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Compile Data Set for Download or QSAR

Found 670 hits of ki data for polymerid = 49000865   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Delta-type opioid receptor


(MOUSE)
BDBM50059997
PNG
(7 beta-Spirobenzocyclohexylnaltrexone | CHEMBL1016...)
Show SMILES Oc1ccc2CC3N(CC4CC4)CCC45[C@@H](Oc1c24)C(=O)[C@@]1(CCc2ccccc2C1)C[C@@]35O
Show InChI InChI=1S/C29H31NO4/c31-21-8-7-19-13-22-29(33)16-27(10-9-18-3-1-2-4-20(18)14-27)25(32)26-28(29,23(19)24(21)34-26)11-12-30(22)15-17-5-6-17/h1-4,7-8,17,22,26,31,33H,5-6,9-16H2/t22?,26-,27+,28?,29+/m0/s1
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0.00190n/an/an/an/an/an/an/an/a



University of Minnesota

Curated by ChEMBL


Assay Description
Inhibition of [3H]-NTI binding to Opioid receptor delta 1 from mouse brain membranes.


J Med Chem 40: 3064-70 (1997)


Article DOI: 10.1021/jm970283e
BindingDB Entry DOI: 10.7270/Q27D2T7R
More data for this
Ligand-Target Pair
Delta-type opioid receptor


(MOUSE)
BDBM50059994
PNG
(7 alpha-Spirobenzocyclohexylnaltrexone | CHEMBL105...)
Show SMILES Oc1ccc2CC3N(CC4CC4)CCC45[C@@H](Oc1c24)C(=O)[C@]1(CCc2ccccc2C1)C[C@@]35O
Show InChI InChI=1S/C29H31NO4/c31-21-8-7-19-13-22-29(33)16-27(10-9-18-3-1-2-4-20(18)14-27)25(32)26-28(29,23(19)24(21)34-26)11-12-30(22)15-17-5-6-17/h1-4,7-8,17,22,26,31,33H,5-6,9-16H2/t22?,26-,27-,28?,29+/m0/s1
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0.00410n/an/an/an/an/an/an/an/a



University of Minnesota

Curated by ChEMBL


Assay Description
Inhibition of [3H]-NTI binding to Opioid receptor delta 1 from mouse brain membranes.


J Med Chem 40: 3064-70 (1997)


Article DOI: 10.1021/jm970283e
BindingDB Entry DOI: 10.7270/Q27D2T7R
More data for this
Ligand-Target Pair
Delta-type opioid receptor


(MOUSE)
BDBM50058154
PNG
(7-(4'-Methoxy-2'-spiroindanyl)naltrexone | CHEMBL2...)
Show SMILES COc1cccc2CC3(Cc12)C[C@@]1(O)C2Cc4ccc(O)c5OC(C3=O)C1(CCN2CC1CC1)c45
Show InChI InChI=1S/C29H31NO5/c1-34-21-4-2-3-18-12-27(13-19(18)21)15-29(33)22-11-17-7-8-20(31)24-23(17)28(29,26(35-24)25(27)32)9-10-30(22)14-16-5-6-16/h2-4,7-8,16,22,26,31,33H,5-6,9-15H2,1H3/t22?,26?,27?,28?,29-/m1/s1
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0.0280n/an/an/an/an/an/an/an/a



University of Minnesota

Curated by ChEMBL


Assay Description
The compound tested for agonistic activity against Opioid receptor delta 1 using [3H]- NT1 as the radioligand.


J Med Chem 40: 1720-5 (1997)


Article DOI: 10.1021/jm9700880
BindingDB Entry DOI: 10.7270/Q2FB53M9
More data for this
Ligand-Target Pair
Delta-type opioid receptor


(MOUSE)
BDBM50370067
PNG
(CHEMBL1237164)
Show SMILES Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)c1[nH]c2ccccc2c1C[C@@]35O
Show InChI InChI=1S/C26H26N2O3/c29-19-8-7-15-11-20-26(30)12-17-16-3-1-2-4-18(16)27-22(17)24-25(26,21(15)23(19)31-24)9-10-28(20)13-14-5-6-14/h1-4,7-8,14,20,24,27,29-30H,5-6,9-13H2/t20-,24+,25+,26-/m1/s1
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0.0300n/an/an/an/an/an/an/an/a



National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL


Assay Description
Antagonist activity of compound on agonist stimulated [35S]GTP-gamma-S binding on delta-opioid receptor


J Med Chem 44: 1471-4 (2001)


Article DOI: 10.1021/jm000511w
BindingDB Entry DOI: 10.7270/Q2PK0GVP
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Delta-type opioid receptor


(MOUSE)
BDBM21864
PNG
((21R)-22-(cyclopropylmethyl)-14-oxa-11,22-diazahep...)
Show SMILES Oc1ccc2C[C@H]3N(CC4CC4)CCC45C(Oc1c24)c1[nH]c2ccccc2c1CC35O
Show InChI InChI=1S/C26H26N2O3/c29-19-8-7-15-11-20-26(30)12-17-16-3-1-2-4-18(16)27-22(17)24-25(26,21(15)23(19)31-24)9-10-28(20)13-14-5-6-14/h1-4,7-8,14,20,24,27,29-30H,5-6,9-13H2/t20-,24?,25?,26?/m0/s1
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0.0400n/an/an/an/an/an/an/an/a



University of Minnesota

Curated by ChEMBL


Assay Description
Binding affinity against Opioid receptor delta 1 receptor binding in ICR mouse brain membranes using the radioligand [3H]naltrindole


J Med Chem 40: 1977-81 (1997)


Article DOI: 10.1021/jm970189y
BindingDB Entry DOI: 10.7270/Q2J38T7Q
More data for this
Ligand-Target Pair
Delta-type opioid receptor


(MOUSE)
BDBM50391602
PNG
(CHEMBL2147915)
Show SMILES CN1CC[C@]23Cc4nc5c(O)cccc5cc4C[C@@]2(O)[C@H]1Cc1ccc(O)cc31
Show InChI InChI=1S/C24H24N2O3/c1-26-8-7-23-13-19-16(9-15-3-2-4-20(28)22(15)25-19)12-24(23,29)21(26)10-14-5-6-17(27)11-18(14)23/h2-6,9,11,21,27-29H,7-8,10,12-13H2,1H3/t21-,23-,24-/m1/s1
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0.0920n/an/an/an/an/an/an/an/a



Kitasato University

Curated by ChEMBL


Assay Description
Displacement of [3H]DPDPE from delta opioid receptor in mouse whole brain without cerebellum


Bioorg Med Chem 20: 5810-31 (2012)


Article DOI: 10.1016/j.bmc.2012.08.004
BindingDB Entry DOI: 10.7270/Q2F190T5
More data for this
Ligand-Target Pair
Delta-type opioid receptor


(MOUSE)
BDBM50253136
PNG
(CHEMBL4075409)
Show SMILES Oc1ccc2CC3N(CC=C)CCC4(C5[C@H]6CN(C5CCC34O6)C(=O)c3ccccc3)c2c1
Show InChI InChI=1S/C28H30N2O3/c1-2-13-29-14-12-27-21-16-20(31)9-8-19(21)15-24(29)28(27)11-10-22-25(27)23(33-28)17-30(22)26(32)18-6-4-3-5-7-18/h2-9,16,22-25,31H,1,10-15,17H2/t22?,23-,24?,25?,27?,28?/m1/s1
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0.109n/an/an/an/an/an/an/an/a



Kitasato University

Curated by ChEMBL


Assay Description
Displacement of [3H]DPDPE from delta opioid receptor in mouse whole brain without cerebellum membrane


Bioorg Med Chem Lett 27: 2742-2745 (2017)

More data for this
Ligand-Target Pair
Delta-type opioid receptor


(MOUSE)
BDBM50360146
PNG
(CHEMBL1929368)
Show SMILES Oc1ccc2C[C@@H]3[C@@H]4Cc5cc6ccccc6nc5C[C@]4(CCN3CC3CCC3)c2c1
Show InChI InChI=1S/C28H30N2O/c31-22-9-8-19-14-27-24-13-21-12-20-6-1-2-7-25(20)29-26(21)16-28(24,23(19)15-22)10-11-30(27)17-18-4-3-5-18/h1-2,6-9,12,15,18,24,27,31H,3-5,10-11,13-14,16-17H2/t24-,27+,28+/m0/s1
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0.120n/an/an/an/an/an/an/an/a



Kitasato University

Curated by ChEMBL


Assay Description
Displacement of [3H]DPDPE from delta opioid receptor in mouse whole brain membranes without cerebellum


Bioorg Med Chem 20: 949-61 (2012)


Article DOI: 10.1016/j.bmc.2011.11.047
BindingDB Entry DOI: 10.7270/Q2H995MX
More data for this
Ligand-Target Pair
Delta-type opioid receptor


(MOUSE)
BDBM50329100
PNG
(CHEMBL1270475)
Show SMILES Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]4(Cc5nc6ccccc6cc5C[C@@]34O)c2c1
Show InChI InChI=1S/C27H28N2O2/c30-21-8-7-18-12-25-27(31)14-20-11-19-3-1-2-4-23(19)28-24(20)15-26(27,22(18)13-21)9-10-29(25)16-17-5-6-17/h1-4,7-8,11,13,17,25,30-31H,5-6,9-10,12,14-16H2/t25-,26-,27-/m1/s1
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0.140n/an/an/an/an/an/an/an/a



Kitasato University

Curated by ChEMBL


Assay Description
Displacement of [3H]DPDPE from delta opioid receptor in mouse whole brain membranes


Bioorg Med Chem Lett 20: 6302-5 (2010)


Article DOI: 10.1016/j.bmcl.2010.08.083
BindingDB Entry DOI: 10.7270/Q2G73DZ1
More data for this
Ligand-Target Pair
Delta-type opioid receptor


(MOUSE)
BDBM50294428
PNG
(CHEMBL552308 | SN-28)
Show SMILES CN1CC[C@]23Cc4nc5ccccc5cc4C[C@H]2[C@H]1Cc1ccc(O)cc31
Show InChI InChI=1S/C24H24N2O/c1-26-9-8-24-14-22-17(10-16-4-2-3-5-21(16)25-22)11-20(24)23(26)12-15-6-7-18(27)13-19(15)24/h2-7,10,13,20,23,27H,8-9,11-12,14H2,1H3/t20-,23+,24+/m0/s1
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0.140n/an/an/an/an/an/an/an/a



Kitasato University

Curated by ChEMBL


Assay Description
Displacement of [3H]DPDPE from delta opioid receptor in mouse whole brain membranes


Bioorg Med Chem Lett 20: 6302-5 (2010)


Article DOI: 10.1016/j.bmcl.2010.08.083
BindingDB Entry DOI: 10.7270/Q2G73DZ1
More data for this
Ligand-Target Pair
Opioid receptors; mu and delta


(MOUSE)
BDBM50494888
PNG
(CHEMBL4296733)
Show SMILES Cl.Cl.CCN1CC[C@]23Cc4nc5ccccc5cc4C[C@@]2(O)[C@H]1Cc1ccc(O)cc31
Show InChI InChI=1S/C25H26N2O2.2ClH/c1-2-27-10-9-24-15-22-18(11-17-5-3-4-6-21(17)26-22)14-25(24,29)23(27)12-16-7-8-19(28)13-20(16)24;;/h3-8,11,13,23,28-29H,2,9-10,12,14-15H2,1H3;2*1H/t23-,24-,25-;;/m1../s1
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0.141n/an/an/an/an/an/an/an/a



Kitasato University

Curated by ChEMBL


Assay Description
Displacement of [3H]-DPDPE from delta opioid receptor in mouse whole brain membranes without cerebellum after 1 hr by liquid scintillation counting a...


Bioorg Med Chem 21: 7628-47 (2013)

More data for this
Ligand-Target Pair
Delta-type opioid receptor


(MOUSE)
BDBM50391591
PNG
(CHEMBL2147904)
Show SMILES CN1CC[C@]23Cc4nc5cccc(F)c5cc4C[C@@]2(O)[C@H]1Cc1ccc(O)cc31
Show InChI InChI=1S/C24H23FN2O2/c1-27-8-7-23-13-21-15(9-17-19(25)3-2-4-20(17)26-21)12-24(23,29)22(27)10-14-5-6-16(28)11-18(14)23/h2-6,9,11,22,28-29H,7-8,10,12-13H2,1H3/t22-,23-,24-/m1/s1
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0.143n/an/an/an/an/an/an/an/a



Kitasato University

Curated by ChEMBL


Assay Description
Displacement of [3H]DPDPE from delta opioid receptor in mouse whole brain without cerebellum


Bioorg Med Chem 20: 5810-31 (2012)


Article DOI: 10.1016/j.bmc.2012.08.004
BindingDB Entry DOI: 10.7270/Q2F190T5
More data for this
Ligand-Target Pair
Opioid receptors; mu and delta


(MOUSE)
BDBM50329100
PNG
(CHEMBL1270475)
Show SMILES Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]4(Cc5nc6ccccc6cc5C[C@@]34O)c2c1
Show InChI InChI=1S/C27H28N2O2/c30-21-8-7-18-12-25-27(31)14-20-11-19-3-1-2-4-23(19)28-24(20)15-26(27,22(18)13-21)9-10-29(25)16-17-5-6-17/h1-4,7-8,11,13,17,25,30-31H,5-6,9-10,12,14-16H2/t25-,26-,27-/m1/s1
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0.143n/an/an/an/an/an/an/an/a



Kitasato University

Curated by ChEMBL


Assay Description
Displacement of [3H]-DPDPE from delta opioid receptor in mouse whole brain membranes without cerebellum after 1 hr by liquid scintillation counting a...


Bioorg Med Chem 21: 7628-47 (2013)

More data for this
Ligand-Target Pair
Delta-type opioid receptor


(MOUSE)
BDBM50391594
PNG
(CHEMBL2147907)
Show SMILES CN1CC[C@]23Cc4nc5c(F)cccc5cc4C[C@@]2(O)[C@H]1Cc1ccc(O)cc31
Show InChI InChI=1S/C24H23FN2O2/c1-27-8-7-23-13-20-16(9-15-3-2-4-19(25)22(15)26-20)12-24(23,29)21(27)10-14-5-6-17(28)11-18(14)23/h2-6,9,11,21,28-29H,7-8,10,12-13H2,1H3/t21-,23-,24-/m1/s1
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0.146n/an/an/an/an/an/an/an/a



Kitasato University

Curated by ChEMBL


Assay Description
Displacement of [3H]DPDPE from delta opioid receptor in mouse whole brain without cerebellum


Bioorg Med Chem 20: 5810-31 (2012)


Article DOI: 10.1016/j.bmc.2012.08.004
BindingDB Entry DOI: 10.7270/Q2F190T5
More data for this
Ligand-Target Pair
Delta-type opioid receptor


(MOUSE)
BDBM50391595
PNG
(CHEMBL2147908)
Show SMILES CN1CC[C@]23Cc4nc5cccc(C)c5cc4C[C@@]2(O)[C@H]1Cc1ccc(O)cc31
Show InChI InChI=1S/C25H26N2O2/c1-15-4-3-5-21-19(15)10-17-13-25(29)23-11-16-6-7-18(28)12-20(16)24(25,8-9-27(23)2)14-22(17)26-21/h3-7,10,12,23,28-29H,8-9,11,13-14H2,1-2H3/t23-,24-,25-/m1/s1
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0.148n/an/an/an/an/an/an/an/a



Kitasato University

Curated by ChEMBL


Assay Description
Displacement of [3H]DPDPE from delta opioid receptor in mouse whole brain without cerebellum


Bioorg Med Chem 20: 5810-31 (2012)


Article DOI: 10.1016/j.bmc.2012.08.004
BindingDB Entry DOI: 10.7270/Q2F190T5
More data for this
Ligand-Target Pair
Opioid receptors; mu and delta


(MOUSE)
BDBM50491882
PNG
(CHEMBL3215908)
Show SMILES Cl.Cl.Oc1ccc2C[C@H]3N(CC4CC4)CC[C@]45[C@@H](Oc1c24)[C@@]1(O)CC[C@@]35N[C@H]1CC(=O)NCc1ccccc1
Show InChI InChI=1S/C30H35N3O4.2ClH/c34-21-9-8-20-14-23-30-11-10-29(36,22(32-30)15-24(35)31-16-18-4-2-1-3-5-18)27-28(30,25(20)26(21)37-27)12-13-33(23)17-19-6-7-19;;/h1-5,8-9,19,22-23,27,32,34,36H,6-7,10-17H2,(H,31,35);2*1H/t22-,23+,27+,28+,29+,30+;;/m0../s1
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0.150n/an/an/an/an/an/an/an/a



Kitasato University

Curated by ChEMBL


Assay Description
Displacement of [3H]DPDPE from delta opioid receptor in mouse whole brain devoid of cerebellum


Bioorg Med Chem 21: 3032-50 (2013)

More data for this
Ligand-Target Pair
Delta-type opioid receptor


(MOUSE)
BDBM50102826
PNG
(CHEMBL3339374)
Show SMILES Oc1ccc2CC3N(CC4CC4)CCC45C(Oc1c24)[C@@]1(O)CC[C@@]35N[C@@H]1CC(=O)NCc1ccccc1
Show InChI InChI=1S/C30H35N3O4/c34-21-9-8-20-14-23-30-11-10-29(36,22(32-30)15-24(35)31-16-18-4-2-1-3-5-18)27-28(30,25(20)26(21)37-27)12-13-33(23)17-19-6-7-19/h1-5,8-9,19,22-23,27,32,34,36H,6-7,10-17H2,(H,31,35)/t22-,23?,27?,28?,29-,30-/m1/s1
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0.150n/an/an/an/an/an/an/an/a



Kitasato University

Curated by ChEMBL


Assay Description
Displacement of [3H]DPDPE from delta opioid receptor in mouse brain membranes without cerebellum


Bioorg Med Chem Lett 24: 4980-3 (2014)


Article DOI: 10.1016/j.bmcl.2014.09.029
BindingDB Entry DOI: 10.7270/Q2154JTJ
More data for this
Ligand-Target Pair
Delta-type opioid receptor


(MOUSE)
BDBM21864
PNG
((21R)-22-(cyclopropylmethyl)-14-oxa-11,22-diazahep...)
Show SMILES Oc1ccc2C[C@H]3N(CC4CC4)CCC45C(Oc1c24)c1[nH]c2ccccc2c1CC35O
Show InChI InChI=1S/C26H26N2O3/c29-19-8-7-15-11-20-26(30)12-17-16-3-1-2-4-18(16)27-22(17)24-25(26,21(15)23(19)31-24)9-10-28(20)13-14-5-6-14/h1-4,7-8,14,20,24,27,29-30H,5-6,9-13H2/t20-,24?,25?,26?/m0/s1
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0.150n/an/an/an/an/an/an/an/a



University of Missouri-Columbia

Curated by ChEMBL


Assay Description
Displacement of [3H]NTI from delta opioid receptor in CD1 mouse brain membranes


J Med Chem 50: 2144-56 (2007)


Article DOI: 10.1021/jm0700013
BindingDB Entry DOI: 10.7270/Q2HQ40RW
More data for this
Ligand-Target Pair
Delta-type opioid receptor


(MOUSE)
BDBM50391603
PNG
(CHEMBL2147916)
Show SMILES COc1cccc2nc3C[C@]45CCN(C)[C@H](Cc6ccc(O)cc46)[C@]5(O)Cc3cc12
Show InChI InChI=1S/C25H26N2O3/c1-27-9-8-24-14-21-16(10-18-20(26-21)4-3-5-22(18)30-2)13-25(24,29)23(27)11-15-6-7-17(28)12-19(15)24/h3-7,10,12,23,28-29H,8-9,11,13-14H2,1-2H3/t23-,24-,25-/m1/s1
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0.151n/an/an/an/an/an/an/an/a



Kitasato University

Curated by ChEMBL


Assay Description
Displacement of [3H]DPDPE from delta opioid receptor in mouse whole brain without cerebellum


Bioorg Med Chem 20: 5810-31 (2012)


Article DOI: 10.1016/j.bmc.2012.08.004
BindingDB Entry DOI: 10.7270/Q2F190T5
More data for this
Ligand-Target Pair
Opioid receptors; mu and delta


(MOUSE)
BDBM50491879
PNG
(CHEMBL2387727)
Show SMILES Cl.CN1[C@@H](CC(=O)NCc2ccccc2)[C@]2(O)CC[C@]11[C@H]3Cc4ccc(O)c5O[C@@H]2[C@@]1(CCN3CC1CC1)c45
Show InChI InChI=1S/C31H37N3O4.ClH/c1-33-23(16-25(36)32-17-19-5-3-2-4-6-19)30(37)11-12-31(33)24-15-21-9-10-22(35)27-26(21)29(31,28(30)38-27)13-14-34(24)18-20-7-8-20;/h2-6,9-10,20,23-24,28,35,37H,7-8,11-18H2,1H3,(H,32,36);1H/t23-,24+,28+,29+,30+,31+;/m0./s1
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0.160n/an/an/an/an/an/an/an/a



Kitasato University

Curated by ChEMBL


Assay Description
Displacement of [3H]DPDPE from delta opioid receptor in mouse whole brain devoid of cerebellum


Bioorg Med Chem 21: 3032-50 (2013)

More data for this
Ligand-Target Pair
Opioid receptors; mu and delta


(MOUSE)
BDBM50491897
PNG
(CHEMBL2387739)
Show SMILES Cl.CC(=O)N1[C@@H](CC(=O)Nc2ccccc2)[C@]2(O)CC[C@]11[C@H]3Cc4ccc(O)c5O[C@@H]2[C@@]1(CCN3CC1CC1)c45
Show InChI InChI=1S/C31H35N3O5.ClH/c1-18(35)34-23(16-25(37)32-21-5-3-2-4-6-21)30(38)11-12-31(34)24-15-20-9-10-22(36)27-26(20)29(31,28(30)39-27)13-14-33(24)17-19-7-8-19;/h2-6,9-10,19,23-24,28,36,38H,7-8,11-17H2,1H3,(H,32,37);1H/t23-,24+,28+,29+,30+,31+;/m0./s1
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0.160n/an/an/an/an/an/an/an/a



Kitasato University

Curated by ChEMBL


Assay Description
Displacement of [3H]DPDPE from delta opioid receptor in mouse whole brain devoid of cerebellum


Bioorg Med Chem 21: 3032-50 (2013)

More data for this
Ligand-Target Pair
Delta-type opioid receptor


(MOUSE)
BDBM50329095
PNG
(CHEMBL1270282)
Show SMILES CN1CC[C@]23Cc4nc5ccccc5cc4C[C@@]2(O)[C@H]1Cc1ccc(O)cc31
Show InChI InChI=1S/C24H24N2O2/c1-26-9-8-23-14-21-17(10-16-4-2-3-5-20(16)25-21)13-24(23,28)22(26)11-15-6-7-18(27)12-19(15)23/h2-7,10,12,22,27-28H,8-9,11,13-14H2,1H3/t22-,23-,24-/m1/s1
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0.160n/an/an/an/an/an/an/an/a



Kitasato University

Curated by ChEMBL


Assay Description
Displacement of [3H]DPDPE from delta opioid receptor in mouse whole brain without cerebellum


Bioorg Med Chem 20: 5810-31 (2012)


Article DOI: 10.1016/j.bmc.2012.08.004
BindingDB Entry DOI: 10.7270/Q2F190T5
More data for this
Ligand-Target Pair
Opioid receptors; mu and delta


(MOUSE)
BDBM50329095
PNG
(CHEMBL1270282)
Show SMILES CN1CC[C@]23Cc4nc5ccccc5cc4C[C@@]2(O)[C@H]1Cc1ccc(O)cc31
Show InChI InChI=1S/C24H24N2O2/c1-26-9-8-23-14-21-17(10-16-4-2-3-5-20(16)25-21)13-24(23,28)22(26)11-15-6-7-18(27)12-19(15)23/h2-7,10,12,22,27-28H,8-9,11,13-14H2,1H3/t22-,23-,24-/m1/s1
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0.160n/an/an/an/an/an/an/an/a



Kitasato University

Curated by ChEMBL


Assay Description
Displacement of [3H]-DPDPE from delta opioid receptor in mouse whole brain membranes without cerebellum after 1 hr by liquid scintillation counting a...


Bioorg Med Chem 21: 7628-47 (2013)

More data for this
Ligand-Target Pair
Delta-type opioid receptor


(MOUSE)
BDBM50329095
PNG
(CHEMBL1270282)
Show SMILES CN1CC[C@]23Cc4nc5ccccc5cc4C[C@@]2(O)[C@H]1Cc1ccc(O)cc31
Show InChI InChI=1S/C24H24N2O2/c1-26-9-8-23-14-21-17(10-16-4-2-3-5-20(16)25-21)13-24(23,28)22(26)11-15-6-7-18(27)12-19(15)23/h2-7,10,12,22,27-28H,8-9,11,13-14H2,1H3/t22-,23-,24-/m1/s1
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0.160n/an/an/an/an/an/an/an/a



Kitasato University

Curated by ChEMBL


Assay Description
Displacement of [3H]DPDPE from delta opioid receptor in mouse whole brain membranes


Bioorg Med Chem Lett 20: 6302-5 (2010)


Article DOI: 10.1016/j.bmcl.2010.08.083
BindingDB Entry DOI: 10.7270/Q2G73DZ1
More data for this
Ligand-Target Pair
Opioid receptors; mu and delta


(MOUSE)
BDBM50494882
PNG
(CHEMBL4296730)
Show SMILES Cl.Cl.CCCN1CC[C@]23Cc4nc5ccccc5cc4C[C@@]2(O)[C@H]1Cc1ccc(O)cc31
Show InChI InChI=1S/C26H28N2O2.2ClH/c1-2-10-28-11-9-25-16-23-19(12-18-5-3-4-6-22(18)27-23)15-26(25,30)24(28)13-17-7-8-20(29)14-21(17)25;;/h3-8,12,14,24,29-30H,2,9-11,13,15-16H2,1H3;2*1H/t24-,25-,26-;;/m1../s1
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0.162n/an/an/an/an/an/an/an/a



Kitasato University

Curated by ChEMBL


Assay Description
Displacement of [3H]-DPDPE from delta opioid receptor in mouse whole brain membranes without cerebellum after 1 hr by liquid scintillation counting a...


Bioorg Med Chem 21: 7628-47 (2013)

More data for this
Ligand-Target Pair
Delta-type opioid receptor


(MOUSE)
BDBM21864
PNG
((21R)-22-(cyclopropylmethyl)-14-oxa-11,22-diazahep...)
Show SMILES Oc1ccc2C[C@H]3N(CC4CC4)CCC45C(Oc1c24)c1[nH]c2ccccc2c1CC35O
Show InChI InChI=1S/C26H26N2O3/c29-19-8-7-15-11-20-26(30)12-17-16-3-1-2-4-18(16)27-22(17)24-25(26,21(15)23(19)31-24)9-10-28(20)13-14-5-6-14/h1-4,7-8,14,20,24,27,29-30H,5-6,9-13H2/t20-,24?,25?,26?/m0/s1
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0.170n/an/an/an/an/an/an/an/a



Kitasato University

Curated by ChEMBL


Assay Description
Displacement of [3H]DPDPE from delta opioid receptor in mouse whole brain without cerebellum


Bioorg Med Chem 20: 5810-31 (2012)


Article DOI: 10.1016/j.bmc.2012.08.004
BindingDB Entry DOI: 10.7270/Q2F190T5
More data for this
Ligand-Target Pair
Delta-type opioid receptor


(MOUSE)
BDBM50118177
PNG
(CHEMBL3613171)
Show SMILES Cl.CN([C@@H]1C[C@@]23CCN(CC4CC4)[C@H]4CC[C@@H]1C[C@@]24Cc1ccc(O)cc31)C(=O)\C=C\c1ccoc1
Show InChI InChI=1S/C30H36N2O3.ClH/c1-31(28(34)9-4-21-10-13-35-19-21)26-17-29-11-12-32(18-20-2-3-20)27-8-6-23(26)16-30(27,29)15-22-5-7-24(33)14-25(22)29;/h4-5,7,9-10,13-14,19-20,23,26-27,33H,2-3,6,8,11-12,15-18H2,1H3;1H/b9-4+;/t23-,26-,27+,29-,30-;/m1./s1
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0.182n/an/an/an/an/an/an/an/a



University of Tsukuba

Curated by ChEMBL


Assay Description
Displacement of [3H]DPDPE from DOR in mouse whole brain membranes without cerebellum


Bioorg Med Chem 23: 6271-9 (2015)


Article DOI: 10.1016/j.bmc.2015.08.036
BindingDB Entry DOI: 10.7270/Q2V126M1
More data for this
Ligand-Target Pair
Delta-type opioid receptor


(MOUSE)
BDBM21864
PNG
((21R)-22-(cyclopropylmethyl)-14-oxa-11,22-diazahep...)
Show SMILES Oc1ccc2C[C@H]3N(CC4CC4)CCC45C(Oc1c24)c1[nH]c2ccccc2c1CC35O
Show InChI InChI=1S/C26H26N2O3/c29-19-8-7-15-11-20-26(30)12-17-16-3-1-2-4-18(16)27-22(17)24-25(26,21(15)23(19)31-24)9-10-28(20)13-14-5-6-14/h1-4,7-8,14,20,24,27,29-30H,5-6,9-13H2/t20-,24?,25?,26?/m0/s1
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0.190n/an/an/an/an/an/an/an/a



University of Minnesota

Curated by ChEMBL


Assay Description
Displacement of [3H]- diprenorphine from delta receptor expressed in HEK 293 cells


J Med Chem 44: 857-62 (2001)


Article DOI: 10.1021/jm000381r
BindingDB Entry DOI: 10.7270/Q27H1K9D
More data for this
Ligand-Target Pair
Delta-type opioid receptor


(MOUSE)
BDBM50209644
PNG
(17-cyclopropylmethyl)-6,7-didehydro-4,5alpha-epoxy...)
Show SMILES OC(=O)CN1CCN(CCCCCn2c3[C@H]4Oc5c6c(C[C@H]7N(CC8CC8)CC[C@@]46[C@@]7(O)Cc3c3ccccc23)ccc5O)CCN(CC(O)=O)CCN(CC(O)=O)CC1
Show InChI InChI=1S/C45H60N6O9/c52-35-11-10-31-24-36-45(59)25-33-32-6-2-3-7-34(32)51(41(33)43-44(45,40(31)42(35)60-43)12-15-50(36)26-30-8-9-30)14-5-1-4-13-46-16-18-47(27-37(53)54)20-22-49(29-39(57)58)23-21-48(19-17-46)28-38(55)56/h2-3,6-7,10-11,30,36,43,52,59H,1,4-5,8-9,12-29H2,(H,53,54)(H,55,56)(H,57,58)/t36-,43-,44+,45-/m1/s1
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0.200n/an/an/an/an/an/an/an/a



University of Missouri-Columbia

Curated by ChEMBL


Assay Description
Displacement of [3H]NTI from delta opioid receptor in CD1 mouse brain membranes


J Med Chem 50: 2144-56 (2007)


Article DOI: 10.1021/jm0700013
BindingDB Entry DOI: 10.7270/Q2HQ40RW
More data for this
Ligand-Target Pair
Opioid receptors; mu and delta


(MOUSE)
BDBM50493712
PNG
(CHEMBL2436046)
Show SMILES CCN(CC)C(=O)c1ccc(cc1)C(N1C2CCC1C1CCC2N1CC=C)c1cccc(OC)c1
Show InChI InChI=1S/C30H39N3O2/c1-5-19-32-25-15-16-26(32)28-18-17-27(25)33(28)29(23-9-8-10-24(20-23)35-4)21-11-13-22(14-12-21)30(34)31(6-2)7-3/h5,8-14,20,25-29H,1,6-7,15-19H2,2-4H3
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0.203n/an/an/an/an/an/an/an/a



C.N.R. Istituto di Farmacologia Traslazionale

Curated by ChEMBL


Assay Description
Displacement of [3H]DPDPE from mouse brain delta opioid receptor by scintillation counting analysis


Eur J Med Chem 69: 413-26 (2013)

More data for this
Ligand-Target Pair
Opioid receptors; mu and delta


(MOUSE)
BDBM50494879
PNG
(CHEMBL4296729)
Show SMILES Cl.Cl.Oc1ccc2C[C@H]3N(CC4(O)CC4)CC[C@@]4(Cc5nc6ccccc6cc5C[C@@]34O)c2c1
Show InChI InChI=1S/C27H28N2O3.2ClH/c30-20-6-5-17-12-24-27(32)14-19-11-18-3-1-2-4-22(18)28-23(19)15-26(27,21(17)13-20)9-10-29(24)16-25(31)7-8-25;;/h1-6,11,13,24,30-32H,7-10,12,14-16H2;2*1H/t24-,26-,27-;;/m1../s1
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0.208n/an/an/an/an/an/an/an/a



Kitasato University

Curated by ChEMBL


Assay Description
Displacement of [3H]-DPDPE from delta opioid receptor in mouse whole brain membranes without cerebellum after 1 hr by liquid scintillation counting a...


Bioorg Med Chem 21: 7628-47 (2013)

More data for this
Ligand-Target Pair
Opioid receptors; mu and delta


(MOUSE)
BDBM50494890
PNG
(CHEMBL4296726)
Show SMILES Cl.Cl.Oc1ccc2C[C@H]3N(Cc4ccco4)CC[C@@]4(Cc5nc6ccccc6cc5C[C@@]34O)c2c1
Show InChI InChI=1S/C28H26N2O3.2ClH/c31-21-8-7-18-13-26-28(32)15-20-12-19-4-1-2-6-24(19)29-25(20)16-27(28,23(18)14-21)9-10-30(26)17-22-5-3-11-33-22;;/h1-8,11-12,14,26,31-32H,9-10,13,15-17H2;2*1H/t26-,27-,28-;;/m1../s1
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0.208n/an/an/an/an/an/an/an/a



Kitasato University

Curated by ChEMBL


Assay Description
Displacement of [3H]-DPDPE from delta opioid receptor in mouse whole brain membranes without cerebellum after 1 hr by liquid scintillation counting a...


Bioorg Med Chem 21: 7628-47 (2013)

More data for this
Ligand-Target Pair
Opioid receptors; mu and delta


(MOUSE)
BDBM50493715
PNG
(CHEMBL2436052)
Show SMILES Oc1cccc(c1)C(N1C2CCC1C1CCC2N1CC=C)c1ccc(cc1)C(=O)N1CCCC1
Show InChI InChI=1S/C29H35N3O2/c1-2-16-31-24-12-13-25(31)27-15-14-26(24)32(27)28(22-6-5-7-23(33)19-22)20-8-10-21(11-9-20)29(34)30-17-3-4-18-30/h2,5-11,19,24-28,33H,1,3-4,12-18H2
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0.208n/an/an/an/an/an/an/an/a



C.N.R. Istituto di Farmacologia Traslazionale

Curated by ChEMBL


Assay Description
Displacement of [3H]DPDPE from mouse brain delta opioid receptor by scintillation counting analysis


Eur J Med Chem 69: 413-26 (2013)

More data for this
Ligand-Target Pair
Delta-type opioid receptor


(MOUSE)
BDBM50329098
PNG
(CHEMBL1270383)
Show SMILES Oc1ccc2C[C@H]3N(CC4CCC4)CC[C@@]4(Cc5nc6ccccc6cc5C[C@@]34O)c2c1
Show InChI InChI=1S/C28H30N2O2/c31-22-9-8-19-13-26-28(32)15-21-12-20-6-1-2-7-24(20)29-25(21)16-27(28,23(19)14-22)10-11-30(26)17-18-4-3-5-18/h1-2,6-9,12,14,18,26,31-32H,3-5,10-11,13,15-17H2/t26-,27-,28-/m1/s1
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0.210n/an/an/an/an/an/an/an/a



Kitasato University

Curated by ChEMBL


Assay Description
Displacement of [3H]DPDPE from delta opioid receptor in mouse whole brain membranes


Bioorg Med Chem Lett 20: 6302-5 (2010)


Article DOI: 10.1016/j.bmcl.2010.08.083
BindingDB Entry DOI: 10.7270/Q2G73DZ1
More data for this
Ligand-Target Pair
Opioid receptors; mu and delta


(MOUSE)
BDBM50494887
PNG
(CHEMBL4296731)
Show SMILES Cl.Cl.Oc1ccc2C[C@H]3N(CCF)CC[C@@]4(Cc5nc6ccccc6cc5C[C@@]34O)c2c1
Show InChI InChI=1S/C25H25FN2O2.2ClH/c26-8-10-28-9-7-24-15-22-18(11-17-3-1-2-4-21(17)27-22)14-25(24,30)23(28)12-16-5-6-19(29)13-20(16)24;;/h1-6,11,13,23,29-30H,7-10,12,14-15H2;2*1H/t23-,24-,25-;;/m1../s1
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0.213n/an/an/an/an/an/an/an/a



Kitasato University

Curated by ChEMBL


Assay Description
Displacement of [3H]-DPDPE from delta opioid receptor in mouse whole brain membranes without cerebellum after 1 hr by liquid scintillation counting a...


Bioorg Med Chem 21: 7628-47 (2013)

More data for this
Ligand-Target Pair
Delta-type opioid receptor


(MOUSE)
BDBM50391582
PNG
(CHEMBL2147927)
Show SMILES CN1CC[C@]23Cc4nc5c(cccc5cc4C[C@@]2(O)[C@H]1Cc1ccc(O)cc31)[N+]([O-])=O
Show InChI InChI=1S/C24H23N3O4/c1-26-8-7-23-13-19-16(9-15-3-2-4-20(27(30)31)22(15)25-19)12-24(23,29)21(26)10-14-5-6-17(28)11-18(14)23/h2-6,9,11,21,28-29H,7-8,10,12-13H2,1H3/t21-,23-,24-/m1/s1
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0.218n/an/an/an/an/an/an/an/a



Kitasato University

Curated by ChEMBL


Assay Description
Displacement of [3H]DPDPE from delta opioid receptor in mouse whole brain without cerebellum


Bioorg Med Chem 20: 5810-31 (2012)


Article DOI: 10.1016/j.bmc.2012.08.004
BindingDB Entry DOI: 10.7270/Q2F190T5
More data for this
Ligand-Target Pair
Opioid receptors; mu and delta


(MOUSE)
BDBM50491883
PNG
(CHEMBL3216579)
Show SMILES Cl.Cl.Oc1ccc2C[C@H]3N(CC4CC4)CC[C@]45[C@@H](Oc1c24)[C@@]1(O)CC[C@@]35N[C@H]1CC(=O)Nc1ccccc1
Show InChI InChI=1S/C29H33N3O4.2ClH/c33-20-9-8-18-14-22-29-11-10-28(35,21(31-29)15-23(34)30-19-4-2-1-3-5-19)26-27(29,24(18)25(20)36-26)12-13-32(22)16-17-6-7-17;;/h1-5,8-9,17,21-22,26,31,33,35H,6-7,10-16H2,(H,30,34);2*1H/t21-,22+,26+,27+,28+,29+;;/m0../s1
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0.220n/an/an/an/an/an/an/an/a



Kitasato University

Curated by ChEMBL


Assay Description
Displacement of [3H]DPDPE from delta opioid receptor in mouse whole brain devoid of cerebellum


Bioorg Med Chem 21: 3032-50 (2013)

More data for this
Ligand-Target Pair
Delta-type opioid receptor


(MOUSE)
BDBM50370067
PNG
(CHEMBL1237164)
Show SMILES Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)c1[nH]c2ccccc2c1C[C@@]35O
Show InChI InChI=1S/C26H26N2O3/c29-19-8-7-15-11-20-26(30)12-17-16-3-1-2-4-18(16)27-22(17)24-25(26,21(15)23(19)31-24)9-10-28(20)13-14-5-6-14/h1-4,7-8,14,20,24,27,29-30H,5-6,9-13H2/t20-,24+,25+,26-/m1/s1
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0.220n/an/an/an/an/an/an/an/a



National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL


Assay Description
Displacement of [3H]DADLE at delta-opioid receptor


J Med Chem 44: 1471-4 (2001)


Article DOI: 10.1021/jm000511w
BindingDB Entry DOI: 10.7270/Q2PK0GVP
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Opioid receptors; mu and delta


(MOUSE)
BDBM50494880
PNG
(CHEMBL4296736)
Show SMILES Cl.Cl.CCOCCN1CC[C@]23Cc4nc5ccccc5cc4C[C@@]2(O)[C@H]1Cc1ccc(O)cc31
Show InChI InChI=1S/C27H30N2O3.2ClH/c1-2-32-12-11-29-10-9-26-17-24-20(13-19-5-3-4-6-23(19)28-24)16-27(26,31)25(29)14-18-7-8-21(30)15-22(18)26;;/h3-8,13,15,25,30-31H,2,9-12,14,16-17H2,1H3;2*1H/t25-,26-,27-;;/m1../s1
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0.224n/an/an/an/an/an/an/an/a



Kitasato University

Curated by ChEMBL


Assay Description
Displacement of [3H]-DPDPE from delta opioid receptor in mouse whole brain membranes without cerebellum after 1 hr by liquid scintillation counting a...


Bioorg Med Chem 21: 7628-47 (2013)

More data for this
Ligand-Target Pair
Opioid receptors; mu and delta


(MOUSE)
BDBM50494881
PNG
(CHEMBL4296739)
Show SMILES Cl.Cl.C[C@@H](O)CN1CC[C@]23Cc4nc5ccccc5cc4C[C@@]2(O)[C@H]1Cc1ccc(O)cc31
Show InChI InChI=1S/C26H28N2O3.2ClH/c1-16(29)15-28-9-8-25-14-23-19(10-18-4-2-3-5-22(18)27-23)13-26(25,31)24(28)11-17-6-7-20(30)12-21(17)25;;/h2-7,10,12,16,24,29-31H,8-9,11,13-15H2,1H3;2*1H/t16-,24-,25-,26-;;/m1../s1
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0.225n/an/an/an/an/an/an/an/a



Kitasato University

Curated by ChEMBL


Assay Description
Displacement of [3H]-DPDPE from delta opioid receptor in mouse whole brain membranes without cerebellum after 1 hr by liquid scintillation counting a...


Bioorg Med Chem 21: 7628-47 (2013)

More data for this
Ligand-Target Pair
Opioid receptors; mu and delta


(MOUSE)
BDBM50493711
PNG
(CHEMBL2436050)
Show SMILES CCN(CC)C(=O)c1ccc(cc1)C(N1C2CCC1C1CCC2N1CC=C)c1cccc(O)c1
Show InChI InChI=1S/C29H37N3O2/c1-4-18-31-24-14-15-25(31)27-17-16-26(24)32(27)28(22-8-7-9-23(33)19-22)20-10-12-21(13-11-20)29(34)30(5-2)6-3/h4,7-13,19,24-28,33H,1,5-6,14-18H2,2-3H3
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0.230n/an/an/an/an/an/an/an/a



C.N.R. Istituto di Farmacologia Traslazionale

Curated by ChEMBL


Assay Description
Displacement of [3H]DPDPE from mouse brain delta opioid receptor by scintillation counting analysis


Eur J Med Chem 69: 413-26 (2013)

More data for this
Ligand-Target Pair
Delta-type opioid receptor


(MOUSE)
BDBM50290872
PNG
((-)-rel-3-((4aR,12aS)-2-methyl-1,2,3,4,4a,5,12,12a...)
Show SMILES CN1CC[C@@]2(Cc3nc4ccccc4cc3C[C@H]2C1)c1cccc(O)c1
Show InChI InChI=1S/C23H24N2O/c1-25-10-9-23(18-6-4-7-20(26)13-18)14-22-17(12-19(23)15-25)11-16-5-2-3-8-21(16)24-22/h2-8,11,13,19,26H,9-10,12,14-15H2,1H3/t19-,23+/m0/s1
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0.230n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
inhibition of [3H]DADLE binding to delta-opioid receptor of mouse brain homogenates


Bioorg Med Chem Lett 7: 2967-2972 (1997)


Article DOI: 10.1016/S0960-894X(97)10119-6
BindingDB Entry DOI: 10.7270/Q26110VD
More data for this
Ligand-Target Pair
Delta-type opioid receptor


(MOUSE)
BDBM50391590
PNG
(CHEMBL2147903)
Show SMILES CN1CC[C@]23Cc4nc5c(Cl)cccc5cc4C[C@@]2(O)[C@H]1Cc1ccc(O)cc31
Show InChI InChI=1S/C24H23ClN2O2/c1-27-8-7-23-13-20-16(9-15-3-2-4-19(25)22(15)26-20)12-24(23,29)21(27)10-14-5-6-17(28)11-18(14)23/h2-6,9,11,21,28-29H,7-8,10,12-13H2,1H3/t21-,23-,24-/m1/s1
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0.235n/an/an/an/an/an/an/an/a



Kitasato University

Curated by ChEMBL


Assay Description
Displacement of [3H]DPDPE from delta opioid receptor in mouse whole brain without cerebellum


Bioorg Med Chem 20: 5810-31 (2012)


Article DOI: 10.1016/j.bmc.2012.08.004
BindingDB Entry DOI: 10.7270/Q2F190T5
More data for this
Ligand-Target Pair
Delta-type opioid receptor


(MOUSE)
BDBM50346951
PNG
(CHEMBL1795711 | CHEMBL1795714)
Show SMILES Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)[C@@H](CC[C@@]35O)NC(=O)c1cccc(I)c1
Show InChI InChI=1S/C27H29IN2O4/c28-18-3-1-2-17(12-18)25(32)29-19-8-9-27(33)21-13-16-6-7-20(31)23-22(16)26(27,24(19)34-23)10-11-30(21)14-15-4-5-15/h1-3,6-7,12,15,19,21,24,31,33H,4-5,8-11,13-14H2,(H,29,32)/t19-,21-,24+,26+,27-/m1/s1
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0.240n/an/an/an/an/an/an/an/a



Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL


Assay Description
Displacement of [125I]-BNtxA from mouse cloned DOR-1 expressed in CHO cell membrane after 90 mins


J Med Chem 55: 6352-62 (2012)


Article DOI: 10.1021/jm300305c
BindingDB Entry DOI: 10.7270/Q2930V8C
More data for this
Ligand-Target Pair
Delta-type opioid receptor


(MOUSE)
BDBM50391607
PNG
(CHEMBL2147920)
Show SMILES CN1CC[C@]23Cc4nc5cccc(c5cc4C[C@@]2(O)[C@H]1Cc1ccc(O)cc31)C(F)(F)F
Show InChI InChI=1S/C25H23F3N2O2/c1-30-8-7-23-13-21-15(9-17-18(25(26,27)28)3-2-4-20(17)29-21)12-24(23,32)22(30)10-14-5-6-16(31)11-19(14)23/h2-6,9,11,22,31-32H,7-8,10,12-13H2,1H3/t22-,23-,24-/m1/s1
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0.244n/an/an/an/an/an/an/an/a



Kitasato University

Curated by ChEMBL


Assay Description
Displacement of [3H]DPDPE from delta opioid receptor in mouse whole brain without cerebellum


Bioorg Med Chem 20: 5810-31 (2012)


Article DOI: 10.1016/j.bmc.2012.08.004
BindingDB Entry DOI: 10.7270/Q2F190T5
More data for this
Ligand-Target Pair
Opioid receptors; mu and delta


(MOUSE)
BDBM50494891
PNG
(CHEMBL4296722)
Show SMILES Cl.Cl.COCCN1CC[C@]23Cc4nc5ccccc5cc4C[C@@]2(O)[C@H]1Cc1ccc(O)cc31
Show InChI InChI=1S/C26H28N2O3.2ClH/c1-31-11-10-28-9-8-25-16-23-19(12-18-4-2-3-5-22(18)27-23)15-26(25,30)24(28)13-17-6-7-20(29)14-21(17)25;;/h2-7,12,14,24,29-30H,8-11,13,15-16H2,1H3;2*1H/t24-,25-,26-;;/m1../s1
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0.244n/an/an/an/an/an/an/an/a



Kitasato University

Curated by ChEMBL


Assay Description
Displacement of [3H]-DPDPE from delta opioid receptor in mouse whole brain membranes without cerebellum after 1 hr by liquid scintillation counting a...


Bioorg Med Chem 21: 7628-47 (2013)

More data for this
Ligand-Target Pair
Delta-type opioid receptor


(MOUSE)
BDBM50391593
PNG
(CHEMBL2147906)
Show SMILES CN1CC[C@]23Cc4nc5cc(F)ccc5cc4C[C@@]2(O)[C@H]1Cc1ccc(O)cc31
Show InChI InChI=1S/C24H23FN2O2/c1-27-7-6-23-13-21-16(8-15-2-4-17(25)10-20(15)26-21)12-24(23,29)22(27)9-14-3-5-18(28)11-19(14)23/h2-5,8,10-11,22,28-29H,6-7,9,12-13H2,1H3/t22-,23-,24-/m1/s1
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0.255n/an/an/an/an/an/an/an/a



Kitasato University

Curated by ChEMBL


Assay Description
Displacement of [3H]DPDPE from delta opioid receptor in mouse whole brain without cerebellum


Bioorg Med Chem 20: 5810-31 (2012)


Article DOI: 10.1016/j.bmc.2012.08.004
BindingDB Entry DOI: 10.7270/Q2F190T5
More data for this
Ligand-Target Pair
Opioid receptors; mu and delta


(MOUSE)
BDBM50494884
PNG
(CHEMBL4296737)
Show SMILES Cl.Cl.Oc1ccc2C[C@H]3N(C[C@@H]4CCCO4)CC[C@@]4(Cc5nc6ccccc6cc5C[C@@]34O)c2c1
Show InChI InChI=1S/C28H30N2O3.2ClH/c31-21-8-7-18-13-26-28(32)15-20-12-19-4-1-2-6-24(19)29-25(20)16-27(28,23(18)14-21)9-10-30(26)17-22-5-3-11-33-22;;/h1-2,4,6-8,12,14,22,26,31-32H,3,5,9-11,13,15-17H2;2*1H/t22-,26+,27+,28+;;/m0../s1
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0.257n/an/an/an/an/an/an/an/a



Kitasato University

Curated by ChEMBL


Assay Description
Displacement of [3H]-DPDPE from delta opioid receptor in mouse whole brain membranes without cerebellum after 1 hr by liquid scintillation counting a...


Bioorg Med Chem 21: 7628-47 (2013)

More data for this
Ligand-Target Pair
Delta-type opioid receptor


(MOUSE)
BDBM50391598
PNG
(CHEMBL2147911)
Show SMILES CN1CC[C@]23Cc4nc5c(C)cccc5cc4C[C@@]2(O)[C@H]1Cc1ccc(O)cc31
Show InChI InChI=1S/C25H26N2O2/c1-15-4-3-5-17-10-18-13-25(29)22-11-16-6-7-19(28)12-20(16)24(25,8-9-27(22)2)14-21(18)26-23(15)17/h3-7,10,12,22,28-29H,8-9,11,13-14H2,1-2H3/t22-,24-,25-/m1/s1
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0.267n/an/an/an/an/an/an/an/a



Kitasato University

Curated by ChEMBL


Assay Description
Displacement of [3H]DPDPE from delta opioid receptor in mouse whole brain without cerebellum


Bioorg Med Chem 20: 5810-31 (2012)


Article DOI: 10.1016/j.bmc.2012.08.004
BindingDB Entry DOI: 10.7270/Q2F190T5
More data for this
Ligand-Target Pair
Opioid receptors; mu and delta


(MOUSE)
BDBM50493714
PNG
(CHEMBL2436056)
Show SMILES CCN(CC)C(=O)c1ccc(cc1)C(N1C2CCC3C1CCC2N3CC=C)c1cccc(O)c1
Show InChI InChI=1S/C29H37N3O2/c1-4-18-31-24-14-16-26-25(31)15-17-27(24)32(26)28(22-8-7-9-23(33)19-22)20-10-12-21(13-11-20)29(34)30(5-2)6-3/h4,7-13,19,24-28,33H,1,5-6,14-18H2,2-3H3
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0.267n/an/an/an/an/an/an/an/a



C.N.R. Istituto di Farmacologia Traslazionale

Curated by ChEMBL


Assay Description
Displacement of [3H]DPDPE from mouse brain delta opioid receptor by scintillation counting analysis


Eur J Med Chem 69: 413-26 (2013)

More data for this
Ligand-Target Pair
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