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Compile Data Set for Download or QSAR

Found 6 hits of ic50 data for polymerid = 50007331   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Glycogen phosphorylase, muscle form


(Rattus norvegicus)
BDBM50232903
PNG
(CHEMBL4067841)
Show SMILES Clc1ccc(CNC(=O)Cn2cccc(NC(=O)Nc3ccc(NC(=O)Nc4cccn(CC(=O)NCc5ccc(Cl)c(Cl)c5)c4=O)cc3)c2=O)cc1Cl
Show InChI InChI=1S/C36H30Cl4N8O6/c37-25-11-5-21(15-27(25)39)17-41-31(49)19-47-13-1-3-29(33(47)51)45-35(53)43-23-7-9-24(10-8-23)44-36(54)46-30-4-2-14-48(34(30)52)20-32(50)42-18-22-6-12-26(38)28(40)16-22/h1-16H,17-20H2,(H,41,49)(H,42,50)(H2,43,45,53)(H2,44,46,54)
PDB

UniProtKB/SwissProt

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PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 230n/an/an/an/an/an/a



Griffith University

Curated by ChEMBL


Assay Description
Inhibition of rat muscle glycogen phosphorylase A assessed as release of inorganic phosphate from glucose-1- phosphate in presence of glycogen after ...


Eur J Med Chem 127: 341-356 (2017)


Article DOI: 10.1016/j.ejmech.2016.12.049
More data for this
Ligand-Target Pair
Glycogen phosphorylase, muscle form


(Rattus norvegicus)
BDBM50232899
PNG
(CHEMBL4062976)
Show SMILES Clc1ccc(CNC(=O)Cn2cccc(NCc3ccc(CNc4cccn(CC(=O)NCc5ccc(Cl)c(Cl)c5)c4=O)s3)c2=O)cc1Cl
Show InChI InChI=1S/C34H30Cl4N6O4S/c35-25-9-5-21(13-27(25)37)15-41-31(45)19-43-11-1-3-29(33(43)47)39-17-23-7-8-24(49-23)18-40-30-4-2-12-44(34(30)48)20-32(46)42-16-22-6-10-26(36)28(38)14-22/h1-14,39-40H,15-20H2,(H,41,45)(H,42,46)
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 260n/an/an/an/an/an/a



Griffith University

Curated by ChEMBL


Assay Description
Inhibition of rat muscle glycogen phosphorylase A assessed as release of inorganic phosphate from glucose-1- phosphate in presence of glycogen after ...


Eur J Med Chem 127: 341-356 (2017)


Article DOI: 10.1016/j.ejmech.2016.12.049
More data for this
Ligand-Target Pair
Glycogen phosphorylase, muscle form


(Rattus norvegicus)
BDBM50232901
PNG
(CHEMBL4085509)
Show SMILES CCCNC(=O)Cn1cccc(NC(=O)Nc2ccc(NC(=O)Nc3cccn(CC(=O)NCCC)c3=O)cc2)c1=O
Show InChI InChI=1S/C28H34N8O6/c1-3-13-29-23(37)17-35-15-5-7-21(25(35)39)33-27(41)31-19-9-11-20(12-10-19)32-28(42)34-22-8-6-16-36(26(22)40)18-24(38)30-14-4-2/h5-12,15-16H,3-4,13-14,17-18H2,1-2H3,(H,29,37)(H,30,38)(H2,31,33,41)(H2,32,34,42)
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.60E+3n/an/an/an/an/an/a



Griffith University

Curated by ChEMBL


Assay Description
Inhibition of rat muscle glycogen phosphorylase A assessed as release of inorganic phosphate from glucose-1- phosphate in presence of glycogen after ...


Eur J Med Chem 127: 341-356 (2017)


Article DOI: 10.1016/j.ejmech.2016.12.049
More data for this
Ligand-Target Pair
Glycogen phosphorylase, muscle form


(Rattus norvegicus)
BDBM50232900
PNG
(CHEMBL4091486)
Show SMILES CCOC(=O)Cn1cccc(NC(=O)Nc2ccc(NC(=O)Nc3cccn(CC(=O)OCC)c3=O)cc2)c1=O
Show InChI InChI=1S/C26H28N6O8/c1-3-39-21(33)15-31-13-5-7-19(23(31)35)29-25(37)27-17-9-11-18(12-10-17)28-26(38)30-20-8-6-14-32(24(20)36)16-22(34)40-4-2/h5-14H,3-4,15-16H2,1-2H3,(H2,27,29,37)(H2,28,30,38)
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 3.10E+3n/an/an/an/an/an/a



Griffith University

Curated by ChEMBL


Assay Description
Inhibition of rat muscle glycogen phosphorylase A assessed as release of inorganic phosphate from glucose-1- phosphate in presence of glycogen after ...


Eur J Med Chem 127: 341-356 (2017)


Article DOI: 10.1016/j.ejmech.2016.12.049
More data for this
Ligand-Target Pair
Glycogen phosphorylase, muscle form


(Rattus norvegicus)
BDBM50232902
PNG
(CHEMBL4070568)
Show SMILES Clc1ccc(CNc2cccn(Cc3ccccc3)c2=O)cc1Cl
Show InChI InChI=1S/C19H16Cl2N2O/c20-16-9-8-15(11-17(16)21)12-22-18-7-4-10-23(19(18)24)13-14-5-2-1-3-6-14/h1-11,22H,12-13H2
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 3.30E+4n/an/an/an/an/an/a



Griffith University

Curated by ChEMBL


Assay Description
Inhibition of rat muscle glycogen phosphorylase A assessed as release of inorganic phosphate from glucose-1- phosphate in presence of glycogen after ...


Eur J Med Chem 127: 341-356 (2017)


Article DOI: 10.1016/j.ejmech.2016.12.049
More data for this
Ligand-Target Pair
Glycogen phosphorylase, muscle form


(Rattus norvegicus)
BDBM10849
PNG
(1,3,7-trimethyl-2,3,6,7-tetrahydro-1H-purine-2,6-d...)
Show SMILES Cn1cnc2n(C)c(=O)n(C)c(=O)c12
Show InChI InChI=1S/C8H10N4O2/c1-10-4-9-6-5(10)7(13)12(3)8(14)11(6)2/h4H,1-3H3
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KEGG
MMDB
PC cid
PC sid
PDB
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Patents


Similars

Article
PubMed
n/an/a 1.82E+5n/an/an/an/an/an/a



Griffith University

Curated by ChEMBL


Assay Description
Inhibition of rat muscle glycogen phosphorylase A assessed as release of inorganic phosphate from glucose-1- phosphate in presence of glycogen after ...


Eur J Med Chem 127: 341-356 (2017)


Article DOI: 10.1016/j.ejmech.2016.12.049
More data for this
Ligand-Target Pair