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Compile Data Set for Download or QSAR

Found 45564 hits Enz. Inhib. hit(s) with Target = 'DOPAMINE'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Dopamine D1 and D2 receptor


(Homo sapiens (Human))
BDBM49058
PNG
(3-[(2-keto-3,4-dihydro-1H-quinolin-6-yl)sulfonylam...)
Show SMILES O=C(CCNS(=O)(=O)c1ccc2NC(=O)CCc2c1)NCc1ccc2OCOc2c1
Show InChI InChI=1S/C20H21N3O6S/c24-19(21-11-13-1-5-17-18(9-13)29-12-28-17)7-8-22-30(26,27)15-3-4-16-14(10-15)2-6-20(25)23-16/h1,3-5,9-10,22H,2,6-8,11-12H2,(H,21,24)(H,23,25)
KEGG

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n/an/an/an/a 0.00000188n/an/an/an/a



Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters

Curated by PubChem BioAssay


Assay Description
Assay Provider: Val Watts Assay Provider Affiliation: Purdue University Grant Title: Allosteric Modulators of D1 Receptors Grant Number: 1 X01 MH0776...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q2H41PVH
More data for this
Ligand-Target Pair
Dopamine D1 and D2 receptor


(Homo sapiens (Human))
BDBM48990
PNG
(Cyclopropanecarboxylic acid (6-butyrylamino-pyridi...)
Show SMILES CCCC(=O)Nc1ccc(NC(=O)C2CC2)cn1
Show InChI InChI=1S/C13H17N3O2/c1-2-3-12(17)16-11-7-6-10(8-14-11)15-13(18)9-4-5-9/h6-9H,2-5H2,1H3,(H,15,18)(H,14,16,17)
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n/an/an/an/a 0.0000224n/an/an/an/a



Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters

Curated by PubChem BioAssay


Assay Description
Assay Provider: Val Watts Assay Provider Affiliation: Purdue University Grant Title: Allosteric Modulators of D1 Receptors Grant Number: 1 X01 MH0776...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q2H41PVH
More data for this
Ligand-Target Pair
Dopamine D5 receptor


(Homo sapiens (Human))
BDBM48941
PNG
(4-hydroxy-6-(4-isopropylphenyl)-2-piperidin-1-ylpy...)
Show SMILES CC(C)c1ccc(cc1)-c1nc([nH]c(=O)c1C#N)N1CCCCC1
Show InChI InChI=1S/C19H22N4O/c1-13(2)14-6-8-15(9-7-14)17-16(12-20)18(24)22-19(21-17)23-10-4-3-5-11-23/h6-9,13H,3-5,10-11H2,1-2H3,(H,21,22,24)
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n/an/an/an/a 0.0000236n/an/an/an/a



Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters

Curated by PubChem BioAssay


Assay Description
Assay Provider: Val Watts Assay Provider Affiliation: Purdue University Grant Title: Allosteric Modulators of D1 Receptors Grant Number: 1 X01 MH0776...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q2MW2FJG
More data for this
Ligand-Target Pair
Dopamine D5 receptor


(Homo sapiens (Human))
BDBM48969
PNG
(MLS000115755 | SMR000092778 | [3-amino-4-(methoxym...)
Show SMILES COCc1cc(C)nc2sc(C(=O)N3CCN(CC3)c3ccccc3)c(N)c12
Show InChI InChI=1S/C21H24N4O2S/c1-14-12-15(13-27-2)17-18(22)19(28-20(17)23-14)21(26)25-10-8-24(9-11-25)16-6-4-3-5-7-16/h3-7,12H,8-11,13,22H2,1-2H3
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n/an/an/an/a 0.000212n/an/an/an/a



Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters

Curated by PubChem BioAssay


Assay Description
Assay Provider: Val Watts Assay Provider Affiliation: Purdue University Grant Title: Allosteric Modulators of D1 Receptors Grant Number: 1 X01 MH0776...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q2MW2FJG
More data for this
Ligand-Target Pair
Dopamine D1 and D2 receptor


(Homo sapiens (Human))
BDBM49018
PNG
(2-[2-[3-(3,4-dimethoxyphenyl)-1,2,4-oxadiazol-5-yl...)
Show SMILES COc1ccc(cc1OC)-c1noc(CCN2C(=O)c3ccccc3C2=O)n1
Show InChI InChI=1S/C20H17N3O5/c1-26-15-8-7-12(11-16(15)27-2)18-21-17(28-22-18)9-10-23-19(24)13-5-3-4-6-14(13)20(23)25/h3-8,11H,9-10H2,1-2H3
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n/an/an/an/a 0.000309n/an/an/an/a



Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters

Curated by PubChem BioAssay


Assay Description
Assay Provider: Val Watts Assay Provider Affiliation: Purdue University Grant Title: Allosteric Modulators of D1 Receptors Grant Number: 1 X01 MH0776...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q2H41PVH
More data for this
Ligand-Target Pair
Dopamine D1 and D2 receptor


(Homo sapiens (Human))
BDBM49050
PNG
(3,4-dimethoxy-N-[5-(2-thenyl)-1,3,4-thiadiazol-2-y...)
Show SMILES COc1ccc(cc1OC)C(=O)Nc1nnc(Cc2cccs2)s1
Show InChI InChI=1S/C16H15N3O3S2/c1-21-12-6-5-10(8-13(12)22-2)15(20)17-16-19-18-14(24-16)9-11-4-3-7-23-11/h3-8H,9H2,1-2H3,(H,17,19,20)
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n/an/an/an/a 0.000313n/an/an/an/a



Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters

Curated by PubChem BioAssay


Assay Description
Assay Provider: Val Watts Assay Provider Affiliation: Purdue University Grant Title: Allosteric Modulators of D1 Receptors Grant Number: 1 X01 MH0776...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q2H41PVH
More data for this
Ligand-Target Pair
Dopamine D5 receptor


(Homo sapiens (Human))
BDBM48902
PNG
(2-[5-(3,4-Diethoxy-phenyl)-tetrazol-2-yl]-N-(4-met...)
Show SMILES CCOc1ccc(cc1OCC)-c1nnn(CC(=O)NCc2ccc(OC)cc2)n1
Show InChI InChI=1S/C21H25N5O4/c1-4-29-18-11-8-16(12-19(18)30-5-2)21-23-25-26(24-21)14-20(27)22-13-15-6-9-17(28-3)10-7-15/h6-12H,4-5,13-14H2,1-3H3,(H,22,27)
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n/an/an/an/a 0.000473n/an/an/an/a



Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters

Curated by PubChem BioAssay


Assay Description
Assay Provider: Val Watts Assay Provider Affiliation: Purdue University Grant Title: Allosteric Modulators of D1 Receptors Grant Number: 1 X01 MH0776...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q2MW2FJG
More data for this
Ligand-Target Pair
Dopamine D5 receptor


(Homo sapiens (Human))
BDBM48929
PNG
(2-N-(4-methoxyphenyl)-6-[(1-methyltetrazol-5-yl)su...)
Show SMILES COc1ccc(Nc2nc(N)nc(CSc3nnnn3C)n2)cc1
Show InChI InChI=1S/C13H15N9OS/c1-22-13(19-20-21-22)24-7-10-16-11(14)18-12(17-10)15-8-3-5-9(23-2)6-4-8/h3-6H,7H2,1-2H3,(H3,14,15,16,17,18)
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n/an/an/an/a 0.000516n/an/an/an/a



Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters

Curated by PubChem BioAssay


Assay Description
Assay Provider: Val Watts Assay Provider Affiliation: Purdue University Grant Title: Allosteric Modulators of D1 Receptors Grant Number: 1 X01 MH0776...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q2MW2FJG
More data for this
Ligand-Target Pair
Dopamine D5 receptor


(Homo sapiens (Human))
BDBM48966
PNG
(1-(3-amino-7-methoxy-1-pyrazolo[3,4-b]quinolinyl)-...)
Show SMILES COc1ccc2cc3c(N)nn(C(=O)Cc4ccccc4OC)c3nc2c1
Show InChI InChI=1S/C20H18N4O3/c1-26-14-8-7-12-9-15-19(21)23-24(20(15)22-16(12)11-14)18(25)10-13-5-3-4-6-17(13)27-2/h3-9,11H,10H2,1-2H3,(H2,21,23)
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n/an/an/an/a 0.000635n/an/an/an/a



Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters

Curated by PubChem BioAssay


Assay Description
Assay Provider: Val Watts Assay Provider Affiliation: Purdue University Grant Title: Allosteric Modulators of D1 Receptors Grant Number: 1 X01 MH0776...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q2MW2FJG
More data for this
Ligand-Target Pair
Dopamine D5 receptor


(Homo sapiens (Human))
BDBM48911
PNG
(1-(5-Chloro-2-methoxy-phenyl)-2-(1-cyclopentyl-1H-...)
Show SMILES COc1ccc(Cl)cc1C(=O)CSc1nnnn1C1CCCC1
Show InChI InChI=1S/C15H17ClN4O2S/c1-22-14-7-6-10(16)8-12(14)13(21)9-23-15-17-18-19-20(15)11-4-2-3-5-11/h6-8,11H,2-5,9H2,1H3
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n/an/an/an/a 0.000661n/an/an/an/a



Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters

Curated by PubChem BioAssay


Assay Description
Assay Provider: Val Watts Assay Provider Affiliation: Purdue University Grant Title: Allosteric Modulators of D1 Receptors Grant Number: 1 X01 MH0776...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q2MW2FJG
More data for this
Ligand-Target Pair
Dopamine D5 receptor


(Homo sapiens (Human))
BDBM48957
PNG
((5Z)-2-(1-azepanyl)-5-(7-bromo-5-methyl-2-oxo-1H-i...)
Show SMILES Cc1cc2\C(C(=O)Nc2c(Br)c1)=C1\SC(=NC1=O)N1CCCCCC1
Show InChI InChI=1S/C18H18BrN3O2S/c1-10-8-11-13(16(23)20-14(11)12(19)9-10)15-17(24)21-18(25-15)22-6-4-2-3-5-7-22/h8-9H,2-7H2,1H3,(H,20,23)/b15-13-
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n/an/an/an/a 0.00103n/an/an/an/a



Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters

Curated by PubChem BioAssay


Assay Description
Assay Provider: Val Watts Assay Provider Affiliation: Purdue University Grant Title: Allosteric Modulators of D1 Receptors Grant Number: 1 X01 MH0776...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q2MW2FJG
More data for this
Ligand-Target Pair
Dopamine D5 receptor


(Homo sapiens (Human))
BDBM48978
PNG
(2-(4-fluorophenyl)-5-[(phenylmethyl)amino]-1,3-oxa...)
Show SMILES Fc1ccc(cc1)-c1nc(C#N)c(NCc2ccccc2)o1
Show InChI InChI=1S/C17H12FN3O/c18-14-8-6-13(7-9-14)16-21-15(10-19)17(22-16)20-11-12-4-2-1-3-5-12/h1-9,20H,11H2
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n/an/an/an/a 0.00105n/an/an/an/a



Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters

Curated by PubChem BioAssay


Assay Description
Assay Provider: Val Watts Assay Provider Affiliation: Purdue University Grant Title: Allosteric Modulators of D1 Receptors Grant Number: 1 X01 MH0776...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q2MW2FJG
More data for this
Ligand-Target Pair
Dopamine D5 receptor


(Homo sapiens (Human))
BDBM48950
PNG
(1-butyl-5-keto-2-nicotinoylimino-dipyrido[1,2-d:3'...)
Show SMILES CCCCn1c2nc3ccccn3c(=O)c2cc(C(=O)OCC)\c1=N/C(=O)c1cccnc1
Show InChI InChI=1S/C24H23N5O4/c1-3-5-12-29-20-17(23(31)28-13-7-6-10-19(28)26-20)14-18(24(32)33-4-2)21(29)27-22(30)16-9-8-11-25-15-16/h6-11,13-15H,3-5,12H2,1-2H3/b27-21+
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n/an/an/an/a 0.00107n/an/an/an/a



Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters

Curated by PubChem BioAssay


Assay Description
Assay Provider: Val Watts Assay Provider Affiliation: Purdue University Grant Title: Allosteric Modulators of D1 Receptors Grant Number: 1 X01 MH0776...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q2MW2FJG
More data for this
Ligand-Target Pair
Dopamine D5 receptor


(Homo sapiens (Human))
BDBM48968
PNG
(2-[4-[[3-(3,5-dimethyl-1-pyrazolyl)-2-quinoxalinyl...)
Show SMILES Cc1cc(C)n(n1)-c1nc2ccccc2nc1Nc1ccc(CC(O)=O)cc1
Show InChI InChI=1S/C21H19N5O2/c1-13-11-14(2)26(25-13)21-20(23-17-5-3-4-6-18(17)24-21)22-16-9-7-15(8-10-16)12-19(27)28/h3-11H,12H2,1-2H3,(H,22,23)(H,27,28)
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n/an/an/an/a 0.00111n/an/an/an/a



Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters

Curated by PubChem BioAssay


Assay Description
Assay Provider: Val Watts Assay Provider Affiliation: Purdue University Grant Title: Allosteric Modulators of D1 Receptors Grant Number: 1 X01 MH0776...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q2MW2FJG
More data for this
Ligand-Target Pair
Dopamine D1 and D2 receptor


(Homo sapiens (Human))
BDBM39938
PNG
(6-cyclohexyl-3-(1,4,5,6-tetrahydrocyclopenta[c]pyr...)
Show SMILES C1Cc2[nH]nc(c2C1)-c1nnc2sc(nn12)C1CCCCC1
Show InChI InChI=1S/C15H18N6S/c1-2-5-9(6-3-1)14-20-21-13(18-19-15(21)22-14)12-10-7-4-8-11(10)16-17-12/h9H,1-8H2,(H,16,17)
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n/an/an/an/a 0.00114n/an/an/an/a



Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters

Curated by PubChem BioAssay


Assay Description
Assay Provider: Val Watts Assay Provider Affiliation: Purdue University Grant Title: Allosteric Modulators of D1 Receptors Grant Number: 1 X01 MH0776...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q2H41PVH
More data for this
Ligand-Target Pair
Dopamine D1 and D2 receptor


(Homo sapiens (Human))
BDBM49075
PNG
(2-(allylamino)-4-amino-5-(2,2-dimethylpropanoyl)-3...)
Show SMILES CC(C)(C)C(=O)c1sc(NCC=C)c(C#N)c1N
Show InChI InChI=1S/C13H17N3OS/c1-5-6-16-12-8(7-14)9(15)10(18-12)11(17)13(2,3)4/h5,16H,1,6,15H2,2-4H3
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n/an/an/an/a 0.00114n/an/an/an/a



Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters

Curated by PubChem BioAssay


Assay Description
Assay Provider: Val Watts Assay Provider Affiliation: Purdue University Grant Title: Allosteric Modulators of D1 Receptors Grant Number: 1 X01 MH0776...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q2H41PVH
More data for this
Ligand-Target Pair
Dopamine D1 and D2 receptor


(Homo sapiens (Human))
BDBM49037
PNG
(4-amino-2,6-diphenyl-5-pyrimidinecarbonitrile | 4-...)
Show SMILES Nc1nc(nc(-c2ccccc2)c1C#N)-c1ccccc1
Show InChI InChI=1S/C17H12N4/c18-11-14-15(12-7-3-1-4-8-12)20-17(21-16(14)19)13-9-5-2-6-10-13/h1-10H,(H2,19,20,21)
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n/an/an/an/a 0.00117n/an/an/an/a



Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters

Curated by PubChem BioAssay


Assay Description
Assay Provider: Val Watts Assay Provider Affiliation: Purdue University Grant Title: Allosteric Modulators of D1 Receptors Grant Number: 1 X01 MH0776...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q2H41PVH
More data for this
Ligand-Target Pair
Dopamine D5 receptor


(Homo sapiens (Human))
BDBM40336
PNG
(6-Amino-4-isopropyl-3-thiophen-2-yl-2,4-dihydro-py...)
Show SMILES CC(C)C1C(C#N)C(=N)Oc2[nH]nc(-c3cccs3)c12
Show InChI InChI=1S/C14H14N4OS/c1-7(2)10-8(6-15)13(16)19-14-11(10)12(17-18-14)9-4-3-5-20-9/h3-5,7-8,10,16H,1-2H3,(H,17,18)
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n/an/an/an/a 0.00125n/an/an/an/a



Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters

Curated by PubChem BioAssay


Assay Description
Assay Provider: Val Watts Assay Provider Affiliation: Purdue University Grant Title: Allosteric Modulators of D1 Receptors Grant Number: 1 X01 MH0776...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q2MW2FJG
More data for this
Ligand-Target Pair
Dopamine D1 and D2 receptor


(Homo sapiens (Human))
BDBM48957
PNG
((5Z)-2-(1-azepanyl)-5-(7-bromo-5-methyl-2-oxo-1H-i...)
Show SMILES Cc1cc2\C(C(=O)Nc2c(Br)c1)=C1\SC(=NC1=O)N1CCCCCC1
Show InChI InChI=1S/C18H18BrN3O2S/c1-10-8-11-13(16(23)20-14(11)12(19)9-10)15-17(24)21-18(25-15)22-6-4-2-3-5-7-22/h8-9H,2-7H2,1H3,(H,20,23)/b15-13-
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n/an/an/an/a 0.00135n/an/an/an/a



Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters

Curated by PubChem BioAssay


Assay Description
Assay Provider: Val Watts Assay Provider Affiliation: Purdue University Grant Title: Allosteric Modulators of D1 Receptors Grant Number: 1 X01 MH0776...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q2H41PVH
More data for this
Ligand-Target Pair
Dopamine D1 and D2 receptor


(Homo sapiens (Human))
BDBM48971
PNG
(2-methylpropyl 6-(furan-2-yl)-3-methyl-4-oxidanyli...)
Show SMILES CC(C)COC(=O)c1[nH]c2CC(CC(=O)c2c1C)c1ccco1
Show InChI InChI=1S/C18H21NO4/c1-10(2)9-23-18(21)17-11(3)16-13(19-17)7-12(8-14(16)20)15-5-4-6-22-15/h4-6,10,12,19H,7-9H2,1-3H3
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n/an/an/an/a 0.00157n/an/an/an/a



Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters

Curated by PubChem BioAssay


Assay Description
Assay Provider: Val Watts Assay Provider Affiliation: Purdue University Grant Title: Allosteric Modulators of D1 Receptors Grant Number: 1 X01 MH0776...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q2H41PVH
More data for this
Ligand-Target Pair
Dopamine D1 and D2 receptor


(Homo sapiens (Human))
BDBM49031
PNG
(2-[5-(furan-2-yl)-4-oxidanylidene-3-phenyl-thieno[...)
Show SMILES NC(=O)CSc1nc2scc(-c3ccco3)c2c(=O)n1-c1ccccc1
Show InChI InChI=1S/C18H13N3O3S2/c19-14(22)10-26-18-20-16-15(12(9-25-16)13-7-4-8-24-13)17(23)21(18)11-5-2-1-3-6-11/h1-9H,10H2,(H2,19,22)
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n/an/an/an/a 0.00163n/an/an/an/a



Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters

Curated by PubChem BioAssay


Assay Description
Assay Provider: Val Watts Assay Provider Affiliation: Purdue University Grant Title: Allosteric Modulators of D1 Receptors Grant Number: 1 X01 MH0776...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q2H41PVH
More data for this
Ligand-Target Pair
Dopamine D5 receptor


(Homo sapiens (Human))
BDBM48904
PNG
(5-phenyl-[1,2,4]triazolo[4,3-c]quinazoline | MLS00...)
Show SMILES c1nnc2c3ccccc3nc(-c3ccccc3)n12
Show InChI InChI=1S/C15H10N4/c1-2-6-11(7-3-1)14-17-13-9-5-4-8-12(13)15-18-16-10-19(14)15/h1-10H
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n/an/an/an/a 0.00172n/an/an/an/a



Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters

Curated by PubChem BioAssay


Assay Description
Assay Provider: Val Watts Assay Provider Affiliation: Purdue University Grant Title: Allosteric Modulators of D1 Receptors Grant Number: 1 X01 MH0776...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q2MW2FJG
More data for this
Ligand-Target Pair
Dopamine D5 receptor


(Homo sapiens (Human))
BDBM48917
PNG
(1-phenyl-2-[[1-(phenylmethyl)-1,2,3,4-tetrazol-5-y...)
Show SMILES O=C(CSc1nnnn1Cc1ccccc1)c1ccccc1
Show InChI InChI=1S/C16H14N4OS/c21-15(14-9-5-2-6-10-14)12-22-16-17-18-19-20(16)11-13-7-3-1-4-8-13/h1-10H,11-12H2
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n/an/an/an/a 0.00173n/an/an/an/a



Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters

Curated by PubChem BioAssay


Assay Description
Assay Provider: Val Watts Assay Provider Affiliation: Purdue University Grant Title: Allosteric Modulators of D1 Receptors Grant Number: 1 X01 MH0776...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q2MW2FJG
More data for this
Ligand-Target Pair
Dopamine D1 and D2 receptor


(Homo sapiens (Human))
BDBM35425
PNG
(4-[5-(3-carbomethoxy-5-keto-2-methyl-1,4-dihydroin...)
Show SMILES COC(=O)C1C(C2=C(N=C1C)c1ccccc1C2=O)c1ccc(o1)-c1ccc(cc1)C(O)=O
Show InChI InChI=1S/C26H19NO6/c1-13-20(26(31)32-2)21(22-23(27-13)16-5-3-4-6-17(16)24(22)28)19-12-11-18(33-19)14-7-9-15(10-8-14)25(29)30/h3-12,20-21H,1-2H3,(H,29,30)
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n/an/an/an/a 0.00174n/an/an/an/a



Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters

Curated by PubChem BioAssay


Assay Description
Assay Provider: Val Watts Assay Provider Affiliation: Purdue University Grant Title: Allosteric Modulators of D1 Receptors Grant Number: 1 X01 MH0776...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q2H41PVH
More data for this
Ligand-Target Pair
Dopamine D5 receptor


(Homo sapiens (Human))
BDBM48908
PNG
(2-hydroxy-4-keto-1-propyl-N-(4-pyridylmethyl)quino...)
Show SMILES CCCn1c2ccccc2c(O)c(C(=O)NCc2ccncc2)c1=O
Show InChI InChI=1S/C19H19N3O3/c1-2-11-22-15-6-4-3-5-14(15)17(23)16(19(22)25)18(24)21-12-13-7-9-20-10-8-13/h3-10,23H,2,11-12H2,1H3,(H,21,24)
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n/an/an/an/a 0.00174n/an/an/an/a



Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters

Curated by PubChem BioAssay


Assay Description
Assay Provider: Val Watts Assay Provider Affiliation: Purdue University Grant Title: Allosteric Modulators of D1 Receptors Grant Number: 1 X01 MH0776...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q2MW2FJG
More data for this
Ligand-Target Pair
Dopamine D5 receptor


(Homo sapiens (Human))
BDBM48971
PNG
(2-methylpropyl 6-(furan-2-yl)-3-methyl-4-oxidanyli...)
Show SMILES CC(C)COC(=O)c1[nH]c2CC(CC(=O)c2c1C)c1ccco1
Show InChI InChI=1S/C18H21NO4/c1-10(2)9-23-18(21)17-11(3)16-13(19-17)7-12(8-14(16)20)15-5-4-6-22-15/h4-6,10,12,19H,7-9H2,1-3H3
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n/an/an/an/a 0.00175n/an/an/an/a



Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters

Curated by PubChem BioAssay


Assay Description
Assay Provider: Val Watts Assay Provider Affiliation: Purdue University Grant Title: Allosteric Modulators of D1 Receptors Grant Number: 1 X01 MH0776...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q2MW2FJG
More data for this
Ligand-Target Pair
Dopamine D1 and D2 receptor


(Homo sapiens (Human))
BDBM48941
PNG
(4-hydroxy-6-(4-isopropylphenyl)-2-piperidin-1-ylpy...)
Show SMILES CC(C)c1ccc(cc1)-c1nc([nH]c(=O)c1C#N)N1CCCCC1
Show InChI InChI=1S/C19H22N4O/c1-13(2)14-6-8-15(9-7-14)17-16(12-20)18(24)22-19(21-17)23-10-4-3-5-11-23/h6-9,13H,3-5,10-11H2,1-2H3,(H,21,22,24)
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n/an/an/an/a 0.00175n/an/an/an/a



Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters

Curated by PubChem BioAssay


Assay Description
Assay Provider: Val Watts Assay Provider Affiliation: Purdue University Grant Title: Allosteric Modulators of D1 Receptors Grant Number: 1 X01 MH0776...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q2H41PVH
More data for this
Ligand-Target Pair
Dopamine D5 receptor


(Homo sapiens (Human))
BDBM43357
PNG
(2-(2-chlorophenyl)-5-(dimethylamino)-1,3-oxazole-4...)
Show SMILES CN(C)c1oc(nc1C#N)-c1ccccc1Cl
Show InChI InChI=1S/C12H10ClN3O/c1-16(2)12-10(7-14)15-11(17-12)8-5-3-4-6-9(8)13/h3-6H,1-2H3
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n/an/an/an/a 0.00186n/an/an/an/a



Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters

Curated by PubChem BioAssay


Assay Description
Assay Provider: Val Watts Assay Provider Affiliation: Purdue University Grant Title: Allosteric Modulators of D1 Receptors Grant Number: 1 X01 MH0776...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q2MW2FJG
More data for this
Ligand-Target Pair
Dopamine D5 receptor


(Homo sapiens (Human))
BDBM41448
PNG
(2,2-diketo-6-phenyl-3,4-dihydrothiazolo[2,3-c][1,2...)
Show SMILES CCOC(=O)C1=C(N2C=CS(=O)(=O)NC2S1)c1ccccc1
Show InChI InChI=1S/C14H14N2O4S2/c1-2-20-13(17)12-11(10-6-4-3-5-7-10)16-8-9-22(18,19)15-14(16)21-12/h3-9,14-15H,2H2,1H3
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n/an/an/an/a 0.00189n/an/an/an/a



Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters

Curated by PubChem BioAssay


Assay Description
Assay Provider: Val Watts Assay Provider Affiliation: Purdue University Grant Title: Allosteric Modulators of D1 Receptors Grant Number: 1 X01 MH0776...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q2MW2FJG
More data for this
Ligand-Target Pair
Dopamine D5 receptor


(Homo sapiens (Human))
BDBM37376
PNG
(MLS000042779 | N-[1,3-benzothiazol-2-ylimino-(1-ox...)
Show SMILES CCC(=O)NC(NC(=O)CC)=Nc1nc2ccccc2s1
Show InChI InChI=1S/C14H16N4O2S/c1-3-11(19)16-13(17-12(20)4-2)18-14-15-9-7-5-6-8-10(9)21-14/h5-8H,3-4H2,1-2H3,(H2,15,16,17,18,19,20)
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n/an/an/an/a 0.00190n/an/an/an/a



Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters

Curated by PubChem BioAssay


Assay Description
Assay Provider: Val Watts Assay Provider Affiliation: Purdue University Grant Title: Allosteric Modulators of D1 Receptors Grant Number: 1 X01 MH0776...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q2MW2FJG
More data for this
Ligand-Target Pair
Dopamine D5 receptor


(Homo sapiens (Human))
BDBM48976
PNG
(MLS000102793 | N-(3-thiazolo[5,4-b]pyridin-2-ylphe...)
Show SMILES O=S(=O)(Nc1cccc(c1)-c1nc2cccnc2s1)c1ccc2OCCOc2c1
Show InChI InChI=1S/C20H15N3O4S2/c24-29(25,15-6-7-17-18(12-15)27-10-9-26-17)23-14-4-1-3-13(11-14)19-22-16-5-2-8-21-20(16)28-19/h1-8,11-12,23H,9-10H2
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n/an/an/an/a 0.00195n/an/an/an/a



Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters

Curated by PubChem BioAssay


Assay Description
Assay Provider: Val Watts Assay Provider Affiliation: Purdue University Grant Title: Allosteric Modulators of D1 Receptors Grant Number: 1 X01 MH0776...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q2MW2FJG
More data for this
Ligand-Target Pair
Dopamine D1 and D2 receptor


(Homo sapiens (Human))
BDBM32031
PNG
(2-[(2,5-dimethoxybenzylidene)amino]-4,5-bis(2-fury...)
Show SMILES COc1ccc(OC)c(C=Nc2oc(-c3ccco3)c(-c3ccco3)c2C#N)c1
Show InChI InChI=1S/C22H16N2O5/c1-25-15-7-8-17(26-2)14(11-15)13-24-22-16(12-23)20(18-5-3-9-27-18)21(29-22)19-6-4-10-28-19/h3-11,13H,1-2H3
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n/an/an/an/a 0.00197n/an/an/an/a



Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters

Curated by PubChem BioAssay


Assay Description
Assay Provider: Val Watts Assay Provider Affiliation: Purdue University Grant Title: Allosteric Modulators of D1 Receptors Grant Number: 1 X01 MH0776...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q2H41PVH
More data for this
Ligand-Target Pair
Dopamine D1 and D2 receptor


(Homo sapiens (Human))
BDBM48966
PNG
(1-(3-amino-7-methoxy-1-pyrazolo[3,4-b]quinolinyl)-...)
Show SMILES COc1ccc2cc3c(N)nn(C(=O)Cc4ccccc4OC)c3nc2c1
Show InChI InChI=1S/C20H18N4O3/c1-26-14-8-7-12-9-15-19(21)23-24(20(15)22-16(12)11-14)18(25)10-13-5-3-4-6-17(13)27-2/h3-9,11H,10H2,1-2H3,(H2,21,23)
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n/an/an/an/a 0.00201n/an/an/an/a



Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters

Curated by PubChem BioAssay


Assay Description
Assay Provider: Val Watts Assay Provider Affiliation: Purdue University Grant Title: Allosteric Modulators of D1 Receptors Grant Number: 1 X01 MH0776...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q2H41PVH
More data for this
Ligand-Target Pair
Dopamine D5 receptor


(Homo sapiens (Human))
BDBM48925
PNG
(2-amino-4-(2-furanyl)-5-methyl-6-phenyl-3-pyridine...)
Show SMILES Cc1c(nc(N)c(C#N)c1-c1ccco1)-c1ccccc1
Show InChI InChI=1S/C17H13N3O/c1-11-15(14-8-5-9-21-14)13(10-18)17(19)20-16(11)12-6-3-2-4-7-12/h2-9H,1H3,(H2,19,20)
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n/an/an/an/a 0.00201n/an/an/an/a



Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters

Curated by PubChem BioAssay


Assay Description
Assay Provider: Val Watts Assay Provider Affiliation: Purdue University Grant Title: Allosteric Modulators of D1 Receptors Grant Number: 1 X01 MH0776...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q2MW2FJG
More data for this
Ligand-Target Pair
Dopamine D1 and D2 receptor


(Homo sapiens (Human))
BDBM48950
PNG
(1-butyl-5-keto-2-nicotinoylimino-dipyrido[1,2-d:3'...)
Show SMILES CCCCn1c2nc3ccccn3c(=O)c2cc(C(=O)OCC)\c1=N/C(=O)c1cccnc1
Show InChI InChI=1S/C24H23N5O4/c1-3-5-12-29-20-17(23(31)28-13-7-6-10-19(28)26-20)14-18(24(32)33-4-2)21(29)27-22(30)16-9-8-11-25-15-16/h6-11,13-15H,3-5,12H2,1-2H3/b27-21+
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n/an/an/an/a 0.00202n/an/an/an/a



Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters

Curated by PubChem BioAssay


Assay Description
Assay Provider: Val Watts Assay Provider Affiliation: Purdue University Grant Title: Allosteric Modulators of D1 Receptors Grant Number: 1 X01 MH0776...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q2H41PVH
More data for this
Ligand-Target Pair
Dopamine D5 receptor


(Homo sapiens (Human))
BDBM48970
PNG
(MLS000116276 | N-butyl-5-(3,4-dimethoxyphenyl)-1,2...)
Show SMILES CCCCNC(=O)c1cc(on1)-c1ccc(OC)c(OC)c1
Show InChI InChI=1S/C16H20N2O4/c1-4-5-8-17-16(19)12-10-14(22-18-12)11-6-7-13(20-2)15(9-11)21-3/h6-7,9-10H,4-5,8H2,1-3H3,(H,17,19)
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n/an/an/an/a 0.00207n/an/an/an/a



Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters

Curated by PubChem BioAssay


Assay Description
Assay Provider: Val Watts Assay Provider Affiliation: Purdue University Grant Title: Allosteric Modulators of D1 Receptors Grant Number: 1 X01 MH0776...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q2MW2FJG
More data for this
Ligand-Target Pair
Dopamine D5 receptor


(Homo sapiens (Human))
BDBM48979
PNG
((3,4,5-triacetyloxy-6-phenyl-oxan-2-yl)methyl etha...)
Show SMILES CC(=O)OCC1OC(C(OC(C)=O)C(OC(C)=O)C1OC(C)=O)c1ccccc1
Show InChI InChI=1S/C20H24O9/c1-11(21)25-10-16-18(26-12(2)22)20(28-14(4)24)19(27-13(3)23)17(29-16)15-8-6-5-7-9-15/h5-9,16-20H,10H2,1-4H3
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n/an/an/an/a 0.00210n/an/an/an/a



Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters

Curated by PubChem BioAssay


Assay Description
Assay Provider: Val Watts Assay Provider Affiliation: Purdue University Grant Title: Allosteric Modulators of D1 Receptors Grant Number: 1 X01 MH0776...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q2MW2FJG
More data for this
Ligand-Target Pair
Dopamine D5 receptor


(Homo sapiens (Human))
BDBM48919
PNG
(2,6-bis(azanyl)-4-(4-ethoxy-3-methoxy-phenyl)-4H-t...)
Show SMILES CCOc1ccc(cc1OC)C1C(C#N)C(=N)SC(=N)C1C#N
Show InChI InChI=1S/C16H16N4O2S/c1-3-22-12-5-4-9(6-13(12)21-2)14-10(7-17)15(19)23-16(20)11(14)8-18/h4-6,10-11,14,19-20H,3H2,1-2H3
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n/an/an/an/a 0.00212n/an/an/an/a



Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters

Curated by PubChem BioAssay


Assay Description
Assay Provider: Val Watts Assay Provider Affiliation: Purdue University Grant Title: Allosteric Modulators of D1 Receptors Grant Number: 1 X01 MH0776...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q2MW2FJG
More data for this
Ligand-Target Pair
Dopamine D1 and D2 receptor


(Homo sapiens (Human))
BDBM49027
PNG
(3-methyl-5-[[1-oxo-2-(1,3,4-thiadiazol-2-ylthio)et...)
Show SMILES CCOC(=O)c1sc(NC(=O)CSc2nncs2)c(C(=O)OCC)c1C
Show InChI InChI=1S/C15H17N3O5S3/c1-4-22-13(20)10-8(3)11(14(21)23-5-2)26-12(10)17-9(19)6-24-15-18-16-7-25-15/h7H,4-6H2,1-3H3,(H,17,19)
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n/an/an/an/a 0.00223n/an/an/an/a



Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters

Curated by PubChem BioAssay


Assay Description
Assay Provider: Val Watts Assay Provider Affiliation: Purdue University Grant Title: Allosteric Modulators of D1 Receptors Grant Number: 1 X01 MH0776...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q2H41PVH
More data for this
Ligand-Target Pair
Dopamine D1 and D2 receptor


(Homo sapiens (Human))
BDBM49040
PNG
(7-(4-carbomethoxyphenyl)-5-methyl-2-(methylthio)-1...)
Show SMILES CCOC(=O)C1C(c2ccc(cc2)C(=O)OC)n2nc(SC)nc2N=C1C
Show InChI InChI=1S/C18H20N4O4S/c1-5-26-16(24)13-10(2)19-17-20-18(27-4)21-22(17)14(13)11-6-8-12(9-7-11)15(23)25-3/h6-9,13-14H,5H2,1-4H3
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n/an/an/an/a 0.00231n/an/an/an/a



Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters

Curated by PubChem BioAssay


Assay Description
Assay Provider: Val Watts Assay Provider Affiliation: Purdue University Grant Title: Allosteric Modulators of D1 Receptors Grant Number: 1 X01 MH0776...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q2H41PVH
More data for this
Ligand-Target Pair
Dopamine D1 and D2 receptor


(Homo sapiens (Human))
BDBM49001
PNG
(5-acetyl-2-methyl-6-(methylamino)-4-phenyl-3-pyrid...)
Show SMILES CNc1nc(C)c(C#N)c(-c2ccccc2)c1C(C)=O
Show InChI InChI=1S/C16H15N3O/c1-10-13(9-17)15(12-7-5-4-6-8-12)14(11(2)20)16(18-3)19-10/h4-8H,1-3H3,(H,18,19)
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n/an/an/an/a 0.00233n/an/an/an/a



Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters

Curated by PubChem BioAssay


Assay Description
Assay Provider: Val Watts Assay Provider Affiliation: Purdue University Grant Title: Allosteric Modulators of D1 Receptors Grant Number: 1 X01 MH0776...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q2H41PVH
More data for this
Ligand-Target Pair
Dopamine D1 and D2 receptor


(Homo sapiens (Human))
BDBM37477
PNG
(1-[6-(4-ethoxy-3-methoxy-phenyl)-3-(methylthio)-6H...)
Show SMILES CCOc1ccc(cc1OC)C1Oc2nc(SC)nnc2-c2ccccc2N1C(C)=O
Show InChI InChI=1S/C22H22N4O4S/c1-5-29-17-11-10-14(12-18(17)28-3)21-26(13(2)27)16-9-7-6-8-15(16)19-20(30-21)23-22(31-4)25-24-19/h6-12,21H,5H2,1-4H3
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n/an/an/an/a 0.00238n/an/an/an/a



Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters

Curated by PubChem BioAssay


Assay Description
Assay Provider: Val Watts Assay Provider Affiliation: Purdue University Grant Title: Allosteric Modulators of D1 Receptors Grant Number: 1 X01 MH0776...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q2H41PVH
More data for this
Ligand-Target Pair
Dopamine D1 and D2 receptor


(Homo sapiens (Human))
BDBM49033
PNG
(1-(5-bromanylpyridin-2-yl)-3-butyl-urea | 1-(5-bro...)
Show SMILES CCCCNC(=O)Nc1ccc(Br)cn1
Show InChI InChI=1S/C10H14BrN3O/c1-2-3-6-12-10(15)14-9-5-4-8(11)7-13-9/h4-5,7H,2-3,6H2,1H3,(H2,12,13,14,15)
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n/an/an/an/a 0.00243n/an/an/an/a



Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters

Curated by PubChem BioAssay


Assay Description
Assay Provider: Val Watts Assay Provider Affiliation: Purdue University Grant Title: Allosteric Modulators of D1 Receptors Grant Number: 1 X01 MH0776...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q2H41PVH
More data for this
Ligand-Target Pair
Dopamine D1 and D2 receptor


(Homo sapiens (Human))
BDBM40513
PNG
(5-[[[1-(4-fluorophenyl)-4-keto-2H-pyrazolo[3,4-d]p...)
Show SMILES COC(=O)c1ccc(CSc2nc3n(ncc3c(=O)[nH]2)-c2ccc(F)cc2)o1
Show InChI InChI=1S/C18H13FN4O4S/c1-26-17(25)14-7-6-12(27-14)9-28-18-21-15-13(16(24)22-18)8-20-23(15)11-4-2-10(19)3-5-11/h2-8H,9H2,1H3,(H,21,22,24)
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n/an/an/an/a 0.00249n/an/an/an/a



Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters

Curated by PubChem BioAssay


Assay Description
Assay Provider: Val Watts Assay Provider Affiliation: Purdue University Grant Title: Allosteric Modulators of D1 Receptors Grant Number: 1 X01 MH0776...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q2H41PVH
More data for this
Ligand-Target Pair
Dopamine D1 and D2 receptor


(Homo sapiens (Human))
BDBM49096
PNG
(6-(cyclohexylamino)-8-(2-furanyl)-3,3-dimethyl-1,4...)
Show SMILES CC1(C)Cc2c(CO1)c(nc(NC1CCCCC1)c2C#N)-c1ccco1
Show InChI InChI=1S/C21H25N3O2/c1-21(2)11-15-16(12-22)20(23-14-7-4-3-5-8-14)24-19(17(15)13-26-21)18-9-6-10-25-18/h6,9-10,14H,3-5,7-8,11,13H2,1-2H3,(H,23,24)
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n/an/an/an/a 0.00260n/an/an/an/a



Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters

Curated by PubChem BioAssay


Assay Description
Assay Provider: Val Watts Assay Provider Affiliation: Purdue University Grant Title: Allosteric Modulators of D1 Receptors Grant Number: 1 X01 MH0776...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q2H41PVH
More data for this
Ligand-Target Pair
Dopamine D1 and D2 receptor


(Homo sapiens (Human))
BDBM49051
PNG
(1-[1-(3-chlorophenyl)-4-(2-furoyl)-1H-pyrazol-3-yl...)
Show SMILES CC(=O)c1nn(cc1C(=O)c1ccco1)-c1cccc(Cl)c1
Show InChI InChI=1S/C16H11ClN2O3/c1-10(20)15-13(16(21)14-6-3-7-22-14)9-19(18-15)12-5-2-4-11(17)8-12/h2-9H,1H3
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n/an/an/an/a 0.00279n/an/an/an/a



Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters

Curated by PubChem BioAssay


Assay Description
Assay Provider: Val Watts Assay Provider Affiliation: Purdue University Grant Title: Allosteric Modulators of D1 Receptors Grant Number: 1 X01 MH0776...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q2H41PVH
More data for this
Ligand-Target Pair
Dopamine receptor


(Homo sapiens (Human))
BDBM50341508
PNG
((S)-N-(4-(4-Phenylbenzoylamino)butyl)-N-propyl-5-a...)
Show SMILES CCCN(CCCCNC(=O)c1ccc(cc1)-c1ccccc1)[C@H]1CCn2nccc2C1
Show InChI InChI=1S/C27H34N4O/c1-2-18-30(25-15-20-31-26(21-25)14-17-29-31)19-7-6-16-28-27(32)24-12-10-23(11-13-24)22-8-4-3-5-9-22/h3-5,8-14,17,25H,2,6-7,15-16,18-21H2,1H3,(H,28,32)/t25-/m0/s1
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n/an/an/an/a 0.00280n/an/an/an/a



Friedrich Alexander University

Curated by ChEMBL


Assay Description
Agonist activity at human dopamine D3 receptor expressed in CHO cells assessed as induction of [3H]thymidine incorporation after 2 hrs


J Med Chem 54: 2477-91 (2011)


Article DOI: 10.1021/jm101639t
BindingDB Entry DOI: 10.7270/Q2V1253W
More data for this
Ligand-Target Pair
Dopamine D1 and D2 receptor


(Homo sapiens (Human))
BDBM47104
PNG
(MLS000092489 | N-(1,3-benzodioxol-5-yl)-2-(1-ethyl...)
Show SMILES CCn1c2ccccc2c(SCC(=O)Nc2ccc3OCOc3c2)cc1=O
Show InChI InChI=1S/C20H18N2O4S/c1-2-22-15-6-4-3-5-14(15)18(10-20(22)24)27-11-19(23)21-13-7-8-16-17(9-13)26-12-25-16/h3-10H,2,11-12H2,1H3,(H,21,23)
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n/an/an/an/a 0.00289n/an/an/an/a



Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters

Curated by PubChem BioAssay


Assay Description
Assay Provider: Val Watts Assay Provider Affiliation: Purdue University Grant Title: Allosteric Modulators of D1 Receptors Grant Number: 1 X01 MH0776...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q2H41PVH
More data for this
Ligand-Target Pair
Dopamine D5 receptor


(Homo sapiens (Human))
BDBM48905
PNG
(2-amino-4-(3-thienyl)thiophene-3-carboxylic acid e...)
Show SMILES CCOC(=O)c1c(N)scc1-c1ccsc1
Show InChI InChI=1S/C11H11NO2S2/c1-2-14-11(13)9-8(6-16-10(9)12)7-3-4-15-5-7/h3-6H,2,12H2,1H3
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n/an/an/an/a 0.00302n/an/an/an/a



Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters

Curated by PubChem BioAssay


Assay Description
Assay Provider: Val Watts Assay Provider Affiliation: Purdue University Grant Title: Allosteric Modulators of D1 Receptors Grant Number: 1 X01 MH0776...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q2MW2FJG
More data for this
Ligand-Target Pair
Dopamine D1 and D2 receptor


(Homo sapiens (Human))
BDBM49059
PNG
(2-[(2-isopropyl-3-keto-2H-imidazo[1,2-c]quinazolin...)
Show SMILES CC(C)C1N=C2N(C1=O)C(SCC#N)=Nc1ccccc21
Show InChI InChI=1S/C15H14N4OS/c1-9(2)12-14(20)19-13(18-12)10-5-3-4-6-11(10)17-15(19)21-8-7-16/h3-6,9,12H,8H2,1-2H3
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n/an/an/an/a 0.00314n/an/an/an/a



Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters

Curated by PubChem BioAssay


Assay Description
Assay Provider: Val Watts Assay Provider Affiliation: Purdue University Grant Title: Allosteric Modulators of D1 Receptors Grant Number: 1 X01 MH0776...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q2H41PVH
More data for this
Ligand-Target Pair
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