Compile Data Set for Download or QSAR
maximum 50k data
Found 134 of kd data for polymerid = 2711
TargetProtein-tyrosine kinase 6(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM26145(2,4-dianilino pyrimidine, 2 | 3-({4-[(5-hydroxy-2-...)
Affinity DataKd:  2nMAssay Description:Binding affinity to human BRKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-tyrosine kinase 6(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50273637(3-(4-amino-7-(piperidin-4-yl)-7H-pyrrolo[2,3-d]pyr...)
Affinity DataKd:  2nMAssay Description:Binding affinity to human BRKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-tyrosine kinase 6(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50355504(CHEMBL1908393)
Affinity DataKd:  4.30nMAssay Description:Binding constant for BRK kinase domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-tyrosine kinase 6(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM13216(BMS-354825 | CHEMBL1421 | DASATINIB | N-(2-Chloro-...)
Affinity DataKd:  7.80nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
TargetProtein-tyrosine kinase 6(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM13216(BMS-354825 | CHEMBL1421 | DASATINIB | N-(2-Chloro-...)
Affinity DataKd:  7.80nMAssay Description:Binding constant for BRK kinase domainMore data for this Ligand-Target Pair
TargetProtein-tyrosine kinase 6(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM13216(BMS-354825 | CHEMBL1421 | DASATINIB | N-(2-Chloro-...)
Affinity DataKd:  7.80nMAssay Description:Binding constant for PTK6 kinase domainMore data for this Ligand-Target Pair
TargetProtein-tyrosine kinase 6(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM21(CHEMBL24828 | N-(4-bromo-2-fluorophenyl)-6-methoxy...)
Affinity DataKd:  33nMAssay Description:Average Binding Constant for PTK6; NA=Not Active at 10 uMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-tyrosine kinase 6(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM482158(BDBM50242742 | TAE684)
Affinity DataKd:  36nMAssay Description:Binding constant for BRK kinase domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-tyrosine kinase 6(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM6568(6-(2,6-dichlorophenyl)-8-methyl-2-{[3-(methylsulfa...)
Affinity DataKd:  48nMAssay Description:Binding constant for BRK kinase domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-tyrosine kinase 6(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM25617(N-[3-({5-chloro-1H-pyrrolo[2,3-b]pyridin-3-yl}carb...)
Affinity DataKd:  48nMAssay Description:Binding constant for BRK kinase domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-tyrosine kinase 6(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50355494(CHEMBL1908396)
Affinity DataKd:  70nMAssay Description:Binding constant for BRK kinase domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-tyrosine kinase 6(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM21(CHEMBL24828 | N-(4-bromo-2-fluorophenyl)-6-methoxy...)
Affinity DataKd:  160nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetProtein-tyrosine kinase 6(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM21(CHEMBL24828 | N-(4-bromo-2-fluorophenyl)-6-methoxy...)
Affinity DataKd:  160nMAssay Description:Binding constant for PTK6 kinase domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-tyrosine kinase 6(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM21(CHEMBL24828 | N-(4-bromo-2-fluorophenyl)-6-methoxy...)
Affinity DataKd:  160nMAssay Description:Binding constant for BRK kinase domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-tyrosine kinase 6(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM60665(BDBM50249542 | US9145414, R406 | US9212178, R406)
Affinity DataKd:  360nMAssay Description:Binding constant for BRK kinase domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-tyrosine kinase 6(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50331096(4-(4-fluoro-2-methyl-1H-indol-5-yloxy)-6-methoxy-7...)
Affinity DataKd:  560nMAssay Description:Binding constant for BRK kinase domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-tyrosine kinase 6(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM24773(AMG 706 | AMG-706 | Motesanib | N-(3,3-dimethyl-1,...)
Affinity DataKd:  1.00E+3nMAssay Description:Binding constant for PTK6 kinase domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-tyrosine kinase 6(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM24773(AMG 706 | AMG-706 | Motesanib | N-(3,3-dimethyl-1,...)
Affinity DataKd:  1.00E+3nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetProtein-tyrosine kinase 6(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM36409(2-(4-amino-1-isopropyl-1H-pyrazolo[3,4-d]pyrimidin...)
Affinity DataKd:  1.00E+3nMAssay Description:Binding constant for BRK kinase domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-tyrosine kinase 6(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM24773(AMG 706 | AMG-706 | Motesanib | N-(3,3-dimethyl-1,...)
Affinity DataKd:  1.00E+3nMAssay Description:Binding constant for BRK kinase domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-tyrosine kinase 6(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM4779(CHEMBL31965 | CHEMBL545315 | CI-1033 | Canertinib ...)
Affinity DataKd:  1.10E+3nMAssay Description:Average Binding Constant for PTK6; NA=Not Active at 10 uMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-tyrosine kinase 6(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50332294(CHEMBL1287853 | N-tert-butyl-3-(5-methyl-2-(4-(2-(...)
Affinity DataKd:  1.20E+3nMAssay Description:Binding constant for BRK kinase domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-tyrosine kinase 6(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50308060(16-hydroxy-16-(hydroxymethyl)-15-methyl-28-oxa-4,1...)
Affinity DataKd:  1.70E+3nMAssay Description:Binding constant for BRK kinase domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-tyrosine kinase 6(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50308060(16-hydroxy-16-(hydroxymethyl)-15-methyl-28-oxa-4,1...)
Affinity DataKd:  1.70E+3nMAssay Description:Binding affinity to BRKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-tyrosine kinase 6(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)
Affinity DataKd:  2.30E+3nMAssay Description:Binding constant for PTK6 kinase domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-tyrosine kinase 6(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)
Affinity DataKd:  2.30E+3nMAssay Description:Binding constant for BRK kinase domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-tyrosine kinase 6(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM31096(CHEMBL290084 | Staurosporine | cid_451705)
Affinity DataKd:  2.30E+3nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetProtein-tyrosine kinase 6(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM26474(5-({4-[(2,3-dimethyl-2H-indazol-6-yl)(methyl)amino...)
Affinity DataKd:  2.30E+3nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetProtein-tyrosine kinase 6(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM26474(5-({4-[(2,3-dimethyl-2H-indazol-6-yl)(methyl)amino...)
Affinity DataKd:  2.30E+3nMAssay Description:Binding constant for PTK6 kinase domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-tyrosine kinase 6(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM26474(5-({4-[(2,3-dimethyl-2H-indazol-6-yl)(methyl)amino...)
Affinity DataKd:  2.30E+3nMAssay Description:Binding constant for BRK kinase domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-tyrosine kinase 6(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM4851((4-chlorophenyl)-[4-(4-pyridylmethyl)phthalazin-1-...)
Affinity DataKd:  2.40E+3nMAssay Description:Binding constant for PTK6 kinase domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-tyrosine kinase 6(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM4851((4-chlorophenyl)-[4-(4-pyridylmethyl)phthalazin-1-...)
Affinity DataKd:  2.40E+3nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetProtein-tyrosine kinase 6(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM4851((4-chlorophenyl)-[4-(4-pyridylmethyl)phthalazin-1-...)
Affinity DataKd:  2.40E+3nMAssay Description:Binding constant for BRK kinase domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-tyrosine kinase 6(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM4851((4-chlorophenyl)-[4-(4-pyridylmethyl)phthalazin-1-...)
Affinity DataKd:  2.70E+3nMAssay Description:Average Binding Constant for PTK6; NA=Not Active at 10 uMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-tyrosine kinase 6(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM13531(4-(4-Fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridy...)
Affinity DataKd:  3.00E+3nMAssay Description:Average Binding Constant for PTK6; NA=Not Active at 10 uMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-tyrosine kinase 6(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM31088(1-methyl-5-[2-[5-(trifluoromethyl)-1H-imidazol-2-y...)
Affinity DataKd:  3.60E+3nMAssay Description:Binding constant for BRK kinase domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-tyrosine kinase 6(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM31088(1-methyl-5-[2-[5-(trifluoromethyl)-1H-imidazol-2-y...)
Affinity DataKd:  3.60E+3nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetProtein-tyrosine kinase 6(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM31088(1-methyl-5-[2-[5-(trifluoromethyl)-1H-imidazol-2-y...)
Affinity DataKd:  3.60E+3nMAssay Description:Binding constant for PTK6 kinase domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-tyrosine kinase 6(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM4779(CHEMBL31965 | CHEMBL545315 | CI-1033 | Canertinib ...)
Affinity DataKd:  3.80E+3nMAssay Description:Binding constant for BRK kinase domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-tyrosine kinase 6(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM4779(CHEMBL31965 | CHEMBL545315 | CI-1033 | Canertinib ...)
Affinity DataKd:  3.80E+3nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetProtein-tyrosine kinase 6(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM4779(CHEMBL31965 | CHEMBL545315 | CI-1033 | Canertinib ...)
Affinity DataKd:  3.80E+3nMAssay Description:Binding constant for PTK6 kinase domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-tyrosine kinase 6(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM13336(4-[4-(4-fluorophenyl)-2-(4-methanesulfinylphenyl)-...)
Affinity DataKd:  3.90E+3nMAssay Description:Binding constant for BRK kinase domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-tyrosine kinase 6(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM13336(4-[4-(4-fluorophenyl)-2-(4-methanesulfinylphenyl)-...)
Affinity DataKd:  3.90E+3nMAssay Description:Binding constant for PTK6 kinase domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-tyrosine kinase 6(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM13336(4-[4-(4-fluorophenyl)-2-(4-methanesulfinylphenyl)-...)
Affinity DataKd:  3.90E+3nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetProtein-tyrosine kinase 6(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM4814(CHEMBL535 | N-[2-(diethylamino)ethyl]-5-[(Z)-(5-fl...)
Affinity DataKd:  4.60E+3nMAssay Description:Binding constant for BRK kinase domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-tyrosine kinase 6(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM25084(3-[2,4-diamino-6-(3-hydroxyphenyl)pteridin-7-yl]ph...)
Affinity DataKd:  5.00E+3nMAssay Description:Binding constant for BRK kinase domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-tyrosine kinase 6(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM13531(4-(4-Fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridy...)
Affinity DataKd:  6.80E+3nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetProtein-tyrosine kinase 6(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM13531(4-(4-Fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridy...)
Affinity DataKd:  6.80E+3nMAssay Description:Binding constant for PTK6 kinase domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-tyrosine kinase 6(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM13336(4-[4-(4-fluorophenyl)-2-(4-methanesulfinylphenyl)-...)
Affinity DataKd:  9.00E+3nMAssay Description:Average Binding Constant for PTK6; NA=Not Active at 10 uMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-tyrosine kinase 6(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM15244(5-(2,6-dichlorophenyl)-2-(2,4-difluorophenyl)sulfa...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for PTK6 kinase domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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