Compile Data Set for Download or QSAR

Found 488 hits Enz. Inhib. hit(s) with Target = 'Free fatty acid receptor 2'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Free fatty acid receptor 2 (Homo sapiens)	BDBM271161 (7-(2,3-difluorobenzenesulfonyl)-4-(2,2-dimethylmor...) Show SMILES Cc1nc(N2CCOC(C)(C)C2)c2[nH]c(N)c(c2n1)S(=O)(=O)c1cccc(F)c1F Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	UniChem		n/a	n/a	n/a	n/a	1	n/a	n/a	n/a	n/a
TAKEDA PHARMACEUTICAL COMPANY LIMITED US Patent					Assay Description GPR43 agonist/PAM activity was determined by measuring changes in intracellular calcium levels using a Ca2+ sensitive fluorescent dye. The changes in...				US Patent US10059713 (2018)
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens)	BDBM271162 (7-(2-fluoro-4-methoxybenzenesulfonyl)-2-methyl-4-[...) Show SMILES COc1ccc(c(F)c1)S(=O)(=O)c1c(N)[nH]c2c(nc(C)nc12)N1CCO[C@@H](C1)C(F)(F)F Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	UniChem		n/a	n/a	n/a	n/a	1	n/a	n/a	n/a	n/a
TAKEDA PHARMACEUTICAL COMPANY LIMITED US Patent					Assay Description GPR43 agonist/PAM activity was determined by measuring changes in intracellular calcium levels using a Ca2+ sensitive fluorescent dye. The changes in...				US Patent US10059713 (2018)
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens)	BDBM271179 (7-(2-fluorobenzenesulfonyl)-N2-methyl-4-(2-methylm...) Show SMILES CNc1nc(N2CCOC(C)C2)c2[nH]c(N)c(c2n1)S(=O)(=O)c1ccccc1F Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	UniChem		n/a	n/a	n/a	n/a	1	n/a	n/a	n/a	n/a
TAKEDA PHARMACEUTICAL COMPANY LIMITED US Patent					Assay Description GPR43 agonist/PAM activity was determined by measuring changes in intracellular calcium levels using a Ca2+ sensitive fluorescent dye. The changes in...				US Patent US10059713 (2018)
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens)	BDBM271169 (7-(2-fluorobenzenesulfonyl)-2-methyl-4-[(2R)-2-(tr...) Show SMILES Cc1nc(N2CCO[C@H](C2)C(F)(F)F)c2[nH]c(N)c(c2n1)S(=O)(=O)c1ccc(F)cc1F Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	UniChem		n/a	n/a	n/a	n/a	1	n/a	n/a	n/a	n/a
TAKEDA PHARMACEUTICAL COMPANY LIMITED US Patent					Assay Description GPR43 agonist/PAM activity was determined by measuring changes in intracellular calcium levels using a Ca2+ sensitive fluorescent dye. The changes in...				US Patent US10059713 (2018)
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens)	BDBM271163 (7-(4-chloro-2-fluorobenzenesulfonyl)-2-methyl-4-[(...) Show SMILES Cc1nc(N2CCO[C@@H](C2)C(F)(F)F)c2[nH]c(N)c(c2n1)S(=O)(=O)c1ccc(Cl)cc1F Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	UniChem		n/a	n/a	n/a	n/a	1	n/a	n/a	n/a	n/a
TAKEDA PHARMACEUTICAL COMPANY LIMITED US Patent					Assay Description GPR43 agonist/PAM activity was determined by measuring changes in intracellular calcium levels using a Ca2+ sensitive fluorescent dye. The changes in...				US Patent US10059713 (2018)
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens)	BDBM271119 (7-(benzenesulfonyl)-4-(2-methylmorpholin-4-yl)-2-(...) Show SMILES CSc1nc(N2CCOC(C)C2)c2[nH]c(N)c(c2n1)S(=O)(=O)c1ccccc1 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	UniChem		n/a	n/a	n/a	n/a	2	n/a	n/a	n/a	n/a
TAKEDA PHARMACEUTICAL COMPANY LIMITED US Patent					Assay Description GPR43 agonist/PAM activity was determined by measuring changes in intracellular calcium levels using a Ca2+ sensitive fluorescent dye. The changes in...				US Patent US10059713 (2018)
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens)	BDBM271121 (7-(benzenesulfonyl)-2-methyl-4-(propan-2-yloxy)-5H...) Show SMILES CC(C)Oc1nc(C)nc2c(c(N)[nH]c12)S(=O)(=O)c1ccccc1 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	UniChem		n/a	n/a	n/a	n/a	2	n/a	n/a	n/a	n/a
TAKEDA PHARMACEUTICAL COMPANY LIMITED US Patent					Assay Description GPR43 agonist/PAM activity was determined by measuring changes in intracellular calcium levels using a Ca2+ sensitive fluorescent dye. The changes in...				US Patent US10059713 (2018)
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens)	BDBM271164 (7-(2,4-difluorobenzenesulfonyl)-2-methyl-4-[(2S)-2...) Show SMILES Cc1nc(N2CCO[C@@H](C2)C(F)(F)F)c2[nH]c(N)c(c2n1)S(=O)(=O)c1ccc(F)cc1F Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	UniChem		n/a	n/a	n/a	n/a	2	n/a	n/a	n/a	n/a
TAKEDA PHARMACEUTICAL COMPANY LIMITED US Patent					Assay Description GPR43 agonist/PAM activity was determined by measuring changes in intracellular calcium levels using a Ca2+ sensitive fluorescent dye. The changes in...				US Patent US10059713 (2018)
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens)	BDBM271165 (7-(2,3-difluorobenzenesulfonyl)-2-methyl-4-[(2S)-2...) Show SMILES Cc1nc(N2CCO[C@@H](C2)C(F)(F)F)c2[nH]c(N)c(c2n1)S(=O)(=O)c1cccc(F)c1F Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	UniChem		n/a	n/a	n/a	n/a	2	n/a	n/a	n/a	n/a
TAKEDA PHARMACEUTICAL COMPANY LIMITED US Patent					Assay Description GPR43 agonist/PAM activity was determined by measuring changes in intracellular calcium levels using a Ca2+ sensitive fluorescent dye. The changes in...				US Patent US10059713 (2018)
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens)	BDBM271170 (7-(2-fluorobenzenesulfonyl)-2-methyl-4-[(2R)-2-(tr...) Show SMILES Cc1nc(N2CCO[C@H](C2)C(F)(F)F)c2[nH]c(N)c(c2n1)S(=O)(=O)c1ccccc1F Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	UniChem		n/a	n/a	n/a	n/a	2	n/a	n/a	n/a	n/a
TAKEDA PHARMACEUTICAL COMPANY LIMITED US Patent					Assay Description GPR43 agonist/PAM activity was determined by measuring changes in intracellular calcium levels using a Ca2+ sensitive fluorescent dye. The changes in...				US Patent US10059713 (2018)
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens)	BDBM271115 (4-(2-methylmorpholin-4-yl)-7-(phenylsulfanyl)-5H-p...) Show SMILES CC1CN(CCO1)c1ncnc2c(Sc3ccccc3)c(N)[nH]c12 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	UniChem		n/a	n/a	n/a	n/a	2	n/a	n/a	n/a	n/a
TAKEDA PHARMACEUTICAL COMPANY LIMITED US Patent					Assay Description GPR43 agonist/PAM activity was determined by measuring changes in intracellular calcium levels using a Ca2+ sensitive fluorescent dye. The changes in...				US Patent US10059713 (2018)
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens)	BDBM271177 (7-(4-chloro-2-fluorobenzenesulfonyl)-2-methyl-4-[(...) Show SMILES Cc1nc(N2CCO[C@H](C2)C(F)(F)F)c2[nH]c(N)c(c2n1)S(=O)(=O)c1ccc(Cl)cc1F Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	UniChem		n/a	n/a	n/a	n/a	2	n/a	n/a	n/a	n/a
TAKEDA PHARMACEUTICAL COMPANY LIMITED US Patent					Assay Description GPR43 agonist/PAM activity was determined by measuring changes in intracellular calcium levels using a Ca2+ sensitive fluorescent dye. The changes in...				US Patent US10059713 (2018)
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens)	BDBM271182 (7-(2-fluorobenzenesulfonyl)-2-(methylsulfanyl)-4-[...) Show SMILES CSc1nc(N2CCOC(C2)C(F)(F)F)c2[nH]c(N)c(c2n1)S(=O)(=O)c1ccccc1F Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	UniChem		n/a	n/a	n/a	n/a	2	n/a	n/a	n/a	n/a
TAKEDA PHARMACEUTICAL COMPANY LIMITED US Patent					Assay Description GPR43 agonist/PAM activity was determined by measuring changes in intracellular calcium levels using a Ca2+ sensitive fluorescent dye. The changes in...				US Patent US10059713 (2018)
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens)	BDBM271098 (7-(benzenesulfonyl)-4-[(2R,5R)-2,5-dimethylmorphol...) Show SMILES C[C@@H]1CN([C@H](C)CO1)c1nc(C)nc2c(c(N)[nH]c12)S(=O)(=O)c1ccccc1 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	UniChem		n/a	n/a	n/a	n/a	2	n/a	n/a	n/a	n/a
TAKEDA PHARMACEUTICAL COMPANY LIMITED US Patent					Assay Description GPR43 agonist/PAM activity was determined by measuring changes in intracellular calcium levels using a Ca2+ sensitive fluorescent dye. The changes in...				US Patent US10059713 (2018)
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens)	BDBM271111 (7-(2-fluorobenzenesulfonyl)-2-methyl-4-[2-(trifluo...) Show SMILES Cc1nc(N2CCOC(C2)C(F)(F)F)c2[nH]c(N)c(c2n1)S(=O)(=O)c1ccccc1F Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	UniChem		n/a	n/a	n/a	n/a	2	n/a	n/a	n/a	n/a
TAKEDA PHARMACEUTICAL COMPANY LIMITED US Patent					Assay Description GPR43 agonist/PAM activity was determined by measuring changes in intracellular calcium levels using a Ca2+ sensitive fluorescent dye. The changes in...				US Patent US10059713 (2018)
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens)	BDBM271173 (7-(2,5-difluorobenzenesulfonyl)-2-methyl-4-[(2S)-2...) Show SMILES Cc1nc(N2CCO[C@@H](C2)C(F)(F)F)c2[nH]c(N)c(c2n1)S(=O)(=O)c1cc(F)ccc1F Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	UniChem		n/a	n/a	n/a	n/a	2	n/a	n/a	n/a	n/a
TAKEDA PHARMACEUTICAL COMPANY LIMITED US Patent					Assay Description GPR43 agonist/PAM activity was determined by measuring changes in intracellular calcium levels using a Ca2+ sensitive fluorescent dye. The changes in...				US Patent US10059713 (2018)
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens)	BDBM271146 (7-(3-fluorobenzenesulfonyl)-4-(2-methylmorpholin-4...) Show SMILES CC1CN(CCO1)c1nc(nc2c(c(N)[nH]c12)S(=O)(=O)c1cccc(F)c1)C(F)(F)F Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	UniChem		n/a	n/a	n/a	n/a	3	n/a	n/a	n/a	n/a
TAKEDA PHARMACEUTICAL COMPANY LIMITED US Patent					Assay Description GPR43 agonist/PAM activity was determined by measuring changes in intracellular calcium levels using a Ca2+ sensitive fluorescent dye. The changes in...				US Patent US10059713 (2018)
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens)	BDBM271160 (7-(2-fluorobenzenesulfonyl)-2-methyl-4-[(2S)-2-(tr...) Show SMILES Cc1nc(N2CCO[C@@H](C2)C(F)(F)F)c2[nH]c(N)c(c2n1)S(=O)(=O)c1ccccc1F Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	UniChem		n/a	n/a	n/a	n/a	3	n/a	n/a	n/a	n/a
TAKEDA PHARMACEUTICAL COMPANY LIMITED US Patent					Assay Description GPR43 agonist/PAM activity was determined by measuring changes in intracellular calcium levels using a Ca2+ sensitive fluorescent dye. The changes in...				US Patent US10059713 (2018)
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens)	BDBM271166 (7-(2,6-difluorobenzenesulfonyl)-4-(2,2-dimethylmor...) Show SMILES Cc1nc(N2CCOC(C)(C)C2)c2[nH]c(N)c(c2n1)S(=O)(=O)c1c(F)cccc1F Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	UniChem		n/a	n/a	n/a	n/a	3	n/a	n/a	n/a	n/a
TAKEDA PHARMACEUTICAL COMPANY LIMITED US Patent					Assay Description GPR43 agonist/PAM activity was determined by measuring changes in intracellular calcium levels using a Ca2+ sensitive fluorescent dye. The changes in...				US Patent US10059713 (2018)
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens)	BDBM271171 (7-(2-fluorobenzenesulfonyl)-2-methyl-4-[(2R)-2-(tr...) Show SMILES Cc1nc(N2CCO[C@H](C2)C(F)(F)F)c2[nH]c(N)c(c2n1)S(=O)(=O)c1cc(F)ccc1F Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	UniChem		n/a	n/a	n/a	n/a	3	n/a	n/a	n/a	n/a
TAKEDA PHARMACEUTICAL COMPANY LIMITED US Patent					Assay Description GPR43 agonist/PAM activity was determined by measuring changes in intracellular calcium levels using a Ca2+ sensitive fluorescent dye. The changes in...				US Patent US10059713 (2018)
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens)	BDBM271172 (7-(2-fluoro-4-methoxybenzenesulfonyl)-2-methyl-4-[...) Show SMILES COc1ccc(c(F)c1)S(=O)(=O)c1c(N)[nH]c2c(nc(C)nc12)N1CCO[C@H](C1)C(F)(F)F Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	UniChem		n/a	n/a	n/a	n/a	3	n/a	n/a	n/a	n/a
TAKEDA PHARMACEUTICAL COMPANY LIMITED US Patent					Assay Description GPR43 agonist/PAM activity was determined by measuring changes in intracellular calcium levels using a Ca2+ sensitive fluorescent dye. The changes in...				US Patent US10059713 (2018)
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens)	BDBM270890 (7-(benzenesulfonyl)-4-(piperidin-1-yl)-5H-pyrrolo[...) Show SMILES Nc1[nH]c2c(ncnc2c1S(=O)(=O)c1ccccc1)N1CCCCC1 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	UniChem		n/a	n/a	n/a	n/a	3	n/a	n/a	n/a	n/a
TAKEDA PHARMACEUTICAL COMPANY LIMITED US Patent					Assay Description GPR43 agonist/PAM activity was determined by measuring changes in intracellular calcium levels using a Ca2+ sensitive fluorescent dye. The changes in...				US Patent US10059713 (2018)
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens)	BDBM271183 (7-(2-fluorobenzenesulfonyl)-2-methyl-4-[2-methyl-2...) Show SMILES Cc1nc(N2CCOC(C)(C2)C(F)(F)F)c2[nH]c(N)c(c2n1)S(=O)(=O)c1ccccc1F Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	UniChem		n/a	n/a	n/a	n/a	3	n/a	n/a	n/a	n/a
TAKEDA PHARMACEUTICAL COMPANY LIMITED US Patent					Assay Description GPR43 agonist/PAM activity was determined by measuring changes in intracellular calcium levels using a Ca2+ sensitive fluorescent dye. The changes in...				US Patent US10059713 (2018)
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens)	BDBM271088 (4-cyclopentyl-7-(3-fluorobenzenesulfonyl)-2-methyl...) Show SMILES Cc1nc(C2CCCC2)c2[nH]c(N)c(c2n1)S(=O)(=O)c1cccc(F)c1 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	UniChem		n/a	n/a	n/a	n/a	3	n/a	n/a	n/a	n/a
TAKEDA PHARMACEUTICAL COMPANY LIMITED US Patent					Assay Description GPR43 agonist/PAM activity was determined by measuring changes in intracellular calcium levels using a Ca2+ sensitive fluorescent dye. The changes in...				US Patent US10059713 (2018)
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens)	BDBM271112 (7-(2-fluoro-4-methoxybenzenesulfonyl)-2-methyl-4-[...) Show SMILES COc1ccc(c(F)c1)S(=O)(=O)c1c(N)[nH]c2c(nc(C)nc12)N1CCO[C@@H](C)C1 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	UniChem		n/a	n/a	n/a	n/a	3	n/a	n/a	n/a	n/a
TAKEDA PHARMACEUTICAL COMPANY LIMITED US Patent					Assay Description GPR43 agonist/PAM activity was determined by measuring changes in intracellular calcium levels using a Ca2+ sensitive fluorescent dye. The changes in...				US Patent US10059713 (2018)
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens)	BDBM271113 (4-[(2R,5R)-2,5-dimethylmorpholin-4-yl]-7-(2-fluoro...) Show SMILES C[C@@H]1CN([C@H](C)CO1)c1nc(C)nc2c(c(N)[nH]c12)S(=O)(=O)c1ccccc1F Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	UniChem		n/a	n/a	n/a	n/a	3	n/a	n/a	n/a	n/a
TAKEDA PHARMACEUTICAL COMPANY LIMITED US Patent					Assay Description GPR43 agonist/PAM activity was determined by measuring changes in intracellular calcium levels using a Ca2+ sensitive fluorescent dye. The changes in...				US Patent US10059713 (2018)
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens)	BDBM271175 (4-[(2,2-dimethyloxan-3-yl)oxy]-7-(2-fluorobenzenes...) Show SMILES Cc1nc(OC2CCCOC2(C)C)c2[nH]c(N)c(c2n1)S(=O)(=O)c1ccccc1F Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	UniChem		n/a	n/a	n/a	n/a	3	n/a	n/a	n/a	n/a
TAKEDA PHARMACEUTICAL COMPANY LIMITED US Patent					Assay Description GPR43 agonist/PAM activity was determined by measuring changes in intracellular calcium levels using a Ca2+ sensitive fluorescent dye. The changes in...				US Patent US10059713 (2018)
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens)	BDBM271147 (7-(2-fluoro-5-methoxybenzenesulfonyl)-2-methyl-4-(...) Show SMILES COc1ccc(F)c(c1)S(=O)(=O)c1c(N)[nH]c2c(nc(C)nc12)N1CCOC(C)C1 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	UniChem		n/a	n/a	n/a	n/a	4	n/a	n/a	n/a	n/a
TAKEDA PHARMACEUTICAL COMPANY LIMITED US Patent					Assay Description GPR43 agonist/PAM activity was determined by measuring changes in intracellular calcium levels using a Ca2+ sensitive fluorescent dye. The changes in...				US Patent US10059713 (2018)
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens)	BDBM271077 (7-(benzenesulfonyl)-4-(2-ethylthiomorpholin-4-yl)-...) Show SMILES CCC1CN(CCS1)c1ncnc2c(c(N)[nH]c12)S(=O)(=O)c1ccccc1 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	UniChem		n/a	n/a	n/a	n/a	4	n/a	n/a	n/a	n/a
TAKEDA PHARMACEUTICAL COMPANY LIMITED US Patent					Assay Description GPR43 agonist/PAM activity was determined by measuring changes in intracellular calcium levels using a Ca2+ sensitive fluorescent dye. The changes in...				US Patent US10059713 (2018)
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens)	BDBM271174 (7-(2,6-Difluorobenzenesulfonyl)-2-methyl-4-[(2S)-2...) Show SMILES Cc1nc(N2CCO[C@@H](C2)C(F)(F)F)c2[nH]c(N)c(c2n1)S(=O)(=O)c1c(F)cccc1F Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	UniChem		n/a	n/a	n/a	n/a	4	n/a	n/a	n/a	n/a
TAKEDA PHARMACEUTICAL COMPANY LIMITED US Patent					Assay Description GPR43 agonist/PAM activity was determined by measuring changes in intracellular calcium levels using a Ca2+ sensitive fluorescent dye. The changes in...				US Patent US10059713 (2018)
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens)	BDBM271159 (7-(4-chloro-2-fluorobenzenesulfonyl)-4-(2,2-dimeth...) Show SMILES Cc1nc(N2CCOC(C)(C)C2)c2[nH]c(N)c(c2n1)S(=O)(=O)c1ccc(Cl)cc1F Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	UniChem		n/a	n/a	n/a	n/a	4	n/a	n/a	n/a	n/a
TAKEDA PHARMACEUTICAL COMPANY LIMITED US Patent					Assay Description GPR43 agonist/PAM activity was determined by measuring changes in intracellular calcium levels using a Ca2+ sensitive fluorescent dye. The changes in...				US Patent US10059713 (2018)
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens)	BDBM271142 (7-(2,6-difluorobenzenesulfonyl)-2-methyl-4-(2-meth...) Show SMILES CC1CN(CCO1)c1nc(C)nc2c(c(N)[nH]c12)S(=O)(=O)c1c(F)cccc1F Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	UniChem		n/a	n/a	n/a	n/a	5	n/a	n/a	n/a	n/a
TAKEDA PHARMACEUTICAL COMPANY LIMITED US Patent					Assay Description GPR43 agonist/PAM activity was determined by measuring changes in intracellular calcium levels using a Ca2+ sensitive fluorescent dye. The changes in...				US Patent US10059713 (2018)
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens)	BDBM271067 (7-(benzenesulfonyl)-4-N-ethyl-4-N-(oxan-4-ylmethyl...) Show SMILES CCN(CC1CCOCC1)c1ncnc2c(c(N)[nH]c12)S(=O)(=O)c1ccccc1 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	UniChem		n/a	n/a	n/a	n/a	5	n/a	n/a	n/a	n/a
TAKEDA PHARMACEUTICAL COMPANY LIMITED US Patent					Assay Description GPR43 agonist/PAM activity was determined by measuring changes in intracellular calcium levels using a Ca2+ sensitive fluorescent dye. The changes in...				US Patent US10059713 (2018)
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens)	BDBM271178 (7-(2-fluorobenzenesulfonyl)-4-[(2R)-2-(fluoromethy...) Show SMILES Cc1nc(N2CCO[C@@H](CF)C2)c2[nH]c(N)c(c2n1)S(=O)(=O)c1ccccc1F Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	UniChem		n/a	n/a	n/a	n/a	5	n/a	n/a	n/a	n/a
TAKEDA PHARMACEUTICAL COMPANY LIMITED US Patent					Assay Description GPR43 agonist/PAM activity was determined by measuring changes in intracellular calcium levels using a Ca2+ sensitive fluorescent dye. The changes in...				US Patent US10059713 (2018)
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens)	BDBM271155 (7-(2-fluorobenzenesulfonyl)-2-methyl-4-[(1,1,1-tri...) Show SMILES CC(Oc1nc(C)nc2c(c(N)[nH]c12)S(=O)(=O)c1ccccc1F)C(F)(F)F Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	UniChem		n/a	n/a	n/a	n/a	5	n/a	n/a	n/a	n/a
TAKEDA PHARMACEUTICAL COMPANY LIMITED US Patent					Assay Description GPR43 agonist/PAM activity was determined by measuring changes in intracellular calcium levels using a Ca2+ sensitive fluorescent dye. The changes in...				US Patent US10059713 (2018)
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens)	BDBM271143 (7-(2,4-difluorobenzenesulfonyl)-2-methyl-4-(2-meth...) Show SMILES CC1CN(CCO1)c1nc(C)nc2c(c(N)[nH]c12)S(=O)(=O)c1ccc(F)cc1F Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	UniChem		n/a	n/a	n/a	n/a	6	n/a	n/a	n/a	n/a
TAKEDA PHARMACEUTICAL COMPANY LIMITED US Patent					Assay Description GPR43 agonist/PAM activity was determined by measuring changes in intracellular calcium levels using a Ca2+ sensitive fluorescent dye. The changes in...				US Patent US10059713 (2018)
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens)	BDBM271158 (3-(benzenesulfonyl)-7-(2,2-dimethylmorpholin-4-yl)...) Show SMILES CC1(C)CN(CCO1)c1ccnc2c(c(N)[nH]c12)S(=O)(=O)c1ccccc1 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	UniChem		n/a	n/a	n/a	n/a	6	n/a	n/a	n/a	n/a
TAKEDA PHARMACEUTICAL COMPANY LIMITED US Patent					Assay Description GPR43 agonist/PAM activity was determined by measuring changes in intracellular calcium levels using a Ca2+ sensitive fluorescent dye. The changes in...				US Patent US10059713 (2018)
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens)	BDBM271020 (7-(benzenesulfonyl)-4-[(2R,6S)-2,6-dimethylmorphol...) Show SMILES C[C@H]1CN(C[C@@H](C)O1)c1nc(C)nc2c(c(N)[nH]c12)S(=O)(=O)c1ccccc1 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	UniChem		n/a	n/a	n/a	n/a	6	n/a	n/a	n/a	n/a
TAKEDA PHARMACEUTICAL COMPANY LIMITED US Patent					Assay Description GPR43 agonist/PAM activity was determined by measuring changes in intracellular calcium levels using a Ca2+ sensitive fluorescent dye. The changes in...				US Patent US10059713 (2018)
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens)	BDBM271097 (7-(2-fluorobenzenesulfonyl)-2-methyl-4-[(2S)-2-met...) Show SMILES C[C@H]1CN(CCO1)c1nc(C)nc2c(c(N)[nH]c12)S(=O)(=O)c1ccccc1F Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	UniChem		n/a	n/a	n/a	n/a	6	n/a	n/a	n/a	n/a
TAKEDA PHARMACEUTICAL COMPANY LIMITED US Patent					Assay Description GPR43 agonist/PAM activity was determined by measuring changes in intracellular calcium levels using a Ca2+ sensitive fluorescent dye. The changes in...				US Patent US10059713 (2018)
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens)	BDBM271062 (4-(4,4-difluoropiperidin-1-yl)-7-(3-fluorobenzenes...) Show SMILES Cc1nc(N2CCC(F)(F)CC2)c2[nH]c(N)c(c2n1)S(=O)(=O)c1cccc(F)c1 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	UniChem		n/a	n/a	n/a	n/a	6	n/a	n/a	n/a	n/a
TAKEDA PHARMACEUTICAL COMPANY LIMITED US Patent					Assay Description GPR43 agonist/PAM activity was determined by measuring changes in intracellular calcium levels using a Ca2+ sensitive fluorescent dye. The changes in...				US Patent US10059713 (2018)
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens)	BDBM271065 (7-(benzenesulfonyl)-4-[2-(propan-2-yl)morpholin-4-...) Show SMILES CC(C)C1CN(CCO1)c1ncnc2c(c(N)[nH]c12)S(=O)(=O)c1ccccc1 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	UniChem		n/a	n/a	n/a	n/a	6	n/a	n/a	n/a	n/a
TAKEDA PHARMACEUTICAL COMPANY LIMITED US Patent					Assay Description GPR43 agonist/PAM activity was determined by measuring changes in intracellular calcium levels using a Ca2+ sensitive fluorescent dye. The changes in...				US Patent US10059713 (2018)
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens)	BDBM271057 (7-(2-fluorobenzenesulfonyl)-2-methyl-4-{6-oxa-9-az...) Show SMILES Cc1nc(N2CCOC3(CCCC3)C2)c2[nH]c(N)c(c2n1)S(=O)(=O)c1ccccc1F Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	UniChem		n/a	n/a	n/a	n/a	6	n/a	n/a	n/a	n/a
TAKEDA PHARMACEUTICAL COMPANY LIMITED US Patent					Assay Description GPR43 agonist/PAM activity was determined by measuring changes in intracellular calcium levels using a Ca2+ sensitive fluorescent dye. The changes in...				US Patent US10059713 (2018)
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens)	BDBM271085 (US10059713, Example 206) Show SMILES CC1CN(CCO1)c1ncnc2c(c(N)[nH]c12)S(=O)(=O)C1CCN(CC1)C(=O)OCc1ccccc1 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	UniChem		n/a	n/a	n/a	n/a	7	n/a	n/a	n/a	n/a
TAKEDA PHARMACEUTICAL COMPANY LIMITED US Patent					Assay Description GPR43 agonist/PAM activity was determined by measuring changes in intracellular calcium levels using a Ca2+ sensitive fluorescent dye. The changes in...				US Patent US10059713 (2018)
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens)	BDBM271109 (7-(benzenesulfonyl)-4-(1-cyclopropylethoxy)-2-meth...) Show SMILES CC(Oc1nc(C)nc2c(c(N)[nH]c12)S(=O)(=O)c1ccccc1)C1CC1 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	UniChem		n/a	n/a	n/a	n/a	7	n/a	n/a	n/a	n/a
TAKEDA PHARMACEUTICAL COMPANY LIMITED US Patent					Assay Description GPR43 agonist/PAM activity was determined by measuring changes in intracellular calcium levels using a Ca2+ sensitive fluorescent dye. The changes in...				US Patent US10059713 (2018)
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens)	BDBM271103 (7-(2-fluorobenzenesulfonyl)-2-methyl-4-(prop-1-en-...) Show SMILES CC(=C)c1nc(C)nc2c(c(N)[nH]c12)S(=O)(=O)c1ccccc1F Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	UniChem		n/a	n/a	n/a	n/a	7	n/a	n/a	n/a	n/a
TAKEDA PHARMACEUTICAL COMPANY LIMITED US Patent					Assay Description GPR43 agonist/PAM activity was determined by measuring changes in intracellular calcium levels using a Ca2+ sensitive fluorescent dye. The changes in...				US Patent US10059713 (2018)
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens)	BDBM271117 (7-(2-fluorobenzenesulfonyl)-2-methyl-4-{5-oxa-8-az...) Show SMILES Cc1nc(N2CCOC3(CCC3)C2)c2[nH]c(N)c(c2n1)S(=O)(=O)c1ccccc1F Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	UniChem		n/a	n/a	n/a	n/a	8	n/a	n/a	n/a	n/a
TAKEDA PHARMACEUTICAL COMPANY LIMITED US Patent					Assay Description GPR43 agonist/PAM activity was determined by measuring changes in intracellular calcium levels using a Ca2+ sensitive fluorescent dye. The changes in...				US Patent US10059713 (2018)
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens)	BDBM271151 (7-(2-fluorobenzenesulfonyl)-2-methyl-4-(propan-2-y...) Show SMILES CC(C)Oc1nc(C)nc2c(c(N)[nH]c12)S(=O)(=O)c1ccccc1F Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	UniChem		n/a	n/a	n/a	n/a	8	n/a	n/a	n/a	n/a
TAKEDA PHARMACEUTICAL COMPANY LIMITED US Patent					Assay Description GPR43 agonist/PAM activity was determined by measuring changes in intracellular calcium levels using a Ca2+ sensitive fluorescent dye. The changes in...				US Patent US10059713 (2018)
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens)	BDBM271075 (7-(benzenesulfonyl)-4-(2-methylthiomorpholin-4-yl)...) Show SMILES CC1CN(CCS1)c1ncnc2c(c(N)[nH]c12)S(=O)(=O)c1ccccc1 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	UniChem		n/a	n/a	n/a	n/a	8	n/a	n/a	n/a	n/a
TAKEDA PHARMACEUTICAL COMPANY LIMITED US Patent					Assay Description GPR43 agonist/PAM activity was determined by measuring changes in intracellular calcium levels using a Ca2+ sensitive fluorescent dye. The changes in...				US Patent US10059713 (2018)
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens)	BDBM271168 (7-(2,5-difluorobenzenesulfonyl)-4-(2,2-dimethylmor...) Show SMILES Cc1nc(N2CCOC(C)(C)C2)c2[nH]c(N)c(c2n1)S(=O)(=O)c1cc(F)ccc1F Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	UniChem		n/a	n/a	n/a	n/a	8	n/a	n/a	n/a	n/a
TAKEDA PHARMACEUTICAL COMPANY LIMITED US Patent					Assay Description GPR43 agonist/PAM activity was determined by measuring changes in intracellular calcium levels using a Ca2+ sensitive fluorescent dye. The changes in...				US Patent US10059713 (2018)
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens)	BDBM271056 (US10059713, Example 175) Show SMILES Nc1[nH]c2c(OCC3CC3(F)F)ncnc2c1S(=O)(=O)c1ccccc1 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	UniChem		n/a	n/a	n/a	n/a	8	n/a	n/a	n/a	n/a
TAKEDA PHARMACEUTICAL COMPANY LIMITED US Patent					Assay Description GPR43 agonist/PAM activity was determined by measuring changes in intracellular calcium levels using a Ca2+ sensitive fluorescent dye. The changes in...				US Patent US10059713 (2018)
					More data for this Ligand-Target Pair

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