Compile Data Set for Download or QSAR
maximum 50k data
Found 21 of ic50 data for polymerid = 50000316
Target5'-nucleotidase(Mus musculus)
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM50546288(CHEMBL4743437)
Affinity DataIC50:  0.160nMAssay Description:Inhibition of CD73 in mouse CD8-positive T cells using AMP as substrate preincubated for 60 mins followed by substrate addition and measured after 2....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5'-nucleotidase(Mus musculus)
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM50527134(CHEMBL4471306 | US20230295213, Compound a)
Affinity DataIC50:  0.660nMAssay Description:Inhibition of CD73 in mouse CD8-positive T cells using AMP as substrate preincubated for 60 mins followed by substrate addition and measured after 2....More data for this Ligand-Target Pair
Target5'-nucleotidase(Mus musculus)
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM50546280(CHEMBL4761506)
Affinity DataIC50:  0.830nMAssay Description:Inhibition of CD73 in mouse CD8-positive T cells using AMP as substrate preincubated for 60 mins followed by substrate addition and measured after 2....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
Target5'-nucleotidase(Mus musculus)
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM50561221(CHEMBL4745473 | US11377469, Example 95)
Affinity DataIC50:  3nMAssay Description:Inhibition of soluble mouse CD73 incubated for 60 mins before addition of AMP and further incubated for 60 mins by colorimetric assayMore data for this Ligand-Target Pair
Target5'-nucleotidase(Mus musculus)
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM50561221(CHEMBL4745473 | US11377469, Example 95)
Affinity DataIC50:  13nMAssay Description:Inhibition of mouse CD73 expressed in CHO cells incubated for 60 mins before addition of AMP and further incubated for 60 mins by colorimetric assayMore data for this Ligand-Target Pair
Target5'-nucleotidase(Mus musculus)
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM4078(6,7,13,14-tetrahydroxy-2,9-dioxatetracyclo[6.6.2.0...)
Affinity DataIC50:  40nMAssay Description:Inhibition of mouse CD73More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5'-nucleotidase(Mus musculus)
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM18136(ADP, alpha beta-me | AMPCPP | [({[(2R,3S,4R,5R)-5-...)
Affinity DataIC50:  4.63E+3nMAssay Description:Inhibition of mouse CD73More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5'-nucleotidase(Mus musculus)
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM18136(ADP, alpha beta-me | AMPCPP | [({[(2R,3S,4R,5R)-5-...)
Affinity DataIC50:  4.63E+3nMAssay Description:Inhibition of mouse CD73 assessed as reduction in inorganic phosphate release upon substrate hydrolysis using AMP/ATP as substrate incubated for 1 hr...More data for this Ligand-Target Pair
In DepthDetails PubMed
Target5'-nucleotidase(Mus musculus)
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM50599943(CHEMBL5177276)
Affinity DataIC50:  1.47E+4nMAssay Description:Inhibition of mouse CD73 assessed as reduction in inorganic phosphate release upon substrate hydrolysis using AMP/ATP as substrate incubated for 1 hr...More data for this Ligand-Target Pair
In DepthDetails PubMed
Target5'-nucleotidase(Mus musculus)
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM50599939(CHEMBL5185215)
Affinity DataIC50:  3.36E+4nMAssay Description:Inhibition of mouse CD73 assessed as reduction in inorganic phosphate release upon substrate hydrolysis using AMP/ATP as substrate incubated for 1 hr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
Target5'-nucleotidase(Mus musculus)
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM23207((1R,2R,5S,8R,9R,10R,13R,14R,17S,19R)-5-(hydroxymet...)
Affinity DataIC50:  5.03E+4nMAssay Description:Inhibition of mouse CD73More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5'-nucleotidase(Mus musculus)
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM50599941(CHEMBL5190085)
Affinity DataIC50:  5.90E+4nMAssay Description:Inhibition of mouse CD73 assessed as reduction in inorganic phosphate release upon substrate hydrolysis using AMP/ATP as substrate incubated for 1 hr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
Target5'-nucleotidase(Mus musculus)
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM23208((1R,2R,5S,8R,9R,10R,13R,14R,17S,19R)-17-hydroxy-1,...)
Affinity DataIC50:  6.88E+4nMAssay Description:Inhibition of mouse CD73 assessed as reduction in inorganic phosphate release upon substrate hydrolysis using AMP/ATP as substrate incubated for 1 hr...More data for this Ligand-Target Pair
In DepthDetails PubMed
Target5'-nucleotidase(Mus musculus)
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM50599944(CHEMBL5187845)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of mouse CD73 assessed as reduction in inorganic phosphate release upon substrate hydrolysis using AMP/ATP as substrate incubated for 1 hr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
Target5'-nucleotidase(Mus musculus)
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM50599942(CHEMBL5207600)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of mouse CD73 assessed as reduction in inorganic phosphate release upon substrate hydrolysis using AMP/ATP as substrate incubated for 1 hr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
Target5'-nucleotidase(Mus musculus)
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM50599940(CHEMBL5207447)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of mouse CD73 assessed as reduction in inorganic phosphate release upon substrate hydrolysis using AMP/ATP as substrate incubated for 1 hr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
Target5'-nucleotidase(Mus musculus)
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM50599938(CHEMBL5170776)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of mouse CD73 assessed as reduction in inorganic phosphate release upon substrate hydrolysis using AMP/ATP as substrate incubated for 1 hr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
Target5'-nucleotidase(Mus musculus)
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM50599937(CHEMBL5177221)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of mouse CD73 assessed as reduction in inorganic phosphate release upon substrate hydrolysis using AMP/ATP as substrate incubated for 1 hr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
Target5'-nucleotidase(Mus musculus)
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM50599936(CHEMBL5191234)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of mouse CD73 assessed as reduction in inorganic phosphate release upon substrate hydrolysis using AMP/ATP as substrate incubated for 1 hr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
Target5'-nucleotidase(Mus musculus)
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM50599945(CHEMBL5170520)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of mouse CD73 assessed as reduction in inorganic phosphate release upon substrate hydrolysis using AMP/ATP as substrate incubated for 1 hr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
Target5'-nucleotidase(Mus musculus)
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM50241052(1,2,3,4,6-Pgg | 1,2,3,4,6-pentakis-O-(3,4,5-trihyd...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of mouse CD73More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed