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Compile Data Set for Download or QSAR

Found 538 hits Enz. Inhib. hit(s) with Target = 'Capsid protein'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Genome polyprotein


(Human enterovirus 71 (strain BrCr) (Ev 71))
BDBM50457121
PNG
(CHEMBL4210399)
Show SMILES CCO\N=C\c1ccc(OCCC(C)CCN2CCN(C2=O)c2ccnc(N)c2)cc1
Show InChI InChI=1S/C23H31N5O3/c1-3-31-26-17-19-4-6-21(7-5-19)30-15-10-18(2)9-12-27-13-14-28(23(27)29)20-8-11-25-22(24)16-20/h4-8,11,16-18H,3,9-10,12-15H2,1-2H3,(H2,24,25)/b26-17+
PDB

UniProtKB/SwissProt

GoogleScholar
UniChem
PubMed
n/an/an/an/a 0.0300n/an/an/an/a



WuXi AppTec (Shanghai) Co. Ltd

Curated by ChEMBL


Assay Description
Inhibition of Enterovirus 71 Shenzhen/120F1/09 capsid infected in human RD cells assessed as reduction in virus-induced cell death after 72 hrs by CC...


ACS Med Chem Lett 8: 841-846 (2017)

More data for this
Ligand-Target Pair
Human herpes virus 5 capsid protein P40


(Human cytomegalovirus (strain AD169) (HHV-5) (Huma...)
BDBM275769
PNG
(Hexadecyloxypropyl-cyclic cidofovir | US10071110, ...)
Show SMILES CCCCCCCCCCCCCCCCOCCCOP1(=O)COC(Cn2ccc(N)nc2=O)CO1
Show InChI InChI=1/C27H50N3O6P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-19-33-20-16-21-35-37(32)24-34-25(23-36-37)22-30-18-17-26(28)29-27(30)31/h17-18,25H,2-16,19-24H2,1H3,(H2,28,29,31)
PDB
MMDB

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem
Article
US Patent
n/an/an/an/a 0.5n/an/an/an/a



The Regents of the University of California

US Patent


Assay Description
Antiviral assays for HCMV DNA were carried out by DNA hybridization as reported by Dankner, W. M., Scholl, D., Stanat, S. C., Martin, M., Souke, R. L...


US Patent US10071110 (2018)


Article DOI: 10.1016/j.bmcl.2005.04.028
BindingDB Entry DOI: 10.7270/Q2NS0WX9
More data for this
Ligand-Target Pair
Genome polyprotein


(Human enterovirus 71 (strain BrCr) (Ev 71))
BDBM50457116
PNG
(CHEMBL4215737)
Show SMILES CCO\N=C\c1ccc(OCCCCCN2CCN(c3ccnc(N)c3)S2(=O)=O)cc1
Show InChI InChI=1S/C21H29N5O4S/c1-2-30-24-17-18-6-8-20(9-7-18)29-15-5-3-4-12-25-13-14-26(31(25,27)28)19-10-11-23-21(22)16-19/h6-11,16-17H,2-5,12-15H2,1H3,(H2,22,23)/b24-17+
PDB

UniProtKB/SwissProt

GoogleScholar
UniChem
PubMed
n/an/an/an/a 0.900n/an/an/an/a



WuXi AppTec (Shanghai) Co. Ltd

Curated by ChEMBL


Assay Description
Inhibition of Enterovirus 71 Shenzhen/120F1/09 capsid infected in human RD cells assessed as reduction in virus-induced cell death after 72 hrs by CC...


ACS Med Chem Lett 8: 841-846 (2017)

More data for this
Ligand-Target Pair
Gag-Pol polyprotein (Capsid Protein)


(Human immunodeficiency virus type 1 group M subtyp...)
BDBM372411
PNG
(Preparation of (S)-1-(fluoromethyl)-4-((1R,3aS,5aR...)
Show SMILES CC(=C)[C@@H]1CC[C@@]2(CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC=C(C6=CC[C@@](CF)(CC6)C(O)=O)C(C)(C)[C@@H]5CC[C@@]34C)[C@@H]12)NCCN1CCC(C)(O)CC1
Show InChI InChI=1/C45H71FN2O3/c1-30(2)32-13-20-45(47-25-28-48-26-23-40(5,51)24-27-48)22-21-42(7)34(37(32)45)9-10-36-41(6)16-14-33(39(3,4)35(41)15-17-43(36,42)8)31-11-18-44(29-46,19-12-31)38(49)50/h11,14,32,34-37,47,51H,1,9-10,12-13,15-29H2,2-8H3,(H,49,50)/t32-,34+,35-,36+,37+,41-,42+,43+,44-,45-/s2
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 1.21n/an/an/an/a



VIIV HEALTHCARE UK (NO. 4) LIMITED

US Patent


Assay Description
MT-2 cells and 293T cells were obtained from the NIH AIDS Research and Reference Reagent Program. MT-2 cells were propagated in RPMI 1640 media suppl...


US Patent US10245275 (2019)

More data for this
Ligand-Target Pair
Gag-Pol polyprotein (Capsid Protein)


(Human immunodeficiency virus type 1 group M subtyp...)
BDBM372344
PNG
(Preparation of diasteromeric (1R)- and (1S)-4-((1R...)
Show SMILES CC(=C)[C@@H]1CC[C@@]2(CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC=C(C6=CCC(CF)(CC6)C(O)=O)C(C)(C)[C@@H]5CC[C@@]34C)[C@@H]12)NCCN1CCS(=O)(=O)CC1
Show InChI InChI=1/C43H67FN2O4S/c1-29(2)31-12-19-43(45-22-23-46-24-26-51(49,50)27-25-46)21-20-40(6)33(36(31)43)8-9-35-39(5)15-13-32(38(3,4)34(39)14-16-41(35,40)7)30-10-17-42(28-44,18-11-30)37(47)48/h10,13,31,33-36,45H,1,8-9,11-12,14-28H2,2-7H3,(H,47,48)/t31-,33+,34-,35+,36+,39-,40+,41+,42?,43-/s2
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 1.29n/an/an/an/a



VIIV HEALTHCARE UK (NO. 4) LIMITED

US Patent


Assay Description
MT-2 cells and 293T cells were obtained from the NIH AIDS Research and Reference Reagent Program. MT-2 cells were propagated in RPMI 1640 media suppl...


US Patent US10245275 (2019)

More data for this
Ligand-Target Pair
Gag-Pol polyprotein (Capsid Protein)


(Human immunodeficiency virus type 1 group M subtyp...)
BDBM372366
PNG
(Preparation of (R)-4-((1S,3aS,5aR,5bR,7aR,11aS,11b...)
Show SMILES CC(C)[C@@H]1CC[C@@]2(CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC=C(C6=CC[C@](CF)(CC6)C(O)=O)C(C)(C)[C@@H]5CC[C@@]34C)[C@@H]12)NCCN1CCS(=O)(=O)CC1
Show InChI InChI=1/C43H69FN2O4S/c1-29(2)31-12-19-43(45-22-23-46-24-26-51(49,50)27-25-46)21-20-40(6)33(36(31)43)8-9-35-39(5)15-13-32(38(3,4)34(39)14-16-41(35,40)7)30-10-17-42(28-44,18-11-30)37(47)48/h10,13,29,31,33-36,45H,8-9,11-12,14-28H2,1-7H3,(H,47,48)/t31-,33+,34-,35+,36+,39-,40+,41+,42+,43-/s2
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 1.34n/an/an/an/a



VIIV HEALTHCARE UK (NO. 4) LIMITED

US Patent


Assay Description
MT-2 cells and 293T cells were obtained from the NIH AIDS Research and Reference Reagent Program. MT-2 cells were propagated in RPMI 1640 media suppl...


US Patent US10245275 (2019)

More data for this
Ligand-Target Pair
Gag-Pol polyprotein (Capsid Protein)


(Human immunodeficiency virus type 1 group M subtyp...)
BDBM372407
PNG
(Preparation of (S)-1-(fluoromethyl)-4-((1R,3aS,5aR...)
Show SMILES CC(=C)[C@@H]1CC[C@@]2(CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC=C(C6=CC[C@@](CF)(CC6)C(O)=O)C(C)(C)[C@@H]5CC[C@@]34C)[C@@H]12)NCC[C@@]1(O)CC[C@@H](CC1)S(C)(=O)=O
Show InChI InChI=1/C46H72FNO5S/c1-30(2)33-15-24-46(48-28-27-45(51)22-13-32(14-23-45)54(8,52)53)26-25-42(6)35(38(33)46)9-10-37-41(5)18-16-34(40(3,4)36(41)17-19-43(37,42)7)31-11-20-44(29-47,21-12-31)39(49)50/h11,16,32-33,35-38,48,51H,1,9-10,12-15,17-29H2,2-8H3,(H,49,50)/t32-,33-,35+,36-,37+,38+,41-,42+,43+,44-,45+,46-/s2
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 1.35n/an/an/an/a



VIIV HEALTHCARE UK (NO. 4) LIMITED

US Patent


Assay Description
MT-2 cells and 293T cells were obtained from the NIH AIDS Research and Reference Reagent Program. MT-2 cells were propagated in RPMI 1640 media suppl...


US Patent US10245275 (2019)

More data for this
Ligand-Target Pair
Gag-Pol polyprotein (Capsid Protein)


(Human immunodeficiency virus type 1 group M subtyp...)
BDBM372348
PNG
(Preparation of (S)-4-((1R,3aS,5aR,5bR,7aR,11aS,11b...)
Show SMILES CC(=C)[C@@H]1CC[C@@]2(CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC=C(C6=CC[C@@](CF)(CC6)C(O)=O)C(C)(C)[C@@H]5CC[C@@]34C)[C@@H]12)NCCN1C[C@@H]2C[C@@H]1CS2(=O)=O
Show InChI InChI=1/C44H67FN2O4S/c1-28(2)32-12-19-44(46-22-23-47-25-31-24-30(47)26-52(31,50)51)21-20-41(6)34(37(32)44)8-9-36-40(5)15-13-33(39(3,4)35(40)14-16-42(36,41)7)29-10-17-43(27-45,18-11-29)38(48)49/h10,13,30-32,34-37,46H,1,8-9,11-12,14-27H2,2-7H3,(H,48,49)/t30-,31+,32+,34-,35+,36-,37-,40+,41-,42-,43+,44+/s2
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 1.41n/an/an/an/a



VIIV HEALTHCARE UK (NO. 4) LIMITED

US Patent


Assay Description
MT-2 cells and 293T cells were obtained from the NIH AIDS Research and Reference Reagent Program. MT-2 cells were propagated in RPMI 1640 media suppl...


US Patent US10245275 (2019)

More data for this
Ligand-Target Pair
Gag-Pol polyprotein (Capsid Protein)


(Human immunodeficiency virus type 1 group M subtyp...)
BDBM372346
PNG
(Method A: (R)-4-((1R,3aS,5aR,5bR,7aR,11aS,11bR,13a...)
Show SMILES CC(=C)[C@@H]1CC[C@@]2(CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC=C(C6=CC[C@](CF)(CC6)C(O)=O)C(C)(C)[C@@H]5CC[C@@]34C)[C@@H]12)NCCN1CCS(=O)(=O)CC1
Show InChI InChI=1/C43H67FN2O4S/c1-29(2)31-12-19-43(45-22-23-46-24-26-51(49,50)27-25-46)21-20-40(6)33(36(31)43)8-9-35-39(5)15-13-32(38(3,4)34(39)14-16-41(35,40)7)30-10-17-42(28-44,18-11-30)37(47)48/h10,13,31,33-36,45H,1,8-9,11-12,14-28H2,2-7H3,(H,47,48)/t31-,33+,34-,35+,36+,39-,40+,41+,42+,43-/s2
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 1.48n/an/an/an/a



VIIV HEALTHCARE UK (NO. 4) LIMITED

US Patent


Assay Description
MT-2 cells and 293T cells were obtained from the NIH AIDS Research and Reference Reagent Program. MT-2 cells were propagated in RPMI 1640 media suppl...


US Patent US10245275 (2019)

More data for this
Ligand-Target Pair
Gag-Pol polyprotein (Capsid Protein)


(Human immunodeficiency virus type 1 group M subtyp...)
BDBM372380
PNG
(Preparation of (S)-4-((1R,3aS,5aR,5bR,7aR,11aS,11b...)
Show SMILES CC(=C)[C@@H]1CC[C@@]2(CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC=C(C6=CC[C@@](CF)(CC6)C(O)=O)C(C)(C)[C@@H]5CC[C@@]34C)[C@@H]12)NCC(=O)N1CCS(=O)(=O)C1
Show InChI InChI=1/C42H63FN2O5S/c1-27(2)29-12-19-42(44-24-34(46)45-22-23-51(49,50)26-45)21-20-39(6)31(35(29)42)8-9-33-38(5)15-13-30(37(3,4)32(38)14-16-40(33,39)7)28-10-17-41(25-43,18-11-28)36(47)48/h10,13,29,31-33,35,44H,1,8-9,11-12,14-26H2,2-7H3,(H,47,48)/t29-,31+,32-,33+,35+,38-,39+,40+,41-,42-/s2
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 1.57n/an/an/an/a



VIIV HEALTHCARE UK (NO. 4) LIMITED

US Patent


Assay Description
MT-2 cells and 293T cells were obtained from the NIH AIDS Research and Reference Reagent Program. MT-2 cells were propagated in RPMI 1640 media suppl...


US Patent US10245275 (2019)

More data for this
Ligand-Target Pair
Gag-Pol polyprotein (Capsid Protein)


(Human immunodeficiency virus type 1 group M subtyp...)
BDBM372349
PNG
(Preparation of (S)-4-((1R,3aS,5aR,5bR,7aR,11aS,11b...)
Show SMILES CC(=C)[C@@H]1CC[C@@]2(CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC=C(C6=CC[C@@](CF)(CC6)C(O)=O)C(C)(C)[C@@H]5CC[C@@]34C)[C@@H]12)NCCN1CCCS(=O)(=O)CC1
Show InChI InChI=1/C44H69FN2O4S/c1-30(2)32-13-20-44(46-23-25-47-24-8-27-52(50,51)28-26-47)22-21-41(6)34(37(32)44)9-10-36-40(5)16-14-33(39(3,4)35(40)15-17-42(36,41)7)31-11-18-43(29-45,19-12-31)38(48)49/h11,14,32,34-37,46H,1,8-10,12-13,15-29H2,2-7H3,(H,48,49)/t32-,34+,35-,36+,37+,40-,41+,42+,43-,44-/s2
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 1.60n/an/an/an/a



VIIV HEALTHCARE UK (NO. 4) LIMITED

US Patent


Assay Description
MT-2 cells and 293T cells were obtained from the NIH AIDS Research and Reference Reagent Program. MT-2 cells were propagated in RPMI 1640 media suppl...


US Patent US10245275 (2019)

More data for this
Ligand-Target Pair
Gag-Pol polyprotein (Capsid Protein)


(Human immunodeficiency virus type 1 group M subtyp...)
BDBM372406
PNG
(Preparation of (S)-4-((1R,3aS,5aR,5bR,7aR,11aS,11b...)
Show SMILES CC(=C)[C@@H]1CC[C@@]2(CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC=C(C6=CC[C@@](CF)(CC6)C(O)=O)C(C)(C)[C@@H]5CC[C@@]34C)[C@@H]12)NCC[C@]1(O)CC[C@@](C)(O)CC1
Show InChI InChI=1/C46H72FNO4/c1-30(2)32-13-20-46(48-28-27-45(52)24-21-40(5,51)22-25-45)26-23-42(7)34(37(32)46)9-10-36-41(6)16-14-33(39(3,4)35(41)15-17-43(36,42)8)31-11-18-44(29-47,19-12-31)38(49)50/h11,14,32,34-37,48,51-52H,1,9-10,12-13,15-29H2,2-8H3,(H,49,50)/t32-,34+,35-,36+,37+,40-,41-,42+,43+,44-,45+,46-/s2
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 1.65n/an/an/an/a



VIIV HEALTHCARE UK (NO. 4) LIMITED

US Patent


Assay Description
MT-2 cells and 293T cells were obtained from the NIH AIDS Research and Reference Reagent Program. MT-2 cells were propagated in RPMI 1640 media suppl...


US Patent US10245275 (2019)

More data for this
Ligand-Target Pair
Gag-Pol polyprotein (Capsid Protein)


(Human immunodeficiency virus type 1 group M subtyp...)
BDBM372403
PNG
(Preparation of (S)-4-((1R,3aS,5aR,5bR,7aR,11aS,11b...)
Show SMILES CC(=C)[C@@H]1CC[C@@]2(CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC=C(C6=CC[C@@](CF)(CC6)C(O)=O)C(C)(C)[C@@H]5CC[C@@]34C)[C@@H]12)NCCC1(O)CCN(CC1)C(C)=O
Show InChI InChI=1/C46H71FN2O4/c1-30(2)33-13-20-46(48-26-23-45(53)24-27-49(28-25-45)31(3)50)22-21-42(7)35(38(33)46)9-10-37-41(6)16-14-34(40(4,5)36(41)15-17-43(37,42)8)32-11-18-44(29-47,19-12-32)39(51)52/h11,14,33,35-38,48,53H,1,9-10,12-13,15-29H2,2-8H3,(H,51,52)/t33-,35+,36-,37+,38+,41-,42+,43+,44-,46-/s2
PDB
MMDB

UniProtKB/SwissProt

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GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 1.73n/an/an/an/a



VIIV HEALTHCARE UK (NO. 4) LIMITED

US Patent


Assay Description
MT-2 cells and 293T cells were obtained from the NIH AIDS Research and Reference Reagent Program. MT-2 cells were propagated in RPMI 1640 media suppl...


US Patent US10245275 (2019)

More data for this
Ligand-Target Pair
Gag-Pol polyprotein (Capsid Protein)


(Human immunodeficiency virus type 1 group M subtyp...)
BDBM372339
PNG
(Preparation of diastereomeric (1R)- and (1S)-1-(fl...)
Show SMILES CC(=C)[C@@H]1CC[C@@]2(CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC=C(C6=CCC(CF)(CC6)C(O)=O)C(C)(C)[C@@H]5CC[C@@]34C)[C@@H]12)NCCN1CCC(CC1)S(C)(=O)=O
Show InChI InChI=1/C45H71FN2O4S/c1-30(2)33-13-22-45(47-25-28-48-26-16-32(17-27-48)53(8,51)52)24-23-42(6)35(38(33)45)9-10-37-41(5)18-14-34(40(3,4)36(41)15-19-43(37,42)7)31-11-20-44(29-46,21-12-31)39(49)50/h11,14,32-33,35-38,47H,1,9-10,12-13,15-29H2,2-8H3,(H,49,50)/t33-,35+,36-,37+,38+,41-,42+,43+,44?,45-/s2
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
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PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 1.75n/an/an/an/a



VIIV HEALTHCARE UK (NO. 4) LIMITED

US Patent


Assay Description
MT-2 cells and 293T cells were obtained from the NIH AIDS Research and Reference Reagent Program. MT-2 cells were propagated in RPMI 1640 media suppl...


US Patent US10245275 (2019)

More data for this
Ligand-Target Pair
Gag-Pol polyprotein (Capsid Protein)


(Human immunodeficiency virus type 1 group M subtyp...)
BDBM372342
PNG
(Preparation of (R)-1-(fluoromethyl)-4-((1R,3aS,5aR...)
Show SMILES CC(=C)[C@@H]1CC[C@@]2(CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC=C(C6=CC[C@](CF)(CC6)C(O)=O)C(C)(C)[C@@H]5CC[C@@]34C)[C@@H]12)NCCN1CCC(CC1)S(C)(=O)=O
Show InChI InChI=1/C45H71FN2O4S/c1-30(2)33-13-22-45(47-25-28-48-26-16-32(17-27-48)53(8,51)52)24-23-42(6)35(38(33)45)9-10-37-41(5)18-14-34(40(3,4)36(41)15-19-43(37,42)7)31-11-20-44(29-46,21-12-31)39(49)50/h11,14,32-33,35-38,47H,1,9-10,12-13,15-29H2,2-8H3,(H,49,50)/t33-,35+,36-,37+,38+,41-,42+,43+,44+,45-/s2
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
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PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 1.93n/an/an/an/a



VIIV HEALTHCARE UK (NO. 4) LIMITED

US Patent


Assay Description
MT-2 cells and 293T cells were obtained from the NIH AIDS Research and Reference Reagent Program. MT-2 cells were propagated in RPMI 1640 media suppl...


US Patent US10245275 (2019)

More data for this
Ligand-Target Pair
Gag-Pol polyprotein (Capsid Protein)


(Human immunodeficiency virus type 1 group M subtyp...)
BDBM372350
PNG
(Preparation of (S)-1-(fluoromethyl)-4-((1R,3aS,5aR...)
Show SMILES CC(=C)[C@@H]1CC[C@@]2(CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC=C(C6=CC[C@@](CF)(CC6)C(O)=O)C(C)(C)[C@@H]5CC[C@@]34C)[C@@H]12)NCCN1CCN(CC1)S(C)(=O)=O
Show InChI InChI=1/C44H70FN3O4S/c1-30(2)32-13-20-44(46-23-24-47-25-27-48(28-26-47)53(8,51)52)22-21-41(6)34(37(32)44)9-10-36-40(5)16-14-33(39(3,4)35(40)15-17-42(36,41)7)31-11-18-43(29-45,19-12-31)38(49)50/h11,14,32,34-37,46H,1,9-10,12-13,15-29H2,2-8H3,(H,49,50)/t32-,34+,35-,36+,37+,40-,41+,42+,43-,44-/s2
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n/an/an/an/a 1.95n/an/an/an/a



VIIV HEALTHCARE UK (NO. 4) LIMITED

US Patent


Assay Description
MT-2 cells and 293T cells were obtained from the NIH AIDS Research and Reference Reagent Program. MT-2 cells were propagated in RPMI 1640 media suppl...


US Patent US10245275 (2019)

More data for this
Ligand-Target Pair
Gag-Pol polyprotein (Capsid Protein)


(Human immunodeficiency virus type 1 group M subtyp...)
BDBM372345
PNG
(US10245275, Example 2a)
Show SMILES CC(=C)[C@@H]1CC[C@@]2(CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC=C(C6=CC[C@@](CF)(CC6)C(O)=O)C(C)(C)[C@@H]5CC[C@@]34C)[C@@H]12)NCCN1CCS(=O)(=O)CC1
Show InChI InChI=1/C43H67FN2O4S/c1-29(2)31-12-19-43(45-22-23-46-24-26-51(49,50)27-25-46)21-20-40(6)33(36(31)43)8-9-35-39(5)15-13-32(38(3,4)34(39)14-16-41(35,40)7)30-10-17-42(28-44,18-11-30)37(47)48/h10,13,31,33-36,45H,1,8-9,11-12,14-28H2,2-7H3,(H,47,48)/t31-,33+,34-,35+,36+,39-,40+,41+,42-,43-/s2
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n/an/an/an/a 1.98n/an/an/an/a



VIIV HEALTHCARE UK (NO. 4) LIMITED

US Patent


Assay Description
MT-2 cells and 293T cells were obtained from the NIH AIDS Research and Reference Reagent Program. MT-2 cells were propagated in RPMI 1640 media suppl...


US Patent US10245275 (2019)

More data for this
Ligand-Target Pair
Gag-Pol polyprotein (Capsid Protein)


(Human immunodeficiency virus type 1 group M subtyp...)
BDBM372417
PNG
(US10245275, Compound B)
Show SMILES CC(=C)[C@@H]1CC[C@@]2(CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC=C(C6=CCC(C)(CC6)OC=O)C(C)(C)[C@@H]5CC[C@@]34C)[C@@H]12)NCCN1CCS(=O)(=O)CC1
Show InChI InChI=1/C43H68N2O4S/c1-30(2)32-13-20-43(44-23-24-45-25-27-50(47,48)28-26-45)22-21-41(7)34(37(32)43)9-10-36-40(6)18-14-33(31-11-16-39(5,17-12-31)49-29-46)38(3,4)35(40)15-19-42(36,41)8/h11,14,29,32,34-37,44H,1,9-10,12-13,15-28H2,2-8H3/t32-,34+,35-,36+,37+,39?,40-,41+,42+,43-/s2
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n/an/an/an/a 2n/an/an/an/a



VIIV HEALTHCARE UK (NO. 4) LIMITED

US Patent


Assay Description
MT-2 cells and 293T cells were obtained from the NIH AIDS Research and Reference Reagent Program. MT-2 cells were propagated in RPMI 1640 media suppl...


US Patent US10245275 (2019)

More data for this
Ligand-Target Pair
Gag-Pol polyprotein (Capsid Protein)


(Human immunodeficiency virus type 1 group M subtyp...)
BDBM372418
PNG
(US10245275, Compound 2)
Show SMILES CC(=C)[C@@H]1CC[C@@]2(CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC=C(C6=CCC(CF)(CC6)OC=O)C(C)(C)[C@@H]5CC[C@@]34C)[C@@H]12)NCCN1CCS(=O)(=O)CC1
Show InChI InChI=1/C43H67FN2O4S/c1-30(2)32-12-19-43(45-22-23-46-24-26-51(48,49)27-25-46)21-20-40(6)34(37(32)43)8-9-36-39(5)15-13-33(38(3,4)35(39)14-16-41(36,40)7)31-10-17-42(28-44,18-11-31)50-29-47/h10,13,29,32,34-37,45H,1,8-9,11-12,14-28H2,2-7H3/t32-,34+,35-,36+,37+,39-,40+,41+,42?,43-/s2
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n/an/an/an/a 2n/an/an/an/a



VIIV HEALTHCARE UK (NO. 4) LIMITED

US Patent


Assay Description
MT-2 cells and 293T cells were obtained from the NIH AIDS Research and Reference Reagent Program. MT-2 cells were propagated in RPMI 1640 media suppl...


US Patent US10245275 (2019)

More data for this
Ligand-Target Pair
Gag-Pol polyprotein (Capsid Protein)


(Human immunodeficiency virus type 1 group M subtyp...)
BDBM372419
PNG
(US10245275, Compound 2a)
Show SMILES CC(=C)[C@@H]1CC[C@@]2(CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC=C(C6=CC[C@@](CF)(CC6)OC=O)C(C)(C)[C@@H]5CC[C@@]34C)[C@@H]12)NCCN1CCS(=O)(=O)CC1
Show InChI InChI=1/C43H67FN2O4S/c1-30(2)32-12-19-43(45-22-23-46-24-26-51(48,49)27-25-46)21-20-40(6)34(37(32)43)8-9-36-39(5)15-13-33(38(3,4)35(39)14-16-41(36,40)7)31-10-17-42(28-44,18-11-31)50-29-47/h10,13,29,32,34-37,45H,1,8-9,11-12,14-28H2,2-7H3/t32-,34+,35-,36+,37+,39-,40+,41+,42-,43-/s2
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n/an/an/an/a 2n/an/an/an/a



VIIV HEALTHCARE UK (NO. 4) LIMITED

US Patent


Assay Description
MT-2 cells and 293T cells were obtained from the NIH AIDS Research and Reference Reagent Program. MT-2 cells were propagated in RPMI 1640 media suppl...


US Patent US10245275 (2019)

More data for this
Ligand-Target Pair
Gag-Pol polyprotein (Capsid Protein)


(Human immunodeficiency virus type 1 group M subtyp...)
BDBM372400
PNG
(Preparation of (S)-1-(fluoromethyl)-4-((1R,3aS,5aR...)
Show SMILES CC(=C)[C@@H]1CC[C@@]2(CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC=C(C6=CC[C@@](CF)(CC6)C(O)=O)C(C)(C)[C@@H]5CC[C@@]34C)[C@@H]12)NCCC1(O)CCOCC1
Show InChI InChI=1/C44H68FNO4/c1-29(2)31-12-19-44(46-25-22-43(49)23-26-50-27-24-43)21-20-40(6)33(36(31)44)8-9-35-39(5)15-13-32(38(3,4)34(39)14-16-41(35,40)7)30-10-17-42(28-45,18-11-30)37(47)48/h10,13,31,33-36,46,49H,1,8-9,11-12,14-28H2,2-7H3,(H,47,48)/t31-,33+,34-,35+,36+,39-,40+,41+,42-,44-/s2
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n/an/an/an/a 2.01n/an/an/an/a



VIIV HEALTHCARE UK (NO. 4) LIMITED

US Patent


Assay Description
MT-2 cells and 293T cells were obtained from the NIH AIDS Research and Reference Reagent Program. MT-2 cells were propagated in RPMI 1640 media suppl...


US Patent US10245275 (2019)

More data for this
Ligand-Target Pair
Gag-Pol polyprotein (Capsid Protein)


(Human immunodeficiency virus type 1 group M subtyp...)
BDBM372404
PNG
(Preparation of (S)-4-((1R,3aS,5aR,5bR,7aR,11aS,11b...)
Show SMILES CC(=C)[C@@H]1CC[C@@]2(CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC=C(C6=CC[C@@](CF)(CC6)C(O)=O)C(C)(C)[C@@H]5CC[C@@]34C)[C@@H]12)NCC[C@@]1(O)CC[C@@](C)(O)CC1
Show InChI InChI=1/C46H72FNO4/c1-30(2)32-13-20-46(48-28-27-45(52)24-21-40(5,51)22-25-45)26-23-42(7)34(37(32)46)9-10-36-41(6)16-14-33(39(3,4)35(41)15-17-43(36,42)8)31-11-18-44(29-47,19-12-31)38(49)50/h11,14,32,34-37,48,51-52H,1,9-10,12-13,15-29H2,2-8H3,(H,49,50)/t32-,34+,35-,36+,37+,40-,41-,42+,43+,44-,45-,46-/s2
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n/an/an/an/a 2.10n/an/an/an/a



VIIV HEALTHCARE UK (NO. 4) LIMITED

US Patent


Assay Description
MT-2 cells and 293T cells were obtained from the NIH AIDS Research and Reference Reagent Program. MT-2 cells were propagated in RPMI 1640 media suppl...


US Patent US10245275 (2019)

More data for this
Ligand-Target Pair
Gag-Pol polyprotein (Capsid Protein)


(Human immunodeficiency virus type 1 group M subtyp...)
BDBM372341
PNG
(US10245275, Example 1a)
Show SMILES CC(=C)[C@@H]1CC[C@@]2(CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC=C(C6=CC[C@@](CF)(CC6)C(O)=O)C(C)(C)[C@@H]5CC[C@@]34C)[C@@H]12)NCCN1CCC(CC1)S(C)(=O)=O
Show InChI InChI=1/C45H71FN2O4S/c1-30(2)33-13-22-45(47-25-28-48-26-16-32(17-27-48)53(8,51)52)24-23-42(6)35(38(33)45)9-10-37-41(5)18-14-34(40(3,4)36(41)15-19-43(37,42)7)31-11-20-44(29-46,21-12-31)39(49)50/h11,14,32-33,35-38,47H,1,9-10,12-13,15-29H2,2-8H3,(H,49,50)/t33-,35+,36-,37+,38+,41-,42+,43+,44-,45-/s2
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n/an/an/an/a 2.25n/an/an/an/a



VIIV HEALTHCARE UK (NO. 4) LIMITED

US Patent


Assay Description
MT-2 cells and 293T cells were obtained from the NIH AIDS Research and Reference Reagent Program. MT-2 cells were propagated in RPMI 1640 media suppl...


US Patent US10245275 (2019)

More data for this
Ligand-Target Pair
Gag-Pol polyprotein (Capsid Protein)


(Human immunodeficiency virus type 1 group M subtyp...)
BDBM372396
PNG
(Preparation of (1S)-4-((1R,3aS,5aR,5bR,7aR,11aS,11...)
Show SMILES CC(=C)[C@@H]1CC[C@@]2(CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC=C(C6=CC[C@@](CF)(CC6)C(O)=O)C(C)(C)[C@@H]5CC[C@@]34C)[C@@H]12)NCC(O)CN1CCS(=O)(=O)CC1
Show InChI InChI=1/C44H69FN2O5S/c1-29(2)32-12-19-44(46-26-31(48)27-47-22-24-53(51,52)25-23-47)21-20-41(6)34(37(32)44)8-9-36-40(5)15-13-33(39(3,4)35(40)14-16-42(36,41)7)30-10-17-43(28-45,18-11-30)38(49)50/h10,13,31-32,34-37,46,48H,1,8-9,11-12,14-28H2,2-7H3,(H,49,50)/t31?,32-,34+,35-,36+,37+,40-,41+,42+,43-,44-/s2
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n/an/an/an/a 2.33n/an/an/an/a



VIIV HEALTHCARE UK (NO. 4) LIMITED

US Patent


Assay Description
MT-2 cells and 293T cells were obtained from the NIH AIDS Research and Reference Reagent Program. MT-2 cells were propagated in RPMI 1640 media suppl...


US Patent US10245275 (2019)

More data for this
Ligand-Target Pair
Gag-Pol polyprotein (Capsid Protein)


(Human immunodeficiency virus type 1 group M subtyp...)
BDBM372364
PNG
(Preparation of (S)-1-(fluoromethyl)-4-((1R,3aS,5aR...)
Show SMILES CC(=C)[C@@H]1CC[C@@]2(CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC=C(C6=CC[C@@](CF)(CC6)C(O)=O)C(C)(C)[C@@H]5CC[C@@]34C)[C@@H]12)NCCN1CCCC1=O
Show InChI InChI=1/C43H65FN2O3/c1-28(2)30-14-21-43(45-24-26-46-25-8-9-35(46)47)23-22-40(6)32(36(30)43)10-11-34-39(5)17-15-31(38(3,4)33(39)16-18-41(34,40)7)29-12-19-42(27-44,20-13-29)37(48)49/h12,15,30,32-34,36,45H,1,8-11,13-14,16-27H2,2-7H3,(H,48,49)/t30-,32+,33-,34+,36+,39-,40+,41+,42-,43-/s2
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n/an/an/an/a 2.53n/an/an/an/a



VIIV HEALTHCARE UK (NO. 4) LIMITED

US Patent


Assay Description
MT-2 cells and 293T cells were obtained from the NIH AIDS Research and Reference Reagent Program. MT-2 cells were propagated in RPMI 1640 media suppl...


US Patent US10245275 (2019)

More data for this
Ligand-Target Pair
Gag-Pol polyprotein (Capsid Protein)


(Human immunodeficiency virus type 1 group M subtyp...)
BDBM372402
PNG
(Preparation of (S)-1-(fluoromethyl)-4-((1R,3aS,5aR...)
Show SMILES CC(=C)[C@@H]1CC[C@@]2(CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC=C(C6=CC[C@@](CF)(CC6)C(O)=O)C(C)(C)[C@@H]5CC[C@@]34C)[C@@H]12)NCCC1(O)CCN(CC1)S(C)(=O)=O
Show InChI InChI=1/C45H71FN2O5S/c1-30(2)32-13-20-45(47-26-23-44(51)24-27-48(28-25-44)54(8,52)53)22-21-41(6)34(37(32)45)9-10-36-40(5)16-14-33(39(3,4)35(40)15-17-42(36,41)7)31-11-18-43(29-46,19-12-31)38(49)50/h11,14,32,34-37,47,51H,1,9-10,12-13,15-29H2,2-8H3,(H,49,50)/t32-,34+,35-,36+,37+,40-,41+,42+,43-,45-/s2
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n/an/an/an/a 2.56n/an/an/an/a



VIIV HEALTHCARE UK (NO. 4) LIMITED

US Patent


Assay Description
MT-2 cells and 293T cells were obtained from the NIH AIDS Research and Reference Reagent Program. MT-2 cells were propagated in RPMI 1640 media suppl...


US Patent US10245275 (2019)

More data for this
Ligand-Target Pair
Gag-Pol polyprotein (Capsid Protein)


(Human immunodeficiency virus type 1 group M subtyp...)
BDBM372375
PNG
(Preparation of (S)-1-(fluoromethyl)-4-((1R,3aS,5aR...)
Show SMILES CC(=C)[C@@H]1CC[C@@]2(CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC=C(C6=CC[C@@](CF)(CC6)C(O)=O)C(C)(C)[C@@H]5CC[C@@]34C)[C@@H]12)NCC(=O)N1CCC(C)(O)CC1
Show InChI InChI=1/C45H69FN2O4/c1-29(2)31-13-20-45(47-27-36(49)48-25-23-40(5,52)24-26-48)22-21-42(7)33(37(31)45)9-10-35-41(6)16-14-32(39(3,4)34(41)15-17-43(35,42)8)30-11-18-44(28-46,19-12-30)38(50)51/h11,14,31,33-35,37,47,52H,1,9-10,12-13,15-28H2,2-8H3,(H,50,51)/t31-,33+,34-,35+,37+,41-,42+,43+,44-,45-/s2
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n/an/an/an/a 2.98n/an/an/an/a



VIIV HEALTHCARE UK (NO. 4) LIMITED

US Patent


Assay Description
MT-2 cells and 293T cells were obtained from the NIH AIDS Research and Reference Reagent Program. MT-2 cells were propagated in RPMI 1640 media suppl...


US Patent US10245275 (2019)

More data for this
Ligand-Target Pair
Gag-Pol polyprotein (Capsid Protein)


(Human immunodeficiency virus type 1 group M subtyp...)
BDBM372420
PNG
(US10245275, Compound 2b)
Show SMILES CC(=C)[C@@H]1CC[C@@]2(CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC=C(C6=CC[C@](CF)(CC6)OC=O)C(C)(C)[C@@H]5CC[C@@]34C)[C@@H]12)NCCN1CCS(=O)(=O)CC1
Show InChI InChI=1/C43H67FN2O4S/c1-30(2)32-12-19-43(45-22-23-46-24-26-51(48,49)27-25-46)21-20-40(6)34(37(32)43)8-9-36-39(5)15-13-33(38(3,4)35(39)14-16-41(36,40)7)31-10-17-42(28-44,18-11-31)50-29-47/h10,13,29,32,34-37,45H,1,8-9,11-12,14-28H2,2-7H3/t32-,34+,35-,36+,37+,39-,40+,41+,42+,43-/s2
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n/an/an/an/a 3n/an/an/an/a



VIIV HEALTHCARE UK (NO. 4) LIMITED

US Patent


Assay Description
MT-2 cells and 293T cells were obtained from the NIH AIDS Research and Reference Reagent Program. MT-2 cells were propagated in RPMI 1640 media suppl...


US Patent US10245275 (2019)

More data for this
Ligand-Target Pair
Gag-Pol polyprotein (Capsid Protein)


(Human immunodeficiency virus type 1 group M subtyp...)
BDBM372410
PNG
(Preparation of (S)-1-(fluoromethyl)-4-((1R,3aS,5aR...)
Show SMILES CC(=C)[C@@H]1CC[C@@]2(CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC=C(C6=CC[C@@](CF)(CC6)C(O)=O)C(C)(C)[C@@H]5CC[C@@]34C)[C@@H]12)NCCC1(O)CCC(CC1)OS(C)(=O)=O
Show InChI InChI=1/C46H72FNO6S/c1-30(2)33-15-24-46(48-28-27-45(51)22-13-32(14-23-45)54-55(8,52)53)26-25-42(6)35(38(33)46)9-10-37-41(5)18-16-34(40(3,4)36(41)17-19-43(37,42)7)31-11-20-44(29-47,21-12-31)39(49)50/h11,16,32-33,35-38,48,51H,1,9-10,12-15,17-29H2,2-8H3,(H,49,50)/t32?,33-,35+,36-,37+,38+,41-,42+,43+,44-,45?,46-/s2
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n/an/an/an/a 3.15n/an/an/an/a



VIIV HEALTHCARE UK (NO. 4) LIMITED

US Patent


Assay Description
MT-2 cells and 293T cells were obtained from the NIH AIDS Research and Reference Reagent Program. MT-2 cells were propagated in RPMI 1640 media suppl...


US Patent US10245275 (2019)

More data for this
Ligand-Target Pair
Gag-Pol polyprotein (Capsid Protein)


(Human immunodeficiency virus type 1 group M subtyp...)
BDBM372388
PNG
(Preparation of (S)-4-((1R,3aS,5aR,5bR,7aR,11aS,11b...)
Show SMILES CC(=C)[C@@H]1CC[C@@]2(CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC=C(C6=CC[C@@](CF)(CC6)C(O)=O)C(C)(C)[C@@H]5CC[C@@]34C)[C@@H]12)NCCS(=O)(=O)CCN1CCS(=O)(=O)CC1
Show InChI InChI=1/C45H71FN2O6S2/c1-31(2)33-12-19-45(47-22-26-55(51,52)27-23-48-24-28-56(53,54)29-25-48)21-20-42(6)35(38(33)45)8-9-37-41(5)15-13-34(40(3,4)36(41)14-16-43(37,42)7)32-10-17-44(30-46,18-11-32)39(49)50/h10,13,33,35-38,47H,1,8-9,11-12,14-30H2,2-7H3,(H,49,50)/t33-,35+,36-,37+,38+,41-,42+,43+,44-,45-/s2
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n/an/an/an/a 3.35n/an/an/an/a



VIIV HEALTHCARE UK (NO. 4) LIMITED

US Patent


Assay Description
MT-2 cells and 293T cells were obtained from the NIH AIDS Research and Reference Reagent Program. MT-2 cells were propagated in RPMI 1640 media suppl...


US Patent US10245275 (2019)

More data for this
Ligand-Target Pair
Gag-Pol polyprotein (Capsid Protein)


(Human immunodeficiency virus type 1 group M subtyp...)
BDBM372416
PNG
(US10245275, Compound A)
Show SMILES CC(=C)[C@@H]1CC[C@@]2(CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC=C(C6=CCC(F)(CC6)OC=O)C(C)(C)[C@@H]5CC[C@@]34C)[C@@H]12)NCCN1CCC(CC1)S(C)(=O)=O
Show InChI InChI=1/C44H69FN2O4S/c1-30(2)33-13-20-43(46-25-28-47-26-16-32(17-27-47)52(8,49)50)24-23-41(6)35(38(33)43)9-10-37-40(5)18-14-34(31-11-21-44(45,22-12-31)51-29-48)39(3,4)36(40)15-19-42(37,41)7/h11,14,29,32-33,35-38,46H,1,9-10,12-13,15-28H2,2-8H3/t33-,35+,36-,37+,38+,40-,41+,42+,43-,44?/s2
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n/an/an/an/a 4n/an/an/an/a



VIIV HEALTHCARE UK (NO. 4) LIMITED

US Patent


Assay Description
MT-2 cells and 293T cells were obtained from the NIH AIDS Research and Reference Reagent Program. MT-2 cells were propagated in RPMI 1640 media suppl...


US Patent US10245275 (2019)

More data for this
Ligand-Target Pair
Genome polyprotein


(Human enterovirus 71 (strain BrCr) (Ev 71))
BDBM50457114
PNG
(CHEMBL4204909)
Show SMILES CCO\N=C1/CCc2cc(OCCCCCN3CCN(c4ccnc(N)c4)S3(=O)=O)ccc12
Show InChI InChI=1S/C23H31N5O4S/c1-2-32-26-22-9-6-18-16-20(7-8-21(18)22)31-15-5-3-4-12-27-13-14-28(33(27,29)30)19-10-11-25-23(24)17-19/h7-8,10-11,16-17H,2-6,9,12-15H2,1H3,(H2,24,25)/b26-22+
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n/an/an/an/a 4n/an/an/an/a



WuXi AppTec (Shanghai) Co. Ltd

Curated by ChEMBL


Assay Description
Inhibition of Enterovirus 71 Shenzhen/120F1/09 capsid infected in human RD cells assessed as reduction in virus-induced cell death after 72 hrs by CC...


ACS Med Chem Lett 8: 841-846 (2017)

More data for this
Ligand-Target Pair
Gag-Pol polyprotein (Capsid Protein)


(Human immunodeficiency virus type 1 group M subtyp...)
BDBM372347
PNG
(Preparation of (S)-1-(fluoromethyl)-4-((1R,3aS,5aR...)
Show SMILES CC(=C)[C@@H]1CC[C@@]2(CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC=C(C6=CC[C@@](CF)(CC6)C(O)=O)C(C)(C)[C@@H]5CC[C@@]34C)[C@@H]12)NCCN1CCOCC1
Show InChI InChI=1/C43H67FN2O3/c1-29(2)31-12-19-43(45-22-23-46-24-26-49-27-25-46)21-20-40(6)33(36(31)43)8-9-35-39(5)15-13-32(38(3,4)34(39)14-16-41(35,40)7)30-10-17-42(28-44,18-11-30)37(47)48/h10,13,31,33-36,45H,1,8-9,11-12,14-28H2,2-7H3,(H,47,48)/t31-,33+,34-,35+,36+,39-,40+,41+,42-,43-/s2
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n/an/an/an/a 4.53n/an/an/an/a



VIIV HEALTHCARE UK (NO. 4) LIMITED

US Patent


Assay Description
MT-2 cells and 293T cells were obtained from the NIH AIDS Research and Reference Reagent Program. MT-2 cells were propagated in RPMI 1640 media suppl...


US Patent US10245275 (2019)

More data for this
Ligand-Target Pair
Gag-Pol polyprotein (Capsid Protein)


(Human immunodeficiency virus type 1 group M subtyp...)
BDBM372412
PNG
(Preparation of (S)-1-(fluoromethyl)-4-((1R,3aS,5aR...)
Show SMILES CC(=C)[C@@H]1CC[C@@]2(CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC=C(C6=CC[C@@](CF)(CC6)C(O)=O)C(C)(C)[C@@H]5CC[C@@]34C)[C@@H]12)NCCN1CCOC1=O
Show InChI InChI=1/C42H63FN2O4/c1-27(2)29-12-19-42(44-22-23-45-24-25-49-36(45)48)21-20-39(6)31(34(29)42)8-9-33-38(5)15-13-30(37(3,4)32(38)14-16-40(33,39)7)28-10-17-41(26-43,18-11-28)35(46)47/h10,13,29,31-34,44H,1,8-9,11-12,14-26H2,2-7H3,(H,46,47)/t29-,31+,32-,33+,34+,38-,39+,40+,41-,42-/s2
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n/an/an/an/a 5.30n/an/an/an/a



VIIV HEALTHCARE UK (NO. 4) LIMITED

US Patent


Assay Description
MT-2 cells and 293T cells were obtained from the NIH AIDS Research and Reference Reagent Program. MT-2 cells were propagated in RPMI 1640 media suppl...


US Patent US10245275 (2019)

More data for this
Ligand-Target Pair
Gag-Pol polyprotein (Capsid Protein)


(Human immunodeficiency virus type 1 group M subtyp...)
BDBM372415
PNG
(Preparation of (S)-4-((1R,3aS,5aR,5bR,7aR,11aS,11b...)
Show SMILES CC(=C)[C@@H]1CC[C@@]2(CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC=C(C6=CC[C@@](CF)(CC6)C(O)=O)C(C)(C)[C@@H]5CC[C@@]34C)[C@@H]12)NCCN1CCN(C(C)=O)C(C)(C)C1=O
Show InChI InChI=1/C47H72FN3O4/c1-30(2)33-15-22-47(49-25-26-50-27-28-51(31(3)52)42(6,7)39(50)53)24-23-44(9)35(38(33)47)11-12-37-43(8)18-16-34(41(4,5)36(43)17-19-45(37,44)10)32-13-20-46(29-48,21-14-32)40(54)55/h13,16,33,35-38,49H,1,11-12,14-15,17-29H2,2-10H3,(H,54,55)/t33-,35+,36-,37+,38+,43-,44+,45+,46-,47-/s2
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n/an/an/an/a 5.77n/an/an/an/a



VIIV HEALTHCARE UK (NO. 4) LIMITED

US Patent


Assay Description
MT-2 cells and 293T cells were obtained from the NIH AIDS Research and Reference Reagent Program. MT-2 cells were propagated in RPMI 1640 media suppl...


US Patent US10245275 (2019)

More data for this
Ligand-Target Pair
Gag-Pol polyprotein (Capsid Protein)


(Human immunodeficiency virus type 1 group M subtyp...)
BDBM372394
PNG
(Preparation of (S)-4-((1R,3aS,5aR,5bR,7aR,11aS,11b...)
Show SMILES CC(=C)[C@@H]1CC[C@@]2(CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC=C(C6=CC[C@@](CF)(CC6)C(O)=O)C(C)(C)[C@@H]5CC[C@@]34C)[C@@H]12)NCC=C(C1CC1)C1CC1
Show InChI InChI=1/C46H68FNO2/c1-29(2)33-16-24-46(48-27-19-34(30-8-9-30)31-10-11-31)26-25-43(6)36(39(33)46)12-13-38-42(5)20-17-35(41(3,4)37(42)18-21-44(38,43)7)32-14-22-45(28-47,23-15-32)40(49)50/h14,17,19,30-31,33,36-39,48H,1,8-13,15-16,18,20-28H2,2-7H3,(H,49,50)/t33-,36+,37-,38+,39+,42-,43+,44+,45-,46-/s2
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n/an/an/an/a 11n/an/an/an/a



VIIV HEALTHCARE UK (NO. 4) LIMITED

US Patent


Assay Description
MT-2 cells and 293T cells were obtained from the NIH AIDS Research and Reference Reagent Program. MT-2 cells were propagated in RPMI 1640 media suppl...


US Patent US10245275 (2019)

More data for this
Ligand-Target Pair
Genome polyprotein


(Human enterovirus 71 (strain BrCr) (Ev 71))
BDBM50457109
PNG
(CHEMBL4203068)
Show SMILES Nc1cc(ccn1)N1CCN(CCCCCOc2ccc(cc2)-c2ccc(Cl)cc2)S1(=O)=O
Show InChI InChI=1S/C24H27ClN4O3S/c25-21-8-4-19(5-9-21)20-6-10-23(11-7-20)32-17-3-1-2-14-28-15-16-29(33(28,30)31)22-12-13-27-24(26)18-22/h4-13,18H,1-3,14-17H2,(H2,26,27)
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n/an/an/an/a 12n/an/an/an/a



WuXi AppTec (Shanghai) Co. Ltd

Curated by ChEMBL


Assay Description
Inhibition of Enterovirus 71 Shenzhen/120F1/09 capsid infected in human RD cells assessed as reduction in virus-induced cell death after 72 hrs by CC...


ACS Med Chem Lett 8: 841-846 (2017)

More data for this
Ligand-Target Pair
Gag-Pol polyprotein (Capsid Protein)


(Human immunodeficiency virus type 1 group M subtyp...)
BDBM372357
PNG
(Preparation of (R)-4-((1R,3aS,5aR,5bR,7aR,11aS,11b...)
Show SMILES CCOC(=O)C1(CCN(CCN[C@]23CC[C@H]([C@@H]2[C@H]2CC[C@@H]4[C@@]5(C)CC=C(C6=CC[C@](CF)(CC6)C(O)=O)C(C)(C)[C@@H]5CC[C@@]4(C)[C@]2(C)CC3)C(C)=C)CC1)C(=O)OCC
Show InChI InChI=1/C50H77FN2O6/c1-10-58-42(56)49(43(57)59-11-2)26-29-53(30-27-49)31-28-52-50-23-16-35(33(3)4)40(50)37-12-13-39-45(7)19-17-36(34-14-21-48(32-51,22-15-34)41(54)55)44(5,6)38(45)18-20-47(39,9)46(37,8)24-25-50/h14,17,35,37-40,52H,3,10-13,15-16,18-32H2,1-2,4-9H3,(H,54,55)/t35-,37+,38-,39+,40+,45-,46+,47+,48+,50-/s2
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n/an/an/an/a 18.8n/an/an/an/a



VIIV HEALTHCARE UK (NO. 4) LIMITED

US Patent


Assay Description
MT-2 cells and 293T cells were obtained from the NIH AIDS Research and Reference Reagent Program. MT-2 cells were propagated in RPMI 1640 media suppl...


US Patent US10245275 (2019)

More data for this
Ligand-Target Pair
Gag-Pol polyprotein (Capsid Protein)


(Human immunodeficiency virus type 1 group M subtyp...)
BDBM372361
PNG
(Preparation of 1-(2-(((1R,3aS,5aR,5bR,7aR,11aS,11b...)
Show SMILES CCOC(=O)C1(CCN(CCN[C@]23CC[C@H]([C@@H]2[C@H]2CC[C@@H]4[C@@]5(C)CC=C(C6=CC[C@](CF)(CC6)C(O)=O)C(C)(C)[C@@H]5CC[C@@]4(C)[C@]2(C)CC3)C(C)=C)CC1)C(O)=O
Show InChI InChI=1/C48H73FN2O6/c1-9-57-41(56)47(40(54)55)24-27-51(28-25-47)29-26-50-48-21-14-33(31(2)3)38(48)35-10-11-37-43(6)17-15-34(32-12-19-46(30-49,20-13-32)39(52)53)42(4,5)36(43)16-18-45(37,8)44(35,7)22-23-48/h12,15,33,35-38,50H,2,9-11,13-14,16-30H2,1,3-8H3,(H,52,53)(H,54,55)/t33-,35+,36-,37+,38+,43-,44+,45+,46+,48-/s2
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n/an/an/an/a 19.4n/an/an/an/a



VIIV HEALTHCARE UK (NO. 4) LIMITED

US Patent


Assay Description
MT-2 cells and 293T cells were obtained from the NIH AIDS Research and Reference Reagent Program. MT-2 cells were propagated in RPMI 1640 media suppl...


US Patent US10245275 (2019)

More data for this
Ligand-Target Pair
Gag-Pol polyprotein (Capsid Protein)


(Human immunodeficiency virus type 1 group M subtyp...)
BDBM372362
PNG
(Preparation of 4-(2-(((1R,3aS,5aR,5bR,7aR,11aS,11b...)
Show SMILES CC(=C)[C@@H]1CC[C@@]2(CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC=C(C6=CC[C@](CF)(CC6)C(O)=O)C(C)(C)[C@@H]5CC[C@@]34C)[C@@H]12)NCCN1CCSCC1C(O)=O
Show InChI InChI=1/C44H67FN2O4S/c1-28(2)30-12-19-44(46-22-23-47-24-25-52-26-33(47)37(48)49)21-20-41(6)32(36(30)44)8-9-35-40(5)15-13-31(39(3,4)34(40)14-16-42(35,41)7)29-10-17-43(27-45,18-11-29)38(50)51/h10,13,30,32-36,46H,1,8-9,11-12,14-27H2,2-7H3,(H,48,49)(H,50,51)/t30-,32+,33?,34-,35+,36+,40-,41+,42+,43+,44-/s2
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n/an/an/an/a 24.3n/an/an/an/a



VIIV HEALTHCARE UK (NO. 4) LIMITED

US Patent


Assay Description
MT-2 cells and 293T cells were obtained from the NIH AIDS Research and Reference Reagent Program. MT-2 cells were propagated in RPMI 1640 media suppl...


US Patent US10245275 (2019)

More data for this
Ligand-Target Pair
Gag-Pol polyprotein (Capsid Protein)


(Human immunodeficiency virus type 1 group M subtyp...)
BDBM372384
PNG
(US10245275, Example 39 | US10245275, Example 40)
Show SMILES CC(=C)[C@@H]1CC[C@@]2(CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC=C(C6=CC[C@@](CF)(CC6)C(O)=O)C(C)(C)[C@@H]5CC[C@@]34C)[C@@H]12)NC(CN)C(F)(F)F
Show InChI InChI=1/C40H60F4N2O2/c1-24(2)26-12-19-39(46-31(22-45)40(42,43)44)21-20-36(6)28(32(26)39)8-9-30-35(5)15-13-27(34(3,4)29(35)14-16-37(30,36)7)25-10-17-38(23-41,18-11-25)33(47)48/h10,13,26,28-32,46H,1,8-9,11-12,14-23,45H2,2-7H3,(H,47,48)/t26-,28+,29-,30+,31?,32+,35-,36+,37+,38-,39-/s2
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n/an/an/an/a 47.3n/an/an/an/a



VIIV HEALTHCARE UK (NO. 4) LIMITED

US Patent


Assay Description
MT-2 cells and 293T cells were obtained from the NIH AIDS Research and Reference Reagent Program. MT-2 cells were propagated in RPMI 1640 media suppl...


US Patent US10245275 (2019)

More data for this
Ligand-Target Pair
Genome polyprotein


(Human enterovirus 71 (strain BrCr) (Ev 71))
BDBM50457110
PNG
(CHEMBL4216835)
Show SMILES Clc1ccc(cc1)-c1ccc2OC(CCCCN3CCN(C3=O)c3ccncc3)CCc2c1
Show InChI InChI=1S/C27H28ClN3O2/c28-23-8-4-20(5-9-23)21-7-11-26-22(19-21)6-10-25(33-26)3-1-2-16-30-17-18-31(27(30)32)24-12-14-29-15-13-24/h4-5,7-9,11-15,19,25H,1-3,6,10,16-18H2
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n/an/an/an/a 48n/an/an/an/a



WuXi AppTec (Shanghai) Co. Ltd

Curated by ChEMBL


Assay Description
Inhibition of Enterovirus 71 Shenzhen/120F1/09 capsid infected in human RD cells assessed as reduction in virus-induced cell death after 72 hrs by CC...


ACS Med Chem Lett 8: 841-846 (2017)

More data for this
Ligand-Target Pair
Gag-Pol polyprotein (Capsid Protein)


(Human immunodeficiency virus type 1 group M subtyp...)
BDBM372381
PNG
(Preparation of (1S)-1-(fluoromethyl)-4-((1R,3aS,5a...)
Show SMILES CC(=C)[C@@H]1CC[C@@]2(CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC=C(C6=CC[C@@](CF)(CC6)C(O)=O)C(C)(C)[C@@H]5CC[C@@]34C)[C@@H]12)NCC(=O)N1CCC(C1)S(C)(=O)=O
Show InChI InChI=1/C44H67FN2O5S/c1-28(2)31-13-21-44(46-25-36(48)47-24-16-30(26-47)53(8,51)52)23-22-41(6)33(37(31)44)9-10-35-40(5)17-14-32(39(3,4)34(40)15-18-42(35,41)7)29-11-19-43(27-45,20-12-29)38(49)50/h11,14,30-31,33-35,37,46H,1,9-10,12-13,15-27H2,2-8H3,(H,49,50)/t30?,31-,33+,34-,35+,37+,40-,41+,42+,43-,44-/s2
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n/an/an/an/a<50n/an/an/an/a



VIIV HEALTHCARE UK (NO. 4) LIMITED

US Patent


Assay Description
MT-2 cells and 293T cells were obtained from the NIH AIDS Research and Reference Reagent Program. MT-2 cells were propagated in RPMI 1640 media suppl...


US Patent US10245275 (2019)

More data for this
Ligand-Target Pair
Gag-Pol polyprotein (Capsid Protein)


(Human immunodeficiency virus type 1 group M subtyp...)
BDBM372382
PNG
(Preparation of (S)-4-((1R,3aS,5aR,5bR,7aR,11aS,11b...)
Show SMILES CC(=C)[C@@H]1CC[C@@]2(CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC=C(C6=CC[C@@](CF)(CC6)C(O)=O)C(C)(C)[C@@H]5CC[C@@]34C)[C@@H]12)NCC(=O)N1C[C@@H]2C[C@H]1CS2(=O)=O
Show InChI InChI=1/C44H65FN2O5S/c1-27(2)31-12-19-44(46-23-36(48)47-24-30-22-29(47)25-53(30,51)52)21-20-41(6)33(37(31)44)8-9-35-40(5)15-13-32(39(3,4)34(40)14-16-42(35,41)7)28-10-17-43(26-45,18-11-28)38(49)50/h10,13,29-31,33-35,37,46H,1,8-9,11-12,14-26H2,2-7H3,(H,49,50)/t29-,30-,31-,33+,34-,35+,37+,40-,41+,42+,43-,44-/s2
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n/an/an/an/a<50n/an/an/an/a



VIIV HEALTHCARE UK (NO. 4) LIMITED

US Patent


Assay Description
MT-2 cells and 293T cells were obtained from the NIH AIDS Research and Reference Reagent Program. MT-2 cells were propagated in RPMI 1640 media suppl...


US Patent US10245275 (2019)

More data for this
Ligand-Target Pair
Gag-Pol polyprotein (Capsid Protein)


(Human immunodeficiency virus type 1 group M subtyp...)
BDBM372383
PNG
(Preparation of (R)-4-((1R,3aS,5aR,5bR,7aR,11aS,11b...)
Show SMILES CC(=C)[C@@H]1CC[C@@]2(CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC=C(C6=CC[C@](CF)(CC6)C(O)=O)C(C)(C)[C@@H]5CC[C@@]34C)[C@@H]12)C(=O)NCCN1CCS(=O)(=O)CC1
Show InChI InChI=1/C44H67FN2O5S/c1-29(2)31-12-19-44(37(48)46-22-23-47-24-26-53(51,52)27-25-47)21-20-41(6)33(36(31)44)8-9-35-40(5)15-13-32(39(3,4)34(40)14-16-42(35,41)7)30-10-17-43(28-45,18-11-30)38(49)50/h10,13,31,33-36H,1,8-9,11-12,14-28H2,2-7H3,(H,46,48)(H,49,50)/t31-,33+,34-,35+,36+,40-,41+,42+,43+,44-/s2
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n/an/an/an/a<50n/an/an/an/a



VIIV HEALTHCARE UK (NO. 4) LIMITED

US Patent


Assay Description
MT-2 cells and 293T cells were obtained from the NIH AIDS Research and Reference Reagent Program. MT-2 cells were propagated in RPMI 1640 media suppl...


US Patent US10245275 (2019)

More data for this
Ligand-Target Pair
Gag-Pol polyprotein (Capsid Protein)


(Human immunodeficiency virus type 1 group M subtyp...)
BDBM372386
PNG
(Preparation of (1S)-4-((1R,3aS,5aR,5bR,7aR,11aS,11...)
Show SMILES CC(=C)[C@@H]1CC[C@@]2(CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC=C(C6=CC[C@@](CF)(CC6)C(O)=O)C(C)(C)[C@@H]5CC[C@@]34C)[C@@H]12)NC(CN1CCS(=O)(=O)CC1)C(F)(F)F
Show InChI InChI=1/C44H66F4N2O4S/c1-28(2)30-12-19-43(49-35(44(46,47)48)26-50-22-24-55(53,54)25-23-50)21-20-40(6)32(36(30)43)8-9-34-39(5)15-13-31(38(3,4)33(39)14-16-41(34,40)7)29-10-17-42(27-45,18-11-29)37(51)52/h10,13,30,32-36,49H,1,8-9,11-12,14-27H2,2-7H3,(H,51,52)/t30-,32+,33-,34+,35?,36+,39-,40+,41+,42-,43-/s2
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n/an/an/an/a>50n/an/an/an/a



VIIV HEALTHCARE UK (NO. 4) LIMITED

US Patent


Assay Description
MT-2 cells and 293T cells were obtained from the NIH AIDS Research and Reference Reagent Program. MT-2 cells were propagated in RPMI 1640 media suppl...


US Patent US10245275 (2019)

More data for this
Ligand-Target Pair
Gag-Pol polyprotein (Capsid Protein)


(Human immunodeficiency virus type 1 group M subtyp...)
BDBM372386
PNG
(Preparation of (1S)-4-((1R,3aS,5aR,5bR,7aR,11aS,11...)
Show SMILES CC(=C)[C@@H]1CC[C@@]2(CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC=C(C6=CC[C@@](CF)(CC6)C(O)=O)C(C)(C)[C@@H]5CC[C@@]34C)[C@@H]12)NC(CN1CCS(=O)(=O)CC1)C(F)(F)F
Show InChI InChI=1/C44H66F4N2O4S/c1-28(2)30-12-19-43(49-35(44(46,47)48)26-50-22-24-55(53,54)25-23-50)21-20-40(6)32(36(30)43)8-9-34-39(5)15-13-31(38(3,4)33(39)14-16-41(34,40)7)29-10-17-42(27-45,18-11-29)37(51)52/h10,13,30,32-36,49H,1,8-9,11-12,14-27H2,2-7H3,(H,51,52)/t30-,32+,33-,34+,35?,36+,39-,40+,41+,42-,43-/s2
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
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PC cid
PC sid
UniChem
US Patent
n/an/an/an/a>50n/an/an/an/a



VIIV HEALTHCARE UK (NO. 4) LIMITED

US Patent


Assay Description
MT-2 cells and 293T cells were obtained from the NIH AIDS Research and Reference Reagent Program. MT-2 cells were propagated in RPMI 1640 media suppl...


US Patent US10245275 (2019)

More data for this
Ligand-Target Pair
Gag-Pol polyprotein (Capsid Protein)


(Human immunodeficiency virus type 1 group M subtyp...)
BDBM372389
PNG
(Preparation of (S)-1-(fluoromethyl)-4-((1R,3aS,5aR...)
Show SMILES CC(=C)[C@@H]1CC[C@@]2(CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC=C(C6=CC[C@@](CF)(CC6)C(O)=O)C(C)(C)[C@@H]5CC[C@@]34C)[C@@H]12)NCCC(C)(C)O
Show InChI InChI=1/C42H66FNO3/c1-27(2)29-14-21-42(44-25-24-36(3,4)47)23-22-39(8)31(34(29)42)10-11-33-38(7)17-15-30(37(5,6)32(38)16-18-40(33,39)9)28-12-19-41(26-43,20-13-28)35(45)46/h12,15,29,31-34,44,47H,1,10-11,13-14,16-26H2,2-9H3,(H,45,46)/t29-,31+,32-,33+,34+,38-,39+,40+,41-,42-/s2
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a<50n/an/an/an/a



VIIV HEALTHCARE UK (NO. 4) LIMITED

US Patent


Assay Description
MT-2 cells and 293T cells were obtained from the NIH AIDS Research and Reference Reagent Program. MT-2 cells were propagated in RPMI 1640 media suppl...


US Patent US10245275 (2019)

More data for this
Ligand-Target Pair
Gag-Pol polyprotein (Capsid Protein)


(Human immunodeficiency virus type 1 group M subtyp...)
BDBM372390
PNG
(Preparation of | US10245275, Example 2-2)
Show SMILES CC(=C)[C@@H]1CC[C@@]2(CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC=C(C6=CC[C@@](CF)(CC6)C(O)=O)C(C)(C)[C@@H]5CC[C@@]34C)[C@@H]12)NCC(C)(C)O
Show InChI InChI=1/C41H64FNO3/c1-26(2)28-14-21-41(43-25-35(3,4)46)23-22-38(8)30(33(28)41)10-11-32-37(7)17-15-29(36(5,6)31(37)16-18-39(32,38)9)27-12-19-40(24-42,20-13-27)34(44)45/h12,15,28,30-33,43,46H,1,10-11,13-14,16-25H2,2-9H3,(H,44,45)/t28-,30+,31-,32+,33+,37-,38+,39+,40-,41-/s2
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a<50n/an/an/an/a



VIIV HEALTHCARE UK (NO. 4) LIMITED

US Patent


Assay Description
MT-2 cells and 293T cells were obtained from the NIH AIDS Research and Reference Reagent Program. MT-2 cells were propagated in RPMI 1640 media suppl...


US Patent US10245275 (2019)

More data for this
Ligand-Target Pair
Gag-Pol polyprotein (Capsid Protein)


(Human immunodeficiency virus type 1 group M subtyp...)
BDBM372391
PNG
(Preparation of (S)-1-(fluoromethyl)-4-((1R,3aS,5aR...)
Show SMILES CC(=C)[C@@H]1CC[C@@]2(CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC=C(C6=CC[C@@](CF)(CC6)C(O)=O)C(C)(C)[C@@H]5CC[C@@]34C)[C@@H]12)NCCCC(C)(C)O
Show InChI InChI=1/C43H68FNO3/c1-28(2)30-15-23-43(45-26-10-18-37(3,4)48)25-24-40(8)32(35(30)43)11-12-34-39(7)19-16-31(38(5,6)33(39)17-20-41(34,40)9)29-13-21-42(27-44,22-14-29)36(46)47/h13,16,30,32-35,45,48H,1,10-12,14-15,17-27H2,2-9H3,(H,46,47)/t30-,32+,33-,34+,35+,39-,40+,41+,42-,43-/s2
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a<50n/an/an/an/a



VIIV HEALTHCARE UK (NO. 4) LIMITED

US Patent


Assay Description
MT-2 cells and 293T cells were obtained from the NIH AIDS Research and Reference Reagent Program. MT-2 cells were propagated in RPMI 1640 media suppl...


US Patent US10245275 (2019)

More data for this
Ligand-Target Pair
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