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Found 34 of ic50 data for polymerid = 5910
TargetCalpain-2 catalytic subunit(Homo sapiens (Human))
The University Of Adelaide

Curated by ChEMBL
LigandPNGBDBM50358153(CHEMBL1921830)
Affinity DataIC50:  30nMAssay Description:Inhibition of calpain-2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-2 catalytic subunit(Homo sapiens (Human))
The University Of Adelaide

Curated by ChEMBL
LigandPNGBDBM50358153(CHEMBL1921830)
Affinity DataIC50:  30nMAssay Description:Inhibition of CAPN2 using BODIPY-labeled casein substrate by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-2 catalytic subunit(Homo sapiens (Human))
The University Of Adelaide

Curated by ChEMBL
LigandPNGBDBM50284777(CHEMBL36969 | Z-Phe-Tyr(Bu)-H)
Affinity DataIC50:  80nMAssay Description:Compound was tested for its inhibitory activity against calpain 2More data for this Ligand-Target Pair
In DepthDetails Article
TargetCalpain-2 catalytic subunit(Homo sapiens (Human))
The University Of Adelaide

Curated by ChEMBL
LigandPNGBDBM50358152(CHEMBL1921829)
Affinity DataIC50:  85nMAssay Description:Inhibition of CAPN2 using BODIPY-labeled casein substrate by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-2 catalytic subunit(Homo sapiens (Human))
The University Of Adelaide

Curated by ChEMBL
LigandPNGBDBM50284776(CHEMBL36904 | Z-Phe-Tyr(Me)-H)
Affinity DataIC50:  104nMAssay Description:Compound was tested for its inhibitory activity against calpain 2More data for this Ligand-Target Pair
In DepthDetails Article
TargetCalpain-2 catalytic subunit(Homo sapiens (Human))
The University Of Adelaide

Curated by ChEMBL
LigandPNGBDBM50284780(CHEMBL36801 | Z-Phe-Phe-H)
Affinity DataIC50:  104nMAssay Description:Compound was tested for its inhibitory activity against Calpain 2More data for this Ligand-Target Pair
In DepthDetails Article
TargetCalpain-2 catalytic subunit(Homo sapiens (Human))
The University Of Adelaide

Curated by ChEMBL
LigandPNGBDBM23866(MDL28170 | Z-Val-Phe-CHO | benzyl N-[(1S)-2-methyl...)
Affinity DataIC50:  150nMpH: 7.5 T: 2°CAssay Description:Inhibition of m-calpain was assayed in the reaction buffer (50 mM Tris-HCl, 100 mM NaCl, 5 mM β-mercaptoethanol, and 1 mM EDTA, pH 7.5) with 50 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-2 catalytic subunit(Homo sapiens (Human))
The University Of Adelaide

Curated by ChEMBL
LigandPNGBDBM50358155(CHEMBL1921832)
Affinity DataIC50:  180nMAssay Description:Inhibition of CAPN2 using BODIPY-labeled casein substrate by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-2 catalytic subunit(Homo sapiens (Human))
The University Of Adelaide

Curated by ChEMBL
LigandPNGBDBM50084650(CHEMBL177914 | {(S)-1-[(S)-1-Formyl-2-(4-hydroxy-p...)
Affinity DataIC50:  184nMAssay Description:Inhibitory activity against Calpain 2Checked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-2 catalytic subunit(Homo sapiens (Human))
The University Of Adelaide

Curated by ChEMBL
LigandPNGBDBM50284779(CHEMBL36146 | Z-Phe-Tyr-H)
Affinity DataIC50:  184nMAssay Description:Compound was tested for its inhibitory activity against calpain 2More data for this Ligand-Target Pair
In DepthDetails Article
TargetCalpain-2 catalytic subunit(Homo sapiens (Human))
The University Of Adelaide

Curated by ChEMBL
LigandPNGBDBM50358148(CHEMBL1921825)
Affinity DataIC50:  280nMAssay Description:Inhibition of CAPN2 using BODIPY-labeled casein substrate by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-2 catalytic subunit(Homo sapiens (Human))
The University Of Adelaide

Curated by ChEMBL
LigandPNGBDBM50358157(CHEMBL1921834)
Affinity DataIC50:  295nMAssay Description:Inhibition of CAPN2 using BODIPY-labeled casein substrate by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-2 catalytic subunit(Homo sapiens (Human))
The University Of Adelaide

Curated by ChEMBL
LigandPNGBDBM110185(Z-FF-FMK | benzyl N-[1-[(4-fluoro-3-oxo-1-phenylbu...)
Affinity DataIC50:  418nMpH: 7.5 T: 2°CAssay Description:Inhibition of m-calpain was assayed in the reaction buffer (50 mM Tris-HCl, 100 mM NaCl, 5 mM β-mercaptoethanol, and 1 mM EDTA, pH 7.5) with 50 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-2 catalytic subunit(Homo sapiens (Human))
The University Of Adelaide

Curated by ChEMBL
LigandPNGBDBM50358154(CHEMBL1921831)
Affinity DataIC50:  700nMAssay Description:Inhibition of CAPN2 using BODIPY-labeled casein substrate by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-2 catalytic subunit(Homo sapiens (Human))
The University Of Adelaide

Curated by ChEMBL
LigandPNGBDBM50358150(CHEMBL1921827)
Affinity DataIC50:  850nMAssay Description:Inhibition of CAPN2 using BODIPY-labeled casein substrate by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-2 catalytic subunit(Homo sapiens (Human))
The University Of Adelaide

Curated by ChEMBL
LigandPNGBDBM50358158(CHEMBL1921835)
Affinity DataIC50:  1.01E+3nMAssay Description:Inhibition of CAPN2 using BODIPY-labeled casein substrate by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-2 catalytic subunit(Homo sapiens (Human))
The University Of Adelaide

Curated by ChEMBL
LigandPNGBDBM50358156(CHEMBL1921833)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of CAPN2 using BODIPY-labeled casein substrate by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-2 catalytic subunit(Homo sapiens (Human))
The University Of Adelaide

Curated by ChEMBL
LigandPNGBDBM50358149(CHEMBL1921826)
Affinity DataIC50:  2.40E+3nMAssay Description:Inhibition of CAPN2 using BODIPY-labeled casein substrate by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-2 catalytic subunit(Homo sapiens (Human))
The University Of Adelaide

Curated by ChEMBL
LigandPNGBDBM50358147(CHEMBL1921824)
Affinity DataIC50:  3.71E+3nMAssay Description:Inhibition of CAPN2 using BODIPY-labeled casein substrate by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-2 catalytic subunit(Homo sapiens (Human))
The University Of Adelaide

Curated by ChEMBL
LigandPNGBDBM110190(1-(2,4-Dihydroxyphenyl)-3-(furan-2-yl)propenone (1...)
Affinity DataIC50:  2.54E+4nMpH: 7.5 T: 2°CAssay Description:Inhibition of m-calpain was assayed in the reaction buffer (50 mM Tris-HCl, 100 mM NaCl, 5 mM β-mercaptoethanol, and 1 mM EDTA, pH 7.5) with 50 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-2 catalytic subunit(Homo sapiens (Human))
The University Of Adelaide

Curated by ChEMBL
LigandPNGBDBM50358159(CHEMBL1921836)
Affinity DataIC50:  2.80E+4nMAssay Description:Inhibition of CAPN2 using BODIPY-labeled casein substrate by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-2 catalytic subunit(Homo sapiens (Human))
The University Of Adelaide

Curated by ChEMBL
LigandPNGBDBM50358151(CHEMBL1921828)
Affinity DataIC50:  3.10E+4nMAssay Description:Inhibition of CAPN2 using BODIPY-labeled casein substrate by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-2 catalytic subunit(Homo sapiens (Human))
The University Of Adelaide

Curated by ChEMBL
LigandPNGBDBM110189(1-(2,4-Dihydroxyphenyl)-3-(thiophen-2-yl)propenone...)
Affinity DataIC50:  3.99E+4nMpH: 7.5 T: 2°CAssay Description:Inhibition of m-calpain was assayed in the reaction buffer (50 mM Tris-HCl, 100 mM NaCl, 5 mM β-mercaptoethanol, and 1 mM EDTA, pH 7.5) with 50 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-2 catalytic subunit(Homo sapiens (Human))
The University Of Adelaide

Curated by ChEMBL
LigandPNGBDBM110191(3-(2,4-Dihydroxyphenyl)-1-(thiophen-2-yl)propenone...)
Affinity DataIC50:  6.02E+4nMpH: 7.5 T: 2°CAssay Description:Inhibition of m-calpain was assayed in the reaction buffer (50 mM Tris-HCl, 100 mM NaCl, 5 mM β-mercaptoethanol, and 1 mM EDTA, pH 7.5) with 50 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-2 catalytic subunit(Homo sapiens (Human))
The University Of Adelaide

Curated by ChEMBL
LigandPNGBDBM110196(1-(3,5-Dihydroxyphenyl)-3-(thiophen-3-yl)propenone...)
Affinity DataIC50:  9.73E+4nMpH: 7.5 T: 2°CAssay Description:Inhibition of m-calpain was assayed in the reaction buffer (50 mM Tris-HCl, 100 mM NaCl, 5 mM β-mercaptoethanol, and 1 mM EDTA, pH 7.5) with 50 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-2 catalytic subunit(Homo sapiens (Human))
The University Of Adelaide

Curated by ChEMBL
LigandPNGBDBM16509((2S)-1-[(2S,3S)-3-methyl-2-{[(2S,3S)-3-(propylcarb...)
Affinity DataIC50: >1.00E+5nMpH: 7.5 T: 2°CAssay Description:Inhibition of m-calpain was assayed in the reaction buffer (50 mM Tris-HCl, 100 mM NaCl, 5 mM β-mercaptoethanol, and 1 mM EDTA, pH 7.5) with 50 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-2 catalytic subunit(Homo sapiens (Human))
The University Of Adelaide

Curated by ChEMBL
LigandPNGBDBM110186(1-(2,4-Dihydroxyphenyl)-3-(pyridin-4-yl)propenone ...)
Affinity DataIC50: >1.00E+5nMpH: 7.5 T: 2°CAssay Description:Inhibition of m-calpain was assayed in the reaction buffer (50 mM Tris-HCl, 100 mM NaCl, 5 mM β-mercaptoethanol, and 1 mM EDTA, pH 7.5) with 50 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-2 catalytic subunit(Homo sapiens (Human))
The University Of Adelaide

Curated by ChEMBL
LigandPNGBDBM110187(1-(2,4-Dihydroxyphenyl)-3-(pyridin-3-yl)propenone ...)
Affinity DataIC50: >1.00E+5nMpH: 7.5 T: 2°CAssay Description:Inhibition of m-calpain was assayed in the reaction buffer (50 mM Tris-HCl, 100 mM NaCl, 5 mM β-mercaptoethanol, and 1 mM EDTA, pH 7.5) with 50 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-2 catalytic subunit(Homo sapiens (Human))
The University Of Adelaide

Curated by ChEMBL
LigandPNGBDBM110188(1-(2,4-Dihydroxyphenyl)-3-(pyridin-2-yl)propenone ...)
Affinity DataIC50: >1.00E+5nMpH: 7.5 T: 2°CAssay Description:Inhibition of m-calpain was assayed in the reaction buffer (50 mM Tris-HCl, 100 mM NaCl, 5 mM β-mercaptoethanol, and 1 mM EDTA, pH 7.5) with 50 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-2 catalytic subunit(Homo sapiens (Human))
The University Of Adelaide

Curated by ChEMBL
LigandPNGBDBM110192(3-(2,4-Dihydroxyphenyl)-1-(furan-2-yl)propenone (1...)
Affinity DataIC50: >1.00E+5nMpH: 7.5 T: 2°CAssay Description:Inhibition of m-calpain was assayed in the reaction buffer (50 mM Tris-HCl, 100 mM NaCl, 5 mM β-mercaptoethanol, and 1 mM EDTA, pH 7.5) with 50 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-2 catalytic subunit(Homo sapiens (Human))
The University Of Adelaide

Curated by ChEMBL
LigandPNGBDBM110197(1-(3,5-Dihydroxyphenyl)-3-(furan-3-yl)propenone (2...)
Affinity DataIC50: >1.00E+5nMpH: 7.5 T: 2°CAssay Description:Inhibition of m-calpain was assayed in the reaction buffer (50 mM Tris-HCl, 100 mM NaCl, 5 mM β-mercaptoethanol, and 1 mM EDTA, pH 7.5) with 50 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCalpain-2 catalytic subunit(Homo sapiens (Human))
The University Of Adelaide

Curated by ChEMBL
LigandPNGBDBM110193(1-(3,5-Dihydroxyphenyl)-3-(thiophen-2-yl)propenone...)
Affinity DataIC50: >1.00E+5nMpH: 7.5 T: 2°CAssay Description:Inhibition of m-calpain was assayed in the reaction buffer (50 mM Tris-HCl, 100 mM NaCl, 5 mM β-mercaptoethanol, and 1 mM EDTA, pH 7.5) with 50 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-2 catalytic subunit(Homo sapiens (Human))
The University Of Adelaide

Curated by ChEMBL
LigandPNGBDBM110194(1-(3,5-Dihydroxyphenyl)-3-(furan-2-yl)propenone (2...)
Affinity DataIC50: >1.00E+5nMpH: 7.5 T: 2°CAssay Description:Inhibition of m-calpain was assayed in the reaction buffer (50 mM Tris-HCl, 100 mM NaCl, 5 mM β-mercaptoethanol, and 1 mM EDTA, pH 7.5) with 50 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCalpain-2 catalytic subunit(Homo sapiens (Human))
The University Of Adelaide

Curated by ChEMBL
LigandPNGBDBM110195(1-(3,5-Dihydroxyphenyl)-3-phenylpropenone (22))
Affinity DataIC50: >1.00E+5nMpH: 7.5 T: 2°CAssay Description:Inhibition of m-calpain was assayed in the reaction buffer (50 mM Tris-HCl, 100 mM NaCl, 5 mM β-mercaptoethanol, and 1 mM EDTA, pH 7.5) with 50 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed