Compile Data Set for Download or QSAR
maximum 50k data
Found 32 of ic50 data for polymerid = 50007585,50006504,50007204
TargetSterol O-acyltransferase 1(Cricetulus griseus)
TBA

Curated by ChEMBL
LigandPNGBDBM50051901(1-[5-(4,5-Diphenyl-1H-imidazol-2-ylsulfanyl)-penty...)
Affinity DataIC50:  12nMAssay Description:Concentration required for the inhibition of Cholesterol O-acyl transferase from hamster liverMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSterol O-acyltransferase 1(Chlorocebus aethiops)
Tohoku Medical And Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50461446(CHEMBL4227742)
Affinity DataIC50:  230nMAssay Description:Inhibition of African green monkey SOAT1 isolated from CHO cell microsomes assessed as decrease in [14C]CE synthesis from [14C]oleic acid after 5 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Chlorocebus aethiops)
Tohoku Medical And Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50461446(CHEMBL4227742)
Affinity DataIC50:  780nMAssay Description:Inhibition of African green monkey SOAT1 expressed in CHO cells assessed as decrease in [14C]CE synthesis from [14C]oleic acid after 6 hrsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Chlorocebus aethiops)
Tohoku Medical And Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50281511(Acetic acid (S)-1-(11-hydroxy-4-methoxy-9-methyl-5...)
Affinity DataIC50:  900nMAssay Description:Inhibition of African green monkey SOAT1 expressed in CHO cell microsomal fractions assessed as reduction in neutral lipid synthesis incubated for 6 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Chlorocebus aethiops)
Tohoku Medical And Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50461447(CHEMBL4228016)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of African green monkey SOAT1 isolated from CHO cell microsomes assessed as decrease in [14C]CE synthesis from [14C]oleic acid after 5 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Chlorocebus aethiops)
Tohoku Medical And Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50360305(CHEMBL409855 | US9149492, Beauveriolide III)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of African green monkey SOAT1 expressed in CHO cells assessed as decrease in [14C]CE synthesis from [14C]oleic acid after 6 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Chlorocebus aethiops)
Tohoku Medical And Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50461447(CHEMBL4228016)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of African green monkey SOAT1 expressed in CHO cells assessed as decrease in [14C]CE synthesis from [14C]oleic acid after 6 hrsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Chlorocebus aethiops)
Tohoku Medical And Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50450891(CHEMBL4212280)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of African green monkey SOAT1 expressed in CHO cells assessed as reduction in neutral lipid synthesis incubated for 6 hrs using [1-14C]ole...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Chlorocebus aethiops)
Tohoku Medical And Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50450891(CHEMBL4212280)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of African green monkey SOAT1 expressed in CHO cell microsomal fractions assessed as reduction in neutral lipid synthesis incubated for 6 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Chlorocebus aethiops)
Tohoku Medical And Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50461448(CHEMBL4227559)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibition of African green monkey SOAT1 isolated from CHO cell microsomes assessed as decrease in [14C]CE synthesis from [14C]oleic acid after 5 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Chlorocebus aethiops)
Tohoku Medical And Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50281511(Acetic acid (S)-1-(11-hydroxy-4-methoxy-9-methyl-5...)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of African green monkey SOAT1 expressed in CHO cells assessed as reduction in neutral lipid synthesis incubated for 6 hrs using [1-14C]ole...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Chlorocebus aethiops)
Tohoku Medical And Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50360305(CHEMBL409855 | US9149492, Beauveriolide III)
Affinity DataIC50:  2.80E+3nMAssay Description:Inhibition of African green monkey SOAT1 isolated from CHO cell microsomes assessed as decrease in [14C]CE synthesis from [14C]oleic acid after 5 min...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Chlorocebus aethiops)
Tohoku Medical And Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50461448(CHEMBL4227559)
Affinity DataIC50:  5.20E+3nMAssay Description:Inhibition of African green monkey SOAT1 expressed in CHO cells assessed as decrease in [14C]CE synthesis from [14C]oleic acid after 6 hrsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Chlorocebus aethiops)
Tohoku Medical And Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50450893(CHEMBL4207391)
Affinity DataIC50:  6.80E+3nMAssay Description:Inhibition of African green monkey SOAT1 expressed in CHO cell microsomal fractions assessed as reduction in neutral lipid synthesis incubated for 6 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Chlorocebus aethiops)
Tohoku Medical And Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50450893(CHEMBL4207391)
Affinity DataIC50:  6.90E+3nMAssay Description:Inhibition of African green monkey SOAT1 expressed in CHO cells assessed as reduction in neutral lipid synthesis incubated for 6 hrs using [1-14C]ole...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Chlorocebus aethiops)
Tohoku Medical And Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50204547(CHEMBL3923673)
Affinity DataIC50:  8.90E+3nMAssay Description:Inhibition of African green monkey SOAT1 expressed in CHO cells assessed as reduction in [14C]cholesteryl ester formation from [1-14C]oleic acid meas...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Chlorocebus aethiops)
Tohoku Medical And Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50204553(CHEMBL3971022)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibition of African green monkey SOAT1 expressed in CHO cells assessed as reduction in [14C]cholesteryl ester formation from [1-14C]oleic acid meas...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Chlorocebus aethiops)
Tohoku Medical And Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50450892(CHEMBL4207917)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibition of African green monkey SOAT1 expressed in CHO cell microsomal fractions assessed as reduction in neutral lipid synthesis incubated for 6 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Chlorocebus aethiops)
Tohoku Medical And Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50450892(CHEMBL4207917)
Affinity DataIC50: >1.20E+4nMAssay Description:Inhibition of African green monkey SOAT1 expressed in CHO cells assessed as reduction in neutral lipid synthesis incubated for 6 hrs using [1-14C]ole...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Cricetulus griseus)
TBA

Curated by ChEMBL
LigandPNGBDBM50242257(2-((1R,2S,4aS)-1,2,4a,5-Tetramethyl-1,2,3,4,4a,7,8...)
Affinity DataIC50:  1.20E+4nMAssay Description:Inhibition of SOAT1 in CHO cell microsomal fraction using [1-14C]oleoyl-CoA as substrate measured after 5 mins by TLC based methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Chlorocebus aethiops)
Tohoku Medical And Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50204551(CHEMBL3958875)
Affinity DataIC50:  1.40E+4nMAssay Description:Inhibition of African green monkey SOAT1 expressed in CHO cells assessed as reduction in [14C]cholesteryl ester formation from [1-14C]oleic acid meas...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Chlorocebus aethiops)
Tohoku Medical And Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50242257(2-((1R,2S,4aS)-1,2,4a,5-Tetramethyl-1,2,3,4,4a,7,8...)
Affinity DataIC50:  1.42E+4nMAssay Description:Inhibition of African green monkey SOAT1 expressed in CHO cells using [1-14C]oleic acid incubated for 6 hrs by TLC based methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Chlorocebus aethiops)
Tohoku Medical And Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50204552(CHEMBL3959948)
Affinity DataIC50:  1.60E+4nMAssay Description:Inhibition of African green monkey SOAT1 expressed in CHO cells assessed as reduction in [14C]cholesteryl ester formation from [1-14C]oleic acid meas...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Chlorocebus aethiops)
Tohoku Medical And Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50196069(CHEMBL3965313)
Affinity DataIC50:  1.92E+4nMAssay Description:Inhibition of African green monkey SOAT1 expressed in CHO cells using [1-14C]oleic acid incubated for 6 hrs by TLC based methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Chlorocebus aethiops)
Tohoku Medical And Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50204548(CHEMBL3932453)
Affinity DataIC50: >2.20E+4nMAssay Description:Inhibition of African green monkey SOAT1 expressed in CHO cells assessed as reduction in [14C]cholesteryl ester formation from [1-14C]oleic acid meas...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Chlorocebus aethiops)
Tohoku Medical And Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50204558(CHEMBL3960874)
Affinity DataIC50: >2.30E+4nMAssay Description:Inhibition of African green monkey SOAT1 expressed in CHO cells assessed as reduction in [14C]cholesteryl ester formation from [1-14C]oleic acid meas...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Chlorocebus aethiops)
Tohoku Medical And Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50204556(CHEMBL3941429)
Affinity DataIC50: >2.70E+4nMAssay Description:Inhibition of African green monkey SOAT1 expressed in CHO cells assessed as reduction in [14C]cholesteryl ester formation from [1-14C]oleic acid meas...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Chlorocebus aethiops)
Tohoku Medical And Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50204550(CHEMBL3916935)
Affinity DataIC50: >2.80E+4nMAssay Description:Inhibition of African green monkey SOAT1 expressed in CHO cells assessed as reduction in [14C]cholesteryl ester formation from [1-14C]oleic acid meas...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Chlorocebus aethiops)
Tohoku Medical And Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50204545(CHEMBL3898917)
Affinity DataIC50: >2.80E+4nMAssay Description:Inhibition of African green monkey SOAT1 expressed in CHO cells assessed as reduction in [14C]cholesteryl ester formation from [1-14C]oleic acid meas...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Chlorocebus aethiops)
Tohoku Medical And Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50204555(CHEMBL3983935)
Affinity DataIC50: >3.10E+4nMAssay Description:Inhibition of African green monkey SOAT1 expressed in CHO cells assessed as reduction in [14C]cholesteryl ester formation from [1-14C]oleic acid meas...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Cricetulus griseus)
TBA

Curated by ChEMBL
LigandPNGBDBM50196069(CHEMBL3965313)
Affinity DataIC50:  3.20E+4nMAssay Description:Inhibition of SOAT1 in CHO cell microsomal fraction using [1-14C]oleoyl-CoA as substrate measured after 5 mins by TLC based methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA acetyltransferase, mitochondrial(Rattus norvegicus)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50346601(NSC-114945 | OLEANOLIC_ACID | Oleanolic acid | Ole...)
Affinity DataIC50:  7.79E+4nMAssay Description:Inhibition of rat liver microsomal ACATMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed