Compile Data Set for Download or QSAR
maximum 50k data
Found 25 of ic50 data for polymerid = 50001807,50006184
Target7-dehydrocholesterol reductase(Homo sapiens (Human))
Martin-Luther-Universit£T Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50396754(CHEMBL2172347)
Affinity DataIC50:  2.30nMAssay Description:Inhibition of 7-dehydroxycholesterol reductase-mediated cholesterol biosynthesis in human HL60 cells assessed as inhibition of 2-[13C]acetate after 2...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target7-dehydrocholesterol reductase(Homo sapiens (Human))
Martin-Luther-Universit£T Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50411320(CHEMBL222694)
Affinity DataIC50:  30nMAssay Description:Growth inhibition of MDA-MB-231 cells containing antiestrogen binding sitesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target7-dehydrocholesterol reductase(Homo sapiens (Human))
Martin-Luther-Universit£T Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50411320(CHEMBL222694)
Affinity DataIC50:  30nMAssay Description:Growth inhibition of MCF7 cells expressing ER and antiestrogen binding sitesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target7-dehydrocholesterol reductase(Homo sapiens (Human))
Martin-Luther-Universit£T Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50411320(CHEMBL222694)
Affinity DataIC50:  40nMAssay Description:Growth inhibition of MDA-MB-435 cells containing antiestrogen binding sitesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target7-dehydrocholesterol reductase(Homo sapiens (Human))
Martin-Luther-Universit£T Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50411319(CHEMBL266892)
Affinity DataIC50:  50nMAssay Description:Growth inhibition of MDA-MB-435 cells containing antiestrogen binding sitesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target7-dehydrocholesterol reductase(Homo sapiens (Human))
Martin-Luther-Universit£T Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50411320(CHEMBL222694)
Affinity DataIC50:  60nMAssay Description:Growth inhibition of multidrug resistant MCF7/Adr cells containing antiestrogen binding sitesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target7-dehydrocholesterol reductase(Homo sapiens (Human))
Martin-Luther-Universit£T Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50411319(CHEMBL266892)
Affinity DataIC50:  70nMAssay Description:Growth inhibition of MCF7 cells expressing ER and antiestrogen binding sitesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target7-dehydrocholesterol reductase(Homo sapiens (Human))
Martin-Luther-Universit£T Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50411319(CHEMBL266892)
Affinity DataIC50:  80nMAssay Description:Growth inhibition of MDA-MB-231 cells containing antiestrogen binding sitesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target7-dehydrocholesterol reductase(Homo sapiens (Human))
Martin-Luther-Universit£T Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50396753(CHEMBL2172349)
Affinity DataIC50:  120nMAssay Description:Inhibition of 7-dehydroxycholesterol reductase-mediated cholesterol biosynthesis in human HL60 cells assessed as inhibition of 2-[13C]acetate after 2...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target7-dehydrocholesterol reductase(Homo sapiens (Human))
Martin-Luther-Universit£T Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM22984((8S,10S)-10-{[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-me...)
Affinity DataIC50:  150nMAssay Description:Growth inhibition of MDA-MB-435 cells containing antiestrogen binding sitesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target7-dehydrocholesterol reductase(Homo sapiens (Human))
Martin-Luther-Universit£T Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM22984((8S,10S)-10-{[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-me...)
Affinity DataIC50:  200nMAssay Description:Growth inhibition of MCF7 cells expressing ER and antiestrogen binding sitesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target7-dehydrocholesterol reductase(Homo sapiens (Human))
Martin-Luther-Universit£T Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM22984((8S,10S)-10-{[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-me...)
Affinity DataIC50:  300nMAssay Description:Growth inhibition of MDA-MB-231 cells containing antiestrogen binding sitesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target7-dehydrocholesterol reductase(Homo sapiens (Human))
Martin-Luther-Universit£T Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50412080(CHEMBL342394)
Affinity DataIC50:  400nMAssay Description:Displacement of [3H]tamoxifen from antiestrogen binding site in Sprague-Dawley rat liver by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target7-dehydrocholesterol reductase(Homo sapiens (Human))
Martin-Luther-Universit£T Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50170646(4-(2-{4-[(E)-3-(4-Chloro-phenyl)-allyl]-piperazin-...)
Affinity DataIC50:  500nMAssay Description:Inhibition of 7-dehydroxycholesterol reductase-mediated cholesterol biosynthesis in human HL60 cells assessed as inhibition of 2-[13C]acetate after 2...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target7-dehydrocholesterol reductase(Homo sapiens (Human))
Martin-Luther-Universit£T Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50412077((+)-PACHYSAMINE B)
Affinity DataIC50:  600nMAssay Description:Displacement of [3H]tamoxifen from antiestrogen binding site in Sprague-Dawley rat liver by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target7-dehydrocholesterol reductase(Homo sapiens (Human))
Martin-Luther-Universit£T Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50412082(CHEMBL455316)
Affinity DataIC50:  600nMAssay Description:Displacement of [3H]tamoxifen from antiestrogen binding site in Sprague-Dawley rat liver by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target7-dehydrocholesterol reductase(Homo sapiens (Human))
Martin-Luther-Universit£T Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50411319(CHEMBL266892)
Affinity DataIC50:  2.00E+3nMAssay Description:Growth inhibition of multidrug resistant MCF7/Adr cells containing antiestrogen binding sitesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target7-dehydrocholesterol reductase(Homo sapiens (Human))
Martin-Luther-Universit£T Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50412076(CHEMBL457817)
Affinity DataIC50:  2.80E+3nMAssay Description:Displacement of [3H]tamoxifen from antiestrogen binding site in Sprague-Dawley rat liver by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target7-dehydrocholesterol reductase(Homo sapiens (Human))
Martin-Luther-Universit£T Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50412083(CHEMBL458033)
Affinity DataIC50:  3.50E+3nMAssay Description:Displacement of [3H]tamoxifen from antiestrogen binding site in Sprague-Dawley rat liver by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target7-dehydrocholesterol reductase(Homo sapiens (Human))
Martin-Luther-Universit£T Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50412081(CHEMBL505436)
Affinity DataIC50:  6.80E+3nMAssay Description:Displacement of [3H]tamoxifen from antiestrogen binding site in Sprague-Dawley rat liver by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target7-dehydrocholesterol reductase(Homo sapiens (Human))
Martin-Luther-Universit£T Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50396752(CHEMBL2172350)
Affinity DataIC50:  7.30E+3nMAssay Description:Inhibition of 7-dehydroxycholesterol reductase-mediated cholesterol biosynthesis in human HL60 cells assessed as inhibition of 2-[13C]acetate after 2...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target7-dehydrocholesterol reductase(Homo sapiens (Human))
Martin-Luther-Universit£T Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50412079(CHEMBL456512)
Affinity DataIC50:  7.40E+3nMAssay Description:Displacement of [3H]tamoxifen from antiestrogen binding site in Sprague-Dawley rat liver by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target7-dehydrocholesterol reductase(Homo sapiens (Human))
Martin-Luther-Universit£T Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50135147((+)-axillaridine A | 14-(1-dimethylaminoethyl)-2,1...)
Affinity DataIC50:  8.00E+3nMAssay Description:Displacement of [3H]tamoxifen from antiestrogen binding site in Sprague-Dawley rat liver by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target7-dehydrocholesterol reductase(Homo sapiens (Human))
Martin-Luther-Universit£T Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM22984((8S,10S)-10-{[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-me...)
Affinity DataIC50:  1.00E+4nMAssay Description:Growth inhibition of multidrug resistant MCF7/Adr cells containing antiestrogen binding sitesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target7-dehydrocholesterol reductase(Homo sapiens (Human))
Martin-Luther-Universit£T Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50412078(EPIPACHYSAMINE D)
Affinity DataIC50: >2.00E+4nMAssay Description:Displacement of [3H]tamoxifen from antiestrogen binding site in Sprague-Dawley rat liver by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed