Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Gag-Pol polyprotein (Human immunodeficiency virus type 1 group M subtyp...) | BDBM231619![]() (GSK5750) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | 387 | n/a | n/a | n/a | n/a | n/a |
McGill University | Assay Description In this case, 1 μM HIV-1 RT was added to 50 mM Tris-HCl (pH 7.8), 50 mM NaCl, 6 mM MgCl2, and varying concentrations of GSK5750 to form enzyme-i... | J Biol Chem 289: 16270-7 (2014) Article DOI: 10.1074/jbc.M114.569707 BindingDB Entry DOI: 10.7270/Q2MW2G0Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrase (Human immunodeficiency virus 1) | BDBM50163754![]() (CHEMBL1614842) | PDB B.MOAD GoogleScholar AffyNet ![]() | PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | n/a | 1.70E+5 | n/a | n/a | n/a | n/a | n/a |
Shandong University Curated by ChEMBL | Assay Description Binding affinity to HIV integrase | J Med Chem 59: 2849-78 (2016) Article DOI: 10.1021/acs.jmedchem.5b00497 BindingDB Entry DOI: 10.7270/Q2JH3P3H | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
Integrase (Human immunodeficiency virus 1) | BDBM50163753![]() (CHEMBL1615094) | PDB B.MOAD GoogleScholar AffyNet ![]() | PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | n/a | 2.80E+6 | n/a | n/a | n/a | n/a | n/a |
Shandong University Curated by ChEMBL | Assay Description Binding affinity to HIV integrase | J Med Chem 59: 2849-78 (2016) Article DOI: 10.1021/acs.jmedchem.5b00497 BindingDB Entry DOI: 10.7270/Q2JH3P3H | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
Integrase (Human immunodeficiency virus 1) | BDBM36291![]() (sesamol) | PDB B.MOAD GoogleScholar AffyNet ![]() | Purchase KEGG MMDB PC cid PC sid PDB UniChem | PDB Article PubMed | n/a | n/a | n/a | 5.50E+6 | n/a | n/a | n/a | n/a | n/a |
Shandong University Curated by ChEMBL | Assay Description Binding affinity to HIV integrase | J Med Chem 59: 2849-78 (2016) Article DOI: 10.1021/acs.jmedchem.5b00497 BindingDB Entry DOI: 10.7270/Q2JH3P3H | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) |