)
Affinity DataIC50:  3.70nMAssay Description:Displacement of [125I]metastin(40-54) from human GPR54 receptor expressed in CHO cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKiSS-1 receptor(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50320821(CHEMBL1163809 | N-(4-(3-(3-aminopropanamido)phenyl...)
Affinity DataIC50:  3.70nMAssay Description:Displacement of [125I]metastin from human GPR54 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKiSS-1 receptor(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50322292(CHEMBL1171484 | N-{3-Cyano-6-(4-fluoro-2-hydroxyph...)
Affinity DataIC50:  4.10nMAssay Description:Displacement of [125I]metastin from human GPR54 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKiSS-1 receptor(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM107309(US8592379, 21)
Affinity DataIC50:  4.60nMAssay Description:Binding inhibition assay using human GPR54.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKiSS-1 receptor(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM26341((2E)-N-[(1S)-4-carbamimidamido-1-{[(1S)-1-carbamoy...)
Affinity DataIC50:  4.60nMpH: 7.3 T: 2°CAssay Description:Membranes were incubated with [125I] kisspeptin-15 and increasing concentrations of test compound in binding buffer. The reaction mixtures were dilut...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKiSS-1 receptor(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50322307(CHEMBL1169901 | N-[3-Cyano-6-(4-fluoro-2-hydroxyph...)
Affinity DataIC50:  4.60nMAssay Description:Displacement of [125I]metastin from human GPR54 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKiSS-1 receptor(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM107312(US8592379, 24a/24b | US8592379, 35)
Affinity DataIC50:  5.70nMAssay Description:Binding inhibition assay using human GPR54.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetKiSS-1 receptor(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM26345((2R,4R)-N-[(1S)-4-carbamimidamido-1-{[(1S)-1-carba...)
Affinity DataIC50:  5.70nMpH: 7.3 T: 2°CAssay Description:Membranes were incubated with [125I] kisspeptin-15 and increasing concentrations of test compound in binding buffer. The reaction mixtures were dilut...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKiSS-1 receptor(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50322300(CHEMBL1173644 | N-{3-Cyano-4-[3-(1,4-diazepan-1-yl...)
Affinity DataIC50:  7.30nMAssay Description:Displacement of [125I]metastin from human GPR54 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKiSS-1 receptor(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50320810(CHEMBL1165222 | N-(4-(3-(3-aminopropanamido)phenyl...)
Affinity DataIC50:  7.40nMAssay Description:Displacement of [125I]metastin(40-54) from human GPR54 receptor expressed in CHO cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKiSS-1 receptor(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50320810(CHEMBL1165222 | N-(4-(3-(3-aminopropanamido)phenyl...)
Affinity DataIC50:  7.40nMAssay Description:Displacement of [125I]metastin from human GPR54 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKiSS-1 receptor(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50322309(CHEMBL1170903 | N-[3-Cyano-6-(4-fluoro-2-hydroxyph...)
Affinity DataIC50:  7.90nMAssay Description:Displacement of [125I]metastin from human GPR54 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKiSS-1 receptor(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50320822(CHEMBL1163736 | N-[4-{3-[(2-Aminoethyl)carbamoyl]p...)
Affinity DataIC50:  8nMAssay Description:Displacement of [125I]metastin(40-54) from human GPR54 receptor expressed in CHO cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKiSS-1 receptor(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50322313(CHEMBL1170896 | rac-N-[3-Cyano-4-(3-{[3-(ethylamin...)
Affinity DataIC50:  8nMAssay Description:Displacement of [125I]metastin from human GPR54 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKiSS-1 receptor(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50322293(CHEMBL1170911 | N-[3-Cyano-6-(4-fluoro-2-hydroxyph...)
Affinity DataIC50:  8.40nMAssay Description:Displacement of [125I]metastin from human GPR54 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKiSS-1 receptor(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50442961(CHEMBL3086284)
Affinity DataIC50:  8.90nMAssay Description:Inhibition of human KISS1R expressed in CHO cells assessed as inhibition of KISS1R-mediated cell growth after 4 days by cell counting kit-8 assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKiSS-1 receptor(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50392405(CHEMBL2151646)
Affinity DataIC50:  9.70nMAssay Description:Inhibition of human KISS1R expressed in CHO cells assessed as inhibition of KISS1R-mediated cell growth after 4 days by cell counting kit-8 assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKiSS-1 receptor(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50322319(CHEMBL1170692 | rac-N-{3-Cyano-6-(4-fluoro-2-hydro...)
Affinity DataIC50:  9.70nMAssay Description:Displacement of [125I]metastin from human GPR54 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKiSS-1 receptor(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50322303(CHEMBL1170870 | N-{3-Cyano-6-(4-fluoro-2-hydroxyph...)
Affinity DataIC50:  9.70nMAssay Description:Displacement of [125I]metastin from human GPR54 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKiSS-1 receptor(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50320811(CHEMBL1163896 | N-{4-[3-(beta-Alanylamino)phenyl]-...)
Affinity DataIC50:  9.80nMAssay Description:Displacement of [125I]metastin(40-54) from human GPR54 receptor expressed in CHO cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKiSS-1 receptor(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50322310(CHEMBL1170904 | N-[3-Cyano-6-(4-fluoro-2-hydroxyph...)
Affinity DataIC50:  10nMAssay Description:Displacement of [125I]metastin from human GPR54 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKiSS-1 receptor(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50322318(CHEMBL1170685 | rac-N-[3-Cyano-4-(3-{[3-(ethylamin...)
Affinity DataIC50:  10nMAssay Description:Displacement of [125I]metastin from human GPR54 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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