Compile Data Set for Download or QSAR
maximum 50k data
Found 16 of ic50 data for polymerid = 8739
TargetInsulin-degrading enzyme(Mus musculus (Mouse))
Peking University Shenzhen Graduate School

Curated by ChEMBL
LigandPNGBDBM50459189(CHEMBL4211248)
Affinity DataIC50:  22nMAssay Description:Inhibition of mouse His-tagged IDE (42 to 1019 residues) using fluorophore/quencher-tagged RPPGFSAFK(Dnp)-OH peptide as substrate preincubated for 10...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetInsulin-degrading enzyme(Mus musculus (Mouse))
Peking University Shenzhen Graduate School

Curated by ChEMBL
LigandPNGBDBM50459187(CHEMBL4211765)
Affinity DataIC50:  44nMAssay Description:Inhibition of mouse His-tagged IDE (42 to 1019 residues) using fluorophore/quencher-tagged RPPGFSAFK(Dnp)-OH peptide as substrate preincubated for 10...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetInsulin-degrading enzyme(Mus musculus (Mouse))
Peking University Shenzhen Graduate School

Curated by ChEMBL
LigandPNGBDBM50525489(CHEMBL4556893)
Affinity DataIC50:  50nMAssay Description:Inhibition of N-terminal His6-tagged mouse recombinant IDE Escherichia coli BL21 (DE3) cells using fluorogenic peptide Mca-RPPGFSAFK(Dnp)-OH as subst...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-degrading enzyme(Mus musculus (Mouse))
Peking University Shenzhen Graduate School

Curated by ChEMBL
LigandPNGBDBM50459188(CHEMBL4206878)
Affinity DataIC50:  60nMAssay Description:Inhibition of mouse His-tagged IDE (42 to 1019 residues) using fluorophore/quencher-tagged RPPGFSAFK(Dnp)-OH peptide as substrate preincubated for 10...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInsulin-degrading enzyme(Mus musculus (Mouse))
Peking University Shenzhen Graduate School

Curated by ChEMBL
LigandPNGBDBM50459190(CHEMBL4208119)
Affinity DataIC50:  74nMAssay Description:Inhibition of mouse His-tagged IDE (42 to 1019 residues) using fluorophore/quencher-tagged RPPGFSAFK(Dnp)-OH peptide as substrate preincubated for 10...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInsulin-degrading enzyme(Mus musculus (Mouse))
Peking University Shenzhen Graduate School

Curated by ChEMBL
LigandPNGBDBM50459181(CHEMBL4207403)
Affinity DataIC50:  77nMAssay Description:Inhibition of mouse His-tagged IDE (42 to 1019 residues) using fluorophore/quencher-tagged RPPGFSAFK(Dnp)-OH peptide as substrate preincubated for 10...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInsulin-degrading enzyme(Mus musculus (Mouse))
Peking University Shenzhen Graduate School

Curated by ChEMBL
LigandPNGBDBM50459180(CHEMBL4203249)
Affinity DataIC50:  86nMAssay Description:Inhibition of mouse His-tagged IDE (42 to 1019 residues) using fluorophore/quencher-tagged RPPGFSAFK(Dnp)-OH peptide as substrate preincubated for 10...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInsulin-degrading enzyme(Mus musculus (Mouse))
Peking University Shenzhen Graduate School

Curated by ChEMBL
LigandPNGBDBM209045(US9243038, 20)
Affinity DataIC50:  90nMAssay Description:Macrocycles were assayed for IDE inhibition by monitoring cleavage of a substrate peptide containing a fluorophore-quencher pair such that cleavage o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInsulin-degrading enzyme(Mus musculus (Mouse))
Peking University Shenzhen Graduate School

Curated by ChEMBL
LigandPNGBDBM209032(US9243038, 6a (cis olefin) | US9243038, 6b (trans ...)
Affinity DataIC50:  90nMAssay Description:Macrocycles were assayed for IDE inhibition by monitoring cleavage of a substrate peptide containing a fluorophore-quencher pair such that cleavage o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInsulin-degrading enzyme(Mus musculus (Mouse))
Peking University Shenzhen Graduate School

Curated by ChEMBL
LigandPNGBDBM50459191(CHEMBL4215687)
Affinity DataIC50:  170nMAssay Description:Inhibition of mouse His-tagged IDE (42 to 1019 residues) using fluorophore/quencher-tagged RPPGFSAFK(Dnp)-OH peptide as substrate preincubated for 10...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetInsulin-degrading enzyme(Mus musculus (Mouse))
Peking University Shenzhen Graduate School

Curated by ChEMBL
LigandPNGBDBM50459182(CHEMBL4210721)
Affinity DataIC50:  230nMAssay Description:Inhibition of mouse His-tagged IDE (42 to 1019 residues) using fluorophore/quencher-tagged RPPGFSAFK(Dnp)-OH peptide as substrate preincubated for 10...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetInsulin-degrading enzyme(Mus musculus (Mouse))
Peking University Shenzhen Graduate School

Curated by ChEMBL
LigandPNGBDBM50459186(CHEMBL4216209)
Affinity DataIC50:  300nMAssay Description:Inhibition of mouse His-tagged IDE (42 to 1019 residues) using fluorophore/quencher-tagged RPPGFSAFK(Dnp)-OH peptide as substrate preincubated for 10...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetInsulin-degrading enzyme(Mus musculus (Mouse))
Peking University Shenzhen Graduate School

Curated by ChEMBL
LigandPNGBDBM50459184(CHEMBL4203477)
Affinity DataIC50:  601nMAssay Description:Inhibition of mouse His-tagged IDE (42 to 1019 residues) using fluorophore/quencher-tagged RPPGFSAFK(Dnp)-OH peptide as substrate preincubated for 10...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInsulin-degrading enzyme(Mus musculus (Mouse))
Peking University Shenzhen Graduate School

Curated by ChEMBL
LigandPNGBDBM50459183(CHEMBL4208342)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of mouse His-tagged IDE (42 to 1019 residues) using fluorophore/quencher-tagged RPPGFSAFK(Dnp)-OH peptide as substrate preincubated for 10...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInsulin-degrading enzyme(Mus musculus (Mouse))
Peking University Shenzhen Graduate School

Curated by ChEMBL
LigandPNGBDBM50459185(CHEMBL4204003)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of mouse His-tagged IDE (42 to 1019 residues) using fluorophore/quencher-tagged RPPGFSAFK(Dnp)-OH peptide as substrate preincubated for 10...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInsulin-degrading enzyme(Mus musculus (Mouse))
Peking University Shenzhen Graduate School

Curated by ChEMBL
LigandPNGBDBM50458054(Albac 50 | Baci-Rx | Baciferm 50 | Baciguent | Bac...)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of mouse His-tagged IDE (42 to 1019 residues) using fluorophore/quencher-tagged RPPGFSAFK(Dnp)-OH peptide as substrate preincubated for 10...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed