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Compile Data Set for Download or QSAR

Found 4 hits of kd data for polymerid = 50006908   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
DNA polymerase III subunit beta


(Escherichia coli (strain K12))
BDBM50096604
PNG
(CHEMBL3577290)
Show SMILES OC(=O)[C@H](Cc1ccccc1)NC(=O)Cn1c2C[C@@H](CCc2c2cc(Br)ccc12)C(O)=O
Show InChI InChI=1S/C24H23BrN2O5/c25-16-7-9-20-18(12-16)17-8-6-15(23(29)30)11-21(17)27(20)13-22(28)26-19(24(31)32)10-14-4-2-1-3-5-14/h1-5,7,9,12,15,19H,6,8,10-11,13H2,(H,26,28)(H,29,30)(H,31,32)/t15-,19+/m1/s1
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Article
PubMed
n/an/an/a 9.00E+3n/an/an/an/an/a



The University of Wollongong and The Illawarra Health and Medical Research Institute

Curated by ChEMBL


Assay Description
Binding affinity to Escherichia coli DNA sliding clamp protein at 298K by isothermal titration calorimetry


J Med Chem 58: 4693-702 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00232
BindingDB Entry DOI: 10.7270/Q2KK9DJ9
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
DNA polymerase III subunit beta


(Escherichia coli (strain K12))
BDBM50096605
PNG
(CHEMBL3577289)
Show SMILES OC(=O)[C@@H](Cc1ccccc1)NC(=O)Cn1c2C[C@@H](CCc2c2cc(Br)ccc12)C(O)=O
Show InChI InChI=1S/C24H23BrN2O5/c25-16-7-9-20-18(12-16)17-8-6-15(23(29)30)11-21(17)27(20)13-22(28)26-19(24(31)32)10-14-4-2-1-3-5-14/h1-5,7,9,12,15,19H,6,8,10-11,13H2,(H,26,28)(H,29,30)(H,31,32)/t15-,19-/m1/s1
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PubMed
n/an/an/a 1.30E+4n/an/an/an/an/a



The University of Wollongong and The Illawarra Health and Medical Research Institute

Curated by ChEMBL


Assay Description
Binding affinity to Escherichia coli DNA sliding clamp protein at 298K by isothermal titration calorimetry


J Med Chem 58: 4693-702 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00232
BindingDB Entry DOI: 10.7270/Q2KK9DJ9
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
DNA polymerase III subunit beta


(Escherichia coli (strain K12))
BDBM50096606
PNG
(CHEMBL3577279)
Show SMILES OC(=O)CNC(=O)Cn1c2C[C@@H](CCc2c2cc(Br)ccc12)C(O)=O
Show InChI InChI=1S/C17H17BrN2O5/c18-10-2-4-13-12(6-10)11-3-1-9(17(24)25)5-14(11)20(13)8-15(21)19-7-16(22)23/h2,4,6,9H,1,3,5,7-8H2,(H,19,21)(H,22,23)(H,24,25)/t9-/m1/s1
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PubMed
n/an/an/a 1.40E+4n/an/an/an/an/a



The University of Wollongong and The Illawarra Health and Medical Research Institute

Curated by ChEMBL


Assay Description
Binding affinity to Escherichia coli DNA sliding clamp protein at 298K by isothermal titration calorimetry


J Med Chem 58: 4693-702 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00232
BindingDB Entry DOI: 10.7270/Q2KK9DJ9
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
DNA polymerase III subunit beta


(Escherichia coli (strain K12))
BDBM50096607
PNG
(CHEMBL3577278)
Show SMILES OC(=O)CNC(=O)Cn1c2C[C@@H](CCc2c2cc(Cl)ccc12)C(O)=O
Show InChI InChI=1S/C17H17ClN2O5/c18-10-2-4-13-12(6-10)11-3-1-9(17(24)25)5-14(11)20(13)8-15(21)19-7-16(22)23/h2,4,6,9H,1,3,5,7-8H2,(H,19,21)(H,22,23)(H,24,25)/t9-/m1/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents


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Article
PubMed
n/an/an/a 2.40E+4n/an/an/an/an/a



The University of Wollongong and The Illawarra Health and Medical Research Institute

Curated by ChEMBL


Assay Description
Binding affinity to Escherichia coli DNA sliding clamp protein at 298K by isothermal titration calorimetry


J Med Chem 58: 4693-702 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00232
BindingDB Entry DOI: 10.7270/Q2KK9DJ9
More data for this
Ligand-Target Pair