Compile Data Set for Download or QSAR
maximum 50k data
Found 239 of ic50 data for polymerid = 49000724,49000727,49000728,5661
TargetMelatonin receptor type 1A(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50408628(CHEMBL139855)
Affinity DataIC50:  0.0126nMAssay Description:Melatonin receptor type 1A binding affinity measured using 2-[125I]iodomelatonin on ovine pars tuberalis membrane homogenates.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1A(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50114716(CHEMBL329263 | N-[2-(2-Benzyl-5-methoxy-benzofuran...)
Affinity DataIC50:  0.0158nMAssay Description:Melatonin receptor type 1A binding affinity measured using 2-[125I]iodomelatonin on ovine pars tuberalis membrane homogenates.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1A(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM103448(US8552037, 95)
Affinity DataIC50:  0.0220nMAssay Description:Binding assay using melatonin receptors 1 or 2.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMelatonin receptor type 1A(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM103446(US8552037, 93)
Affinity DataIC50:  0.0300nMAssay Description:Binding assay using melatonin receptors 1 or 2.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMelatonin receptor type 1A(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM103450(US8552037, 98)
Affinity DataIC50:  0.0380nMAssay Description:Binding assay using melatonin receptors 1 or 2.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMelatonin receptor type 1A(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM103443(US8552037, 90)
Affinity DataIC50:  0.0570nMAssay Description:Binding assay using melatonin receptors 1 or 2.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMelatonin receptor type 1A(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM103437(US8552037, 82)
Affinity DataIC50:  0.0680nMAssay Description:Binding assay using melatonin receptors 1 or 2.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMelatonin receptor type 1A(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM103439(US8552037, 84)
Affinity DataIC50:  0.0790nMAssay Description:Binding assay using melatonin receptors 1 or 2.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMelatonin receptor type 1A(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM103456(US8552037, 123)
Affinity DataIC50:  0.0950nMAssay Description:Binding assay using melatonin receptors 1 or 2.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMelatonin receptor type 1A(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM9019(CHEMBL45 | Melatonin | N-[2-(5-methoxy-1H-indol-3-...)
Affinity DataIC50:  0.110nMAssay Description:Displacement of [125I]2-iodomelatonin from human recombinant MT1 receptor expressed in CHO cells measured after 60 mins by scintillation counting met...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetMelatonin receptor type 1A(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM9019(CHEMBL45 | Melatonin | N-[2-(5-methoxy-1H-indol-3-...)
Affinity DataIC50:  0.110nMAssay Description:Displacement of [125I]2-iodomelatonin from human recombinant ML1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetMelatonin receptor type 1A(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM103445(US8552037, 92)
Affinity DataIC50:  0.130nMAssay Description:Binding assay using melatonin receptors 1 or 2.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMelatonin receptor type 1A(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM103442(US8552037, 89)
Affinity DataIC50:  0.150nMAssay Description:Binding assay using melatonin receptors 1 or 2.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMelatonin receptor type 1A(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM103449(US8552037, 97)
Affinity DataIC50:  0.150nMAssay Description:Binding assay using melatonin receptors 1 or 2.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMelatonin receptor type 1A(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50286970(CHEMBL11356 | N-[2-(3H-Benzo[f]chromen-10-yl)-ethy...)
Affinity DataIC50:  0.158nMAssay Description:Melatonin receptor type 1A binding affinity measured using 2-[125I]iodomelatonin on ovine pars tuberalis membrane homogenates.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1A(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM392076(US10301272, Example 7/9)
Affinity DataIC50:  0.170nMAssay Description:Displacement of [125I]NDP-alpha -MSH from human recombinant MT1 receptor after 240 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1A(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM103440(US8552037, 86)
Affinity DataIC50:  0.190nMAssay Description:Binding assay using melatonin receptors 1 or 2.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMelatonin receptor type 1A(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM9019(CHEMBL45 | Melatonin | N-[2-(5-methoxy-1H-indol-3-...)
Affinity DataIC50:  0.200nMAssay Description:Binding affinity to human MT1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetMelatonin receptor type 1A(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM9019(CHEMBL45 | Melatonin | N-[2-(5-methoxy-1H-indol-3-...)
Affinity DataIC50:  0.200nMAssay Description:Displacement of 2-[125I]iodomelatonin from human MT1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetMelatonin receptor type 1A(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM103438(US8552037, 83)
Affinity DataIC50:  0.25nMAssay Description:Binding assay using melatonin receptors 1 or 2.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMelatonin receptor type 1A(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM103455(US8552037, 121)
Affinity DataIC50:  0.25nMAssay Description:Binding assay using melatonin receptors 1 or 2.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMelatonin receptor type 1A(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50286973(CHEMBL274358 | N-[2-(2,3-Dihydro-1H-benzo[f]chrome...)
Affinity DataIC50:  0.251nMAssay Description:Melatonin receptor type 1A binding affinity measured using 2-[125I]iodomelatonin on ovine pars tuberalis membrane homogenates.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1A(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50408640(CHEMBL337764)
Affinity DataIC50:  0.316nMAssay Description:Melatonin receptor type 1A binding affinity measured using 2-[125I]iodomelatonin on ovine pars tuberalis membrane homogenates.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1A(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM103436(US8552037, 81)
Affinity DataIC50:  0.330nMAssay Description:Binding assay using melatonin receptors 1 or 2.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMelatonin receptor type 1A(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM103452(US8552037, 100)
Affinity DataIC50:  0.360nMAssay Description:Binding assay using melatonin receptors 1 or 2.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMelatonin receptor type 1A(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM103454(US8552037, 116)
Affinity DataIC50:  0.540nMAssay Description:Binding assay using melatonin receptors 1 or 2.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMelatonin receptor type 1A(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50037242(CHEMBL323332 | N-(2-(5-methoxybenzofuran-3-yl)ethy...)
Affinity DataIC50:  0.600nMAssay Description:Displacement of 2-[125I]iodomelatonin from human MT1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1A(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM9019(CHEMBL45 | Melatonin | N-[2-(5-methoxy-1H-indol-3-...)
Affinity DataIC50:  0.600nMAssay Description:In vitro receptor binding at MT1 (Melatonin) receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetMelatonin receptor type 1A(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM103453(US8552037, 107)
Affinity DataIC50:  0.660nMAssay Description:Binding assay using melatonin receptors 1 or 2.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMelatonin receptor type 1A(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50408584(CHEMBL137998)
Affinity DataIC50:  0.794nMAssay Description:Melatonin receptor type 1A binding affinity measured using 2-[125I]iodomelatonin on ovine pars tuberalis membrane homogenates.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1A(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50408555(CHEMBL322762)
Affinity DataIC50:  0.794nMAssay Description:Melatonin receptor type 1A binding affinity measured using 2-[125I]iodomelatonin on ovine pars tuberalis membrane homogenates.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1A(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50408657(CHEMBL137878)
Affinity DataIC50:  0.794nMAssay Description:Melatonin receptor type 1A binding affinity measured using 2-[125I]iodomelatonin on ovine pars tuberalis membrane homogenates.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1A(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50342770(CHEMBL456727 | N-(2-(7-(methylthio)naphthalen-1-yl...)
Affinity DataIC50:  0.875nMAssay Description:Binding affinity to human MT1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1A(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM103441(US8552037, 87)
Affinity DataIC50:  0.880nMAssay Description:Binding assay using melatonin receptors 1 or 2.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMelatonin receptor type 1A(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM9019(CHEMBL45 | Melatonin | N-[2-(5-methoxy-1H-indol-3-...)
Affinity DataIC50:  1nMAssay Description:Binding affinity for melatonin 1A receptor was measured using 2-[125I]iodomelatonin on ovine pars tuberalis membrane homogenates.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetMelatonin receptor type 1A(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50408618(CHEMBL138321)
Affinity DataIC50:  1nMAssay Description:Melatonin receptor type 1A binding affinity measured using 2-[125I]iodomelatonin on ovine pars tuberalis membrane homogenates.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1A(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM29611(2-Iodomelatonin | CHEMBL289233 | Melatonin,2-Iodo)
Affinity DataIC50:  1nMAssay Description:Melatonin receptor type 1A binding affinity measured using 2-[125I]iodomelatonin on ovine pars tuberalis membrane homogenates.More data for this Ligand-Target Pair
TargetMelatonin receptor type 1A(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50282765(CHEMBL38728 | N-(6-Methoxy-9-methyl-2,3,4,9-tetrah...)
Affinity DataIC50:  1nMAssay Description:Melatonin receptor type 1A binding affinity measured using 2-[125I]iodomelatonin on ovine pars tuberalis membrane homogenates.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1A(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50408578(CHEMBL417151)
Affinity DataIC50:  1.26nMAssay Description:Melatonin receptor type 1A binding affinity measured using 2-[125I]iodomelatonin on ovine pars tuberalis membrane homogenates.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1A(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50286972(CHEMBL11404 | N-(2-Naphtho[2,1-b]furan-9-yl-ethyl)...)
Affinity DataIC50:  1.26nMAssay Description:Melatonin receptor type 1A binding affinity measured using 2-[125I]iodomelatonin on ovine pars tuberalis membrane homogenates.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1A(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50037219(CHEMBL109235 | N-[2-(5-Methoxy-benzo[b]thiophen-3-...)
Affinity DataIC50:  1.26nMAssay Description:Melatonin receptor type 1A binding affinity measured using 2-[125I]iodomelatonin on ovine pars tuberalis membrane homogenates.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1A(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50037253(2-Iodo-N-[2-(5-methoxy-1H-indol-3-yl)-ethyl]-aceta...)
Affinity DataIC50:  1.26nMAssay Description:Melatonin receptor type 1A binding affinity measured using 2-[125I]iodomelatonin on ovine pars tuberalis membrane homogenates.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1A(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50037242(CHEMBL323332 | N-(2-(5-methoxybenzofuran-3-yl)ethy...)
Affinity DataIC50:  1.58nMAssay Description:Melatonin receptor type 1A binding affinity measured using 2-[125I]iodomelatonin on ovine pars tuberalis membrane homogenates.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1A(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50037249(CHEMBL109086 | Cyclopropanecarboxylic acid [2-(6-f...)
Affinity DataIC50:  2nMAssay Description:Melatonin receptor type 1A binding affinity measured using 2-[125I]iodomelatonin on ovine pars tuberalis membrane homogenates.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1A(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50408556(CHEMBL37771)
Affinity DataIC50:  2nMAssay Description:Melatonin receptor type 1A binding affinity measured using 2-[125I]iodomelatonin on ovine pars tuberalis membrane homogenates.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1A(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50408591(CHEMBL138766)
Affinity DataIC50:  2nMAssay Description:Melatonin receptor type 1A binding affinity measured using 2-[125I]iodomelatonin on ovine pars tuberalis membrane homogenates.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1A(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50011340(CHEMBL3260981)
Affinity DataIC50:  2.30nMAssay Description:Binding affinity to MT1 receptor (unknown origin) expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1A(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50408649(CHEMBL37703)
Affinity DataIC50:  2.51nMAssay Description:Melatonin receptor type 1A binding affinity measured using 2-[125I]iodomelatonin on ovine pars tuberalis membrane homogenates.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1A(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50408631(CHEMBL138817)
Affinity DataIC50:  2.51nMAssay Description:Melatonin receptor type 1A binding affinity measured using 2-[125I]iodomelatonin on ovine pars tuberalis membrane homogenates.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1A(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50295869(CHEMBL556908 | N-[2-(8-Methoxy-2-methyl-1,2,3,4-te...)
Affinity DataIC50:  3.14nMAssay Description:Agonist activity at human MT1 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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