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Found 1067 Enz. Inhib. hit(s) with Target = 'Fructose-1,6-bisphosphatase 1'
TargetFructose-1,6-bisphosphatase 1(Homo sapiens (Human))
Boston College

Curated by ChEMBL
LigandPNGBDBM50293594(5-(2-amino-5-isobutylthiazol-4-yl)furan-2-ylphosph...)
Affinity DataEC50:  16nMAssay Description:Inhibition of human liver FBPaseMore data for this Ligand-Target Pair
TargetFructose-1,6-bisphosphatase 1(Mus musculus)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50305579(5-(2-methoxyethyl)-4-methyl-N-(4-methyl-5-(methylt...)
Affinity DataEC50:  2.40E+3nMAssay Description:Inhibition of FBPase in mouse liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFructose-1,6-bisphosphatase 1(Mus musculus)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50305580(5-(2-hydroxyethyl)-4-methyl-N-(4-methyl-5-(methylt...)
Affinity DataEC50:  2.80E+3nMAssay Description:Inhibition of FBPase in mouse liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFructose-1,6-bisphosphatase 1(Mus musculus)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50305567(CHEMBL589863 | N-(5-bromothiazol-2-ylcarbamoyl)-5-...)
Affinity DataEC50:  3.20E+3nMAssay Description:Inhibition of FBPase in mouse liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFructose-1,6-bisphosphatase 1(Mus musculus)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50305581(CHEMBL590363 | N-(4-ethyl-5-(methylthio)thiazol-2-...)
Affinity DataEC50:  5.30E+3nMAssay Description:Inhibition of FBPase in mouse liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFructose-1,6-bisphosphatase 1(Mus musculus)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50305565(CHEMBL590361 | N-(5-bromothiazol-2-ylcarbamoyl)-5-...)
Affinity DataEC50:  5.50E+3nMAssay Description:Inhibition of FBPase in mouse liverMore data for this Ligand-Target Pair
TargetFructose-1,6-bisphosphatase 1(Mus musculus)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50305576(CHEMBL601267 | N-(5-bromothiazol-2-ylcarbamoyl)-7-...)
Affinity DataEC50:  6.30E+3nMAssay Description:Inhibition of FBPase in mouse liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFructose-1,6-bisphosphatase 1(Mus musculus)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50305578(5-(2-methoxyethyl)-4-methyl-N-(5-(methylthio)thiaz...)
Affinity DataEC50:  6.50E+3nMAssay Description:Inhibition of FBPase in mouse liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFructose-1,6-bisphosphatase 1(Mus musculus)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50305583(CHEMBL600654 | N-(5-ethyl-4-methylthiazol-2-ylcarb...)
Affinity DataEC50:  8.10E+3nMAssay Description:Inhibition of FBPase in mouse liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFructose-1,6-bisphosphatase 1(Mus musculus)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50305572(CHEMBL590111 | N-(5-bromothiazol-2-ylcarbamoyl)-5-...)
Affinity DataEC50:  9.00E+3nMAssay Description:Inhibition of FBPase in mouse liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFructose-1,6-bisphosphatase 1(Mus musculus)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50305571(CHEMBL601691 | N-(5-bromothiazol-2-ylcarbamoyl)-5-...)
Affinity DataEC50:  9.00E+3nMAssay Description:Inhibition of FBPase in mouse liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFructose-1,6-bisphosphatase 1(Mus musculus)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50305582(CHEMBL602789 | N-(4-ethyl-5-methoxythiazol-2-ylcar...)
Affinity DataEC50:  9.20E+3nMAssay Description:Inhibition of FBPase in mouse liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFructose-1,6-bisphosphatase 1(Mus musculus)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50305563(CHEMBL590360 | N-(5-bromothiazol-2-ylcarbamoyl)-5-...)
Affinity DataEC50:  1.00E+4nMAssay Description:Inhibition of FBPase in mouse liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFructose-1,6-bisphosphatase 1(Mus musculus)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50305557(CHEMBL611631 | N-(5-bromothiazol-2-ylcarbamoyl)-4-...)
Affinity DataEC50:  1.00E+4nMAssay Description:Inhibition of FBPase in mouse liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFructose-1,6-bisphosphatase 1(Mus musculus)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50305594(5-(2-hydroxyethyl)-4-methyl-N-(4-methyl-5-(trifluo...)
Affinity DataEC50:  1.00E+4nMAssay Description:Inhibition of FBPase in mouse liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFructose-1,6-bisphosphatase 1(Mus musculus)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50305568(CHEMBL585620 | N-(5-bromothiazol-2-ylcarbamoyl)-5-...)
Affinity DataEC50:  1.20E+4nMAssay Description:Inhibition of FBPase in mouse liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFructose-1,6-bisphosphatase 1(Mus musculus)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50305562(CHEMBL590359 | N-(5-bromothiazol-2-ylcarbamoyl)-5-...)
Affinity DataEC50:  1.30E+4nMAssay Description:Inhibition of FBPase in mouse liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFructose-1,6-bisphosphatase 1(Mus musculus)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50305575(CHEMBL590113 | N-(5-bromothiazol-2-ylcarbamoyl)-7-...)
Affinity DataEC50:  1.40E+4nMAssay Description:Inhibition of FBPase in mouse liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFructose-1,6-bisphosphatase 1(Mus musculus)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50305577(CHEMBL590362 | N-(5-bromo-4-methylthiazol-2-ylcarb...)
Affinity DataEC50:  1.40E+4nMAssay Description:Inhibition of FBPase in mouse liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFructose-1,6-bisphosphatase 1(Mus musculus)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50305574(CHEMBL590840 | N-(5-bromothiazol-2-ylcarbamoyl)-1-...)
Affinity DataEC50:  1.40E+4nMAssay Description:Inhibition of FBPase in mouse liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFructose-1,6-bisphosphatase 1(Mus musculus)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50305595(CHEMBL591317 | N-(7-chloro-4-methoxybenzo[d]thiazo...)
Affinity DataEC50:  1.50E+4nMAssay Description:Inhibition of FBPase in mouse liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFructose-1,6-bisphosphatase 1(Mus musculus)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50305573(CHEMBL590839 | N-(5-bromothiazol-2-ylcarbamoyl)-5-...)
Affinity DataEC50:  1.80E+4nMAssay Description:Inhibition of FBPase in mouse liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFructose-1,6-bisphosphatase 1(Mus musculus)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50305569(CHEMBL590597 | N-(5-bromothiazol-2-ylcarbamoyl)-5-...)
Affinity DataEC50:  1.90E+4nMAssay Description:Inhibition of FBPase in mouse liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFructose-1,6-bisphosphatase 1(Mus musculus)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50305586(CHEMBL589862 | N-(5-bromothiazol-2-ylcarbamoyl)-3,...)
Affinity DataEC50:  1.90E+4nMAssay Description:Inhibition of FBPase in mouse liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFructose-1,6-bisphosphatase 1(Mus musculus)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50305585(CHEMBL589861 | N-(5-bromothiazol-2-ylcarbamoyl)-3-...)
Affinity DataEC50:  2.30E+4nMAssay Description:Inhibition of FBPase in mouse liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFructose-1,6-bisphosphatase 1(Mus musculus)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50305590(CHEMBL595150 | N-(5-bromothiazol-2-ylcarbamoyl)-3-...)
Affinity DataEC50:  2.40E+4nMAssay Description:Inhibition of FBPase in mouse liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFructose-1,6-bisphosphatase 1(Mus musculus)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50305561(CHEMBL593282 | N-(5-bromothiazol-2-ylcarbamoyl)-5-...)
Affinity DataEC50:  2.40E+4nMAssay Description:Inhibition of FBPase in mouse liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFructose-1,6-bisphosphatase 1(Mus musculus)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50305566(CHEMBL585961 | N-(5-bromothiazol-2-ylcarbamoyl)-6,...)
Affinity DataEC50:  2.70E+4nMAssay Description:Inhibition of FBPase in mouse liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFructose-1,6-bisphosphatase 1(Mus musculus)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50305587(CHEMBL589137 | N-(5-bromothiazol-2-ylcarbamoyl)-3-...)
Affinity DataEC50:  3.20E+4nMAssay Description:Inhibition of FBPase in mouse liverMore data for this Ligand-Target Pair
TargetFructose-1,6-bisphosphatase 1(Mus musculus)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50305570(CHEMBL589865 | N-(5-bromothiazol-2-ylcarbamoyl)-5-...)
Affinity DataEC50:  3.40E+4nMAssay Description:Inhibition of FBPase in mouse liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFructose-1,6-bisphosphatase 1(Mus musculus)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50305564(CHEMBL600653 | N-(5-bromothiazol-2-ylcarbamoyl)-5-...)
Affinity DataEC50:  4.20E+4nMAssay Description:Inhibition of FBPase in mouse liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFructose-1,6-bisphosphatase 1(Mus musculus)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50305589(CHEMBL595149 | N-(5-bromothiazol-2-ylcarbamoyl)-3-...)
Affinity DataEC50:  4.90E+4nMAssay Description:Inhibition of FBPase in mouse liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB

TargetFructose-1,6-bisphosphatase 1(Mus musculus)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50305558(CHEMBL594444 | N-(5-bromothiazol-2-ylcarbamoyl)-4-...)
Affinity DataEC50:  6.20E+4nMAssay Description:Inhibition of FBPase in mouse liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFructose-1,6-bisphosphatase 1(Mus musculus)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50305556(CHEMBL595529 | N-(5-bromothiazol-2-ylcarbamoyl)-2-...)
Affinity DataEC50:  6.30E+4nMAssay Description:Inhibition of FBPase in mouse liverMore data for this Ligand-Target Pair
TargetFructose-1,6-bisphosphatase 1(Mus musculus)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50305592(CHEMBL608398 | N-(5-bromothiazol-2-ylcarbamoyl)-3-...)
Affinity DataEC50:  7.40E+4nMAssay Description:Inhibition of FBPase in mouse liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFructose-1,6-bisphosphatase 1(Mus musculus)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50305560(4-bromo-N-(5-bromothiazol-2-ylcarbamoyl)-5-chlorot...)
Affinity DataEC50:  8.70E+4nMAssay Description:Inhibition of FBPase in mouse liverMore data for this Ligand-Target Pair
TargetFructose-1,6-bisphosphatase 1(Mus musculus)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50305559(CHEMBL594445 | N-(5-bromothiazol-2-ylcarbamoyl)-5-...)
Affinity DataEC50:  9.20E+4nMAssay Description:Inhibition of FBPase in mouse liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFructose-1,6-bisphosphatase 1(Mus musculus)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50305593(3-amino-N-(5-bromothiazol-2-ylcarbamoyl)benzenesul...)
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of FBPase in mouse liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFructose-1,6-bisphosphatase 1(Mus musculus)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50305588(CHEMBL607540 | N-(5-bromothiazol-2-ylcarbamoyl)-2-...)
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of FBPase in mouse liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFructose-1,6-bisphosphatase 1(Mus musculus)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50305591(CHEMBL594668 | N-(5-bromothiazol-2-ylcarbamoyl)-3-...)
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of FBPase in mouse liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFructose-1,6-bisphosphatase 1(Mus musculus)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50305584(CHEMBL595067 | N-(5-bromothiazol-2-ylcarbamoyl)-4-...)
Affinity DataEC50:  1.18E+5nMAssay Description:Inhibition of FBPase in mouse liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB

TargetFructose-1,6-bisphosphatase 1(Sus scrofa (Pig))
Boston College

US Patent
LigandPNGBDBM209638(US9273021, Usnic Acid)
Affinity DataIC50:  9.30E+5nMpH: 7.5Assay Description:FBPase activity was measured spectrophotometrically by employing the coupling enzymes phosphoglucose isomerase and glucose-6-phosphate dehydrogenase....More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetFructose-1,6-bisphosphatase 1(Sus scrofa (Pig))
Boston College

US Patent
LigandPNGBDBM50316378(1,1'-(1,3,7,9-Tetrahydroxydibenzofuran-2,6-diyl)bi...)
Affinity DataIC50:  1.50E+3nMpH: 7.5Assay Description:FBPase activity was measured spectrophotometrically by employing the coupling enzymes phosphoglucose isomerase and glucose-6-phosphate dehydrogenase....More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetFructose-1,6-bisphosphatase 1(Sus scrofa (Pig))
Boston College

US Patent
LigandPNGBDBM50316379(1,1'-(1,3,7,9-Tetrahydroxydibenzofuran-2,6-diyl)bi...)
Affinity DataIC50:  5.00E+3nMpH: 7.5Assay Description:FBPase activity was measured spectrophotometrically by employing the coupling enzymes phosphoglucose isomerase and glucose-6-phosphate dehydrogenase....More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetFructose-1,6-bisphosphatase 1(Homo sapiens (Human))
Boston College

Curated by ChEMBL
LigandPNGBDBM209638(US9273021, Usnic Acid)
Affinity DataIC50:  3.71E+5nMpH: 7.5Assay Description:FBPase activity was measured spectrophotometrically by employing the coupling enzymes phosphoglucose isomerase and glucose-6-phosphate dehydrogenase....More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetFructose-1,6-bisphosphatase 1(Homo sapiens (Human))
Boston College

Curated by ChEMBL
LigandPNGBDBM50316378(1,1'-(1,3,7,9-Tetrahydroxydibenzofuran-2,6-diyl)bi...)
Affinity DataIC50:  8.10E+3nMpH: 7.5Assay Description:FBPase activity was measured spectrophotometrically by employing the coupling enzymes phosphoglucose isomerase and glucose-6-phosphate dehydrogenase....More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetFructose-1,6-bisphosphatase 1(Homo sapiens (Human))
Boston College

Curated by ChEMBL
LigandPNGBDBM50316379(1,1'-(1,3,7,9-Tetrahydroxydibenzofuran-2,6-diyl)bi...)
Affinity DataIC50:  6.00E+3nMpH: 7.5Assay Description:FBPase activity was measured spectrophotometrically by employing the coupling enzymes phosphoglucose isomerase and glucose-6-phosphate dehydrogenase....More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetFructose-1,6-bisphosphatase 1(Rattus norvegicus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50117947((6,7-Diethoxy-quinazolin-4-yl)-[3-(2-methyl-thiazo...)
Affinity DataIC50:  3.80E+3nMAssay Description:Concentration required for 50% Inhibition against (F16BP) Fructose-1,6-bisphosphatase in rat single mutant(Gln55His) enzyme using malachite green ass...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFructose-1,6-bisphosphatase 1(Rattus norvegicus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50117955(4-[3-(6,7-Diethoxy-quinazolin-4-ylamino)-phenyl]-t...)
Affinity DataIC50:  3.00E+3nMAssay Description:Concentration required for 50% Inhibition against (F16BP) Fructose-1,6-bisphosphatase in rat single mutant (Gln55His) enzyme using malachite green as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFructose-1,6-bisphosphatase 1(Rattus norvegicus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50117957(CHEMBL123678 | {4-[3-(6,7-Diethoxy-quinazolin-4-yl...)
Affinity DataIC50:  2.90E+3nMAssay Description:Concentration required for 50% Inhibition against (F16BP) Fructose-1,6-bisphosphatase in rat single mutant (Gln55His) enzyme using malachite green as...More data for this Ligand-Target Pair
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