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Compile Data Set for Download or QSAR

Found 529 hits of ic50 data for polymerid = 3431   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
5-hydroxytryptamine receptor 7


(Homo sapiens (Human))
BDBM392076
PNG
(US10301272, Example 7/9)
Show SMILES CC(C)(C)NS(=O)(=O)c1ccc(-c2sc(nc2CC2CCCCC2)C(=O)N[C@H]2C[C@@H](C2)C(O)=O)c2ccccc12
Show InChI InChI=1S/C30H37N3O5S2/c1-30(2,3)33-40(37,38)25-14-13-23(21-11-7-8-12-22(21)25)26-24(15-18-9-5-4-6-10-18)32-28(39-26)27(34)31-20-16-19(17-20)29(35)36/h7-8,11-14,18-20,33H,4-6,9-10,15-17H2,1-3H3,(H,31,34)(H,35,36)/t19-,20-
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n/an/a 0.390n/an/an/an/an/an/a



Phenex Pharmaceuticals AG

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human recombinant 5-HT7 receptor after 120 mins by scintillation counting analysis


Bioorg Med Chem Lett 28: 1446-1455 (2018)

More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Homo sapiens (Human))
BDBM10755
PNG
(14C-5-hydroxy tryptamine creatinine disulfate | 2-...)
Show SMILES NCCc1c[nH]c2ccc(O)cc12
Show InChI InChI=1S/C10H12N2O/c11-4-3-7-6-12-10-2-1-8(13)5-9(7)10/h1-2,5-6,12-13H,3-4,11H2
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n/an/a 0.470n/an/an/an/an/an/a



The University of Newcastle

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human recombinant 5-HT7 receptor expressed in CHO cells after 120 mins by scintillation counting


J Med Chem 60: 349-361 (2017)


Article DOI: 10.1021/acs.jmedchem.6b01422
BindingDB Entry DOI: 10.7270/Q27M0B6T
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Homo sapiens (Human))
BDBM50098551
PNG
((R)-3-(2-(2-(4-methylpiperidin-1-yl)ethyl)pyrrolid...)
Show SMILES CC1CCN(CC[C@H]2CCCN2S(=O)(=O)c2cccc(O)c2)CC1
Show InChI InChI=1/C18H28N2O3S/c1-15-7-11-19(12-8-15)13-9-16-4-3-10-20(16)24(22,23)18-6-2-5-17(21)14-18/h2,5-6,14-16,21H,3-4,7-13H2,1H3/t16-/s2
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n/an/a 0.900n/an/an/an/an/an/a



Korea Institute of Science and Technology

Curated by ChEMBL


Assay Description
Antagonist activity at human 5-HT7 receptor expressed in HEK293 cells assessed as inhibition of Gs protein-mediated cAMP accumulation by luminescence...


J Med Chem 61: 7218-7233 (2018)

More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Homo sapiens (Human))
BDBM50098551
PNG
((R)-3-(2-(2-(4-methylpiperidin-1-yl)ethyl)pyrrolid...)
Show SMILES CC1CCN(CC[C@H]2CCCN2S(=O)(=O)c2cccc(O)c2)CC1
Show InChI InChI=1/C18H28N2O3S/c1-15-7-11-19(12-8-15)13-9-16-4-3-10-20(16)24(22,23)18-6-2-5-17(21)14-18/h2,5-6,14-16,21H,3-4,7-13H2,1H3/t16-/s2
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n/an/a 0.930n/an/an/an/an/an/a



Jagiellonian University Medical College

Curated by ChEMBL


Assay Description
Antagonist activity at human 5-HT7 receptor expressed in CHO-K1 cells assessed as decrease in serotonin-induced cAMP level after 1 hr by TR-FRET assa...


Bioorg Med Chem Lett 28: 2039-2049 (2018)

More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Homo sapiens (Human))
BDBM50098551
PNG
((R)-3-(2-(2-(4-methylpiperidin-1-yl)ethyl)pyrrolid...)
Show SMILES CC1CCN(CC[C@H]2CCCN2S(=O)(=O)c2cccc(O)c2)CC1
Show InChI InChI=1/C18H28N2O3S/c1-15-7-11-19(12-8-15)13-9-16-4-3-10-20(16)24(22,23)18-6-2-5-17(21)14-18/h2,5-6,14-16,21H,3-4,7-13H2,1H3/t16-/s2
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n/an/a 0.933n/an/an/an/an/an/a



Korea Institute of Science and Technology

Curated by ChEMBL


Assay Description
Antagonist activity at human 5-HT7 receptor expressed in HEK293 cells assessed as inhibition of Gs protein-mediated cAMP accumulation by luminescence...


J Med Chem 61: 7218-7233 (2018)

More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Homo sapiens (Human))
BDBM78940
PNG
(METHIOTHEPIN | MLS000859918 | Methiothepin mesylat...)
Show SMILES CSc1ccc2Sc3ccccc3CC(N3CCN(C)CC3)c2c1
Show InChI InChI=1S/C20H24N2S2/c1-21-9-11-22(12-10-21)18-13-15-5-3-4-6-19(15)24-20-8-7-16(23-2)14-17(18)20/h3-8,14,18H,9-13H2,1-2H3
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n/an/a 1.5n/an/an/an/an/an/a



Adamed Ltd.

Curated by ChEMBL


Assay Description
Antagonist activity at human recombinant 5-HT7 receptor assessed as inhibition of serotonin-induced cAMP accumulation


J Med Chem 57: 4543-57 (2014)


Article DOI: 10.1021/jm401895u
BindingDB Entry DOI: 10.7270/Q2N29ZHX
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Homo sapiens (Human))
BDBM50425433
PNG
(METHIOTHEPINE)
Show SMILES CSc1ccc2CC=C(CCN)c2c1
Show InChI InChI=1S/C12H15NS/c1-14-11-5-4-9-2-3-10(6-7-13)12(9)8-11/h3-5,8H,2,6-7,13H2,1H3
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n/an/a 2.20n/an/an/an/an/an/a



Jagiellonian University Medical College

Curated by ChEMBL


Assay Description
Antagonist activity at human 5HT7 receptor expressed in HEK293 assessed as inhibition of 5HT-induced cAMP accumulation


Eur J Med Chem 60: 42-50 (2013)


Article DOI: 10.1016/j.ejmech.2012.11.042
BindingDB Entry DOI: 10.7270/Q21V5G98
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Homo sapiens (Human))
BDBM10755
PNG
(14C-5-hydroxy tryptamine creatinine disulfate | 2-...)
Show SMILES NCCc1c[nH]c2ccc(O)cc12
Show InChI InChI=1S/C10H12N2O/c11-4-3-7-6-12-10-2-1-8(13)5-9(7)10/h1-2,5-6,12-13H,3-4,11H2
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n/an/a 2.5n/an/an/an/an/an/a



Jagiellonian University Medical College

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human recombinant 5HT7 receptor expressed in CHO cells measured after 120 mins by scintillation counting method


Bioorg Med Chem 25: 471-482 (2017)


Article DOI: 10.1016/j.bmc.2016.11.014
BindingDB Entry DOI: 10.7270/Q2CF9S3S
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Homo sapiens (Human))
BDBM10755
PNG
(14C-5-hydroxy tryptamine creatinine disulfate | 2-...)
Show SMILES NCCc1c[nH]c2ccc(O)cc12
Show InChI InChI=1S/C10H12N2O/c11-4-3-7-6-12-10-2-1-8(13)5-9(7)10/h1-2,5-6,12-13H,3-4,11H2
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n/an/a 2.5n/an/an/an/an/an/a



Jagiellonian University Medical College

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human recombinant 5-HT7 receptor expressed in CHO cells


Bioorg Med Chem 24: 1793-810 (2016)


Article DOI: 10.1016/j.bmc.2016.03.006
BindingDB Entry DOI: 10.7270/Q2J67JS7
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Homo sapiens (Human))
BDBM10755
PNG
(14C-5-hydroxy tryptamine creatinine disulfate | 2-...)
Show SMILES NCCc1c[nH]c2ccc(O)cc12
Show InChI InChI=1S/C10H12N2O/c11-4-3-7-6-12-10-2-1-8(13)5-9(7)10/h1-2,5-6,12-13H,3-4,11H2
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n/an/a 2.55n/an/an/an/an/an/a



Tom's of Maine

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human 5HT7 receptor expressed in CHO cells


J Nat Prod 66: 535-7 (2003)


Article DOI: 10.1021/np0205102
BindingDB Entry DOI: 10.7270/Q2CZ36WZ
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Homo sapiens (Human))
BDBM78940
PNG
(METHIOTHEPIN | MLS000859918 | Methiothepin mesylat...)
Show SMILES CSc1ccc2Sc3ccccc3CC(N3CCN(C)CC3)c2c1
Show InChI InChI=1S/C20H24N2S2/c1-21-9-11-22(12-10-21)18-13-15-5-3-4-6-19(15)24-20-8-7-16(23-2)14-17(18)20/h3-8,14,18H,9-13H2,1-2H3
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n/an/a 3.10n/an/an/an/an/an/a



Institute of Science and Technology

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human recombinant 5HT7 receptor


Bioorg Med Chem 16: 2570-8 (2008)


Article DOI: 10.1016/j.bmc.2007.11.049
BindingDB Entry DOI: 10.7270/Q2JW8FRT
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Homo sapiens (Human))
BDBM50098551
PNG
((R)-3-(2-(2-(4-methylpiperidin-1-yl)ethyl)pyrrolid...)
Show SMILES CC1CCN(CC[C@H]2CCCN2S(=O)(=O)c2cccc(O)c2)CC1
Show InChI InChI=1/C18H28N2O3S/c1-15-7-11-19(12-8-15)13-9-16-4-3-10-20(16)24(22,23)18-6-2-5-17(21)14-18/h2,5-6,14-16,21H,3-4,7-13H2,1H3/t16-/s2
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n/an/a 3.70n/an/an/an/an/an/a



Yonsei University

Curated by ChEMBL


Assay Description
Antagonist activity at human 5-HT7R expressed in HEK293 cells assessed as inhibition of serotonin stimulated-cAMP levels preincubated for 10 mins fol...


Eur J Med Chem 123: 180-190 (2016)


Article DOI: 10.1016/j.ejmech.2016.07.029
BindingDB Entry DOI: 10.7270/Q27D2X36
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Homo sapiens (Human))
BDBM50098551
PNG
((R)-3-(2-(2-(4-methylpiperidin-1-yl)ethyl)pyrrolid...)
Show SMILES CC1CCN(CC[C@H]2CCCN2S(=O)(=O)c2cccc(O)c2)CC1
Show InChI InChI=1/C18H28N2O3S/c1-15-7-11-19(12-8-15)13-9-16-4-3-10-20(16)24(22,23)18-6-2-5-17(21)14-18/h2,5-6,14-16,21H,3-4,7-13H2,1H3/t16-/s2
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n/an/a 3.70n/an/an/an/an/an/a



Yonsei University

Curated by ChEMBL


Assay Description
Antagonist activity at human 5-HT7R expressed in HEK293 cells assessed as inhibition of serotonin stimulated-cAMP levels preincubated for 10 mins fol...


Eur J Med Chem 123: 180-190 (2016)


Article DOI: 10.1016/j.ejmech.2016.07.029
BindingDB Entry DOI: 10.7270/Q27D2X36
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Homo sapiens (Human))
BDBM352210
PNG
(US10239868, Entry 14 | US10287274, Entry 14 | US98...)
Show SMILES CCC1(CC)CC(CCN2CCN(CC2)c2ccccc2C(C)C)OC1=O
Show InChI InChI=1/C23H36N2O2/c1-5-23(6-2)17-19(27-22(23)26)11-12-24-13-15-25(16-14-24)21-10-8-7-9-20(21)18(3)4/h7-10,18-19H,5-6,11-17H2,1-4H3
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n/an/a 6n/an/an/an/an/an/a



TEMPLE UNIVERSITY OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION

US Patent


Assay Description
A solution of the compound of the disclosure to be tested is prepared as a 1-mg/ml stock in Assay Buffer or DMSO according to its solubility. A simil...


US Patent US10287274 (2019)

More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Homo sapiens (Human))
BDBM352210
PNG
(US10239868, Entry 14 | US10287274, Entry 14 | US98...)
Show SMILES CCC1(CC)CC(CCN2CCN(CC2)c2ccccc2C(C)C)OC1=O
Show InChI InChI=1/C23H36N2O2/c1-5-23(6-2)17-19(27-22(23)26)11-12-24-13-15-25(16-14-24)21-10-8-7-9-20(21)18(3)4/h7-10,18-19H,5-6,11-17H2,1-4H3
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n/an/a 6n/an/an/an/an/an/a



TEMPLE UNIVERSITY OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION

US Patent


Assay Description
A stock concentration of 5 nM [3H]LSD (lysergic acid diethyl amide) is prepared in 50 mM Tris-HCl, 10 mM MgCl2, 1 mM EDTA, pH 7.4 (Assay Buffer). Ali...


US Patent US9802924 (2017)


Article DOI: 10.1021/jm0602864
BindingDB Entry DOI: 10.7270/Q25Q4Z7N
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Homo sapiens (Human))
BDBM352210
PNG
(US10239868, Entry 14 | US10287274, Entry 14 | US98...)
Show SMILES CCC1(CC)CC(CCN2CCN(CC2)c2ccccc2C(C)C)OC1=O
Show InChI InChI=1/C23H36N2O2/c1-5-23(6-2)17-19(27-22(23)26)11-12-24-13-15-25(16-14-24)21-10-8-7-9-20(21)18(3)4/h7-10,18-19H,5-6,11-17H2,1-4H3
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n/an/a 6n/an/an/an/an/an/a



TEMPLE UNIVERSITY OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION

US Patent


Assay Description
A solution of the compound of the disclosure to be tested is prepared as a 1-mg/ml stock in Assay Buffer or DMSO according to its solubility. A simil...


US Patent US10239868 (2019)

More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Homo sapiens (Human))
BDBM50306820
PNG
(CHEMBL602878 | N-(Cyclopropylmethyl)-N-(3-(4-(3-(t...)
Show SMILES FC(F)(F)c1cccc(c1)N1CCN(CCCN(CC2CC2)S(=O)(=O)c2cccc3cccnc23)CC1
Show InChI InChI=1S/C27H31F3N4O2S/c28-27(29,30)23-7-2-8-24(19-23)33-17-15-32(16-18-33)13-4-14-34(20-21-10-11-21)37(35,36)25-9-1-5-22-6-3-12-31-26(22)25/h1-3,5-9,12,19,21H,4,10-11,13-18,20H2
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n/an/a 6.30n/an/an/an/an/an/a



Ewha Womans University

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human recombinant 5HT7 receptor expressed in CHO cells


Bioorg Med Chem 18: 1665-75 (2010)


Article DOI: 10.1016/j.bmc.2009.12.067
BindingDB Entry DOI: 10.7270/Q2R78F99
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Homo sapiens (Human))
BDBM9274
PNG
(CHEMBL1822893 | US8835436, Example 8)
Show SMILES Cc1nc(C(=O)NCCN2CCN(CC2)c2cccc(Cl)c2Cl)c(C)n1-c1ccccc1
Show InChI InChI=1S/C24H27Cl2N5O/c1-17-23(28-18(2)31(17)19-7-4-3-5-8-19)24(32)27-11-12-29-13-15-30(16-14-29)21-10-6-9-20(25)22(21)26/h3-10H,11-16H2,1-2H3,(H,27,32)
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n/an/a 6.80n/an/an/an/an/an/a



Green Cross Corporation

Curated by ChEMBL


Assay Description
Inhibition of 5HT7 receptor by competition binding assay


J Med Chem 54: 6305-18 (2011)


Article DOI: 10.1021/jm200682b
BindingDB Entry DOI: 10.7270/Q2SX6DMC
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Homo sapiens (Human))
BDBM352200
PNG
(US10239868, Entry 4 | US10287274, Entry 4 | US9802...)
Show SMILES CCC1(CC)CC(CCN2CCN(CC2)c2ccc(C)cc2)OC1=O
Show InChI InChI=1/C21H32N2O2/c1-4-21(5-2)16-19(25-20(21)24)10-11-22-12-14-23(15-13-22)18-8-6-17(3)7-9-18/h6-9,19H,4-5,10-16H2,1-3H3
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n/an/a 10n/an/an/an/an/an/a



TEMPLE UNIVERSITY OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION

US Patent


Assay Description
A solution of the compound of the disclosure to be tested is prepared as a 1-mg/ml stock in Assay Buffer or DMSO according to its solubility. A simil...


US Patent US10287274 (2019)

More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Homo sapiens (Human))
BDBM352200
PNG
(US10239868, Entry 4 | US10287274, Entry 4 | US9802...)
Show SMILES CCC1(CC)CC(CCN2CCN(CC2)c2ccc(C)cc2)OC1=O
Show InChI InChI=1/C21H32N2O2/c1-4-21(5-2)16-19(25-20(21)24)10-11-22-12-14-23(15-13-22)18-8-6-17(3)7-9-18/h6-9,19H,4-5,10-16H2,1-3H3
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n/an/a 10n/an/an/an/an/an/a



TEMPLE UNIVERSITY OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION

US Patent


Assay Description
A solution of the compound of the disclosure to be tested is prepared as a 1-mg/ml stock in Assay Buffer or DMSO according to its solubility. A simil...


US Patent US10239868 (2019)

More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Homo sapiens (Human))
BDBM352200
PNG
(US10239868, Entry 4 | US10287274, Entry 4 | US9802...)
Show SMILES CCC1(CC)CC(CCN2CCN(CC2)c2ccc(C)cc2)OC1=O
Show InChI InChI=1/C21H32N2O2/c1-4-21(5-2)16-19(25-20(21)24)10-11-22-12-14-23(15-13-22)18-8-6-17(3)7-9-18/h6-9,19H,4-5,10-16H2,1-3H3
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n/an/a 10n/an/an/an/an/an/a



TEMPLE UNIVERSITY OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION

US Patent


Assay Description
A stock concentration of 5 nM [3H]LSD (lysergic acid diethyl amide) is prepared in 50 mM Tris-HCl, 10 mM MgCl2, 1 mM EDTA, pH 7.4 (Assay Buffer). Ali...


US Patent US9802924 (2017)


Article DOI: 10.1021/jm0602864
BindingDB Entry DOI: 10.7270/Q25Q4Z7N
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Homo sapiens (Human))
BDBM50352724
PNG
(CHEMBL1822896 | US8835436, Example 6)
Show SMILES Cc1nc(C(=O)NCCCN2CCN(CC2)c2cccc(Cl)c2Cl)c(C)n1-c1ccccc1
Show InChI InChI=1S/C25H29Cl2N5O/c1-18-24(29-19(2)32(18)20-8-4-3-5-9-20)25(33)28-12-7-13-30-14-16-31(17-15-30)22-11-6-10-21(26)23(22)27/h3-6,8-11H,7,12-17H2,1-2H3,(H,28,33)
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n/an/a 11n/an/an/an/an/an/a



Green Cross Corporation

Curated by ChEMBL


Assay Description
Inhibition of 5HT7 receptor by competition binding assay


J Med Chem 54: 6305-18 (2011)


Article DOI: 10.1021/jm200682b
BindingDB Entry DOI: 10.7270/Q2SX6DMC
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Homo sapiens (Human))
BDBM50375936
PNG
(CHEMBL260907)
Show SMILES CCOc1ccccc1N1CCN(CCCC(=O)NCc2nc3ccc(F)cc3c(=O)n2-c2ccccc2)CC1
Show InChI InChI=1S/C31H34FN5O3/c1-2-40-28-12-7-6-11-27(28)36-19-17-35(18-20-36)16-8-13-30(38)33-22-29-34-26-15-14-23(32)21-25(26)31(39)37(29)24-9-4-3-5-10-24/h3-7,9-12,14-15,21H,2,8,13,16-20,22H2,1H3,(H,33,38)
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n/an/a 12.0n/an/an/an/an/an/a



Sharif University of Technology

Curated by ChEMBL


Assay Description
Inhibition of 5HT7 receptor by radioligand binding assay


Eur J Med Chem 44: 1463-70 (2009)


Article DOI: 10.1016/j.ejmech.2008.09.050
BindingDB Entry DOI: 10.7270/Q2QV3NRM
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Homo sapiens (Human))
BDBM50261124
PNG
(CHEMBL495678 | Naphthalene-2-sulfonic acid {3-[4-(...)
Show SMILES FC(F)(F)c1cccc(c1)N1CCN(CCCNS(=O)(=O)c2ccc3ccccc3c2)CC1
Show InChI InChI=1S/C24H26F3N3O2S/c25-24(26,27)21-7-3-8-22(18-21)30-15-13-29(14-16-30)12-4-11-28-33(31,32)23-10-9-19-5-1-2-6-20(19)17-23/h1-3,5-10,17-18,28H,4,11-16H2
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n/an/a 12n/an/an/an/an/an/a



Ewha Womans University

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human recombinant 5HT7 receptor expressed in CHO cell membrane


Bioorg Med Chem 16: 5405-12 (2008)


Article DOI: 10.1016/j.bmc.2008.04.023
BindingDB Entry DOI: 10.7270/Q2RX9BVH
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Homo sapiens (Human))
BDBM50375936
PNG
(CHEMBL260907)
Show SMILES CCOc1ccccc1N1CCN(CCCC(=O)NCc2nc3ccc(F)cc3c(=O)n2-c2ccccc2)CC1
Show InChI InChI=1S/C31H34FN5O3/c1-2-40-28-12-7-6-11-27(28)36-19-17-35(18-20-36)16-8-13-30(38)33-22-29-34-26-15-14-23(32)21-25(26)31(39)37(29)24-9-4-3-5-10-24/h3-7,9-12,14-15,21H,2,8,13,16-20,22H2,1H3,(H,33,38)
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n/an/a 12n/an/an/an/an/an/a



Institute of Science and Technology

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human recombinant 5HT7 receptor


Bioorg Med Chem 16: 2570-8 (2008)


Article DOI: 10.1016/j.bmc.2007.11.049
BindingDB Entry DOI: 10.7270/Q2JW8FRT
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Homo sapiens (Human))
BDBM50306819
PNG
(CHEMBL602677 | N-(Cyclopropylmethyl)-N-(3-(4-(2-me...)
Show SMILES COc1ccccc1N1CCN(CCCN(CC2CC2)S(=O)(=O)c2cccc3cccnc23)CC1
Show InChI InChI=1S/C27H34N4O3S/c1-34-25-10-3-2-9-24(25)30-19-17-29(18-20-30)15-6-16-31(21-22-12-13-22)35(32,33)26-11-4-7-23-8-5-14-28-27(23)26/h2-5,7-11,14,22H,6,12-13,15-21H2,1H3
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n/an/a 12.3n/an/an/an/an/an/a



Ewha Womans University

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human recombinant 5HT7 receptor expressed in CHO cells


Bioorg Med Chem 18: 1665-75 (2010)


Article DOI: 10.1016/j.bmc.2009.12.067
BindingDB Entry DOI: 10.7270/Q2R78F99
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Homo sapiens (Human))
BDBM352214
PNG
(US10239868, Entry 18 | US10287274, Entry 18 | US98...)
Show SMILES CCC1(CC)CC(CCN2CCc3ccccc3C2)OC1=O
Show InChI InChI=1/C19H27NO2/c1-3-19(4-2)13-17(22-18(19)21)10-12-20-11-9-15-7-5-6-8-16(15)14-20/h5-8,17H,3-4,9-14H2,1-2H3
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n/an/a 13n/an/an/an/an/an/a



TEMPLE UNIVERSITY OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION

US Patent


Assay Description
A solution of the compound of the disclosure to be tested is prepared as a 1-mg/ml stock in Assay Buffer or DMSO according to its solubility. A simil...


US Patent US10287274 (2019)

More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Homo sapiens (Human))
BDBM352214
PNG
(US10239868, Entry 18 | US10287274, Entry 18 | US98...)
Show SMILES CCC1(CC)CC(CCN2CCc3ccccc3C2)OC1=O
Show InChI InChI=1/C19H27NO2/c1-3-19(4-2)13-17(22-18(19)21)10-12-20-11-9-15-7-5-6-8-16(15)14-20/h5-8,17H,3-4,9-14H2,1-2H3
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n/an/a 13n/an/an/an/an/an/a



TEMPLE UNIVERSITY OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION

US Patent


Assay Description
A solution of the compound of the disclosure to be tested is prepared as a 1-mg/ml stock in Assay Buffer or DMSO according to its solubility. A simil...


US Patent US10239868 (2019)

More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Homo sapiens (Human))
BDBM352214
PNG
(US10239868, Entry 18 | US10287274, Entry 18 | US98...)
Show SMILES CCC1(CC)CC(CCN2CCc3ccccc3C2)OC1=O
Show InChI InChI=1/C19H27NO2/c1-3-19(4-2)13-17(22-18(19)21)10-12-20-11-9-15-7-5-6-8-16(15)14-20/h5-8,17H,3-4,9-14H2,1-2H3
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n/an/a 13n/an/an/an/an/an/a



TEMPLE UNIVERSITY OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION

US Patent


Assay Description
A stock concentration of 5 nM [3H]LSD (lysergic acid diethyl amide) is prepared in 50 mM Tris-HCl, 10 mM MgCl2, 1 mM EDTA, pH 7.4 (Assay Buffer). Ali...


US Patent US9802924 (2017)


Article DOI: 10.1021/jm0602864
BindingDB Entry DOI: 10.7270/Q25Q4Z7N
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Homo sapiens (Human))
BDBM50497431
PNG
(CHEMBL3343672)
Show SMILES NC(N)=NC(=O)c1ccc2-c3ccccc3[C@@]3(CCCO3)c2c1
Show InChI InChI=1S/C18H17N3O2/c19-17(20)21-16(22)11-6-7-13-12-4-1-2-5-14(12)18(15(13)10-11)8-3-9-23-18/h1-2,4-7,10H,3,8-9H2,(H4,19,20,21,22)/t18-/m0/s1
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n/an/a 15n/an/an/an/an/an/a



Astellas Pharma Inc

Curated by ChEMBL


Assay Description
Antagonist activity at human 5-HT7 receptor expressed in CHO cells assessed as cAMP production by EIA system


Bioorg Med Chem 22: 6026-38 (2014)

More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Homo sapiens (Human))
BDBM50497423
PNG
(CHEMBL3343670)
Show SMILES Cl.NC(N)=NC(=O)c1ccc2-c3ccccc3C3(CCCO3)c2c1
Show InChI InChI=1S/C18H17N3O2.ClH/c19-17(20)21-16(22)11-6-7-13-12-4-1-2-5-14(12)18(15(13)10-11)8-3-9-23-18;/h1-2,4-7,10H,3,8-9H2,(H4,19,20,21,22);1H
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n/an/a 16n/an/an/an/an/an/a



Astellas Pharma Inc

Curated by ChEMBL


Assay Description
Antagonist activity at human 5-HT7 receptor expressed in CHO cells assessed as cAMP production by EIA system


Bioorg Med Chem 22: 6026-38 (2014)

More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Homo sapiens (Human))
BDBM50375919
PNG
(CHEMBL406221)
Show SMILES CCOc1ccccc1N1CCN(CCCC(=O)NCc2nc3ccc(F)cc3c(=O)n2-c2ccc(OC)cc2)CC1
Show InChI InChI=1S/C32H36FN5O4/c1-3-42-29-8-5-4-7-28(29)37-19-17-36(18-20-37)16-6-9-31(39)34-22-30-35-27-15-10-23(33)21-26(27)32(40)38(30)24-11-13-25(41-2)14-12-24/h4-5,7-8,10-15,21H,3,6,9,16-20,22H2,1-2H3,(H,34,39)
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n/an/a 16n/an/an/an/an/an/a



Institute of Science and Technology

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human recombinant 5HT7 receptor


Bioorg Med Chem 16: 2570-8 (2008)


Article DOI: 10.1016/j.bmc.2007.11.049
BindingDB Entry DOI: 10.7270/Q2JW8FRT
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Homo sapiens (Human))
BDBM50375919
PNG
(CHEMBL406221)
Show SMILES CCOc1ccccc1N1CCN(CCCC(=O)NCc2nc3ccc(F)cc3c(=O)n2-c2ccc(OC)cc2)CC1
Show InChI InChI=1S/C32H36FN5O4/c1-3-42-29-8-5-4-7-28(29)37-19-17-36(18-20-37)16-6-9-31(39)34-22-30-35-27-15-10-23(33)21-26(27)32(40)38(30)24-11-13-25(41-2)14-12-24/h4-5,7-8,10-15,21H,3,6,9,16-20,22H2,1-2H3,(H,34,39)
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n/an/a 16n/an/an/an/an/an/a



Sharif University of Technology

Curated by ChEMBL


Assay Description
Inhibition of 5HT7 receptor by radioligand binding assay


Eur J Med Chem 44: 1463-70 (2009)


Article DOI: 10.1016/j.ejmech.2008.09.050
BindingDB Entry DOI: 10.7270/Q2QV3NRM
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Homo sapiens (Human))
BDBM50375924
PNG
(CHEMBL261742)
Show SMILES CCOc1ccccc1N1CCN(CCCC(=O)NCc2nc3ccc(F)cc3c(=O)n2-c2cccc(OC)c2)CC1
Show InChI InChI=1S/C32H36FN5O4/c1-3-42-29-11-5-4-10-28(29)37-18-16-36(17-19-37)15-7-12-31(39)34-22-30-35-27-14-13-23(33)20-26(27)32(40)38(30)24-8-6-9-25(21-24)41-2/h4-6,8-11,13-14,20-21H,3,7,12,15-19,22H2,1-2H3,(H,34,39)
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n/an/a 16n/an/an/an/an/an/a



Sharif University of Technology

Curated by ChEMBL


Assay Description
Inhibition of 5HT7 receptor by radioligand binding assay


Eur J Med Chem 44: 1463-70 (2009)


Article DOI: 10.1016/j.ejmech.2008.09.050
BindingDB Entry DOI: 10.7270/Q2QV3NRM
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Homo sapiens (Human))
BDBM50375924
PNG
(CHEMBL261742)
Show SMILES CCOc1ccccc1N1CCN(CCCC(=O)NCc2nc3ccc(F)cc3c(=O)n2-c2cccc(OC)c2)CC1
Show InChI InChI=1S/C32H36FN5O4/c1-3-42-29-11-5-4-10-28(29)37-18-16-36(17-19-37)15-7-12-31(39)34-22-30-35-27-14-13-23(33)20-26(27)32(40)38(30)24-8-6-9-25(21-24)41-2/h4-6,8-11,13-14,20-21H,3,7,12,15-19,22H2,1-2H3,(H,34,39)
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n/an/a 16n/an/an/an/an/an/a



Institute of Science and Technology

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human recombinant 5HT7 receptor


Bioorg Med Chem 16: 2570-8 (2008)


Article DOI: 10.1016/j.bmc.2007.11.049
BindingDB Entry DOI: 10.7270/Q2JW8FRT
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Homo sapiens (Human))
BDBM352240
PNG
(US10239868, Entry 42 | US10287274, Entry 42 | US98...)
Show SMILES O=C1OC(CCN2CCN(CC2)c2ccccc2N2CCOCC2)CC11CCCC1
Show InChI InChI=1/C24H35N3O3/c28-23-24(8-3-4-9-24)19-20(30-23)7-10-25-11-13-26(14-12-25)21-5-1-2-6-22(21)27-15-17-29-18-16-27/h1-2,5-6,20H,3-4,7-19H2
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n/an/a 17n/an/an/an/an/an/a



TEMPLE UNIVERSITY OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION

US Patent


Assay Description
A solution of the compound of the disclosure to be tested is prepared as a 1-mg/ml stock in Assay Buffer or DMSO according to its solubility. A simil...


US Patent US10239868 (2019)

More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Homo sapiens (Human))
BDBM352240
PNG
(US10239868, Entry 42 | US10287274, Entry 42 | US98...)
Show SMILES O=C1OC(CCN2CCN(CC2)c2ccccc2N2CCOCC2)CC11CCCC1
Show InChI InChI=1/C24H35N3O3/c28-23-24(8-3-4-9-24)19-20(30-23)7-10-25-11-13-26(14-12-25)21-5-1-2-6-22(21)27-15-17-29-18-16-27/h1-2,5-6,20H,3-4,7-19H2
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n/an/a 17n/an/an/an/an/an/a



TEMPLE UNIVERSITY OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION

US Patent


Assay Description
A stock concentration of 5 nM [3H]LSD (lysergic acid diethyl amide) is prepared in 50 mM Tris-HCl, 10 mM MgCl2, 1 mM EDTA, pH 7.4 (Assay Buffer). Ali...


US Patent US9802924 (2017)


Article DOI: 10.1021/jm0602864
BindingDB Entry DOI: 10.7270/Q25Q4Z7N
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Homo sapiens (Human))
BDBM352240
PNG
(US10239868, Entry 42 | US10287274, Entry 42 | US98...)
Show SMILES O=C1OC(CCN2CCN(CC2)c2ccccc2N2CCOCC2)CC11CCCC1
Show InChI InChI=1/C24H35N3O3/c28-23-24(8-3-4-9-24)19-20(30-23)7-10-25-11-13-26(14-12-25)21-5-1-2-6-22(21)27-15-17-29-18-16-27/h1-2,5-6,20H,3-4,7-19H2
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n/an/a 17n/an/an/an/an/an/a



TEMPLE UNIVERSITY OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION

US Patent


Assay Description
A solution of the compound of the disclosure to be tested is prepared as a 1-mg/ml stock in Assay Buffer or DMSO according to its solubility. A simil...


US Patent US10287274 (2019)

More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Homo sapiens (Human))
BDBM50403962
PNG
(CHEMBL81485)
Show SMILES CNCC1CC2N(O1)c1ccccc1Cc1ccccc21
Show InChI InChI=1/C18H20N2O/c1-19-12-15-11-18-16-8-4-2-6-13(16)10-14-7-3-5-9-17(14)20(18)21-15/h2-9,15,18-19H,10-12H2,1H3
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n/an/a 19n/an/an/an/an/an/a



Janssen-Cilag S.A.

Curated by ChEMBL


Assay Description
Binding affinity for human cloned 5-hydroxytryptamine 7 receptor


Bioorg Med Chem Lett 12: 243-8 (2001)


Article DOI: 10.1016/s0960-894x(01)00721-1
BindingDB Entry DOI: 10.7270/Q23J3F4C
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Homo sapiens (Human))
BDBM50375953
PNG
(CHEMBL258785)
Show SMILES CCOc1ccccc1N1CCN(CCCC(=O)NCc2nc3cc(F)ccc3c(=O)n2-c2ccccc2)CC1
Show InChI InChI=1S/C31H34FN5O3/c1-2-40-28-12-7-6-11-27(28)36-19-17-35(18-20-36)16-8-13-30(38)33-22-29-34-26-21-23(32)14-15-25(26)31(39)37(29)24-9-4-3-5-10-24/h3-7,9-12,14-15,21H,2,8,13,16-20,22H2,1H3,(H,33,38)
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n/an/a 19n/an/an/an/an/an/a



Institute of Science and Technology

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human recombinant 5HT7 receptor


Bioorg Med Chem 16: 2570-8 (2008)


Article DOI: 10.1016/j.bmc.2007.11.049
BindingDB Entry DOI: 10.7270/Q2JW8FRT
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Homo sapiens (Human))
BDBM50375953
PNG
(CHEMBL258785)
Show SMILES CCOc1ccccc1N1CCN(CCCC(=O)NCc2nc3cc(F)ccc3c(=O)n2-c2ccccc2)CC1
Show InChI InChI=1S/C31H34FN5O3/c1-2-40-28-12-7-6-11-27(28)36-19-17-35(18-20-36)16-8-13-30(38)33-22-29-34-26-21-23(32)14-15-25(26)31(39)37(29)24-9-4-3-5-10-24/h3-7,9-12,14-15,21H,2,8,13,16-20,22H2,1H3,(H,33,38)
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n/an/a 19.0n/an/an/an/an/an/a



Sharif University of Technology

Curated by ChEMBL


Assay Description
Inhibition of 5HT7 receptor by radioligand binding assay


Eur J Med Chem 44: 1463-70 (2009)


Article DOI: 10.1016/j.ejmech.2008.09.050
BindingDB Entry DOI: 10.7270/Q2QV3NRM
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Homo sapiens (Human))
BDBM50261126
PNG
(CHEMBL497749 | N-(3-(4-(2-methoxyphenyl)piperazin-...)
Show SMILES COc1ccccc1N1CCN(CCCNS(=O)(=O)c2ccc3ccccc3c2)CC1
Show InChI InChI=1S/C24H29N3O3S/c1-30-24-10-5-4-9-23(24)27-17-15-26(16-18-27)14-6-13-25-31(28,29)22-12-11-20-7-2-3-8-21(20)19-22/h2-5,7-12,19,25H,6,13-18H2,1H3
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n/an/a 20n/an/an/an/an/an/a



Ewha Womans University

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human recombinant 5HT7 receptor expressed in CHO cell membrane


Bioorg Med Chem 16: 5405-12 (2008)


Article DOI: 10.1016/j.bmc.2008.04.023
BindingDB Entry DOI: 10.7270/Q2RX9BVH
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Homo sapiens (Human))
BDBM50375970
PNG
(CHEMBL428781)
Show SMILES COc1ccccc1N1CCN(CCCC(=O)NCc2nc3ccccc3c(=O)n2-c2ccccc2)CC1
Show InChI InChI=1S/C30H33N5O3/c1-38-27-15-8-7-14-26(27)34-20-18-33(19-21-34)17-9-16-29(36)31-22-28-32-25-13-6-5-12-24(25)30(37)35(28)23-10-3-2-4-11-23/h2-8,10-15H,9,16-22H2,1H3,(H,31,36)
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n/an/a 21.0n/an/an/an/an/an/a



Sharif University of Technology

Curated by ChEMBL


Assay Description
Inhibition of 5HT7 receptor by radioligand binding assay


Eur J Med Chem 44: 1463-70 (2009)


Article DOI: 10.1016/j.ejmech.2008.09.050
BindingDB Entry DOI: 10.7270/Q2QV3NRM
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Homo sapiens (Human))
BDBM352207
PNG
(US10239868, Entry 11 | US10287274, Entry 11 | US98...)
Show SMILES CCC1(CC)CC(CCN2CCN(CC2)c2ccccc2)OC1=O
Show InChI InChI=1/C20H30N2O2/c1-3-20(4-2)16-18(24-19(20)23)10-11-21-12-14-22(15-13-21)17-8-6-5-7-9-17/h5-9,18H,3-4,10-16H2,1-2H3
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n/an/a 21n/an/an/an/an/an/a



TEMPLE UNIVERSITY OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION

US Patent


Assay Description
A solution of the compound of the disclosure to be tested is prepared as a 1-mg/ml stock in Assay Buffer or DMSO according to its solubility. A simil...


US Patent US10287274 (2019)

More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Homo sapiens (Human))
BDBM352207
PNG
(US10239868, Entry 11 | US10287274, Entry 11 | US98...)
Show SMILES CCC1(CC)CC(CCN2CCN(CC2)c2ccccc2)OC1=O
Show InChI InChI=1/C20H30N2O2/c1-3-20(4-2)16-18(24-19(20)23)10-11-21-12-14-22(15-13-21)17-8-6-5-7-9-17/h5-9,18H,3-4,10-16H2,1-2H3
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n/an/a 21n/an/an/an/an/an/a



TEMPLE UNIVERSITY OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION

US Patent


Assay Description
A stock concentration of 5 nM [3H]LSD (lysergic acid diethyl amide) is prepared in 50 mM Tris-HCl, 10 mM MgCl2, 1 mM EDTA, pH 7.4 (Assay Buffer). Ali...


US Patent US9802924 (2017)


Article DOI: 10.1021/jm0602864
BindingDB Entry DOI: 10.7270/Q25Q4Z7N
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Homo sapiens (Human))
BDBM50375970
PNG
(CHEMBL428781)
Show SMILES COc1ccccc1N1CCN(CCCC(=O)NCc2nc3ccccc3c(=O)n2-c2ccccc2)CC1
Show InChI InChI=1S/C30H33N5O3/c1-38-27-15-8-7-14-26(27)34-20-18-33(19-21-34)17-9-16-29(36)31-22-28-32-25-13-6-5-12-24(25)30(37)35(28)23-10-3-2-4-11-23/h2-8,10-15H,9,16-22H2,1H3,(H,31,36)
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n/an/a 21n/an/an/an/an/an/a



Institute of Science and Technology

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human recombinant 5HT7 receptor


Bioorg Med Chem 16: 2570-8 (2008)


Article DOI: 10.1016/j.bmc.2007.11.049
BindingDB Entry DOI: 10.7270/Q2JW8FRT
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Homo sapiens (Human))
BDBM78940
PNG
(METHIOTHEPIN | MLS000859918 | Methiothepin mesylat...)
Show SMILES CSc1ccc2Sc3ccccc3CC(N3CCN(C)CC3)c2c1
Show InChI InChI=1S/C20H24N2S2/c1-21-9-11-22(12-10-21)18-13-15-5-3-4-6-19(15)24-20-8-7-16(23-2)14-17(18)20/h3-8,14,18H,9-13H2,1-2H3
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n/an/a 21n/an/an/an/an/an/a



Jagiellonian University Medical College

Curated by ChEMBL


Assay Description
Antagonist activity at human 5-HT7 receptor expressed in HEK293 cells assessed as inhibition of 5-CT-induced cAMP production preincubated for 15 mins...


Eur J Med Chem 112: 258-69 (2016)


Article DOI: 10.1016/j.ejmech.2016.02.024
BindingDB Entry DOI: 10.7270/Q2KH0Q50
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Homo sapiens (Human))
BDBM352207
PNG
(US10239868, Entry 11 | US10287274, Entry 11 | US98...)
Show SMILES CCC1(CC)CC(CCN2CCN(CC2)c2ccccc2)OC1=O
Show InChI InChI=1/C20H30N2O2/c1-3-20(4-2)16-18(24-19(20)23)10-11-21-12-14-22(15-13-21)17-8-6-5-7-9-17/h5-9,18H,3-4,10-16H2,1-2H3
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n/an/a 21n/an/an/an/an/an/a



TEMPLE UNIVERSITY OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION

US Patent


Assay Description
A solution of the compound of the disclosure to be tested is prepared as a 1-mg/ml stock in Assay Buffer or DMSO according to its solubility. A simil...


US Patent US10239868 (2019)

More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Homo sapiens (Human))
BDBM352238
PNG
(US10239868, Entry 39 | US10287274, Entry 39 | US98...)
Show SMILES CC(C)c1ccccc1N1CCN(CCC2CC3(CCCC3)C(=O)O2)CC1
Show InChI InChI=1/C23H34N2O2/c1-18(2)20-7-3-4-8-21(20)25-15-13-24(14-16-25)12-9-19-17-23(22(26)27-19)10-5-6-11-23/h3-4,7-8,18-19H,5-6,9-17H2,1-2H3
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n/an/a 24n/an/an/an/an/an/a



TEMPLE UNIVERSITY OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION

US Patent


Assay Description
A solution of the compound of the disclosure to be tested is prepared as a 1-mg/ml stock in Assay Buffer or DMSO according to its solubility. A simil...


US Patent US10239868 (2019)

More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 7


(Homo sapiens (Human))
BDBM50306839
PNG
(CHEMBL601885 | N-(Cyclohexylmethyl)-N-[3-(4-(2-met...)
Show SMILES COc1ccccc1N1CCN(CCCN(CC2CCCCC2)S(=O)(=O)c2cccc3cccnc23)CC1
Show InChI InChI=1S/C30H40N4O3S/c1-37-28-15-6-5-14-27(28)33-22-20-32(21-23-33)18-9-19-34(24-25-10-3-2-4-11-25)38(35,36)29-16-7-12-26-13-8-17-31-30(26)29/h5-8,12-17,25H,2-4,9-11,18-24H2,1H3
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n/an/a 24n/an/an/an/an/an/a



Ewha Womans University

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human recombinant 5HT7 receptor expressed in CHO cells


Bioorg Med Chem 18: 1665-75 (2010)


Article DOI: 10.1016/j.bmc.2009.12.067
BindingDB Entry DOI: 10.7270/Q2R78F99
More data for this
Ligand-Target Pair
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