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Compile Data Set for Download or QSAR

Found 14 hits of ic50 data for polymerid = 50005949,50006462   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Serine racemase


(Mus musculus)
BDBM50038343
PNG
(CHEMBL3360546)
Show SMILES [Na+].[Na+].[O-]C(=O)C(Cl)(Cl)C([O-])=O
Show InChI InChI=1S/C3H2Cl2O4.2Na/c4-3(5,1(6)7)2(8)9;;/h(H,6,7)(H,8,9);;/q;2*+1/p-2
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n/an/a 5.70E+4n/an/an/an/an/an/a



Academy of Sciences of the Czech Republic

Curated by ChEMBL


Assay Description
Inhibition of mouse serine racemase using L-serine substrate by reversed-phase HPLC analysis


Eur J Med Chem 89: 189-97 (2014)


Article DOI: 10.1016/j.ejmech.2014.10.043
BindingDB Entry DOI: 10.7270/Q22N53WK
More data for this
Ligand-Target Pair
Serine racemase


(Mus musculus)
BDBM14673
PNG
(Fragment 3 | Malonic Acid | propanedioic acid)
Show SMILES OC(=O)CC(O)=O
Show InChI InChI=1S/C3H4O4/c4-2(5)1-3(6)7/h1H2,(H,4,5)(H,6,7)
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n/an/a 6.70E+4n/an/an/an/an/an/a



Academy of Sciences of the Czech Republic

Curated by ChEMBL


Assay Description
Inhibition of mouse serine racemase using L-serine substrate by reversed-phase HPLC analysis


Eur J Med Chem 89: 189-97 (2014)


Article DOI: 10.1016/j.ejmech.2014.10.043
BindingDB Entry DOI: 10.7270/Q22N53WK
More data for this
Ligand-Target Pair
Serine racemase


(Mus musculus)
BDBM50378531
PNG
(CHEMBL566071)
Show SMILES ONC(=O)CCC(=O)NO
Show InChI InChI=1S/C4H8N2O4/c7-3(5-9)1-2-4(8)6-10/h9-10H,1-2H2,(H,5,7)(H,6,8)
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n/an/a 9.00E+4n/an/an/an/an/an/a



Institute of Organic Chemistry and Biochemistry of the ASCR

Curated by ChEMBL


Assay Description
Inhibition of mouse recombinant serine racemase expressed in Escherichia coli MC1061 assessed as formation of D-serine after 30 mins by HPLC analysis


J Med Chem 52: 6032-41 (2009)


Article DOI: 10.1021/jm900775q
BindingDB Entry DOI: 10.7270/Q29G5NRV
More data for this
Ligand-Target Pair
Serine racemase


(Mus musculus)
BDBM50038354
PNG
(CHEBI:16513 | CHEMBL1794676)
Show SMILES OC(C(O)=O)C(O)=O
Show InChI InChI=1S/C3H4O5/c4-1(2(5)6)3(7)8/h1,4H,(H,5,6)(H,7,8)
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n/an/a 9.40E+4n/an/an/an/an/an/a



Academy of Sciences of the Czech Republic

Curated by ChEMBL


Assay Description
Inhibition of mouse serine racemase using L-serine substrate by reversed-phase HPLC analysis


Eur J Med Chem 89: 189-97 (2014)


Article DOI: 10.1016/j.ejmech.2014.10.043
BindingDB Entry DOI: 10.7270/Q22N53WK
More data for this
Ligand-Target Pair
Serine racemase


(Mus musculus)
BDBM50378530
PNG
(CHEMBL566494)
Show SMILES ONC(=O)CCCC(=O)NO
Show InChI InChI=1S/C5H10N2O4/c8-4(6-10)2-1-3-5(9)7-11/h10-11H,1-3H2,(H,6,8)(H,7,9)
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n/an/a 1.70E+5n/an/an/an/an/an/a



Institute of Organic Chemistry and Biochemistry of the ASCR

Curated by ChEMBL


Assay Description
Inhibition of mouse recombinant serine racemase expressed in Escherichia coli MC1061 assessed as formation of D-serine after 30 mins by HPLC analysis


J Med Chem 52: 6032-41 (2009)


Article DOI: 10.1021/jm900775q
BindingDB Entry DOI: 10.7270/Q29G5NRV
More data for this
Ligand-Target Pair
Serine racemase


(Mus musculus)
BDBM50378532
PNG
(CHEMBL569435)
Show SMILES ONC(=O)CC(=O)NO
Show InChI InChI=1S/C3H6N2O4/c6-2(4-8)1-3(7)5-9/h8-9H,1H2,(H,4,6)(H,5,7)
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n/an/a 3.70E+5n/an/an/an/an/an/a



Institute of Organic Chemistry and Biochemistry of the ASCR

Curated by ChEMBL


Assay Description
Inhibition of mouse recombinant serine racemase expressed in Escherichia coli MC1061 assessed as formation of D-serine after 30 mins by HPLC analysis


J Med Chem 52: 6032-41 (2009)


Article DOI: 10.1021/jm900775q
BindingDB Entry DOI: 10.7270/Q29G5NRV
More data for this
Ligand-Target Pair
Serine racemase


(Mus musculus)
BDBM92990
PNG
(Aminomalonate)
Show SMILES NC(C([O-])=O)C([O-])=O
Show InChI InChI=1S/C3H5NO4/c4-1(2(5)6)3(7)8/h1H,4H2,(H,5,6)(H,7,8)/p-2
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n/an/a 4.00E+5n/an/an/an/an/an/a



Academy of Sciences of the Czech Republic

Curated by ChEMBL


Assay Description
Inhibition of mouse serine racemase using L-serine substrate by reversed-phase HPLC analysis


Eur J Med Chem 89: 189-97 (2014)


Article DOI: 10.1016/j.ejmech.2014.10.043
BindingDB Entry DOI: 10.7270/Q22N53WK
More data for this
Ligand-Target Pair
Serine racemase


(Mus musculus)
BDBM50038342
PNG
(CHEMBL3360547)
Show SMILES [Na+].[Na+].[O-]C(=O)C(Cl)C([O-])=O
Show InChI InChI=1S/C3H3ClO4.2Na/c4-1(2(5)6)3(7)8;;/h1H,(H,5,6)(H,7,8);;/q;2*+1/p-2
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n/an/a 7.80E+5n/an/an/an/an/an/a



Academy of Sciences of the Czech Republic

Curated by ChEMBL


Assay Description
Inhibition of mouse serine racemase using L-serine substrate by reversed-phase HPLC analysis


Eur J Med Chem 89: 189-97 (2014)


Article DOI: 10.1016/j.ejmech.2014.10.043
BindingDB Entry DOI: 10.7270/Q22N53WK
More data for this
Ligand-Target Pair
Serine racemase


(Mus musculus)
BDBM50129194
PNG
((2S)-2-amino-4-(hydroxyamino)-4-oxobutanoic acidN(...)
Show SMILES N[C@@H](CC(=O)NO)C(O)=O
Show InChI InChI=1S/C4H8N2O4/c5-2(4(8)9)1-3(7)6-10/h2,10H,1,5H2,(H,6,7)(H,8,9)/t2-/m0/s1
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n/an/a 1.30E+6n/an/an/an/an/an/a



Institute of Organic Chemistry and Biochemistry of the ASCR

Curated by ChEMBL


Assay Description
Inhibition of mouse recombinant serine racemase expressed in Escherichia coli MC1061 assessed as formation of D-serine after 30 mins by HPLC analysis


J Med Chem 52: 6032-41 (2009)


Article DOI: 10.1021/jm900775q
BindingDB Entry DOI: 10.7270/Q29G5NRV
More data for this
Ligand-Target Pair
Serine racemase


(Mus musculus)
BDBM50038341
PNG
(CHEBI:30860 | METHYLMALONIC ACID)
Show SMILES CC(C(O)=O)C(O)=O
Show InChI InChI=1S/C4H6O4/c1-2(3(5)6)4(7)8/h2H,1H3,(H,5,6)(H,7,8)
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n/an/a 1.85E+6n/an/an/an/an/an/a



Academy of Sciences of the Czech Republic

Curated by ChEMBL


Assay Description
Inhibition of mouse serine racemase using L-serine substrate by reversed-phase HPLC analysis


Eur J Med Chem 89: 189-97 (2014)


Article DOI: 10.1016/j.ejmech.2014.10.043
BindingDB Entry DOI: 10.7270/Q22N53WK
More data for this
Ligand-Target Pair
Serine racemase


(Mus musculus)
BDBM50038340
PNG
(CHEMBL3360548)
Show SMILES [Na+].[Na+].[O-]C(=O)C(F)(F)C([O-])=O
Show InChI InChI=1S/C3H2F2O4.2Na/c4-3(5,1(6)7)2(8)9;;/h(H,6,7)(H,8,9);;/q;2*+1/p-2
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n/an/a 2.16E+6n/an/an/an/an/an/a



Academy of Sciences of the Czech Republic

Curated by ChEMBL


Assay Description
Inhibition of mouse serine racemase using L-serine substrate by reversed-phase HPLC analysis


Eur J Med Chem 89: 189-97 (2014)


Article DOI: 10.1016/j.ejmech.2014.10.043
BindingDB Entry DOI: 10.7270/Q22N53WK
More data for this
Ligand-Target Pair
Serine racemase


(Mus musculus)
BDBM50038339
PNG
(CHEMBL3360549)
Show SMILES CC(C)(C(O)=O)C(O)=O
Show InChI InChI=1S/C5H8O4/c1-5(2,3(6)7)4(8)9/h1-2H3,(H,6,7)(H,8,9)
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n/an/a 5.63E+6n/an/an/an/an/an/a



Academy of Sciences of the Czech Republic

Curated by ChEMBL


Assay Description
Inhibition of mouse serine racemase using L-serine substrate by reversed-phase HPLC analysis


Eur J Med Chem 89: 189-97 (2014)


Article DOI: 10.1016/j.ejmech.2014.10.043
BindingDB Entry DOI: 10.7270/Q22N53WK
More data for this
Ligand-Target Pair
Serine racemase


(Mus musculus)
BDBM50038338
PNG
(CHEMBL3360550)
Show SMILES OC(=O)C(C(O)=O)c1ccsc1
Show InChI InChI=1S/C7H6O4S/c8-6(9)5(7(10)11)4-1-2-12-3-4/h1-3,5H,(H,8,9)(H,10,11)
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n/an/a 7.03E+6n/an/an/an/an/an/a



Academy of Sciences of the Czech Republic

Curated by ChEMBL


Assay Description
Inhibition of mouse serine racemase using L-serine substrate by reversed-phase HPLC analysis


Eur J Med Chem 89: 189-97 (2014)


Article DOI: 10.1016/j.ejmech.2014.10.043
BindingDB Entry DOI: 10.7270/Q22N53WK
More data for this
Ligand-Target Pair
Serine racemase


(Mus musculus)
BDBM50038355
PNG
(CHEMBL3360551)
Show SMILES OCC(CO)(C([O-])=O)C([O-])=O
Show InChI InChI=1S/C5H8O6.2Na/c6-1-5(2-7,3(8)9)4(10)11;;/h6-7H,1-2H2,(H,8,9)(H,10,11);;/q;2*+1/p-2
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n/an/a 4.06E+7n/an/an/an/an/an/a



Academy of Sciences of the Czech Republic

Curated by ChEMBL


Assay Description
Inhibition of mouse serine racemase using L-serine substrate by reversed-phase HPLC analysis


Eur J Med Chem 89: 189-97 (2014)


Article DOI: 10.1016/j.ejmech.2014.10.043
BindingDB Entry DOI: 10.7270/Q22N53WK
More data for this
Ligand-Target Pair