BindingDB PrimarySearch

Found 9 hits of kd data for polymerid = 2153,3627
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Serotonin (5-HT) receptor (Rattus norvegicus (rat))	BDBM86708 (CAS_146714-97-8 \| CHEMBL31354 \| CHEMBL514874 \| CHE...) Show SMILES Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	0.100	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by ChEMBL					Assay Description In vitro binding affinity for 5-hydroxytryptamine 1A receptor was determined by measuring specific inhibition of [125I]-binding to rat hippocampal me...				J Med Chem 41: 157-66 (1998) Article DOI: 10.1021/jm970296s BindingDB Entry DOI: 10.7270/Q2TX3DH6
University of Pennsylvania Curated by ChEMBL					More data for this Ligand-Target Pair
Serotonin (5-HT) receptor (Rattus norvegicus (rat))	BDBM50035508 (4-Iodo-N-{2-[4-(2-methoxy-phenyl)-piperazin-1-yl]-...) Show SMILES Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by ChEMBL					Assay Description The binding of [125I]MPPI ligand to 5-hydroxytryptamine 1A receptor of rat hippocampal homogenates				J Med Chem 37: 1406-7 (1994) Article DOI: 10.1021/jm00036a003 BindingDB Entry DOI: 10.7270/Q29Z95JQ
University of Pennsylvania Curated by ChEMBL					More data for this Ligand-Target Pair
Serotonin (5-HT) receptor (Rattus norvegicus (rat))	BDBM50007170 (Adamantane-1-carboxylic acid {4-[4-(2-methoxy-phen...) Show SMILES Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by ChEMBL					Assay Description Inhibition of binding of [125I]-8-OH-PIPAT ligand to 5-hydroxytryptamine 1A receptor of rat hippocampal homogenates				J Med Chem 37: 1406-7 (1994) Article DOI: 10.1021/jm00036a003 BindingDB Entry DOI: 10.7270/Q29Z95JQ
University of Pennsylvania Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (human))	BDBM50033383 ((S)-4-((3-(2-(dimethylamino)ethyl)-1H-indol-5-yl)m...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	1.80	n/a	n/a	n/a	n/a	n/a
Wellcome Research Laboratories Curated by ChEMBL					Assay Description Binding affinity against 5-hydroxytryptamine 1 receptor using rabbit jugular vein assay in the absence of endothelium				J Med Chem 38: 3566-80 (1995) Article DOI: 10.1021/jm00018a016 BindingDB Entry DOI: 10.7270/Q2GF0SJ4
Wellcome Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Serotonin (5-HT) receptor (Rattus norvegicus (rat))	BDBM21393 (7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-1-o...) Show SMILES CCCN(CCC)C1CCc2cccc(O)c2C1 Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	2.5	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Binding affinity against the site labelled by the 5-hydroxytryptamine 1A receptor agonist [3H]- 8-OH-DPAT				J Med Chem 37: 4346-51 (1995) Article DOI: 10.1021/jm00051a011 BindingDB Entry DOI: 10.7270/Q2HM57H0
Purdue University Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (human))	BDBM50423462 (CHEMBL251835) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	28	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for BioMedical Research Curated by ChEMBL					Assay Description Binding affinity to human 5HT1A receptor				Bioorg Med Chem Lett 18: 979-82 (2008) Article DOI: 10.1016/j.bmcl.2007.12.030 BindingDB Entry DOI: 10.7270/Q2WQ053B
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (human))	BDBM50034355 ((3aR,9bS)-3-Allyl-2,3,3a,4,5,9b-hexahydro-1H-benzo...) Show SMILES Oc1cccc2[C@@H]3CCN(CC=C)[C@@H]3CCc12 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Binding affinity to 5HT1A receptor				J Med Chem 52: 6107-25 (2009) Article DOI: 10.1021/jm901096y BindingDB Entry DOI: 10.7270/Q2J67HVQ
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (human))	BDBM50423465 (ERGOLINE) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for BioMedical Research Curated by ChEMBL					Assay Description Binding affinity to human 5HT1A receptor				Bioorg Med Chem Lett 18: 979-82 (2008) Article DOI: 10.1016/j.bmcl.2007.12.030 BindingDB Entry DOI: 10.7270/Q2WQ053B
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (human))	BDBM22416 ((3S,4R)-3-[(1,3-benzodioxol-5-yloxy)methyl]-4-(4-f...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Binding affinity to 5HT1A receptor				J Med Chem 52: 6107-25 (2009) Article DOI: 10.1021/jm901096y BindingDB Entry DOI: 10.7270/Q2J67HVQ
University of California Curated by ChEMBL					More data for this Ligand-Target Pair