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Compile Data Set for Download or QSAR

Found 445 hits of ic50 data for polymerid = 50006173,6542   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
UDP-3-O-acyl-GlcNAc deacetylase (LpxC)


(Pseudomonas aeruginosa)
BDBM264952
PNG
(US9718792, 95)
Show SMILES C[C@@](C[C@H]1CC(=NO1)c1ccc(cc1)-c1ccc(cc1)[C@@H](O)CO)(C(=O)NO)S(C)(=O)=O
Show InChI InChI=1S/C22H26N2O7S/c1-22(21(27)23-28,32(2,29)30)12-18-11-19(24-31-18)16-7-3-14(4-8-16)15-5-9-17(10-6-15)20(26)13-25/h3-10,18,20,25-26,28H,11-13H2,1-2H3,(H,23,27)/t18-,20+,22-/m1/s1
PDB

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B.MOAD
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PC sid
UniChem
US Patent
n/an/a<0.000100n/an/an/an/a7.525



Novartis AG

US Patent


Assay Description
The P. aeruginosa LpxC protein is produced according to the general method of Hyland et al (Journal of Bacteriology 1997 179, 2029-2037: Cloning, exp...


US Patent US9718792 (2017)

More data for this
Ligand-Target Pair
UDP-3-O-acyl-GlcNAc deacetylase (LpxC)


(Pseudomonas aeruginosa)
BDBM264925
PNG
(US9718792, 86)
Show SMILES COC(CO)Cc1ccc(cc1)-c1ccc(cc1)C1=NO[C@@H](C[C@](C)(C(=O)NO)S(C)(=O)=O)C1
Show InChI InChI=1S/C24H30N2O7S/c1-24(23(28)25-29,34(3,30)31)14-20-13-22(26-33-20)19-10-8-18(9-11-19)17-6-4-16(5-7-17)12-21(15-27)32-2/h4-11,20-21,27,29H,12-15H2,1-3H3,(H,25,28)/t20-,21?,24-/m1/s1
PDB

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PC sid
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US Patent
n/an/a<0.00100n/an/an/an/a7.525



Novartis AG

US Patent


Assay Description
The P. aeruginosa LpxC protein is produced according to the general method of Hyland et al (Journal of Bacteriology 1997 179, 2029-2037: Cloning, exp...


US Patent US9718792 (2017)

More data for this
Ligand-Target Pair
UDP-3-O-acyl-GlcNAc deacetylase (LpxC)


(Pseudomonas aeruginosa)
BDBM264928
PNG
(US9718792, 87)
Show SMILES Cc1cc(CO)ccc1-c1ccc(cc1)C1=NO[C@@H](C[C@](C)(C(=O)NO)S(C)(=O)=O)C1
Show InChI InChI=1S/C22H26N2O6S/c1-14-10-15(13-25)4-9-19(14)16-5-7-17(8-6-16)20-11-18(30-24-20)12-22(2,21(26)23-27)31(3,28)29/h4-10,18,25,27H,11-13H2,1-3H3,(H,23,26)/t18-,22-/m1/s1
PDB

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UniProtKB/SwissProt

B.MOAD
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PC sid
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US Patent
n/an/a<0.00100n/an/an/an/a7.525



Novartis AG

US Patent


Assay Description
The P. aeruginosa LpxC protein is produced according to the general method of Hyland et al (Journal of Bacteriology 1997 179, 2029-2037: Cloning, exp...


US Patent US9718792 (2017)

More data for this
Ligand-Target Pair
UDP-3-O-acyl-GlcNAc deacetylase (LpxC)


(Pseudomonas aeruginosa)
BDBM264931
PNG
(US9718792, 88)
Show SMILES C[C@@H](O)Cc1cc(F)c(c(F)c1)-c1ccc(cc1)C1=NO[C@@H](C[C@](C)(C(=O)NO)S(C)(=O)=O)C1
Show InChI InChI=1S/C23H26F2N2O6S/c1-13(28)8-14-9-18(24)21(19(25)10-14)16-6-4-15(5-7-16)20-11-17(33-27-20)12-23(2,22(29)26-30)34(3,31)32/h4-7,9-10,13,17,28,30H,8,11-12H2,1-3H3,(H,26,29)/t13-,17-,23-/m1/s1
PDB

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US Patent
n/an/a<0.00100n/an/an/an/a7.525



Novartis AG

US Patent


Assay Description
The P. aeruginosa LpxC protein is produced according to the general method of Hyland et al (Journal of Bacteriology 1997 179, 2029-2037: Cloning, exp...


US Patent US9718792 (2017)

More data for this
Ligand-Target Pair
UDP-3-O-acyl-GlcNAc deacetylase (LpxC)


(Pseudomonas aeruginosa)
BDBM264934
PNG
(US9718792, 89)
Show SMILES C[C@@H](O)Cc1ccc(c(F)c1)-c1ccc(cc1)C1=NO[C@@H](C[C@](C)(C(=O)NO)S(C)(=O)=O)C1
Show InChI InChI=1S/C23H27FN2O6S/c1-14(27)10-15-4-9-19(20(24)11-15)16-5-7-17(8-6-16)21-12-18(32-26-21)13-23(2,22(28)25-29)33(3,30)31/h4-9,11,14,18,27,29H,10,12-13H2,1-3H3,(H,25,28)/t14-,18-,23-/m1/s1
PDB

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US Patent
n/an/a<0.00100n/an/an/an/a7.525



Novartis AG

US Patent


Assay Description
The P. aeruginosa LpxC protein is produced according to the general method of Hyland et al (Journal of Bacteriology 1997 179, 2029-2037: Cloning, exp...


US Patent US9718792 (2017)

More data for this
Ligand-Target Pair
UDP-3-O-acyl-GlcNAc deacetylase (LpxC)


(Pseudomonas aeruginosa)
BDBM264937
PNG
(US9718792, 90)
Show SMILES C[C@@H](O)Cc1ccc(c(C)c1)-c1ccc(cc1)C1=NO[C@@H](C[C@](C)(C(=O)NO)S(C)(=O)=O)C1
Show InChI InChI=1S/C24H30N2O6S/c1-15-11-17(12-16(2)27)5-10-21(15)18-6-8-19(9-7-18)22-13-20(32-26-22)14-24(3,23(28)25-29)33(4,30)31/h5-11,16,20,27,29H,12-14H2,1-4H3,(H,25,28)/t16-,20-,24-/m1/s1
PDB

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UniProtKB/SwissProt

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GoogleScholar
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PC sid
UniChem
US Patent
n/an/a<0.00100n/an/an/an/a7.525



Novartis AG

US Patent


Assay Description
The P. aeruginosa LpxC protein is produced according to the general method of Hyland et al (Journal of Bacteriology 1997 179, 2029-2037: Cloning, exp...


US Patent US9718792 (2017)

More data for this
Ligand-Target Pair
UDP-3-O-acyl-GlcNAc deacetylase (LpxC)


(Pseudomonas aeruginosa)
BDBM264940
PNG
(US9718792, 91)
Show SMILES C[C@@](C[C@H]1CC(=NO1)c1ccc(cc1)-c1ccsc1)(C(=O)NO)S(C)(=O)=O
Show InChI InChI=1S/C18H20N2O5S2/c1-18(17(21)19-22,27(2,23)24)10-15-9-16(20-25-15)13-5-3-12(4-6-13)14-7-8-26-11-14/h3-8,11,15,22H,9-10H2,1-2H3,(H,19,21)/t15-,18-/m1/s1
PDB

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PC sid
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US Patent
n/an/a<0.00100n/an/an/an/a7.525



Novartis AG

US Patent


Assay Description
The P. aeruginosa LpxC protein is produced according to the general method of Hyland et al (Journal of Bacteriology 1997 179, 2029-2037: Cloning, exp...


US Patent US9718792 (2017)

More data for this
Ligand-Target Pair
UDP-3-O-acyl-GlcNAc deacetylase (LpxC)


(Pseudomonas aeruginosa)
BDBM264943
PNG
(US9718792, 92)
Show SMILES C[C@@](C[C@H]1CC(=NO1)c1ccc(cc1)-c1cnsc1)(C(=O)NO)S(C)(=O)=O
Show InChI InChI=1S/C17H19N3O5S2/c1-17(16(21)19-22,27(2,23)24)8-14-7-15(20-25-14)12-5-3-11(4-6-12)13-9-18-26-10-13/h3-6,9-10,14,22H,7-8H2,1-2H3,(H,19,21)/t14-,17-/m1/s1
PDB

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PC sid
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US Patent
n/an/a<0.00100n/an/an/an/a7.525



Novartis AG

US Patent


Assay Description
The P. aeruginosa LpxC protein is produced according to the general method of Hyland et al (Journal of Bacteriology 1997 179, 2029-2037: Cloning, exp...


US Patent US9718792 (2017)

More data for this
Ligand-Target Pair
UDP-3-O-acyl-GlcNAc deacetylase (LpxC)


(Pseudomonas aeruginosa)
BDBM264946
PNG
(US9718792, 93)
Show SMILES C[C@@H](O)[C@@H](O)Cc1ccc(cc1)-c1ccc(cc1)C1=NO[C@@H](C[C@](C)(C(=O)NO)S(C)(=O)=O)C1
Show InChI InChI=1S/C24H30N2O7S/c1-15(27)22(28)12-16-4-6-17(7-5-16)18-8-10-19(11-9-18)21-13-20(33-26-21)14-24(2,23(29)25-30)34(3,31)32/h4-11,15,20,22,27-28,30H,12-14H2,1-3H3,(H,25,29)/t15-,20-,22+,24-/m1/s1
PDB

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GoogleScholar
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PC sid
UniChem
US Patent
n/an/a<0.00100n/an/an/an/a7.525



Novartis AG

US Patent


Assay Description
The P. aeruginosa LpxC protein is produced according to the general method of Hyland et al (Journal of Bacteriology 1997 179, 2029-2037: Cloning, exp...


US Patent US9718792 (2017)

More data for this
Ligand-Target Pair
UDP-3-O-acyl-GlcNAc deacetylase (LpxC)


(Pseudomonas aeruginosa)
BDBM264949
PNG
(US9718792, 94)
Show SMILES C[C@@](C[C@H]1CC(=NO1)c1ccc(cc1)-c1ccc(cc1)[C@H](O)CO)(C(=O)NO)S(C)(=O)=O
Show InChI InChI=1S/C22H26N2O7S/c1-22(21(27)23-28,32(2,29)30)12-18-11-19(24-31-18)16-7-3-14(4-8-16)15-5-9-17(10-6-15)20(26)13-25/h3-10,18,20,25-26,28H,11-13H2,1-2H3,(H,23,27)/t18-,20-,22-/m1/s1
PDB

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UniProtKB/SwissProt

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GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a<0.00100n/an/an/an/a7.525



Novartis AG

US Patent


Assay Description
The P. aeruginosa LpxC protein is produced according to the general method of Hyland et al (Journal of Bacteriology 1997 179, 2029-2037: Cloning, exp...


US Patent US9718792 (2017)

More data for this
Ligand-Target Pair
UDP-3-O-acyl-GlcNAc deacetylase (LpxC)


(Pseudomonas aeruginosa)
BDBM264955
PNG
(US9718792, 96)
Show SMILES C[C@@](C[C@H]1CC(=NO1)c1ccc(cc1)-c1ccc(cc1)C(O)CCO)(C(=O)NO)S(C)(=O)=O
Show InChI InChI=1S/C23H28N2O7S/c1-23(22(28)24-29,33(2,30)31)14-19-13-20(25-32-19)17-7-3-15(4-8-17)16-5-9-18(10-6-16)21(27)11-12-26/h3-10,19,21,26-27,29H,11-14H2,1-2H3,(H,24,28)/t19-,21?,23-/m1/s1
PDB

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UniChem
US Patent
n/an/a<0.00100n/an/an/an/a7.525



Novartis AG

US Patent


Assay Description
The P. aeruginosa LpxC protein is produced according to the general method of Hyland et al (Journal of Bacteriology 1997 179, 2029-2037: Cloning, exp...


US Patent US9718792 (2017)

More data for this
Ligand-Target Pair
UDP-3-O-acyl-GlcNAc deacetylase (LpxC)


(Pseudomonas aeruginosa)
BDBM264958
PNG
(US9718792, 98)
Show SMILES C[C@@](C[C@H]1CC(=NO1)c1ccc(cc1)C#CC1CCOCC1)(C(=O)NO)S(C)(=O)=O
Show InChI InChI=1S/C21H26N2O6S/c1-21(20(24)22-25,30(2,26)27)14-18-13-19(23-29-18)17-7-5-15(6-8-17)3-4-16-9-11-28-12-10-16/h5-8,16,18,25H,9-14H2,1-2H3,(H,22,24)/t18-,21-/m1/s1
PDB

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US Patent
n/an/a 0.00100n/an/an/an/a7.525



Novartis AG

US Patent


Assay Description
The P. aeruginosa LpxC protein is produced according to the general method of Hyland et al (Journal of Bacteriology 1997 179, 2029-2037: Cloning, exp...


US Patent US9718792 (2017)

More data for this
Ligand-Target Pair
UDP-3-O-acyl-GlcNAc deacetylase (LpxC)


(Pseudomonas aeruginosa)
BDBM264961
PNG
(US9718792, 100)
Show SMILES C[C@@](C[C@H]1CC(=NO1)c1ccc(cc1)-c1c(F)cncc1F)(C(=O)NO)S(C)(=O)=O
Show InChI InChI=1S/C19H19F2N3O5S/c1-19(18(25)23-26,30(2,27)28)8-13-7-16(24-29-13)11-3-5-12(6-4-11)17-14(20)9-22-10-15(17)21/h3-6,9-10,13,26H,7-8H2,1-2H3,(H,23,25)/t13-,19-/m1/s1
PDB

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US Patent
n/an/a<0.00100n/an/an/an/a7.525



Novartis AG

US Patent


Assay Description
The P. aeruginosa LpxC protein is produced according to the general method of Hyland et al (Journal of Bacteriology 1997 179, 2029-2037: Cloning, exp...


US Patent US9718792 (2017)

More data for this
Ligand-Target Pair
UDP-3-O-acyl-GlcNAc deacetylase (LpxC)


(Pseudomonas aeruginosa)
BDBM264964
PNG
(US9718792, 101)
Show SMILES CCc1ccc(cc1F)C1=NO[C@@H](C[C@](C)(C(=O)NO)S(C)(=O)=O)C1
Show InChI InChI=1S/C16H21FN2O5S/c1-4-10-5-6-11(7-13(10)17)14-8-12(24-19-14)9-16(2,15(20)18-21)25(3,22)23/h5-7,12,21H,4,8-9H2,1-3H3,(H,18,20)/t12-,16-/m1/s1
PDB

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US Patent
n/an/a<0.00100n/an/an/an/a7.525



Novartis AG

US Patent


Assay Description
The P. aeruginosa LpxC protein is produced according to the general method of Hyland et al (Journal of Bacteriology 1997 179, 2029-2037: Cloning, exp...


US Patent US9718792 (2017)

More data for this
Ligand-Target Pair
UDP-3-O-acyl-GlcNAc deacetylase (LpxC)


(Pseudomonas aeruginosa)
BDBM264967
PNG
(US9718792, 102)
Show SMILES C[C@@](C[C@H]1CC(=NO1)c1ccc(c(F)c1)-c1ccc(CCO)cc1)(C(=O)NO)S(C)(=O)=O
Show InChI InChI=1S/C22H25FN2O6S/c1-22(21(27)24-28,32(2,29)30)13-17-12-20(25-31-17)16-7-8-18(19(23)11-16)15-5-3-14(4-6-15)9-10-26/h3-8,11,17,26,28H,9-10,12-13H2,1-2H3,(H,24,27)/t17-,22-/m1/s1
PDB

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n/an/a<0.00100n/an/an/an/a7.525



Novartis AG

US Patent


Assay Description
The P. aeruginosa LpxC protein is produced according to the general method of Hyland et al (Journal of Bacteriology 1997 179, 2029-2037: Cloning, exp...


US Patent US9718792 (2017)

More data for this
Ligand-Target Pair
UDP-3-O-acyl-GlcNAc deacetylase (LpxC)


(Pseudomonas aeruginosa)
BDBM264970
PNG
(US9718792, 103)
Show SMILES C[C@@](C[C@H]1CC(=NO1)c1ccc(c(F)c1)-c1ccc(CO)cc1)(C(=O)NO)S(C)(=O)=O
Show InChI InChI=1S/C21H23FN2O6S/c1-21(20(26)23-27,31(2,28)29)11-16-10-19(24-30-16)15-7-8-17(18(22)9-15)14-5-3-13(12-25)4-6-14/h3-9,16,25,27H,10-12H2,1-2H3,(H,23,26)/t16-,21-/m1/s1
PDB

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US Patent
n/an/a 0.00100n/an/an/an/a7.525



Novartis AG

US Patent


Assay Description
The P. aeruginosa LpxC protein is produced according to the general method of Hyland et al (Journal of Bacteriology 1997 179, 2029-2037: Cloning, exp...


US Patent US9718792 (2017)

More data for this
Ligand-Target Pair
UDP-3-O-acyl-GlcNAc deacetylase (LpxC)


(Pseudomonas aeruginosa)
BDBM264973
PNG
(US9718792, 104)
Show SMILES C[C@@](C[C@H]1CC(=NO1)c1ccc(c(F)c1)-c1ccc(CC#N)cc1)(C(=O)NO)S(C)(=O)=O
Show InChI InChI=1S/C22H22FN3O5S/c1-22(21(27)25-28,32(2,29)30)13-17-12-20(26-31-17)16-7-8-18(19(23)11-16)15-5-3-14(4-6-15)9-10-24/h3-8,11,17,28H,9,12-13H2,1-2H3,(H,25,27)/t17-,22-/m1/s1
PDB

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US Patent
n/an/a 0.00100n/an/an/an/a7.525



Novartis AG

US Patent


Assay Description
The P. aeruginosa LpxC protein is produced according to the general method of Hyland et al (Journal of Bacteriology 1997 179, 2029-2037: Cloning, exp...


US Patent US9718792 (2017)

More data for this
Ligand-Target Pair
UDP-3-O-acyl-GlcNAc deacetylase (LpxC)


(Pseudomonas aeruginosa)
BDBM264975
PNG
(US9718792, 105)
Show SMILES COc1ccc(cn1)-c1ccc(cc1F)C1=NO[C@@H](C[C@](C)(C(=O)NO)S(C)(=O)=O)C1
Show InChI InChI=1S/C20H22FN3O6S/c1-20(19(25)23-26,31(3,27)28)10-14-9-17(24-30-14)12-4-6-15(16(21)8-12)13-5-7-18(29-2)22-11-13/h4-8,11,14,26H,9-10H2,1-3H3,(H,23,25)/t14-,20-/m1/s1
PDB

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PC sid
UniChem
US Patent
n/an/a 0.00100n/an/an/an/a7.525



Novartis AG

US Patent


Assay Description
The P. aeruginosa LpxC protein is produced according to the general method of Hyland et al (Journal of Bacteriology 1997 179, 2029-2037: Cloning, exp...


US Patent US9718792 (2017)

More data for this
Ligand-Target Pair
UDP-3-O-acyl-GlcNAc deacetylase (LpxC)


(Pseudomonas aeruginosa)
BDBM264978
PNG
(US9718792, 107)
Show SMILES C[C@@H](O)Cc1ccc(cn1)-c1ccc(cc1F)C1=NO[C@@H](C[C@](C)(C(=O)NO)S(C)(=O)=O)C1
Show InChI InChI=1S/C22H26FN3O6S/c1-13(27)8-16-6-4-15(12-24-16)18-7-5-14(9-19(18)23)20-10-17(32-26-20)11-22(2,21(28)25-29)33(3,30)31/h4-7,9,12-13,17,27,29H,8,10-11H2,1-3H3,(H,25,28)/t13-,17-,22-/m1/s1
PDB

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UniProtKB/SwissProt

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PC sid
UniChem
US Patent
n/an/a 0.00100n/an/an/an/a7.525



Novartis AG

US Patent


Assay Description
The P. aeruginosa LpxC protein is produced according to the general method of Hyland et al (Journal of Bacteriology 1997 179, 2029-2037: Cloning, exp...


US Patent US9718792 (2017)

More data for this
Ligand-Target Pair
UDP-3-O-acyl-GlcNAc deacetylase (LpxC)


(Pseudomonas aeruginosa)
BDBM264987
PNG
(US9718792, 110)
Show SMILES CC(C)(O)c1ccc(cc1)-c1ccc(cc1F)C1=NO[C@@H](C[C@](C)(C(=O)NO)S(C)(=O)=O)C1
Show InChI InChI=1S/C23H27FN2O6S/c1-22(2,28)16-8-5-14(6-9-16)18-10-7-15(11-19(18)24)20-12-17(32-26-20)13-23(3,21(27)25-29)33(4,30)31/h5-11,17,28-29H,12-13H2,1-4H3,(H,25,27)/t17-,23-/m1/s1
PDB

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n/an/a<0.00100n/an/an/an/a7.525



Novartis AG

US Patent


Assay Description
The P. aeruginosa LpxC protein is produced according to the general method of Hyland et al (Journal of Bacteriology 1997 179, 2029-2037: Cloning, exp...


US Patent US9718792 (2017)

More data for this
Ligand-Target Pair
UDP-3-O-acyl-GlcNAc deacetylase (LpxC)


(Pseudomonas aeruginosa)
BDBM264990
PNG
(US9718792, 111)
Show SMILES C[C@@](C[C@H]1CC(=NO1)c1ccc(cc1)-c1ccncc1C(F)(F)F)(C(=O)NO)S(C)(=O)=O
Show InChI InChI=1S/C20H20F3N3O5S/c1-19(18(27)25-28,32(2,29)30)10-14-9-17(26-31-14)13-5-3-12(4-6-13)15-7-8-24-11-16(15)20(21,22)23/h3-8,11,14,28H,9-10H2,1-2H3,(H,25,27)/t14-,19-/m1/s1
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n/an/a<0.00100n/an/an/an/a7.525



Novartis AG

US Patent


Assay Description
The P. aeruginosa LpxC protein is produced according to the general method of Hyland et al (Journal of Bacteriology 1997 179, 2029-2037: Cloning, exp...


US Patent US9718792 (2017)

More data for this
Ligand-Target Pair
UDP-3-O-acyl-GlcNAc deacetylase (LpxC)


(Pseudomonas aeruginosa)
BDBM264993
PNG
(US9718792, 112)
Show SMILES CC(C)c1cc(ccn1)-c1ccc(cc1F)C1=NO[C@@H](C[C@](C)(C(=O)NO)S(C)(=O)=O)C1
Show InChI InChI=1S/C22H26FN3O5S/c1-13(2)19-10-14(7-8-24-19)17-6-5-15(9-18(17)23)20-11-16(31-26-20)12-22(3,21(27)25-28)32(4,29)30/h5-10,13,16,28H,11-12H2,1-4H3,(H,25,27)/t16-,22-/m1/s1
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n/an/a<0.00100n/an/an/an/a7.525



Novartis AG

US Patent


Assay Description
The P. aeruginosa LpxC protein is produced according to the general method of Hyland et al (Journal of Bacteriology 1997 179, 2029-2037: Cloning, exp...


US Patent US9718792 (2017)

More data for this
Ligand-Target Pair
UDP-3-O-acyl-GlcNAc deacetylase (LpxC)


(Pseudomonas aeruginosa)
BDBM264996
PNG
(US9718792, 113)
Show SMILES COc1ccc(c(C)c1)-c1ccc(cc1F)C1=NO[C@@H](C[C@](C)(C(=O)NO)S(C)(=O)=O)C1
Show InChI InChI=1S/C22H25FN2O6S/c1-13-9-15(30-3)6-8-17(13)18-7-5-14(10-19(18)23)20-11-16(31-25-20)12-22(2,21(26)24-27)32(4,28)29/h5-10,16,27H,11-12H2,1-4H3,(H,24,26)/t16-,22-/m1/s1
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n/an/a<0.00100n/an/an/an/a7.525



Novartis AG

US Patent


Assay Description
The P. aeruginosa LpxC protein is produced according to the general method of Hyland et al (Journal of Bacteriology 1997 179, 2029-2037: Cloning, exp...


US Patent US9718792 (2017)

More data for this
Ligand-Target Pair
UDP-3-O-acyl-GlcNAc deacetylase (LpxC)


(Pseudomonas aeruginosa)
BDBM264999
PNG
(US9718792, 114)
Show SMILES C[C@@](C[C@H]1CC(=NO1)c1ccc(c(F)c1)-c1ccc(cc1)-c1nn[nH]n1)(C(=O)NO)S(C)(=O)=O
Show InChI InChI=1S/C21H21FN6O5S/c1-21(20(29)25-30,34(2,31)32)11-15-10-18(26-33-15)14-7-8-16(17(22)9-14)12-3-5-13(6-4-12)19-23-27-28-24-19/h3-9,15,30H,10-11H2,1-2H3,(H,25,29)(H,23,24,27,28)/t15-,21-/m1/s1
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n/an/a<0.00100n/an/an/an/a7.525



Novartis AG

US Patent


Assay Description
The P. aeruginosa LpxC protein is produced according to the general method of Hyland et al (Journal of Bacteriology 1997 179, 2029-2037: Cloning, exp...


US Patent US9718792 (2017)

More data for this
Ligand-Target Pair
UDP-3-O-acyl-GlcNAc deacetylase (LpxC)


(Pseudomonas aeruginosa)
BDBM265002
PNG
(US9718792, 115)
Show SMILES C[C@@H](O)Cc1ccc(c(F)c1)-c1ccc(cc1F)C1=NO[C@@H](C[C@](C)(C(=O)NO)S(C)(=O)=O)C1
Show InChI InChI=1S/C23H26F2N2O6S/c1-13(28)8-14-4-6-17(19(24)9-14)18-7-5-15(10-20(18)25)21-11-16(33-27-21)12-23(2,22(29)26-30)34(3,31)32/h4-7,9-10,13,16,28,30H,8,11-12H2,1-3H3,(H,26,29)/t13-,16-,23-/m1/s1
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n/an/a<0.00100n/an/an/an/a7.525



Novartis AG

US Patent


Assay Description
The P. aeruginosa LpxC protein is produced according to the general method of Hyland et al (Journal of Bacteriology 1997 179, 2029-2037: Cloning, exp...


US Patent US9718792 (2017)

More data for this
Ligand-Target Pair
UDP-3-O-acyl-GlcNAc deacetylase (LpxC)


(Pseudomonas aeruginosa)
BDBM265005
PNG
(US9718792, 116)
Show SMILES C[C@@H](O)Cc1cc(F)c(c(F)c1)-c1ccc(cc1F)C1=NO[C@@H](C[C@](C)(C(=O)NO)S(C)(=O)=O)C1
Show InChI InChI=1S/C23H25F3N2O6S/c1-12(29)6-13-7-18(25)21(19(26)8-13)16-5-4-14(9-17(16)24)20-10-15(34-28-20)11-23(2,22(30)27-31)35(3,32)33/h4-5,7-9,12,15,29,31H,6,10-11H2,1-3H3,(H,27,30)/t12-,15-,23-/m1/s1
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n/an/a<0.00100n/an/an/an/a7.525



Novartis AG

US Patent


Assay Description
The P. aeruginosa LpxC protein is produced according to the general method of Hyland et al (Journal of Bacteriology 1997 179, 2029-2037: Cloning, exp...


US Patent US9718792 (2017)

More data for this
Ligand-Target Pair
UDP-3-O-acyl-GlcNAc deacetylase (LpxC)


(Pseudomonas aeruginosa)
BDBM265008
PNG
(US9718792, 117)
Show SMILES C[C@@](C[C@H]1CC(=NO1)c1ccc(c(F)c1)-c1ccncc1F)(C(=O)NO)S(C)(=O)=O
Show InChI InChI=1S/C19H19F2N3O5S/c1-19(18(25)23-26,30(2,27)28)9-12-8-17(24-29-12)11-3-4-13(15(20)7-11)14-5-6-22-10-16(14)21/h3-7,10,12,26H,8-9H2,1-2H3,(H,23,25)/t12-,19-/m1/s1
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n/an/a<0.00100n/an/an/an/a7.525



Novartis AG

US Patent


Assay Description
The P. aeruginosa LpxC protein is produced according to the general method of Hyland et al (Journal of Bacteriology 1997 179, 2029-2037: Cloning, exp...


US Patent US9718792 (2017)

More data for this
Ligand-Target Pair
UDP-3-O-acyl-GlcNAc deacetylase (LpxC)


(Pseudomonas aeruginosa)
BDBM265014
PNG
(US9718792, 119)
Show SMILES C[C@@](C[C@H]1CC(=NO1)c1ccc(cc1F)-c1ccncc1F)(C(=O)NO)S(C)(=O)=O
Show InChI InChI=1S/C19H19F2N3O5S/c1-19(18(25)23-26,30(2,27)28)9-12-8-17(24-29-12)14-4-3-11(7-15(14)20)13-5-6-22-10-16(13)21/h3-7,10,12,26H,8-9H2,1-2H3,(H,23,25)/t12-,19-/m1/s1
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n/an/a<0.00100n/an/an/an/a7.525



Novartis AG

US Patent


Assay Description
The P. aeruginosa LpxC protein is produced according to the general method of Hyland et al (Journal of Bacteriology 1997 179, 2029-2037: Cloning, exp...


US Patent US9718792 (2017)

More data for this
Ligand-Target Pair
UDP-3-O-acyl-GlcNAc deacetylase (LpxC)


(Pseudomonas aeruginosa)
BDBM265017
PNG
(US9718792, 120)
Show SMILES CCc1ccc(C2=NO[C@@H](C[C@](C)(C(=O)NO)S(C)(=O)=O)C2)c(F)c1
Show InChI InChI=1S/C16H21FN2O5S/c1-4-10-5-6-12(13(17)7-10)14-8-11(24-19-14)9-16(2,15(20)18-21)25(3,22)23/h5-7,11,21H,4,8-9H2,1-3H3,(H,18,20)/t11-,16-/m1/s1
PDB

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n/an/a 0.00100n/an/an/an/a7.525



Novartis AG

US Patent


Assay Description
The P. aeruginosa LpxC protein is produced according to the general method of Hyland et al (Journal of Bacteriology 1997 179, 2029-2037: Cloning, exp...


US Patent US9718792 (2017)

More data for this
Ligand-Target Pair
UDP-3-O-acyl-GlcNAc deacetylase (LpxC)


(Pseudomonas aeruginosa)
BDBM265020
PNG
(US9718792, 121)
Show SMILES C[C@@H](O)Cc1ccc(cc1)-c1ccc(cc1C)C1=NO[C@@H](C[C@](C)(C(=O)NO)S(C)(=O)=O)C1
Show InChI InChI=1S/C24H30N2O6S/c1-15-11-19(9-10-21(15)18-7-5-17(6-8-18)12-16(2)27)22-13-20(32-26-22)14-24(3,23(28)25-29)33(4,30)31/h5-11,16,20,27,29H,12-14H2,1-4H3,(H,25,28)/t16-,20-,24-/m1/s1
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n/an/a<0.00100n/an/an/an/a7.525



Novartis AG

US Patent


Assay Description
The P. aeruginosa LpxC protein is produced according to the general method of Hyland et al (Journal of Bacteriology 1997 179, 2029-2037: Cloning, exp...


US Patent US9718792 (2017)

More data for this
Ligand-Target Pair
UDP-3-O-acyl-GlcNAc deacetylase (LpxC)


(Pseudomonas aeruginosa)
BDBM265023
PNG
(US9718792, 122)
Show SMILES C[C@@H](O)Cc1ccc(cc1)-c1c(F)cc(cc1F)C1=NO[C@@H](C[C@](C)(C(=O)NO)S(C)(=O)=O)C1
Show InChI InChI=1S/C23H26F2N2O6S/c1-13(28)8-14-4-6-15(7-5-14)21-18(24)9-16(10-19(21)25)20-11-17(33-27-20)12-23(2,22(29)26-30)34(3,31)32/h4-7,9-10,13,17,28,30H,8,11-12H2,1-3H3,(H,26,29)/t13-,17-,23-/m1/s1
PDB

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n/an/a<0.00100n/an/an/an/a7.525



Novartis AG

US Patent


Assay Description
The P. aeruginosa LpxC protein is produced according to the general method of Hyland et al (Journal of Bacteriology 1997 179, 2029-2037: Cloning, exp...


US Patent US9718792 (2017)

More data for this
Ligand-Target Pair
UDP-3-O-acyl-GlcNAc deacetylase (LpxC)


(Pseudomonas aeruginosa)
BDBM265026
PNG
(US9718792, 123)
Show SMILES CC#Cc1ccc(C2=NO[C@@H](C[C@](C)(C(=O)NO)S(C)(=O)=O)C2)c(F)c1
Show InChI InChI=1S/C17H19FN2O5S/c1-4-5-11-6-7-13(14(18)8-11)15-9-12(25-20-15)10-17(2,16(21)19-22)26(3,23)24/h6-8,12,22H,9-10H2,1-3H3,(H,19,21)/t12-,17-/m1/s1
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Novartis AG

US Patent


Assay Description
The P. aeruginosa LpxC protein is produced according to the general method of Hyland et al (Journal of Bacteriology 1997 179, 2029-2037: Cloning, exp...


US Patent US9718792 (2017)

More data for this
Ligand-Target Pair
UDP-3-O-acyl-GlcNAc deacetylase (LpxC)


(Pseudomonas aeruginosa)
BDBM264720
PNG
(US9718792, 1-B)
Show SMILES CC(CC1CC(=NO1)c1ccc(Br)cc1)(C(=O)NO)S(C)(=O)=O
Show InChI InChI=1S/C14H17BrN2O5S/c1-14(13(18)16-19,23(2,20)21)8-11-7-12(17-22-11)9-3-5-10(15)6-4-9/h3-6,11,19H,7-8H2,1-2H3,(H,16,18)
PDB

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Novartis AG

US Patent


Assay Description
The P. aeruginosa LpxC protein is produced according to the general method of Hyland et al (Journal of Bacteriology 1997 179, 2029-2037: Cloning, exp...


US Patent US9718792 (2017)

More data for this
Ligand-Target Pair
UDP-3-O-acyl-GlcNAc deacetylase (LpxC)


(Pseudomonas aeruginosa)
BDBM264723
PNG
(US9718792, 2-A)
Show SMILES CC#Cc1ccc(cc1)C1=NO[C@@H](C[C@](C)(C(=O)NO)S(C)(=O)=O)C1
Show InChI InChI=1S/C17H20N2O5S/c1-4-5-12-6-8-13(9-7-12)15-10-14(24-19-15)11-17(2,16(20)18-21)25(3,22)23/h6-9,14,21H,10-11H2,1-3H3,(H,18,20)/t14-,17-/m1/s1
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Novartis AG

US Patent


Assay Description
The P. aeruginosa LpxC protein is produced according to the general method of Hyland et al (Journal of Bacteriology 1997 179, 2029-2037: Cloning, exp...


US Patent US9718792 (2017)

More data for this
Ligand-Target Pair
UDP-3-O-acyl-GlcNAc deacetylase (LpxC)


(Pseudomonas aeruginosa)
BDBM264726
PNG
(US9718792, 3-B)
Show SMILES CC(CC1CC(=NO1)c1ccc(cc1)-c1ccccc1)(C(=O)NO)S(C)(=O)=O
Show InChI InChI=1S/C20H22N2O5S/c1-20(19(23)21-24,28(2,25)26)13-17-12-18(22-27-17)16-10-8-15(9-11-16)14-6-4-3-5-7-14/h3-11,17,24H,12-13H2,1-2H3,(H,21,23)
PDB

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Novartis AG

US Patent


Assay Description
The P. aeruginosa LpxC protein is produced according to the general method of Hyland et al (Journal of Bacteriology 1997 179, 2029-2037: Cloning, exp...


US Patent US9718792 (2017)

More data for this
Ligand-Target Pair
UDP-3-O-acyl-GlcNAc deacetylase (LpxC)


(Pseudomonas aeruginosa)
BDBM264737
PNG
(US9718792, 6-A)
Show SMILES C[C@@](C[C@H]1CC(=NO1)c1ccc(cc1)C#CC1CC1)(C(=O)NO)S(C)(=O)=O
Show InChI InChI=1S/C19H22N2O5S/c1-19(18(22)20-23,27(2,24)25)12-16-11-17(21-26-16)15-9-7-14(8-10-15)6-5-13-3-4-13/h7-10,13,16,23H,3-4,11-12H2,1-2H3,(H,20,22)/t16-,19-/m1/s1
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Novartis AG

US Patent


Assay Description
The P. aeruginosa LpxC protein is produced according to the general method of Hyland et al (Journal of Bacteriology 1997 179, 2029-2037: Cloning, exp...


US Patent US9718792 (2017)

More data for this
Ligand-Target Pair
UDP-3-O-acyl-GlcNAc deacetylase (LpxC)


(Pseudomonas aeruginosa)
BDBM264740
PNG
(US9718792, 8-B)
Show SMILES CCC#Cc1ccc(cc1)C1=NOC(CC(C)(C(=O)NO)S(C)(=O)=O)C1
Show InChI InChI=1S/C18H22N2O5S/c1-4-5-6-13-7-9-14(10-8-13)16-11-15(25-20-16)12-18(2,17(21)19-22)26(3,23)24/h7-10,15,22H,4,11-12H2,1-3H3,(H,19,21)
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Novartis AG

US Patent


Assay Description
The P. aeruginosa LpxC protein is produced according to the general method of Hyland et al (Journal of Bacteriology 1997 179, 2029-2037: Cloning, exp...


US Patent US9718792 (2017)

More data for this
Ligand-Target Pair
UDP-3-O-acyl-GlcNAc deacetylase (LpxC)


(Pseudomonas aeruginosa)
BDBM264743
PNG
(US9718792, 10-B)
Show SMILES CC(CC1CC(=NO1)c1ccc(cc1)C#CCCO)(C(=O)NO)S(C)(=O)=O
Show InChI InChI=1S/C18H22N2O6S/c1-18(17(22)19-23,27(2,24)25)12-15-11-16(20-26-15)14-8-6-13(7-9-14)5-3-4-10-21/h6-9,15,21,23H,4,10-12H2,1-2H3,(H,19,22)
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Novartis AG

US Patent


Assay Description
The P. aeruginosa LpxC protein is produced according to the general method of Hyland et al (Journal of Bacteriology 1997 179, 2029-2037: Cloning, exp...


US Patent US9718792 (2017)

More data for this
Ligand-Target Pair
UDP-3-O-acyl-GlcNAc deacetylase (LpxC)


(Pseudomonas aeruginosa)
BDBM264749
PNG
(US9718792, 13-B)
Show SMILES CC(CC1CC(=NO1)c1ccc(C#CC2CC2)c(F)c1)(C(=O)NO)S(C)(=O)=O
Show InChI InChI=1S/C19H21FN2O5S/c1-19(18(23)21-24,28(2,25)26)11-15-10-17(22-27-15)14-8-7-13(16(20)9-14)6-5-12-3-4-12/h7-9,12,15,24H,3-4,10-11H2,1-2H3,(H,21,23)
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Novartis AG

US Patent


Assay Description
The P. aeruginosa LpxC protein is produced according to the general method of Hyland et al (Journal of Bacteriology 1997 179, 2029-2037: Cloning, exp...


US Patent US9718792 (2017)

More data for this
Ligand-Target Pair
UDP-3-O-acyl-GlcNAc deacetylase (LpxC)


(Pseudomonas aeruginosa)
BDBM264758
PNG
(US9718792, 16-B)
Show SMILES CC#Cc1ccc(C2=NOC(CC(C)(C(=O)NO)S(C)(=O)=O)C2)c(F)c1
Show InChI InChI=1S/C17H19FN2O5S/c1-4-5-11-6-7-13(14(18)8-11)15-9-12(25-20-15)10-17(2,16(21)19-22)26(3,23)24/h6-8,12,22H,9-10H2,1-3H3,(H,19,21)
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Novartis AG

US Patent


Assay Description
The P. aeruginosa LpxC protein is produced according to the general method of Hyland et al (Journal of Bacteriology 1997 179, 2029-2037: Cloning, exp...


US Patent US9718792 (2017)

More data for this
Ligand-Target Pair
UDP-3-O-acyl-GlcNAc deacetylase (LpxC)


(Pseudomonas aeruginosa)
BDBM264761
PNG
(US9718792, 17-B)
Show SMILES CC(CC1CC(=NO1)c1ccc(cc1F)C#CC1CC1)(C(=O)NO)S(C)(=O)=O
Show InChI InChI=1S/C19H21FN2O5S/c1-19(18(23)21-24,28(2,25)26)11-14-10-17(22-27-14)15-8-7-13(9-16(15)20)6-5-12-3-4-12/h7-9,12,14,24H,3-4,10-11H2,1-2H3,(H,21,23)
PDB

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n/an/a<0.00100n/an/an/an/a7.525



Novartis AG

US Patent


Assay Description
The P. aeruginosa LpxC protein is produced according to the general method of Hyland et al (Journal of Bacteriology 1997 179, 2029-2037: Cloning, exp...


US Patent US9718792 (2017)

More data for this
Ligand-Target Pair
UDP-3-O-acyl-GlcNAc deacetylase (LpxC)


(Pseudomonas aeruginosa)
BDBM264764
PNG
(US9718792, 22)
Show SMILES C[C@@](C[C@H]1CC(=NO1)c1ccc(cc1)C#CCCF)(C(=O)NO)S(C)(=O)=O
Show InChI InChI=1S/C18H21FN2O5S/c1-18(17(22)20-23,27(2,24)25)12-15-11-16(21-26-15)14-8-6-13(7-9-14)5-3-4-10-19/h6-9,15,23H,4,10-12H2,1-2H3,(H,20,22)/t15-,18-/m1/s1
PDB

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n/an/a<0.00100n/an/an/an/a7.525



Novartis AG

US Patent


Assay Description
The P. aeruginosa LpxC protein is produced according to the general method of Hyland et al (Journal of Bacteriology 1997 179, 2029-2037: Cloning, exp...


US Patent US9718792 (2017)

More data for this
Ligand-Target Pair
UDP-3-O-acyl-GlcNAc deacetylase (LpxC)


(Pseudomonas aeruginosa)
BDBM264767
PNG
(US9718792, 23)
Show SMILES CCCc1ccc(cc1)C1=NO[C@@H](C[C@](C)(C(=O)NO)S(C)(=O)=O)C1
Show InChI InChI=1S/C17H24N2O5S/c1-4-5-12-6-8-13(9-7-12)15-10-14(24-19-15)11-17(2,16(20)18-21)25(3,22)23/h6-9,14,21H,4-5,10-11H2,1-3H3,(H,18,20)/t14-,17-/m1/s1
PDB

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n/an/a<0.00100n/an/an/an/a7.525



Novartis AG

US Patent


Assay Description
The P. aeruginosa LpxC protein is produced according to the general method of Hyland et al (Journal of Bacteriology 1997 179, 2029-2037: Cloning, exp...


US Patent US9718792 (2017)

More data for this
Ligand-Target Pair
UDP-3-O-acyl-GlcNAc deacetylase (LpxC)


(Pseudomonas aeruginosa)
BDBM264770
PNG
(US9718792, 24)
Show SMILES C\C=C\c1ccc(cc1)C1=NO[C@@H](C[C@](C)(C(=O)NO)S(C)(=O)=O)C1
Show InChI InChI=1S/C17H22N2O5S/c1-4-5-12-6-8-13(9-7-12)15-10-14(24-19-15)11-17(2,16(20)18-21)25(3,22)23/h4-9,14,21H,10-11H2,1-3H3,(H,18,20)/b5-4+/t14-,17-/m1/s1
PDB

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n/an/a 0.00100n/an/an/an/a7.525



Novartis AG

US Patent


Assay Description
The P. aeruginosa LpxC protein is produced according to the general method of Hyland et al (Journal of Bacteriology 1997 179, 2029-2037: Cloning, exp...


US Patent US9718792 (2017)

More data for this
Ligand-Target Pair
UDP-3-O-acyl-GlcNAc deacetylase (LpxC)


(Pseudomonas aeruginosa)
BDBM264773
PNG
(US9718792, 29)
Show SMILES C\C=C(/F)c1ccc(cc1)C1=NO[C@@H](C[C@](C)(C(=O)NO)S(C)(=O)=O)C1
Show InChI InChI=1S/C17H21FN2O5S/c1-4-14(18)11-5-7-12(8-6-11)15-9-13(25-20-15)10-17(2,16(21)19-22)26(3,23)24/h4-8,13,22H,9-10H2,1-3H3,(H,19,21)/b14-4-/t13-,17-/m1/s1
PDB

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n/an/a 0.00100n/an/an/an/a7.525



Novartis AG

US Patent


Assay Description
The P. aeruginosa LpxC protein is produced according to the general method of Hyland et al (Journal of Bacteriology 1997 179, 2029-2037: Cloning, exp...


US Patent US9718792 (2017)

More data for this
Ligand-Target Pair
UDP-3-O-acyl-GlcNAc deacetylase (LpxC)


(Pseudomonas aeruginosa)
BDBM264776
PNG
(US9718792, 30)
Show SMILES CC(O)C#CC#Cc1ccc(cc1)C1=NO[C@@H](C[C@](C)(C(=O)NO)S(C)(=O)=O)C1
Show InChI InChI=1S/C20H22N2O6S/c1-14(23)6-4-5-7-15-8-10-16(11-9-15)18-12-17(28-22-18)13-20(2,19(24)21-25)29(3,26)27/h8-11,14,17,23,25H,12-13H2,1-3H3,(H,21,24)/t14?,17-,20-/m1/s1
PDB

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n/an/a 0.00100n/an/an/an/a7.525



Novartis AG

US Patent


Assay Description
The P. aeruginosa LpxC protein is produced according to the general method of Hyland et al (Journal of Bacteriology 1997 179, 2029-2037: Cloning, exp...


US Patent US9718792 (2017)

More data for this
Ligand-Target Pair
UDP-3-O-acyl-GlcNAc deacetylase (LpxC)


(Pseudomonas aeruginosa)
BDBM264779
PNG
(US9718792, 31)
Show SMILES CCc1ccc(cc1)C1=NO[C@@H](C[C@](C)(C(=O)NO)S(C)(=O)=O)C1
Show InChI InChI=1S/C16H22N2O5S/c1-4-11-5-7-12(8-6-11)14-9-13(23-18-14)10-16(2,15(19)17-20)24(3,21)22/h5-8,13,20H,4,9-10H2,1-3H3,(H,17,19)/t13-,16-/m1/s1
PDB

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n/an/a 0.00100n/an/an/an/a7.525



Novartis AG

US Patent


Assay Description
The P. aeruginosa LpxC protein is produced according to the general method of Hyland et al (Journal of Bacteriology 1997 179, 2029-2037: Cloning, exp...


US Patent US9718792 (2017)

More data for this
Ligand-Target Pair
UDP-3-O-acyl-GlcNAc deacetylase (LpxC)


(Pseudomonas aeruginosa)
BDBM264782
PNG
(US9718792, 32)
Show SMILES CCSc1ccc(cc1)C1=NO[C@@H](C[C@](C)(C(=O)NO)S(C)(=O)=O)C1
Show InChI InChI=1S/C16H22N2O5S2/c1-4-24-13-7-5-11(6-8-13)14-9-12(23-18-14)10-16(2,15(19)17-20)25(3,21)22/h5-8,12,20H,4,9-10H2,1-3H3,(H,17,19)/t12-,16-/m1/s1
PDB

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n/an/a 0.00100n/an/an/an/a7.525



Novartis AG

US Patent


Assay Description
The P. aeruginosa LpxC protein is produced according to the general method of Hyland et al (Journal of Bacteriology 1997 179, 2029-2037: Cloning, exp...


US Patent US9718792 (2017)

More data for this
Ligand-Target Pair
UDP-3-O-acyl-GlcNAc deacetylase (LpxC)


(Pseudomonas aeruginosa)
BDBM264791
PNG
(US9718792, 39A)
Show SMILES CC(C)(O)[C@H]1C[C@@H](C1)C#Cc1ccc(cc1)C1=NO[C@@H](C[C@](C)(C(=O)NO)S(C)(=O)=O)C1
Show InChI InChI=1S/C23H30N2O6S/c1-22(2,27)18-11-16(12-18)6-5-15-7-9-17(10-8-15)20-13-19(31-25-20)14-23(3,21(26)24-28)32(4,29)30/h7-10,16,18-19,27-28H,11-14H2,1-4H3,(H,24,26)/t16-,18-,19-,23-/m1/s1
PDB

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n/an/a 0.00100n/an/an/an/a7.525



Novartis AG

US Patent


Assay Description
The P. aeruginosa LpxC protein is produced according to the general method of Hyland et al (Journal of Bacteriology 1997 179, 2029-2037: Cloning, exp...


US Patent US9718792 (2017)

More data for this
Ligand-Target Pair
UDP-3-O-acyl-GlcNAc deacetylase (LpxC)


(Pseudomonas aeruginosa)
BDBM264797
PNG
(US9718792, 40)
Show SMILES C[C@@](C[C@H]1CC(=NO1)c1ccc(cc1)-c1ccc(CCO)cc1)(C(=O)NO)S(C)(=O)=O
Show InChI InChI=1S/C22H26N2O6S/c1-22(21(26)23-27,31(2,28)29)14-19-13-20(24-30-19)18-9-7-17(8-10-18)16-5-3-15(4-6-16)11-12-25/h3-10,19,25,27H,11-14H2,1-2H3,(H,23,26)/t19-,22-/m1/s1
PDB

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UniProtKB/SwissProt

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GoogleScholar
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PC sid
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US Patent
n/an/a 0.00100n/an/an/an/a7.525



Novartis AG

US Patent


Assay Description
The P. aeruginosa LpxC protein is produced according to the general method of Hyland et al (Journal of Bacteriology 1997 179, 2029-2037: Cloning, exp...


US Patent US9718792 (2017)

More data for this
Ligand-Target Pair
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