Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Epidermal growth factor receptor(L858R, T790M) (Homo sapiens (Human)) | BDBM202369![]() (US10081606, Compound I-1 | US9238629, I-1 | US9765...) | PDB MMDB KEGG B.MOAD DrugBank GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 55 | n/a | n/a | n/a | n/a |
Celgene Avilomics Research, Inc. US Patent | Assay Description To assess phosphor-EGFR signaling, blots were probed with rabbit anti-Phospho-EGFR (Y1068) and mouse total anti-EGFR antibodies. Phospho-EGFR signal ... | US Patent US9238629 (2016) BindingDB Entry DOI: 10.7270/Q2P849Q7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epidermal growth factor receptor(L858R, T790M) (Homo sapiens (Human)) | BDBM202370![]() (US10081606, Compound I-2 | US9238629, I-2 | US9765...) | PDB MMDB KEGG B.MOAD DrugBank GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 55 | n/a | n/a | n/a | n/a |
Celgene Avilomics Research, Inc. US Patent | Assay Description To assess phosphor-EGFR signaling, blots were probed with rabbit anti-Phospho-EGFR (Y1068) and mouse total anti-EGFR antibodies. Phospho-EGFR signal ... | US Patent US9238629 (2016) BindingDB Entry DOI: 10.7270/Q2P849Q7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epidermal growth factor receptor(L858R, T790M) (Homo sapiens (Human)) | BDBM202379![]() (US10081606, Compound I-11 | US9238629, I-11 | US97...) | PDB MMDB KEGG B.MOAD DrugBank GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 55 | n/a | n/a | n/a | n/a |
Celgene Avilomics Research, Inc. US Patent | Assay Description To assess phosphor-EGFR signaling, blots were probed with rabbit anti-Phospho-EGFR (Y1068) and mouse total anti-EGFR antibodies. Phospho-EGFR signal ... | US Patent US9238629 (2016) BindingDB Entry DOI: 10.7270/Q2P849Q7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epidermal growth factor receptor(L858R, T790M) (Homo sapiens (Human)) | BDBM202378![]() (US10081606, Compound I-10 | US9238629, I-10 | US97...) | PDB MMDB KEGG B.MOAD DrugBank GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 55 | n/a | n/a | n/a | n/a |
Celgene Avilomics Research, Inc. US Patent | Assay Description To assess phosphor-EGFR signaling, blots were probed with rabbit anti-Phospho-EGFR (Y1068) and mouse total anti-EGFR antibodies. Phospho-EGFR signal ... | US Patent US9238629 (2016) BindingDB Entry DOI: 10.7270/Q2P849Q7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epidermal growth factor receptor(L858R, T790M) (Homo sapiens (Human)) | BDBM202377![]() (US10081606, Compound I-9 | US9238629, I-9 | US9765...) | PDB MMDB KEGG B.MOAD DrugBank GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 55 | n/a | n/a | n/a | n/a |
Celgene Avilomics Research, Inc. US Patent | Assay Description To assess phosphor-EGFR signaling, blots were probed with rabbit anti-Phospho-EGFR (Y1068) and mouse total anti-EGFR antibodies. Phospho-EGFR signal ... | US Patent US9238629 (2016) BindingDB Entry DOI: 10.7270/Q2P849Q7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epidermal growth factor receptor(L858R, T790M) (Homo sapiens (Human)) | BDBM202375![]() (US10081606, Compound I-7 | US9238629, I-7 | US9765...) | PDB MMDB KEGG B.MOAD DrugBank GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 55 | n/a | n/a | n/a | n/a |
Celgene Avilomics Research, Inc. US Patent | Assay Description To assess phosphor-EGFR signaling, blots were probed with rabbit anti-Phospho-EGFR (Y1068) and mouse total anti-EGFR antibodies. Phospho-EGFR signal ... | US Patent US9238629 (2016) BindingDB Entry DOI: 10.7270/Q2P849Q7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epidermal growth factor receptor(L858R, T790M) (Homo sapiens (Human)) | BDBM202374![]() (US10081606, Compound I-6 | US9238629, I-14 | US923...) | PDB MMDB KEGG B.MOAD DrugBank GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 55 | n/a | n/a | n/a | n/a |
Celgene Avilomics Research, Inc. US Patent | Assay Description To assess phosphor-EGFR signaling, blots were probed with rabbit anti-Phospho-EGFR (Y1068) and mouse total anti-EGFR antibodies. Phospho-EGFR signal ... | US Patent US9238629 (2016) BindingDB Entry DOI: 10.7270/Q2P849Q7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epidermal growth factor receptor(L858R, T790M) (Homo sapiens (Human)) | BDBM202373![]() (US10081606, Compound I-5 | US9238629, I-5 | US9765...) | PDB MMDB KEGG B.MOAD DrugBank GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 55 | n/a | n/a | n/a | n/a |
Celgene Avilomics Research, Inc. US Patent | Assay Description To assess phosphor-EGFR signaling, blots were probed with rabbit anti-Phospho-EGFR (Y1068) and mouse total anti-EGFR antibodies. Phospho-EGFR signal ... | US Patent US9238629 (2016) BindingDB Entry DOI: 10.7270/Q2P849Q7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epidermal growth factor receptor(L858R, T790M) (Homo sapiens (Human)) | BDBM202371![]() (US10081606, Compound I-3 | US9238629, I-3 | US9765...) | PDB MMDB KEGG B.MOAD DrugBank GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 55 | n/a | n/a | n/a | n/a |
Celgene Avilomics Research, Inc. US Patent | Assay Description To assess phosphor-EGFR signaling, blots were probed with rabbit anti-Phospho-EGFR (Y1068) and mouse total anti-EGFR antibodies. Phospho-EGFR signal ... | US Patent US9238629 (2016) BindingDB Entry DOI: 10.7270/Q2P849Q7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epidermal growth factor receptor(L858R, T790M) (Homo sapiens (Human)) | BDBM202383![]() (US10081606, Compound I-15 | US9238629, I-15 | US97...) | PDB MMDB KEGG B.MOAD DrugBank GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 300 | n/a | n/a | n/a | n/a |
Celgene Avilomics Research, Inc. US Patent | Assay Description To assess phosphor-EGFR signaling, blots were probed with rabbit anti-Phospho-EGFR (Y1068) and mouse total anti-EGFR antibodies. Phospho-EGFR signal ... | US Patent US9238629 (2016) BindingDB Entry DOI: 10.7270/Q2P849Q7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epidermal growth factor receptor(L858R, T790M) (Homo sapiens (Human)) | BDBM202390![]() (US10081606, Compound I-22 | US9238629, I-22 | US97...) | PDB MMDB KEGG B.MOAD DrugBank GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 300 | n/a | n/a | n/a | n/a |
Celgene Avilomics Research, Inc. US Patent | Assay Description To assess phosphor-EGFR signaling, blots were probed with rabbit anti-Phospho-EGFR (Y1068) and mouse total anti-EGFR antibodies. Phospho-EGFR signal ... | US Patent US9238629 (2016) BindingDB Entry DOI: 10.7270/Q2P849Q7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epidermal growth factor receptor(L858R, T790M) (Homo sapiens (Human)) | BDBM202388![]() (US10081606, Compound I-20 | US9238629, I-20 | US97...) | PDB MMDB KEGG B.MOAD DrugBank GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 300 | n/a | n/a | n/a | n/a |
Celgene Avilomics Research, Inc. US Patent | Assay Description To assess phosphor-EGFR signaling, blots were probed with rabbit anti-Phospho-EGFR (Y1068) and mouse total anti-EGFR antibodies. Phospho-EGFR signal ... | US Patent US9238629 (2016) BindingDB Entry DOI: 10.7270/Q2P849Q7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epidermal growth factor receptor(L858R, T790M) (Homo sapiens (Human)) | BDBM202376![]() (US10081606, Compound I-8 | US9238629, I-8 | US9765...) | PDB MMDB KEGG B.MOAD DrugBank GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 300 | n/a | n/a | n/a | n/a |
Celgene Avilomics Research, Inc. US Patent | Assay Description To assess phosphor-EGFR signaling, blots were probed with rabbit anti-Phospho-EGFR (Y1068) and mouse total anti-EGFR antibodies. Phospho-EGFR signal ... | US Patent US9238629 (2016) BindingDB Entry DOI: 10.7270/Q2P849Q7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epidermal growth factor receptor(L858R, T790M) (Homo sapiens (Human)) | BDBM202384![]() (US10081606, Compound I-16 | US9238629, I-16 | US97...) | PDB MMDB KEGG B.MOAD DrugBank GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 300 | n/a | n/a | n/a | n/a |
Celgene Avilomics Research, Inc. US Patent | Assay Description To assess phosphor-EGFR signaling, blots were probed with rabbit anti-Phospho-EGFR (Y1068) and mouse total anti-EGFR antibodies. Phospho-EGFR signal ... | US Patent US9238629 (2016) BindingDB Entry DOI: 10.7270/Q2P849Q7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epidermal growth factor receptor(L858R, T790M) (Homo sapiens (Human)) | BDBM202381![]() (US10081606, Compound I-13 | US9238629, I-13 | US97...) | PDB MMDB KEGG B.MOAD DrugBank GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 300 | n/a | n/a | n/a | n/a |
Celgene Avilomics Research, Inc. US Patent | Assay Description To assess phosphor-EGFR signaling, blots were probed with rabbit anti-Phospho-EGFR (Y1068) and mouse total anti-EGFR antibodies. Phospho-EGFR signal ... | US Patent US9238629 (2016) BindingDB Entry DOI: 10.7270/Q2P849Q7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epidermal growth factor receptor(L858R, T790M) (Homo sapiens (Human)) | BDBM202372![]() (US10081606, Compound I-4 | US9238629, I-4 | US9765...) | PDB MMDB KEGG B.MOAD DrugBank GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 300 | n/a | n/a | n/a | n/a |
Celgene Avilomics Research, Inc. US Patent | Assay Description To assess phosphor-EGFR signaling, blots were probed with rabbit anti-Phospho-EGFR (Y1068) and mouse total anti-EGFR antibodies. Phospho-EGFR signal ... | US Patent US9238629 (2016) BindingDB Entry DOI: 10.7270/Q2P849Q7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epidermal growth factor receptor(L858R, T790M) (Homo sapiens (Human)) | BDBM202389![]() (US10081606, Compound I-21 | US9238629, I-21 | US97...) | PDB MMDB KEGG B.MOAD DrugBank GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 800 | n/a | n/a | n/a | n/a |
Celgene Avilomics Research, Inc. US Patent | Assay Description To assess phosphor-EGFR signaling, blots were probed with rabbit anti-Phospho-EGFR (Y1068) and mouse total anti-EGFR antibodies. Phospho-EGFR signal ... | US Patent US9238629 (2016) BindingDB Entry DOI: 10.7270/Q2P849Q7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epidermal growth factor receptor(L858R, T790M) (Homo sapiens (Human)) | BDBM202391![]() (US10081606, Compound I-23 | US9238629, I-23 | US97...) | PDB MMDB KEGG B.MOAD DrugBank GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a |
Celgene Avilomics Research, Inc. US Patent | Assay Description To assess phosphor-EGFR signaling, blots were probed with rabbit anti-Phospho-EGFR (Y1068) and mouse total anti-EGFR antibodies. Phospho-EGFR signal ... | US Patent US9238629 (2016) BindingDB Entry DOI: 10.7270/Q2P849Q7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epidermal growth factor receptor(L858R, T790M) (Homo sapiens (Human)) | BDBM173450![]() (US9096601, 8-24) | PDB MMDB KEGG B.MOAD DrugBank GoogleScholar | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 522 | n/a | n/a | n/a | n/a | n/a | n/a |
CSPC Zhongqi Pharmaceutical Technology (Shijiazhuang) Co., Ltd. US Patent | Assay Description The object of this assay was to test the inventive compounds for the kinase inhibitory activity in vitro. In this assay, an isotopic labeling method ... | US Patent US9096601 (2015) BindingDB Entry DOI: 10.7270/Q2NS0SNG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epidermal growth factor receptor(L858R, T790M) (Homo sapiens (Human)) | BDBM173451![]() (US9096601, 8-25) | PDB MMDB KEGG B.MOAD DrugBank GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 458 | n/a | n/a | n/a | n/a | n/a | n/a |
CSPC Zhongqi Pharmaceutical Technology (Shijiazhuang) Co., Ltd. US Patent | Assay Description The object of this assay was to test the inventive compounds for the kinase inhibitory activity in vitro. In this assay, an isotopic labeling method ... | US Patent US9096601 (2015) BindingDB Entry DOI: 10.7270/Q2NS0SNG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epidermal growth factor receptor(L858R, T790M) (Homo sapiens (Human)) | BDBM50399676![]() (CHEMBL2178352 | US9096601, 8-26) | PDB MMDB KEGG B.MOAD DrugBank GoogleScholar | CHEMBL PC cid PC sid PDB UniChem Similars | PDB US Patent | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
CSPC Zhongqi Pharmaceutical Technology (Shijiazhuang) Co., Ltd. US Patent | Assay Description The object of this assay was to test the inventive compounds for the kinase inhibitory activity in vitro. In this assay, an isotopic labeling method ... | US Patent US9096601 (2015) BindingDB Entry DOI: 10.7270/Q2NS0SNG | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
Epidermal growth factor receptor(L858R, T790M) (Homo sapiens (Human)) | BDBM173452![]() (US9096601, 8-27) | PDB MMDB KEGG B.MOAD DrugBank GoogleScholar | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 54 | n/a | n/a | n/a | n/a | n/a | n/a |
CSPC Zhongqi Pharmaceutical Technology (Shijiazhuang) Co., Ltd. US Patent | Assay Description The object of this assay was to test the inventive compounds for the kinase inhibitory activity in vitro. In this assay, an isotopic labeling method ... | US Patent US9096601 (2015) BindingDB Entry DOI: 10.7270/Q2NS0SNG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epidermal growth factor receptor(L858R, T790M) (Homo sapiens (Human)) | BDBM173454![]() (US9096601, 8-29) | PDB MMDB KEGG B.MOAD DrugBank GoogleScholar | Purchase PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 64 | n/a | n/a | n/a | n/a | n/a | n/a |
CSPC Zhongqi Pharmaceutical Technology (Shijiazhuang) Co., Ltd. US Patent | Assay Description The object of this assay was to test the inventive compounds for the kinase inhibitory activity in vitro. In this assay, an isotopic labeling method ... | US Patent US9096601 (2015) BindingDB Entry DOI: 10.7270/Q2NS0SNG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epidermal growth factor receptor(L858R, T790M) (Homo sapiens (Human)) | BDBM173455![]() (US9096601, 8-30) | PDB MMDB KEGG B.MOAD DrugBank GoogleScholar | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 228 | n/a | n/a | n/a | n/a | n/a | n/a |
CSPC Zhongqi Pharmaceutical Technology (Shijiazhuang) Co., Ltd. US Patent | Assay Description The object of this assay was to test the inventive compounds for the kinase inhibitory activity in vitro. In this assay, an isotopic labeling method ... | US Patent US9096601 (2015) BindingDB Entry DOI: 10.7270/Q2NS0SNG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epidermal growth factor receptor(L858R, T790M) (Homo sapiens (Human)) | BDBM173463![]() (US9096601, 8-38) | PDB MMDB KEGG B.MOAD DrugBank GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 37 | n/a | n/a | n/a | n/a | n/a | n/a |
CSPC Zhongqi Pharmaceutical Technology (Shijiazhuang) Co., Ltd. US Patent | Assay Description The object of this assay was to test the inventive compounds for the kinase inhibitory activity in vitro. In this assay, an isotopic labeling method ... | US Patent US9096601 (2015) BindingDB Entry DOI: 10.7270/Q2NS0SNG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epidermal growth factor receptor(L858R, T790M) (Homo sapiens (Human)) | BDBM173427![]() (US9096601, 8-1) | PDB MMDB KEGG B.MOAD DrugBank GoogleScholar | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 90 | n/a | n/a | n/a | n/a | n/a | n/a |
CSPC Zhongqi Pharmaceutical Technology (Shijiazhuang) Co., Ltd. US Patent | Assay Description The object of this assay was to test the inventive compounds for the kinase inhibitory activity in vitro. In this assay, an isotopic labeling method ... | US Patent US9096601 (2015) BindingDB Entry DOI: 10.7270/Q2NS0SNG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epidermal growth factor receptor(L858R, T790M) (Homo sapiens (Human)) | BDBM173428![]() (US9096601, 8-2) | PDB MMDB KEGG B.MOAD DrugBank GoogleScholar | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
CSPC Zhongqi Pharmaceutical Technology (Shijiazhuang) Co., Ltd. US Patent | Assay Description The object of this assay was to test the inventive compounds for the kinase inhibitory activity in vitro. In this assay, an isotopic labeling method ... | US Patent US9096601 (2015) BindingDB Entry DOI: 10.7270/Q2NS0SNG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epidermal growth factor receptor(L858R, T790M) (Homo sapiens (Human)) | BDBM173429![]() (US9096601, 8-3) | PDB MMDB KEGG B.MOAD DrugBank GoogleScholar | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 245 | n/a | n/a | n/a | n/a | n/a | n/a |
CSPC Zhongqi Pharmaceutical Technology (Shijiazhuang) Co., Ltd. US Patent | Assay Description The object of this assay was to test the inventive compounds for the kinase inhibitory activity in vitro. In this assay, an isotopic labeling method ... | US Patent US9096601 (2015) BindingDB Entry DOI: 10.7270/Q2NS0SNG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epidermal growth factor receptor(L858R, T790M) (Homo sapiens (Human)) | BDBM173430![]() (US9096601, 8-4 | US9096601, 8-6) | PDB MMDB KEGG B.MOAD DrugBank GoogleScholar | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 46 | n/a | n/a | n/a | n/a | n/a | n/a |
CSPC Zhongqi Pharmaceutical Technology (Shijiazhuang) Co., Ltd. US Patent | Assay Description The object of this assay was to test the inventive compounds for the kinase inhibitory activity in vitro. In this assay, an isotopic labeling method ... | US Patent US9096601 (2015) BindingDB Entry DOI: 10.7270/Q2NS0SNG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epidermal growth factor receptor(L858R, T790M) (Homo sapiens (Human)) | BDBM173431![]() (US9096601, 8-5) | PDB MMDB KEGG B.MOAD DrugBank GoogleScholar | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
CSPC Zhongqi Pharmaceutical Technology (Shijiazhuang) Co., Ltd. US Patent | Assay Description The object of this assay was to test the inventive compounds for the kinase inhibitory activity in vitro. In this assay, an isotopic labeling method ... | US Patent US9096601 (2015) BindingDB Entry DOI: 10.7270/Q2NS0SNG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epidermal growth factor receptor(L858R, T790M) (Homo sapiens (Human)) | BDBM173430![]() (US9096601, 8-4 | US9096601, 8-6) | PDB MMDB KEGG B.MOAD DrugBank GoogleScholar | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 18 | n/a | n/a | n/a | n/a | n/a | n/a |
CSPC Zhongqi Pharmaceutical Technology (Shijiazhuang) Co., Ltd. US Patent | Assay Description The object of this assay was to test the inventive compounds for the kinase inhibitory activity in vitro. In this assay, an isotopic labeling method ... | US Patent US9096601 (2015) BindingDB Entry DOI: 10.7270/Q2NS0SNG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epidermal growth factor receptor(L858R, T790M) (Homo sapiens (Human)) | BDBM173433![]() (US9096601, 8-7) | PDB MMDB KEGG B.MOAD DrugBank GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 128 | n/a | n/a | n/a | n/a | n/a | n/a |
CSPC Zhongqi Pharmaceutical Technology (Shijiazhuang) Co., Ltd. US Patent | Assay Description The object of this assay was to test the inventive compounds for the kinase inhibitory activity in vitro. In this assay, an isotopic labeling method ... | US Patent US9096601 (2015) BindingDB Entry DOI: 10.7270/Q2NS0SNG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epidermal growth factor receptor(L858R, T790M) (Homo sapiens (Human)) | BDBM173435![]() (US9096601, 8-9) | PDB MMDB KEGG B.MOAD DrugBank GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
CSPC Zhongqi Pharmaceutical Technology (Shijiazhuang) Co., Ltd. US Patent | Assay Description The object of this assay was to test the inventive compounds for the kinase inhibitory activity in vitro. In this assay, an isotopic labeling method ... | US Patent US9096601 (2015) BindingDB Entry DOI: 10.7270/Q2NS0SNG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epidermal growth factor receptor(L858R, T790M) (Homo sapiens (Human)) | BDBM173436![]() (US9096601, 8-10) | PDB MMDB KEGG B.MOAD DrugBank GoogleScholar | PC cid PC sid PDB UniChem Similars | PDB US Patent | n/a | n/a | 46 | n/a | n/a | n/a | n/a | n/a | n/a |
CSPC Zhongqi Pharmaceutical Technology (Shijiazhuang) Co., Ltd. US Patent | Assay Description The object of this assay was to test the inventive compounds for the kinase inhibitory activity in vitro. In this assay, an isotopic labeling method ... | US Patent US9096601 (2015) BindingDB Entry DOI: 10.7270/Q2NS0SNG | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
Epidermal growth factor receptor(L858R, T790M) (Homo sapiens (Human)) | BDBM173437![]() (US9096601, 8-11) | PDB MMDB KEGG B.MOAD DrugBank GoogleScholar | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
CSPC Zhongqi Pharmaceutical Technology (Shijiazhuang) Co., Ltd. US Patent | Assay Description The object of this assay was to test the inventive compounds for the kinase inhibitory activity in vitro. In this assay, an isotopic labeling method ... | US Patent US9096601 (2015) BindingDB Entry DOI: 10.7270/Q2NS0SNG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epidermal growth factor receptor(L858R, T790M) (Homo sapiens (Human)) | BDBM173438![]() (US9096601, 8-12) | PDB MMDB KEGG B.MOAD DrugBank GoogleScholar | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
CSPC Zhongqi Pharmaceutical Technology (Shijiazhuang) Co., Ltd. US Patent | Assay Description The object of this assay was to test the inventive compounds for the kinase inhibitory activity in vitro. In this assay, an isotopic labeling method ... | US Patent US9096601 (2015) BindingDB Entry DOI: 10.7270/Q2NS0SNG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epidermal growth factor receptor(L858R, T790M) (Homo sapiens (Human)) | BDBM173439![]() (US9096601, 8-13) | PDB MMDB KEGG B.MOAD DrugBank GoogleScholar | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 9 | n/a | n/a | n/a | n/a | n/a | n/a |
CSPC Zhongqi Pharmaceutical Technology (Shijiazhuang) Co., Ltd. US Patent | Assay Description The object of this assay was to test the inventive compounds for the kinase inhibitory activity in vitro. In this assay, an isotopic labeling method ... | US Patent US9096601 (2015) BindingDB Entry DOI: 10.7270/Q2NS0SNG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epidermal growth factor receptor(L858R, T790M) (Homo sapiens (Human)) | BDBM173441![]() (US9096601, 8-15) | PDB MMDB KEGG B.MOAD DrugBank GoogleScholar | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | n/a |
CSPC Zhongqi Pharmaceutical Technology (Shijiazhuang) Co., Ltd. US Patent | Assay Description The object of this assay was to test the inventive compounds for the kinase inhibitory activity in vitro. In this assay, an isotopic labeling method ... | US Patent US9096601 (2015) BindingDB Entry DOI: 10.7270/Q2NS0SNG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epidermal growth factor receptor(L858R, T790M) (Homo sapiens (Human)) | BDBM173442![]() (US9096601, 8-16) | PDB MMDB KEGG B.MOAD DrugBank GoogleScholar | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 12 | n/a | n/a | n/a | n/a | n/a | n/a |
CSPC Zhongqi Pharmaceutical Technology (Shijiazhuang) Co., Ltd. US Patent | Assay Description The object of this assay was to test the inventive compounds for the kinase inhibitory activity in vitro. In this assay, an isotopic labeling method ... | US Patent US9096601 (2015) BindingDB Entry DOI: 10.7270/Q2NS0SNG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epidermal growth factor receptor(L858R, T790M) (Homo sapiens (Human)) | BDBM173443![]() (US9096601, 8-17) | PDB MMDB KEGG B.MOAD DrugBank GoogleScholar | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
CSPC Zhongqi Pharmaceutical Technology (Shijiazhuang) Co., Ltd. US Patent | Assay Description The object of this assay was to test the inventive compounds for the kinase inhibitory activity in vitro. In this assay, an isotopic labeling method ... | US Patent US9096601 (2015) BindingDB Entry DOI: 10.7270/Q2NS0SNG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epidermal growth factor receptor(L858R, T790M) (Homo sapiens (Human)) | BDBM173444![]() (US9096601, 8-18) | PDB MMDB KEGG B.MOAD DrugBank GoogleScholar | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 57 | n/a | n/a | n/a | n/a | n/a | n/a |
CSPC Zhongqi Pharmaceutical Technology (Shijiazhuang) Co., Ltd. US Patent | Assay Description The object of this assay was to test the inventive compounds for the kinase inhibitory activity in vitro. In this assay, an isotopic labeling method ... | US Patent US9096601 (2015) BindingDB Entry DOI: 10.7270/Q2NS0SNG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epidermal growth factor receptor(L858R, T790M) (Homo sapiens (Human)) | BDBM173445![]() (US9096601, 8-19) | PDB MMDB KEGG B.MOAD DrugBank GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
CSPC Zhongqi Pharmaceutical Technology (Shijiazhuang) Co., Ltd. US Patent | Assay Description The object of this assay was to test the inventive compounds for the kinase inhibitory activity in vitro. In this assay, an isotopic labeling method ... | US Patent US9096601 (2015) BindingDB Entry DOI: 10.7270/Q2NS0SNG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epidermal growth factor receptor(L858R, T790M) (Homo sapiens (Human)) | BDBM173447![]() (US9096601, 8-21) | PDB MMDB KEGG B.MOAD DrugBank GoogleScholar | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
CSPC Zhongqi Pharmaceutical Technology (Shijiazhuang) Co., Ltd. US Patent | Assay Description The object of this assay was to test the inventive compounds for the kinase inhibitory activity in vitro. In this assay, an isotopic labeling method ... | US Patent US9096601 (2015) BindingDB Entry DOI: 10.7270/Q2NS0SNG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epidermal growth factor receptor(L858R, T790M) (Homo sapiens (Human)) | BDBM173448![]() (US9096601, 8-22) | PDB MMDB KEGG B.MOAD DrugBank GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 87 | n/a | n/a | n/a | n/a | n/a | n/a |
CSPC Zhongqi Pharmaceutical Technology (Shijiazhuang) Co., Ltd. US Patent | Assay Description The object of this assay was to test the inventive compounds for the kinase inhibitory activity in vitro. In this assay, an isotopic labeling method ... | US Patent US9096601 (2015) BindingDB Entry DOI: 10.7270/Q2NS0SNG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epidermal growth factor receptor(L858R, T790M) (Homo sapiens (Human)) | BDBM173449![]() (US9096601, 8-23) | PDB MMDB KEGG B.MOAD DrugBank GoogleScholar | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 41 | n/a | n/a | n/a | n/a | n/a | n/a |
CSPC Zhongqi Pharmaceutical Technology (Shijiazhuang) Co., Ltd. US Patent | Assay Description The object of this assay was to test the inventive compounds for the kinase inhibitory activity in vitro. In this assay, an isotopic labeling method ... | US Patent US9096601 (2015) BindingDB Entry DOI: 10.7270/Q2NS0SNG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epidermal growth factor receptor(L858R, T790M) (Homo sapiens (Human)) | BDBM202369![]() (US10081606, Compound I-1 | US9238629, I-1 | US9765...) | PDB MMDB KEGG B.MOAD DrugBank GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 5.5 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Celgene Avilomics Research, Inc. US Patent | Assay Description Briefly, 10x stocks of EGFR-WT (PV3872) from Invitrogen and EGFR-T790M/L858R (40350) from BPS Bioscience, San Diego, Calif., 1.13x ATP (AS001A) and... | US Patent US9238629 (2016) BindingDB Entry DOI: 10.7270/Q2P849Q7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epidermal growth factor receptor(L858R, T790M) (Homo sapiens (Human)) | BDBM202370![]() (US10081606, Compound I-2 | US9238629, I-2 | US9765...) | PDB MMDB KEGG B.MOAD DrugBank GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 5.5 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Celgene Avilomics Research, Inc. US Patent | Assay Description Briefly, 10x stocks of EGFR-WT (PV3872) from Invitrogen and EGFR-T790M/L858R (40350) from BPS Bioscience, San Diego, Calif., 1.13x ATP (AS001A) and... | US Patent US9238629 (2016) BindingDB Entry DOI: 10.7270/Q2P849Q7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epidermal growth factor receptor(L858R, T790M) (Homo sapiens (Human)) | BDBM202371![]() (US10081606, Compound I-3 | US9238629, I-3 | US9765...) | PDB MMDB KEGG B.MOAD DrugBank GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <1 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Celgene Avilomics Research, Inc. US Patent | Assay Description Briefly, 10x stocks of EGFR-WT (PV3872) from Invitrogen and EGFR-T790M/L858R (40350) from BPS Bioscience, San Diego, Calif., 1.13x ATP (AS001A) and... | US Patent US9238629 (2016) BindingDB Entry DOI: 10.7270/Q2P849Q7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epidermal growth factor receptor(L858R, T790M) (Homo sapiens (Human)) | BDBM202372![]() (US10081606, Compound I-4 | US9238629, I-4 | US9765...) | PDB MMDB KEGG B.MOAD DrugBank GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | 5.5 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Celgene Avilomics Research, Inc. US Patent | Assay Description Briefly, 10x stocks of EGFR-WT (PV3872) from Invitrogen and EGFR-T790M/L858R (40350) from BPS Bioscience, San Diego, Calif., 1.13x ATP (AS001A) and... | US Patent US9238629 (2016) BindingDB Entry DOI: 10.7270/Q2P849Q7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epidermal growth factor receptor(L858R, T790M) (Homo sapiens (Human)) | BDBM202373![]() (US10081606, Compound I-5 | US9238629, I-5 | US9765...) | PDB MMDB KEGG B.MOAD DrugBank GoogleScholar | PC cid PC sid UniChem | US Patent | n/a | n/a | <1 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Celgene Avilomics Research, Inc. US Patent | Assay Description Briefly, 10x stocks of EGFR-WT (PV3872) from Invitrogen and EGFR-T790M/L858R (40350) from BPS Bioscience, San Diego, Calif., 1.13x ATP (AS001A) and... | US Patent US9238629 (2016) BindingDB Entry DOI: 10.7270/Q2P849Q7 | |||||||||||
More data for this Ligand-Target Pair |
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