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Compile Data Set for Download or QSAR

Found 4 hits of ki data for polymerid = 50004805   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Arginase-2, mitochondrial


(Homo sapiens (Human))
BDBM50350311
PNG
(CHEMBL1812661)
Show SMILES [NH3+][C@@H](CCCCB(O)O)C([O-])=O
Show InChI InChI=1S/C6H14BNO4/c8-5(6(9)10)3-1-2-4-7(11)12/h5,11-12H,1-4,8H2,(H,9,10)/t5-/m0/s1
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Article
PubMed
8.5n/an/an/an/an/an/an/an/a



Drexel University

Curated by ChEMBL


Assay Description
Binding affinity to human arginase 2


J Med Chem 54: 5432-43 (2011)


Article DOI: 10.1021/jm200443b
BindingDB Entry DOI: 10.7270/Q2TH8N21
More data for this
Ligand-Target Pair
Arginase-2, mitochondrial


(Homo sapiens (Human))
BDBM50008099
PNG
(CHEMBL1234777)
Show SMILES N[C@@H](CCNC(=N)NO)C(O)=O
Show InChI InChI=1S/C5H12N4O3/c6-3(4(10)11)1-2-8-5(7)9-12/h3,12H,1-2,6H2,(H,10,11)(H3,7,8,9)/t3-/m0/s1
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51n/an/an/an/an/an/an/an/a


TBA

Assay Description
Inhibition of arginase 2 (unknown origin)


Citation and Details
More data for this
Ligand-Target Pair
Arginase-2, mitochondrial


(Homo sapiens (Human))
BDBM50462601
PNG
(CHEMBL4250607)
Show SMILES NC(=N)Nc1ccc(cc1)C(F)C(O)=O
Show InChI InChI=1S/C9H10FN3O2/c10-7(8(14)15)5-1-3-6(4-2-5)13-9(11)12/h1-4,7H,(H,14,15)(H4,11,12,13)
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3.22E+5n/an/an/an/an/an/an/an/a



Brown University

Curated by ChEMBL


Assay Description
Irreversible inhibition of human arginase 2 using thioarginine as substrate measured up to 360 mins by UV micro plate method


Bioorg Med Chem 26: 3939-3946 (2018)

More data for this
Ligand-Target Pair
Arginase-2, mitochondrial


(Homo sapiens (Human))
BDBM50462600
PNG
(CHEMBL4238387)
Show SMILES CC(=O)OC(C(O)=O)c1ccc(NC(N)=N)cc1
Show InChI InChI=1S/C11H13N3O4/c1-6(15)18-9(10(16)17)7-2-4-8(5-3-7)14-11(12)13/h2-5,9H,1H3,(H,16,17)(H4,12,13,14)
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4.37E+5n/an/an/an/an/an/an/an/a



Brown University

Curated by ChEMBL


Assay Description
Irreversible inhibition of human arginase 2 using thioarginine as substrate measured up to 360 mins by UV micro plate method


Bioorg Med Chem 26: 3939-3946 (2018)

More data for this
Ligand-Target Pair